XRCC6

General Information

Gene Name       : XRCC6
Gene ID             : ENSG00000196419.12
Essential Gene : Yes

Functions

Localization(RBPImage: XRCC6)

Domains (AlphaFold: XRCC6)


Antibody Validation

 View validation images for all XRCC6 antibodies

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878XRCC6ENSG00000196419.12297.10301.52299.31ENCSR000AEF
HepG2XRCC6ENSG00000196419.12317.13388.89353.01ENCSR985KAT
K562XRCC6ENSG00000196419.12259.12256.19257.65ENCSR000AEO

Assays

7 Released experiments are available on ENCORE database.

Assay TypeExp_NameENCODE IDTarget labelBiosampleStatusLinked AntibodyControlsMethodNote
eCLIPeCLIP: 311ENCSR571ROLXRCC6HepG2ReleasedENCAB462RZDENCSR044NGV  
eCLIPeCLIP: 480ENCSR258QKOXRCC6K562ReleasedENCAB462RZDENCSR687HHB  
knockdown followed by RNA-seq XRCC6-BGKLV13-K562ENCSR232CPDXRCC6K562ReleasedENCSR815CVQ   shRNAKD% = 52.0,46.0
knockdown followed by RNA-seq XRCC6-BGHLV14-HepG2ENCSR500WHEXRCC6HepG2ReleasedENCSR491FOC   shRNAKD% = 35.0,37.1
knockdown followed by RNA-seq XRCC6-BGKcLV15-K562ENCSR516EPTXRCC6K562ReleasedENCSR404OHQ   CRISPRKD% = 71.0,67.9
knockdown followed by RNA-seq XRCC6-BGHcLV16-HepG2ENCSR312VLSXRCC6HepG2ReleasedENCSR964HKT   CRISPRKD% = 80.2,71.6
RNA Bind-n-SeqRBNS: XRCC6ENCSR189MABXRCC6cell-free sampleReleasedENCSR790NTP  






  eCLIP  
  RBP    Exp_UID    Cell_Line    ENCODE_ACCESSION    Control_ENCODE_ACCESSION    ENCODE_Antibody_ID    Antibody    Lot_num    Status    Project  
XRCC6311HepG2ENCSR571ROLENCSR044NGVENCAB462RZDA302-624A1ReleasedENCODE3
XRCC6480K562ENCSR258QKOENCSR687HHBENCAB462RZDA302-624A1ReleasedENCODE3


  Antibody Validation  
  GeneName    Antibody_DCC_ID    Product_ID    Lot_ID    Phosphate    HepG2 Primary Validation    K562 Primary Validation    HepG2 Secondary Validation    K562 Secondary Validation  
XRCC6ENCAB462RZDA302-624A1Released, ENCODE3Released, ENCODE3BGHLV14-69, Released, ENCODE3BGKLV13-23, Released, ENCODE3
XRCC6ENCAB611VLVMA5-13110TL2692924BGHcLV16-59, Released, ENCODE4BGKcLV15-61, Released, ENCODE4
XRCC6ENCAB101BKX200995CD1112Released, ENCODE3BGKcLV15-61, Released, ENCODE4


  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
XRCC6K562shRNAENCSR232CPDENCSR815CVQXRCC6_BGKLV13_23,XRCC6_BGKLV13_24NT_BGKLV13_1,NT_BGKLV13_252.0,46.0ReleasedENCODE3
XRCC6HepG2shRNAENCSR500WHEENCSR491FOCXRCC6_BGHLV14-69,XRCC6_BGHLV14-70NT_BGHLV14-1,NT_BGHLV14-235.0,37.1ReleasedENCODE3
XRCC6K562CRISPRENCSR516EPTENCSR404OHQXRCC6-BGKcLV15-61,XRCC6-BGKcLV15-62NT-BGKcLV15-1,NT-BGKcLV15-271.0,67.9ReleasedENCODE4
XRCC6HepG2CRISPRENCSR312VLSENCSR964HKTXRCC6-BGHcLV16-59,XRCC6-BGHcLV16-60NT-BGHcLV16-1,NT-BGHcLV16-280.2,71.6ReleasedENCODE4


  RNA Bind-n-Seqn  
  GeneName    gene_aliases    Status    Project    Note  
XRCC6XRCC6ReleasedENCODE4


  Localization Image in HepG2  
    XRCC6: Click to RBP Image Database
  • Nuclei
  • Nucleoplasm
  • Cytoplasm
  • Compartment/Organelle
  • Unknown Cyto Territory
  • Nuclear release mitosis












    • RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela
    XRCC6Product_ID: A302-624A
    Lot_ID: 1
    Source: Bethyl Labs
    Target Name: XRCC6-human    		 HepG2_Bethyl_A302-624A_1_XRCC6.png<br>Caption: IP-Western Blot analysis of HepG2 whole cell lysate using XRCC6 specific antibody. Lane 1 is 1% of twenty million whole cell lysate input and lane 2 is 25% of IP enrichment using rabbit normal IgG (lanes under 'IgG'). Lane 3 is 1% of twenty million whole cell lysate input and lane 4 is 10% IP enrichment using rabbit polyclonal anti-XRCC6 antibody (lanes under 'XRCC6').
    		 Ku70_xrcc6_Secondary_Western.png<br>Caption: Western blot following shRNA against XRCC6 in K562 and HepG2 whole cell lysate using XRCC6 specific antibody. Lane 1 is a ladder, lane 2 is K562 non-targeting control knockdown, lane 3 and 4 are two different shRNAs against XRCC6. Lanes 5-8 follow the same pattern, but in HepG2. XRCC6 protein appears as the green band, Tubulin serves as a control and appears in red.
    		 K562_Bethyl_A302-624A_1_XRCC6.png<br>Caption: IP-Western Blot analysis of K562 whole cell lysate using XRCC6 specific antibody. Lane 1 is 1% of twenty million whole cell lysate input and lane 2 is 10% of IP enrichment using rabbit normal IgG (lanes under 'IgG'). Lane 3 is 1% of twenty million whole cell lysate input and lane 4 is 10% IP enrichment using rabbit polyclonal anti-XRCC6 antibody (lanes under 'XRCC6').
    		 Ku70_xrcc6_Secondary_Western.png<br>Caption: Western blot following shRNA against XRCC6 in K562 and HepG2 whole cell lysate using XRCC6 specific antibody. Lane 1 is a ladder, lane 2 is K562 non-targeting control knockdown, lane 3 and 4 are two different shRNAs against XRCC6. Lanes 5-8 follow the same pattern, but in HepG2. XRCC6 protein appears as the green band, Tubulin serves as a control and appears in red.
    XRCC6Product_ID: 200995
    Lot_ID: CD1112
    Source: Zen Bioscience
    Target Name: XRCC6-human    		 XRCC6_HepG2.png<br>Caption: IP-Western Blot analysis of HepG2 whole cell lysate using XRCC6 specific antibody. Lane 1 is 3% of ten million whole cell lysate input (lane under '15% input') , lane 2 is 20% of IP enrichment using mouse normal IgG (lane under 'IgG') and lane 3 is 20% IP enrichment using mouse monoclonal anti-XRCC6 antibody (lanes under 'anti-XRCC6').
    XRCC6Product_ID: MA5-13110
    Lot_ID: TL2692924
    Source: Thermo Fisher
    Target Name: XRCC6-human    		 XRCC6-HEPG2-CRISPR-MA5-13110.png<br>Caption: Western blot following CRISPR against XRCC6 in HepG2 whole cell lysate using XRCC6 specific antibody. Lane 1 is a ladder, lane 2 is HepG2 non-targeting control knockdown, lane 3 and 4 are two different CRISPR against XRCC6. XRCC6 protein appears as the green arrow, Beta-actin serves as a control and appears in red arrow.
    		 XRCC6-K562-CRISPR-MA5-13110.png<br>Caption: Western blot following CRISPR against XRCC6 in K562 whole cell lysate using XRCC6 specific antibody. Lane 1 is a ladder, lane 2 is K562 non-targeting control knockdown, lane 3 and 4 are two different CRISPR against XRCC6. XRCC6 protein appears as the green arrow, Beta-actin serves as a control and appears in red arrow.








    RNA Targets
    • XRCC6 protein binds to 889 RNA regions.  




    • The binding motifs of XRCC6

      • Trulli

    Proteins bound to RNA
    • XRCC6 RNA is bound by 28 proteins.  






    XRCC6 protein has 889 RNA targets:

    Only display 100 entries as example. Please click "View All" button to see all 889 entries.     

