METAP2

General Information

Gene Name       : METAP2
Gene ID             : ENSG00000111142.13
Essential Gene : Yes

Functions

Localization(RBPImage: METAP2)

Domains (AlphaFold: METAP2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878METAP2ENSG00000111142.1395.7789.6392.70ENCSR000AEF
HepG2METAP2ENSG00000111142.1377.31108.0192.66ENCSR985KAT
K562METAP2ENSG00000111142.13142.37130.90136.63ENCSR000AEO

Assays

3 Released experiments are available on ENCORE database.

Assay TypeExp_NameENCODE IDTarget labelBiosampleStatusLinked AntibodyControlsMethodNote
eCLIPeCLIP: 509ENCSR303OQDMETAP2K562ReleasedENCAB441VBJENCSR750NTM  
knockdown followed by RNA-seq METAP2-BGKLV36-K562ENCSR952QDQMETAP2K562ReleasedENCSR424QCW   shRNAKD% = 51.6,50.9
knockdown followed by RNA-seq METAP2-BGHLV16-HepG2ENCSR992JGEMETAP2HepG2ReleasedENCSR689PHN   shRNAKD% = 92.3,92.0






  eCLIP  
  RBP    Exp_UID    Cell_Line    ENCODE_ACCESSION    Control_ENCODE_ACCESSION    ENCODE_Antibody_ID    Antibody    Lot_num    Status    Project  
METAP2509K562ENCSR303OQDENCSR750NTMENCAB441VBJA303-419A1ReleasedENCODE3


  Antibody Validation  
  GeneName    Antibody_DCC_ID    Product_ID    Lot_ID    Phosphate    HepG2 Primary Validation    K562 Primary Validation    HepG2 Secondary Validation    K562 Secondary Validation  
METAP2ENCAB441VBJA303-419A1Released, ENCODE3BGHLV16-33, Released, ENCODE3BGKLV36-35, Released, ENCODE3


  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
METAP2K562shRNABGKLV19-33,BGKLV19-34BGKLV19-1,BGKLV19-2redo transduction,redo transductionNotSatisfiedENCODE3
METAP2K562shRNABGKLV21-33,BGKLV21-34BGKLV21-1,BGKLV21-20.0,20.6NotSatisfiedENCODE3
METAP2K562shRNAENCSR952QDQENCSR424QCWMETAP2_BGKLV36-35,METAP2_BGKLV36-36NT_BGKLV36-1,NT_BGKLV36-251.6,50.9ReleasedENCODE3
METAP2HepG2shRNAENCSR992JGEENCSR689PHNMETAP2_BGHLV16_33,METAP2_BGHLV16_34NT_BGHLV16_1,NT_BGHLV16_292.3,92.0ReleasedENCODE3


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  
    METAP2: Click to RBP Image Database
  • Nuclei
  • PML bodies
  • Cytoplasm
  • Compartment/Organelle
  • Unknown Cyto Foci
  • Cytosolic
  • Cell Cortex












    • RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela
    METAP2Product_ID: A303-419A
    Lot_ID: 1
    Source: Bethyl Labs
    Target Name: METAP2-human    		 MetAP2_Secondary_Western.png<br>Caption: Western blot following shRNA against MetAP2 in HepG2 whole cell lysate using MetAP2 specific antibody. Lane 1 is a ladder, lane 2 is HepG2 non-targeting control knockdown, lane 3 and 4 are two different shRNAs against MetAP2. MetAP2 protein appears as the green band, Tubulin serves as a control and appears in red.
    		 k562_bethyl_A303-419A_1_MeTAP2.png<br>Caption: IP-Western Blot analysis of K562 whole cell lysate using METAP2 specific antibody. Lane 1 is 1% of twenty million whole cell lysate input and lane 2 is 25% of IP enrichment using rabbit normal IgG (lanes under 'IgG'). Lane 3 is 1% of twenty million whole cell lysate input and lane 4 is 10% IP enrichment using rabbit polyclonal anti-METAP2 antibody (lanes under 'METAP2').
    		 METAP2-K562.png<br>Caption: Western blot following shRNA against METAP2 in K562 whole cell lysate using METAP2 specific antibody. Lane 1 is a ladder, lane 2 is K562 non-targeting control knockdown, lane 3 and 4 are two different shRNA against METAP2.METAP2 protein appears as the green band, Tubulin serves as a control and appears in red.








    RNA Targets
    • METAP2 protein binds to 3,055 RNA regions.  





    Proteins bound to RNA
    • METAP2 RNA is bound by 28 proteins.  






    METAP2 protein has 3,055 RNA targets:

    Only display 100 entries as example. Please click "View All" button to see all 3,055 entries.     

