GAB3

General Information

Gene Name       : GAB3
Gene ID             : ENSG00000160219.11
Essential Gene : No

Functions

Localization

Domains (AlphaFold: GAB3)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878GAB3ENSG00000160219.110.640.630.64ENCSR000AEF
HepG2GAB3ENSG00000160219.110.000.000.00ENCSR985KAT
K562GAB3ENSG00000160219.1118.9221.1420.03ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for GAB3 is not avaliable on ENCORE database.



Proteins bound to RNA
  • GAB3 RNA is bound by 26 proteins.  







eCLIP assay for GAB3 is not avaliable on ENCORE database.





26 proteins are bound to GAB3 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chrX153904754153904807-3'-UTR,intron-Distal3.996753.98636K562LIN28B
chrX153904706153904822-3'-UTR,intron-Distal3.029444.02491K562SAFB
chrX153904025153904098-3'-UTR,intron-Distal3.722697.50442K562UPF1
chrX153904315153904390-3'-UTR,intron-Distal,intron-Proximal4.103115.81489K562UPF1
chrX153904002153904074-3'-UTR,intron-Distal4.019434.84268K562SF3B4
chrX153906339153906380-3'-UTR,intron-Distal3.286067.70474K562DDX55
chrX153944544153944608-CDS,intron-Distal,intron-Proximal4.557885.85529K562RBM15
chrX153925475153925520-CDS,intron-Distal,intron-Proximal3.926426.80869K562AQR
chrX153927588153927627-CDS,intron-Distal3.018394.00731K562UCHL5
chrX153928303153928395-CDS,intron-Distal,intron-Proximal4.5447412.14994K562SF3B4
chrX153925483153925541-CDS,intron-Distal,intron-Proximal4.227754.42765K562SF3B4
chrX153941687153941750-CDS,intron-Distal,intron-Proximal4.680394.40745K562SF3B4
chrX153944568153944624-CDS,intron-Distal,intron-Proximal3.216235.12722K562BUD13
chrX153928308153928400-CDS,intron-Distal,intron-Proximal3.474293.99122K562SMNDC1
chrX153908509153908581-CDS,intron-Distal,intron-Proximal3.654166.26686K562SF3B4
chrX153940798153940884-CDS,intron-Distal3.289894.06924K562IGF2BP2
chrX153941565153941617-CDS,intron-Distal3.086343.34231K562RBM15
chrX153906547153906571-CDS,intron-Distal,intron-Proximal3.018394.00731K562UCHL5
chrX153940842153940905-CDS,intron-Distal4.555644.15208K562RBM15
chrX153917023153917082-intron-Distal6.4166821.00970K562EXOSC5
chrX153914136153914222-intron-Distal4.6731710.29675K562EXOSC5
chrX153979142153979218-intron-Distal3.612533.31456K562TIA1
chrX153933590153933612-intron-Distal3.389797.69952K562EXOSC5
chrX153930750153930785-intron-Distal4.4867013.37617K562EXOSC5
chrX153951932153952039-intron-Distal3.295626.32068K562MATR3
chrX153947578153947646-intron-Distal4.253284.18579K562MATR3
chrX153979423153979490-intron-Distal,intron-Proximal5.210465.59726K562GEMIN5
chrX153928971153929035-intron-Distal3.108573.23702K562PTBP1
chrX153969227153969297-intron-Distal3.815796.58753K562ILF3
chrX153961531153961658-intron-Distal3.255485.85987K562HNRNPL
chrX153979632153979727-intron-Distal4.390584.75311K562CSTF2T
chrX153930236153930269-intron-Distal4.607845.12361K562EXOSC5
chrX153933361153933433-intron-Distal3.521594.62044K562HNRNPM
chrX153978917153978965-intron-Distal3.746774.25264K562NONO
chrX153927479153927493-intron-Distal,intron-Proximal4.388893.62536K562AQR
chrX153928515153928563-intron-Distal3.309076.85960K562KHSRP
chrX153951604153951688-intron-Distal4.878486.77551K562MATR3
chrX153970115153970200-intron-Distal4.683066.21255K562ILF3