    RBP Chr Start End Strand log2(fold change) -log(p-value) Cell Line Matched Gene Matched Area
    XRCC6chr214522344445223528+3.560205.82617K562RRP1CDS
    XRCC6chr222354771623547772+6.5817135.42129K562BCRintron-Distal
    XRCC6chr119550403095504087-4.182173.37821K562FAM76B3'-UTR,intron-Distal
    XRCC6chr204789688247896913+3.84106400.00000K562ZFAS1intron-Distal
    XRCC6chr47977573979775799+5.3953012.73545K562BMP2Kintron-Distal
    XRCC6chr163008159430081609+3.37568400.00000K562ALDOA3'-UTR,intron-Proximal
    XRCC6chr84887260148872653-4.043403.95668K562PRKDCCDS,intron-Distal
    XRCC6chr99866733698667370+4.6402832.53576K562ERCC6L2intron-Distal
    XRCC6chr1923378042337879+3.165966.69536K562SPPL2Bintron-Distal
    XRCC6chr118537597885376013-3.403973.40391K562CREBZF5'-UTR,intron-Distal
    XRCC6chr12133379934133379990-3.701154.39592K562GOLGA3intron-Distal
    XRCC6chr34573052245730527-4.4540373.11695K562LIMD1-AS1intron-Distal
    XRCC6chr183371642233716471+3.297473.84532K562ELP2intron-Distal,intron-Proximal
    XRCC6chr164732653147326592-4.263923.22788K562ITFG1intron-Distal
    XRCC6chr156679712566797175-4.1606514.69377K562RPL45'-UTR,CDS,intron-Distal,intron-Proximal
    XRCC6chr204789691347896929+3.4339674.71822K562ZFAS1intron-Distal,intron-Proximal
    XRCC6chr117511553275115539+3.5919668.55238K562RPS3intron-Distal
    XRCC6chr5176737680176737755-3.043403.93420K562MXD35'-UTR,CDS,intron-Distal,intron-Proximal
    XRCC6chr206089150260891545-3.611493.84532K562LAMA5intron-Distal
    XRCC6chr1617964501796558+3.9447915.61522K562MAPK8IP3intron-Distal
    XRCC6chr41781194717812025-3.297473.84532K562DCAF16intron-Distal
    XRCC6chr121319906913199115+3.5969636.65386K562KIAA1467intron-Distal
    XRCC6chr11619965916199707+3.652726.40705K562SPENintron-Proximal
    XRCC6chr34573049045730522-4.63876400.00000K562LIMD1-AS1intron-Distal
    XRCC6chr11763896763961+3.403975.41580K562TALDO1CDS,intron-Proximal
    XRCC6chr3195798682195798708-3.313683.46269K562TFRCintron-Distal
    XRCC6chr65696665756966708+3.529174.68720K562ZNF451CDS,intron-Distal
    XRCC6chr31584488415844953-4.589953.96837K562ANKRD28intron-Distal
    XRCC6chr6111136458111136529-4.851739.44917K562CDK195'-UTR,intron-Distal,intron-Proximal
    XRCC6chr14102506627102506654+3.652724.90350K562DYNC1H1CDS
    XRCC6chr7148507092148507148-5.2657018.01266K562EZH2intron-Distal
    XRCC6chr114718651047186559-4.750924.62348K562ARFGAP23'-UTR,intron-Distal
    XRCC6chr1615024961502566-3.395436.78344K562CLCN7intron-Distal
    XRCC6chr750855295085602+3.471434.68720K562RBAK, RBAK-RBAKDN5'-UTR,intron-Distal,intron-Proximal
    XRCC6chr28554633585546349-3.273753.69087HepG2TGOLN23'-UTR,intron-Distal
    XRCC6chr213546963435469686+3.786465.41741K562SLC5A3, MRPS6, AP000320.73'-UTR,CDS,intron-Distal
    XRCC6chr116155725661557306-3.152723.40391K562TMEM2583'-UTR,CDS,intron-Distal,intron-Proximal
    XRCC6chr162386591923865964+4.717363.41592K562PRKCBintron-Distal
    XRCC6chr1774112457411293+4.612444.24741HepG2POLR2Aintron-Distal
    XRCC6chr204303537343035430+3.793723.58200HepG2HNF4Aintron-Distal
    XRCC6chr1268793266879385+3.0795812.39407K562PTMS3'-UTR,CDS,intron-Proximal
    XRCC6chrX153197621153197731-3.323245.89463K562NAA10, ARHGAP4intron-Distal,intron-Proximal
    XRCC6chr177965866679658712+4.530163.68931K562HGSintron-Distal,intron-Proximal
    XRCC6chr79228417792284215-3.840485.32988HepG2CDK6intron-Distal
    XRCC6chr3171846978171847021+4.640015.72464HepG2FNDC3Bintron-Distal
    XRCC6chr2240924223240924336-4.152724.39734K562NDUFA10intron-Distal
    XRCC6chr24740142447401480-5.060685.56900K562CALM2, RP11-761B3.1intron-Distal,intron-Proximal
    XRCC6chr5134116820134116859+3.737683.89592K562DDX46CDS,intron-Proximal
    XRCC6chr168871853088718590-3.104537.49313K562MVD3'-UTR,intron-Distal
    XRCC6chr3185817193185817203-4.479529.98736HepG2ETV5intron-Distal
    XRCC6chr1155238310155238364-4.463865.73820HepG2CLK2intron-Distal
    XRCC6chr714966531496700-3.710463.37821K562MICALL2intron-Distal
    XRCC6chr111709732317097368-3.2809157.59017K562RPS13intron-Distal
    XRCC6chr6111135836111135907-3.433989.59276K562CDK19intron-Distal
    XRCC6chr162365328323653335+4.298576.72556HepG2DCTN5intron-Distal
    XRCC6chr2178129180178129269-3.471434.68720K562NFE2L2CDS,intron-Distal
    XRCC6chr214628994546290053-4.432493.99299HepG2PTTG1IPintron-Distal
    XRCC6chr1155030475155030552+4.871425.08739K562ADAM15CDS
    XRCC6chr163008158330081594+3.1886181.91183K562ALDOA3'-UTR,intron-Proximal
    XRCC6chr158021541180215477-3.313683.46269K562ST20, ST20-MTHFSintron-Distal
    XRCC6chr61664621016646249-4.593465.32726HepG2ATXN1intron-Distal
    XRCC6chr1167611223167611268+3.530163.09172K562RCSD1intron-Distal
    XRCC6chr2132029671132029735+3.445203.09172K562PLEKHB2intron-Distal
    XRCC6chr3171523777171523789-5.013885.29407HepG2PP13439, PLD1intron-Distal
    XRCC6chr212255235422552439+4.974659.92017K562NCAM2intron-Distal
    XRCC6chr12853184028531861-3.360243.84532K562DNAJC8CDS,intron-Distal,intron-Proximal
    XRCC6chr3195798663195798682-3.174923.00168K562TFRCintron-Distal
    XRCC6chr51036623610366292+4.710463.96837K562MARCH6intron-Distal
    XRCC6chr13113209227113209325-3.521203.37821K562TUBGCP3CDS,intron-Distal,intron-Proximal
    XRCC6chr63025879430258848-4.760173.98292HepG2HCG18, HCG17intron-Distal
    XRCC6chr116228764762287690-3.0204810.22283K562AHNAKCDS,intron-Distal
    XRCC6chr2170662671170662719+3.839925.93686K562SSBintron-Distal,intron-Proximal
    XRCC6chr185699610956996132-3.111493.63206K562LMAN13'-UTR,intron-Distal
    XRCC6chr22052540220525447-4.521203.96837K562PUM2intron-Distal
    XRCC6chr14103082803103082812+3.029174.93708K562RCOR1intron-Distal
    XRCC6chr1620152552015294+4.3556220.65121K562SNHG9intron-Distal
    XRCC6chr203359393033593983-3.737683.89592K562TRPC4APintron-Distal
    XRCC6chr1950586285058675+5.145175.08739K562KDM4Bintron-Distal
    XRCC6chr223800675938006820+4.646004.24741HepG2GGA1intron-Distal,intron-Proximal
    XRCC6chrX4700201147002045-4.589956.19917K562NDUFB11CDS,intron-Distal,intron-Proximal
    XRCC6chr1630741073074200+3.334423.78287K562THOC65'-UTR,intron-Proximal
    XRCC6chr203516604835166097-4.924885.08739K562RP5-977B1.7intron-Distal
    XRCC6chr203396174733961800-3.606163.52118K562UQCC1intron-Distal
    XRCC6chr174919782449197872-3.475724.26355K562SPAG9CDS,intron-Distal
    XRCC6chr222130725821307282+4.3824321.42618K562CRKL3'-UTR,intron-Distal
    XRCC6chr129899502798995059+3.682173.52118K562SLC25A33'-UTR,CDS,intron-Distal,intron-Proximal
    XRCC6chr156679361166793632-3.5556818.93704K562RPL4intron-Distal,intron-Proximal
    XRCC6chr2216279214216279268-5.3636925.45025HepG2FN1intron-Distal
    XRCC6chr4890906890961-4.813683.96837K562GAKintron-Distal
    XRCC6chr61626639716266443+3.3054754.62788K562GMPRintron-Distal
    XRCC6chr8145691523145691576+4.652723.22788K562KIFC25'-UTR
    XRCC6chr5177575102177575215+4.348883.41592K562RMND5B3'-UTR
    XRCC6chr111579361158011-3.589953.37821K562SDF4intron-Distal
    XRCC6chr1214819116214819146+3.043403.93420K562CENPFCDS
    XRCC6chr724091132409167+3.403974.99980K562EIF3BCDS
    XRCC6chr3171905436171905550+3.251214.61460HepG2FNDC3Bintron-Distal
    XRCC6chr142353720323537256-4.021016.99902HepG2ACIN1intron-Distal
    XRCC6chr16457286457337+5.152723.22788K562DECR2, NME4intron-Distal,intron-Proximal
    XRCC6chr77618324576183319+3.115554.51517HepG2UPK3B, AC004980.7intron-Distal
    XRCC6chr124675267846752731-4.940468.80706HepG2SLC38A23'-UTR,intron-Distal