    RBP Chr Start End Strand log2(fold change) -log(p-value) Cell Line Matched Gene Matched Area
    METAP2chr1270747497074794-3.220745.18855K562PHB23'-UTR,intron-Distal,intron-Proximal
    METAP2chr35326449053264527-4.7618320.65798K562TKT3'-UTR,CDS,intron-Distal
    METAP2chr177982641479826460-3.421565.40265K562ARHGDIA3'-UTR,CDS,intron-Distal,intron-Proximal
    METAP2chr191113262411132640+3.648424.17219K562SMARCA4CDS
    METAP2chr189263378926344-3.0444816.15529K562ENO1CDS,intron-Distal,intron-Proximal
    METAP2chr9134361471134361502+3.375965.36360K562PRRC2BCDS,intron-Proximal
    METAP2chr191457838114578429+3.087054.67166K562PKN1CDS
    METAP2chr14316259043162615+3.7549179.22643K562YBX1CDS
    METAP2chr174117080041170817-4.016446.03462K562VAT13'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal
    METAP2chr3127790102127790182+3.977444.44179K562SEC61A13'-UTR
    METAP2chr195092107850921273+3.365253.71087K562CTD-2545M3.6, POLD13'-UTR,CDS,intron-Distal,intron-Proximal,polyA_site
    METAP2chr1266458756645883+4.9441457.05269K562GAPDH3'-UTR,CDS
    METAP2chr178004355980043569-5.4552017.74031K562FASNCDS,intron-Distal,intron-Proximal
    METAP2chr29753404997534068-3.542674.17219K562SEMA4Cintron-Distal
    METAP2chr16765887765974+4.558764.65678K562METRNCDS
    METAP2chr193489064534890684+3.5120726.69925K562RP11-618P17.4, GPICDS,intron-Distal
    METAP2chr1978617978664+3.127035.59887K562AGRNCDS,intron-Proximal
    METAP2chr159141891691418965+4.8695720.32759K562FURIN3'-UTR,5'-UTR
    METAP2chr14102547739102547771-3.492137.00784K562HSP90AA13'-UTR,intron-Distal
    METAP2chr81168902611689065+3.752005.72417K562FDFT13'-UTR,CDS,intron-Proximal
    METAP2chr7150649521150649543-3.6140816.94002K562KCNH2CDS,intron-Distal
    METAP2chr11812534812537+3.5301274.64913K562RPLP2CDS,intron-Proximal
    METAP2chr177989254379892557-4.468483.35417K562PYCR1CDS,intron-Distal,intron-Proximal
    METAP2chr8144990269144990305-3.320754.24648K562PLEC3'-UTR,intron-Distal,intron-Proximal
    METAP2chr7128485199128485268+4.0564017.87462K562FLNCCDS
    METAP2chr193992396139924039-3.7197328.00816K562RPS163'-UTR,CDS,intron-Distal,intron-Proximal
    METAP2chr8144994040144994130-3.647256.72681K562PLECCDS,intron-Distal
    METAP2chr108196514681965262-3.098745.31732K562ANXA115'-UTR,intron-Distal
    METAP2chr67422909574229144-3.1046354.22066K562EEF1A1CDS,intron-Distal,intron-Proximal
    METAP2chr14316770343167725+3.9591258.71598K562YBX13'-UTR
    METAP2chr174044142840441450+3.198193.09251K562STAT5A5'-UTR,CDS,intron-Distal
    METAP2chr63420504334205073+3.8708625.12059K562HMGA15'-UTR,intron-Distal
    METAP2chr1956914415691465+3.0022514.09350K562RPL36CDS,intron-Proximal
    METAP2chr74415754244157582-3.579676.08728K562POLD2CDS,intron-Distal
    METAP2chr195906077059060820+3.3734413.24885K562TRIM28CDS
    METAP2chr159063478590634795-3.322383.25727K562IDH2CDS,intron-Distal
    METAP2chrX153582983153583023-4.1208223.35414K562FLNA3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal
    METAP2chr1916221721622222-3.835159.33771K562TCF3CDS,intron-Distal,intron-Proximal
    METAP2chr7150068617150068682+5.9362111.39560K562REPIN1, ZNF7753'-UTR,CDS,intron-Distal
    METAP2chrX5357801053578081-3.638997.28797K562HUWE1CDS,intron-Distal
    METAP2chr189319598932005-3.5707027.58175K562ENO1CDS,intron-Distal
    METAP2chr177549483275494934+4.1734919.11431K562SEPT93'-UTR,intron-Proximal
    METAP2chr10102107105102107133+3.367516.34575K562SCD5'-UTR
    METAP2chr204870551448705616-5.1389922.70218K562TMEM189-UBE2V1, TMEM189, UBE2V1intron-Distal
    METAP2chr195618666456186756+3.254924.20168K562EPN15'-UTR
    METAP2chr63160997331610030-4.4783918.89507K562BAG6CDS,intron-Distal,intron-Proximal
    METAP2chr1920392562039293-3.468485.72417K562MKNK23'-UTR,intron-Distal
    METAP2chr8145623286145623341-3.585019.15420K562CPSF1CDS,intron-Distal
    METAP2chr13680702336807071-3.937785.92795K562STK403'-UTR,intron-Distal
    METAP2chr1620142782014294-4.7746829.17262K562RPS2CDS,intron-Distal
    METAP2chr419783251978405+4.592445.27753K562WHSC13'-UTR,CDS
    METAP2chr8146015840146015850-4.3307326.72790K562RPL83'-UTR,CDS,intron-Distal
    METAP2chr195905717159057199+3.093426.85736K562TRIM28CDS,intron-Distal
    METAP2chr174670341646703470-3.682734.73981K562HOXB9, HOXB7CDS,intron-Distal
    METAP2chr8146016765146016831-3.9431384.55407K562RPL8CDS,intron-Distal,intron-Proximal
    METAP2chr174924729649247331+4.0901119.88362K562NME2, NME1-NME2CDS,intron-Distal,intron-Proximal
    METAP2chr222423697924237014+3.547644.92959K562AP000350.10, MIFCDS
    METAP2chr5154195630154195670+3.626236.91717K562LARP13'-UTR
    METAP2chr11812560812573+3.2021162.32808K562RPLP2CDS
    METAP2chr1120177472017753-5.983358.67251K562H19intron-Distal,intron-Proximal
    METAP2chr177947795379477960-4.1091217.21876K562ACTG13'-UTR,CDS,intron-Distal,intron-Proximal
    METAP2chr193614547536145523+3.792808.41482K562COX6B1CDS,intron-Distal
    METAP2chr177539818975398328+3.158767.32416K562SEPT93'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal
    METAP2chr194131396941314047+3.017533.44337K562EGLN2, RAB4B-EGLN2, CTC-490E21.123'-UTR,intron-Distal,intron-Proximal
    METAP2chr162884735428847383+3.214405.88088K562ATXN2L3'-UTR,CDS
    METAP2chr1234744619234744680-4.0185410.57674K562IRF2BP2CDS,intron-Distal
    METAP2chr20464549464653-3.579673.25727K562CSNK2A13'-UTR,CDS,intron-Distal
    METAP2chr12120635126120635196-5.41642400.00000K562RPLP03'-UTR,CDS,intron-Distal,intron-Proximal
    METAP2chr177989059579890651-3.812507.22239K562PYCR13'-UTR,intron-Distal
    METAP2chr118577277085772887-4.6121632.28864K562PICALMintron-Distal
    METAP2chr11186139011861442-3.643724.14411K562MTHFRCDS,intron-Distal
    METAP2chr8145114944145114972-3.974463.03355K562OPLAH5'-UTR,intron-Distal
    METAP2chr12098016820980250-3.553448.71103K562DDOSTCDS,intron-Distal
    METAP2chr163008081930080823+4.1828159.08514K562ALDOACDS,intron-Proximal
    METAP2chr1266461606646173+4.4118057.79550K562GAPDHCDS
    METAP2chrX153759709153759805-3.022048.71433K562G6PD3'-UTR,intron-Distal
    METAP2chr1914083381408371+3.846517.18979K562DAZAP1intron-Distal
    METAP2chr11047952410479593+4.168957.83352K562PGDCDS
    METAP2chr191291100712911080-3.352815.40265K562PRDX2, HOOK2CDS,intron-Distal,intron-Proximal
    METAP2chr194185917841859268-4.010449.02930K562TGFB15'-UTR,intron-Distal
    METAP2chr756436285643661+3.520428.08424K562FSCN1CDS
    METAP2chr12133127050133127101+4.157733.35417K562FBRSL1intron-Distal
    METAP2chr189240858924098-3.2395223.65586K562ENO1CDS,intron-Distal
    METAP2chr168887297788873016+4.284617.83352K562CDT1CDS
    METAP2chr5180665099180665140-4.0185651.00466K562GNB2L13'-UTR,CDS,intron-Distal,intron-Proximal
    METAP2chr174115468941154711+3.036208.55827K562RPL27CDS,intron-Proximal
    METAP2chr1951440385144094+4.094973.67707K562KDM4BCDS
    METAP2chrX153593811153593842-4.2048519.69052K562FLNACDS,intron-Distal
    METAP2chr178055936080559457+4.744754.65678K562FOXK23'-UTR,CDS
    METAP2chr193992627939926297-3.6824226.15847K562RPS16CDS,intron-Distal,intron-Proximal
    METAP2chr7150648021150648117-3.5936934.87015K562KCNH2CDS,intron-Distal
    METAP2chr168567244385672524+4.003676.22231K562GSE1intron-Distal
    METAP2chr1963618776361939+5.508669.01147K562CLPP5'-UTR,CDS,intron-Proximal
    METAP2chr116478604264786121+3.114875.48666K562ARL2, RP11-399J13.3CDS,intron-Proximal
    METAP2chr161880156118801613-3.542673.25727K562RPS15A, RP11-1035H13.35'-UTR,intron-Distal,intron-Proximal
    METAP2chr33805147438051535-3.614874.17219K562PLCD1CDS,intron-Distal,intron-Proximal
    METAP2chr5180668491180668496-3.854078.35256K562GNB2L15'-UTR,CDS,intron-Distal,intron-Proximal
    METAP2chr3184046424184046495+3.599994.44179K562EIF4G1, EIF2B53'-UTR,CDS,intron-Distal
    METAP2chr108590994285909996+3.240645.31732K562GHITMCDS
    METAP2chr223742062637420695+5.138994.65678K562MPSTCDS




    28 proteins are bound to METAP2 RNA:

    Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
    chr129590794595908008+3'-UTR6.3134210.21115HepG2SUB1
    chr129590658195906640+3'-UTR,CDS5.1172213.83301HepG2BCLAF1
    chr129590660695906645+3'-UTR,CDS3.791776.61082K562GRWD1
    chr129590800895908066+3'-UTR5.702239.98281HepG2SUB1
    chr129590666795906693+3'-UTR,CDS,intron-Proximal5.430568.75808HepG2BCLAF1
    chr129590743095907439+3'-UTR,CDS3.800623.87469HepG2BCLAF1
    chr129590788595907955+3'-UTR3.576825.23915K562IGF2BP1
    chr129590657695906652+3'-UTR,CDS,intron-Proximal4.8338425.06147K562UCHL5
    chr129590758995907649+3'-UTR,CDS4.2623115.14256K562YBX3
    chr129590764995907668+3'-UTR,CDS3.871599.25117K562YBX3
    chr129590659195906632+3'-UTR,CDS4.8806010.96138K562ZNF622
    chr129590657795906698+3'-UTR,CDS,intron-Proximal3.684645.48237HepG2G3BP1
    chr129590766895907702+3'-UTR,CDS3.9943815.51230K562YBX3
    chr129590657795906667+3'-UTR,CDS4.247833.25521K562LIN28B
    chr129586789695867941+5'-UTR3.341143.81194K562TRA2A
    chr129586792995868015+5'-UTR,CDS3.233827.42139HepG2NCBP2
    chr129586792295868010+5'-UTR,CDS3.7050520.21916K562ZNF622
    chr129586794195868009+5'-UTR,CDS3.017266.69540K562TRA2A
    chr129586793495868003+5'-UTR,CDS3.756579.25963HepG2GRWD1
    chr129586988095869945+CDS,intron-Distal,intron-Proximal4.142743.06106HepG2TRA2A
    chr129587704795877057+CDS,intron-Distal,intron-Proximal4.709015.11007HepG2GRWD1
    chr129587699095877057+CDS,intron-Distal,intron-Proximal4.7910721.54533HepG2BCLAF1
    chr129588783895887934+CDS3.3416330.93449K562ZNF800
    chr129588873095888767+CDS,intron-Proximal3.822829.43524HepG2BCLAF1
    chr129587704895877057+CDS,intron-Distal,intron-Proximal4.4511320.84762K562ZNF622
    chr129586988995869941+CDS,intron-Distal,intron-Proximal5.299918.37142K562TRA2A
    chr129588787495887946+CDS3.9070517.91382HepG2BCLAF1
    chr129590567095905696+CDS,intron-Distal,intron-Proximal3.557624.44254K562GRWD1
    chr129587965495879709+CDS,intron-Proximal3.7794620.45628HepG2BCLAF1
    chr129587699095877048+CDS,intron-Distal,intron-Proximal4.6714543.68880K562ZNF622
    chr129586984095869876+CDS,intron-Distal,intron-Proximal4.044295.89850HepG2AQR
    chr129588875795888817+CDS4.7039222.58451K562UCHL5
    chr129586800595868103+CDS3.081253.89260K562LIN28B
    chr129587705095877057+CDS,intron-Distal,intron-Proximal3.3953510.18882K562GRWD1
    chr129587698895877057+CDS,intron-Distal,intron-Proximal3.305018.09342K562MTPAP
    chr129588783195887954+CDS,intron-Proximal3.273804.88178HepG2FXR2
    chr129587965495879697+CDS,intron-Proximal3.751743.32907K562SRSF7
    chr129586808495868106+CDS5.322827.95223HepG2BCLAF1
    chr129586990795869953+CDS,intron-Distal,intron-Proximal3.777705.10069HepG2GRWD1
    chr129588783195887875+CDS,intron-Proximal5.087066.46081K562TRA2A
    chr129586801195868066+CDS3.4090719.40295K562UCHL5
    chr129588777995887884+CDS,intron-Proximal3.135728.79250K562SF3B4
    chr129588872695888766+CDS,intron-Proximal3.990945.51636K562GPKOW
    chr129588787895887990+CDS3.2562711.66248HepG2AQR
    chr129587698895877059+CDS,intron-Distal,intron-Proximal3.8207319.43991K562CPSF6
    chr129587965395879693+CDS,intron-Proximal4.415554.10368HepG2TRA2A
    chr129587699295877058+CDS,intron-Distal,intron-Proximal3.400964.07060HepG2ZNF800
    chr129588980695889876+CDS,intron-Proximal4.654855.00488K562LIN28B
    chr129588788995887949+CDS4.3677713.34751HepG2GRWD1
    chr129586800995868074+CDS3.050664.97135K562TRA2A
    chr129590567195905712+CDS,intron-Distal3.5975512.85864K562UCHL5
    chr129588881295888904+CDS3.034287.38837K562NIPBL
    chr129588873295888761+CDS,intron-Proximal4.8769918.80346K562ZNF622
    chr129587700095877050+CDS,intron-Distal3.0887529.64718K562ZNF800
    chr129586994195869955+CDS,intron-Distal,intron-Proximal4.915336.73315K562TRA2A
    chr129588877895888846+CDS4.316069.55355K562RBM15
    chr129588793695887994+CDS,intron-Proximal4.1071339.84555K562PUM1
    chr129586806695868107+CDS,intron-Proximal3.9150530.27137K562UCHL5
    chr129587970995879756+CDS,intron-Proximal4.5738714.21310HepG2BCLAF1
    chr129589785295897908+CDS3.559438.47761HepG2BCLAF1
    chr129588788695887954+CDS3.8471732.50057K562ZNF622
    chr129587698995877041+CDS,intron-Distal,intron-Proximal7.0573871.66621K562UCHL5
    chr129587971595879758+CDS,intron-Proximal3.439245.14772K562TRA2A
    chr129590571895905773+CDS,intron-Distal3.4206313.65433K562ZNF622
    chr129587698795877057+CDS,intron-Distal,intron-Proximal3.5162417.88928HepG2AQR
    chr129587700595877057+CDS,intron-Distal,intron-Proximal5.104865.97118HepG2FXR2
    chr129588787795887992+CDS3.213764.45218HepG2ZNF800
    chr129588876995888821+CDS4.3674513.56940K562ZNF800
    chr129586991495869954+CDS,intron-Distal,intron-Proximal4.4437120.82848K562UCHL5
    chr129586807095868170+CDS,intron-Proximal3.195073.18415HepG2PRPF8
    chr129587965395879689+CDS,intron-Proximal3.5657217.51907K562ZNF800
    chr129587965395879658+CDS,intron-Proximal3.9034313.08500K562ZNF622
    chr129587965495879716+CDS,intron-Proximal3.014364.90668HepG2GRWD1
    chr129586988895869945+CDS,intron-Distal,intron-Proximal4.6240420.17423K562ZNF622
    chr129588881795888869+CDS3.3507510.93472K562ZNF622
    chr129586809095868106+CDS4.190928.25234K562ZNF622
    chr129588873195888757+CDS,intron-Proximal3.8281914.88813K562UCHL5
    chr129588783295887858+CDS4.284404.21087HepG2GRWD1
    chr129587965495879713+CDS,intron-Proximal4.9082451.63969K562UCHL5
    chr129588795395887993+CDS3.7441912.26681K562GRWD1
    chr129588876895888871+CDS3.6891818.76085HepG2BCLAF1
    chr129590571495905764+CDS,intron-Distal3.087655.90115K562GRWD1
    chr129586983995869970+CDS,intron-Distal,intron-Proximal3.0254910.31625K562GPKOW
    chr129586984695869878+CDS,intron-Distal,intron-Proximal3.9247523.76589K562UCHL5
    chr129587698895877059+CDS,intron-Distal,intron-Proximal3.100655.65359K562SRSF7
    chr129589790895897935+CDS3.876636.81385HepG2BCLAF1
    chr129587965495879658+CDS,intron-Proximal3.558569.47045K562GRWD1
    chr129588875995888823+CDS6.4726642.40439K562PUM1
    chr129587971695879756+CDS,intron-Proximal4.124048.16229HepG2GRWD1
    chr129587698995877057+CDS,intron-Distal,intron-Proximal5.2445625.06330K562TRA2A
    chr129588876195888817+CDS4.0518417.81341K562ZNF622
    chr129587971395879753+CDS,intron-Proximal3.1404312.72552K562UCHL5
    chr129587965895879704+CDS,intron-Proximal3.7787011.29876K562GRWD1
    chr129586984995869888+CDS,intron-Distal,intron-Proximal4.7606910.62290K562ZNF622
    chr129587701295877050+CDS,intron-Distal3.2963529.53081K562GRWD1
    chr129587701695877047+CDS,intron-Distal3.502506.42940HepG2GRWD1
    chr129588873295888756+CDS,intron-Proximal3.166037.06547K562GRWD1
    chr129587965495879678+CDS,intron-Proximal3.9855410.83283K562PUM1
    chr129587704795877057+CDS,intron-Distal,intron-Proximal3.492459.34297K562PUM1
    chr129588795295887992+CDS4.567329.72888HepG2GRWD1
    chr129589785495897918+CDS4.3369120.82848K562UCHL5
    chr129588783195887873+CDS,intron-Proximal3.8164011.70058K562ZNF622
    chr129588795195887994+CDS,intron-Proximal4.0660314.20559HepG2BCLAF1
    chr129588877695888881+CDS3.963308.01794HepG2HLTF
    chr129587965895879709+CDS,intron-Proximal4.5210429.24035K562ZNF622
    chr129590576795905774+CDS,intron-Distal3.987699.87150K562UCHL5
    chr129588881795888866+CDS4.4427416.42772K562UCHL5
    chr129586801795868084+CDS3.226916.90893HepG2GRWD1
    chr129586994595869954+CDS,intron-Distal3.9013611.70058K562ZNF622
    chr129587965395879729+CDS,intron-Proximal3.221129.20921K562CPSF6
    chr129589791695897937+CDS3.196305.99472K562GRWD1
    chr129587699095877016+CDS,intron-Distal,intron-Proximal3.319346.01489HepG2GRWD1
    chr129590566995905705+CDS,intron-Distal,intron-Proximal4.187849.37631HepG2BCLAF1
    chr129588882395888875+CDS5.6935923.64251K562PUM1
    chr129587965495879699+CDS,intron-Proximal4.631105.23563HepG2FXR2
    chr129588882595888901+CDS4.7109410.84390HepG2GRWD1
    chr129588787595887952+CDS5.9210711.18292K562TRA2A
    chr129590570595905769+CDS,intron-Distal4.5541013.76815HepG2BCLAF1
    chr129589791595897937+CDS3.430198.10579K562ZNF622
    chr129587970995879757+CDS,intron-Proximal4.0978118.49894K562ZNF622
    chr129588795495887994+CDS,intron-Proximal4.1992027.23244K562ZNF622
    chr129588873195888759+CDS,intron-Proximal4.4206116.59446K562PUM1
    chr129587704195877057+CDS,intron-Distal,intron-Proximal5.8608143.33206K562UCHL5
    chr129587699095877058+CDS,intron-Distal,intron-Proximal4.375907.40660HepG2TRA2A
    chr129589791895897936+CDS4.4429714.47660K562UCHL5
    chr129586801695868090+CDS3.5621725.20165K562ZNF622
    chr129587965295879705+CDS,intron-Proximal3.877267.13579HepG2AGGF1
    chr129587697995877064+CDS,intron-Distal,intron-Proximal3.2742416.91567K562GPKOW
    chr129589784995897923+CDS3.692839.16268HepG2GRWD1
    chr129586994595869954+CDS,intron-Distal3.0151417.23971K562ZNF800
    chr129588787795887993+CDS4.4727949.88078K562UCHL5
    chr129587463695874696+intron-Distal3.375223.90146K562KHSRP
    chr129589380895893902+intron-Distal3.663363.06150K562KHSRP
    chr129587427895874396+intron-Distal4.5146510.69368K562KHSRP
    chr129587947595879534+intron-Distal3.274134.95320HepG2U2AF2
    chr129587929495879349+intron-Distal3.588803.55754HepG2U2AF2
    chr129589001095890074+intron-Distal3.823163.24603K562KHSRP
    chr129589397995894054+intron-Distal4.062554.10688K562KHSRP
    chr129589431695894373+intron-Distal4.068453.59909K562EXOSC5
    chr129590464795904796+intron-Distal3.012783.11628K562KHSRP
    chr129587403895874186+intron-Distal3.318877.90229K562KHSRP
    chr129588771295887830+intron-Distal,intron-Proximal3.9775811.85698K562KHSRP
    chr129588137795881440+intron-Distal4.938305.95026HepG2U2AF2
    chr129589123095891336+intron-Distal4.791788.14619K562KHSRP
    chr129589687095896955+intron-Distal3.090073.68839K562KHSRP
    chr129587913195879193+intron-Distal4.123973.92684K562KHSRP
    chr129587442195874564+intron-Distal3.6930210.51920K562KHSRP
    chr129588765995887712+intron-Distal3.954684.07352K562KHSRP
    chr129588945095889508+intron-Distal3.584265.14864K562KHSRP
    chr129586965595869719+intron-Distal4.068534.54401K562KHSRP
    chr129586810995868201+intron-Proximal3.929357.64728K562AQR
    ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




