PAFAH1B1

General Information

Gene Name       : PAFAH1B1
Gene ID             : ENSG00000007168.12
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: PAFAH1B1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PAFAH1B1ENSG00000007168.1255.0841.6648.37ENCSR000AEF
HepG2PAFAH1B1ENSG00000007168.1236.5550.5743.56ENCSR985KAT
K562PAFAH1B1ENSG00000007168.1235.2827.0431.16ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PAFAH1B1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PAFAH1B1 RNA is bound by 34 proteins.  







eCLIP assay for PAFAH1B1 is not avaliable on ENCORE database.





34 proteins are bound to PAFAH1B1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1725857832585917+3'-UTR,intron-Distal3.587025.49597K562IGF2BP1
chr1725413922541414+3'-UTR,5'-UTR,intron-Distal,intron-Proximal4.013063.59941K562UCHL5
chr1725880472588097+3'-UTR3.982616.14808K562UPF1
chr1725693082569359+3'-UTR,CDS,intron-Distal,intron-Proximal3.545145.76104HepG2BCLAF1
chr1725703212570455+3'-UTR,CDS,intron-Distal4.2332420.29031HepG2BCLAF1
chr1725862072586281+3'-UTR,intron-Distal3.463523.78824HepG2KHSRP
chr1725415172541614+3'-UTR,5'-UTR,CDS,intron-Distal3.062934.91547HepG2GRWD1
chr1725413892541421+3'-UTR,5'-UTR,intron-Distal,intron-Proximal3.756573.14999HepG2GRWD1
chr1725413912541410+3'-UTR,5'-UTR,intron-Distal,intron-Proximal3.291073.27569HepG2BCLAF1
chr1725852032585305+3'-UTR,intron-Distal3.401274.44589K562PUM2
chr1725414442541512+3'-UTR,5'-UTR,intron-Distal3.474734.93175HepG2GRWD1
chr1725702852570393+3'-UTR,CDS,intron-Distal,intron-Proximal3.4630821.11190K562ZNF622
chr1725887662588829+3'-UTR4.8980610.00297K562PUM2
chr1725413922541413+3'-UTR,5'-UTR,intron-Distal,intron-Proximal3.357463.59112HepG2PPIG
chr1725702852570321+3'-UTR,CDS,intron-Distal,intron-Proximal3.697498.19964HepG2BCLAF1
chr1725702852570374+3'-UTR,CDS,intron-Distal,intron-Proximal4.310443.22063K562TRA2A
chr1725881632588210+3'-UTR4.600465.25389K562UPF1
chr1724970032497073+5'-UTR,intron-Distal3.513735.10069HepG2GRWD1
chr1724970082497085+5'-UTR,intron-Distal3.000036.68409K562UCHL5
chr1724972072497264+5'-UTR,intron-Distal3.274527.77500HepG2PCBP2
chr1724970232497080+5'-UTR,intron-Distal3.662329.30518HepG2PPIG
chr1724970012497095+5'-UTR,intron-Distal3.913455.66767K562FTO
chr1724969432497095+5'-UTR,intron-Distal6.0359113.76350K562ZNF622
chr1724971842497276+5'-UTR,intron-Distal3.282004.24915K562PCBP1
chr1724970262497079+5'-UTR,intron-Distal4.078329.09300HepG2DDX3X
chr1724972222497300+5'-UTR,intron-Distal3.285566.72797HepG2DDX3X
chr1725736052573662+CDS,intron-Distal,intron-Proximal4.996517.36776HepG2PRPF8
chr1725850172585074+CDS,intron-Distal,intron-Proximal4.303579.47387HepG2U2AF2
chr1725836052583656+CDS,intron-Distal,intron-Proximal4.994285.68502HepG2PRPF8
chr1725774472577507+CDS,intron-Distal,intron-Proximal3.391103.95937K562UCHL5
chr1725797982579901+CDS,intron-Distal,intron-Proximal3.161096.32494K562UCHL5
chr1725773572577413+CDS,intron-Distal,intron-Proximal3.514444.56058HepG2BCLAF1
chr1725850202585032+CDS,intron-Distal,intron-Proximal4.321474.55095K562YBX3
chr1725775692577729+CDS,intron-Distal,intron-Proximal3.589125.19487K562PRPF8
chr1725775292577584+CDS,intron-Distal,intron-Proximal4.430567.16838HepG2BCLAF1
chr1725798482579899+CDS,intron-Distal3.097815.75243K562ZNF622
chr1725835122583595+CDS,intron-Distal3.912383.15006K562RBM15
