EIF4A3

General Information

Gene Name       : EIF4A3
Gene ID             : ENSG00000141543.10
Essential Gene : Yes

Functions

Localization(RBPImage: EIF4A3)

Domains (AlphaFold: EIF4A3)


Antibody Validation

 View validation images for all EIF4A3 antibodies

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878EIF4A3ENSG00000141543.1057.6466.8062.22ENCSR000AEF
HepG2EIF4A3ENSG00000141543.10161.68141.99151.84ENCSR985KAT
K562EIF4A3ENSG00000141543.1094.6685.4490.05ENCSR000AEO

Assays

4 Released experiments are available on ENCORE database.

Assay TypeExp_NameENCODE IDTarget labelBiosampleStatusLinked AntibodyControlsMethodNote
knockdown followed by RNA-seq EIF4A3-BGKLV08-K562ENCSR961YAGEIF4A3K562ReleasedENCSR913CAE   shRNAKD% = 29.4,39.0
knockdown followed by RNA-seq EIF4A3-BGHLV12-HepG2ENCSR957EEGEIF4A3HepG2ReleasedENCSR237YZT   shRNAKD% = 71.9,63.4
knockdown followed by RNA-seq EIF4A3-BGKcLV15-K562ENCSR264MSXEIF4A3K562ReleasedENCSR404OHQ   CRISPRKD% = 93.2,81.8
knockdown followed by RNA-seq EIF4A3-BGHcLV16-HepG2ENCSR999MAEEIF4A3HepG2ReleasedENCSR964HKT   CRISPRKD% = 51.5,56.1






  eCLIP  

No eCLIP experiment available



  Antibody Validation  
  GeneName    Antibody_DCC_ID    Product_ID    Lot_ID    Phosphate    HepG2 Primary Validation    K562 Primary Validation    HepG2 Secondary Validation    K562 Secondary Validation  
EIF4A3ENCAB574DGTA302-981A1Released, ENCODE3Released, ENCODE3BGHLV12-21, Released, ENCODE3BGKLV08-21, Released, ENCODE3
EIF4A3ENCAB214HYQPA5-54532TK2671524AReleased, ENCODE4BGHcLV16-25, Released, ENCODE4BGKcLV15-31, Released, ENCODE4


  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
EIF4A3K562shRNAENCSR961YAGENCSR913CAEEIF4A3-LV08-21,EIF4A3-LV08-22Nontarget-LV08-1_00003527,nontarget-LV08-2_0000352729.4,39.0ReleasedENCODE3
EIF4A3HepG2shRNAENCSR957EEGENCSR237YZTEIF4A3-BGHLV12-21,EIF4A3-BGHLV12-22NT-BGHLV12-01,NT-BGHLV12-0271.9,63.4ReleasedENCODE3
EIF4A3K562CRISPRBGKcLV15-29,BGKcLV15-30BGKcLV15-1,BGKcLV15-238.2,27.6NotSatisfiedENCODE4
EIF4A3K562CRISPRENCSR264MSXENCSR404OHQEIF4A3-BGKcLV15-31,EIF4A3-BGKcLV15-32NT-BGKcLV15-1,NT-BGKcLV15-293.2,81.8ReleasedENCODE4
EIF4A3HepG2CRISPRENCSR999MAEENCSR964HKTEIF4A3-BGHcLV16-25,EIF4A3-BGHcLV16-26NT-BGHcLV16-1,NT-BGHcLV16-251.5,56.1ReleasedENCODE4
EIF4A3HepG2CRISPRBGHcLV16-27,BGHcLV16-28BGHcLV16-1,BGHcLV16-217.5,37.9NotSatisfiedENCODE4


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  
    EIF4A3: Click to RBP Image Database
  • Nuclei
  • Nucleoplasm
  • Mutually Exclusive from Nucleolus
  • Cytoplasm
  • Compartment/Organelle
  • Cytosolic
  • Nuclear release mitosis












    • RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela
    EIF4A3Product_ID: A302-981A
    Lot_ID: 1
    Source: Bethyl Labs
    Target Name: EIF4A3-human    		 HepG2_Bethyl_A302-981A_1_EIF4A3.png<br>Caption: IP-Western Blot analysis of HepG2 whole cell lysate using EIF4A3 specific antibody. Lane 1 is 1% of twenty million whole cell lysate input and lane 2 is 25% of IP enrichment using rabbit normal IgG (lanes under 'IgG'). Lane 3 is 1% of twenty million whole cell lysate input and lane 4 is 10% IP enrichment using rabbit polyclonal anti-EIF4A3 antibody (lanes under 'EIF4A3').
    		 EIF4A3_Secondary_Western.png<br>Caption: Western blot following shRNA against EIF4A3 in K562 and HepG2 whole cell lysate using EIF4A3 specific antibody. Lane 1 is a ladder, lane 2 is K562 non-targeting control knockdown, lane 2 and 3 are two different shRNAs against EIF4A3. Lanes 5-7 follow the same pattern, but in HepG2. EIF4A3 protein appears as the green band, GAPDH serves as a control and appears in red.
    		 K562_Bethyl_A302-981A_1_EIF4A3.png<br>Caption: IP-Western Blot analysis of K562 whole cell lysate using EIF4A3 specific antibody. Lane 1 is 1% of twenty million whole cell lysate input and lane 2 is 25% of IP enrichment using rabbit normal IgG (lanes under 'IgG'). Lane 3 is 1% of twenty million whole cell lysate input and lane 4 is 10% IP enrichment using rabbit polyclonal anti-EIF4A3 antibody (lanes under 'EIF4A3').
    		 EIF4A3_Secondary_Western.png<br>Caption: Western blot following shRNA against EIF4A3 in K562 and HepG2 whole cell lysate using EIF4A3 specific antibody. Lane 1 is a ladder, lane 2 is K562 non-targeting control knockdown, lane 2 and 3 are two different shRNAs against EIF4A3. Lanes 5-7 follow the same pattern, but in HepG2. EIF4A3 protein appears as the green band, GAPDH serves as a control and appears in red.
    EIF4A3Product_ID: PA5-54532
    Lot_ID: TK2671524A
    Source: Thermo Fisher
    Target Name: EIF4A3-human    		 EIF4A3-HEPG2-CRISPR-PA5-54532.png<br>Caption: Western blot following CRISPR against EIF4A3 in HepG2 whole cell lysate using EIF4A3 specific antibody. Lane 1 is a ladder, lane 2 is HepG2 non-targeting control knockdown, lane 3 and 4 are two different CRISPR against EIF4A3. EIF4A3 protein appears as the green arrow, Beta-actin serves as a control and appears in red arrow.
    		 ThermoFisher_PA5-54532_TK2671524A_EIF4A3.png<br>Caption: IP-WB analysis of K562 whole cell lysate using the EIF4A3 specific antibody, PA5-54532. Lanes 1 and 3 are 2.5% of five million whole cell lysate input. Lanes 2 and 4 are 50% of IP enrichment from five million whole cell lysate using normal IgG antibody and the EIF4A3-specific antibody, PA5-54532. The same antibody was used to detect protein levels via Western blot. This antibody passes preliminary validation and will be further pursued for secondary validation. *NOTE* Protein sizes are taken from Genecards.org and are only estimates based on sequence. Actual protein size may differ based on protein characteristics and electrophoresis method used.
    		 EIF4A3-K562-CRISPR-PA5-54532.png<br>Caption: Western blot following CRISPR against EIF4A3 in K562 whole cell lysate using EIF4A3 specific antibody. Lane 1 is a ladder, lane 2 is K562 non-targeting control knockdown, lane 3 and 4 are two different CRISPR against EIF4A3. EIF4A3 protein appears as the green arrow, Beta-actin serves as a control and appears in red arrow.








    RNA Targets

    • eCLIP assay for EIF4A3 is not avaliable on ENCORE database.



    Proteins bound to RNA
    • EIF4A3 RNA is bound by 20 proteins.  







    eCLIP assay for EIF4A3 is not avaliable on ENCORE database.





    20 proteins are bound to EIF4A3 RNA:

    Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
    chr177810913878109289-3'-UTR,intron-Distal5.7618516.64724HepG2SUB1
    chr177810913378109219-3'-UTR,intron-Distal3.668369.42357HepG2LARP4
    chr177810914878109242-3'-UTR,intron-Distal4.330704.73230K562NOLC1
    chr177810922278109306-3'-UTR,CDS,intron-Distal3.551603.01092HepG2LIN28B
    chr177810925078109310-3'-UTR,CDS,intron-Distal3.344633.99381K562BUD13
    chr177810905078109208-3'-UTR,intron-Distal,intron-Proximal,polyA_site3.6620912.21651K562PABPC4
    chr177810923178109301-3'-UTR,CDS,intron-Distal3.369395.54091HepG2LARP4
    chr177810922978109306-3'-UTR,CDS,intron-Distal4.440433.47885K562LIN28B
    chr177810924078109280-3'-UTR,intron-Distal3.120623.87559K562YBX3
    chr177810924278109300-3'-UTR,CDS,intron-Distal3.170633.50786HepG2G3BP1
    chr177810906278109196-3'-UTR,intron-Distal,intron-Proximal,polyA_site4.0260336.29394K562PUM2
    chr177812070378120768-5'-UTR,CDS,intron-Distal3.492803.77614HepG2G3BP1
    chr177812076378120862-5'-UTR,intron-Distal3.308863.85127HepG2GRWD1
    chr177812056678120594-CDS,intron-Distal4.552628.01338K562AQR
    chr177811508278115168-CDS,intron-Distal,intron-Proximal3.700765.00154HepG2AQR
    chr177811511678115168-CDS,intron-Distal,intron-Proximal3.211444.96885HepG2G3BP1
    chr177811002678110062-CDS,intron-Distal,intron-Proximal6.8663842.39871K562PUM2
    chr177811793578117975-CDS,intron-Distal,intron-Proximal4.619064.68690HepG2PRPF8
    chr177810984578109931-CDS,intron-Distal,intron-Proximal3.266764.22050HepG2LARP4
    chr177812058678120700-CDS,intron-Distal3.6440312.30450HepG2GRWD1
    chr177812059278120683-CDS,intron-Distal3.831787.79455K562UCHL5
    chr177811798878118091-CDS,intron-Distal,intron-Proximal3.604397.62845K562SF3B4
    chr177812057478120593-CDS,intron-Distal4.152283.25089HepG2AQR
    chr177810986278109929-CDS,intron-Distal,intron-Proximal4.545155.50717HepG2G3BP1
    chr177810984178109882-CDS,intron-Distal7.3049519.47784K562PUM2
    chr177810980178109857-CDS,intron-Distal,intron-Proximal3.696114.63912HepG2LIN28B
    chr177811200378112066-CDS,intron-Distal4.034624.21087HepG2GRWD1
    chr177811511078115177-CDS,intron-Distal,intron-Proximal3.335937.09278HepG2PPIG
    chr177811005978110125-CDS,intron-Distal,intron-Proximal3.895375.69815HepG2G3BP1
    chr177811381378113940-CDS,intron-Distal,intron-Proximal4.1503710.16625HepG2G3BP1
    chr177811562378115695-CDS,intron-Distal,intron-Proximal4.215595.63851K562SF3B4
    chr177811546978115606-CDS,intron-Distal,intron-Proximal3.6122310.93931K562KHSRP
    chr177810988178109961-CDS,intron-Distal,intron-Proximal5.493207.36555K562SF3B4
    chr177810988278109931-CDS,intron-Distal,intron-Proximal6.4915677.22778K562PUM2
    chr177812069078120753-CDS,intron-Distal5.859737.43791K562RPS3
    chr177811557178115643-CDS,intron-Distal,intron-Proximal4.359804.45558HepG2GRWD1
    chr177810989878109989-CDS,intron-Distal,intron-Proximal4.376855.32062K562EFTUD2
    chr177810981078109868-CDS,intron-Distal3.867993.08171K562APOBEC3C
    chr177811561578115643-CDS,intron-Distal3.111726.58907K562YBX3
    chr177811118378111293-CDS,intron-Distal,intron-Proximal5.258068.37059HepG2G3BP1
    chr177810980078109865-CDS,intron-Distal,intron-Proximal4.765725.44291K562LIN28B
    chr177811201478112100-CDS,intron-Distal,intron-Proximal3.220364.56061K562BUD13
    chr177811194178112070-CDS,intron-Distal3.211865.11011HepG2G3BP1
    chr177811796678118044-CDS,intron-Distal,intron-Proximal3.568953.39306HepG2GRWD1
    chr177811564378115647-CDS,intron-Distal3.268365.74118K562YBX3
    chr177811112778111204-CDS,intron-Distal,intron-Proximal3.450553.98203HepG2PRPF8
    chr177810976278109815-CDS,intron-Distal,intron-Proximal4.173334.45914HepG2PRPF8
    chr177812059178120690-CDS,intron-Distal3.323067.18951HepG2G3BP1
    chr177812054078120636-CDS,intron-Distal4.1035611.94131HepG2PRPF8
    chr177811201078112068-CDS,intron-Distal3.616744.52024HepG2PPIG
    chr177811003078110112-CDS,intron-Distal4.170274.21087HepG2GRWD1
    chr177811554878115600-CDS,intron-Distal,intron-Proximal4.131423.31283K562PRPF8
    chr177811557578115616-CDS,intron-Distal,intron-Proximal4.043453.16051HepG2PPIG
    chr177811193878112076-CDS,intron-Distal,intron-Proximal4.162523.86058K562GRWD1
    chr177811378078113855-CDS,intron-Distal,intron-Proximal3.845499.77953HepG2PRPF8
    chr177811222578112345-intron-Distal3.793723.02234K562KHSRP
    chr177811534678115397-intron-Distal,intron-Proximal3.622363.55754HepG2U2AF2
    chr177811526878115383-intron-Distal,intron-Proximal4.910308.14619K562KHSRP
    chr177812052278120555-intron-Distal4.527318.01338K562AQR
    chr177811565078115704-intron-Distal,intron-Proximal4.413704.82767HepG2SF3B4
    chr177812053878120574-intron-Distal4.235954.27476HepG2AQR
    ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




    eCLIP assay for EIF4A3 is not avaliable on ENCORE database.



    Diffrential Expression
    • 11,983 differentially expressed genes after Knockdown/Knockout EIF4A3 protein.  





    • 106 RBPs can affect the levels of EIF4A3.  







    11,983 differentially expressed genes after Knockdown/Knockout EIF4A3 protein :

    Only display 100 entries as example. Please click "View All" button to see all 11,983 entries.     

    Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
    DPM1ENSG00000000419.81810.336802301.49910-0.346302.237001.66030HepG2EIF4A3
    SCYL3ENSG00000000457.9304.01370112.134101.4388011.4366010.16390HepG2EIF4A3
    C1orf112ENSG00000000460.12170.39640280.79750-0.720603.652602.92050HepG2EIF4A3
    NIPAL3ENSG00000001461.12608.08520399.328500.606603.992503.22810HepG2EIF4A3
    SEMA3FENSG00000001617.7217.39130524.82190-1.271505.727104.80830HepG2EIF4A3
    CYP51A1ENSG00000001630.1110207.9879014082.57860-0.464204.166903.38690HepG2EIF4A3
    KRIT1ENSG00000001631.10883.45310678.944900.379802.179001.60840HepG2EIF4A3
    RAD52ENSG00000002016.12348.02550209.868900.729604.241903.45450HepG2EIF4A3
    LAP3ENSG00000002549.81354.106502167.08980-0.678406.971705.95700HepG2EIF4A3
    LASP1ENSG00000002834.139888.997007423.790300.413603.346602.64470HepG2EIF4A3
    CASP10ENSG00000003400.10694.164801116.28510-0.685405.993905.05600HepG2EIF4A3
    CFLARENSG00000003402.152814.974302031.774900.470303.912803.15640HepG2EIF4A3
    TFPIENSG00000003436.108833.7731021702.07950-1.2967024.5330022.67940HepG2EIF4A3
    RBM5ENSG00000003756.123198.639402295.537300.478504.101603.32710HepG2EIF4A3
    SLC7A2ENSG00000003989.123662.7337013734.65410-1.9068054.7256051.97650HepG2EIF4A3
    ARF5ENSG00000004059.61752.860601403.512900.320601.845801.31930HepG2EIF4A3
    SARM1ENSG00000004139.985.7871013.817002.6342010.272009.05820HepG2EIF4A3
    PLXND1ENSG00000004399.8552.833801818.02520-1.717505.536204.63280HepG2EIF4A3
    AK2ENSG00000004455.122239.680504079.77170-0.8652011.7924010.50110HepG2EIF4A3
    FKBP4ENSG00000004478.51048.399102036.32280-0.9578012.7599011.41440HepG2EIF4A3
    KDM1AENSG00000004487.111949.504703577.48900-0.8758011.8522010.55810HepG2EIF4A3
    CCDC132ENSG00000004766.11529.66150388.467300.447202.402301.80570HepG2EIF4A3
    ARHGAP33ENSG00000004777.14227.30300109.079701.059104.068103.29690HepG2EIF4A3
    NDUFAB1ENSG00000004779.51557.821602249.16430-0.529904.569803.75170HepG2EIF4A3
    ZMYND10ENSG00000004838.930.766704.774902.687704.238503.45140HepG2EIF4A3
    HCCSENSG00000004961.10239.70900341.37260-0.510102.275001.69310HepG2EIF4A3
    SKAP2ENSG00000005020.8818.94050602.661000.442302.716802.08340HepG2EIF4A3
    SLC25A5ENSG00000005022.53703.3122010587.53320-1.5155035.9192033.66040HepG2EIF4A3
    LIG3ENSG00000005156.7438.97440770.41650-0.811507.322006.28250HepG2EIF4A3
    ACSM3ENSG00000005187.7796.380301622.83720-1.027005.056904.19600HepG2EIF4A3
    FAM214BENSG00000005238.15285.25270193.832700.557302.500001.89110HepG2EIF4A3
    CREBBPENSG00000005339.82361.877301601.450800.560504.932404.08270HepG2EIF4A3
    PON1ENSG00000005421.468.0462026.110601.381803.637402.90650HepG2EIF4A3
    GCFC2ENSG00000005436.9636.25750903.44180-0.505803.332902.63270HepG2EIF4A3
    WDR54ENSG00000005448.1223.66490216.02030-3.1903028.6467026.62210HepG2EIF4A3
    CROTENSG00000005469.7671.68170309.495601.1178011.8559010.56010HepG2EIF4A3
    ABCB4ENSG00000005471.11701.312801157.52400-0.722906.706705.70940HepG2EIF4A3
    MYCBP2ENSG00000005810.131655.699001100.682300.588905.230004.35220HepG2EIF4A3
    ITGALENSG00000005844.13362.33290258.814500.485302.271101.68960HepG2EIF4A3
    ZFXENSG00000005889.112705.526101841.610400.554805.171604.29940HepG2EIF4A3
    LAMP2ENSG00000005893.114879.574006026.97810-0.304701.984101.43980HepG2EIF4A3
    GDE1ENSG00000006007.71877.078102551.13940-0.442703.339002.63800HepG2EIF4A3
    C19orf60ENSG00000006015.13160.1537056.931101.492107.848606.77420HepG2EIF4A3
    CRLF1ENSG00000006016.6884.484803533.04370-1.998004.413003.60930HepG2EIF4A3
    OSBPL7ENSG00000006025.7447.88530142.586201.6512017.9841016.36500HepG2EIF4A3
    TMEM98ENSG00000006042.72107.025502744.91630-0.381602.682602.05350HepG2EIF4A3
    MAP3K14ENSG00000006062.9185.41220109.063000.765502.993602.32840HepG2EIF4A3
    SYNRGENSG00000006114.111353.12100830.883800.703505.590704.68270HepG2EIF4A3
    AP2B1ENSG00000006125.124175.328005963.33190-0.514204.747003.91320HepG2EIF4A3
    CX3CL1ENSG00000006210.67024.991603800.257400.8863012.7578011.41260HepG2EIF4A3
