EXOSC5

General Information

Gene Name       : EXOSC5
Gene ID             : ENSG00000077348.8
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: EXOSC5)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878EXOSC5ENSG00000077348.81.6010.726.16ENCSR000AEF
HepG2EXOSC5ENSG00000077348.821.155.0813.11ENCSR985KAT
K562EXOSC5ENSG00000077348.834.1514.9724.56ENCSR000AEO

Assays

4 Released experiments are available on ENCORE database.

Assay TypeExp_NameENCODE IDTarget labelBiosampleStatusLinked AntibodyControlsMethodNote
eCLIPeCLIP: 491ENCSR013CTQEXOSC5K562ReleasedENCAB480FQKENCSR308RMD  
eCLIPeCLIP: 722ENCSR693JWPEXOSC5HepG2ReleasedENCAB480FQKENCSR831WYG  
knockdown followed by RNA-seq EXOSC5-BGKcLV06-K562ENCSR406SEHEXOSC5K562ReleasedENCSR341TTW   CRISPRKD% = 77.7,81.4
knockdown followed by RNA-seq EXOSC5-BGHcLV07-HepG2ENCSR284SZOEXOSC5HepG2ReleasedENCSR521WAI   CRISPRKD% = 56.9,60.5






  eCLIP  
  RBP    Exp_UID    Cell_Line    ENCODE_ACCESSION    Control_ENCODE_ACCESSION    ENCODE_Antibody_ID    Antibody    Lot_num    Status    Project  
EXOSC5491K562ENCSR013CTQENCSR308RMDENCAB480FQKRN100PW1ReleasedENCODE3
EXOSC5722HepG2ENCSR693JWPENCSR831WYGENCAB480FQKRN100PW1ReleasedENCODE4


  Antibody Validation  
  GeneName    Antibody_DCC_ID    Product_ID    Lot_ID    Phosphate    HepG2 Primary Validation    K562 Primary Validation    HepG2 Secondary Validation    K562 Secondary Validation  
EXOSC5ENCAB480FQKRN100PW1Released, ENCODE3Released, ENCODE3BGHcLV07-13, Released, ENCODE3BGKcLV06-13, Released, ENCODE3


  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
EXOSC5K562CRISPRENCSR406SEHENCSR341TTWEXOSC5-BGKcLV06-13,EXOSC5-BGKcLV06-14NT-BGKcLV06-1,NT-BGKcLV06-277.7,81.4ReleasedENCODE3
EXOSC5HepG2CRISPRENCSR284SZOENCSR521WAIEXOSC5-BGHcLV07-13,EXOSC5-BGHcLV07-14NT-BGHcLV07-1,NT-BGHcLV07-256.9,60.5ReleasedENCODE3


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela
EXOSC5Product_ID: RN100PW
Lot_ID: 1
Source: MBLI
Target Name: EXOSC5-human		 HepG2_MBLI_RN100PW_001_EXOSC5.png<br>Caption: IP-Western Blot analysis of HepG2 whole cell lysate using EXOSC5 specific antibody. Lane 1 is 1% of twenty million whole cell lysate input and lane 2 is 25% of IP enrichment using rabbit normal IgG (lanes under 'IgG'). Lane 3 is 1% of twenty million whole cell lysate input and lane 4 is 10% IP enrichment using rabbit polyclonal anti-EXOSC5 antibody (lanes under 'EXOSC5').
 EXOSC5-CRISPR-HEPG2.png<br>Caption: Western blot following CRISPR against EXOSC5 in HepG2 whole cell lysate using EXOSC5 specific antibody. Lane 1 is a ladder, lane 2 is HepG2 non-targeting control knockdown, lane 3 and 4 are two different CRISPR against EXOSC5. EXOSC5 protein appears as the green arrow, Tubulin serves as a control and appears in red arrow.
 K562_MBLI_RN100PW_001_EXOSC5.png<br>Caption: IP-Western Blot analysis of K562 whole cell lysate using EXOSC5 specific antibody. Lane 1 is 1% of twenty million whole cell lysate input and lane 2 is 25% of IP enrichment using rabbit normal IgG (lanes under 'IgG'). Lane 3 is 1% of twenty million whole cell lysate input and lane 4 is 10% IP enrichment using rabbit polyclonal anti-EXOSC5 antibody (lanes under 'EXOSC5').
 EXOSC5-CRISPR-K562.png<br>Caption: Western blot following CRISPR against EXOSC5 in K562 whole cell lysate using EXOSC5 specific antibody. Lane 1 is a ladder, lane 2 is K562 non-targeting control knockdown, lane 3 and 4 are two different CRISPR against EXOSC5. EXOSC5 protein appears as the green arrow, Tubulin serves as a control and appears in red arrow.








RNA Targets
  • EXOSC5 protein binds to 12,739 RNA regions.  





Proteins bound to RNA
  • EXOSC5 RNA is bound by 2 proteins.  






EXOSC5 protein has 12,739 RNA targets:

Only display 100 entries as example. Please click "View All" button to see all 12,739 entries.     