chr1725773422577398+CDS,intron-Distal,intron-Proximal3.104393.76335K562SF3B4
chr1725850322585066+CDS,intron-Distal3.369373.69775K562YBX3
chr1725798482579903+CDS,intron-Distal,intron-Proximal3.173684.77136HepG2PPIG
chr1725835982583644+CDS,intron-Distal,intron-Proximal4.224633.15006K562RBM15
chr1725835962583615+CDS,intron-Distal,intron-Proximal3.150633.07714K562YBX3
chr1725798092579905+CDS,intron-Distal,intron-Proximal3.370918.84415HepG2BCLAF1
chr1725835762583619+CDS,intron-Distal,intron-Proximal3.138083.94979HepG2BCLAF1
chr1725070412507093+intron-Distal3.715823.24242HepG2HNRNPC
chr1725584912558564+intron-Distal4.175194.13603K562TARDBP
chr1724969382496994+intron-Distal4.481343.61005K562PUM1
chr1725776112577655+intron-Distal,intron-Proximal4.990784.44893K562RBM22
chr1725772642577334+intron-Distal,intron-Proximal6.3119115.63115K562SF3B4
chr1725058462505931+intron-Distal5.334875.61339K562QKI
chr1725328422532873+intron-Distal4.341033.30687K562EXOSC5
chr1725021132502179+intron-Distal5.073296.44072HepG2HNRNPM
chr1725840922584155+intron-Distal3.063833.19398HepG2XPO5
chr1725771432577206+intron-Distal3.321205.75743K562KHSRP
chr1725772062577222+intron-Distal3.758285.78064K562KHSRP
chr1725155162515561+intron-Distal3.822893.24242HepG2HNRNPC
chr1724969572497026+intron-Distal3.5157811.70999HepG2DDX3X
chr1725058382505915+intron-Distal5.1405624.91053HepG2QKI
chr1725339432534001+intron-Distal4.801166.10662K562HNRNPM
chr1725757392575876+intron-Distal,intron-Proximal4.099175.04794HepG2KHSRP
chr1725023112502414+intron-Distal3.187314.19275K562EXOSC5
chr1725151942515432+intron-Distal3.578896.07399HepG2SFPQ
chr1724969522496997+intron-Distal4.229983.32421K562NCBP2
chr1725318992531960+intron-Distal3.781924.02190K562EXOSC5
chr1725799132579995+intron-Distal,intron-Proximal4.031858.11145K562KHSRP
chr1725332612533333+intron-Distal5.175957.71416K562EXOSC5
chr1725315332531587+intron-Distal3.999975.80937K562EXOSC5
chr1725800102580121+intron-Distal4.155488.55611K562KHSRP
chr1725318302531878+intron-Distal4.575775.12361K562EXOSC5
chr1725083542508436+intron-Distal3.350893.42785HepG2HNRNPM
chr1725058022505917+intron-Distal3.136944.54315HepG2HNRNPL
chr1725730552573152+intron-Distal4.7665911.22811HepG2PTBP1
chr1725826972582753+intron-Distal4.041554.44706K562EIF4G2
chr1725010772501161+intron-Distal4.718926.71516K562TARDBP
chr1725756592575692+intron-Distal3.340033.17919K562KHSRP
chr1725771702577250+intron-Distal3.958593.07287K562TIA1
chr1725059152505977+intron-Distal4.5487021.57073HepG2QKI
chr1725060412506170+intron-Distal3.896279.98581HepG2QKI
chr1725529312553114+intron-Distal3.215163.82074K562KHDRBS1
chr1725057882505953+intron-Distal3.150524.05663K562HNRNPL
chr1725059902506021+intron-Distal3.471623.84494HepG2QKI
chr1725832352583289+intron-Distal3.690574.77518HepG2U2AF2
chr1725308612530932+intron-Distal4.325733.59909K562EXOSC5
chr1725327892532831+intron-Distal4.346054.48560K562EXOSC5
chr1724969552497008+intron-Distal3.521033.73423K562UCHL5
chr1725341142534177+intron-Distal4.889794.80466K562EXOSC5
chr1725829292583005+intron-Distal4.779765.14653K562EIF4G2
chr1725716332571757+intron-Distal4.502324.05848HepG2QKI
chr1725730612573158+intron-Distal5.019575.89856K562PTBP1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PAFAH1B1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PAFAH1B1 is not available on ENCORE database.

