WRN

General Information

Gene Name       : WRN
Gene ID             : ENSG00000165392.9
Essential Gene : No

Functions

Localization(RBPImage: WRN)

Domains (AlphaFold: WRN)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878WRNENSG00000165392.919.9416.7118.33ENCSR000AEF
HepG2WRNENSG00000165392.95.3910.357.87ENCSR985KAT
K562WRNENSG00000165392.928.1227.8728.00ENCSR000AEO

Assays

3 Released experiments are available on ENCORE database.

Assay TypeExp_NameENCODE IDTarget labelBiosampleStatusLinked AntibodyControlsMethodNote
eCLIPeCLIP: 416ENCSR038JMEWRNK562ReleasedENCAB362RRMENCSR925ZRV  
knockdown followed by RNA-seq WRN-BGKLV38-K562ENCSR165BCFWRNK562ReleasedENCSR718EWL   shRNAKD% = 71.2,80.4
knockdown followed by RNA-seq WRN-BGHLV37-HepG2ENCSR093FHCWRNHepG2ReleasedENCSR225PRV   shRNAKD% = 98.1,89.6






  eCLIP  
  RBP    Exp_UID    Cell_Line    ENCODE_ACCESSION    Control_ENCODE_ACCESSION    ENCODE_Antibody_ID    Antibody    Lot_num    Status    Project  
WRN416K562ENCSR038JMEENCSR925ZRVENCAB362RRMGTX10108139812ReleasedENCODE4


  Antibody Validation  
  GeneName    Antibody_DCC_ID    Product_ID    Lot_ID    Phosphate    HepG2 Primary Validation    K562 Primary Validation    HepG2 Secondary Validation    K562 Secondary Validation  
WRNENCAB362RRMGTX10108139812Released, ENCODE3BGHLV37-87, Released, ENCODE3BGKLV38-109, Released, ENCODE3


  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
WRNK562shRNAENCSR165BCFENCSR718EWLWRN_BGKLV38-109,WRN_BGKLV38-110NT_BGKLV38-1,NT_BGKLV38-271.2,80.4ReleasedENCODE3
WRNK562shRNABGKLV38-111,BGKLV38-112BGKLV38-1,BGKLV38-243.5,17.8NotSatisfiedENCODE3
WRNK562shRNABGKLV38-113,BGKLV38-114BGKLV38-1,BGKLV38-272.1,67.7NotSatisfiedENCODE3
WRNHepG2shRNABGHLV33-41,BGHLV33-42BGHLV33-1,BGHLV33-20.0,37.0NotSatisfiedENCODE3
WRNHepG2shRNAENCSR093FHCENCSR225PRVWRN-BGHLV37-87C,WRN-BGHLV37-88Cnon-target-BGHLV37-1C,non-target-BGHLV37-2C98.1,89.6ReleasedENCODE4
WRNHepG2shRNABGHLV37-89,BGHLV37-90BGHLV37-1,BGHLV37-288.0,76.9NotSatisfiedENCODE3


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  
    WRN: Click to RBP Image Database
  • Nuclei
  • Mutually Exclusive from Nucleolus
  • Speckles
  • Variable Nuclear Intensity
  • Cytoplasm
  • Cytosolic
  • Nuclear release mitosis












    • RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela
    WRNProduct_ID: GTX101081
    Lot_ID: 39812
    Source: GeneTex
    Target Name: WRN-human    		 WRN-HEPG2.png<br>Caption: Western blot following shRNA against WRN in HepG2 whole cell lysate using WRN specific antibody. Lane 1 is a ladder, lane 2 is HepG2 non-targeting control knockdown, lane 3 and 4 are two different shRNAs against WRN. WRN protein appears as the green arrow, GAPDH serves as a control and appears in red arrow.
    		 K562_Genetex_GTX101081_39812_WRN.png<br>Caption: IP-Western Blot analysis of K562 whole cell lysate using WRN specific antibody. Lane 1 is 1% of twenty million whole cell lysate input and lane 2 is 25% of IP enrichment using rabbit normal IgG (lanes under 'IgG'). Lane 3 is 1% of twenty million whole cell lysate input and lane 4 is 10% IP enrichment using rabbit polyclonal anti-WRN antibody (lanes under 'WRN').
    		 WRN-K562.png<br>Caption: Western blot following shRNA against WRN in k562 whole cell lysate using WRN specific antibody. Lane 1 is a ladder, lane 2 is k562 non-targeting control knockdown, lane 3 and 4 are two different shRNAs against WRN. WRN protein appears as the green arrow, GAPDH serves as a control and appears in red arrow.








    RNA Targets
    • WRN protein binds to 105 RNA regions.  





    Proteins bound to RNA
    • WRN RNA is bound by 32 proteins.  






    WRN protein has 105 RNA targets:

    Only display 100 entries as example. Please click "View All" button to see all 105 entries.     