RBP Chr Start End Strand log2(fold change) -log(p-value) Cell Line Matched Gene Matched Area
EXOSC5chr7124544784124544822-4.1322010.62063K562POT1intron-Distal
EXOSC5chr16601954966019601+4.167983.89080K562LEPRintron-Distal
EXOSC5chr17761724477617276-4.064763.30687K562PIGKintron-Distal
EXOSC5chr3124495359124495374-6.5739525.38392K562ITGB5intron-Distal
EXOSC5chr8123844340123844423+4.746715.05990HepG2ZHX2intron-Distal
EXOSC5chr152522977925229845+4.605417.38704HepG2SNHG14, SNURFintron-Distal
EXOSC5chr7151748186151748238+4.097303.01445K562GALNT11intron-Distal
EXOSC5chr2201727554201727621-3.249734.46778K562CLK1intron-Distal
EXOSC5chr1207523758207523816+5.0929720.90108K562CD55intron-Distal
EXOSC5chr32831393428313973+5.5999511.99379K562CMC1intron-Distal
EXOSC5chr1100834333100834380+4.040306.71166K562CDC14Aintron-Distal
EXOSC5chr14481217144812217-3.583023.72952K562ERI3intron-Distal
EXOSC5chrX6774756167747612+4.664774.48560K562YIPF6intron-Distal
EXOSC5chr22780905227809143+4.592653.59762HepG2ZNF512, RP11-158I13.2intron-Distal
EXOSC5chr222266057022660650+4.022875.80937K562LL22NC03-80A10.6, BMS1P20intron-Distal
EXOSC5chr1813200501320092-3.334844.74410K562LINC00470intron-Distal
EXOSC5chr146849173268491803+6.2062216.32299K562RAD51Bintron-Distal
EXOSC5chr81167419111674223+4.299507.91405K562FDFT1intron-Distal
EXOSC5chr89075852490758590-4.053573.01445K562RP11-37B2.1intron-Distal
EXOSC5chr7158440818158440861-6.8143729.08826K562NCAPG2intron-Distal
EXOSC5chr192129527421295311+5.119078.69493K562ZNF714intron-Distal
EXOSC5chr168938118589381244-4.967916.41216K562ANKRD11intron-Distal
EXOSC5chr3135989837135989877+3.860935.20960K562PCCBintron-Distal
EXOSC5chr2177172695177172739+4.9841212.87128K562MTX2intron-Distal
EXOSC5chr12702858127028624+3.6295712.49695K562ARID1Aintron-Distal
EXOSC5chr2173439950173440062+3.680015.39126HepG2PDK1intron-Distal
EXOSC5chr2148721572148721619-5.7178737.68272K562ORC4intron-Distal
EXOSC5chr13114194487114194582+3.957253.01456K562TMCO3intron-Distal
EXOSC5chr5285739285771+4.746714.97153HepG2PDCD6intron-Distal
EXOSC5chr84837223548372315+5.203188.03988K562SPIDRintron-Distal
EXOSC5chr4169903324169903372-4.575775.12361K562CBR4intron-Distal
EXOSC5chr31588100515881100-5.3224837.50095K562ANKRD28intron-Distal
EXOSC5chr7112512345112512406-5.262508.03988K562C7orf60intron-Distal
EXOSC5chr9117052526117052597+3.035324.31558HepG2COL27A13'-UTR,CDS
EXOSC5chr34732447647324502+3.346053.72952K562KLHL185'-UTR,CDS
EXOSC5chr950198485019917+3.167985.13755K562JAK2intron-Distal
EXOSC5chr39366960093669754-5.272287.71312K562PROS1intron-Distal
EXOSC5chr221910480419104891-4.9361918.63259K562DGCR2intron-Distal
EXOSC5chr9140617004140617101+6.3962420.67406K562EHMT1intron-Distal
EXOSC5chr143111525531115292+3.647395.29801K562SCFD1intron-Distal
EXOSC5chr11483770483885+3.462077.41097K562PTDSS2intron-Distal
EXOSC5chr6111779871111779895-5.0243414.49454K562REV3Lintron-Distal
EXOSC5chr3124988177124988224-3.083023.64681K562ZNF148, SLC12A8intron-Distal
EXOSC5chr161050620610506255+4.1665611.23387K562ATF7IP2intron-Distal
EXOSC5chr648446164844656+4.7995011.25934K562CDYLintron-Distal
EXOSC5chr17807591978075955-5.4304610.67163K562ZZZ3intron-Distal
EXOSC5chr15123404351234075-5.9276713.32155K562FAF1intron-Distal
EXOSC5chrX1830156418301590-4.346054.48560K562SCML2intron-Distal
EXOSC5chr7156667329156667377-3.886245.20902K562LMBR1intron-Distal