    28 proteins are bound to XRCC6 RNA:

    Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
    chr224205980242059880+3'-UTR,CDS3.599916.48534K562FXR2
    chr224205980342059839+3'-UTR,CDS3.530335.53855K562YBX3
    chr224205980842059875+3'-UTR,CDS3.5444711.20378HepG2RPS3
    chr224205996042060039+3'-UTR6.1729512.21991HepG2SUB1
    chr224201798042018097+5'-UTR,CDS,intron-Proximal3.3174711.11291HepG2AQR
    chr224201806342018078+5'-UTR,CDS4.6005121.96565K562UCHL5
    chr224201802242018072+5'-UTR,CDS3.7265016.87739HepG2BCLAF1
    chr224203254842032653+5'-UTR,CDS3.9121112.72310K562FXR2
    chr224201799742018064+5'-UTR,CDS3.3786027.07388K562DDX3X
    chr224201800942018039+5'-UTR,CDS3.3889920.29973K562UCHL5
    chr224203211642032134+5'-UTR,CDS,intron-Distal,intron-Proximal3.141603.47139K562GRWD1
    chr224201803942018063+5'-UTR,CDS4.4982225.03802K562UCHL5
    chr224201807042018091+5'-UTR,CDS,intron-Proximal3.305013.52390K562MTPAP
    chr224201796042018025+5'-UTR,CDS,intron-Proximal3.501505.67192K562SF3B4
    chr224201807242018088+5'-UTR,CDS4.039118.79898HepG2BCLAF1
    chr224201730742017351+5'-UTR,intron-Proximal4.2526624.91923K562DDX3X
    chr224201799242018087+5'-UTR,CDS,intron-Proximal3.060714.47222K562APOBEC3C
    chr224203211542032145+5'-UTR,CDS,intron-Distal,intron-Proximal4.6025416.44038HepG2BCLAF1
    chr224203224042032254+5'-UTR,CDS3.192524.44431HepG2G3BP1
    chr224201808342018118+5'-UTR,CDS,intron-Proximal4.680265.68502HepG2PRPF8
    chr224201733742017349+5'-UTR3.220365.39278K562ZNF622
    chr224203211642032128+5'-UTR,CDS,intron-Distal,intron-Proximal3.057666.11586HepG2G3BP1
    chr224203253942032639+5'-UTR,CDS3.330683.37449K562FXR1
    chr224201799242017997+5'-UTR,intron-Proximal4.6049322.35516K562DDX3X
    chr224203216342032191+5'-UTR,CDS,intron-Proximal3.650848.66838HepG2BCLAF1
    chr224203223442032255+5'-UTR,CDS,intron-Proximal3.103329.64262HepG2BCLAF1
    chr224201799842018096+5'-UTR,CDS,intron-Proximal3.7268616.11380HepG2TRA2A
    chr224201807342018123+5'-UTR,CDS,intron-Proximal3.262246.70706HepG2EFTUD2
    chr224201807842018090+5'-UTR,CDS4.4622218.56855K562UCHL5
    chr224203251942032532+5'-UTR,CDS,intron-Proximal3.403956.30471HepG2G3BP1
    chr224203255542032620+5'-UTR,CDS3.7936111.92573HepG2G3BP1
    chr224201805842018090+5'-UTR,CDS3.4965016.42270K562ZNF622
    chr224203254142032605+5'-UTR,CDS3.2946415.03431HepG2BCLAF1
    chr224203255442032617+5'-UTR,CDS3.6339011.50336K562FMR1
    chr224203212442032194+5'-UTR,CDS,intron-Distal,intron-Proximal3.6158911.68353K562YBX3
    chr224203261742032655+CDS3.802968.46004K562FMR1
    chr224203267142032745+CDS4.2919715.77906HepG2G3BP1
    chr224204305542043084+CDS3.278114.50748HepG2GRWD1
    chr224204304242043085+CDS4.048206.78575K562FMR1
    chr224202421242024229+CDS,intron-Distal3.093443.13733K562CPSF6
    chr224204679542046891+CDS4.3933728.50147K562RPS3
    chr224204685242046916+CDS,intron-Proximal3.079098.60674HepG2BUD13
    chr224205965842059707+CDS3.283737.87634HepG2G3BP1
    chr224204679542046842+CDS3.745429.33213HepG2G3BP1
    chr224203374242033781+CDS3.552157.86771K562ZNF622
    chr224202415642024235+CDS,intron-Distal,intron-Proximal3.859519.63399HepG2SUB1
    chr224202421042024234+CDS,intron-Distal3.453297.78685HepG2GRWD1
    chr224205972542059779+CDS4.860615.48383HepG2LARP4
    chr224205431742054356+CDS5.7921414.66357HepG2G3BP1
    chr224203356142033620+CDS,intron-Proximal3.699637.64728K562AQR
    chr224202417742024203+CDS,intron-Distal4.2936915.60975HepG2GRWD1
    chr224204965842049693+CDS4.025075.68852HepG2RPS3
    chr224202412942024151+CDS,intron-Distal4.829209.66045K562UCHL5
    chr224204685642046895+CDS3.539246.27563K562FMR1
    chr224204679842046892+CDS4.099659.53949HepG2RPS3
    chr224203376842033792+CDS3.325386.74819K562YBX3
    chr224205739742057444+CDS3.438149.26737HepG2G3BP1
    chr224204304342043086+CDS4.9157915.49041HepG2G3BP1
    chr224203272042032758+CDS3.6558110.82062K562YBX3
    chr224204306042043084+CDS3.289927.39995HepG2BCLAF1
    chr224203371842033793+CDS3.1716813.62443HepG2G3BP1
    chr224202415842024205+CDS,intron-Distal3.4183011.06808HepG2G3BP1
    chr224203268042032702+CDS3.2613411.50248K562YBX3
    chr224203360642033633+CDS,intron-Proximal3.113004.38519K562BUD13
    chr224202420542024232+CDS,intron-Distal3.393149.38788HepG2G3BP1
    chr224202412142024147+CDS,intron-Distal,intron-Proximal4.081226.77992K562CPSF6
    chr224203265942032742+CDS4.050213.36793K562FXR1
    chr224204669942046748+CDS,intron-Proximal4.624754.27476HepG2AQR
    chr224204684242046895+CDS4.5643914.40860HepG2G3BP1
    chr224204672642046739+CDS,intron-Proximal4.238097.67223HepG2G3BP1
    chr224202412142024129+CDS,intron-Distal,intron-Proximal4.548268.58706K562UCHL5
    chr224204687942046934+CDS,intron-Proximal3.704039.77953HepG2PRPF8
    chr224202412142024151+CDS,intron-Distal,intron-Proximal3.780565.25158HepG2TRA2A
    chr224202421442024234+CDS,intron-Distal5.1618633.80184HepG2BCLAF1
    chr224203370642033790+CDS4.155709.40228K562GRWD1
    chr224203264342032736+CDS4.735939.05742K562ZNF800
    chr224203269442032770+CDS3.786348.01464K562FMR1
    chr224204294842043023+CDS4.2462916.68780HepG2G3BP1
    chr224205295742053025+CDS4.5391121.18562HepG2G3BP1
    chr224202415542024177+CDS,intron-Distal3.7047510.56926HepG2GRWD1
    chr224202412642024146+CDS,intron-Distal3.419376.33024HepG2BCLAF1
    chr224202415642024214+CDS,intron-Distal4.4547851.58848HepG2BCLAF1
    chr224204307442043119+CDS,intron-Proximal4.031284.16174HepG2PRPF8
    chr224202415342024211+CDS,intron-Distal3.2964410.70472K562ZNF800
    chr224204295242042997+CDS3.372174.87139HepG2FXR2
    chr224204306042043085+CDS3.852795.37099K562FXR2
    chr224204406342044138+intron-Distal4.596736.17909K562ILF3
    chr224205658742056714+intron-Distal3.396104.08242HepG2PTBP1
    chr224203283742032884+intron-Distal,intron-Proximal3.761874.23459K562PRPF8
    chr224203454442034599+intron-Distal6.5925619.48934HepG2XPO5
    chr224204375442043838+intron-Distal4.866698.42494HepG2ILF3
    chr224203723242037303+intron-Distal4.926325.58765HepG2QKI
    chr224203283242032881+intron-Distal,intron-Proximal4.527315.97994K562AQR
    chr224204404742044124+intron-Distal4.8986210.06964HepG2PCBP2
    chr224203450542034544+intron-Distal5.233756.79597HepG2XPO5
    chr224204537142045431+intron-Distal3.605383.00349HepG2ILF3
    chr224204690742046954+intron-Proximal3.945564.52312K562AQR
    chr224203379542033834+intron-Proximal4.280038.44604HepG2PRPF8
    ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




    No autoregularoty interactions between protein XRCC6 and its RNA.