chrX153914278153914333-intron-Distal3.834846.96489K562EXOSC5
chrX153927387153927443-intron-Distal3.331156.02419K562AQR
chrX153947249153947344-intron-Distal4.342904.33150K562HNRNPK
chrX153933707153933743-intron-Distal4.476323.89080K562EXOSC5
chrX153913091153913194-intron-Distal3.626483.14313K562SAFB
chrX153978808153978879-intron-Distal3.336417.47864K562NONO
chrX153928966153929077-intron-Distal5.3654910.58856K562MATR3
chrX153939578153939633-intron-Distal4.986847.06647K562MATR3
chrX153939464153939535-intron-Distal4.739006.48506K562MATR3
chrX153951701153951775-intron-Distal3.383758.15991K562MATR3
chrX153929784153929884-intron-Distal3.031603.27187K562HNRNPM
chrX153930785153930823-intron-Distal4.2896412.46063K562EXOSC5
chrX153939633153939690-intron-Distal4.654035.04209K562MATR3
chrX153929077153929151-intron-Distal4.754855.90588K562MATR3
chrX153939870153939940-intron-Distal3.601685.33544K562MATR3
chrX153916930153916975-intron-Distal4.653416.08869K562EXOSC5
chrX153928370153928497-intron-Distal,intron-Proximal3.477589.48651K562KHSRP
chrX153957738153957837-intron-Distal3.309203.18966K562MATR3
chrX153954191153954281-intron-Distal4.586005.26569K562MATR3
chrX153978718153978808-intron-Distal4.145966.54942K562NONO
chrX153978575153978625-intron-Distal4.449955.59615K562NONO
chrX153971960153972084-intron-Distal5.457736.90462K562PTBP1
chrX153978638153978681-intron-Distal3.225933.77567K562NONO
chrX153919740153919843-intron-Distal3.666843.26999K562KHSRP
chrX153933386153933439-intron-Distal3.638544.31658K562EXOSC5
chrX153939440153939513-intron-Distal4.915289.53330K562PTBP1
chrX153939730153939828-intron-Distal4.5394510.39734K562MATR3
chrX153970065153970115-intron-Distal3.823833.08243K562ILF3
chrX153969892153969955-intron-Distal3.923793.62499K562HNRNPC
chrX153973924153974006-intron-Distal4.291544.24113K562MATR3
chrX153931403153931426-intron-Distal4.064763.30687K562EXOSC5
chrX153931121153931194-intron-Distal5.2493718.42282K562EXOSC5
chrX153971604153971711-intron-Distal3.715838.11042K562MATR3
chrX153916853153916930-intron-Distal3.729086.96489K562EXOSC5
chrX153933908153933964-intron-Distal3.726065.88553K562MATR3
chrX153935242153935335-intron-Distal3.238205.83938K562KHSRP
chrX153929829153929899-intron-Distal3.622339.95742K562EXOSC5
chrX153930581153930624-intron-Distal4.970025.44433K562EXOSC5
chrX153927501153927569-intron-Distal,intron-Proximal7.0795726.83343K562AQR
chrX153936592153936640-intron-Distal3.646844.61337K562EXOSC5
chrX153930114153930148-intron-Distal4.015987.01277K562EXOSC5
chrX153927338153927437-intron-Distal3.204874.47261K562EFTUD2
chrX153939568153939620-intron-Distal4.600608.54663K562PTBP1
chrX153939099153939221-intron-Distal3.311493.90716K562KHDRBS1
chrX153928760153928966-intron-Distal5.3941720.66501K562MATR3
chrX153931757153931814-intron-Distal3.315355.02053K562EXOSC5
chrX153972913153972980-intron-Distal3.6015511.99390K562KHSRP
chrX153912749153912835-intron-Distal3.119823.12997K562KHDRBS1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for GAB3 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for GAB3 is not available on ENCORE database.

  • 78 RBPs can affect the levels of GAB3.  








The Knockdown/knockout RNA-Seq assay for GAB3 is not available on ENCORE database.