EXOSC5chr157285095372851015+4.338503.89085K562ARIH1intron-Distal
EXOSC5chr99410657894106630-4.014993.30696K562AUHintron-Distal
EXOSC5chr4151797881151797941-4.214547.91454K562LRBAintron-Distal
EXOSC5chr2227707765227707817+4.815356.73731K562RHBDD1intron-Distal
EXOSC5chr79159743991597495+4.4209319.12416K562AKAP9intron-Distal
EXOSC5chr153008805430088136-5.4657910.34009K562TJP1intron-Distal
EXOSC5chr193488312034883138+6.59068400.00000K562GPIintron-Distal
EXOSC5chr32568945925689512-3.410703.43829K562TOP2Bintron-Distal
EXOSC5chr3130644364130644432+3.167983.43829K562ATP2C1intron-Distal
EXOSC5chr168948485189484909-4.844806.73731K562ANKRD11intron-Distal,intron-Proximal
EXOSC5chrX153917023153917082-6.4166821.00970K562GAB3intron-Distal
EXOSC5chr8124376983124377014-5.299509.02315K562ATAD2intron-Distal
EXOSC5chr9140616444140616483+4.7667112.22629K562EHMT1intron-Distal
EXOSC5chr3135991330135991363+4.249733.59909K562PCCBintron-Distal
EXOSC5chr193487870334878830+7.0465738.78546HepG2GPIintron-Distal
EXOSC5chr16601686766016931+4.7323514.58103K562LEPRintron-Distal
EXOSC5chr7102593601102593651-4.258273.89085K562FBXL13intron-Distal
EXOSC5chr132061461220614646+6.3862417.65810K562ZMYM2intron-Distal
EXOSC5chr166814308068143112+5.254017.71312K562RP11-67A1.2, NFATC3intron-Distal
EXOSC5chr7107149327107149423-3.397605.29801K562COG5intron-Distal
EXOSC5chr58755751387557548-4.111313.30687K562TMEM161Bintron-Distal
EXOSC5chr1225614548225614610-5.3331018.42282K562LBRintron-Distal
EXOSC5chr134972418649724246+4.425998.80887K562FNDC3Aintron-Distal
EXOSC5chr21548513215485188-5.258279.02435K562NBASintron-Distal
EXOSC5chr5104537331104537357-4.249733.59909K562CTD-2374C24.1, RP11-6N13.1intron-Distal
EXOSC5chr3171026146171026198-5.067538.04096K562TNIKintron-Distal
EXOSC5chr129677644696776505-4.2394811.23387K562CDK17intron-Distal
EXOSC5chr99410310794103168-4.007029.08614K562AUHintron-Distal
EXOSC5chr12112399049112399108-4.862155.44433K562TMEM116intron-Distal
EXOSC5chr1246447255246447291-3.389794.02190K562SMYD3intron-Distal
EXOSC5chr104330993643309981+3.743984.91037K562BMS1intron-Distal
EXOSC5chr1230216873230216937+3.309524.74379K562GALNT2intron-Distal
EXOSC5chr68941260589412648-4.431025.12361K562RNGTTintron-Distal
EXOSC5chr161229692212296994+4.262507.01277K562SNX29intron-Distal
EXOSC5chr12112398084112398135-4.191647.91454K562TMEM116intron-Distal
EXOSC5chr9134043304134043329+4.007029.08614K562NUP214intron-Distal
EXOSC5chr214426835944268434-4.4095518.20189K562WDR4intron-Distal
EXOSC5chr2227707296227707371+4.490814.48560K562RHBDD1intron-Distal
EXOSC5chr24242627542426309+3.396498.04192HepG2EML4intron-Distal
EXOSC5chr64522869145228751-4.305498.80887K562SUPT3Hintron-Distal
EXOSC5chr6168261499168261536+3.894495.50914K562MLLT4intron-Distal
EXOSC5chr5883111883155-4.1340710.92788K562BRD9intron-Distal
EXOSC5chr7155476248155476304+3.6930610.98514K562RBM33intron-Distal
EXOSC5chr2170473890170473908+5.115638.03988K562PPIGintron-Distal
EXOSC5chr72468599424686026+4.348554.80399K562MPP6intron-Distal
EXOSC5chr31588733915887378-5.249738.36716K562ANKRD28intron-Distal
EXOSC5chr19310561993105659-3.862154.61337K562EVI5intron-Distal
EXOSC5chr72350273923502814-3.626754.02241K562IGF2BP3intron-Distal
EXOSC5chr164758502547585072+3.957253.01456K562PHKBintron-Distal
EXOSC5chr1246074461246074493-4.749735.12432K562SMYD3intron-Distal
EXOSC5chr1985431188543168+5.1230331.84615K562HNRNPMintron-Distal




