PCBP3

General Information

Gene Name       : PCBP3
Gene ID             : ENSG00000183570.16
Essential Gene : No

Functions

Localization(RBPImage: PCBP3)

Domains (AlphaFold: PCBP3)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PCBP3ENSG00000183570.160.000.480.24ENCSR000AEF
HepG2PCBP3ENSG00000183570.160.000.000.00ENCSR985KAT
K562PCBP3ENSG00000183570.160.000.020.01ENCSR000AEO

Assays

1 Released experiments are available on ENCORE database.

Assay TypeExp_NameENCODE IDTarget labelBiosampleStatusLinked AntibodyControlsMethodNote
knockdown followed by RNA-seq PCBP3-BGKcLV06-K562ENCSR105LOVPCBP3K562ReleasedENCSR341TTW   CRISPRKD% = 48.6,56.1






  eCLIP  

No eCLIP experiment available



  Antibody Validation  
  GeneName    Antibody_DCC_ID    Product_ID    Lot_ID    Phosphate    HepG2 Primary Validation    K562 Primary Validation    HepG2 Secondary Validation    K562 Secondary Validation  
PCBP3ENCAB823NUIRN054PW1Released, ENCODE3BGKcLV06-23, Released, ENCODE3


  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
PCBP3K562shRNABGKLV11-33,BGKLV11-34BGKLV11-1,BGKLV11-20.0,0.0NotSatisfiedENCODE3
PCBP3K562CRISPRENCSR105LOVENCSR341TTWPCBP3-BGKcLV06-23,PCBP3-BGKcLV06-24NT-BGKcLV06-1,NT-BGKcLV06-248.6,56.1ReleasedENCODE3
PCBP3HepG2CRISPRBGHcLV07-23,BGHcLV07-24BGHcLV07-1,BGHcLV07-20.0,2.0NotSatisfiedENCODE3
PCBP3293TshRNAPCBP3-BG293LV04-43,PCBP3-BG293LV04-44NT-BG293LV04-1,NT-BG293LV04-2,SubmittingENCORE2
PCBP3293TshRNABG293LV04-45,BG293LV04-46BG293LV04-1,BG293LV04-2NotSatisfiedENCORE2
PCBP3293TshRNAPCBP3-BG293LV06-41,PCBP3-BG293LV06-42NT-BG293LV06-1,NT-BG293LV06-2,SequencedENCORE2


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  
    PCBP3: Click to RBP Image Database
  • Cytoplasm
  • Cytoskeleton
  • Actin
  • Cell Cortex












    • RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela
    PCBP3Product_ID: RN054PW
    Lot_ID: 1
    Source: MBLI
    Target Name: PCBP3-human    		 HepG2_MBL_RN054PW_001_PCBP3.png<br>Caption: IP-Western Blot analysis of HepG2 whole cell lysate using PCBP3 specific antibody. Lane 1 is 1% of twenty million whole cell lysate input and lane 2 is 25% of IP enrichment using rabbit normal IgG (lanes under 'IgG'). Lane 3 is 1% of twenty million whole cell lysate input and lane 4 is 10% IP enrichment using rabbit polyclonal anti-PCBP3 antibody (lanes under 'PCBP3').
    		 PCBP3-CRISPR-K562.png<br>Caption: Western blot following CRISPR against PCBP3 in K562 whole cell lysate using PCBP3 specific antibody. Lane 1 is a ladder, lane 2 is K562 non-targeting control knockdown, lane 3 and 4 are two different CRISPR against PCBP3. PCBP3 protein appears as the green arrow, Tubulin serves as a control and appears in red arrow.








    RNA Targets

    • eCLIP assay for PCBP3 is not avaliable on ENCORE database.



    Proteins bound to RNA

    • NO known proteins bind on PCBP3 RNA with finished eCLIP experiments on ENCORE database.





    eCLIP assay for PCBP3 is not avaliable on ENCORE database.






    NO known proteins are bound to PCBP3 RNA with finished eCLIP experiments on ENCORE database.





    eCLIP assay for PCBP3 is not avaliable on ENCORE database.



    Diffrential Expression
    • 5,123 differentially expressed genes after Knockdown/Knockout PCBP3 protein.  





    • No RBPs affect the gene expression of PCBP3 on ENCORE database.

    5,123 differentially expressed genes after Knockdown/Knockout PCBP3 protein :

    Only display 100 entries as example. Please click "View All" button to see all 5,123 entries.     

    Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
    DPM1ENSG00000000419.8952.160601238.00090-0.378702.592001.78920K562PCBP3
    CFHENSG00000000971.11982.436901352.41830-0.461103.618902.66690K562PCBP3
    FUCA2ENSG00000001036.91580.483101969.33290-0.317302.168301.43180K562PCBP3
    GCLCENSG00000001084.6588.10240372.130900.660204.729803.64450K562PCBP3
    STPG1ENSG00000001460.13413.58160255.548300.694504.285403.24900K562PCBP3
    LAS1LENSG00000001497.122516.462803381.42930-0.426203.773602.80170K562PCBP3
    SEMA3FENSG00000001617.7229.91660122.452300.908802.547601.74970K562PCBP3
    ANKIB1ENSG00000001629.51271.80490979.779800.376202.503001.71300K562PCBP3
    CYP51A1ENSG00000001630.111869.014503621.32860-0.9542012.0060010.27480K562PCBP3
    LAP3ENSG00000002549.81644.297902199.18050-0.419503.430102.50300K562PCBP3
    ICA1ENSG00000003147.13706.90490489.005600.531603.625102.67230K562PCBP3
    ALS2ENSG00000003393.101259.04930830.337700.600504.095203.08150K562PCBP3
    CFLARENSG00000003402.152020.714602704.43350-0.420503.551702.61000K562PCBP3
    TFPIENSG00000003436.105305.751802363.655501.1664024.2479021.92790K562PCBP3
    RBM5ENSG00000003756.123136.885402528.706600.310802.178301.44020K562PCBP3
    SARM1ENSG00000004139.977.6607021.823101.831205.484904.30780K562PCBP3
    PLXND1ENSG00000004399.8296.34680740.86960-1.3219017.3566015.33240K562PCBP3
    AK2ENSG00000004455.128956.7224013684.42070-0.611507.990406.57780K562PCBP3
    FKBP4ENSG00000004478.53058.207905224.31540-0.7726011.488909.79300K562PCBP3
    KDM1AENSG00000004487.114343.588505582.10860-0.361903.074002.19660K562PCBP3
    CAMKK1ENSG00000004660.1057.02640178.05150-1.642609.860808.29640K562PCBP3
    SLC25A13ENSG00000004864.91258.397901729.01490-0.458403.863702.88120K562PCBP3
    SLC4A1ENSG00000004939.97449.738802673.449201.4784039.2444036.54490K562PCBP3
    UPF1ENSG00000005007.82370.778703216.16260-0.440003.880802.89600K562PCBP3
    SKAP2ENSG00000005020.8605.73470427.466200.502803.097102.21580K562PCBP3
    SLC25A5ENSG00000005022.53715.801508017.31860-1.1094023.0989020.81230K562PCBP3
    DHX33ENSG00000005100.8641.78770948.11270-0.563004.556603.49130K562PCBP3
    LIG3ENSG00000005156.71170.624101952.16690-0.737808.939207.44860K562PCBP3
    ACSM3ENSG00000005187.7787.938402066.18120-1.3908028.2817025.83790K562PCBP3
    AC004381.6ENSG00000005189.152010.792101277.964900.653807.192005.85060K562PCBP3
    FAM214BENSG00000005238.15476.08840271.018200.812706.098604.85890K562PCBP3
    MSL3ENSG00000005302.131296.050601018.774800.347202.216201.47240K562PCBP3
    WDR54ENSG00000005448.12300.40790138.939501.112407.659906.27600K562PCBP3
    CROTENSG00000005469.7146.3995077.448400.918503.330202.41800K562PCBP3
    RHBDD2ENSG00000005486.121111.95160614.829800.854703.522402.58360K562PCBP3
    IBTKENSG00000005700.10684.745501165.46950-0.767308.277606.84110K562PCBP3
    ZNF195ENSG00000005801.12794.069801065.62380-0.424402.561001.76130K562PCBP3
    FBXL3ENSG00000005812.6491.87770329.141300.579503.458002.52630K562PCBP3
    PDK2ENSG00000005882.799.7195031.983301.640504.316503.27640K562PCBP3
    ITGA2BENSG00000005961.13158.44550447.15210-1.4968011.8725010.15330K562PCBP3
    MAP3K14ENSG00000006062.9138.15540213.52760-0.628102.049901.33440K562PCBP3
    TNFRSF12AENSG00000006327.9107.18530339.66410-1.6640016.2128014.25230K562PCBP3
    JHDM1DENSG00000006459.61218.18300909.242400.421902.947902.08900K562PCBP3
    TBXA2RENSG00000006638.752.51510182.66020-1.798408.953407.46230K562PCBP3
    VPS41ENSG00000006715.111213.63460894.548000.440002.959302.09890K562PCBP3
    ELAC2ENSG00000006744.141413.597901993.12000-0.495704.445403.39240K562PCBP3
    SCINENSG00000006747.101799.13730990.209800.8614011.301109.62300K562PCBP3
    CDKL3ENSG00000006837.753.1134023.811201.157302.141601.40890K562PCBP3
    CCDC124ENSG00000007080.6610.01330967.97580-0.666103.206202.31090K562PCBP3
    DNAH9ENSG00000007174.1315.651801.309303.579402.704001.88160K562PCBP3
    KIAA0100ENSG00000007202.106573.304109122.65480-0.472805.011503.89180K562PCBP3
    TRAPPC6AENSG00000007255.6192.34370101.308000.924803.402602.47900K562PCBP3
    MATKENSG00000007264.9100.11130386.41440-1.9485022.4486020.19300K562PCBP3