    SPATA20ENSG00000006282.15662.843901350.56600-1.026805.954205.01910HepG2EIF4A3
    TNFRSF12AENSG00000006327.9862.45570584.046500.562303.943203.18450HepG2EIF4A3
    JHDM1DENSG00000006459.6660.876902111.15760-1.6756034.5867032.36840HepG2EIF4A3
    FARP2ENSG00000006607.91396.189801096.195600.348902.064001.50950HepG2EIF4A3
    GGCTENSG00000006625.13436.57250569.79260-0.384201.882601.35120HepG2EIF4A3
    DBF4ENSG00000006634.3255.49460440.48390-0.785805.459204.56240HepG2EIF4A3
    GTF2IRD1ENSG00000006704.6401.49860745.75500-0.893308.307307.20310HepG2EIF4A3
    ARHGAP44ENSG00000006740.1263.95060112.42050-0.813902.469901.86450HepG2EIF4A3
    ELAC2ENSG00000006744.141120.62170809.516500.469103.135402.45620HepG2EIF4A3
    PNPLA4ENSG00000006757.7555.85150363.682900.611903.941303.18270HepG2EIF4A3
    ADIPOR2ENSG00000006831.94323.079606770.40610-0.647207.224906.19240HepG2EIF4A3
    MARK4ENSG00000007047.10545.566501075.65590-0.979408.338907.23230HepG2EIF4A3
    PROM1ENSG00000007062.7372.52950655.39000-0.815006.679605.68440HepG2EIF4A3
    KIAA0100ENSG00000007202.102629.543003539.13320-0.428603.345802.64410HepG2EIF4A3
    SLC13A2ENSG00000007216.1044.558300.548706.3433011.8010010.50940HepG2EIF4A3
    GAS7ENSG00000007237.1421.4401062.21380-1.536904.000103.23510HepG2EIF4A3
    RPUSD1ENSG00000007376.3262.13830164.790500.669601.885201.35340HepG2EIF4A3
    RHBDF1ENSG00000007384.11202.22550117.392600.784503.264802.57240HepG2EIF4A3
    LUC7LENSG00000007392.12751.937501016.47980-0.434902.695702.06460HepG2EIF4A3
    DNAJC11ENSG00000007923.111792.253301349.014900.409802.821502.17600HepG2EIF4A3
    MYLIPENSG00000007944.10222.76480115.835800.943304.843104.00100HepG2EIF4A3
    CDKL5ENSG00000008086.6113.9017059.494300.936903.071602.39880HepG2EIF4A3
    CDK11AENSG00000008128.18654.47190426.553300.617504.212003.42810HepG2EIF4A3
    DLEC1ENSG00000008226.1535.289502.195004.006906.427905.45290HepG2EIF4A3
    ADAM22ENSG00000008277.10384.65440237.527200.695403.329102.62910HepG2EIF4A3
    SYPL1ENSG00000008282.31405.308502190.47170-0.640406.252305.29740HepG2EIF4A3
    SPAG9ENSG00000008294.164062.939005181.25230-0.350802.420701.82150HepG2EIF4A3
    SS18L2ENSG00000008324.6202.69510281.05970-0.471601.870401.34090HepG2EIF4A3
    MPNDENSG00000008382.11428.82020303.600700.498102.000101.45380HepG2EIF4A3
    MGST1ENSG00000008394.81177.474302651.10440-1.1709019.1298017.46820HepG2EIF4A3
    CRY1ENSG00000008405.7306.90060451.61490-0.557303.028602.36030HepG2EIF4A3
    NFIXENSG00000008441.12269.12070404.38240-0.587503.219502.53080HepG2EIF4A3
    ST3GAL1ENSG00000008513.101515.110802761.09550-0.8658011.169509.91400HepG2EIF4A3
    MAPK8IP2ENSG00000008735.10326.85490101.855001.6820015.2535013.76910HepG2EIF4A3
    HEATR5BENSG00000008869.71357.24350689.331700.9773011.9719010.66700HepG2EIF4A3
    SEC62ENSG00000008952.123010.467503929.80690-0.384502.537501.92440HepG2EIF4A3
    RPS20ENSG00000008988.59374.3162014516.13250-0.630907.132306.10670HepG2EIF4A3
    CSDE1ENSG00000009307.116586.9754014699.54200-1.1581021.9569020.19970HepG2EIF4A3
    REV3LENSG00000009413.111853.936701071.327700.791108.900207.75840HepG2EIF4A3
    MASP2ENSG00000009724.12664.95330305.049801.1241011.5460010.26720HepG2EIF4A3
    FAM76AENSG00000009780.11258.06970157.565800.711703.369802.66600HepG2EIF4A3
    VTA1ENSG00000009844.111738.610802347.93900-0.433503.185602.50020HepG2EIF4A3
    MLXIPLENSG00000009950.117259.600003271.218001.1500012.3995011.07610HepG2EIF4A3
    RANBP9ENSG00000010017.9985.537801880.14090-0.9319011.8985010.59840HepG2EIF4A3
    SPRTNENSG00000010072.11224.65090147.794600.604002.407701.81000HepG2EIF4A3
    METTL13ENSG00000010165.15747.51090576.369900.375001.972401.42910HepG2EIF4A3
    UQCRC1ENSG00000010256.64546.414106030.59510-0.407603.281302.58690HepG2EIF4A3
    CD9ENSG00000010278.7189.64240512.89490-1.4354015.9186014.39940HepG2EIF4A3
    NCAPD2ENSG00000010292.82658.677603408.60600-0.358502.503301.89430HepG2EIF4A3
    IFFO1ENSG00000010295.15552.71440359.646400.619903.899203.14460HepG2EIF4A3
    Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