    RBP Chr Start End Strand log2(fold change) -log(p-value) Cell Line Matched Gene Matched Area
    WRNchr116229326962293324-4.467024.84095K562AHNAKCDS,intron-Distal
    WRNchr16999004999041-6.172495.99111K562LMF1intron-Distal
    WRNchr203602704036027138+5.7757211.71315K562SRCintron-Distal
    WRNchr1169076204169076227+4.9462310.33294K562ATP1B1intron-Proximal
    WRNchr194598187145981875-6.01448400.00000K562ERCC1intron-Distal
    WRNchr161880039318800442-3.611549.25274K562RP11-1035H13.3, RPS15A5'-UTR,CDS,intron-Distal,intron-Proximal
    WRNchr1569896569978-3.383277.66123K562RP5-857K21.4intron-Distal
    WRNchr67673601576736042-5.281707.69694K562IMPG1intron-Distal
    WRNchr134163490141634936-4.17672400.00000K562ELF1intron-Distal
    WRNchr145069533950695356-6.257456.80719K562SOS2intron-Distal
    WRNchr11106689666106689678-4.6967423.26818K562GUCY1A2intron-Distal
    WRNchr5134259780134259804+4.2238410.96815K562PCBD2intron-Distal
    WRNchr7149286168149286200-4.2460237.26860K562ZNF767intron-Distal
    WRNchr193080414530804169+6.172495.99111K562ZNF536intron-Distal
    WRNchr145069533550695339-6.257456.80719K562SOS2intron-Distal
    WRNchr12133451283133451360-6.2129514.98013K562CHFRintron-Distal
    WRNchr19039048790390544+4.936683.08884K562LRRC8D, RP11-302M6.4intron-Distal
    WRNchr145870665258706687-3.307404.13591K562C14orf37intron-Distal
    WRNchr11706701217067040+5.4629110.66153K562CROCCintron-Distal
    WRNchr9138901515138901562-5.225956.06646K562NACC23'-UTR,intron-Distal
    WRNchr91938019619380231-4.4218142.25450K562RPS65'-UTR,intron-Distal,intron-Proximal
    WRNchr106457361364573623-7.5269726.60226K562EGR2CDS,intron-Distal
    WRNchr139200060392000648+3.107208.33179K562MIR17HGintron-Distal
    WRNchr203739372637393810+6.518439.27808K562ACTR5intron-Distal
    WRNchr214200621642006239-6.275727.62751K562DSCAMintron-Distal
    WRNchr34573049145730527-3.01301400.00000K562LIMD1-AS1intron-Distal
    WRNchr12133450981133451089-5.9509612.52639K562CHFRintron-Distal
    WRNchr194598187545981898-5.28655400.00000K562ERCC1intron-Distal
    WRNchr1919906641990688-5.8444717.76544K562BTBD2intron-Distal,intron-Proximal
    WRNchr7149292276149292321-4.051996.67741K562ZNF767intron-Distal
    WRNchr157422266474222672+3.7208915.36456K562LOXL1intron-Distal
    WRNchr134163486041634880-3.59528400.00000K562ELF1intron-Distal
    WRNchr11109641819109641827-7.6442012.60715K562RP11-262A12.1intron-Distal
    WRNchr101893488418934939-7.6423912.22280K562RP11-139J15.7, NSUN6intron-Distal
    WRNchr10128256368128256376-7.9888548.51501K562C10orf90intron-Distal
    WRNchr111709713317097171-3.235508.00254K562RPS13CDS,intron-Distal,intron-Proximal
    WRNchr14524218145242207+3.2069636.81790K562RPS8intron-Distal
    WRNchr206259765662597672-5.8371416.86697K562ZNF512BCDS,intron-Distal
    WRNchr63195827931958283+5.658489.57899K562C4Aintron-Distal
    WRNchrX7128440371284424+6.018435.18024K562NHSL2intron-Distal
    WRNchr1781255498125588-3.3441715.65367K562LINC00324intron-Distal,intron-Proximal
    WRNchr101893483118934884-7.7681616.86709K562NSUN6, RP11-139J15.7intron-Distal
    WRNchr32395934023959365+3.282798.04978K562RPL155'-UTR,CDS,intron-Proximal
    WRNchr203602719336027257+4.699714.36176K562SRCintron-Distal
    WRNchr157422265374222657+3.7208915.36456K562LOXL1intron-Distal
    WRNchr22727373427273743+3.00087400.00000K562AGBL5intron-Distal
    WRNchr7149286159149286168-4.2460237.26860K562ZNF767intron-Distal
    WRNchr5180692667180692676+3.6172319.64530K562CTC-338M12.4, TRIM52-AS1intron-Distal
    WRNchr194598185445981857-6.10909400.00000K562ERCC1intron-Distal
    WRNchr172691950926919558-5.9462314.36638K562SPAG5, RP11-192H23.4CDS,intron-Distal,intron-Proximal
    WRNchr1781255888125619-3.6611716.96634K562LINC00324intron-Distal,intron-Proximal
    WRNchr11618885618894-6.7219141.12338K562CDHR53'-UTR,CDS,intron-Distal
    WRNchrX1618601316186062-7.9843345.14870K562RP11-431J24.2intron-Distal
    WRNchr63455519434555266-3.351487.22447K562C6orf1063'-UTR,intron-Distal
    WRNchr11618894618908-6.7219141.12338K562CDHR53'-UTR,CDS,intron-Distal
    WRNchr1816918651691878+5.373917.54178K562CTD-2015H3.2intron-Distal
    WRNchr1227087974227087980+6.3869123.19792K562ADCK3intron-Distal
    WRNchr11106689678106689688-4.6967423.26818K562GUCY1A2intron-Distal
    WRNchr221709116217091220+3.543035.68407K562TPTEP1intron-Distal
    WRNchr22727411827274135+3.5791435.08877K562AGBL5intron-Distal
    WRNchr191428077814280844-7.5478830.65426K562LPHN1intron-Distal
    WRNchr177303003173030088+3.1751625.88582K562KCTD2intron-Proximal
    WRNchr161880162818801655-3.822278.28908K562RPS15A, RP11-1035H13.35'-UTR,intron-Distal,intron-Proximal
    WRNchr222011104620111099+3.348505.39402K562RANBP1intron-Distal
    WRNchr124815369748153719+6.076175.18024K562SLC48A1intron-Distal
    WRNchr11109641815109641819-7.6442012.60715K562RP11-262A12.1intron-Distal
    WRNchr108107494381075027+6.644208.54153K562ZMIZ13'-UTR
    WRNchr7103029405103029414-6.636956.80719K562SLC26A5intron-Distal,intron-Proximal
    WRNchr172691955826919600-4.6119310.56340K562RP11-192H23.4, SPAG5CDS,intron-Distal,intron-Proximal
    WRNchrX1618600016186013-8.2109038.82722K562RP11-431J24.2intron-Distal
    WRNchr7103029414103029425-6.636956.80719K562SLC26A5intron-Distal,intron-Proximal
    WRNchr194598185745981871-6.01448400.00000K562ERCC1intron-Distal
    WRNchr43946005439460061-3.474535.72750K562RPL95'-UTR,CDS,intron-Distal,intron-Proximal
    WRNchr10128256376128256388-7.9888548.51501K562C10orf90intron-Distal
    WRNchr5180692676180692692+3.6172319.64530K562CTC-338M12.4, TRIM52-AS1intron-Distal
    WRNchr43946051039460532-3.211495.18766K562RPL95'-UTR,CDS,intron-Distal,intron-Proximal
    WRNchr134163488041634901-3.66861400.00000K562ELF1intron-Distal
    WRNchr1151175493151175544+5.907236.72027K562PIP5K1Aintron-Distal
    WRNchr107979362079793665+3.1671719.94734K562RPS245'-UTR,CDS,intron-Proximal
    WRNchr1219482541948280-3.182226.29454K562CACNA2D4intron-Distal
    WRNchr1227087982227087995+6.3869123.19792K562ADCK3intron-Distal
    WRNchr9140610785140610834+5.955665.81702K562EHMT1intron-Distal
    WRNchr154549260845492645-3.491845.40820K562SHFintron-Distal
    WRNchr11109641827109641835-7.6442012.60715K562RP11-262A12.1intron-Distal
    WRNchr117241443972414444-4.3413412.83293K562ARAP15'-UTR,intron-Distal
    WRNchr19039054490390634+5.9462313.16997K562LRRC8D, RP11-302M6.4intron-Distal
    WRNchr34573047845730489-3.09870400.00000K562LIMD1-AS1intron-Distal
    WRNchr117241444472414460-4.3616612.83293K562ARAP15'-UTR,intron-Distal,intron-Proximal
    WRNchr194598189845981921-4.96275400.00000K562ERCC1intron-Distal
    WRNchr206259765362597656-5.8371416.86697K562ZNF512BCDS,intron-Distal
    WRNchr117511571475115731+3.2811610.51841K562RPS33'-UTR,CDS,intron-Proximal
    WRNchr106457362464573635-7.5269726.60226K562EGR2CDS,intron-Distal
    WRNchrX1618596416186000-6.6513814.18715K562RP11-431J24.2intron-Distal
    WRNchr7139025476139025500+3.20945400.00000K562C7orf55-LUC7L2, C7orf55intron-Distal
    WRNchr11941774941833+6.833458.54153K562AP2A2intron-Distal
    WRNchr156607007666070136-6.1369514.98391K562DENND4Aintron-Distal
    WRNchr139200319092003217+5.386917.80965K562MIR17HGintron-Distal
    WRNchr1194818959481948-5.636958.69158K562AC132192.1CDS
    WRNchr1827169892717021+6.873919.45782K562SMCHD1intron-Distal
    WRNchr29753559297535711-3.638217.94190K562SEMA4C5'-UTR,intron-Distal,intron-Proximal