78 RBPs can affect the gene expression of GAB3 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
GAB3ENSG00000160219.73578.075102664.469500.425204.463402.88030K562ABCF1
GAB3ENSG00000160219.71687.10070910.549000.889604.450602.23780K562ADAR
GAB3ENSG00000160219.71524.030701855.66060-0.284003.478202.85500K562AGGF1
GAB3ENSG00000160219.72382.283802025.954800.233602.381701.53870K562ATP5C1
GAB3ENSG00000160219.71991.455601668.706000.255003.333302.27680K562BCLAF1
GAB3ENSG00000160219.71257.38440891.661400.495804.530403.11220K562CCAR1
GAB3ENSG00000160219.72967.935902112.708000.490307.088204.69250K562CEBPZ
GAB3ENSG00000160219.73031.639102214.710000.452902.351601.38690K562CNOT7
GAB3ENSG00000160219.72228.061001801.393800.306603.025902.20660K562CPSF6
GAB3ENSG00000160219.71526.60060953.123000.679503.678501.47210K562CPSF7
GAB3ENSG00000160219.75906.591803639.633400.6984015.9488013.77620K562CELF1
GAB3ENSG00000160219.73584.306502428.457900.5616010.141707.81940K562DDX21
GAB3ENSG00000160219.71114.504601463.49670-0.393004.954903.16970K562DDX27
GAB3ENSG00000160219.7948.703301392.09000-0.553207.022505.26140K562DDX3X
GAB3ENSG00000160219.72033.728302452.56160-0.270203.554102.82820K562DDX47
GAB3ENSG00000160219.71416.71360998.254500.505004.678102.86430K562DHX30
GAB3ENSG00000160219.71596.716901016.341900.651603.606201.58230K562DNAJC2
GAB3ENSG00000160219.71105.961901496.71030-0.436503.889102.79360K562EFTUD2
GAB3ENSG00000160219.71115.369101721.71660-0.6263012.1070010.75610K562EIF2S2
GAB3ENSG00000160219.71064.305801602.28060-0.590204.658903.27440K562EIF3D
GAB3ENSG00000160219.71105.936101454.36570-0.395103.605702.67160K562EIF4A3
GAB3ENSG00000160219.71588.404601309.711600.278202.747101.59940K562EIF4B
GAB3ENSG00000160219.73798.222202960.103900.359606.250304.85520K562EIF4G2
GAB3ENSG00000160219.72389.154401667.520600.518707.408305.29700K562EXOSC5
GAB3ENSG00000160219.71278.904701025.087000.319102.813401.46030K562FUS
GAB3ENSG00000160219.71021.432501512.47490-0.566309.634908.58670K562FXR1
GAB3ENSG00000160219.72633.930501656.037500.6694015.0357012.72590K562GLRX3
GAB3ENSG00000160219.71865.036502294.47010-0.299002.722701.97150K562GRSF1
GAB3ENSG00000160219.73113.036701987.711500.647103.934401.80130K562HNRNPA0
GAB3ENSG00000160219.72486.806401861.073300.418105.113803.66960K562HNRNPA1
GAB3ENSG00000160219.72968.572402073.025700.517903.158901.46110K562HNRNPAB
GAB3ENSG00000160219.72780.373702216.449100.326902.818201.75040K562HNRNPL
GAB3ENSG00000160219.7868.124401575.35240-0.8597010.677308.56650K562HNRNPM
GAB3ENSG00000160219.71502.736102596.74820-0.7891013.0998011.41620K562HSPD1
GAB3ENSG00000160219.73523.124802429.713900.536004.564302.23490K562IGF2BP1
GAB3ENSG00000160219.73165.486002022.903800.645903.860702.15950K562ILF2
GAB3ENSG00000160219.71275.96150900.208400.503203.252501.63750K562KHDRBS1
GAB3ENSG00000160219.72483.462402049.185500.277202.541601.75500K562KIF1C
GAB3ENSG00000160219.71975.870901468.722900.427802.799401.85970K562KRR1
GAB3ENSG00000160219.71203.835001666.67880-0.469305.313404.13770K562MAGOH
GAB3ENSG00000160219.72238.249101678.754400.414904.686603.52650K562METAP2
GAB3ENSG00000160219.73852.449703155.182000.288002.466401.40120K562MSI2
GAB3ENSG00000160219.72513.985301741.092400.5299012.6336011.05420K562MTPAP