    No autoregularoty interactions between protein METAP2 and its RNA.



    Diffrential Expression
    • 6,876 differentially expressed genes after Knockdown/Knockout METAP2 protein.  





    • 98 RBPs can affect the levels of METAP2.  







    6,876 differentially expressed genes after Knockdown/Knockout METAP2 protein :

    Only display 100 entries as example. Please click "View All" button to see all 6,876 entries.     

    Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
    C1orf112ENSG00000000460.12111.23920238.91270-1.102804.478103.15840HepG2METAP2
    CYP51A1ENSG00000001630.111202.202702704.58270-1.169707.146105.54050HepG2METAP2
    KRIT1ENSG00000001631.10351.05230521.16620-0.570102.424201.43760HepG2METAP2
    LAP3ENSG00000002549.81905.957301392.476600.452802.599101.57790HepG2METAP2
    LASP1ENSG00000002834.136855.495804960.707000.466603.104301.98790HepG2METAP2
    DBNDD1ENSG00000003249.91288.74390658.791900.968007.786606.11390HepG2METAP2
    SLC7A2ENSG00000003989.121885.786204681.63200-1.3118011.802409.77380HepG2METAP2
    ARHGAP33ENSG00000004777.14110.11540231.39050-1.071303.861302.62400HepG2METAP2
    HCCSENSG00000004961.10355.14010219.572900.693602.938401.85340HepG2METAP2
    DVL2ENSG00000004975.7445.69310659.47150-0.565302.534801.52570HepG2METAP2
    SLC25A5ENSG00000005022.51732.270602999.32390-0.792005.153503.74660HepG2METAP2
    ACSM3ENSG00000005187.7497.50620710.36340-0.513802.634501.60730HepG2METAP2
    CIAPIN1ENSG00000005194.10805.29520551.162700.546902.599501.57790HepG2METAP2
    RHBDD2ENSG00000005486.12575.72020360.818100.674003.089401.97550HepG2METAP2
    ZNF195ENSG00000005801.12627.61580325.063000.949105.914504.42300HepG2METAP2
    ITGA3ENSG00000005884.13169.3124057.478401.558506.032704.52880HepG2METAP2
    ASB4ENSG00000005981.8244.5375072.507501.753809.310407.50480HepG2METAP2
    GDE1ENSG00000006007.72295.608101240.829000.887504.707703.35660HepG2METAP2
    SPATA20ENSG00000006282.151401.78710925.049900.599603.659702.45650HepG2METAP2
    TNFRSF12AENSG00000006327.9559.00530298.124000.906805.328503.90350HepG2METAP2
    BAIAP2L1ENSG00000006453.9901.83800578.174900.641303.274902.13040HepG2METAP2
    JHDM1DENSG00000006459.61166.665301885.50240-0.692604.099702.82940HepG2METAP2
    ELAC2ENSG00000006744.14872.95360577.874600.595002.912401.83280HepG2METAP2
    ARSDENSG00000006756.11310.78690172.344800.850503.418302.25110HepG2METAP2
    ADIPOR2ENSG00000006831.91604.802002276.87530-0.504702.660801.62810HepG2METAP2
    PAX6ENSG00000007372.16119.5149028.731502.056406.560504.99730HepG2METAP2
    LUC7LENSG00000007392.12468.03440961.56350-1.038807.713106.04980HepG2METAP2
    MYLIPENSG00000007944.10236.9288094.696801.323005.970204.47290HepG2METAP2
    SPAG9ENSG00000008294.161814.125702611.74000-0.525702.957201.86710HepG2METAP2
    AASSENSG00000008311.10302.46700475.32440-0.652102.981401.88720HepG2METAP2
    PLEKHG6ENSG00000008323.1190.01880229.83870-1.352306.018304.51730HepG2METAP2
    NFIXENSG00000008441.12201.11140357.66830-0.830603.781402.55770HepG2METAP2
    ST3GAL1ENSG00000008513.10714.902801180.74170-0.723904.933303.55200HepG2METAP2
    IL32ENSG00000008517.122425.624901470.409700.722005.705804.23980HepG2METAP2
    RPS20ENSG00000008988.53617.907204901.05680-0.437902.309901.34580HepG2METAP2
    MLXIPLENSG00000009950.111080.275802159.72360-0.999407.387905.75860HepG2METAP2
    BAZ1BENSG00000009954.61500.540702267.40660-0.595603.744602.52610HepG2METAP2
    SPRTNENSG00000010072.11194.4106095.736401.021903.382602.22310HepG2METAP2
    NCAPD2ENSG00000010292.81448.726102953.10670-1.0274010.984209.02430HepG2METAP2
    IDSENSG00000010404.131158.71460641.412000.853104.477103.15780HepG2METAP2
    CD4ENSG00000010610.5191.13350104.510100.870802.782301.72780HepG2METAP2
    SCMH1ENSG00000010803.12723.117301051.07160-0.539602.809501.74880HepG2METAP2
    FYNENSG00000010810.131494.64600721.969201.049709.664407.82770HepG2METAP2
    TCEB3ENSG00000011007.81067.18660717.055800.573603.175802.04830HepG2METAP2
    LYPLA2ENSG00000011009.61343.09710871.277700.624303.429102.25980HepG2METAP2
    CLCN6ENSG00000011021.17816.366801293.74050-0.664304.693703.34440HepG2METAP2
    TSPAN9ENSG00000011105.7488.34180773.91430-0.664303.791002.56590HepG2METAP2
    MBTD1ENSG00000011258.11697.634501100.06700-0.657003.796102.57000HepG2METAP2
    PTBP1ENSG00000011304.122486.775603709.64700-0.577003.394802.23260HepG2METAP2
    PLAURENSG00000011422.7128.7316040.836001.656404.981603.59720HepG2METAP2
    ANLNENSG00000011426.6864.818702067.76460-1.2576014.1963011.98250HepG2METAP2
    BRCA1ENSG00000012048.15406.41880674.33490-0.730504.280202.98530HepG2METAP2
    EXTL3ENSG00000012232.4819.93420473.062200.793404.673903.32740HepG2METAP2
    NR1H4ENSG00000012504.9106.79410571.51330-2.4200024.9854022.12740HepG2METAP2
    PSMC4ENSG00000013275.31124.71740814.149600.466102.276901.32080HepG2METAP2
    CLDN11ENSG00000013297.6335.48930144.306401.217006.209104.68310HepG2METAP2
    MVPENSG00000013364.141351.29980573.502201.2364013.0823010.95730HepG2METAP2
    TACC3ENSG00000013810.14475.62920920.82770-0.953104.904303.52850HepG2METAP2
    GLT8D1ENSG00000016864.12724.462201092.90480-0.593203.056801.95040HepG2METAP2
    PHLDB1ENSG00000019144.12771.36510414.875200.894605.875604.38930HepG2METAP2
    CYP24A1ENSG00000019186.5665.94610384.651600.791804.811303.44870HepG2METAP2
    CD74ENSG00000019582.102058.705901330.290800.629904.037902.77620HepG2METAP2
    NCDNENSG00000020129.11410.48220166.842301.298702.755201.70530HepG2METAP2
    C8BENSG00000021852.879.68130253.80700-1.671409.334707.52790HepG2METAP2
    DERAENSG00000023697.8287.05870479.36570-0.739802.391301.40970HepG2METAP2
    ABCC2ENSG00000023839.64133.986705631.00830-0.445902.662601.62890HepG2METAP2
    DEPDC1ENSG00000024526.12165.65360486.11780-1.5531012.3332010.25350HepG2METAP2
    TOMM34ENSG00000025772.72687.42400869.833701.6273013.7043011.52300HepG2METAP2
    FASENSG00000026103.15234.79240109.560201.099604.129102.85450HepG2METAP2
    RNASET2ENSG00000026297.111676.763302727.15900-0.701704.705203.35450HepG2METAP2
    IFNGR1ENSG00000027697.82327.222201379.001300.754906.343004.80140HepG2METAP2
    BRD9ENSG00000028310.13513.15990329.976400.636902.903901.82630HepG2METAP2
    BAK1ENSG00000030110.8388.87640246.329000.658602.717201.67470HepG2METAP2
    CENPQENSG00000031691.6114.22010247.98870-1.118504.413703.10300HepG2METAP2
    ABCF2ENSG00000033050.3789.10950525.702300.585902.833401.76720HepG2METAP2
    FUT8ENSG00000033170.12748.16020312.792901.2580010.547308.61740HepG2METAP2
    UBA6ENSG00000033178.8714.772401014.29410-0.504902.299501.33830HepG2METAP2
    UHRF1ENSG00000034063.9442.84490758.62920-0.776604.342203.03980HepG2METAP2
    TMSB10ENSG00000034510.48221.693403347.342501.296308.997907.21950HepG2METAP2
    RNF19AENSG00000034677.7725.510901215.05280-0.743904.342203.03980HepG2METAP2
    SH3YL1ENSG00000035115.17360.63680568.33270-0.656202.764901.71270HepG2METAP2
    DEPDC1BENSG00000035499.8361.01920600.14090-0.733204.005702.75050HepG2METAP2
    TIMP2ENSG00000035862.82967.82530988.633501.585804.067402.80330HepG2METAP2
    RFC1ENSG00000035928.101445.922102587.49840-0.839607.277405.66020HepG2METAP2
    VCANENSG00000038427.118173.482102240.573401.8670037.6634034.34170HepG2METAP2
    CDH1ENSG00000039068.14339.88200698.24350-1.038706.441204.88840HepG2METAP2
    DNAH5ENSG00000039139.929.653802.834103.387203.115301.99650HepG2METAP2
    RAI14ENSG00000039560.91216.00890642.678900.919907.595205.94230HepG2METAP2
    SPDL1ENSG00000040275.12240.41080411.87560-0.776703.365902.20880HepG2METAP2
    PHF23ENSG00000040633.8720.34650390.138700.884605.977004.47850HepG2METAP2
    LSG1ENSG00000041802.6444.92080303.491700.551802.285601.32760HepG2METAP2
    PARP3ENSG00000041880.10492.07580292.382600.750902.768101.71510HepG2METAP2
    AIFM2ENSG00000042286.10346.27490566.49400-0.710103.181002.05220HepG2METAP2
    PHKA2ENSG00000044446.71660.542803007.87430-0.857107.696006.03360HepG2METAP2
    CPENSG00000047457.919238.8211028368.94040-0.560302.824101.76010HepG2METAP2
    MAP4ENSG00000047849.174991.444903727.577400.421102.256401.30610HepG2METAP2
    USP28ENSG00000048028.7380.67300614.73280-0.691403.511002.33030HepG2METAP2
    TSPAN17ENSG00000048140.13411.74090238.777900.786003.820102.58970HepG2METAP2
    RRM2BENSG00000048392.71225.89540754.424300.700304.729203.37690HepG2METAP2
    KITLGENSG00000049130.9414.01870108.611001.9304015.7256013.39600HepG2METAP2
    Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