    32 proteins are bound to WRN RNA:

    Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
    chr83103071731030847+3'-UTR4.121384.20072K562IGF2BP1
    chr83089136730891433+5'-UTR4.222284.35343K562SRSF1
    chr83089138530891448+5'-UTR3.9834019.73755K562ZNF622
    chr83089138530891428+5'-UTR3.980766.98960K562RBM15
    chr83089132530891386+5'-UTR3.544875.03370HepG2NCBP2
    chr83089139030891433+5'-UTR3.858185.39661K562GEMIN5
    chr83091584830915894+5'-UTR,intron-Proximal5.159486.47067K562SF3B4
    chr83089142830891463+5'-UTR5.284959.68097K562RBM15
    chr83099910630999215+CDS,intron-Proximal4.573359.81400K562EFTUD2
    chr83094640530946452+CDS,intron-Proximal5.1712417.92802K562ZNF622
    chr83092466630924716+CDS,intron-Proximal4.872963.70131HepG2PRPF8
    chr83094529730945324+CDS3.337624.74886HepG2BCLAF1
    chr83094640530946479+CDS,intron-Proximal4.366156.08299HepG2PPIG
    chr83099927130999290+CDS4.824217.50842K562DDX24
    chr83094798130948026+CDS,intron-Distal4.0830514.75114K562ZNF622
    chr83093842230938453+CDS4.2563212.39089K562ZNF622
    chr83092193430921959+CDS,intron-Proximal3.998023.33054K562U2AF1
    chr83101225131012269+CDS4.104526.81381K562DDX24
    chr83094540730945439+CDS,intron-Proximal4.474704.38106HepG2PPIG
    chr83093871830938789+CDS3.1687117.98586K562UCHL5
    chr83094934330949404+CDS,intron-Proximal4.1632518.39855K562DDX24
    chr83094934530949393+CDS,intron-Proximal3.5461619.39032K562ZNF622
    chr83092582030925868+CDS,intron-Proximal3.428163.47285K562PRPF8
    chr83094537230945393+CDS3.354507.15230K562UCHL5
    chr83095835530958471+CDS,intron-Proximal4.1542114.57163K562U2AF2
    chr83094641030946437+CDS3.612535.56491HepG2BCLAF1
    chr83092467730924747+CDS,intron-Proximal3.078693.38150K562KHSRP
    chr83092468730924735+CDS,intron-Proximal3.791915.58816K562PRPF8
    chr83092253730922579+CDS5.8488111.17302HepG2BCLAF1
    chr83094640530946465+CDS,intron-Proximal3.9621520.81733K562UCHL5
    chr83094542030945436+CDS3.528504.40995K562GRWD1
    chr83094542030945434+CDS4.140119.43617K562UCHL5
    chr83094800230948038+CDS,intron-Distal4.414084.83285K562GRWD1
    chr83094537330945432+CDS4.9419223.17584K562ZNF622
    chr83093860230938735+CDS3.949706.60786K562CPSF6
    chr83094798030948037+CDS,intron-Distal,intron-Proximal4.2239211.11870HepG2BCLAF1
    chr83100014431000174+CDS3.980816.88148K562BUD13
    chr83093871930938786+CDS3.153796.73181K562HLTF
    chr83095835230958422+CDS,intron-Proximal3.369335.42523K562U2AF1
    chr83093868630938766+CDS4.1368124.52185K562ZNF622
    chr83098988030989905+CDS,intron-Proximal5.042327.04013HepG2BCLAF1
    chr83094798030948048+CDS,intron-Distal,intron-Proximal3.6915410.65400K562DDX24
    chr83094539230945437+CDS,intron-Proximal3.792403.14726K562SRSF7
    chr83092454830924586+CDS,intron-Proximal3.192828.91678K562UCHL5
    chr83094842030948458+CDS3.161175.53494HepG2BCLAF1
    chr83095835130958403+CDS,intron-Proximal5.569207.41223K562SF3B4
    chr83092253330922579+CDS3.280669.58912K562ZNF622
    chr83094646530946481+CDS3.385777.80035K562UCHL5
    chr83097770530977760+CDS,intron-Proximal5.0391916.10548K562SF3B4
    chr83094839730948458+CDS4.3003716.44980K562DDX24
    chr83095427830954341+CDS,intron-Proximal3.5297211.75242K562BUD13
    chr83091663130916680+CDS,intron-Proximal3.445566.69182K562AQR
    chr83095428830954408+CDS,intron-Proximal3.132036.32831K562PRPF8
    chr83095436430954409+CDS,intron-Proximal3.344186.16312K562AQR
    chr83093859430938686+CDS4.3679822.84829K562ZNF622
    chr83093367630933722+CDS,intron-Proximal4.418676.24021K562U2AF2
    chr83097768030977772+CDS,intron-Proximal4.3698920.03654K562KHSRP
    chr83093871730938791+CDS4.834809.74753HepG2BCLAF1
    chr83097395830973995+CDS3.562648.93089K562ZNF622
    chr83093871730938762+CDS3.348753.11443K562MTPAP
    chr83094539330945420+CDS4.1615012.99675K562UCHL5
    chr83094646930946481+CDS3.511697.86771K562ZNF622
    chr83091597930916032+CDS3.3244315.87834K562ZNF622
    chr83095430330954399+CDS,intron-Proximal3.068316.45810K562EFTUD2
    chr83093858830938718+CDS3.9330928.89493K562UCHL5
    chr83092243030922487+CDS,intron-Proximal3.264433.75792K562U2AF2
    chr83094844930948458+CDS3.2683212.23735K562ZNF622
    chr83094640530946455+CDS,intron-Proximal3.388775.80673K562GRWD1
    chr83094936130949405+CDS3.039037.94218K562BUD13
    chr83094802630948044+CDS,intron-Distal4.3148810.03782K562ZNF622
    chr83101488231014897+CDS,intron-Proximal4.057966.81381K562DDX24
    chr83094935430949382+CDS3.716857.23562HepG2BCLAF1
    chr83094640530946451+CDS,intron-Proximal3.9670911.16701K562DDX24
    chr83093373530933782+CDS4.3982618.33672K562ZNF622
    chr83100014131000162+CDS,intron-Proximal5.919197.72885K562DDX24
    chr83094797930948048+CDS,intron-Distal,intron-Proximal3.816385.73400HepG2PPIG
    chr83100063031000723+intron-Distal4.638098.89446K562HNRNPL
    chr83097686130976898+intron-Distal4.667125.07733HepG2PTBP1
    chr83097665030976707+intron-Distal4.9531862.81887K562PTBP1
    chr83092773730927799+intron-Distal4.823894.79708HepG2U2AF2
    chr83092266330922687+intron-Distal,intron-Proximal3.337456.60316K562KHSRP
    chr83096016730960263+intron-Distal3.852613.22972K562TARDBP
    chr83091943130919517+intron-Distal3.997566.43962K562MATR3
    chr83093249730932537+intron-Distal3.570085.85289K562EXOSC5
    chr83094944530949521+intron-Distal,intron-Proximal5.5260711.38968K562KHSRP
    chr83097641630976477+intron-Distal3.083038.54023K562KHSRP