    Diffrential Expression
    • 3,149 differentially expressed genes after Knockdown/Knockout XRCC6 protein.  





    • 118 RBPs can affect the levels of XRCC6.  







    3,149 differentially expressed genes after Knockdown/Knockout XRCC6 protein :

    Only display 100 entries as example. Please click "View All" button to see all 3,149 entries.     

    Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
    NFYAENSG00000001167.101671.261401036.371300.689305.397403.94170HepG2XRCC6
    SEMA3FENSG00000001617.7609.79530324.469000.910103.588702.38190HepG2XRCC6
    CYP51A1ENSG00000001630.112799.270403984.51670-0.509403.566902.36430HepG2XRCC6
    LAP3ENSG00000002549.81776.765702450.12750-0.463602.883101.80300HepG2XRCC6
    CYP26B1ENSG00000003137.424.378303.053102.997204.046302.76740HepG2XRCC6
    DBNDD1ENSG00000003249.91092.72950625.041700.805804.460003.12870HepG2XRCC6
    CASP10ENSG00000003400.10553.82980755.98190-0.448902.287601.32630HepG2XRCC6
    SLC7A2ENSG00000003989.123381.993107195.56340-1.089205.897004.38380HepG2XRCC6
    CDC27ENSG00000004897.73691.158302650.074100.477903.118601.99100HepG2XRCC6
    RPAP3ENSG00000005175.5799.24110563.037500.505302.723901.67730HepG2XRCC6
    ACSM3ENSG00000005187.7733.881201058.19540-0.528003.199402.05720HepG2XRCC6
    GCFC2ENSG00000005436.9943.01500674.735000.482902.303601.33890HepG2XRCC6
    CROTENSG00000005469.7454.18060223.941901.020007.382405.71830HepG2XRCC6
    ABCB4ENSG00000005471.11456.91460879.27390-0.944408.248506.51620HepG2XRCC6
    RHBDD2ENSG00000005486.12613.79770329.009700.899503.592902.38530HepG2XRCC6
    ZNF195ENSG00000005801.12955.79990448.145401.0926010.831608.88990HepG2XRCC6
    ITGALENSG00000005844.1318.4962077.14480-2.060307.150205.51510HepG2XRCC6
    ITGA3ENSG00000005884.13209.5519064.906501.6908011.195109.22140HepG2XRCC6
    ZFXENSG00000005889.11683.537301016.04430-0.571903.622202.40800HepG2XRCC6
    ASB4ENSG00000005981.8209.7138082.345601.348607.871106.16960HepG2XRCC6
    TMEM98ENSG00000006042.71133.359701513.14000-0.416902.256401.30350HepG2XRCC6
    SPATA20ENSG00000006282.151531.21120923.622100.729203.365202.19370HepG2XRCC6
    TNFRSF12AENSG00000006327.9928.93480414.290501.1648012.0438010.00630HepG2XRCC6
    BAIAP2L1ENSG00000006453.91160.48130801.058800.534603.312002.14950HepG2XRCC6
    PHTF2ENSG00000006576.12677.27290356.975500.923807.271605.62020HepG2XRCC6
    DBF4ENSG00000006634.3637.82080446.629500.514002.638701.60830HepG2XRCC6
    IFRD1ENSG00000006652.91100.19010540.748901.024609.994908.11780HepG2XRCC6
    ELAC2ENSG00000006744.141157.33370787.075900.556103.535402.33690HepG2XRCC6
    ADIPOR2ENSG00000006831.92287.482503353.46780-0.551904.011302.73730HepG2XRCC6
    E2F2ENSG00000007968.6141.09830224.14940-0.667802.720201.67500HepG2XRCC6
    AASSENSG00000008311.10399.08300611.08500-0.614702.662201.62840HepG2XRCC6
    MGST1ENSG00000008394.81411.806202097.68350-0.571304.079702.79760HepG2XRCC6
    CRY1ENSG00000008405.7523.64590322.031400.701304.170802.87720HepG2XRCC6
    ST3GAL1ENSG00000008513.10607.982801616.98440-1.4112019.1728016.72720HepG2XRCC6
    IL32ENSG00000008517.122712.414302016.231200.427802.581301.56190HepG2XRCC6
    REV3LENSG00000009413.112498.177201519.418400.717306.080704.54710HepG2XRCC6
    SPRTNENSG00000010072.11290.93890161.197200.851804.490803.15510HepG2XRCC6
    GIPRENSG00000010310.425.6330063.53440-1.309503.274602.11930HepG2XRCC6
    SEMA3GENSG00000010319.2334.09210695.66310-1.058107.726006.03370HepG2XRCC6
    HIVEP2ENSG00000010818.4828.138401337.77860-0.691905.142703.72320HepG2XRCC6
    CLCN6ENSG00000011021.171020.170001446.83080-0.504103.112401.98560HepG2XRCC6
    TSPAN9ENSG00000011105.7667.03760930.32960-0.480002.625201.59670HepG2XRCC6
    SYT7ENSG00000011347.570.03200257.73540-1.8798015.0299012.78390HepG2XRCC6
    BRCA1ENSG00000012048.15805.109501089.91900-0.437002.355901.37830HepG2XRCC6
    NR1H4ENSG00000012504.9596.75830969.09540-0.699505.019603.61910HepG2XRCC6
    CALCOCO1ENSG00000012822.11622.993801034.50880-0.731705.505304.04170HepG2XRCC6
    PSMC4ENSG00000013275.31736.059001262.510300.459402.768201.71370HepG2XRCC6
    MAN2B2ENSG00000013288.4837.41160516.920700.695904.806703.42980HepG2XRCC6
    MVPENSG00000013364.141068.36490597.809200.837503.535802.33690HepG2XRCC6
    MAMLD1ENSG00000013619.933.723105.731302.556704.642703.28690HepG2XRCC6
    POLA2ENSG00000014138.4254.82330399.00880-0.646903.345402.17630HepG2XRCC6
    CAPN1ENSG00000014216.111844.553901200.156900.619902.949901.85370HepG2XRCC6
    CCDC88CENSG00000015133.14519.07670333.588200.637803.644702.42620HepG2XRCC6
    CHDHENSG00000016391.61657.136003117.69540-0.911809.619407.77720HepG2XRCC6
    GLT8D1ENSG00000016864.121104.525101653.75810-0.582304.076102.79430HepG2XRCC6
    ATP2C1ENSG00000017260.151125.445201660.84500-0.561403.845202.59490HepG2XRCC6
    SLC38A5ENSG00000017483.10517.080201122.33560-1.118005.951704.43370HepG2XRCC6
    WWTR1ENSG00000018408.101685.161502797.84250-0.731406.451504.88230HepG2XRCC6
    PHLDB1ENSG00000019144.12750.11980452.068400.730505.125103.70940HepG2XRCC6
    CYP24A1ENSG00000019186.5827.58110366.858401.1736011.677509.66750HepG2XRCC6
    CD74ENSG00000019582.102694.705701533.497600.813206.911105.29930HepG2XRCC6
    NCDNENSG00000020129.11297.69340167.965800.825602.944801.84960HepG2XRCC6
    C8BENSG00000021852.8125.62420396.84690-1.6595014.7800012.54690HepG2XRCC6
    BIRC3ENSG00000023445.9154.2252091.582600.751802.610101.58400HepG2XRCC6
    STRAPENSG00000023734.62256.989101539.983400.551403.832702.58410HepG2XRCC6
    ABCC2ENSG00000023839.65432.914408694.18080-0.678303.906502.64960HepG2XRCC6
    DEPDC1ENSG00000024526.12768.92670527.204500.544403.092001.96940HepG2XRCC6
    HSD17B6ENSG00000025423.721.4373054.95760-1.358203.077201.95800HepG2XRCC6
    TOMM34ENSG00000025772.71835.16400994.290800.884108.541706.78240HepG2XRCC6
    FASENSG00000026103.15636.95280206.024301.6283018.6146016.17930HepG2XRCC6
    RNASET2ENSG00000026297.111328.552603840.92820-1.5316025.1580022.45080HepG2XRCC6
    BTN3A1ENSG00000026950.12378.46420553.96790-0.549602.578101.55970HepG2XRCC6
    IFNGR1ENSG00000027697.82730.767402025.935200.430602.553701.53950HepG2XRCC6
    VRK2ENSG00000028116.12679.29200434.264000.645403.993702.72130HepG2XRCC6
    VEZTENSG00000028203.131297.24460965.537800.425902.291001.32880HepG2XRCC6
    TBPL1ENSG00000028839.5368.51690252.650100.544502.425801.43410HepG2XRCC6
    BAK1ENSG00000030110.8678.58150344.921100.976208.087006.36450HepG2XRCC6
    IKZF2ENSG00000030419.1269.8431033.015601.080902.658301.62510HepG2XRCC6
    SARSENSG00000031698.81945.934101414.593200.460002.796201.73640HepG2XRCC6
    FUT8ENSG00000033170.12917.98460492.286400.898907.599905.91840HepG2XRCC6
    TMSB10ENSG00000034510.46721.164504732.097900.506103.620802.40750HepG2XRCC6
    FAM136AENSG00000035141.32332.399201672.632900.479603.008801.90090HepG2XRCC6
    VCLENSG00000035403.121699.084201075.804200.659205.023903.62250HepG2XRCC6
    TIMP2ENSG00000035862.81945.403801416.448500.457702.788501.73040HepG2XRCC6
    USP2ENSG00000036672.11525.50300198.380901.4053013.6640011.51160HepG2XRCC6
    MFAP3ENSG00000037749.7486.71180886.93140-0.865806.099804.56310HepG2XRCC6
    VCANENSG00000038427.117553.970103204.063001.2372017.8552015.45850HepG2XRCC6
    CDH1ENSG00000039068.141596.372801095.789400.542703.529702.33180HepG2XRCC6
    C6ENSG00000039537.947.6953012.976101.877904.242702.94140HepG2XRCC6
    CDH10ENSG00000040731.617.025700.504505.076504.446403.11790HepG2XRCC6
    LSG1ENSG00000041802.6633.64710458.235900.467502.317201.34890HepG2XRCC6
    CAPGENSG00000042493.11141.6425063.133701.165704.875603.49160HepG2XRCC6
    PHKA2ENSG00000044446.71877.130303924.33470-1.0639013.0467010.94870HepG2XRCC6
    FAM214AENSG00000047346.8651.99960420.418000.632903.772102.53290HepG2XRCC6
    CPENSG00000047457.917736.7073041987.84330-1.243205.310203.86560HepG2XRCC6
    DTNBP1ENSG00000047579.15259.07740169.347400.613302.532301.52280HepG2XRCC6
    TSPAN17ENSG00000048140.13517.05760266.170800.957907.097105.46920HepG2XRCC6
    RRM2BENSG00000048392.72546.484401094.598901.2180015.7210013.45490HepG2XRCC6
    MRPS10ENSG00000048544.51128.62040827.928100.446902.422601.43200HepG2XRCC6
    R3HDM1ENSG00000048991.122319.937701528.473900.601904.444203.11610HepG2XRCC6
    Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