2 proteins are bound to EXOSC5 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr194189238141892517-3'-UTR,CDS,intron-Distal4.385587.37833K562PABPC4
chr194189243041892550-3'-UTR,CDS,intron-Distal3.345743.82830HepG2LARP4
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




No autoregularoty interactions between protein EXOSC5 and its RNA.



Diffrential Expression
  • 1,665 differentially expressed genes after Knockdown/Knockout EXOSC5 protein.  





  • 79 RBPs can affect the levels of EXOSC5.  







1,665 differentially expressed genes after Knockdown/Knockout EXOSC5 protein :

Only display 100 entries as example. Please click "View All" button to see all 1,665 entries.     

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
CYP51A1ENSG00000001630.112946.456203771.84030-0.356303.670001.35290HepG2EXOSC5
ANLNENSG00000011426.61193.713301585.88870-0.409803.656401.34500HepG2EXOSC5
RGPD5ENSG00000015568.8234.42900525.73560-1.1652013.8045010.40420HepG2EXOSC5
RTEL1-TNFRSF6BENSG00000026036.16205.8393096.751501.089106.454903.48060HepG2EXOSC5
TIMP2ENSG00000035862.8858.70140617.904000.474703.887501.50150HepG2EXOSC5
BCAT1ENSG00000060982.10438.82680625.10880-0.510503.923901.52370HepG2EXOSC5
TPX2ENSG00000088325.112361.475103090.42770-0.388103.961801.54680HepG2EXOSC5
KIF4AENSG00000090889.10344.20980508.06290-0.561704.011301.58110HepG2EXOSC5
ITPR3ENSG00000096433.6763.16620493.675900.628305.743402.88020HepG2EXOSC5
CATSPERGENSG00000099338.18190.2659016.096603.5631030.2237026.17020HepG2EXOSC5
STX1BENSG00000099365.5122.2986049.950001.291805.744002.88020HepG2EXOSC5
SBF1ENSG00000100241.16704.78990497.400700.502704.114601.66320HepG2EXOSC5
PNNENSG00000100941.49468.512707263.596800.382403.832001.46470HepG2EXOSC5
NDRG4ENSG00000103034.10110.7926042.000901.399305.612902.80720HepG2EXOSC5
RPL18AENSG00000105640.82590.819201962.347400.400704.271301.75800HepG2EXOSC5
C1QBPENSG00000108561.41466.818201900.61250-0.373803.588701.30610HepG2EXOSC5
HSPA8ENSG00000109971.913312.7261017351.61170-0.382304.488301.91910HepG2EXOSC5
SLC1A2ENSG00000110436.72743.615203593.96500-0.389504.193401.71970HepG2EXOSC5
KNG1ENSG00000113889.7648.75330935.67700-0.528304.654202.05560HepG2EXOSC5
HSPE1ENSG00000115541.62511.830203337.30750-0.409904.129001.67210HepG2EXOSC5
TCP1ENSG00000120438.72794.108903714.05970-0.410604.684702.07840HepG2EXOSC5
HSPH1ENSG00000120694.151021.037001373.07950-0.427403.845101.47030HepG2EXOSC5
TNFSF10ENSG00000121858.61238.130201631.38520-0.397903.654201.34500HepG2EXOSC5
KLHL31ENSG00000124743.569.6949017.523901.991606.284603.36150HepG2EXOSC5
TNFSF14ENSG00000125735.6245.82390137.496900.838104.937802.21670HepG2EXOSC5
ZFC3H1ENSG00000133858.111337.34040978.624300.450404.254101.75690HepG2EXOSC5
AGTENSG00000135744.737957.1665029528.818000.362103.702601.37340HepG2EXOSC5
ALPK3ENSG00000136383.648.7338010.460102.219905.232302.49060HepG2EXOSC5
C1RLENSG00000139178.61390.02290995.160000.482004.903102.19200HepG2EXOSC5
IFITM3ENSG00000142089.11878.76670604.799200.538904.887802.18650HepG2EXOSC5
OSMRENSG00000145623.82894.543302137.261200.437504.731802.10150HepG2EXOSC5
BHMTENSG00000145692.10292.41300496.14880-0.762806.563803.55170HepG2EXOSC5
TNFRSF21ENSG00000146072.61211.50520895.595700.435803.924801.52370HepG2EXOSC5
ANKRD1ENSG00000148677.6358.96620127.025301.4986015.7327012.15630HepG2EXOSC5
SERPING1ENSG00000149131.11936.16100670.033000.482404.265701.75800HepG2EXOSC5
PART1ENSG00000152931.7172.6614095.755500.850403.675301.35420HepG2EXOSC5
DBIENSG00000155368.124066.513405423.32190-0.415404.810802.13760HepG2EXOSC5
CCNB2ENSG00000157456.3323.54480474.87360-0.553603.897201.50210HepG2EXOSC5
RACGAP1ENSG00000161800.8446.48040642.56790-0.525303.854701.47330HepG2EXOSC5
TSSK3ENSG00000162526.640.9003010.841801.915403.683801.35870HepG2EXOSC5
PRORSD1PENSG00000162997.11112.3253053.888301.059503.932101.52370HepG2EXOSC5
HMGB2ENSG00000164104.71137.227201535.54930-0.433204.159201.69670HepG2EXOSC5
ANXA5ENSG00000164111.103407.828204362.14560-0.356203.792701.44270HepG2EXOSC5
NOS3ENSG00000164867.6105.9183049.175301.106803.985101.56000HepG2EXOSC5
INTS1ENSG00000164880.11670.99500470.389700.512304.012701.58110HepG2EXOSC5
TERF2IPENSG00000166848.5935.657601246.06940-0.413303.632801.33520HepG2EXOSC5