    chr83102198331022055+intron-Distal3.578403.02234K562KHSRP
    chr83091613330916196+intron-Distal,intron-Proximal3.619865.17284K562TIA1
    chr83092551830925565+intron-Distal3.063143.76473K562KHSRP
    chr83097682930976909+intron-Distal4.089959.86758K562MATR3
    chr83097684030976906+intron-Distal5.0994723.82345K562PTBP1
    chr83093283030932882+intron-Distal3.597306.13002K562EXOSC5
    chr83095465430954737+intron-Distal3.498326.57673K562KHSRP
    chr83091574330915837+intron-Distal,intron-Proximal4.140657.69621K562KHSRP
    chr83099008330990143+intron-Distal,intron-Proximal4.884435.82778K562PRPF8
    chr83101373731013917+intron-Distal3.056295.65129K562KHSRP
    chr83097663530976705+intron-Distal5.4805729.30575HepG2PTBP1
    chr83100410531004177+intron-Distal4.196974.08501K562U2AF2
    chr83097707230977104+intron-Distal3.7471610.91503K562KHSRP
    chr83091994030919999+intron-Distal3.960275.54624K562U2AF1
    chr83097665530976749+intron-Distal3.412236.40322HepG2MATR3
    chr83100056731000627+intron-Distal4.393587.34799K562HNRNPL
    chr83097671930976754+intron-Distal6.9053860.20258K562PTBP1
    chr83097670530976749+intron-Distal7.2867836.96902HepG2PTBP1
    chr83089698430897118+intron-Distal4.168326.21862K562MATR3
    chr83092438430924455+intron-Distal,intron-Proximal3.373784.56635K562KHSRP
    chr83101070231010845+intron-Distal3.667605.80260K562HNRNPL
    chr83102633131026447+intron-Distal4.906788.94695K562KHSRP
    chr83091854630918615+intron-Distal3.202095.15820K562MATR3
    chr83097693830977038+intron-Distal3.317307.47778K562MATR3
    chr83097670730976719+intron-Distal5.7467668.23125K562PTBP1
    chr83100473331004783+intron-Distal,intron-Proximal3.341543.28806K562KHSRP
    chr83097671230976755+intron-Distal3.665163.77680K562TIA1
    chr83096239830962453+intron-Distal4.783776.09831K562HNRNPM
    chr83089683030896893+intron-Distal4.117033.45817K562MATR3
    chr83091995030920006+intron-Distal3.310998.00766K562U2AF2
    chr83100430931004511+intron-Distal,intron-Proximal4.3725419.11290K562KHSRP
    chr83097662830976754+intron-Distal4.6877529.48948K562MATR3
    chr83097710430977129+intron-Distal5.5188411.84112K562KHSRP
    chr83100064531000671+intron-Distal3.943655.10278K562AGGF1
    chr83097722430977281+intron-Distal3.259139.72619K562KHSRP
    chr83097702930977056+intron-Distal4.055127.55880K562PTBP1
    chr83100131431001389+intron-Distal4.166267.69621K562KHSRP
    chr83099656530996670+intron-Distal3.476255.34873K562KHSRP
    chr83099527330995364+intron-Distal4.505215.79092K562TARDBP
    chr83100410531004176+intron-Distal3.752883.16095HepG2U2AF2
    chr83094821430948278+intron-Distal,intron-Proximal3.720303.02234K562KHSRP
    chr83091988730919931+intron-Distal4.345476.59856K562SF3B4
    chr83097663130976650+intron-Distal4.189128.75579K562PTBP1
    chr83094944630949523+intron-Distal,intron-Proximal4.399308.91093K562PRPF8
    chr83094952130949581+intron-Distal5.5951110.47957K562KHSRP
    chr83089675330896803+intron-Distal3.997563.33944K562MATR3
    chr83093282630932897+intron-Distal3.609137.51388K562HNRNPM
    chr83090349230903640+intron-Distal3.9827315.57980K562KHSRP
    chr83092069130920790+intron-Distal3.572747.83495K562KHSRP
    chr83089737030897448+intron-Distal3.382557.63715K562KHSRP
    chr83090947530909607+intron-Distal3.085196.93011K562KHSRP
    chr83092525630925325+intron-Distal5.248459.81815K562KHSRP
    chr83091680330916895+intron-Distal,intron-Proximal3.204387.50498K562KHSRP
    chr83097763730977678+intron-Distal,intron-Proximal3.260998.24998K562KHSRP
    chr83095023530950310+intron-Distal3.770933.59673K562HNRNPL
    chr83099422330994291+intron-Distal4.409935.18738K562TARDBP
    chr83093254430932625+intron-Distal3.8849310.22385K562HNRNPM
    chr83092196630922071+intron-Distal,intron-Proximal3.834623.31110K562TIA1
    chr83092593130926042+intron-Distal,intron-Proximal4.354429.48359K562PRPF8
    chr83092519630925251+intron-Distal3.631305.32884K562KHSRP
    chr83096282530962885+intron-Distal3.956073.45817K562MATR3
    chr83092593430925966+intron-Distal,intron-Proximal3.765045.32884K562KHSRP
    chr83095413830954204+intron-Distal,intron-Proximal4.570526.07567K562KHSRP
    chr83098223730982320+intron-Distal,intron-Proximal3.7579411.99390K562KHSRP
    chr83095440930954466+intron-Proximal4.093276.19377K562KHSRP
    chr83089150730891545+intron-Proximal4.218989.15310K562TIA1
    chr83094944230949510+intron-Proximal3.563584.35027K562EFTUD2
    chr83092448630924543+intron-Proximal4.716818.05832K562SF3B4
    chr83092261930922663+intron-Proximal3.296734.14287K562KHSRP
    chr83089149330891544+intron-Proximal3.238343.18246K562PRPF8
    chr83095831730958348+intron-Proximal5.107254.90235K562SF3B4
    chr83093361030933643+intron-Proximal3.584265.14864K562KHSRP
    chr83091657230916620+intron-Proximal3.780675.36888K562KHSRP
    chr83097796430978031+intron-Proximal4.105786.31048K562RBM22
    chr83094543930945485+intron-Proximal5.319796.75320K562AQR
    chr83097406030974123+intron-Proximal4.988348.58833K562TIA1
    chr83093364330933662+intron-Proximal3.120293.28806K562KHSRP
    chr83092572230925764+intron-Proximal4.869655.58150K562SF3B4
    chr83100802831008071+intron-Proximal4.238343.89565K562PRPF8
    chr83091679130916864+intron-Proximal5.1840110.29472K562TIA1
    chr83093363830933670+intron-Proximal5.896878.42776K562SF3B4
    ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