  • 72 RBPs can affect the levels of PAFAH1B1.  








The Knockdown/knockout RNA-Seq assay for PAFAH1B1 is not available on ENCORE database.





72 RBPs can affect the gene expression of PAFAH1B1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PAFAH1B1ENSG00000007168.81334.060301841.44390-0.465004.165003.02640HepG2ABCF1
PAFAH1B1ENSG00000007168.83279.808602122.465800.6278020.7151019.39570HepG2ACO1
PAFAH1B1ENSG00000007168.83718.899702694.370300.4648010.558209.36110HepG2AUH
PAFAH1B1ENSG00000007168.81548.765202121.99310-0.4543010.439809.31750HepG2CKAP4
PAFAH1B1ENSG00000007168.8868.591701568.75460-0.8529012.3919011.05390HepG2CPSF6
PAFAH1B1ENSG00000007168.83391.820602683.505000.337805.184604.35460HepG2CELF1
PAFAH1B1ENSG00000007168.82018.818802885.65020-0.5154015.5624014.05310HepG2DAZAP1
PAFAH1B1ENSG00000007168.81476.732201937.72880-0.392003.850103.06300HepG2DDX21
PAFAH1B1ENSG00000007168.81042.543501532.99300-0.556204.825903.02510HepG2DDX28
PAFAH1B1ENSG00000007168.82125.460102624.43020-0.304202.076601.52610HepG2DDX3X
PAFAH1B1ENSG00000007168.82974.893702254.465200.400002.900202.26930HepG2DDX6
PAFAH1B1ENSG00000007168.81402.358001652.47720-0.236802.249801.60980HepG2DNAJC21
PAFAH1B1ENSG00000007168.81146.541501637.85800-0.5145011.5236010.29310HepG2DNAJC2
PAFAH1B1ENSG00000007168.82800.032102167.246900.369502.870902.26720HepG2EIF2S1
PAFAH1B1ENSG00000007168.81467.708601168.703900.328602.451801.59560HepG2EIF3D
PAFAH1B1ENSG00000007168.83132.219702331.941000.425602.653201.97870HepG2EIF4B
PAFAH1B1ENSG00000007168.84096.483003093.428800.405109.009508.02840HepG2ETF1
PAFAH1B1ENSG00000007168.81138.393601778.37210-0.643606.454705.50440HepG2GPKOW
PAFAH1B1ENSG00000007168.81646.638402026.34030-0.299404.054002.88530HepG2HDGF
PAFAH1B1ENSG00000007168.81344.769701855.67520-0.464604.948004.04140HepG2HNRNPC
PAFAH1B1ENSG00000007168.81486.984601727.71160-0.216502.111501.47810HepG2HNRNPF
PAFAH1B1ENSG00000007168.81800.139202269.94740-0.334602.745402.05110HepG2HNRNPK
PAFAH1B1ENSG00000007168.81592.957901882.98110-0.241303.307302.51190HepG2ILF2
PAFAH1B1ENSG00000007168.81246.721301940.19270-0.6381018.5532016.20880HepG2KIF1C
PAFAH1B1ENSG00000007168.81849.228802417.38620-0.386503.032502.34590HepG2MAGOH
PAFAH1B1ENSG00000007168.81971.931701504.752700.390003.987203.02040HepG2MSI2
PAFAH1B1ENSG00000007168.81713.528102488.16670-0.538105.135104.28440HepG2NCBP2
PAFAH1B1ENSG00000007168.81139.876501644.17360-0.528508.635407.38220HepG2PPIL4
PAFAH1B1ENSG00000007168.82760.197102154.328500.357406.138805.38660HepG2PTBP1
PAFAH1B1ENSG00000007168.82165.754702731.38780-0.334803.450702.79500HepG2PUF60
PAFAH1B1ENSG00000007168.82133.786002899.41600-0.4423012.6403011.56850HepG2PUM1