    *: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
    **: "-log(0)" was displayed as "99999.99999".





    118 RBPs can affect the gene expression of XRCC6 :

    Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
    XRCC6ENSG00000196419.85882.893907226.95860-0.296905.601804.54530HepG2AKAP8L
    XRCC6ENSG00000196419.89914.3869011829.52110-0.254804.689403.83670HepG2AUH
    XRCC6ENSG00000196419.84599.987506864.81280-0.577606.316205.02150HepG2BCLAF1
    XRCC6ENSG00000196419.86390.142208645.51200-0.436105.602504.78720HepG2BOP1
    XRCC6ENSG00000196419.86809.4520010997.35220-0.691507.275405.67720HepG2CCAR1
    XRCC6ENSG00000196419.85177.523307191.58930-0.4740018.3818016.99700HepG2CKAP4
    XRCC6ENSG00000196419.85542.822907937.00550-0.518006.927705.87840HepG2CPSF6
    XRCC6ENSG00000196419.89153.4737010906.35710-0.252803.736203.01220HepG2CELF1
    XRCC6ENSG00000196419.88574.3695011725.93360-0.4516018.0733016.48230HepG2DAZAP1
    XRCC6ENSG00000196419.87955.0599010113.10460-0.346302.896002.25810HepG2DDX3X
    XRCC6ENSG00000196419.84926.388907767.27340-0.656907.397806.20460HepG2DDX55
    XRCC6ENSG00000196419.86446.314808687.41070-0.430503.626602.92750HepG2DDX6
    XRCC6ENSG00000196419.85224.259906881.94060-0.397609.719308.60810HepG2DKC1
    XRCC6ENSG00000196419.83658.721306291.57080-0.7821027.1795025.23170HepG2DNAJC21
    XRCC6ENSG00000196419.84165.512006236.21790-0.5822025.8525024.05460HepG2DNAJC2
    XRCC6ENSG00000196419.83819.821905182.21220-0.440104.608003.17380HepG2EFTUD2
    XRCC6ENSG00000196419.85578.255808351.37440-0.582207.254606.32850HepG2EIF2S1
    XRCC6ENSG00000196419.87114.643209229.22890-0.375402.889502.23680HepG2EIF4A3
    XRCC6ENSG00000196419.86067.800908985.99060-0.566504.660303.78160HepG2EIF4B
    XRCC6ENSG00000196419.810284.2702011569.28200-0.169902.147101.39490HepG2EIF4G1
    XRCC6ENSG00000196419.87945.5152011082.46500-0.480106.087804.90070HepG2EIF4G2
    XRCC6ENSG00000196419.810141.9599013581.99950-0.4214012.2843011.16380HepG2ETF1
    XRCC6ENSG00000196419.86387.891008638.18360-0.435403.938603.15140HepG2G3BP1
    XRCC6ENSG00000196419.84802.564206988.88470-0.541306.179504.63550HepG2GNB2L1
    XRCC6ENSG00000196419.86409.517108997.08940-0.489204.990404.14680HepG2GPKOW
    XRCC6ENSG00000196419.86094.895606867.42290-0.172202.193601.31660HepG2HDGF
    XRCC6ENSG00000196419.84830.163406351.84800-0.395105.038404.20140HepG2HNRNPA1
    XRCC6ENSG00000196419.87880.2386010776.98890-0.4516012.1235010.42930HepG2HNRNPA2B1
    XRCC6ENSG00000196419.85401.925207065.32420-0.387304.707003.81880HepG2HNRNPC
    XRCC6ENSG00000196419.86474.404409162.15620-0.5009014.6303013.15210HepG2HNRNPF
    XRCC6ENSG00000196419.88854.2881010681.10100-0.270607.316206.26670HepG2HNRNPL
    XRCC6ENSG00000196419.85560.205308586.09940-0.626909.203008.12900HepG2HNRNPLL
    XRCC6ENSG00000196419.84324.238507018.60750-0.6987029.0107027.22640HepG2HNRNPU
    XRCC6ENSG00000196419.86351.006009022.15060-0.506509.315008.05680HepG2IGF2BP1
    XRCC6ENSG00000196419.86843.074108780.51270-0.359703.145602.43140HepG2IGF2BP2
    XRCC6ENSG00000196419.85146.823707169.26370-0.4781020.8784019.08230HepG2ILF2
    XRCC6ENSG00000196419.86563.697008831.71810-0.428203.044901.98550HepG2KHSRP
    XRCC6ENSG00000196419.85528.711306575.46130-0.250105.712104.26040HepG2KIF1C
    XRCC6ENSG00000196419.86836.0104011610.01750-0.764108.999407.49720HepG2LARP4
    XRCC6ENSG00000196419.87548.722309315.22140-0.303402.308201.70750HepG2MAGOH
    XRCC6ENSG00000196419.85804.162407004.19400-0.271102.486801.71800HepG2MSI2
    XRCC6ENSG00000196419.85610.293008756.97810-0.642405.506004.11060HepG2MTPAP
    XRCC6ENSG00000196419.87217.678209587.99190-0.409703.649502.92550HepG2NCBP2
    XRCC6ENSG00000196419.89016.4676011627.46930-0.366905.950104.83420HepG2NOL12
    XRCC6ENSG00000196419.86066.764608538.69260-0.493105.169604.19530HepG2PABPC4
    XRCC6ENSG00000196419.85888.282806947.13510-0.238603.833302.85380HepG2PARN
    XRCC6ENSG00000196419.87429.882708735.47050-0.233503.952503.25370HepG2PCBP1
    XRCC6ENSG00000196419.84841.165406260.02530-0.370806.617505.51550HepG2PPIL4
    XRCC6ENSG00000196419.84009.659205992.58860-0.579706.853905.64630HepG2PRPF8
    XRCC6ENSG00000196419.87119.243008888.82060-0.320306.487205.71820HepG2PTBP1
    XRCC6ENSG00000196419.89197.6632011099.73570-0.271201.949101.43650HepG2PUF60
    XRCC6ENSG00000196419.88842.7237011783.20890-0.4142016.7569015.55210HepG2PUM1
    XRCC6ENSG00000196419.88106.2898011774.38480-0.5385011.4883010.17230HepG2PUM2
    XRCC6ENSG00000196419.86925.238109626.48660-0.4751010.139909.04960HepG2QKI
    XRCC6ENSG00000196419.89727.1550011352.01190-0.222903.065102.52760HepG2RBM22
    XRCC6ENSG00000196419.87425.612608736.77840-0.234602.258501.64420HepG2RBM25
    XRCC6ENSG00000196419.86691.848208256.41540-0.303102.660601.68670HepG2RBM27
    XRCC6ENSG00000196419.88701.468109892.27700-0.185002.688902.15370HepG2NELFE
    XRCC6ENSG00000196419.88099.649409213.54180-0.185902.753002.13760HepG2RECQL
    XRCC6ENSG00000196419.86649.089609869.25410-0.569809.164608.03690HepG2RPLP0
    XRCC6ENSG00000196419.83502.635904910.13880-0.487307.470106.51960HepG2RPS19
    XRCC6ENSG00000196419.86036.615107614.60620-0.335003.170702.31330HepG2RPS2
    XRCC6ENSG00000196419.84085.308005927.98560-0.537105.259404.20830HepG2RRP9
    XRCC6ENSG00000196419.84874.916306250.34050-0.358609.687508.59610HepG2SAFB2
    XRCC6ENSG00000196419.83907.755604928.15790-0.334702.800601.85500HepG2SERBP1
    XRCC6ENSG00000196419.810864.848408006.441800.440303.292802.55530HepG2SF3A3
    XRCC6ENSG00000196419.86453.193508498.47020-0.397204.714803.81450HepG2SF3B1
    XRCC6ENSG00000196419.87156.442309254.13570-0.370909.369308.37950HepG2SF3B4
    XRCC6ENSG00000196419.88636.2140010643.63350-0.301508.224907.11290HepG2SLBP
    XRCC6ENSG00000196419.810941.9721012821.63320-0.228704.889504.27730HepG2SRFBP1