    *: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
    **: "-log(0)" was displayed as "99999.99999".





    106 RBPs can affect the gene expression of EIF4A3 :

    Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
    EIF4A3ENSG00000141543.5982.928501399.55190-0.509804.178803.03670HepG2ABCF1
    EIF4A3ENSG00000141543.53391.381402355.385500.525804.653503.98620HepG2AKAP1
    EIF4A3ENSG00000141543.51501.164201760.53740-0.229902.427401.70340HepG2AKAP8L
    EIF4A3ENSG00000141543.5766.322001948.84490-1.3466026.7623024.69860HepG2ASCC1
    EIF4A3ENSG00000141543.51076.984001686.36740-0.646906.560605.24060HepG2BCLAF1
    EIF4A3ENSG00000141543.5724.02050890.26380-0.298201.871401.37100HepG2BOP1
    EIF4A3ENSG00000141543.5828.703901131.41730-0.449204.651703.68290HepG2CALR
    EIF4A3ENSG00000141543.5942.292501851.54940-0.9745015.3787013.72800HepG2CIRBP
    EIF4A3ENSG00000141543.53111.178902733.542400.186602.173901.59330HepG2CELF1
    EIF4A3ENSG00000141543.52260.415202938.88380-0.378707.476906.34350HepG2DAZAP1
    EIF4A3ENSG00000141543.51210.698001908.20920-0.656406.478505.35370HepG2DDX55
    EIF4A3ENSG00000141543.53201.299001938.317000.723808.152907.14390HepG2DDX6
    EIF4A3ENSG00000141543.51442.519101676.59290-0.216902.154401.54480HepG2DKC1
    EIF4A3ENSG00000141543.51111.435301310.74700-0.238002.052801.43680HepG2DNAJC21
    EIF4A3ENSG00000141543.51283.551101863.15610-0.537605.165504.36930HepG2EIF2S1
    EIF4A3ENSG00000141543.5801.309701022.00560-0.351002.131601.32940HepG2EIF3D
    EIF4A3ENSG00000141543.5508.506402058.91220-2.0175047.8098045.24010HepG2EIF4A3
    EIF4A3ENSG00000141543.51816.934402777.66100-0.612407.965706.61580HepG2EIF4G2
    EIF4A3ENSG00000141543.52876.127803365.25570-0.226602.934902.31910HepG2ETF1
    EIF4A3ENSG00000141543.51253.527801712.29800-0.449905.107103.97480HepG2EWSR1
    EIF4A3ENSG00000141543.5966.228701219.29660-0.335602.707601.92920HepG2FUBP3
    EIF4A3ENSG00000141543.51197.388301748.32810-0.546103.660102.37870HepG2FUS
    EIF4A3ENSG00000141543.51436.188901927.16710-0.424203.264402.54530HepG2G3BP1
    EIF4A3ENSG00000141543.51617.025802046.13110-0.339602.510201.66450HepG2G3BP2
    EIF4A3ENSG00000141543.5601.33790926.39910-0.623505.087404.23610HepG2GPKOW
    EIF4A3ENSG00000141543.51041.686301676.30790-0.686404.198502.45650HepG2HLTF
    EIF4A3ENSG00000141543.51078.238001323.30270-0.295501.952401.39820HepG2HNRNPA1
    EIF4A3ENSG00000141543.52201.761702701.08500-0.294903.840802.76620HepG2HNRNPA2B1
    EIF4A3ENSG00000141543.51015.628901471.88140-0.535304.975404.06560HepG2HNRNPC
    EIF4A3ENSG00000141543.51211.423401781.05320-0.556007.770906.64850HepG2HNRNPF
    EIF4A3ENSG00000141543.5528.04490884.08530-0.743507.485506.50850HepG2HNRNPLL
    EIF4A3ENSG00000141543.51165.653201753.81340-0.589409.341708.08280HepG2IGF2BP1
    EIF4A3ENSG00000141543.51301.635701958.86980-0.589706.171005.19970HepG2IGF2BP2
    EIF4A3ENSG00000141543.51191.611701493.54990-0.325804.033703.16550HepG2ILF2
    EIF4A3ENSG00000141543.5561.52300901.78540-0.683404.173502.96830HepG2MTPAP
    EIF4A3ENSG00000141543.52286.124402914.20960-0.350204.341503.38700HepG2NOL12
    EIF4A3ENSG00000141543.51171.996801752.29660-0.580302.918601.79370HepG2NONO
    EIF4A3ENSG00000141543.5565.55640783.95500-0.471103.326802.50610HepG2NSUN2
    EIF4A3ENSG00000141543.51666.405101210.419900.461102.156301.38740HepG2PABPC1
    EIF4A3ENSG00000141543.51347.230501904.87600-0.499704.462503.55850HepG2PABPC4
    EIF4A3ENSG00000141543.5978.901301304.13280-0.413905.126504.15140HepG2PPIL4
    EIF4A3ENSG00000141543.5928.331101103.38000-0.249202.197701.50110HepG2PRPF4
    EIF4A3ENSG00000141543.5966.044401471.96390-0.607606.027804.88710HepG2PRPF8
    EIF4A3ENSG00000141543.51661.144102003.42770-0.270303.467002.86960HepG2PTBP1
    EIF4A3ENSG00000141543.51972.519502781.96380-0.496105.210304.42430HepG2PUF60
    EIF4A3ENSG00000141543.52405.234102951.06260-0.295102.296001.68280HepG2PUM2