PAFAH1B1ENSG00000007168.83860.122602897.343300.413805.988205.01470HepG2PUM2
PAFAH1B1ENSG00000007168.83587.279502585.548400.472309.399308.57240HepG2RBM22
PAFAH1B1ENSG00000007168.83274.959502117.488800.6290011.094809.80350HepG2RBM25
PAFAH1B1ENSG00000007168.81479.381301912.05030-0.370102.505201.49690HepG2RCC2
PAFAH1B1ENSG00000007168.83074.408202397.537300.358706.261405.50260HepG2NELFE
PAFAH1B1ENSG00000007168.81078.661701641.64100-0.6059014.1528012.86480HepG2SAFB2
PAFAH1B1ENSG00000007168.82564.920002242.883300.193502.125001.59660HepG2SF3B4
PAFAH1B1ENSG00000007168.82235.319002618.82570-0.228403.627302.84200HepG2SLBP
PAFAH1B1ENSG00000007168.81495.543301914.43980-0.356306.807505.86830HepG2SMN1
PAFAH1B1ENSG00000007168.84262.274402920.307100.5454017.9989017.01680HepG2SRFBP1
PAFAH1B1ENSG00000007168.83442.462902341.105300.5562015.8943014.95920HepG2SRSF1
PAFAH1B1ENSG00000007168.82674.746801904.631700.4898011.7286010.73270HepG2SRSF9
PAFAH1B1ENSG00000007168.81965.929603067.03410-0.6416022.7615021.25690HepG2SUCLG1
PAFAH1B1ENSG00000007168.82298.379201933.535500.249302.247101.49210HepG2TIA1
PAFAH1B1ENSG00000007168.81427.620201791.24850-0.327403.556503.00430HepG2TIAL1
PAFAH1B1ENSG00000007168.81295.586401807.22460-0.480209.208308.27210HepG2TRIM56
PAFAH1B1ENSG00000007168.82398.848201590.521200.592706.902005.92130HepG2U2AF1
PAFAH1B1ENSG00000007168.8723.848401189.96380-0.717207.552906.29620HepG2UCHL5
PAFAH1B1ENSG00000007168.81572.115601821.54000-0.212502.365901.80270HepG2UTP3
PAFAH1B1ENSG00000007168.81194.847401982.84090-0.730708.506407.25050HepG2XRN2
PAFAH1B1ENSG00000007168.81470.312201255.750000.227502.552001.90210HepG2ZC3H8
PAFAH1B1ENSG00000007168.81614.900502075.01410-0.361707.252006.47540HepG2ZNF622
PAFAH1B1ENSG00000007168.81900.744402540.35670-0.418504.145402.62300K562ABCF1
PAFAH1B1ENSG00000007168.84139.129503061.716500.434904.878804.13900K562AQR
PAFAH1B1ENSG00000007168.81005.271601347.51440-0.422704.328603.34900K562CPSF6
PAFAH1B1ENSG00000007168.81002.303201322.34510-0.399804.263902.91450K562CSTF2
PAFAH1B1ENSG00000007168.84948.054104053.544500.287603.813202.65950K562CELF1
PAFAH1B1ENSG00000007168.81292.514101565.17140-0.276102.316601.36570K562DDX3X
PAFAH1B1ENSG00000007168.83447.997702268.111100.6042016.8664015.37870K562DDX47
PAFAH1B1ENSG00000007168.82032.784702338.19900-0.201901.926001.30770K562EIF2S2
PAFAH1B1ENSG00000007168.82337.458101741.753300.424303.264202.13430K562EIF3D
PAFAH1B1ENSG00000007168.82098.387301666.947800.332002.971602.14700K562EIF3G
PAFAH1B1ENSG00000007168.81288.028501635.19190-0.344302.951802.10470K562EIF4A3
PAFAH1B1ENSG00000007168.84058.453603297.087700.299605.035603.78620K562EIF4G2
