MTHFR

General Information

Gene Name       : MTHFR
Gene ID             : ENSG00000177000.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: MTHFR)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878MTHFRENSG00000177000.123.186.134.66ENCSR000AEF
HepG2MTHFRENSG00000177000.122.451.912.18ENCSR985KAT
K562MTHFRENSG00000177000.1256.8342.0849.45ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for MTHFR is not avaliable on ENCORE database.



Proteins bound to RNA
  • MTHFR RNA is bound by 27 proteins.  







eCLIP assay for MTHFR is not avaliable on ENCORE database.





27 proteins are bound to MTHFR RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr11184967011849731-3'-UTR,intron-Distal4.419987.08557K562LIN28B
chr11184924411849319-3'-UTR,intron-Distal6.9412724.77072K562AKAP1
chr11186341111863459-3'-UTR,intron-Distal,intron-Proximal3.679315.35619K562AQR
chr11184953011849626-3'-UTR,intron-Distal5.0071750.82816K562UPF1
chr11184964711849718-3'-UTR,intron-Distal5.9654364.07373K562UPF1
chr11184946711849515-3'-UTR,intron-Distal3.4184023.73717K562UPF1
chr11184917811849244-3'-UTR,intron-Distal6.3682229.29684K562AKAP1
chr11184975311849816-3'-UTR,intron-Distal5.5209321.41826K562LIN28B
chr11184993111849979-3'-UTR,intron-Distal3.8194915.08403K562UPF1
chr11184839711848499-3'-UTR,intron-Distal5.1741450.82269K562UPF1
chr11184911511849148-3'-UTR,intron-Distal4.2284417.28969K562UPF1
chr11184904111849093-3'-UTR,intron-Distal4.6416923.49339K562UPF1
chr11184805311848064-3'-UTR,intron-Distal4.1735411.58326K562UPF1
chr11184778211847879-3'-UTR,intron-Distal3.088635.48666K562METAP2
chr11184924311849337-3'-UTR,intron-Distal4.8753342.79899K562UPF1
chr11186361311863816-3'-UTR,5'-UTR,intron-Distal,intron-Proximal3.997836.45177K562HNRNPK
chr11184972511849773-3'-UTR,intron-Distal4.8413433.35322K562UPF1
chr11186333711863376-3'-UTR,intron-Distal,intron-Proximal3.864373.05875K562RBM15
chr11184994711849961-3'-UTR,intron-Distal4.312114.81596K562AKAP1
chr11184997911850109-3'-UTR,intron-Distal4.6747349.04680K562UPF1
chr11184676311846799-3'-UTR,intron-Distal4.8479617.08773K562UPF1
chr11186319211863251-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.718895.58962K562RBM15
chr11184918211849243-3'-UTR,intron-Distal5.7775850.63816K562UPF1
chr11184976611849906-3'-UTR,intron-Distal3.4960420.85711K562AKAP1
chr11184937911849425-3'-UTR,intron-Distal5.5405415.96405K562AKAP1
chr11184982111849893-3'-UTR,intron-Distal4.610164.14433K562ZNF800
chr11184834911848397-3'-UTR,intron-Distal,intron-Proximal4.5453719.02819K562UPF1
chr11184887411848910-3'-UTR,intron-Distal5.0260321.44569K562UPF1
chr11185043411850503-3'-UTR,intron-Distal3.875244.22460K562RBM15
chr11184986111849914-3'-UTR,intron-Distal4.0912041.71611K562UPF1
chr11185001511850055-3'-UTR,intron-Distal3.618168.05153K562AKAP1
chr11184698311847005-3'-UTR,intron-Distal6.4490518.93283K562UPF1
chr11184776711847835-3'-UTR,intron-Distal4.4078230.04779K562UPF1
chr11184852511848567-3'-UTR,intron-Distal5.2946025.80437K562UPF1
chr11184686211846934-3'-UTR,intron-Distal5.0140730.19754K562UPF1
chr11184787311847891-3'-UTR,intron-Distal6.1338216.48629K562UPF1
chr11184966011849703-3'-UTR,intron-Distal3.079673.95191K562METAP2
chr11184714611847233-3'-UTR,intron-Distal4.6113635.26856K562UPF1
chr11184977311849861-3'-UTR,intron-Distal4.1371457.76500K562UPF1
chr11184935011849401-3'-UTR,intron-Distal4.8929426.99110K562UPF1
chr11185021711850237-3'-UTR,intron-Distal6.3248618.45981K562UPF1
chr11185046611850496-3'-UTR,intron-Distal4.0539115.28416K562UPF1
chr11184776411847841-3'-UTR,intron-Distal3.5249513.84854K562AKAP1
chr11184966211849700-3'-UTR,intron-Distal3.576726.59901K562AKAP1
chr11185035211850434-3'-UTR,intron-Distal5.9338043.54384K562UPF1
chr11184918211849227-3'-UTR,intron-Distal3.524114.10368K562AKAP8L
chr11184752911847584-3'-UTR,intron-Distal3.244753.09251K562METAP2
chr11184714611847194-3'-UTR,intron-Distal3.842588.49190K562AKAP1
chr11184945811849499-3'-UTR,intron-Distal3.5153713.03669K562AKAP1
chr11186578611865859-5'-UTR,intron-Distal3.956116.04229K562RBM15
chr11186563911865725-5'-UTR,intron-Distal3.303596.86059K562RBM15
chr11186591011865991-5'-UTR,intron-Distal4.477994.26442K562DDX3X
chr11186548011865563-5'-UTR,intron-Distal,intron-Proximal3.480146.87198K562RBM15
chr11185639511856513-CDS,intron-Distal,intron-Proximal3.267278.88810K562BUD13
chr11186293411863020-CDS,intron-Distal,intron-Proximal3.5263010.33108K562UCHL5
chr11186139011861442-CDS,intron-Distal3.643724.14411K562METAP2
chr11185645011856508-CDS,intron-Distal,intron-Proximal3.028995.01255K562XRN2
chr11186018411860293-CDS,intron-Distal,intron-Proximal4.2898332.80413K562EFTUD2
chr11185413711854194-CDS,intron-Distal,intron-Proximal3.4651416.01425K562SF3B4
chr11185644111856497-CDS,intron-Distal,intron-Proximal5.8291874.53328K562SF3B4
chr11186293411863001-CDS,intron-Distal,intron-Proximal3.297643.34848HepG2PPIG
chr11185459211854619-CDS,intron-Distal,intron-Proximal6.3254923.92744K562AQR
chr11185091011850987-CDS,intron-Distal3.7928016.63739K562EIF4G2