    ST7LENSG00000007341.14542.44970389.929400.476202.692901.87350K562PCBP3
    TKTL1ENSG00000007350.12267.00220152.155400.811204.292003.25480K562PCBP3
    RHBDF1ENSG00000007384.11582.25710441.675200.398602.151301.41680K562PCBP3
    LUC7LENSG00000007392.121012.692301364.74180-0.430403.223502.32550K562PCBP3
    CACNA2D2ENSG00000007402.778.5186033.558501.226302.746501.91870K562PCBP3
    DNAJC11ENSG00000007923.112522.827203406.48330-0.433203.907202.91860K562PCBP3
    PSMB1ENSG00000008018.83917.437205305.15410-0.437504.186603.16220K562PCBP3
    CDK11AENSG00000008128.183316.108702157.182000.620207.265805.91820K562PCBP3
    NADKENSG00000008130.111559.139902028.45110-0.379602.784201.95030K562PCBP3
    CYB561ENSG00000008283.11531.85450692.63890-0.381102.099501.37480K562PCBP3
    MGST1ENSG00000008394.8389.26200574.98870-0.562803.692002.72890K562PCBP3
    RHOBTB2ENSG00000008853.12168.9665072.064201.229305.920304.69720K562PCBP3
    RPS20ENSG00000008988.59309.7524017500.10050-0.9105016.6386014.65780K562PCBP3
    CSDE1ENSG00000009307.1113674.8785019060.08890-0.479005.253004.10350K562PCBP3
    REV3LENSG00000009413.111643.514001045.299400.652806.747605.44590K562PCBP3
    TENM1ENSG00000009694.93305.290501654.962500.9979016.9403014.93330K562PCBP3
    FAM76AENSG00000009780.11253.74890174.584800.539402.177801.43980K562PCBP3
    POMT2ENSG00000009830.7193.27550348.17270-0.849104.655003.57730K562PCBP3
    MLXIPLENSG00000009950.11450.02690253.584300.827403.328102.41630K562PCBP3
    BAZ1BENSG00000009954.66699.922808594.85150-0.359303.069902.19320K562PCBP3
    METTL13ENSG00000010165.151065.630901347.27970-0.338302.168601.43200K562PCBP3
    UQCRC1ENSG00000010256.62394.938703103.83840-0.374103.008802.14180K562PCBP3
    STAB1ENSG00000010327.638.8542080.04290-1.042702.496901.70760K562PCBP3
    IDSENSG00000010404.131658.509601245.832600.412703.112502.22910K562PCBP3
    BTKENSG00000010671.111756.158702468.79470-0.491404.587203.51780K562PCBP3
    FYNENSG00000010810.13615.85320412.916800.576603.868602.88530K562PCBP3
    TCEB3ENSG00000011007.82149.725302684.18170-0.320302.274901.52080K562PCBP3
    LYPLA2ENSG00000011009.61351.319401967.78780-0.542205.058003.93330K562PCBP3
    CLCN6ENSG00000011021.17893.890101297.03670-0.537004.534303.47190K562PCBP3
    ABHD5ENSG00000011198.33068.279701985.364800.627907.350405.99310K562PCBP3
    AKAP8LENSG00000011243.133830.871203123.889000.294202.092601.36900K562PCBP3
    UTP18ENSG00000011260.9431.10240700.90770-0.701205.933504.70920K562PCBP3
    RNF216ENSG00000011275.142121.869101719.728800.303102.014001.30530K562PCBP3
    PTBP1ENSG00000011304.125304.912509714.57320-0.8728012.2409010.49970K562PCBP3
    SYT7ENSG00000011347.580.3982027.521601.546504.465503.41060K562PCBP3
    LARS2ENSG00000011376.51284.258701859.01070-0.533605.003303.88460K562PCBP3
    PIK3C2AENSG00000011405.91890.257701509.883500.324002.131201.40000K562PCBP3
    ANLNENSG00000011426.63362.708802562.363800.392003.223002.32530K562PCBP3
    QPCTLENSG00000011478.7117.12380341.99270-1.5459014.7114012.83110K562PCBP3
    PPP5CENSG00000011485.101663.005302867.21040-0.7859010.686009.05440K562PCBP3
    CEP68ENSG00000011523.91112.59170587.356600.9215010.982809.32930K562PCBP3
    BRCA1ENSG00000012048.153706.106102958.598000.324902.383701.61310K562PCBP3
    ERCC1ENSG00000012061.111177.423101797.59020-0.610406.164104.91870K562PCBP3
    CD22ENSG00000012124.10126.85590275.94120-1.121207.578806.20290K562PCBP3
    PRICKLE3ENSG00000012211.8638.57400924.23480-0.533402.595401.79210K562PCBP3
    ELOVL5ENSG00000012660.94402.251906396.92940-0.539106.103804.86380K562PCBP3
    CALCOCO1ENSG00000012822.111573.04420847.674900.8919011.7799010.06710K562PCBP3
    Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

    *: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
    **: "-log(0)" was displayed as "99999.99999".






    No RBPs affect the gene expression of PCBP3 on ENCORE database.






    The Knockdown/knockout RNA-Seq assay for PCBP3 is not available on ENCORE database.






    No RBPs affect the alternative splcing events of PCBP3 on ENCORE database.





    The Knockdown/knockout RNA-Seq assay for PCBP3 is not avaliable on ENCORE database.