MAT2AENSG00000168906.84101.112101962.018701.0636025.4280021.67560HepG2EXOSC5
ARL6IP1ENSG00000170540.103100.041804245.35140-0.453604.719402.09730HepG2EXOSC5
LRG1ENSG00000171236.9638.47140390.940700.707606.398203.44170HepG2EXOSC5
RRM2ENSG00000171848.91526.796802042.24600-0.419604.294401.77240HepG2EXOSC5
PCENSG00000173599.9815.09400577.574700.496904.034501.59380HepG2EXOSC5
STAG3L3ENSG00000174353.13259.35120141.755700.871405.265402.51290HepG2EXOSC5
PDZK1ENSG00000174827.91061.085501408.43640-0.408603.754401.41690HepG2EXOSC5
COL18A1ENSG00000182871.101824.335501331.178300.454603.842601.47030HepG2EXOSC5
RGPD6ENSG00000183054.7814.03740556.891000.547604.782002.11770HepG2EXOSC5
CSF1ENSG00000184371.9508.74150318.753900.674405.605402.80720HepG2EXOSC5
DNAH17ENSG00000187775.12280.71950150.677900.897605.823002.93090HepG2EXOSC5
PLA2G2AENSG00000188257.669.1915026.175201.402303.973501.55340HepG2EXOSC5
COLCA1ENSG00000196167.5143.2572067.893601.077204.687702.07840HepG2EXOSC5
TGM2ENSG00000198959.7571.99210356.732400.681105.687002.85260HepG2EXOSC5
AC084018.1ENSG00000212694.4597.14400312.243500.9353010.400707.12540HepG2EXOSC5
KRTAP3-1ENSG00000212901.231.847605.365502.569304.217401.73210HepG2EXOSC5
C1orf220ENSG00000213057.488.6198037.780101.229903.892801.50210HepG2EXOSC5
SLX1A-SULT1A3ENSG00000213599.5175.0061069.763501.326807.755104.67930HepG2EXOSC5
TIGD1ENSG00000221944.3184.7721099.445800.893704.466901.90480HepG2EXOSC5
RP11-330M19.1ENSG00000225028.125.230700.492305.679406.360403.42090HepG2EXOSC5
FAM195BENSG00000225663.3256.38950152.521200.749204.197201.71970HepG2EXOSC5
LINC00115ENSG00000225880.469.0828027.602401.323403.623001.33290HepG2EXOSC5
MIR29B1ENSG00000226380.3106.7303014.398402.8899014.2598010.80840HepG2EXOSC5
MIR194-2ENSG00000229719.226.146403.778002.790803.788601.44270HepG2EXOSC5
RP11-1212A22.4ENSG00000233024.31080.823202030.80540-0.909909.775906.53540HepG2EXOSC5
RP11-57H14.2ENSG00000233547.131.845105.094602.643904.451701.89660HepG2EXOSC5
AC074117.10ENSG00000234072.1569.07270400.011700.508503.730201.39680HepG2EXOSC5
LINC00894ENSG00000235703.1101.8435048.683001.064803.589501.30610HepG2EXOSC5
SNHG3ENSG00000242125.21517.20830701.356101.1131021.1005017.44500HepG2EXOSC5
RNF139-AS1ENSG00000245149.3125.8600040.081301.650708.024604.90060HepG2EXOSC5
NEAT1ENSG00000245532.412047.532205907.907501.0279027.5693023.69190HepG2EXOSC5
CTD-3203P2.2ENSG00000245888.249.0449014.780001.730403.763101.42150HepG2EXOSC5
SNHG10ENSG00000247092.293.8076039.047101.264404.375401.84110HepG2EXOSC5
RP11-486O12.2ENSG00000247373.257.9939013.253602.129405.856902.94960HepG2EXOSC5
RP11-501C14.5ENSG00000250838.116.481500.0000099999.999904.743502.10160HepG2EXOSC5
ZNF252P-AS1ENSG00000255559.141.006508.380302.290704.829302.14690HepG2EXOSC5
HPENSG00000257017.43605.867902092.604700.784904.221301.73210HepG2EXOSC5
RN7SL1ENSG00000258486.2251.82620137.214500.875905.278602.51520HepG2EXOSC5
TUBB3ENSG00000258947.2675.69430455.880600.567604.878002.18630HepG2EXOSC5
RP11-480A16.1ENSG00000260261.1150.9896061.173301.303406.790603.75830HepG2EXOSC5
RP11-600F24.7ENSG00000260285.172.0346024.919701.531304.624902.04130HepG2EXOSC5
CTD-2526A2.2ENSG00000260369.217.602000.0000099999.999905.116802.38550HepG2EXOSC5
RP11-390B4.5ENSG00000260589.174.781509.967902.9072010.647607.33450HepG2EXOSC5
CAPN10-AS1ENSG00000260942.1181.1021061.482401.558509.659906.45150HepG2EXOSC5
RP11-355O1.11ENSG00000261094.2144.1728062.035801.216505.675702.85260HepG2EXOSC5
RP11-37C7.3ENSG00000261136.158.3000013.413902.119705.706402.85710HepG2EXOSC5
RP11-196G18.22ENSG00000261716.1171.4372081.883801.065904.538501.96210HepG2EXOSC5
RP11-102M11.2ENSG00000261758.134.387105.365502.680004.637802.04670HepG2EXOSC5
DLGAP1-AS2ENSG00000262001.1183.9526098.289500.904104.392601.85100HepG2EXOSC5
RP11-705O1.8ENSG00000263884.143.245003.667303.559607.811404.71220HepG2EXOSC5
RP11-173M1.5ENSG00000265683.119.228501.095204.133804.099401.65340HepG2EXOSC5
RP11-159D12.5ENSG00000266086.175.08510184.00080-1.293107.651004.59750HepG2EXOSC5
MIR4453ENSG00000268471.3161.6662057.383901.494208.395905.21750HepG2EXOSC5
RP11-18I14.10ENSG00000269609.1331.68940215.186600.624103.644001.33870HepG2EXOSC5
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