    No autoregularoty interactions between protein WRN and its RNA.



    Diffrential Expression
    • 1,510 differentially expressed genes after Knockdown/Knockout WRN protein.  





    • 71 RBPs can affect the levels of WRN.  







    1,510 differentially expressed genes after Knockdown/Knockout WRN protein :

    Only display 100 entries as example. Please click "View All" button to see all 1,510 entries.     

    Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
    LAS1LENSG00000001497.124169.204305083.29980-0.286002.802401.50090K562WRN
    LAP3ENSG00000002549.82852.859903473.28310-0.283902.797901.49780K562WRN
    CFLARENSG00000003402.153102.836303792.66880-0.289602.824101.51620K562WRN
    CDC27ENSG00000004897.74093.823005526.46910-0.432906.010904.11010K562WRN
    SLC4A1ENSG00000004939.92439.15290405.625802.5881017.7900015.01350K562WRN
    SLC25A5ENSG00000005022.515701.2886019008.60480-0.275802.998801.65140K562WRN
    ACSM3ENSG00000005187.74804.717402917.621300.719604.281202.66570K562WRN
    FAM214BENSG00000005238.15409.78710298.526400.456902.812101.50660K562WRN
    PRKAR2BENSG00000005249.87547.8036011051.31080-0.5501010.067907.75140K562WRN
    CREBBPENSG00000005339.82168.210501738.140600.318903.048101.68650K562WRN
    WDR54ENSG00000005448.12422.18240289.539500.544003.371201.93760K562WRN
    ZFXENSG00000005889.111186.66560932.932000.347002.812201.50660K562WRN
    ITGA2BENSG00000005961.13964.04270719.976300.421002.788601.49220K562WRN
    GDE1ENSG00000006007.72779.721302169.963700.357203.811602.28640K562WRN
    ETV1ENSG00000006468.9394.99220602.86990-0.610005.465903.65360K562WRN
    CCL26ENSG00000006606.417.5267044.24030-1.335802.576301.33600K562WRN
    ARSDENSG00000006756.1124.496604.703202.380803.269301.85370K562WRN
    CCDC124ENSG00000007080.61435.616101776.88280-0.307702.668901.40690K562WRN
    PAFAH1B1ENSG00000007168.84395.109503627.573600.276802.659801.39900K562WRN
    MATKENSG00000007264.9584.08940820.17850-0.489704.296502.67750K562WRN
    TKTL1ENSG00000007350.12161.8031056.951001.506309.123006.86530K562WRN
    RHBDF1ENSG00000007384.11820.93640481.742800.768904.557402.89330K562WRN
    CACNA2D2ENSG00000007402.786.1194039.408801.127703.594002.11190K562WRN
    MYLIPENSG00000007944.102446.202401924.129700.346203.047601.68650K562WRN
    SYN1ENSG00000008056.858.0360016.906901.779204.896903.17560K562WRN
    JARID2ENSG00000008083.93062.625002435.039400.330702.718401.44320K562WRN
    MGST1ENSG00000008394.8533.426401044.10210-0.968908.650406.44720K562WRN
    MAPK8IP2ENSG00000008735.1045.091309.152802.300505.259503.47690K562WRN
    CSDE1ENSG00000009307.1123564.8107029134.24340-0.306103.571802.09330K562WRN
    TENM1ENSG00000009694.92182.349801578.615500.467105.890704.00700K562WRN
    VTA1ENSG00000009844.112363.546703105.79600-0.394004.753203.05270K562WRN
    IDSENSG00000010404.131617.679701140.850200.503706.130604.20630K562WRN
    ABHD5ENSG00000011198.33843.017101893.783001.0209027.2159023.84730K562WRN
    PIK3C2AENSG00000011405.93323.847702560.891700.376103.476002.02030K562WRN
    ANLNENSG00000011426.62751.175403611.96260-0.392704.441702.79610K562WRN
    QPCTLENSG00000011478.7380.05730585.54360-0.623605.579603.74540K562WRN
    CEP68ENSG00000011523.9902.95980673.370300.423203.696902.19650K562WRN
    MAP4K3ENSG00000011566.101484.557301070.218400.472005.229203.45080K562WRN
    TMEM159ENSG00000011638.6613.05440412.390800.571904.928103.20320K562WRN
    PGM3ENSG00000013375.115657.381304045.779400.483603.250201.83930K562WRN
    SLC30A9ENSG00000014824.92883.992303979.38380-0.464506.332604.37590K562WRN
    MTMR11ENSG00000014914.1586.7899043.730200.988803.020801.66810K562WRN
    TTC27ENSG00000018699.72002.612702646.52100-0.402204.696903.00790K562WRN
    PRDM11ENSG00000019485.837.8678013.220801.518102.745401.46220K562WRN
    SERPINB1ENSG00000021355.82505.861603186.21310-0.346503.709002.20590K562WRN
    NLRP2ENSG00000022556.111455.724901866.15830-0.358303.404801.96330K562WRN
    SNAPC1ENSG00000023608.4359.21860554.80580-0.627104.441102.79610K562WRN
    DEF6ENSG00000023892.9780.09070994.58310-0.350402.677901.41470K562WRN