    EIF4A3ENSG00000141543.51795.512802169.83730-0.273202.873002.23930HepG2QKI
    EIF4A3ENSG00000141543.51246.809501480.93510-0.248302.067401.31240HepG2RBM15
    EIF4A3ENSG00000141543.51794.517102812.73400-0.6484015.2632014.24600HepG2RBM22
    EIF4A3ENSG00000141543.51416.616901969.23820-0.475205.957905.00230HepG2RBM25
    EIF4A3ENSG00000141543.51232.308201620.46820-0.395002.984101.88180HepG2RCC2
    EIF4A3ENSG00000141543.51715.193802076.56440-0.275803.606402.91580HepG2RECQL
    EIF4A3ENSG00000141543.5888.153001918.86470-1.1114023.9038022.31390HepG2RPLP0
    EIF4A3ENSG00000141543.51055.037201568.97720-0.572503.602902.52590HepG2RPS10
    EIF4A3ENSG00000141543.5625.03340994.51220-0.670108.317107.31770HepG2RPS19
    EIF4A3ENSG00000141543.51119.697901456.07060-0.379002.447801.70400HepG2RRP9
    EIF4A3ENSG00000141543.51120.985601302.14100-0.216102.158201.57690HepG2SAFB2
    EIF4A3ENSG00000141543.5755.96570998.05970-0.400802.876301.91800HepG2SERBP1
    EIF4A3ENSG00000141543.51804.319901240.087700.540902.663202.00190HepG2SF3A3
    EIF4A3ENSG00000141543.51497.887502085.89050-0.477709.221208.23890HepG2SF3B4
    EIF4A3ENSG00000141543.51883.009302667.69950-0.5026013.1405011.80590HepG2SLBP
    EIF4A3ENSG00000141543.52752.538003176.88470-0.206902.669802.17440HepG2SRFBP1
    EIF4A3ENSG00000141543.52233.961302746.91830-0.298204.142603.40580HepG2SRSF5
    EIF4A3ENSG00000141543.51214.512701749.88000-0.5269010.837109.61520HepG2SRSF7
    EIF4A3ENSG00000141543.52547.718103123.88790-0.294105.156204.35210HepG2SUCLG1
    EIF4A3ENSG00000141543.5559.85340954.06610-0.7690010.729308.98940HepG2SUPT6H
    EIF4A3ENSG00000141543.5320.797201899.57390-2.5659074.4951072.06660HepG2SUPV3L1
    EIF4A3ENSG00000141543.51589.528801956.87300-0.300003.539702.91920HepG2TAF15
    EIF4A3ENSG00000141543.5654.65880861.87110-0.396702.780602.05490HepG2TARDBP
    EIF4A3ENSG00000141543.5925.976001273.20630-0.459403.303202.21970HepG2TFIP11
    EIF4A3ENSG00000141543.51468.484601798.17620-0.292202.698301.87180HepG2TIA1
    EIF4A3ENSG00000141543.5964.868001420.93650-0.558405.778105.10610HepG2TIAL1
    EIF4A3ENSG00000141543.51160.367901433.44450-0.304903.704703.07280HepG2TRIM56
    EIF4A3ENSG00000141543.52131.336402718.04370-0.350803.643202.62580HepG2TUFM
    EIF4A3ENSG00000141543.52286.896402877.12680-0.331202.118101.39180HepG2UBE2L3
    EIF4A3ENSG00000141543.5744.916401122.12380-0.591105.543604.46170HepG2UCHL5
    EIF4A3ENSG00000141543.5920.885301099.76880-0.256102.390501.73390HepG2UPF1
    EIF4A3ENSG00000141543.51565.536301061.782700.5601011.017009.94940HepG2UTP3
    EIF4A3ENSG00000141543.5926.955101088.91300-0.232302.235001.62230HepG2ZC3H8
    EIF4A3ENSG00000141543.51052.155401595.76830-0.600904.510602.82420HepG2ZRANB2
    EIF4A3ENSG00000141543.52494.712301175.658401.0853043.3675041.16240K562AGGF1
    EIF4A3ENSG00000141543.51619.329201291.855000.325902.704201.73660K562AKAP8
    EIF4A3ENSG00000141543.52296.856801223.322000.9088016.9082015.03510K562AKAP8L
    EIF4A3ENSG00000141543.51031.822601464.25150-0.505004.487801.80880K562ASCC1
    EIF4A3ENSG00000141543.51547.849801283.551800.270002.579301.69940K562ATP5C1
    EIF4A3ENSG00000141543.51609.971602004.57650-0.316304.534403.28790K562BCLAF1
    EIF4A3ENSG00000141543.5640.59890841.87630-0.394202.579801.73920K562BOP1
    EIF4A3ENSG00000141543.5527.14690778.31170-0.562104.808003.33270K562CCAR1
    EIF4A3ENSG00000141543.51405.121302075.65770-0.562906.949904.98770K562CIRBP
    EIF4A3ENSG00000141543.51177.112201708.06270-0.537102.515501.51190K562CNOT7
    EIF4A3ENSG00000141543.5683.50500895.12770-0.389103.063102.23920K562CPSF6
    EIF4A3ENSG00000141543.5650.25180871.27690-0.422103.025401.63510K562DHX30
    EIF4A3ENSG00000141543.51710.936301316.406600.378105.040403.80660K562DKC1
    EIF4A3ENSG00000141543.51913.581202550.65960-0.414606.895905.83540K562EIF2S2