79 RBPs can affect the gene expression of EXOSC5 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
EXOSC5ENSG00000077348.4235.37860161.887800.539902.820002.04680HepG2AKAP8L
EXOSC5ENSG00000077348.4224.06430122.670300.869004.615403.86610HepG2BOP1
EXOSC5ENSG00000077348.4138.3357078.597600.815503.359902.23900HepG2YBX3
EXOSC5ENSG00000077348.455.20420116.27630-1.074702.942301.52800HepG2CSTF2T
EXOSC5ENSG00000077348.4204.07440149.336100.450401.897601.34640HepG2CELF1
EXOSC5ENSG00000077348.4111.04290160.56780-0.532102.099901.44140HepG2DAZAP1
EXOSC5ENSG00000077348.455.88390124.96880-1.161104.730403.86990HepG2DDX21
EXOSC5ENSG00000077348.456.30720122.47730-1.121104.250703.10800HepG2DDX24
EXOSC5ENSG00000077348.485.49960154.16320-0.850503.749102.98360HepG2DKC1
EXOSC5ENSG00000077348.4144.3252077.183000.902902.574101.89180HepG2DNAJC21
EXOSC5ENSG00000077348.4129.5755076.492600.760303.189302.49750HepG2DNAJC2
EXOSC5ENSG00000077348.4118.79860236.45560-0.993103.302002.65800HepG2EIF2S1
EXOSC5ENSG00000077348.4105.94720158.41450-0.580402.158601.40400HepG2EIF4G1
EXOSC5ENSG00000077348.4223.65160331.78970-0.569003.790203.10530HepG2ETF1
EXOSC5ENSG00000077348.4250.95260157.452900.672403.665002.70450HepG2EWSR1
EXOSC5ENSG00000077348.4211.91370118.580400.837503.192101.99060HepG2GRSF1
EXOSC5ENSG00000077348.4198.55290108.500100.871703.589202.01350HepG2HNRNPA0
EXOSC5ENSG00000077348.440.0552077.92240-0.960002.170501.59250HepG2HNRNPA1
EXOSC5ENSG00000077348.4291.04870146.263400.992609.135907.97880HepG2HNRNPL
EXOSC5ENSG00000077348.456.30820148.20100-1.396107.410905.96770HepG2HNRNPM
EXOSC5ENSG00000077348.4132.3846086.098500.620602.298601.74110HepG2HNRNPU
EXOSC5ENSG00000077348.4129.01080248.58600-0.946303.193902.47440HepG2IGF2BP2
EXOSC5ENSG00000077348.4129.9592087.947200.563202.029701.39030HepG2ILF2
EXOSC5ENSG00000077348.4462.09510265.330600.800303.731403.00850HepG2MATR3
EXOSC5ENSG00000077348.4105.89980173.83670-0.715002.873302.04950HepG2MSI2
EXOSC5ENSG00000077348.462.65240124.26010-0.987902.625301.68430HepG2MTPAP
EXOSC5ENSG00000077348.4311.12150159.219000.966406.578305.40740HepG2NOL12
EXOSC5ENSG00000077348.4124.70760241.70400-0.954702.976602.23000HepG2PABPC4
EXOSC5ENSG00000077348.4150.8863076.793500.974304.956003.99870HepG2PPIL4
EXOSC5ENSG00000077348.4161.39330253.89940-0.653702.868002.31270HepG2PTBP1
EXOSC5ENSG00000077348.4222.59020151.989900.550302.400401.83950HepG2PUF60
EXOSC5ENSG00000077348.4309.52100161.345700.939809.087208.14380HepG2PUM1
EXOSC5ENSG00000077348.4275.14190161.226800.771004.904704.02550HepG2PUM2
EXOSC5ENSG00000077348.4107.00360164.12830-0.617202.699902.08910HepG2PUS1
EXOSC5ENSG00000077348.490.79390249.52390-1.458507.883806.79700HepG2RBM25
EXOSC5ENSG00000077348.4183.21550282.53810-0.624902.743602.20390HepG2NELFE
EXOSC5ENSG00000077348.4188.4625076.676201.297309.319308.24620HepG2SAFB2
EXOSC5ENSG00000077348.469.35530120.56740-0.797802.436801.77300HepG2SF3B1
EXOSC5ENSG00000077348.4106.71380264.28250-1.308307.679706.77260HepG2SF3B4
EXOSC5ENSG00000077348.4134.4935089.420400.588802.110401.53760HepG2SMN1
EXOSC5ENSG00000077348.4226.94670134.154600.758402.772001.99030HepG2SNRNP70
EXOSC5ENSG00000077348.4195.02500313.21350-0.683504.916904.30300HepG2SRFBP1
EXOSC5ENSG00000077348.4159.38860275.87800-0.791503.818403.28530HepG2SRSF1
EXOSC5ENSG00000077348.4214.40290150.069900.514602.403601.81560HepG2SRSF5
EXOSC5ENSG00000077348.4100.92830271.93990-1.4300014.5331013.54500HepG2SSB
EXOSC5ENSG00000077348.4227.15280147.092200.626802.758301.47790HepG2SSRP1
EXOSC5ENSG00000077348.4263.36290170.669100.625802.353701.77140HepG2SUCLG1
EXOSC5ENSG00000077348.478.46840141.30430-0.848603.153902.43680HepG2SUPV3L1
EXOSC5ENSG00000077348.4166.1454084.407900.976905.452404.71210HepG2TRIM56
EXOSC5ENSG00000077348.4212.20570148.490400.515002.092301.34180HepG2TUFM
EXOSC5ENSG00000077348.4123.56970183.75020-0.572401.910301.37800HepG2U2AF1
EXOSC5ENSG00000077348.4173.9689083.457801.059605.028203.99870HepG2UCHL5
EXOSC5ENSG00000077348.4198.17980123.698400.679903.392102.74060HepG2UTP3
EXOSC5ENSG00000077348.454.27780140.91180-1.376407.957007.15370HepG2ZNF622
EXOSC5ENSG00000077348.4210.70030299.48060-0.507302.490101.37620K562AARS
EXOSC5ENSG00000077348.4611.41650430.447500.506203.607002.18920K562ABCF1
EXOSC5ENSG00000077348.4529.36390417.519300.342302.302901.77720K562AGGF1
EXOSC5ENSG00000077348.4363.86560550.81660-0.598203.885103.21320K562AQR
EXOSC5ENSG00000077348.4384.30150258.881300.569803.433602.23610K562CSTF2
EXOSC5ENSG00000077348.4509.57760391.078600.381702.583901.41550K562DDX21
EXOSC5ENSG00000077348.4409.21990299.105200.452103.064201.66540K562DDX27
EXOSC5ENSG00000077348.4668.69380423.056300.660408.354107.30250K562DDX47
EXOSC5ENSG00000077348.4354.44920228.933300.630602.841401.54360K562EEF2
EXOSC5ENSG00000077348.4224.20650109.171801.038106.455605.25450K562EIF3G
EXOSC5ENSG00000077348.4420.80600309.490100.443202.562801.74760K562FIP1L1
EXOSC5ENSG00000077348.4148.75940284.66510-0.936302.893001.73710K562FKBP4
EXOSC5ENSG00000077348.47.1906052.94320-2.880307.590006.29780K562G3BP2
EXOSC5ENSG00000077348.4902.39520667.738500.434402.594701.86090K562GRSF1
EXOSC5ENSG00000077348.4128.30430327.44270-1.351709.513708.45970K562HNRNPC
EXOSC5ENSG00000077348.4532.63760382.320400.478303.229502.07830K562HNRNPL
EXOSC5ENSG00000077348.4553.64230419.549500.400002.262101.53860K562HSPD1
EXOSC5ENSG00000077348.4185.61420352.86640-0.926804.508502.66220K562ILF2
EXOSC5ENSG00000077348.4210.46520317.41300-0.592803.280701.73790K562LARP7
EXOSC5ENSG00000077348.4338.86730218.132200.635403.223501.79930K562NONO
EXOSC5ENSG00000077348.4636.07900351.387300.856009.262807.52700K562PPIG
EXOSC5ENSG00000077348.4411.08330293.617300.485402.650501.76910K562PSIP1
EXOSC5ENSG00000077348.4624.39050430.858300.535102.429501.91330K562PUS1
EXOSC5ENSG00000077348.4364.80070268.034800.444602.393201.47660K562RCC2
EXOSC5ENSG00000077348.4457.27020219.127201.061208.303106.87560K562RPS19
EXOSC5ENSG00000077348.4332.94350455.12770-0.451003.301402.41400K562SF3A3
EXOSC5ENSG00000077348.4329.85440214.979700.617503.024801.31410K562SRP68
EXOSC5ENSG00000077348.4340.83000194.332600.810402.141301.42910K562TIA1
EXOSC5ENSG00000077348.4444.59650300.170000.566603.623202.51380K562TRIM56
EXOSC5ENSG00000077348.418.2296051.26400-1.491703.253702.04700K562U2AF1
EXOSC5ENSG00000077348.413.2921052.96260-1.994405.360804.24790K562U2AF2
EXOSC5ENSG00000077348.4361.03900224.576000.684903.539002.11020K562XRN2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