    *: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
    **: "-log(0)" was displayed as "99999.99999".





    98 RBPs can affect the gene expression of METAP2 :

    Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
    METAP2ENSG00000111142.92120.954701707.058600.313102.566001.53110HepG2AATF
    METAP2ENSG00000111142.92781.460303822.79340-0.4588010.909709.69750HepG2AUH
    METAP2ENSG00000111142.91638.160402095.66490-0.355302.129901.31100HepG2BCCIP
    METAP2ENSG00000111142.91125.180701821.01480-0.694607.439206.04820HepG2BCLAF1
    METAP2ENSG00000111142.92247.439703925.84650-0.8047014.3768013.16290HepG2BOP1
    METAP2ENSG00000111142.92102.591503658.89400-0.799203.751402.60310HepG2CCAR1
    METAP2ENSG00000111142.92312.499201996.282700.212002.907802.23000HepG2CKAP4
    METAP2ENSG00000111142.91367.779801959.63820-0.518802.928902.14070HepG2CNOT7
    METAP2ENSG00000111142.92678.755703604.21780-0.428104.399403.54990HepG2CPSF6
    METAP2ENSG00000111142.92558.830303101.17410-0.277305.243604.26830HepG2DAZAP1
    METAP2ENSG00000111142.92094.816401846.643300.181802.105001.37010HepG2DDX19B
    METAP2ENSG00000111142.92216.841601843.209100.266202.251701.43800HepG2DDX24
    METAP2ENSG00000111142.92557.394803663.69060-0.518602.844102.21020HepG2DDX3X
    METAP2ENSG00000111142.91575.113002060.45000-0.387502.498101.75850HepG2DDX55
    METAP2ENSG00000111142.91676.186703146.41110-0.908507.040606.09350HepG2DDX6
    METAP2ENSG00000111142.91250.997201784.39650-0.512408.567607.38520HepG2DNAJC21
    METAP2ENSG00000111142.91351.655701768.59820-0.387907.303906.31370HepG2DNAJC2
    METAP2ENSG00000111142.91581.228701990.88600-0.332402.377901.52080HepG2EEF2
    METAP2ENSG00000111142.91756.166703025.49040-0.784705.566504.74290HepG2EIF2S1
    METAP2ENSG00000111142.91663.074103343.89460-1.007707.709506.64430HepG2EIF4A3
    METAP2ENSG00000111142.92212.972803255.04050-0.556703.559602.78390HepG2EIF4B
    METAP2ENSG00000111142.93539.467103059.575300.210102.662401.83800HepG2EIF4G1
    METAP2ENSG00000111142.92202.262502930.86360-0.412304.122403.13870HepG2EIF4G2
    METAP2ENSG00000111142.92871.545004389.06610-0.6121017.9918016.67960HepG2ETF1
    METAP2ENSG00000111142.91955.919003078.13020-0.654203.673402.79470HepG2FIP1L1
    METAP2ENSG00000111142.92549.011603372.72370-0.404002.135101.52370HepG2FXR1
    METAP2ENSG00000111142.91577.851103129.28800-0.987907.925206.82940HepG2G3BP1
    METAP2ENSG00000111142.91020.692101439.03570-0.495604.507803.35670HepG2GEMIN5
    METAP2ENSG00000111142.91399.406002039.19570-0.543205.034703.65510HepG2GNB2L1
    METAP2ENSG00000111142.93065.757104085.87230-0.414403.431302.72450HepG2GPKOW
    METAP2ENSG00000111142.9950.487701801.49100-0.9225016.8729015.50010HepG2HNRNPA1
    METAP2ENSG00000111142.92392.137402850.11080-0.252703.174202.18250HepG2HNRNPA2B1
    METAP2ENSG00000111142.91069.272202003.81190-0.9061016.5010014.94710HepG2HNRNPC
    METAP2ENSG00000111142.91934.237402615.87250-0.435506.978305.90730HepG2HNRNPF
    METAP2ENSG00000111142.92267.758903899.20410-0.781907.857106.85700HepG2HNRNPLL
    METAP2ENSG00000111142.91653.492101990.56490-0.267703.474102.80320HepG2HNRNPU
    METAP2ENSG00000111142.91740.334102575.91250-0.565708.843807.62090HepG2IGF2BP1
    METAP2ENSG00000111142.91891.447703181.06350-0.750005.240704.33760HepG2IGF2BP2
    METAP2ENSG00000111142.92192.290903373.89620-0.622004.324703.50760HepG2MAGOH
    METAP2ENSG00000111142.9404.472601691.53820-2.0642030.5763027.55570HepG2METAP2
    METAP2ENSG00000111142.91755.736602492.36810-0.505402.691001.89310HepG2MSI2
    METAP2ENSG00000111142.91866.524103473.03470-0.895806.648205.68610HepG2NCBP2
    METAP2ENSG00000111142.91890.627803075.12270-0.7018016.1304014.37300HepG2NOL12
    METAP2ENSG00000111142.92026.762003093.64780-0.610103.847703.00760HepG2PABPC4
    METAP2ENSG00000111142.92306.260603135.58460-0.443209.624608.60320HepG2PCBP1
    METAP2ENSG00000111142.92807.366202367.918800.245503.169302.34720HepG2PRPF4
    METAP2ENSG00000111142.91119.897301589.60330-0.505304.277903.29780HepG2PRPF8
    METAP2ENSG00000111142.92106.585503190.56670-0.5989016.1487015.03870HepG2PTBP1
    METAP2ENSG00000111142.92724.460103116.18980-0.193802.829502.23140HepG2PUM1
    METAP2ENSG00000111142.91729.622703113.89570-0.8483021.4511019.69690HepG2PUM2
    METAP2ENSG00000111142.91790.313602033.72260-0.183901.989201.44810HepG2PUS1
    METAP2ENSG00000111142.92116.083103455.47920-0.7075017.3571015.98600HepG2QKI
    METAP2ENSG00000111142.92385.490803136.06320-0.394704.823003.95500HepG2RBM25
    METAP2ENSG00000111142.92450.115803550.80090-0.5353013.6896012.65620HepG2NELFE
    METAP2ENSG00000111142.92032.258202817.56250-0.471405.347204.43970HepG2RPLP0
    METAP2ENSG00000111142.91738.269402221.64800-0.354002.847102.03610HepG2RPS2
    METAP2ENSG00000111142.91401.578601966.83250-0.488803.284502.41380HepG2RPS3A
    METAP2ENSG00000111142.91259.470401772.69420-0.4931010.257109.13800HepG2SAFB2
    METAP2ENSG00000111142.92445.004503321.80580-0.442109.725608.71620HepG2SF3B4
    METAP2ENSG00000111142.92391.673502814.74420-0.235003.615802.83130HepG2SLBP
    METAP2ENSG00000111142.94015.676103467.240400.211803.006302.51820HepG2SRSF1
    METAP2ENSG00000111142.92563.934902898.41140-0.176901.881601.35180HepG2SRSF5
    METAP2ENSG00000111142.91727.817902569.92210-0.5728012.7828011.47500HepG2SRSF7
    METAP2ENSG00000111142.92037.123102820.77980-0.4696011.1048010.12900HepG2SRSF9
    METAP2ENSG00000111142.91474.375602079.47080-0.496102.369201.49460HepG2SUPT6H
    METAP2ENSG00000111142.91275.008303799.95850-1.5755035.6611033.62640HepG2TARDBP
    METAP2ENSG00000111142.92210.941402863.63280-0.373204.526003.46390HepG2TIA1
    METAP2ENSG00000111142.91360.367601934.25740-0.507807.482306.73340HepG2TIAL1
    METAP2ENSG00000111142.91480.972001951.49280-0.398006.747405.93390HepG2TRIM56
    METAP2ENSG00000111142.92399.061602867.90440-0.257502.264401.47980HepG2TUFM
    METAP2ENSG00000111142.91524.319402211.08280-0.5366012.7240011.42950HepG2UPF1
    METAP2ENSG00000111142.91822.922102272.69980-0.318204.442603.15110HepG2UTP18
    METAP2ENSG00000111142.91641.630102134.71680-0.378906.604405.74600HepG2UTP3
    METAP2ENSG00000111142.91252.713201761.64440-0.491903.209602.01850HepG2XPO5
    METAP2ENSG00000111142.91735.997902336.85900-0.428809.732308.60110HepG2ZC3H8
    METAP2ENSG00000111142.91583.764502431.77080-0.6186020.6234019.47090HepG2ZNF622
    METAP2ENSG00000111142.94824.572606827.28130-0.500906.983706.12090K562AQR
    METAP2ENSG00000111142.92892.345203768.01580-0.381608.326706.62870K562BCLAF1
    METAP2ENSG00000111142.94549.891506131.37260-0.430406.835304.96630K562CCDC124
    METAP2ENSG00000111142.95108.8073010551.06730-1.046303.470702.25730K562CNOT7
    METAP2ENSG00000111142.95017.787506495.74970-0.372407.314705.48640K562CPEB4
    METAP2ENSG00000111142.94442.640307132.15630-0.682902.138201.44000K562CPSF6
    METAP2ENSG00000111142.92353.965502858.60170-0.280203.450202.24920K562CSTF2
    METAP2ENSG00000111142.93312.653604039.02420-0.286004.601603.01740K562DDX21
    METAP2ENSG00000111142.98355.739806721.600300.313906.454905.51770K562DDX47
    METAP2ENSG00000111142.96755.156605744.812400.233603.100902.16600K562DKC1
    METAP2ENSG00000111142.93573.177305227.73720-0.5490013.8287012.40600K562EIF2S2
    METAP2ENSG00000111142.94167.458703562.884800.226002.326701.59430K562EIF3G
    METAP2ENSG00000111142.96940.691408141.26670-0.230202.968901.99770K562EIF4G2
    METAP2ENSG00000111142.94063.777503031.722100.422608.391807.40880K562FXR1
    METAP2ENSG00000111142.94647.359303296.338300.495403.823202.96200K562G3BP2
    METAP2ENSG00000111142.93746.855004588.90780-0.292503.999402.63500K562GLRX3
    METAP2ENSG00000111142.94867.370406966.69320-0.517308.614507.26260K562GRSF1
    METAP2ENSG00000111142.93349.619204349.23640-0.376804.845403.44150K562HNRNPA1
    METAP2ENSG00000111142.91541.284603275.15850-1.087405.904205.06390K562HNRNPC
    METAP2ENSG00000111142.94979.138206074.47240-0.286902.951101.85640K562HNRNPL
    METAP2ENSG00000111142.93543.818404363.45470-0.300202.936702.07060K562MAGOH
    METAP2ENSG00000111142.91785.198606647.11060-1.896607.749906.24910K562METAP2
    METAP2ENSG00000111142.92884.523304824.63740-0.7421030.4019028.19510K562MTPAP
    METAP2ENSG00000111142.93866.956305360.61000-0.4712021.0082019.23470K562NSUN2
    METAP2ENSG00000111142.93899.133903011.554100.372503.756902.88270K562PRPF8
    METAP2ENSG00000111142.96930.453609257.36610-0.417709.105707.34250K562PUM2
    METAP2ENSG00000111142.93847.437305289.54710-0.4592010.056808.57210K562SF3A3
    METAP2ENSG00000111142.94354.778205419.25460-0.315507.854606.37050K562SRPK2
    METAP2ENSG00000111142.93007.586003604.71050-0.261303.749802.37830K562SRSF7
    METAP2ENSG00000111142.92279.129902916.42980-0.355702.469001.51500K562SUPV3L1
    METAP2ENSG00000111142.94626.972403396.151800.446107.222705.88070K562SYNCRIP
    METAP2ENSG00000111142.93377.169304206.15350-0.316702.637901.94510K562TARDBP
    METAP2ENSG00000111142.93996.652503301.055200.275803.073402.22670K562U2AF2
    METAP2ENSG00000111142.94034.646605683.96810-0.4945015.1462013.62160K562UPF1
    METAP2ENSG00000111142.94397.607805787.38190-0.396203.604802.22560K562UTP3
    METAP2ENSG00000111142.93034.904204863.59260-0.6804013.8664011.86040K562WDR3
    METAP2ENSG00000111142.93376.100205057.56780-0.5831021.6645019.64500K562WDR43
    METAP2ENSG00000111142.95599.582807691.46180-0.457906.245604.86340K562ZC3H8
    Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

    *: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
    **: "-log(0)" was displayed as "99999.99999".