    XRCC6ENSG00000196419.812383.779309659.425900.3583010.429009.64110HepG2SRSF1
    XRCC6ENSG00000196419.86374.815609144.58820-0.520504.732803.39150HepG2SRSF3
    XRCC6ENSG00000196419.88970.0565010959.79090-0.289005.652304.80380HepG2SRSF5
    XRCC6ENSG00000196419.86076.478909001.36960-0.5669018.9714017.44370HepG2SRSF7
    XRCC6ENSG00000196419.86359.159007858.55380-0.305406.800806.00400HepG2SRSF9
    XRCC6ENSG00000196419.89337.6516011132.13200-0.253605.208604.54820HepG2SSB
    XRCC6ENSG00000196419.84494.112406406.25410-0.511403.381802.04450HepG2SUB1
    XRCC6ENSG00000196419.810129.0908012463.94310-0.299308.002907.03660HepG2SUCLG1
    XRCC6ENSG00000196419.86083.948108682.57880-0.5131012.8849011.80930HepG2TAF15
    XRCC6ENSG00000196419.85272.226708369.11940-0.6667011.4879010.16300HepG2TARDBP
    XRCC6ENSG00000196419.83903.216205182.90710-0.409103.545602.43410HepG2TFIP11
    XRCC6ENSG00000196419.85995.722107977.77800-0.412106.101604.86660HepG2TIA1
    XRCC6ENSG00000196419.84120.759206819.63460-0.7268019.3566018.25260HepG2TIAL1
    XRCC6ENSG00000196419.85168.503506880.86990-0.4128010.821409.81530HepG2TRIM56
    XRCC6ENSG00000196419.88549.5626010844.54230-0.343004.348003.22110HepG2TUFM
    XRCC6ENSG00000196419.88628.2980011479.15240-0.411903.673802.70260HepG2UBE2L3
    XRCC6ENSG00000196419.82664.561604567.93160-0.7776011.6895010.14610HepG2UCHL5
    XRCC6ENSG00000196419.86155.870107100.48910-0.206003.392402.63210HepG2UPF1
    XRCC6ENSG00000196419.81276.013907538.92780-2.5627066.1989062.43110HepG2XRCC6
    XRCC6ENSG00000196419.86129.035406909.80140-0.173002.938002.24900HepG2ZC3H8
    XRCC6ENSG00000196419.810296.7835012464.65930-0.275602.463301.31430K562ABCF1
    XRCC6ENSG00000196419.89649.811707928.267500.283405.914605.13400K562AGGF1
    XRCC6ENSG00000196419.89808.186208249.702900.249502.257501.66450K562AKAP8L
    XRCC6ENSG00000196419.89546.9037012745.21500-0.416905.102204.34810K562AQR
    XRCC6ENSG00000196419.86225.064207623.84160-0.292406.176604.71930K562BCLAF1
    XRCC6ENSG00000196419.86029.875608116.66290-0.428803.966402.91950K562BOP1
    XRCC6ENSG00000196419.82973.583903616.28090-0.282302.246901.31470K562CCAR1
    XRCC6ENSG00000196419.85926.565508630.56470-0.542307.968806.62070K562CPSF6
    XRCC6ENSG00000196419.85019.147805783.82000-0.204602.455501.46760K562CSTF2
    XRCC6ENSG00000196419.87147.423508291.16710-0.214202.840101.61230K562DDX21
    XRCC6ENSG00000196419.87799.1044010198.63800-0.387008.129206.99550K562EIF2S2
    XRCC6ENSG00000196419.813198.4707015509.04080-0.232703.186702.18080K562EIF4G2
    XRCC6ENSG00000196419.86707.931108780.96260-0.388503.798302.79170K562FMR1
    XRCC6ENSG00000196419.85646.263507442.47020-0.398503.798202.71240K562FTO
    XRCC6ENSG00000196419.87454.909806097.393500.289904.790404.02360K562FXR1
    XRCC6ENSG00000196419.86813.051808370.38970-0.297004.482703.03560K562GLRX3
    XRCC6ENSG00000196419.85538.343808240.24390-0.573209.081707.63310K562GPKOW
    XRCC6ENSG00000196419.810934.2025013591.03150-0.313803.810602.92820K562GRSF1
    XRCC6ENSG00000196419.84318.980907182.21890-0.7337016.8640015.46980K562HNRNPC
    XRCC6ENSG00000196419.85245.055406413.66550-0.290202.903001.73250K562HNRNPF
    XRCC6ENSG00000196419.810072.484407995.340300.333102.872501.61500K562HNRNPK
    XRCC6ENSG00000196419.89477.199307369.547500.362802.982802.01250K562HNRNPM
    XRCC6ENSG00000196419.88744.2460010341.20800-0.242003.151702.20070K562HNRNPU
    XRCC6ENSG00000196419.810434.705308755.062400.253102.346101.59540K562KIF1C
    XRCC6ENSG00000196419.84293.853807035.67250-0.712407.585105.95270K562KRR1
    XRCC6ENSG00000196419.85964.148008043.32220-0.431505.071003.86530K562METAP2
    XRCC6ENSG00000196419.86994.020408800.36180-0.331408.087406.77290K562MTPAP
    XRCC6ENSG00000196419.87964.718409778.05620-0.2959011.269909.90440K562NSUN2
    XRCC6ENSG00000196419.86903.306008411.40780-0.285102.100101.37510K562PCBP3
    XRCC6ENSG00000196419.85492.202106452.05190-0.232402.278801.55190K562POLR2G
    XRCC6ENSG00000196419.88456.588506206.336300.446205.367304.31980K562PRPF8
    XRCC6ENSG00000196419.84865.951906439.59350-0.404205.138403.85600K562PSIP1
    XRCC6ENSG00000196419.813595.2361017635.45150-0.375407.676306.05260K562PUM2
    XRCC6ENSG00000196419.811983.685108181.576500.550508.275607.38540K562PUS1
    XRCC6ENSG00000196419.810248.782507971.602000.362406.494505.61140K562RBM15
    XRCC6ENSG00000196419.84996.950705875.20740-0.233602.337301.43070K562RCC2
    XRCC6ENSG00000196419.84578.624105569.54860-0.282602.595101.61230K562SRFBP1
    XRCC6ENSG00000196419.88258.233909884.93540-0.259406.481805.11970K562SRPK2
    XRCC6ENSG00000196419.84563.671506009.12650-0.397003.359602.22920K562SUPV3L1
    XRCC6ENSG00000196419.87773.206706471.278700.264403.151202.27520K562SYNCRIP
    XRCC6ENSG00000196419.86239.073108110.10720-0.378403.788502.95460K562TARDBP
    XRCC6ENSG00000196419.86715.389807823.16820-0.220302.154001.43940K562TIA1
    XRCC6ENSG00000196419.84534.332606193.82250-0.449904.592803.36320K562TIAL1
    XRCC6ENSG00000196419.85221.337506580.03800-0.333703.485702.40200K562TRIM56
    XRCC6ENSG00000196419.84359.345406359.89460-0.544906.879005.19230K562UCHL5
    XRCC6ENSG00000196419.87877.7940010367.87530-0.3963011.4347010.09930K562UPF1
    XRCC6ENSG00000196419.87835.332209734.58370-0.313102.526601.38400K562UTP3
    XRCC6ENSG00000196419.86848.418508871.47170-0.373405.045903.84770K562WDR3
    XRCC6ENSG00000196419.8777.572706530.83680-3.0702054.8923050.52910K562XRCC6
    XRCC6ENSG00000196419.85126.001006476.10990-0.337302.911001.66460K562XRN2
    XRCC6ENSG00000196419.812005.0571014358.15250-0.258202.417901.61980K562ZC3H8
    Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

    *: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
    **: "-log(0)" was displayed as "99999.99999".