    PLEKHO1ENSG00000023902.9370.51680255.609700.535503.198301.79820K562WRN
    GCLMENSG00000023909.54571.848603447.859200.407004.935603.20810K562WRN
    VIMENSG00000026025.97654.9103010018.04310-0.388105.169303.40570K562WRN
    RTEL1-TNFRSF6BENSG00000026036.16605.21030800.93720-0.404303.186101.79030K562WRN
    CD44ENSG00000026508.12279.00290154.284000.854605.874703.99620K562WRN
    MIPEPENSG00000027001.7317.38730488.41720-0.621905.082403.32950K562WRN
    PRKCHENSG00000027075.9102.14180188.18850-0.881604.562502.89680K562WRN
    SH2D2AENSG00000027869.7642.28460822.83210-0.357402.582901.34090K562WRN
    NUP160ENSG00000030066.95988.557807498.20240-0.324303.735502.22590K562WRN
    FAM13BENSG00000031003.61748.450101127.591800.632709.162806.90200K562WRN
    TSSC1ENSG00000032389.8840.624101061.97910-0.337202.765201.47710K562WRN
    IFT88ENSG00000032742.13411.15880543.34040-0.402202.604901.35840K562WRN
    CHPF2ENSG00000033100.101091.25180819.189700.413603.782402.26390K562WRN
    RNF19AENSG00000034677.72051.506101558.375900.396504.325702.70270K562WRN
    NSUN2ENSG00000037474.104740.089007734.13490-0.706305.600003.75820K562WRN
    RAB27BENSG00000041353.5223.25300414.00230-0.891008.029905.89270K562WRN
    PSMA4ENSG00000041357.117024.572209190.11260-0.387705.201603.43410K562WRN
    DSG2ENSG00000046604.85213.219806384.64860-0.292403.032201.67570K562WRN
    WWC3ENSG00000047644.13235.45620126.193300.899705.563803.73250K562WRN
    CC2D2AENSG00000048342.11139.6945078.097900.838803.317901.89330K562WRN
    SNX29ENSG00000048471.9703.02370493.192400.511304.470902.81980K562WRN
    VAMP3ENSG00000049245.82627.931802089.008700.331003.309601.88730K562WRN
    NEDD4LENSG00000049759.121003.140101431.63800-0.513105.879103.99860K562WRN
    JKAMPENSG00000050130.13589.96980837.72370-0.505804.751003.05200K562WRN
    PIK3CBENSG00000051382.44633.750503670.065100.336303.803402.28100K562WRN
    PTPRNENSG00000054356.9189.1852059.028701.6802012.062309.58680K562WRN
    ATP9AENSG00000054793.966.5294027.884101.254502.591401.34730K562WRN
    FAM168AENSG00000054965.6701.11420516.457800.440903.509102.04710K562WRN
    KCNH2ENSG00000055118.109539.9784012617.03280-0.403303.754502.24140K562WRN
    EIF2AK2ENSG00000055332.122647.491102176.594300.282502.567901.32940K562WRN
    PKP2ENSG00000057294.9102.59900198.82150-0.954505.295503.50770K562WRN
    ATG5ENSG00000057663.81718.568602362.03500-0.458803.641002.14750K562WRN
    PPP1R12AENSG00000058272.113336.468904701.16920-0.494703.189301.79300K562WRN
    ATP2B4ENSG00000058668.101319.768902320.30810-0.8140015.3036012.69980K562WRN
    ZC3H11AENSG00000058673.1112877.4646010612.877100.278903.044001.68360K562WRN
    PET112ENSG00000059691.7812.879101041.16700-0.357102.861401.54550K562WRN
    SLC2A3ENSG00000059804.116076.9274010208.68530-0.7484013.3645010.84660K562WRN
    WNK1ENSG00000060237.128590.387907082.974500.278303.038101.68010K562WRN
    HDAC7ENSG00000061273.132894.529905550.31660-0.9392024.4624021.30770K562WRN
    NCKAP1ENSG00000061676.1010605.724708097.408900.389205.285203.49850K562WRN
    DGAT2ENSG00000062282.10105.4750052.714101.000503.596602.11350K562WRN
    ASUNENSG00000064102.102787.385103419.79960-0.295002.884001.56210K562WRN
    TM7SF3ENSG00000064115.61076.620301350.59230-0.327102.753001.46780K562WRN
    TSPAN32ENSG00000064201.11106.2569060.552700.811202.635401.38060K562WRN
    TAF2ENSG00000064313.72118.329402742.83080-0.372704.112102.53330K562WRN
    CNN2ENSG00000064666.103352.593104121.14780-0.297803.023001.66950K562WRN
    ABCA7ENSG00000064687.82650.630204146.93540-0.6457011.571909.13960K562WRN
    FAR2ENSG00000064763.6275.29510379.59700-0.463502.584601.34230K562WRN
    WDR3ENSG00000065183.113930.804205202.95260-0.404503.565702.08870K562WRN
    PDIA5ENSG00000065485.131221.66900931.974700.390402.795201.49650K562WRN
    SEC61A2ENSG00000065665.16229.53340140.894200.704002.906801.58030K562WRN
    ZBTB11ENSG00000066422.42361.106703358.63720-0.508404.251602.64160K562WRN
    Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

    *: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
    **: "-log(0)" was displayed as "99999.99999".