    247 alternative splicing events after Knockdown/Knockout METAP2 protein :

    Only display 100 entries as example. Please click "View All" button to see all 247 entries.     

    Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
    SESNRNP70ENSG00000104852.10chr19+4960537049606844496046464960472849607890496079920.217000.000000.00000includedK562METAP2
    SELUC7L3ENSG00000108848.11chr17+4882865748828736488281074882821348829560488299460.442000.000380.07546includedK562METAP2
    SEUSP54ENSG00000166348.13chr10-7529435775294528752904617529059375296026752961950.479000.000420.07930includedK562METAP2
    SEGOLGA8AENSG00000175265.13chr15-3471809434718223346997243469993634720815347211260.052000.000090.02726includedK562METAP2
    SENSUN6ENSG00000241058.1chr10-1893249718932569189314041893148418937418189375740.091000.000010.00477includedK562METAP2
    SEKIF23ENSG00000137807.9chr15+6973310669733418697326466973282669737128697373800.104000.000400.07843includedK562METAP2
    SENUSAP1ENSG00000137804.8chr15+4164231041642398416412954164143941643185416433270.052000.000000.00000includedK562METAP2
    SEMKI67ENSG00000148773.8chr10-1299142031299142711299116901299118661299147541299148000.209000.000500.08961includedK562METAP2
    SEMBNL1ENSG00000152601.13chr3+1520171931520174201519621091519622291521327291521328980.335000.000000.00006includedK562METAP2
    SEALDOAENSG00000149925.12chr16+3007719630077248300757443007582630078554300786870.127000.000000.00003includedK562METAP2
    SEPSMD6ENSG00000163636.6chr3-6400841464008477640079936400819964008950640091320.060000.000010.00452includedK562METAP2
    SESREK1ENSG00000153914.11chr5+6545189265454760654492906544942465455046654551620.263000.000000.00000includedK562METAP2
    SERNASEK-C17orf49ENSG00000161939.14chr17+6916637691683569159536916080691698469170610.069000.000070.02253includedK562METAP2
    SENDUFV3ENSG00000160194.13chr21+4432329144324386443170364431715744328973443292150.126000.000030.01218includedK562METAP2
    SECHMP3ENSG00000115561.10chr2-8676823986768487867563408675652086769374867694350.107000.000270.06187includedK562METAP2
    SEWNK1ENSG00000060237.12chr12+9770319782709712489714369873779875270.136000.000460.08468includedK562METAP2
    SEGPBP1L1ENSG00000159592.6chr1-4615124746151292461262204612689746153654461537850.273000.000290.06442includedK562METAP2
    SEPICALMENSG00000073921.13chr11-8568575085685855856698568567010385692171856922710.071000.000190.04956includedK562METAP2
    SEDCAF6ENSG00000143164.11chr1+1679922251679922851679737701679740311680076081680077260.158000.000270.06187includedK562METAP2
    SEOGTENSG00000147162.9chrX+7076619370766346707644167076448570767756707678730.195000.000310.06634includedK562METAP2
    SEOGTENSG00000147162.9chrX+7077503970775235707743627077444270775803707759440.138000.000010.00357includedK562METAP2
    SEMTRRENSG00000124275.10chr5+7890389789052578892077889388789148478915270.080000.000430.08024includedK562METAP2
    SEANKHD1ENSG00000131503.16chr5+1399149461399150021399092141399093811399169221399171740.202000.000370.07364includedK562METAP2
    SECOCHENSG00000100473.11chr14+3135411531354247313537583135386231354599313548260.092000.000070.02330includedK562METAP2
    SENSFL1CENSG00000088833.13chr20-1426639142679414263101426475143313714332750.101000.000010.00491includedK562METAP2
    SEFNBP4ENSG00000109920.8chr11-4774728847747388477460234774633047752925477531130.088000.000000.00001includedK562METAP2
    SEHMGN1ENSG00000205581.6chr21-4071775540717884407170644071720040719304407194090.168000.000420.08024includedK562METAP2
    SELPGAT1ENSG00000123684.8chr1-2119609732119610692119565702119568442119664132119665320.117000.000020.00918includedK562METAP2
    SEANXA2ENSG00000182718.12chr15-6068945660689537606782266067828560690141606901720.192000.000110.03333includedK562METAP2
    SEGDAENSG00000119125.12chr9+7477695274777167747295107472974974810415748105040.177000.000230.05636includedK562METAP2
    SECCBL2ENSG00000137944.12chr1-8945393489454034894350918943515089458267894586040.393000.000160.04454includedK562METAP2
    SETMEM168ENSG00000146802.8chr7-1124285081124285991124237521124250081124302141124304480.289000.000390.07613includedK562METAP2
    SEMITD1ENSG00000158411.6chr2-9978987699789965997879729978810999790377997904700.132000.000250.06010includedK562METAP2
    SECD47ENSG00000196776.10chr3-1077707851077708171077621451077661391077763231077764160.279000.000010.00452includedK562METAP2
    SEFAM208BENSG00000108021.15chr10+5762222576236057596215759713576250657626310.226000.000100.03134includedK562METAP2
    SESMG5ENSG00000198952.7chr1-1562433541562434391562431511562432411562443871562444770.058000.000250.05989includedK562METAP2
    SERP11-669N7.2ENSG00000249196.2chr12+1295959641295960601295955371295956841295976091295978380.099000.000460.08442includedK562METAP2
    SESLMO2ENSG00000101166.11chr20-5761224557612335576117445761181557613520576136890.069000.000220.05449includedK562METAP2
    SEGS1-179L18.1ENSG00000205628.2chr7-5384784953847923538476385384773153879200538796240.343000.000490.08831includedK562METAP2
    SEHNRNPDLENSG00000152795.13chr4-8334671583346820833457818334603683347189833473030.074000.000120.03603includedK562METAP2
    SECREBZFENSG00000137504.9chr11-8537422285374337853729968537350185374567853746450.150000.000080.02705includedK562METAP2
    SERNPC3ENSG00000185946.11chr1+1040795371040796721040787471040788161040799631040801060.063000.000020.00907includedK562METAP2
    SEPMPCBENSG00000105819.9chr7+1029480421029481551029448571029449371029493981029495420.178000.000180.04697includedK562METAP2
    SENFATC2IPENSG00000176953.6chr16+2896588528966042289634522896352528967298289673790.105000.000250.06036includedK562METAP2
    SENLRP1ENSG00000091592.11chr17-5418792541883754047045405192542106554212070.224000.000130.03807includedK562METAP2
    SEARPC4-TTLL3ENSG00000250151.5chr3+9870183987025998686809868924987064398710790.130000.000270.06187includedK562METAP2
    SENUPL2ENSG00000136243.12chr7+2323679123236866232362982323638523239076232391610.185000.000020.00740includedK562METAP2
    SECACYBPENSG00000116161.13chr1+1749692241749693311749685701749688251749737491749738060.069000.000420.07930includedK562METAP2
    SEBCAP29ENSG00000075790.6chr7+1072540981072541771072537761072538771072587721072591090.305000.000210.05380includedK562METAP2
