CASP10

General Information

Gene Name       : CASP10
Gene ID             : ENSG00000003400.14
Essential Gene : No

Functions

Localization

Domains (AlphaFold: CASP10)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878CASP10ENSG00000003400.149.357.818.58ENCSR000AEF
HepG2CASP10ENSG00000003400.148.0312.8010.41ENCSR985KAT
K562CASP10ENSG00000003400.147.177.157.16ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for CASP10 is not avaliable on ENCORE database.



Proteins bound to RNA
  • CASP10 RNA is bound by 16 proteins.  







eCLIP assay for CASP10 is not avaliable on ENCORE database.





16 proteins are bound to CASP10 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr2202060651202060708+3'-UTR,CDS,intron-Proximal6.3022311.46503HepG2PRPF8
chr2202082426202082457+3'-UTR,CDS,intron-Distal3.291073.27569HepG2BCLAF1
chr2202068445202068513+3'-UTR,CDS,intron-Distal,intron-Proximal5.540763.70131HepG2PRPF8
chr2202060654202060744+3'-UTR,CDS,intron-Proximal3.515956.43995K562PRPF8
chr2202082832202082908+3'-UTR,intron-Distal4.1679318.73632K562UPF1
chr2202084448202084546+3'-UTR,intron-Distal3.217707.14729K562UPF1
chr2202082966202083011+3'-UTR,intron-Distal5.030926.81621K562UPF1
chr2202083702202083754+3'-UTR,intron-Distal4.158209.37691K562UPF1
chr2202082651202082758+3'-UTR,intron-Distal4.0710510.93151HepG2UPF1
chr2202083287202083350+3'-UTR,intron-Distal4.7640711.97213K562UPF1
chr2202083833202083892+3'-UTR,intron-Distal3.6978113.62037HepG2UPF1
chr2202082296202082374+3'-UTR,CDS,intron-Distal,intron-Proximal3.307684.97118HepG2U2AF2
chr2202068438202068503+3'-UTR,CDS,intron-Distal,intron-Proximal4.227575.09028HepG2U2AF2
chr2202082819202082832+3'-UTR,intron-Distal4.4127112.03763K562UPF1
chr2202083198202083287+3'-UTR,intron-Distal3.8278212.75948K562UPF1
chr2202072784202072915+3'-UTR,CDS,intron-Distal,intron-Proximal3.647443.32039HepG2PPIG
chr2202073879202074000+3'-UTR,CDS3.311786.04751HepG2GRWD1
chr2202083887202083950+3'-UTR,intron-Distal4.448333.78860K562AKAP1
chr2202073782202073842+3'-UTR,CDS,intron-Proximal4.2378010.83393HepG2U2AF2
chr2202084003202084057+3'-UTR,intron-Distal5.295617.35154K562UPF1
chr2202065450202065539+3'-UTR,intron-Distal,polyA_site3.763075.12237K562CSTF2T
chr2202074021202074130+3'-UTR,CDS5.002576.05814HepG2RBM15
chr2202047961202048035+5'-UTR,intron-Proximal3.026884.31951HepG2BCLAF1
chr2202057749202057851+5'-UTR,CDS,intron-Proximal4.3460911.55759HepG2BCLAF1
chr2202047904202047972+5'-UTR4.098873.77023K562ZNF622
chr2202050825202050893+CDS,intron-Proximal4.578509.43475HepG2PRPF8
chr2202050841202050956+CDS,intron-Distal,intron-Proximal4.469394.96013K562PRPF8
chr2202050682202050731+CDS4.419183.81597K562RBM15
chr2202050749202050811+CDS3.858933.06853K562LIN28B
chr2202065456202065524+intron-Distal4.615854.24478HepG2CSTF2
chr2202050937202051000+intron-Distal,intron-Proximal3.572793.24593HepG2XPO5
chr2202076082202076197+intron-Distal4.294808.76637HepG2QKI
chr2202058826202058928+intron-Distal3.786885.90050K562TARDBP
chr2202050847202050910+intron-Proximal4.333024.49024K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for CASP10 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for CASP10 is not available on ENCORE database.