77 alternative splicing events after Knockdown/Knockout EXOSC5 protein :

Only display 100 entries as example. Please click "View All" button to see all 77 entries.     

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SESNRNP70ENSG00000104852.10chr19+4960537049606844496046464960472849607890496079920.066000.000000.00009includedK562EXOSC5
SEPIGXENSG00000163964.9chr3+1964535251964536421964492851964494271964547931964549080.163000.000080.07326includedK562EXOSC5
SESTK19ENSG00000204344.10chr6+3194039731940534319400783194028831946679319467750.188000.000110.08999includedK562EXOSC5
SEZNF207ENSG00000010244.12chr17+3069368330693776306923483069250630694790306949620.119000.000010.02240includedK562EXOSC5
SEATP5SLENSG00000105341.14chr19-4193917641939339419372434193831341939441419395780.220000.000050.05236includedK562EXOSC5
SEIGBP1ENSG00000089289.11chrX+6938219569382314693700596937017269385682693861740.073000.000000.00040includedK562EXOSC5
SEPPP2R2DENSG00000175470.14chr10+1337483971337485101337479591337480591337535341337537000.199000.000010.02225includedK562EXOSC5
SECREBZFENSG00000137504.9chr11-8537422285374337853729968537350185374567853746450.156000.000070.06663includedK562EXOSC5
SETRNAU1APENSG00000180098.5chr1+2888762428887772288871442888724428887857288879100.089000.000000.00516includedK562EXOSC5
SEIP6K2ENSG00000068745.10chr3-4875282148752960487314834873285148754589487546470.172000.000010.01191includedK562EXOSC5
SEMCM3ENSG00000112118.13chr6-5213002252130183521288065212958452130872521309420.162000.000040.04164includedK562EXOSC5
SERPL17ENSG00000265681.2chr18-4701818947018203470178864701795447018644470187690.298000.000000.00000includedK562EXOSC5
SESAP30BPENSG00000161526.10chr17+7368675073686852736678957366794373689519736895620.151000.000100.08915includedK562EXOSC5
SESRSF3ENSG00000112081.12chr6+3656759736568053365665843656676036568928365689670.068000.000010.01149includedK562EXOSC5
SEC7orf55-LUC7L2ENSG00000146963.13chr7+1390479211390480051390446531390450681390608071390609020.106000.000090.07686includedK562EXOSC5
SEAC079466.1ENSG00000266976.1chr19+291028922910306129097594290980112910334529106136-0.124000.000030.04132excludedK562EXOSC5
SENUB1ENSG00000013374.11chr7+151071182151071287151065820151065973151072933151073029-0.125000.000030.03464excludedK562EXOSC5
SEERP29ENSG00000089248.6chr12+112457559112457698112451119112451413112459953112460972-0.107000.000000.00939excludedK562EXOSC5
SEFANCD2ENSG00000144554.6chr3+101145541011466510108892101090011011493610115046-0.061000.000030.03701excludedK562EXOSC5
SEQSOX2ENSG00000165661.11chr9-139116706139116755139115852139115958139118619139118720-0.133000.000080.07326excludedK562EXOSC5
SEUBA2ENSG00000126261.8chr19+349214803492156434919388349194753492276534922938-0.111000.000000.00636excludedK562EXOSC5
SEYIF1BENSG00000167645.12chr19-388060643880617038800056388002833880650838806582-0.174000.000000.00346excludedK562EXOSC5
SEPIN1ENSG00000127445.9chr19+994749899475519946044994607899491119949324-0.081000.000000.00037excludedK562EXOSC5
SEEIF4A2ENSG00000156976.10chr3+186506098186506209186505542186505671186506913186507080-0.056000.000020.02460excludedK562EXOSC5
SESTAMENSG00000136738.10chr10+177421671774227817738773177388681774642917746517-0.083000.000100.08915excludedK562EXOSC5
SEGYPAENSG00000170180.15chr4-145039866145039905145038006145038092145040838145040934-0.076000.000050.05500excludedK562EXOSC5
SEHMGCS1ENSG00000112972.10chr5-432981104329823643297103432972684329861943299077-0.061000.000110.09221excludedK562EXOSC5
SERPL5ENSG00000122406.8chr1+932989589329901593297581932976749329910193299217-0.052000.000000.00000excludedK562EXOSC5
SECALUENSG00000128595.12chr7+128388626128388858128379416128379486128398924128399091-0.171000.000020.03240excludedK562EXOSC5
SERNF181ENSG00000168894.5chr2+858239448582405485823641858237728582422685824704-0.083000.000050.05616excludedK562EXOSC5
SEPACSIN2ENSG00000100266.13chr22-432728934327301643272142432723394327505343275175-0.153000.000040.04450excludedK562EXOSC5
A5SSHDAC5ENSG00000108840.11chr17-4216974842169895421697634216989542169539421696520.147000.000050.08793longerK562EXOSC5
A5SSTXNRD1ENSG00000198431.11chr12+1046808261046809961046808261046808871046827081046828180.061000.000070.09844longerK562EXOSC5
A5SSTMEM165ENSG00000134851.8chr4+5628409956284331562840995628415256290704562908100.092000.000030.07315longerK562EXOSC5
A5SSOCIAD1ENSG00000109180.10chr4+4883463648834778488346364883469948835417488354980.092000.000100.09844longerK562EXOSC5
A5SSRPL17ENSG00000265681.2chr18-470181054701820347018189470182034701788647017954-0.137000.000000.00000shorterK562EXOSC5
A5SSDAP3ENSG00000132676.11chr1+155658881155659034155658881155658965155679563155679615-0.070000.000080.09844shorterK562EXOSC5
MXEAPEHENSG00000164062.8chr3+49711921497120544971261549712742497117994971184649713126497132200.218000.000010.004191includedK562EXOSC5
MXESNRNP70ENSG00000104852.10chr19+49589661495898184959354749593610495886794958889349593722495937770.153000.000000.000391includedK562EXOSC5
MXETXNRD1ENSG00000198431.11chr12+1046827081046828181047050671047051901046807261046811241047070221047070950.180000.000120.030861includedK562EXOSC5
MXEABHD14A-ACY1ENSG00000114786.11chr3+52019376520194815201986752019962520180625201817452020270520203470.161000.000550.090651includedK562EXOSC5