PAFAH1B1ENSG00000007168.81072.490401386.51060-0.370503.578802.11160K562EXOSC5
PAFAH1B1ENSG00000007168.81860.456901473.711700.336103.686102.10310K562FUS
PAFAH1B1ENSG00000007168.82156.946301700.526300.342904.638603.88230K562FXR1
PAFAH1B1ENSG00000007168.82195.480201622.861500.435902.861902.14040K562G3BP2
PAFAH1B1ENSG00000007168.81024.506201286.56350-0.328602.546301.78260K562GPKOW
PAFAH1B1ENSG00000007168.82171.111303116.00420-0.521307.516006.25600K562GRSF1
PAFAH1B1ENSG00000007168.81957.211901582.882400.306102.336301.64470K562PRPF8
PAFAH1B1ENSG00000007168.8792.119001033.80910-0.384202.566801.70160K562PSIP1
PAFAH1B1ENSG00000007168.84789.504003597.433300.412805.228404.10950K562PUF60
PAFAH1B1ENSG00000007168.8727.02320943.08530-0.375403.035201.99280K562RCC2
PAFAH1B1ENSG00000007168.8695.03060894.03320-0.363302.466701.51100K562SRFBP1
PAFAH1B1ENSG00000007168.82258.771401895.626200.252803.705102.64040K562SRPK2
PAFAH1B1ENSG00000007168.82602.541602039.377800.351703.928103.09180K562SRSF1
PAFAH1B1ENSG00000007168.82568.408203138.82770-0.289402.862801.32880K562SUCLG1
PAFAH1B1ENSG00000007168.82070.901801625.027300.349703.947102.98940K562U2AF2
PAFAH1B1ENSG00000007168.81517.651501988.22660-0.389606.629305.57130K562UPF1
PAFAH1B1ENSG00000007168.82355.685601769.112300.413008.600107.18990K562WDR43
PAFAH1B1ENSG00000007168.84395.109503627.573600.276802.659801.39900K562WRN
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PAFAH1B1 is not available on ENCORE database.





7 RBPs can affect the splicing of PAFAH1B1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPAFAH1B1ENSG00000007168.8chr17+256866525687502541392254161425693092569384-0.077000.005610.08073excludedK562SF3B4
SEPAFAH1B1ENSG00000007168.8chr17+256866525687502541392254161425693092569384-0.184000.000020.00409excludedK562XRCC6
SEPAFAH1B1ENSG00000007168.8chr17+256866525687502541433254161425693092569384-0.061000.003310.03316excludedK562AQR
SEPAFAH1B1ENSG00000007168.8chr17+256866525687502541392254161425693092569384-0.074000.002690.07963excludedK562TARDBP
A3SSPAFAH1B1ENSG00000007168.8chr17+2568641256875025686652568750254139225416140.142000.000000.00000longerK562AQR
A5SSPAFAH1B1ENSG00000007168.8chr17+2583457258370025834572583614258502225856420.068000.000000.00000longerK562PUS1
A5SSPAFAH1B1ENSG00000007168.8chr17+2583457258370025834572583614258502225856420.065000.000000.00002longerK562AQR
A5SSPAFAH1B1ENSG00000007168.8chr17+2583457258370025834572583614258502225856420.057000.000860.07237longerK562PRPF8
A5SSPAFAH1B1ENSG00000007168.8chr17+258345725837002583457258361425850222588909-0.057000.000270.03039shorterK562FXR1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PAFAH1B1 is not avaliable on ENCORE database.