AUH

General Information

Gene Name : AUH
Gene ID : ENSG00000148090.11
Essential Gene : No

Functions

RNA stability & decay
Translation regulation
mitochondrial RNA regulation

Localization(RBPImage: AUH)

Nuclei
Nucleoplasm
Cytoplasm
Compartment/Organelle
Mitochondria

Domains (AlphaFold: AUH)

No checked domain (RRM, ZNF, KH, Helicase, Nuclease, dRBM or PUM_HD)

Antibody Validation

MBLI: RN037P

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	AUH	ENSG00000148090.11	1.52	2.30	1.91	ENCSR000AEF
HepG2	AUH	ENSG00000148090.11	12.04	21.00	16.52	ENCSR985KAT
K562	AUH	ENSG00000148090.11	4.43	4.23	4.33	ENCSR000AEO

Assays

2 Released experiments are available on ENCORE database.

Assay Type	Exp_Name	ENCODE ID	Target label	Biosample	Status	Linked Antibody	Controls	Method	Note
knockdown followed by RNA-seq	AUH-BGKLV38-K562	ENCSR395FYF	AUH	K562	Released		ENCSR718EWL	shRNA	KD% = 84.4,63.4
knockdown followed by RNA-seq	AUH-BGHLV37-HepG2	ENCSR409CSO	AUH	HepG2	Released		ENCSR997HCQ	shRNA	KD% = 57.4,45.9

eCLIP

RBP	Exp_UID	Cell_Line	ENCODE_ACCESSION	Control_ENCODE_ACCESSION	ENCODE_Antibody_ID	Antibody	Lot_num	Status	Project
AUH	246	K562	ENCSR541QHS	ENCSR943ZKM	ENCAB000BFE	RN037P	1	Revoked	ENCODE3
AUH	280	HepG2	ENCSR334QFR	ENCSR821VMD	ENCAB000BFE	RN037P	1	Revoked	ENCODE3

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
AUH	ENCAB000BFE	RN037P	1		Released, ENCODE3	Released, ENCODE3	BGHLV37-13, Released, ENCODE3	BGKLV38-27, Released, ENCODE3

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project
AUH	K562	shRNA			BGKLV29-9,BGKLV29-10	BGKLV29-1,BGKLV29-2		NotSatisfied	ENCODE3
AUH	K562	shRNA			BGKLV34-5,BGKLV34-6	BGKLV34-1,BGKLV34-2		NotSatisfied	ENCODE3
AUH	K562	shRNA			BGKLV36-3,BGKLV36-4	BGKLV36-1,BGKLV36-2	0.0,0.0	NotSatisfied	ENCODE3
AUH	K562	shRNA			BGKLV36-5,BGKLV36-6	BGKLV36-1,BGKLV36-2	0.0,0.0	NotSatisfied	ENCODE3
AUH	K562	shRNA			BGKLV38-23,BGKLV38-24	BGKLV38-1,BGKLV38-2	51.3,30.4	NotSatisfied	ENCODE3
AUH	K562	shRNA			BGKLV38-25,BGKLV38-26	BGKLV38-1,BGKLV38-2	69.6,47.6	NotSatisfied	ENCODE3
AUH	K562	shRNA	ENCSR395FYF	ENCSR718EWL	AUH_BGKLV38-27,AUH_BGKLV38-28	NT_BGKLV38-1,NT_BGKLV38-2	84.4,63.4	Released	ENCODE3
AUH	HepG2	shRNA			BGHLV26-3,BGHLV26-4	BGHLV26-1,BGHLV26-2	redo transfection,redo transfection	NotSatisfied	ENCODE3
AUH	HepG2	shRNA			BGHLV30-15,BGHLV30-16	BGHLV30-1,BGHLV30-2		NotSatisfied	ENCODE3
AUH	HepG2	shRNA			BGHLV35-3,BGHLV35-4	BGHLV35-1,BGHLV35-2	0.0,0.0	NotSatisfied	ENCODE3
AUH	HepG2	shRNA			BGHLV35-5,BGHLV35-6	BGHLV35-1,BGHLV35-2	no clear band,	NotSatisfied	ENCODE3
AUH	HepG2	shRNA	ENCSR409CSO	ENCSR997HCQ	AUH_BGHLV37-13,AUH_BGHLV37-14	NT_BGHLV37-1,NT_BGHLV37-2	57.4,45.9	Released	ENCODE3
AUH	HepG2	shRNA			BGHLV37-15,BGHLV37-16	BGHLV37-1,BGHLV37-2	0.0,0.0	NotSatisfied	ENCODE3

