BTK

General Information

Gene Name       : BTK
Gene ID             : ENSG00000010671.15
Essential Gene : No

Functions

Localization

Domains (AlphaFold: BTK)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878BTKENSG00000010671.15120.57104.47112.52ENCSR000AEF
HepG2BTKENSG00000010671.150.000.000.00ENCSR985KAT
K562BTKENSG00000010671.1556.3555.4055.88ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for BTK is not avaliable on ENCORE database.



Proteins bound to RNA
  • BTK RNA is bound by 13 proteins.  







eCLIP assay for BTK is not avaliable on ENCORE database.





13 proteins are bound to BTK RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chrX100604469100604551-3'-UTR,intron-Distal4.244918.65625K562DDX6
chrX100604560100604618-3'-UTR,intron-Distal4.5703916.56181K562PUM2
chrX100604822100604881-3'-UTR,CDS,intron-Distal5.106236.79809K562PABPC4
chrX100604456100604538-3'-UTR,intron-Distal4.204203.34382K562APOBEC3C
chrX100604496100604699-3'-UTR,intron-Distal3.139467.93427K562UPF1
chrX100613335100613425-CDS,intron-Distal,intron-Proximal4.595736.30966K562YBX3
chrX100629587100629623-CDS,intron-Distal,intron-Proximal4.734655.24929K562ZNF622
chrX100624986100625065-CDS,intron-Distal3.290308.83088K562DDX24
chrX100615563100615593-CDS,intron-Distal3.815254.50825K562DDX24
chrX100630131100630156-CDS,intron-Distal,intron-Proximal3.510433.07653K562ZNF622
chrX100615700100615738-CDS,intron-Distal4.468965.64870K562DDX24
chrX100617584100617613-CDS,intron-Distal3.405556.61971K562YBX3
chrX100608966100609029-CDS,intron-Distal,intron-Proximal3.786759.96904K562SF3B4
chrX100629590100629623-CDS,intron-Distal,intron-Proximal3.897005.20093K562DDX24
chrX100630153100630207-CDS,intron-Distal3.467565.32768K562YBX3
chrX100624992100625068-CDS,intron-Distal,intron-Proximal4.9988817.98612K562PUM2
chrX100617630100617669-CDS,intron-Distal3.132456.82055K562YBX3
chrX100617612100617649-CDS,intron-Distal3.589064.40383K562UCHL5
chrX100609573100609668-CDS,intron-Distal,intron-Proximal4.4896217.96981K562PRPF8
chrX100611786100611902-CDS,intron-Distal,intron-Proximal3.106133.85473K562GRWD1
chrX100617616100617649-CDS,intron-Distal4.928505.79396K562DDX24
chrX100611017100611090-CDS,intron-Distal,intron-Proximal3.963088.04012K562ZNF622
chrX100611003100611191-CDS,intron-Distal,intron-Proximal3.220954.85211K562GRWD1
chrX100626599100626636-CDS,intron-Distal,intron-Proximal3.953183.02181K562PRPF8
chrX100630207100630265-CDS,intron-Distal3.966297.64164K562YBX3
chrX100626619100626690-CDS,intron-Distal,intron-Proximal4.522779.64961K562DDX24
chrX100624987100625062-CDS,intron-Distal4.075258.70187K562ZNF622
chrX100609680100609733-CDS,intron-Distal,intron-Proximal4.509704.42765K562SF3B4
chrX100640186100640284-intron-Distal5.169354.90095K562PTBP1
chrX100609319100609434-intron-Distal4.4355715.52420K562PTBP1
chrX100640058100640111-intron-Distal4.343323.42734K562PTBP1
chrX100609434100609518-intron-Distal3.833595.81842K562PTBP1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for BTK is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for BTK is not available on ENCORE database.

  • 35 RBPs can affect the levels of BTK.  








The Knockdown/knockout RNA-Seq assay for BTK is not available on ENCORE database.





35 RBPs can affect the gene expression of BTK :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
BTKENSG00000010671.111497.910303113.46460-1.0556023.1955021.68160K562AQR
BTKENSG00000010671.111794.956702283.58440-0.347404.851603.02960K562BCCIP
BTKENSG00000010671.112012.759002573.49610-0.354602.989402.08070K562BOP1
BTKENSG00000010671.111382.664801674.08580-0.275902.595501.57650K562CSTF2
BTKENSG00000010671.114181.125403706.975500.173502.014901.44330K562DDX47
BTKENSG00000010671.111466.477301814.55830-0.307302.269501.44320K562EFTUD2
BTKENSG00000010671.111259.724701604.87080-0.349302.995002.14360K562EIF4A3
BTKENSG00000010671.112528.621601935.393300.385603.160401.93860K562FKBP4
BTKENSG00000010671.111215.778701668.99510-0.457106.949506.05140K562FXR1
BTKENSG00000010671.112501.371503295.96120-0.398004.852203.85300K562GRSF1
BTKENSG00000010671.111752.443502465.03820-0.492206.912505.26720K562HNRNPA1
BTKENSG00000010671.111695.227502230.26810-0.395704.273803.54800K562HNRNPC
BTKENSG00000010671.113043.016802396.935400.344202.753601.52230K562HNRNPK
BTKENSG00000010671.112096.752502729.71430-0.380605.534004.25650K562HNRNPU
BTKENSG00000010671.112985.553503761.49320-0.333303.063502.22820K562HSPD1
BTKENSG00000010671.111576.321302522.12970-0.6781011.394209.61010K562MAGOH
BTKENSG00000010671.111996.331502517.05910-0.334403.465502.41730K562MATR3
BTKENSG00000010671.111617.416102550.21270-0.656909.092807.43190K562METAP2
BTKENSG00000010671.112102.094202648.22860-0.333205.704904.57060K562MTPAP
BTKENSG00000010671.111862.407602465.23170-0.404605.004203.12650K562PCBP1
BTKENSG00000010671.111757.754102244.12610-0.352403.359402.28280K562PCBP2
BTKENSG00000010671.111756.158702468.79470-0.491404.587203.51780K562PCBP3
BTKENSG00000010671.111362.340601893.63530-0.475106.144004.95620K562POLR2G
BTKENSG00000010671.111302.561301765.77720-0.439003.960003.06400K562PRPF8
BTKENSG00000010671.111786.162102450.38430-0.456106.083205.13060K562PTBP1
BTKENSG00000010671.113577.626704862.13340-0.442605.679204.51420K562PUF60
BTKENSG00000010671.111926.857402349.79130-0.286302.268301.51200K562RBM22
BTKENSG00000010671.111501.349501824.03720-0.280902.346801.43730K562RCC2
BTKENSG00000010671.111549.591402038.31390-0.395504.761203.62800K562SF3B4
BTKENSG00000010671.111344.873401729.17350-0.362603.097201.99780K562SRFBP1
BTKENSG00000010671.112869.877902402.159600.256602.358701.69810K562SRSF1
BTKENSG00000010671.111573.002902431.21550-0.628208.056706.77210K562TARDBP
BTKENSG00000010671.111693.393002345.16260-0.469806.183004.88900K562TIA1
BTKENSG00000010671.111859.375302301.12870-0.307502.495701.47010K562TRA2A
BTKENSG00000010671.112274.665602776.09490-0.287404.961203.85770K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for BTK is not available on ENCORE database.






No RBPs affect the alternative splcing events of BTK on ENCORE database.





The Knockdown/knockout RNA-Seq assay for BTK is not avaliable on ENCORE database.