    71 RBPs can affect the gene expression of WRN :

    Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
    WRNENSG00000165392.5495.39380619.65790-0.322902.448101.72170HepG2AKAP8L
    WRNENSG00000165392.5369.30420529.05440-0.518603.116602.29830HepG2CIRBP
    WRNENSG00000165392.5481.19760616.62200-0.357803.171802.46970HepG2CKAP4
    WRNENSG00000165392.5621.27240766.20570-0.302502.758702.01790HepG2DAZAP1
    WRNENSG00000165392.5472.45480644.71130-0.448502.630902.01930HepG2DDX3X
    WRNENSG00000165392.5329.69890513.98980-0.640603.107602.04330HepG2DDX5
    WRNENSG00000165392.5434.08490590.08500-0.442903.779103.01120HepG2DKC1
    WRNENSG00000165392.5378.68290478.68990-0.338102.524401.89580HepG2DNAJC2
    WRNENSG00000165392.5769.22390572.827800.425202.008101.41640HepG2EIF4B
    WRNENSG00000165392.5439.45240292.866500.585403.929803.00030HepG2FUBP3
    WRNENSG00000165392.5438.95680605.57640-0.464202.325701.39540HepG2GNB2L1
    WRNENSG00000165392.5319.03590487.55100-0.611804.423903.63190HepG2HNRNPA1
    WRNENSG00000165392.5250.47560542.32030-1.1145012.2295010.86130HepG2HNRNPC
    WRNENSG00000165392.5764.20130557.487500.454903.193002.44440HepG2HNRNPK
    WRNENSG00000165392.5550.60910697.95370-0.342103.211502.48940HepG2HNRNPL
    WRNENSG00000165392.5433.62460538.73410-0.313102.186401.64070HepG2HNRNPU
    WRNENSG00000165392.5481.44980732.81810-0.606103.943102.94790HepG2LARP4
    WRNENSG00000165392.5466.36300611.19680-0.390202.033601.48670HepG2NCBP2
    WRNENSG00000165392.5368.08380725.26620-0.9785012.7485011.59430HepG2PUF60
    WRNENSG00000165392.5361.08760628.22680-0.7989011.9174010.79250HepG2PUS1
    WRNENSG00000165392.5787.49370559.618600.492704.640303.86240HepG2QKI
    WRNENSG00000165392.51079.73730816.702700.402703.145602.60230HepG2RBM22
    WRNENSG00000165392.5386.80050580.79970-0.586503.375502.20360HepG2RCC2
    WRNENSG00000165392.5683.63040535.586500.352002.802202.18190HepG2RECQL
    WRNENSG00000165392.5439.77360659.67390-0.585004.074703.11170HepG2RPS2
    WRNENSG00000165392.5460.63970559.47200-0.280401.980501.42160HepG2SMN1
    WRNENSG00000165392.51455.79060922.414100.6582014.2476013.34620HepG2SRFBP1
    WRNENSG00000165392.5792.14440561.524000.496305.451704.84460HepG2SRSF1
    WRNENSG00000165392.5584.57200716.09610-0.292802.223801.65560HepG2SRSF5
    WRNENSG00000165392.5659.84470456.829300.530406.031505.27270HepG2SRSF9
    WRNENSG00000165392.5576.07610800.83630-0.475205.670204.98670HepG2SSB
    WRNENSG00000165392.5957.60820504.718400.9239016.6909015.48040HepG2TAF15
    WRNENSG00000165392.5643.64030463.768800.472703.864502.88510HepG2TIA1
    WRNENSG00000165392.5203.55320523.44330-1.3626020.4703019.34190HepG2TIAL1
    WRNENSG00000165392.5388.49030528.16280-0.443103.867903.22350HepG2TRIM56
    WRNENSG00000165392.5301.75520629.23250-1.060203.187702.12700HepG2U2AF2
    WRNENSG00000165392.5270.79240426.16540-0.654202.766101.76230HepG2UPF2
    WRNENSG00000165392.5366.72750596.81330-0.702608.482807.52680HepG2UTP3
    WRNENSG00000165392.5292.98440458.10660-0.644903.801402.96080HepG2XRN2
    WRNENSG00000165392.54009.984103177.782400.335503.064501.76930K562ABCF1
    WRNENSG00000165392.52258.713603034.32830-0.425904.812203.42740K562AKAP8
    WRNENSG00000165392.52724.782603300.08090-0.276402.837001.64310K562CCDC124
    WRNENSG00000165392.58462.616506305.799100.424307.444305.86710K562CELF1
    WRNENSG00000165392.51421.577302033.60520-0.516506.949705.19940K562DDX3X
    WRNENSG00000165392.52643.208903092.02190-0.226302.535901.70170K562DKC1
    WRNENSG00000165392.51338.652902104.94240-0.653008.184206.53980K562EFTUD2
    WRNENSG00000165392.51650.177202895.69500-0.8113020.1569018.47960K562EIF2S2
    WRNENSG00000165392.51532.334602253.82980-0.556604.914403.48890K562EIF3D
    WRNENSG00000165392.51556.060702022.06000-0.377902.872402.00100K562FMR1
    WRNENSG00000165392.51874.946602209.54000-0.236902.462001.88460K562FXR1
    WRNENSG00000165392.53615.786102339.989900.627705.637604.54720K562G3BP2
    WRNENSG00000165392.53062.210302323.227400.398306.235004.56280K562GLRX3
    WRNENSG00000165392.51518.985701896.98770-0.320602.083901.39110K562GPKOW
    WRNENSG00000165392.52392.064703859.06200-0.690008.401007.07110K562GRSF1
    WRNENSG00000165392.53385.071902605.319600.377603.920002.64370K562HNRNPA1
    WRNENSG00000165392.51100.465101815.95390-0.7226011.7335010.57850K562HNRNPC
    WRNENSG00000165392.51249.732501879.03850-0.588405.687904.29010K562HNRNPM
    WRNENSG00000165392.52094.170803097.09770-0.564507.283506.00930K562HSPD1
    WRNENSG00000165392.52434.951202918.99250-0.261602.323701.36720K562MAK16
    WRNENSG00000165392.52814.729403416.09300-0.279402.536701.67180K562MBNL1
    WRNENSG00000165392.53059.085302442.571700.324605.894604.74630K562MTPAP
    WRNENSG00000165392.51741.760002121.54730-0.284602.701301.48760K562NCBP2
    WRNENSG00000165392.57061.087105609.622600.331903.313901.66400K562NOL12
    WRNENSG00000165392.51856.488802428.39670-0.387403.932602.76160K562PCBP2
    WRNENSG00000165392.52182.406401821.713500.260502.316201.58380K562POLR2G
    WRNENSG00000165392.51917.482902593.37000-0.435604.454303.37770K562PPIG
    WRNENSG00000165392.51132.930802048.34940-0.8544013.1309011.48760K562PRPF8
    WRNENSG00000165392.51139.637901628.20980-0.514705.256903.95620K562PSIP1
    WRNENSG00000165392.51965.379802651.41130-0.432005.608804.69180K562PTBP1
    WRNENSG00000165392.53820.394005595.46110-0.550508.555807.11140K562PUF60
    WRNENSG00000165392.54080.455705831.43740-0.5151012.4589010.43250K562PUM2
    WRNENSG00000165392.5980.626401485.61190-0.599307.999606.31630K562RCC2
    WRNENSG00000165392.53289.278702743.614200.261604.710803.52910K562SRPK2
    WRNENSG00000165392.51517.705501845.42450-0.282102.326001.37490K562SRSF4
    WRNENSG00000165392.54138.129502997.208100.465305.350803.42370K562SSRP1
    WRNENSG00000165392.52071.069902537.59680-0.293102.853602.02060K562TIA1
    WRNENSG00000165392.52225.503202877.61740-0.370707.069605.98040K562UPF1
    WRNENSG00000165392.53358.716702560.496500.391409.089007.64800K562WDR43
    WRNENSG00000165392.53665.451504794.02070-0.387204.577602.90800K562WRN
    Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

    *: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
    **: "-log(0)" was displayed as "99999.99999".