    889 alternative splicing events after Knockdown/Knockout XRCC6 protein :

    Only display 100 entries as example. Please click "View All" button to see all 889 entries.     

    Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
    SETMBIM1ENSG00000135926.8chr2-2191487612191488592191466622191469042191504852191506610.428000.000060.00939includedK562XRCC6
    SENT5DC2ENSG00000168268.6chr3-5256617852566418525631655256335052567521525677930.085000.000210.02475includedK562XRCC6
    SEPPIL2ENSG00000100023.13chr22+2202455222024665220242012202425122024854220249000.119000.000000.00000includedK562XRCC6
    SEIMMP1LENSG00000148950.5chr11-3150967431509788314990473149930631531065315311420.587000.000140.01786includedK562XRCC6
    SEANAPC10ENSG00000164162.8chr4-1460188391460189121460171361460172631460192711460193410.108000.000140.01764includedK562XRCC6
    SEAC079466.1ENSG00000266976.1chr19+2910116629101238290975942909801129103345291061360.070000.000040.00714includedK562XRCC6
    SESEPT9ENSG00000184640.13chr17+7549229575492469754890617548915875493396754934480.067000.000000.00000includedK562XRCC6
    SEKDM5BENSG00000117139.12chr1-2027355242027356322027331762027332732027360532027361880.094000.001260.09037includedK562XRCC6
    SEZNF791ENSG00000173875.9chr19+1272303912723179127217331272189612734513127346400.457000.000030.00505includedK562XRCC6
    SEUSMG5ENSG00000173915.8chr10-1051555021051557891051521381051522231051561651051561980.113000.000020.00366includedK562XRCC6
    SEXRCC2ENSG00000196584.2chr7-1523577851523578671523435881523464481523731251523732500.146000.000950.07381includedK562XRCC6
    SESELOENSG00000073169.9chr22+5064334750643453506394075064001950644745506449490.655000.000000.00096includedK562XRCC6
    SENEK7ENSG00000151414.10chr1+1981901281981902401981261231981264061982016821982017670.836000.000000.00103includedK562XRCC6
    SEKIAA1715ENSG00000144320.9chr2-1768004351768005181767939001767949271768020711768022420.075000.000130.01705includedK562XRCC6
    SENUPL1ENSG00000139496.11chr13+2587723925877293258757622587601825881943258820870.084000.001210.08813includedK562XRCC6
    SEZNF148ENSG00000163848.14chr3-1250337801250338971250321511250325001250421521250422880.391000.000110.01512includedK562XRCC6
    SEFTSJ2ENSG00000122687.13chr7-2277649227857222739292275199227905222793420.415000.000000.00002includedK562XRCC6
    SERNF34ENSG00000170633.12chr12+1218405441218406101218379211218380211218539611218541800.148000.000570.05098includedK562XRCC6
    SEUBP1ENSG00000153560.7chr3-3343793633438008334376533343777233438536334386270.089000.000780.06389includedK562XRCC6
    SECPNE7ENSG00000178773.10chr16+8966037389660566896575348965766889661774896620110.216000.000620.05452includedK562XRCC6
    SEMDC1ENSG00000137337.10chr6-3067534230676134306751603067523130679188306792810.279000.000020.00399includedK562XRCC6
    SETBX18ENSG00000112837.12chr6-8545215385452266854482148544830985453978854540430.126000.000440.04246includedK562XRCC6
    SEIVNS1ABPENSG00000116679.11chr1-1852756161852757571852746671852747751852761451852762710.113000.000140.01768includedK562XRCC6
    SEDPM1ENSG00000000419.8chr20-4955766549557746495574014955747049558567495586630.453000.000000.00000includedK562XRCC6
    SERBL2ENSG00000103479.10chr16+5348813753488259534876165348768153488567534887540.162000.000000.00000includedK562XRCC6
    SEKRT222ENSG00000264058.1chr17-3878645938786538387850483878524538786965387871760.053000.000000.00059includedK562XRCC6
    SEGPBP1ENSG00000062194.11chr5+5653293956532999565317925653185956542126565423110.198000.000730.06127includedK562XRCC6
    SEVRK2ENSG00000028116.12chr2+5838188858381937583734505837360958386483583870550.140000.001200.08736includedK562XRCC6
    SEHMMRENSG00000072571.15chr5+1628947061628947541628917281628918081628966461628968350.248000.000000.00130includedK562XRCC6
    SEDNAJC12ENSG00000108176.10chr10-6957579769575891695712816957142169583071695831500.091000.000000.00036includedK562XRCC6
    SEMYSM1ENSG00000162601.5chr1-5915496559155039591547095915478859155897591559210.266000.000510.04658includedK562XRCC6
    SEPRMT1ENSG00000126457.16chr19+5018312850183263501804295018057350183743501838450.108000.000030.00624includedK562XRCC6
    SEEIF4HENSG00000106682.10chr7+7360457673604636736041517360424873609070736092080.104000.000010.00197includedK562XRCC6
    SECOPZ1ENSG00000111481.5chr12+5473595054736071547343305473439954739243547392990.536000.000130.01710includedK562XRCC6
    SECCT4ENSG00000115484.10chr2-6211515862115392621121546211220762115515621157480.051000.000150.01923includedK562XRCC6
    SEC6orf48ENSG00000204387.8chr6+3180420031804294318031873180322831805012318052120.447000.000000.00000includedK562XRCC6
    SETRIM59ENSG00000213186.3chr3-1601665131601665831601566361601569741601675041601676170.268000.000010.00167includedK562XRCC6
    SECHEK1ENSG00000149554.8chr11+1255073431255074391255053231255054281255136861255138020.095000.000090.01241includedK562XRCC6
    SESREK1ENSG00000153914.11chr5+6545189265454760654492906544942465455046654551620.186000.001170.08597includedK562XRCC6
    SECOPS3ENSG00000141030.8chr17-1716491317165006171636871716378817165279171654420.215000.000000.00000includedK562XRCC6
    SEHPS1ENSG00000107521.14chr10-1001908871001910481001903271001904271001936961001938480.288000.000490.04564includedK562XRCC6
    SEWARS2ENSG00000116874.7chr1-1196672211196673061196191431196192301196831771196832710.169000.001020.07792includedK562XRCC6
    SETANKENSG00000136560.9chr2+1620177951620179231620168591620169971620361241620362720.140000.000280.03018includedK562XRCC6
    SERAB1AENSG00000138069.12chr2-6531811665318212653139886531582465325104653252000.051000.000050.00867includedK562XRCC6
    SERHOT1ENSG00000126858.12chr17+3049995530500079304980613049812030500849305009310.106000.000050.00847includedK562XRCC6
    SETOP3BENSG00000100038.15chr22-2233035222330559223300112233017922337126223371840.075000.000350.03595includedK562XRCC6
    SEHBE1ENSG00000213931.1chr11-5303138530318152910285291386552679855268340.141000.000110.01503includedK562XRCC6
    SEUBE2BENSG00000119048.3chr5+1337246671337247431337240151337241041337259151337260120.186000.000000.00000includedK562XRCC6
    SEHNRNPA2B1ENSG00000122566.16chr7-2623061226230748262297442623008026232114262321970.141000.000050.00802includedK562XRCC6
    SEHNRNPA2B1ENSG00000122566.16chr7-2623745026237486262372412623735226240191262403660.067000.000020.00397includedK562XRCC6
    SEBORAENSG00000136122.11chr13+7330541873305525733030637330323173309097733091430.241000.000820.06645includedK562XRCC6
    SELPIN3ENSG00000132793.7chr20+3996981939969949399695593996964239974435399746350.155000.001020.07792includedK562XRCC6
    SEEEDENSG00000074266.13chr11+8598112485981199859789368597960385988021859881800.171000.000180.02125includedK562XRCC6
    SEMORF4L2ENSG00000123562.12chrX-1029396081029396571029334261029335791029400981029401880.218000.000000.00000includedK562XRCC6
    SECLIC2ENSG00000155962.8chrX-1545080991545082191545072681545073531545084371545086190.106000.000000.00000includedK562XRCC6
    SECCDC101ENSG00000176476.4chr16+2859993028600012285969682859704128600420286004850.114000.000190.02297includedK562XRCC6
    SEFNBP4ENSG00000109920.8chr11-4774728847747388477460234774633047752925477531130.198000.000050.00903includedK562XRCC6
    SEARPP19ENSG00000128989.6chr15-5285638652856443528492965284941952861044528610990.132000.000000.00107includedK562XRCC6
    SENFYCENSG00000066136.15chr1+4117835841178493411575094115753941204507412046200.129000.000000.00052includedK562XRCC6
    SENFYCENSG00000066136.15chr1+4122903441229161412285594122871841232267412323590.096000.000080.01209includedK562XRCC6
    SESLC25A19ENSG00000125454.7chr17-7328299573283114732827277328288373284582732846720.292000.000580.05103includedK562XRCC6
    SEMYBENSG00000118513.14chr6+1355235511355238071355227761355228871355243541355244620.271000.000000.00000includedK562XRCC6
    SEMYBENSG00000118513.14chr6+1355206631355207191355200451355201881355212221355213370.068000.000050.00841includedK562XRCC6
    SETCERG1ENSG00000113649.7chr5+1458415801458416591458387771458389001458431131458433560.054000.000220.02556includedK562XRCC6
    SEMRPL10ENSG00000159111.8chr17-4590650445906602459058664590603645908825459089000.133000.000000.00000includedK562XRCC6
    SETMEM69ENSG00000159596.6chr1+4615664546156782461528854615394746158875461601150.073000.000000.00015includedK562XRCC6
    SEBCORENSG00000183337.12chrX-3993088939930943399302253993041239931601399344330.204000.000000.00000includedK562XRCC6
    SETMEM173ENSG00000184584.8chr5-1388610621388612891388607701388609271388617941388618950.137000.000630.05477includedK562XRCC6
    SEHNRNPDENSG00000138668.14chr4-8329268083292737832806238328079283294598832951390.145000.000000.00000includedK562XRCC6
    SECLINT1ENSG00000113282.9chr5-1572176071572176591572163701572165211572187101572188490.118000.000020.00379includedK562XRCC6
    SEELOVL6ENSG00000170522.5chr4-1110142611110142901109808001109809101110266521110267840.114000.000000.00085includedK562XRCC6
    SEVPRBPENSG00000145041.11chr3-5153074951530796515177345151785251533888515340100.625000.000480.04539includedK562XRCC6
    SECOPS8ENSG00000198612.6chr2+2379953742379954392379945242379946852379957692379958400.087000.000270.02972includedK562XRCC6
    SER3HDM1ENSG00000048991.12chr2+1363742371363743271363624251363625861363790631363791780.154000.000260.02904includedK562XRCC6
    SESUGP2ENSG00000064607.12chr19-1910444619104549191016961910195819105174191052950.165000.000070.01100includedK562XRCC6
    SECARS2ENSG00000134905.12chr13-1112964111112965291112946611112948681112967311112970280.510000.000130.01728includedK562XRCC6
    SENASPENSG00000132780.12chr1+4606605646066129460568944605694246067926460680370.076000.000020.00376includedK562XRCC6
    SESLC7A6ENSG00000103064.9chr16+6830772068307807683004956830062468308593683091520.287000.000070.01079includedK562XRCC6
    SEAKAP17AENSG00000197976.6chrX+1719030171910017180841718325171955117213950.247000.000500.04655includedK562XRCC6
    SECRYZENSG00000116791.9chr1-7519606575196104751903947519051875198639751990920.170000.000040.00758includedK562XRCC6
    SEMDM2ENSG00000135679.17chr12+6920940769209500692073336920740869210591692107250.307000.000010.00273includedK562XRCC6
    SEGALK2ENSG00000156958.10chr15+4961116849611313495845234958473449611800496120020.681000.000000.00000includedK562XRCC6
    SERP11-155D18.12ENSG00000254782.1chr3-5200582752005908520054755200571452007980520080470.192000.000860.06823includedK562XRCC6
    SEATP6V0A1ENSG00000033627.10chr17+4063094440631067406304804063060740632684406327350.138000.000000.00115includedK562XRCC6
    SERIF1ENSG00000080345.13chr2+1523255671523256211523251611523252701523262241523263780.059000.000980.07572includedK562XRCC6
    SESERPINH1ENSG00000149257.9chr11+7527477175274815752731007527336475277360752780160.172000.000400.03910includedK562XRCC6
    SECHMP2BENSG00000083937.4chr3+8728947287289603872764588727670687289848872899400.555000.000000.00002includedK562XRCC6
    SERP11-514P8.7ENSG00000270249.1chr7-1021851521021852231021819471021821091022074431022075300.374000.001330.09405includedK562XRCC6
    SEHNRNPCENSG00000092199.13chr14-2173182521731988217314692173149521737456217375650.090000.000000.00000includedK562XRCC6
    SEFRG1ENSG00000109536.7chr4+1908761911908763061908733161908734421908785521908786570.109000.000790.06452includedK562XRCC6
    SEABL1ENSG00000097007.13chr9+1337551041337551391337538011337539541337554541337555440.054000.000700.05954includedK562XRCC6
    SEDMTF1ENSG00000135164.14chr7+8679727286797359867957988679592186800310868003730.147000.000030.00547includedK562XRCC6
    SELGALS8ENSG00000116977.14chr1+2366887232366888452366872692366873612366892672366894150.052000.000000.00009includedK562XRCC6
    SEEXOC1ENSG00000090989.13chr4+5675505356755098567499885675009456756388567565520.218000.000120.01633includedK562XRCC6
    SESYPL1ENSG00000008282.3chr7-1057329931057331151057318521057323851057333941057335830.097000.000000.00036includedK562XRCC6
    SECREBZFENSG00000137504.9chr11-8537422285374337853729968537350185374567853746450.167000.000080.01209includedK562XRCC6
    SEDDX50ENSG00000107625.8chr10+7066598170666093706610727066122770666466706667630.230000.000000.00000includedK562XRCC6
    SEERCC8ENSG00000049167.9chr5-6022793360227975602246906022478660240758602409000.189000.000010.00155includedK562XRCC6
    SEUPF3AENSG00000169062.10chr13+1150517761150518751150474951150476021150519931150521040.200000.000010.00186includedK562XRCC6
    SEBAXENSG00000087088.15chr19+4946349549463593494594544945959049464066494641710.068000.001100.08232includedK562XRCC6