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

AUH: Click to RBP Image Database

Nuclei

Nucleoplasm

Cytoplasm

Compartment/Organelle

Mitochondria

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
AUH	Product_ID: RN037P Lot_ID: 1 Source: MBLI Target Name: AUH-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for AUH is not avaliable on ENCORE database.

Proteins bound to RNA

AUH RNA is bound by 30 proteins.

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eCLIP assay for AUH is not avaliable on ENCORE database.

30 proteins are bound to AUH RNA:

Show entries

Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr9	94118220	94118287	-	CDS,intron-Distal,intron-Proximal	5.44923	27.89128	HepG2	U2AF2
chr9	94049663	94049760	-	intron-Distal	4.70048	22.61358	HepG2	QKI
chr9	94087648	94087686	-	CDS,intron-Distal	5.06588	20.96897	HepG2	BCLAF1
chr9	94118163	94118178	-	CDS,intron-Distal,intron-Proximal	4.68262	19.87774	HepG2	BCLAF1
chr9	94060265	94060322	-	CDS,intron-Distal,intron-Proximal	3.89058	19.82091	HepG2	BCLAF1
chr9	94119896	94119986	-	intron-Distal	4.45410	18.71835	K562	QKI
chr9	94118383	94118434	-	CDS,intron-Distal,intron-Proximal	4.47476	15.99938	HepG2	BCLAF1
chr9	94008185	94008286	-	intron-Distal	4.85374	15.24958	HepG2	SUGP2
chr9	94118178	94118206	-	CDS,intron-Distal	3.82948	14.98716	HepG2	BCLAF1
chr9	94049762	94049820	-	intron-Distal	4.87530	14.28056	HepG2	QKI
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 126 entries

eCLIP assay for AUH is not avaliable on ENCORE database.

Diffrential Expression

6,602 differentially expressed genes after Knockdown/Knockout AUH protein.

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77 RBPs can affect the levels of AUH.

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6,602 differentially expressed genes after Knockdown/Knockout AUH protein :

Only display 100 entries as example. Please click "View All" button to see all 6,602 entries.

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
TNFRSF12A	ENSG00000006327.9	1933.31970	640.59910	1.59350	73.23170	70.64750	HepG2	AUH
NCAPD2	ENSG00000010292.8	2807.57230	6165.90600	-1.13500	63.68610	61.23350	HepG2	AUH
ITGA3	ENSG00000005884.13	1429.57580	178.83480	2.99880	39.48820	37.42350	HepG2	AUH
GDE1	ENSG00000006007.7	4503.72780	2476.41360	0.86280	35.99240	34.01850	HepG2	AUH
LASP1	ENSG00000002834.13	14510.84890	8592.86130	0.75580	35.28530	33.32910	HepG2	AUH
MAP3K9	ENSG00000006432.11	1428.17170	675.37100	1.08030	31.61880	29.74540	HepG2	AUH
ASB4	ENSG00000005981.8	610.28020	218.33340	1.48280	29.14620	27.34230	HepG2	AUH
RHBDF1	ENSG00000007384.11	771.59310	310.36810	1.31380	28.82380	27.03410	HepG2	AUH
TFPI	ENSG00000003436.10	20109.67420	12770.79870	0.65490	27.87400	26.10000	HepG2	AUH
IDS	ENSG00000010404.13	1847.84160	913.88910	1.01570	26.84550	25.10160	HepG2	AUH
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 100 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