    SETFPIENSG00000003436.10chr2-1883940901883942121883683741883684971884189261884190760.066000.000180.04818includedK562METAP2
    SEGFI1BENSG00000165702.8chr9+1358644471358645851358635831358638551358651281358652940.081000.000280.06361includedK562METAP2
    SERAI14ENSG00000039560.9chr5+3481367834813765348122843481231334814687348147740.180000.000150.04299includedK562METAP2
    SEUQCRHENSG00000173660.7chr1+4677556846775716467747724677479946775826467759880.120000.000000.00275includedK562METAP2
    SESPRYD7ENSG00000123178.10chr13-5050515350505270505020575050222150510265505104760.171000.000110.03487includedK562METAP2
    SEGLT8D1ENSG00000016864.12chr3-5273873952738968527344605273451252739462527397800.434000.000290.06442includedK562METAP2
    SESRP9ENSG00000143742.8chr1+2259745632259746872259710012259710702259769412259781680.072000.000000.00003includedK562METAP2
    SEGAS5ENSG00000234741.3chr1-1738346471738346851738343661738344201738358981738359340.060000.000000.00001includedK562METAP2
    SEHMGN3ENSG00000118418.10chr6-7991177279911872799109617991144379911992799121060.154000.000000.00000includedK562METAP2
    SEARGLU1ENSG00000134884.9chr13-1072099061072099641072093951072094791072117791072120050.135000.000000.00001includedK562METAP2
    SECLASP1ENSG00000074054.13chr2-1221451631221452301221446971221448041221453381221456520.093000.000440.08186includedK562METAP2
    SERBM39ENSG00000131051.16chr20-3432844634328519343268893432693934328745343288090.123000.000000.00000includedK562METAP2
    SEPSMA1ENSG00000129084.13chr11-1454141814541574145405421454058714541842145419910.077000.000130.03890includedK562METAP2
    SETXNL4AENSG00000141759.10chr18-7773759777737701777328747773385677748239777485930.115000.000000.00006includedK562METAP2
    SEIP6K2ENSG00000068745.10chr3-4875282148752952487314834873285148754589487546490.221000.000320.06652includedK562METAP2
    SEZMYND8ENSG00000101040.15chr20-4584128645841370458394054583954245848908458489750.166000.000000.00015includedK562METAP2
    SERPL17ENSG00000265681.2chr18-4701810547018203470178864701795447018644470187690.225000.000000.00001includedK562METAP2
    SEC1orf63ENSG00000117616.13chr1-2557094425570989255700402557071525571640255717920.401000.000000.00284includedK562METAP2
    SESRRM1ENSG00000133226.12chr1+2498967324989715249891502498929524993305249934160.115000.000030.01124includedK562METAP2
    SESRRM1ENSG00000133226.12chr1+2497356924973699249731572497328024975349249755200.263000.000000.00000includedK562METAP2
    SEOSBPL6ENSG00000079156.12chr2+1792043981792044911792037171792038211792139501792141160.161000.000000.00000includedK562METAP2
    SEFKBP15ENSG00000119321.4chr9-1159737561159738721159694911159695761159834701159835980.087000.000300.06612includedK562METAP2
    SEFAM192AENSG00000172775.12chr16-5721241357212764572076395720778157219732572199510.177000.000000.00222includedK562METAP2
    SEAC034193.5ENSG00000180385.4chr3+1003039510030431100285761002894810044400100444490.443000.000320.06717includedK562METAP2
    SEMICAL1ENSG00000135596.13chr6-1097732011097733221097728021097729031097734481097736040.403000.000070.02330includedK562METAP2
    SEPTPN12ENSG00000127947.11chr7+7721074377210820772003947720050377214859772148980.116000.000000.00175includedK562METAP2
    SEZNF512ENSG00000243943.5chr2+2783968527839812278391282783919127840339278404380.090000.000320.06652includedK562METAP2
    SEPARLENSG00000175193.8chr3-1835515111835516131835512791835513771835583571835584280.234000.000000.00081includedK562METAP2
    SECNDP2ENSG00000133313.10chr18+7216474372164961721636067216366672167171721672680.282000.000010.00357includedK562METAP2
    SEMAXENSG00000125952.14chr14-6554406165544146655431796554338165544630655447540.094000.000000.00020includedK562METAP2
    SETIAL1ENSG00000151923.13chr10-1213363581213364171213361221213362621213365911213367260.128000.000000.00001includedK562METAP2
    SERSRC2ENSG00000111011.13chr12-1230050501230051281230034761230035761230059311230059750.102000.000000.00030includedK562METAP2
    SESTRBPENSG00000165209.14chr9-1259018071259019661258986591258987941259091331259093330.055000.000370.07364includedK562METAP2
    SERPS24ENSG00000138326.14chr10+7979996179799983797969517979706279800372798004550.095000.000000.00006includedK562METAP2
    SEC1orf86ENSG00000162585.12chr1-212428321244142121151212122021250772125349-0.154000.000160.04556excludedK562METAP2
    SERAB5CENSG00000108774.10chr17-402897794028989640282354402826084030691040307022-0.069000.000010.00316excludedK562METAP2
    SESPG7ENSG00000197912.9chr16+896155768961574489614410896145218961690189617017-0.106000.000180.04697excludedK562METAP2
    SETTLL3ENSG00000214021.11chr3+985775798578869854931985502998622299862425-0.338000.000040.01407excludedK562METAP2
    SEFAM193BENSG00000146067.11chr5-176950159176950266176948974176949072176950957176951033-0.176000.000430.08035excludedK562METAP2
    SENAE1ENSG00000159593.10chr16-668618376686198066860579668606836686474966864879-0.065000.000310.06622excludedK562METAP2
    SEEIF4HENSG00000106682.10chr7+736045767360463673604151736042487360907073609208-0.052000.000030.01170excludedK562METAP2
    SECTTNENSG00000085733.11chr11+702675757026768670266505702666167026904570269101-0.155000.000050.01748excludedK562METAP2
    SEPICALMENSG00000073921.13chr11-856891128568913685687665856877258569217185692271-0.255000.000000.00000excludedK562METAP2
    SEDCAF6ENSG00000143164.11chr1+167985018167985189167973770167974031167992225167992285-0.242000.000020.00874excludedK562METAP2
    SEEGFL7ENSG00000172889.11chr9+139564057139564173139563008139563125139564365139564461-0.149000.000010.00642excludedK562METAP2
    SEARID1BENSG00000049618.17chr6+157192747157192786157150360157150555157222509157222659-0.060000.000380.07568excludedK562METAP2
    SEMACF1ENSG00000127603.19chr1+399465913994670239945469399456813995027239950402-0.131000.000020.00918excludedK562METAP2
    SESTAG2ENSG00000101972.14chrX+123155216123155281123095587123095706123156380123156521-0.145000.000030.01107excludedK562METAP2
    SEUPF3BENSG00000125351.6chrX-118974556118974647118972228118972490118975038118975245-0.111000.000180.04697excludedK562METAP2
    SEEPB41ENSG00000159023.14chr1+293869332938699629379615293798242939149329391670-0.121000.000010.00414excludedK562METAP2
    SETBC1D23ENSG00000036054.8chr3+100030676100030721100029246100029386100034942100035031-0.164000.000410.07930excludedK562METAP2