    EIF4A3ENSG00000141543.5477.51100791.69460-0.729404.406503.10890K562EIF3A
    EIF4A3ENSG00000141543.5482.259601586.38690-1.7179027.9399024.97620K562EIF4A3
    EIF4A3ENSG00000141543.5718.56480910.82600-0.342102.199601.43430K562FMR1
    EIF4A3ENSG00000141543.5567.14580772.03100-0.444902.854801.92560K562FTO
    EIF4A3ENSG00000141543.5965.999801226.68910-0.344703.013201.60770K562FUS
    EIF4A3ENSG00000141543.52222.738401649.787800.430004.736303.97370K562FXR1
    EIF4A3ENSG00000141543.51060.451001417.96020-0.419102.093801.49060K562G3BP2
    EIF4A3ENSG00000141543.5674.30820854.60400-0.341802.271101.55140K562GPKOW
    EIF4A3ENSG00000141543.51908.239002310.64470-0.276102.502201.48020K562HNRNPA1
    EIF4A3ENSG00000141543.5810.811601361.76140-0.7480011.1918010.05930K562HNRNPC
    EIF4A3ENSG00000141543.5949.789901216.23220-0.356702.889001.72240K562HNRNPF
    EIF4A3ENSG00000141543.52048.375501580.453200.374003.887002.60690K562HNRNPL
    EIF4A3ENSG00000141543.51505.133101126.376600.418102.867901.91820K562HNRNPM
    EIF4A3ENSG00000141543.51949.390601298.264100.586308.091806.49110K562KIF1C
    EIF4A3ENSG00000141543.5495.81920729.78460-0.557703.351302.31380K562KRR1
    EIF4A3ENSG00000141543.52071.916501454.381800.510507.063405.48580K562MBNL1
    EIF4A3ENSG00000141543.51680.692401019.415100.721203.676002.62430K562NAA15
    EIF4A3ENSG00000141543.52205.900601554.582900.504705.706404.45600K562PPIG
    EIF4A3ENSG00000141543.5915.132601221.01120-0.416003.423302.40290K562PSIP1
    EIF4A3ENSG00000141543.53396.677803942.77320-0.215102.429001.52690K562PUM2
    EIF4A3ENSG00000141543.53127.461701213.227801.3660035.3839033.39000K562PUS1
    EIF4A3ENSG00000141543.52096.914201182.084500.8268012.5946011.33330K562RBM15
    EIF4A3ENSG00000141543.5717.702801114.25240-0.634608.003206.31910K562RCC2
    EIF4A3ENSG00000141543.51374.256701782.49490-0.375202.547001.76400K562RPS19
    EIF4A3ENSG00000141543.51557.55470980.364200.667802.627201.46990K562SF1
    EIF4A3ENSG00000141543.5653.89270857.30890-0.390802.739801.48070K562SLBP
    EIF4A3ENSG00000141543.51289.253301747.44490-0.438704.067202.03800K562SRP68
    EIF4A3ENSG00000141543.51138.831301419.26910-0.317602.991001.40530K562SRSF9
    EIF4A3ENSG00000141543.5535.525801694.29570-1.6617035.2308031.80670K562SUPV3L1
    EIF4A3ENSG00000141543.51610.086001250.547000.364503.428402.51510K562SYNCRIP
    EIF4A3ENSG00000141543.5812.614901174.37970-0.531304.551203.32570K562TIAL1
    EIF4A3ENSG00000141543.5948.515301247.89210-0.395803.419102.34640K562TRIM56
    EIF4A3ENSG00000141543.51019.068101793.21320-0.8153011.420009.30650K562UCHL5
    EIF4A3ENSG00000141543.51401.079001658.55290-0.243402.705301.99410K562UPF1
    EIF4A3ENSG00000141543.51285.898601826.00800-0.505904.920803.13610K562XRN2
    EIF4A3ENSG00000141543.52825.981403717.51760-0.395604.492203.35100K562ZC3H8
    Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

    *: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
    **: "-log(0)" was displayed as "99999.99999".






    The Knockdown/knockout RNA-Seq assay for EIF4A3 is not available on ENCORE database.





    2 RBPs can affect the splicing of EIF4A3 :

    Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
    SEEIF4A3ENSG00000141543.5chr17-781134687811353378112819781129617811380678113939-0.060000.002780.04718excludedK562SF3B4
    SEEIF4A3ENSG00000141543.5chr17-781151177811518078113806781139397811558078115647-0.077000.000000.00017excludedK562SF3B4
    A3SSEIF4A3ENSG00000141543.5chr17-7811346878113682781134687811354978113806781140130.065000.000000.00000longerK562AQR
    A3SSEIF4A3ENSG00000141543.5chr17-7811380678114007781138067811393978115117781152980.068000.000000.00000longerK562AQR

    *: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
    **: "-log(0)" was displayed as "99999.99999".





    The Knockdown/knockout RNA-Seq assay for EIF4A3 is not avaliable on ENCORE database.