77 RBPs can affect the gene expression of AUH :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
AUH	ENSG00000148090.7	220.70610	571.94900	-1.37380	24.49660	22.82540	HepG2	AUH
AUH	ENSG00000148090.7	154.49520	432.47490	-1.48510	19.24530	17.14160	HepG2	HNRNPM
AUH	ENSG00000148090.7	1026.65690	619.91720	0.72770	13.64000	12.75330	HepG2	SRFBP1
AUH	ENSG00000148090.7	275.78950	732.26610	-1.40880	13.42940	11.79510	HepG2	CNOT7
AUH	ENSG00000148090.7	338.01590	592.65970	-0.81010	10.36840	9.32560	HepG2	UTP3
AUH	ENSG00000148090.7	739.54210	396.26920	0.90010	9.39410	7.99250	HepG2	FUBP3
AUH	ENSG00000148090.7	292.75170	529.13300	-0.85400	8.43280	7.46840	HepG2	PUF60
AUH	ENSG00000148090.7	540.51730	297.49770	0.86140	8.82480	7.17610	HepG2	DHX30
AUH	ENSG00000148090.7	347.38940	565.83100	-0.70380	7.69170	6.99520	HepG2	SRSF1
AUH	ENSG00000148090.7	327.70710	554.30570	-0.75830	8.26740	6.97160	HepG2	NOL12
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 86 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for AUH is not available on ENCORE database.

21 RBPs can affect the splicing of AUH :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	AUH	ENSG00000148090.7	chr9	-	94122652	94122722	94118369	94118437	94123909	94124169	-0.13300	0.00000	0.00004	excluded	HepG2	U2AF1
SE	AUH	ENSG00000148090.7	chr9	-	94122652	94122722	94118369	94118437	94123909	94124169	-0.11000	0.00000	0.00005	excluded	HepG2	TBRG4
SE	AUH	ENSG00000148090.7	chr9	-	94122652	94122722	94118369	94118437	94123909	94124169	-0.20200	0.00000	0.00028	excluded	HepG2	AKAP1
SE	AUH	ENSG00000148090.7	chr9	-	94122560	94122722	94118369	94118437	94123909	94124169	0.06500	0.00000	0.00001	included	HepG2	SFPQ
SE	AUH	ENSG00000148090.7	chr9	-	93978340	93978388	93976096	93976707	93979558	93979609	-0.18200	0.00000	0.00001	excluded	HepG2	SF3A3
SE	AUH	ENSG00000148090.7	chr9	-	94122652	94122722	94118369	94118437	94123909	94124169	0.20000	0.00000	0.00003	included	K562	HNRNPUL1
SE	AUH	ENSG00000148090.7	chr9	-	94122652	94122722	94118369	94118437	94123909	94124169	-0.18500	0.00002	0.00370	excluded	HepG2	DDX3X
SE	AUH	ENSG00000148090.7	chr9	-	94122652	94122722	94118369	94118437	94123909	94124169	0.29000	0.00005	0.00990	included	HepG2	HNRNPM
SE	AUH	ENSG00000148090.7	chr9	-	94122652	94122722	94118369	94118437	94123909	94124169	0.27000	0.00005	0.05313	included	K562	DDX21
SE	AUH	ENSG00000148090.7	chr9	-	94122652	94122722	94118369	94118437	94123909	94124169	0.23500	0.00006	0.01391	included	K562	HNRNPM

Showing 1 to 10 of 27 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

AUH

General Information

Functions

Localization(RBPImage: AUH)

Domains (AlphaFold: AUH)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for AUH is not avaliable on ENCORE database.

30 proteins are bound to AUH RNA:

eCLIP assay for AUH is not avaliable on ENCORE database.

Diffrential Expression

6,602 differentially expressed genes after Knockdown/Knockout AUH protein :

77 RBPs can affect the gene expression of AUH :

The Knockdown/knockout RNA-Seq assay for AUH is not available on ENCORE database.

21 RBPs can affect the splicing of AUH :

The Knockdown/knockout RNA-Seq assay for AUH is not avaliable on ENCORE database.