  • 82 RBPs can affect the levels of CASP10.  








The Knockdown/knockout RNA-Seq assay for CASP10 is not available on ENCORE database.





82 RBPs can affect the gene expression of CASP10 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
CASP10ENSG00000003400.10813.04350556.807400.546104.770603.39670HepG2AATF
CASP10ENSG00000003400.10622.00860740.88680-0.252301.961301.43270HepG2ACO1
CASP10ENSG00000003400.101518.815401076.643500.496308.682207.57930HepG2AUH
CASP10ENSG00000003400.10651.45940322.217501.0155012.0333010.90350HepG2BOP1
CASP10ENSG00000003400.10795.03930546.247900.541405.277704.25470HepG2CALR
CASP10ENSG00000003400.10459.67600346.643200.407102.305101.31560HepG2CSTF2
CASP10ENSG00000003400.10793.15030570.104000.476302.614401.31400HepG2CSTF2T
CASP10ENSG00000003400.10821.54750992.70110-0.273002.207701.62360HepG2CELF1
CASP10ENSG00000003400.10861.746101067.33720-0.308703.329902.52980HepG2DAZAP1
CASP10ENSG00000003400.10557.42970685.20680-0.297702.599701.78830HepG2DDX19B
CASP10ENSG00000003400.101150.24890874.856500.394703.168301.78860HepG2DDX47
CASP10ENSG00000003400.10756.99290335.911801.172108.556106.89490HepG2DDX59
CASP10ENSG00000003400.101042.66140574.926900.8587012.2273010.36350HepG2DHX30
CASP10ENSG00000003400.10511.14660708.82380-0.471704.759003.91420HepG2DKC1
CASP10ENSG00000003400.10709.96120590.788300.265002.180201.58830HepG2DNAJC2
CASP10ENSG00000003400.10402.44090544.55050-0.436302.303701.46080HepG2EEF2
CASP10ENSG00000003400.10777.14560565.706600.458002.591201.52500HepG2AGO1
CASP10ENSG00000003400.101339.911101010.098200.407502.961302.34770HepG2EIF2S1
CASP10ENSG00000003400.10694.164801116.28510-0.685405.993905.05600HepG2EIF4A3
CASP10ENSG00000003400.10586.880901086.84520-0.889007.666506.55140HepG2EIF4B
CASP10ENSG00000003400.101400.916401053.045500.411705.692304.56580HepG2EIF4G1
CASP10ENSG00000003400.101312.980501008.740900.380202.665901.86520HepG2EIF4G2
CASP10ENSG00000003400.10567.15520723.96460-0.352202.436601.65400HepG2EWSR1
CASP10ENSG00000003400.10936.56810600.919200.640107.312406.07250HepG2FUBP3
CASP10ENSG00000003400.10846.958701126.26120-0.411202.861002.15700HepG2FXR1
CASP10ENSG00000003400.10572.28740335.299200.771205.791704.88940HepG2GPKOW
CASP10ENSG00000003400.10662.873401039.34040-0.648904.329302.93890HepG2GRSF1
CASP10ENSG00000003400.10462.96070601.81040-0.378402.250301.66370HepG2HNRNPA1
CASP10ENSG00000003400.10479.76550669.38690-0.480503.408402.64540HepG2HNRNPC
CASP10ENSG00000003400.10513.39990664.96250-0.373203.267302.61250HepG2HNRNPU
CASP10ENSG00000003400.10602.25960869.75900-0.530203.379702.01560HepG2HSPD1
CASP10ENSG00000003400.10671.13740508.489300.400302.651201.94140HepG2IGF2BP1
CASP10ENSG00000003400.10530.85930679.23990-0.355603.438002.62720HepG2ILF2
CASP10ENSG00000003400.10547.52750776.20240-0.503502.932702.07690HepG2LARP4
CASP10ENSG00000003400.10496.06910749.83780-0.596004.140302.65760HepG2LIN28B
CASP10ENSG00000003400.10731.487101126.65430-0.623105.751704.81720HepG2MAGOH
CASP10ENSG00000003400.10751.364101132.96390-0.592504.730103.92260HepG2MATR3
CASP10ENSG00000003400.10753.660001159.65460-0.621705.540904.65920HepG2NCBP2
CASP10ENSG00000003400.10412.42780283.741500.539503.033102.24980HepG2NSUN2
CASP10ENSG00000003400.101640.973601026.238900.677104.078702.98650HepG2PABPC1
CASP10ENSG00000003400.10404.01720658.21900-0.704209.191307.79200HepG2PARN
CASP10ENSG00000003400.10922.318301088.17520-0.238601.935901.41380HepG2PCBP1
CASP10ENSG00000003400.10887.05660561.955800.6585010.174308.82600HepG2PRPF4
CASP10ENSG00000003400.10765.783201072.52510-0.486007.656506.77250HepG2PUM1