chr11186018011860282-CDS,intron-Distal,intron-Proximal3.242849.01163K562AQR
chr11185629411856383-CDS,intron-Distal5.4061221.53778K562RBM15
chr11186036111860386-CDS,intron-Distal,intron-Proximal3.234824.83230K562AQR
chr11185134911851383-CDS,intron-Distal3.551107.18470K562YBX3
chr11185090911850995-CDS,intron-Distal3.133599.64855K562BUD13
chr11185475411854806-CDS,intron-Distal,intron-Proximal3.259665.33133K562BUD13
chr11185489511854953-CDS,intron-Distal,intron-Proximal3.8546814.76988K562AQR
chr11185090411850997-CDS,intron-Distal6.0388913.42527K562TARDBP
chr11185398111854032-CDS,intron-Distal3.545205.53855K562YBX3
chr11185242711852527-CDS,intron-Distal,intron-Proximal4.607258.25856K562SF3B4
chr11185442011854484-CDS,intron-Distal3.618095.84375K562RBFOX2
chr11185455111854624-CDS,intron-Distal,intron-Proximal4.478879.94489K562BUD13
chr11185642711856461-CDS,intron-Distal,intron-Proximal3.056404.04446K562SMNDC1
chr11186036111860402-CDS,intron-Distal,intron-Proximal4.9064323.37935K562SF3B4
chr11185512111855172-CDS,intron-Distal,intron-Proximal3.235134.59873K562UCHL5
chr11186018611860288-CDS,intron-Distal,intron-Proximal3.527126.58330K562SMNDC1
chr11185411511854156-CDS,intron-Distal,intron-Proximal3.8311511.12628K562AQR
chr11185537711855421-CDS,intron-Distal,intron-Proximal3.6989615.33968K562AQR
chr11185488211854943-CDS,intron-Distal,intron-Proximal3.064045.66620K562RBFOX2
chr11186125911861315-CDS,intron-Distal,intron-Proximal3.275606.03548K562RBM15
chr11185118911851272-CDS,intron-Distal,intron-Proximal3.739256.26935K562DDX24
chr11186037511860434-CDS,intron-Distal,intron-Proximal3.399243.23253K562SMNDC1
chr11186303011863083-CDS,intron-Distal,intron-Proximal3.378834.98411K562RBM15
chr11185627611856294-CDS,intron-Distal3.786318.99990K562RBM15
chr11186022111860338-CDS,intron-Distal,intron-Proximal4.267184.38106HepG2PPIG
chr11185619111856267-CDS,intron-Distal,intron-Proximal4.4928628.57710K562AQR
chr11186116011861261-CDS,intron-Distal,intron-Proximal3.5476315.25611K562AQR
chr11186021211860286-CDS,intron-Distal,intron-Proximal3.419634.68262K562RBM15
chr11185446811854560-CDS,intron-Distal3.127835.60102K562GRWD1
chr11185457311854621-CDS,intron-Distal,intron-Proximal4.864758.65197K562RBFOX2
chr11185454811854592-CDS,intron-Distal7.4856031.22845K562AQR
chr11185519811855220-CDS,intron-Distal3.275873.91614K562BUD13
chr11185389211853916-intron-Distal,intron-Proximal5.721839.95272K562AQR
chr11185475711854779-intron-Distal,intron-Proximal5.2169520.70668K562AQR
chr11185096411851008-intron-Distal4.9870818.07708K562AQR
chr11185463211854736-intron-Distal,intron-Proximal4.147134.83721K562EFTUD2
chr11185232411852335-intron-Distal,intron-Proximal4.1829119.00257K562AQR
chr11185646211856508-intron-Distal,intron-Proximal3.879513.25678HepG2SF3B4
chr11185614611856191-intron-Distal,intron-Proximal5.319797.63570K562AQR
chr11185477911854785-intron-Distal,intron-Proximal5.1101418.33116K562AQR
chr11185468011854752-intron-Distal,intron-Proximal4.091959.53843K562PRPF8
chr11185121911851263-intron-Distal,intron-Proximal5.3802649.32632K562AQR
chr11185468011854746-intron-Distal,intron-Proximal3.456469.51392K562TIA1
chr11185512011855155-intron-Distal,intron-Proximal5.0429427.53657K562AQR
chr11185465911854718-intron-Distal,intron-Proximal3.972485.86205K562DROSHA
chr11186039311860454-intron-Distal,intron-Proximal3.114915.24703K562BUD13
chr11185116111851222-intron-Distal,intron-Proximal3.048264.80218K562UCHL5
chr11185467411854750-intron-Distal,intron-Proximal5.6558812.14650K562RBM15
chr11185462111854756-intron-Distal,intron-Proximal6.6720943.47446K562RBFOX2
chr11185117311851219-intron-Distal,intron-Proximal3.8911515.01764K562AQR
chr11185462411854754-intron-Distal,intron-Proximal3.3687511.75242K562BUD13
chr11185510611855120-intron-Distal,intron-Proximal6.2864728.30622K562AQR
chr11185394011853963-intron-Distal,intron-Proximal4.6793112.35151K562AQR
chr11186108411861134-intron-Distal,intron-Proximal3.806634.80676K562RBM15
chr11185739911857453-intron-Distal3.152723.40391K562XRCC6
chr11185189911851945-intron-Distal3.757375.83621K562AQR
chr11185434511854415-intron-Distal,intron-Proximal4.3228345.26410K562AQR
chr11186040211860430-intron-Distal,intron-Proximal6.0864623.96022K562SF3B4
chr11185646711856514-intron-Distal,intron-Proximal3.343633.63681K562RBM15
chr11185391611853940-intron-Distal,intron-Proximal5.7289021.23371K562AQR
chr11185464011854748-intron-Distal,intron-Proximal4.030806.55430HepG2RBFOX2
chr11185434411854403-intron-Distal,intron-Proximal3.791739.05957K562BUD13
chr11185649711856508-intron-Distal,intron-Proximal6.6567953.01092K562SF3B4
chr11185470611854757-intron-Distal,intron-Proximal4.1793125.97102K562AQR
chr11185229211852324-intron-Distal,intron-Proximal5.3629920.18526K562AQR
chr11185117711851250-intron-Distal,intron-Proximal3.587884.14410K562AKAP8L
chr11185948811859576-intron-Distal3.203833.62729K562HNRNPK
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for MTHFR is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for MTHFR is not available on ENCORE database.