    10 RBPs can affect the splicing of XRCC6 :

    Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
    SEXRCC6ENSG00000196419.8chr22+4205288442052989420495324204969442054255420543560.607000.006470.05751includedK562AQR
    A3SSXRCC6ENSG00000196419.8chr22+420321164203225542032239420322554202412142024234-0.130000.000000.00000shorterK562SUPV3L1
    A3SSXRCC6ENSG00000196419.8chr22+420321164203225542032239420322554202412142024234-0.064000.000000.00004shorterHepG2U2AF2
    A3SSXRCC6ENSG00000196419.8chr22+4204669042046796420467264204679642042899420430860.083000.000000.00000longerK562AQR
    RIXRCC6ENSG00000196419.8chr22+4201735342018090420173534201741442017993420180900.525000.000530.08870includedHepG2XRCC6
    RIXRCC6ENSG00000196419.8chr22+4201735342018090420173534201741442017993420180900.606000.008890.07068includedK562AKAP8L
    RIXRCC6ENSG00000196419.8chr22+4201735342018090420173534201741442017993420180900.416000.001530.01323includedHepG2SF3B4
    RIXRCC6ENSG00000196419.8chr22+4201735342018090420173534201741442017993420180900.404000.001050.00704includedK562AQR
    MXEXRCC6ENSG00000196419.8chr22+42054255420543564205733442057448420529064205303642059625420600420.101000.000390.024481includedHepG2BCCIP
    MXEXRCC6ENSG00000196419.8chr22+42054255420543564205733442057448420529064205303642059625420600420.111000.000080.005511includedHepG2XRN2
    MXEXRCC6ENSG00000196419.8chr22+4204953242049694420529064205303642046726420468954205425542054356-0.087000.001980.052652includedHepG2XRN2
    MXEXRCC6ENSG00000196419.8chr22+42054255420543564205733442057448420529064205303642059625420600420.119000.000060.002771includedHepG2DDX55
    MXEXRCC6ENSG00000196419.8chr22+4202412142024234420321164203225542017993420180904203251942032774-0.167000.001090.008712includedHepG2U2AF2
    MXEXRCC6ENSG00000196419.8chr22+4202412142024234420321164203225542017993420180904203251942032774-0.091000.000040.001462includedK562HNRNPC

    *: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
    **: "-log(0)" was displayed as "99999.99999".





    The XRCC6 protein affects to its own RNA splicing after knockdown/knockout.

    Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
    RIXRCC6ENSG00000196419.8chr22+4201735342018090420173534201741442017993420180900.525000.000530.08870includedHepG2XRCC6