MXECIZ1ENSG00000148337.15chr9-1309429991309430781309478251309480551309426931309428021309501411309502130.094000.000630.097211includedK562EXOSC5
MXEACAT1ENSG00000075239.9chr11+1080026331080026811080045461080046641079922931079924051080049471080050430.104000.000570.091971includedK562EXOSC5
MXECDKN3ENSG00000100526.15chr14+54878250548784245488261654882648548754625487550754884565548846690.073000.000510.086981includedK562EXOSC5
MXEEP300ENSG00000100393.9chr22+41537051415372264154274241542820415361434153626141543840415439500.174000.000480.085711includedK562EXOSC5
MXESMAD5ENSG00000113658.12chr5+1354892801354898521354965441354967961354685351354686511354989601354990800.132000.000000.002311includedK562EXOSC5
MXERPL8ENSG00000161016.11chr8-1460166611460166951460171571460172991460157391460158551460173761460175250.114000.000010.004191includedK562EXOSC5
MXETALDO1ENSG00000177156.6chr11+7558787560027590087590577474537475787601217602530.056000.000110.030591includedK562EXOSC5
MXETALDO1ENSG00000177156.6chr11+7558787560027589497590577473287475787601217602530.065000.000020.006701includedK562EXOSC5
MXEATP5BENSG00000110955.4chr12-57037620570377425703895457039137570371865703737157039620570397510.081000.000420.082021includedK562EXOSC5
MXERPL13AENSG00000142541.12chr19+49993106499931794999348849993554499908904999090149993731499938570.191000.000000.000001includedK562EXOSC5
MXERPL13AENSG00000142541.12chr19+49994035499941214999429649994356499937314999383349994681499948040.178000.000000.000001includedK562EXOSC5
MXERPL13AENSG00000142541.12chr19+49994035499941214999432949994356499937364999383349994681499948040.161000.000000.000001includedK562EXOSC5
MXEGSDMBENSG00000073605.14chr17-38063213380632403806609238066177380623633806252438068578380687500.400000.000390.078241includedK562EXOSC5
MXEGSDMBENSG00000073605.14chr17-38063213380632403806600838066177380623633806252438068578380687500.396000.000280.062011includedK562EXOSC5
MXEGSDMBENSG00000073605.14chr17-38063213380632403806442838064467380623633806252438065210380652950.508000.000340.071721includedK562EXOSC5
MXECYB5R1ENSG00000159348.8chr1-2029350142029351212029358762029360262029344982029346282029363182029364080.217000.000070.021721includedK562EXOSC5
MXERPL5ENSG00000122406.8chr1+93299101932992179330033593300470932976209329767493301746933019110.066000.000000.000001includedK562EXOSC5
MXECCT6AENSG00000146731.6chr7+56120114561201785612206156122196561193225611967856123316561234900.059000.000130.033931includedK562EXOSC5
MXEWACENSG00000095787.17chr10+2889711428897360288996272889975028879648288797612890070228900851-0.061000.000320.067912includedK562EXOSC5
MXETMEM165ENSG00000134851.8chr4+5628409956284152562842145628433156283969562840155629070456290810-0.099000.000440.082552includedK562EXOSC5
MXEEGFL7ENSG00000172889.11chr9+139565401139565466139566377139566540139564620139564782139566715139567130-0.116000.000000.002312includedK562EXOSC5
MXETCF3ENSG00000071564.10chr19-16122051612432161528316155191611702161184816156841615820-0.127000.000220.050662includedK562EXOSC5
MXEOGDHENSG00000105953.10chr7+4468704244687133446872554468735844684925446851174470633444706450-0.118000.000110.030592includedK562EXOSC5
MXEALAS2ENSG00000158578.14chrX-5504117955041448550420105504217555039918550400815504391855044098-0.066000.000500.086462includedK562EXOSC5
MXEEI24ENSG00000149547.10chr11+125449988125450100125451106125451218125448844125448964125452241125452315-0.117000.000160.038352includedK562EXOSC5
MXEMED15ENSG00000099917.13chr22+2092939920929519209368972093703420922807209229182093712620937254-0.106000.000030.011812includedK562EXOSC5
MXEMED15ENSG00000099917.13chr22+2092939920929519209369452093703420922807209229182093712620937254-0.118000.000090.025382includedK562EXOSC5
MXEMED15ENSG00000099917.13chr22+2092939920929519209369482093703420922807209229182093712620937254-0.119000.000080.025382includedK562EXOSC5
MXETSSC2ENSG00000223756.2chr11+34061283406198341834634186363405396340551434229883423097-0.187000.000430.082022includedK562EXOSC5
MXERPL13AENSG00000142541.12chr19+4999348849993554499937314999383349993106499931794999403549994485-0.125000.000000.000012includedK562EXOSC5
MXESRMENSG00000116649.5chr1-1111501811115141111158371111598311114645111149421111606711116151-0.094000.000040.014102includedK562EXOSC5
MXEEEF1DENSG00000104529.13chr8-144663223144663324144668898144669019144662675144662897144679517144679914-0.098000.000020.008532includedK562EXOSC5
MXEEEF1DENSG00000104529.13chr8-144663223144663324144668898144669022144662675144662897144679517144679595-0.142000.000000.000392includedK562EXOSC5
MXEEEF1DENSG00000104529.13chr8-144663223144663498144668898144669022144662733144662897144679517144679570-0.141000.000000.000392includedK562EXOSC5
MXEEEF1DENSG00000104529.13chr8-144663398144663498144668898144669022144663223144663324144679517144679595-0.121000.000000.000062includedK562EXOSC5
MXEEEF1DENSG00000104529.13chr8-144663398144663498144668898144669019144663223144663324144679517144679914-0.167000.000000.000632includedK562EXOSC5






No RBPs affect the alternative splcing events of EXOSC5 on ENCORE database.





No autoregularoty alternative splicing events between protein EXOSC5 and its RNA.