    19 alternative splicing events after Knockdown/Knockout WRN protein :

    Only display 100 entries as example. Please click "View All" button to see all 19 entries.     

    Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
    SERPS24ENSG00000138326.14chr10+7979996179799983797969517979706279800372798004550.087000.000000.00000includedK562WRN
    SENSFL1CENSG00000088833.13chr20-1443979144408614388441438919144497314450710.073000.000000.00011includedK562WRN
    SEMYBENSG00000118513.14chr6+1355206631355207191355200451355201881355212221355213370.057000.000010.04178includedK562WRN
    SERPL22ENSG00000116251.5chr1-6253006625310862466346246876625771162578160.320000.000030.07910includedK562WRN
    SELYRM5ENSG00000205707.6chr12+2535665825356766253482052534827125356853253569410.065000.000010.04171includedK562WRN
    SESYPENSG00000102003.6chrX-4905062249050818490497284904992049055426490554920.401000.000020.05552includedK562WRN
    SESRRM1ENSG00000133226.12chr1+2497356924973699249731172497328024975349249755200.149000.000000.00049includedK562WRN
    SERPLP0ENSG00000089157.11chr12-1206366561206367041206351241206352651206369201206370080.094000.000000.00007includedK562WRN
    SERPL27ENSG00000131469.8chr17+4115076541150842411504524115048841151949411521190.090000.000010.02846includedK562WRN
    SEVEGFAENSG00000112715.16chr6+437484684374854043746625437466554374969243749824-0.084000.000030.07147excludedK562WRN
    SECDK10ENSG00000185324.17chr16+897556598975573289753113897531678975696089757032-0.126000.000000.02016excludedK562WRN
    SESRRM2ENSG00000167978.12chr16+281850528186002817722281826228189972819249-0.077000.000000.00193excludedK562WRN
    SESUGT1ENSG00000165416.10chr13+532356095323570553233313532333845323678353236837-0.132000.000020.05637excludedK562WRN
    SEYIF1BENSG00000167645.12chr19-388060643880617038800056388002833880650838806582-0.123000.000010.03726excludedK562WRN
    SESBF1ENSG00000100241.16chr22-508954625089554050894920508951025089768350897821-0.317000.000010.04178excludedK562WRN
    SESPAG5ENSG00000076382.12chr17-269134422691351726913107269132002691871526918890-0.069000.000020.05552excludedK562WRN
    MXEPPP2R5CENSG00000078304.15chr14+1022523541022525201022762491022763731022292411022293071023230221023232220.054000.000000.004611includedK562WRN
    MXEPAQR3ENSG00000163291.10chr4-7984329479843575798450107984510179841687798418357984767479847872-0.052000.000020.066332includedK562WRN
    MXESSX1ENSG00000126752.7chrX+4811665648116745481180114811806648114751481148674812120048121250-0.119000.000020.066332includedK562WRN





    11 RBPs can affect the splicing of WRN :

    Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
    SEWRNENSG00000165392.5chr8+309479803094804830946405309464813094834930948458-0.306000.000000.00000excludedK562SF3B4
    SEWRNENSG00000165392.5chr8+309992353099929130998945309991163100014131000217-0.075000.007310.06341excludedK562AQR
    SEWRNENSG00000165392.5chr8+309479803094804830946405309464813094834930948458-0.077000.012210.09516excludedK562AQR
    SEWRNENSG00000165392.5chr8+309479803094804830946405309464813094834930948458-0.192000.000010.00035excludedK562U2AF1
    SEWRNENSG00000165392.5chr8+309479803094804830946405309464813094834930948458-0.252000.000040.00122excludedK562U2AF2
    SEWRNENSG00000165392.5chr8+309991963099929130998977309991163100014131000217-0.061000.001200.04330excludedK562TARDBP
    SEWRNENSG00000165392.5chr8+309166683091678130915887309160593092180430921950-0.102000.003680.09954excludedK562TARDBP
    SEWRNENSG00000165392.5chr8+3095799530958068309542833095436630958364309584710.102000.000010.00091includedK562SF3B1
    SEWRNENSG00000165392.5chr8+309336883093380330925773309258433093838230938812-0.080000.000270.01449excludedK562SF3B1
    SEWRNENSG00000165392.5chr8+3102359131023682310148833101504631024537310247460.066000.000010.00057includedK562PTBP1
    SEWRNENSG00000165392.5chr8+309479803094804830946405309464813094834930948458-0.334000.000020.00062excludedK562HNRNPC
    A3SSWRNENSG00000165392.5chr8+3094784430948048309479803094804830946405309464810.066000.002840.08632longerK562U2AF2
    A3SSWRNENSG00000165392.5chr8+309224303092257930922441309225793092180430921950-0.095000.000310.02092shorterK562SF3B4
    A3SSWRNENSG00000165392.5chr8+3092574130925843309257733092584330924548309246980.095000.000190.00158longerK562AQR
    A3SSWRNENSG00000165392.5chr8+3096911530969315309691303096931530958364309584710.112000.000000.00000longerK562AQR
    A3SSWRNENSG00000165392.5chr8+3094795830948048309479803094804830946239309464810.146000.000040.00035longerK562AQR
    A3SSWRNENSG00000165392.5chr8+3091661030916781309166683091678130915887309160590.210000.000010.00050longerK562PUS1
    A3SSWRNENSG00000165392.5chr8+3091661030916781309166683091678130915898309160590.208000.000000.00157longerK562UTP18
    MXEWRNENSG00000165392.5chr8+3092180430921950309224413092257930916668309167813092454830924698-0.169000.001920.051762includedK562RBM15

    *: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
    **: "-log(0)" was displayed as "99999.99999".





    No autoregularoty alternative splicing events between protein WRN and its RNA.