GAB3ENSG00000160219.71027.256301452.30530-0.499506.327604.49720K562NCBP2
GAB3ENSG00000160219.73649.137201934.594600.9154056.5618053.91720K562NSUN2
GAB3ENSG00000160219.73412.208302127.698400.681304.978103.29270K562PABPC1
GAB3ENSG00000160219.71074.197501483.01960-0.465304.752003.46090K562PCBP2
GAB3ENSG00000160219.73360.390202121.079400.663708.194106.76350K562PCBP3
GAB3ENSG00000160219.72236.286801626.940100.458806.071504.88890K562POLR2G
GAB3ENSG00000160219.7626.185201456.47760-1.2178022.4610020.31670K562PRPF8
GAB3ENSG00000160219.7795.237101619.24670-1.0259022.9141021.07520K562PTBP1
GAB3ENSG00000160219.71977.465403229.70140-0.7077011.528909.85800K562PUF60
GAB3ENSG00000160219.71138.791301914.97030-0.749809.869008.89170K562PUS1
GAB3ENSG00000160219.71433.596701142.000300.328004.237002.28850K562RPS10
GAB3ENSG00000160219.7816.768701483.41020-0.8609010.444308.82900K562RPS19
GAB3ENSG00000160219.71294.546601839.17100-0.506604.954903.56560K562RPS3
GAB3ENSG00000160219.72289.832801488.996300.620805.008003.21910K562RRP9
GAB3ENSG00000160219.72950.908802017.565100.548403.261701.59220K562SBDS
GAB3ENSG00000160219.73264.283601908.825300.7740022.9946020.85720K562SF3A3
GAB3ENSG00000160219.71785.14340982.003300.8621013.7924011.26740K562SLBP
GAB3ENSG00000160219.72397.730801955.621400.293904.566903.39810K562SRPK2
GAB3ENSG00000160219.7973.497601587.34750-0.7054011.132109.72630K562SRSF1
GAB3ENSG00000160219.73343.463502167.459000.6252011.228208.84640K562SRSF7
GAB3ENSG00000160219.72364.354501851.850900.352404.112202.24630K562SRSF9
GAB3ENSG00000160219.71552.504201196.032500.376204.683602.95100K562SSB
GAB3ENSG00000160219.73475.141402513.003700.467605.168703.27270K562SSRP1
GAB3ENSG00000160219.73478.303902298.474000.597606.976404.93260K562STAU1
GAB3ENSG00000160219.71210.871801631.86350-0.430505.127104.00150K562SYNCRIP
GAB3ENSG00000160219.71228.840001606.61600-0.386702.666601.97000K562TARDBP
GAB3ENSG00000160219.71848.314801294.926200.513204.837803.57020K562TIAL1
GAB3ENSG00000160219.71046.989801452.49080-0.472303.646802.35420K562U2AF1
GAB3ENSG00000160219.71198.816801500.08850-0.323403.082202.23420K562U2AF2
GAB3ENSG00000160219.72444.783002051.285000.253103.397502.60710K562UPF1
GAB3ENSG00000160219.72887.655602152.017200.424103.528402.16670K562UTP3
GAB3ENSG00000160219.72973.914401755.230700.760606.369605.00890K562WDR3
GAB3ENSG00000160219.72166.684401825.161200.247403.371102.44620K562WDR43
GAB3ENSG00000160219.71975.464701519.859200.378202.960201.69630K562XRN2
GAB3ENSG00000160219.74297.795902443.676500.814408.805807.14020K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for GAB3 is not available on ENCORE database.





3 RBPs can affect the splicing of GAB3 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEGAB3ENSG00000160219.7chrX-1539256841539258341539254061539254881539275681539277880.073000.001520.02942includedK562SRSF1
SEGAB3ENSG00000160219.7chrX-153943794153944031153941481153941701153944300153944604-0.133000.000700.09446excludedK562NPM1
A3SSGAB3ENSG00000160219.7chrX-1539414811539417011539414811539416981539443001539446040.412000.000140.05255longerK562FXR2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for GAB3 is not avaliable on ENCORE database.