CASP10ENSG00000003400.10749.004201071.72960-0.516905.731704.77770HepG2PUM2
CASP10ENSG00000003400.10970.63080754.639000.363004.181103.45070HepG2PUS1
CASP10ENSG00000003400.102211.294801199.111200.8828022.2403020.71840HepG2QKI
CASP10ENSG00000003400.10308.85640687.52010-1.154508.054606.89020HepG2RAVER1
CASP10ENSG00000003400.101084.99230662.486900.7116010.255408.75580HepG2RBM15
CASP10ENSG00000003400.10782.259501033.15270-0.401304.160703.55850HepG2RBM22
CASP10ENSG00000003400.10490.08200860.82330-0.812707.629605.97300HepG2RBM27
CASP10ENSG00000003400.10737.776101232.29390-0.7401013.2579012.23380HepG2NELFE
CASP10ENSG00000003400.10827.493301147.82590-0.472106.069605.20570HepG2RECQL
CASP10ENSG00000003400.10240.68360430.13930-0.837707.172106.23620HepG2RPS19
CASP10ENSG00000003400.10580.12340793.96030-0.452702.785901.98310HepG2RPS2
CASP10ENSG00000003400.10723.189701127.67440-0.640904.682003.64300HepG2RPS3A
CASP10ENSG00000003400.10715.41150592.187900.272602.164301.58230HepG2SAFB2
CASP10ENSG00000003400.10499.64710717.55050-0.522202.945802.24900HepG2SF3A3
CASP10ENSG00000003400.10427.86440316.709500.433902.177101.54640HepG2SF3B1
CASP10ENSG00000003400.10397.28090690.60700-0.7977013.4570012.20330HepG2SMN1
CASP10ENSG00000003400.101458.656501166.922000.321804.321403.73540HepG2SRFBP1
CASP10ENSG00000003400.10667.37510507.363400.395403.101302.37020HepG2SRSF7
CASP10ENSG00000003400.101432.76600978.970300.5494010.9836010.01280HepG2SRSF9
CASP10ENSG00000003400.10928.778401134.49540-0.288602.928902.29290HepG2SUCLG1
CASP10ENSG00000003400.10753.10360549.255600.455302.722602.05020HepG2SUPV3L1
CASP10ENSG00000003400.101046.21750646.195200.6950010.008909.16060HepG2TIAL1
CASP10ENSG00000003400.10685.86660987.07750-0.525205.268704.02190HepG2TUFM
CASP10ENSG00000003400.10862.87820636.358800.439205.158304.25160HepG2UPF1
CASP10ENSG00000003400.10481.35170614.37760-0.352002.683502.09380HepG2UTP3
CASP10ENSG00000003400.10553.82980755.98190-0.448902.287601.32630HepG2XRCC6
CASP10ENSG00000003400.10396.59970284.242700.480502.589201.45300K562AARS
CASP10ENSG00000003400.10662.03410811.50320-0.293701.809301.31470K562AQR
CASP10ENSG00000003400.10731.22670978.77960-0.420703.322502.25400K562CELF1
CASP10ENSG00000003400.10342.26330502.59160-0.554305.033104.19010K562DDX47
CASP10ENSG00000003400.10567.60760439.972000.367402.651501.94470K562EIF2S2
CASP10ENSG00000003400.10133.14580221.07890-0.731602.346301.42680K562EIF3A
CASP10ENSG00000003400.10279.14100403.04600-0.530003.787202.86610K562EIF3G
CASP10ENSG00000003400.10593.47100795.79430-0.423204.147503.00360K562EIF4G2
CASP10ENSG00000003400.10498.83900356.315300.485303.416501.90830K562FUS
CASP10ENSG00000003400.10314.50940413.26700-0.394002.391001.33890K562GLRX3
CASP10ENSG00000003400.10563.93740703.73070-0.319502.139101.39600K562MAGOH
CASP10ENSG00000003400.10554.33280702.29460-0.341302.393301.54130K562MATR3
CASP10ENSG00000003400.10321.13390434.49760-0.436203.067002.21830K562MTPAP
CASP10ENSG00000003400.10615.99600426.077700.531704.474402.89750K562NCBP2
CASP10ENSG00000003400.10322.26730482.75860-0.583005.768204.74480K562NSUN2
CASP10ENSG00000003400.10881.28650683.722600.366102.988202.30060K562PTBP1
CASP10ENSG00000003400.10592.24100771.10610-0.380703.068202.44930K562RBM15
CASP10ENSG00000003400.10350.87090455.47400-0.376402.686201.85140K562WDR43
CASP10ENSG00000003400.10703.09080384.184200.871803.760001.71590K562XPO5
CASP10ENSG00000003400.10709.77420914.21880-0.365202.752901.89230K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for CASP10 is not available on ENCORE database.