    12 RBPs can affect the splicing of METAP2 :

    Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
    SEMETAP2ENSG00000111142.9chr12+958797239587975795876953958770569588783195887883-0.086000.000020.00037excludedK562AQR
    SEMETAP2ENSG00000111142.9chr12+958897799588988595888732958889149589784095897937-0.058000.000000.00009excludedK562AQR
    A3SSMETAP2ENSG00000111142.9chr12+958796549587975795879723958797579587699095877056-0.184000.000000.00001shorterK562SUPV3L1
    A3SSMETAP2ENSG00000111142.9chr12+9586984695869954958699189586995495867927958681060.116000.000000.00004longerHepG2U2AF2
    A3SSMETAP2ENSG00000111142.9chr12+9586984695869954958699189586995495867927958681060.169000.000000.00000longerK562DROSHA
    A3SSMETAP2ENSG00000111142.9chr12+9586984695869954958699189586995495867927958681060.143000.000000.00167longerK562HNRNPUL1
    A3SSMETAP2ENSG00000111142.9chr12+9586984695869954958699189586995495867927958681060.119000.000070.04414longerK562SBDS
    A3SSMETAP2ENSG00000111142.9chr12+9589781995897937958978409589793795889779958898740.052000.000000.00000longerK562AQR
    A3SSMETAP2ENSG00000111142.9chr12+9586981695869954958699189586995495867927958681060.205000.000000.00001longerK562AQR
    A3SSMETAP2ENSG00000111142.9chr12+9586984695869954958699189586995495867927958681060.122000.000050.06251longerK562LARP4
    A3SSMETAP2ENSG00000111142.9chr12+958897799588987495889842958898749588873295888914-0.074000.000340.01884shorterK562U2AF1
    MXEMETAP2ENSG00000111142.9chr12+95876990958770569587965495879757958698499586995495887831958879930.126000.000110.006281includedK562UCHL5
    MXEMETAP2ENSG00000111142.9chr12+9587699095877056958796549587975795869849958699549588783195887993-0.063000.000000.000132includedK562DROSHA
    MXEMETAP2ENSG00000111142.9chr12+95876990958770569587965495879757958698499586995495887831958879930.100000.001920.052381includedK562XRN2
    MXEMETAP2ENSG00000111142.9chr12+9587699095877056958978409589793795869846958699549590567095905774-0.089000.000120.009452includedK562SF3B1
    MXEMETAP2ENSG00000111142.9chr12+95876990958770569587965495879757958698499586995495887831958879930.076000.001740.056131includedK562LIN28B
    MXEMETAP2ENSG00000111142.9chr12+95889657958897799588984295889874958887329588891495897840958979370.058000.000010.000101includedK562AQR
    MXEMETAP2ENSG00000111142.9chr12+9587699095877056958796549587975795869849958699549588783195887993-0.053000.000030.002062includedK562HNRNPUL1

    *: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
    **: "-log(0)" was displayed as "99999.99999".





    No autoregularoty alternative splicing events between protein METAP2 and its RNA.