12 RBPs can affect the splicing of CASP10 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SECASP10ENSG00000003400.10chr2+2020684522020684892020605642020606712020727972020729060.526000.000010.00037includedK562SRSF1
SECASP10ENSG00000003400.10chr2+2020684522020684892020605642020606712020727972020729060.428000.000170.01554includedHepG2RBM22
SECASP10ENSG00000003400.10chr2+2020684522020684892020605642020606712020727972020729060.443000.000070.04312includedHepG2DHX30
SECASP10ENSG00000003400.10chr2+2020730122020731902020727972020729062020737922020742850.119000.001480.01701includedK562AQR
SECASP10ENSG00000003400.10chr2+202052428202052522202050493202050847202057706202057842-0.107000.003080.03129excludedK562AQR
SECASP10ENSG00000003400.10chr2+202072797202072906202060564202060671202073792202074285-0.153000.009080.07516excludedK562AQR
SECASP10ENSG00000003400.10chr2+2020684522020684892020605642020606712020727972020729060.359000.000430.06797includedHepG2TIA1
SECASP10ENSG00000003400.10chr2+2020684522020684892020605642020606712020727972020729060.541000.000000.00047includedHepG2SSB
SECASP10ENSG00000003400.10chr2+2020730122020731902020727972020729062020737922020742850.357000.000290.01663includedHepG2HNRNPU
MXECASP10ENSG00000003400.10chr2+2020504932020508472020577062020578422020478912020480312020605642020606710.323000.000150.054971includedHepG2CSTF2T
MXECASP10ENSG00000003400.10chr2+2020605642020606712020727972020729062020577062020578422020737922020742850.211000.005720.076841includedK562PUS1
MXECASP10ENSG00000003400.10chr2+2020524282020525222020605642020606712020504932020508472020727972020729060.308000.000860.017401includedK562SRSF1
MXECASP10ENSG00000003400.10chr2+2020684522020684892020727972020729062020605642020606712020737922020742850.332000.000140.003731includedK562SRSF1
MXECASP10ENSG00000003400.10chr2+2020706042020706962020727972020729062020684522020684892020737922020742850.270000.003920.071271includedHepG2DDX55
MXECASP10ENSG00000003400.10chr2+202052428202052522202057706202057842202050493202050847202060564202060671-0.217000.000420.026682includedHepG2DDX3X
MXECASP10ENSG00000003400.10chr2+2020577062020578422020605642020606712020524282020525222020727972020729060.280000.000000.000171includedHepG2SSB
MXECASP10ENSG00000003400.10chr2+202068452202068489202072797202072906202060564202060671202073792202074285-0.409000.005570.067092includedK562HNRNPUL1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for CASP10 is not avaliable on ENCORE database.