  • 139 RBPs can affect the levels of MTHFR.  








The Knockdown/knockout RNA-Seq assay for MTHFR is not available on ENCORE database.





139 RBPs can affect the gene expression of MTHFR :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
MTHFRENSG00000177000.661.42890128.92720-1.069604.175602.88660HepG2AATF
MTHFRENSG00000177000.6339.74870202.443500.746804.163503.02510HepG2ABCF1
MTHFRENSG00000177000.6154.50170271.64020-0.814106.294705.45390HepG2ACO1
MTHFRENSG00000177000.6361.92470541.76960-0.582003.330902.75490HepG2AKAP1
MTHFRENSG00000177000.6248.40160129.166000.943303.379901.53610HepG2APOBEC3C
MTHFRENSG00000177000.6278.40410182.748300.607203.122301.62710HepG2ATP5C1
MTHFRENSG00000177000.6463.23780327.683900.499304.024803.22600HepG2AUH
MTHFRENSG00000177000.6423.87020169.387701.3232010.823109.19580HepG2BCLAF1
MTHFRENSG00000177000.6280.59880161.456100.797304.814304.05230HepG2BOP1
MTHFRENSG00000177000.6212.64570124.675000.770203.965203.06580HepG2CALR
MTHFRENSG00000177000.6278.46930143.804300.953305.154603.80440HepG2CCAR1
MTHFRENSG00000177000.6345.54030138.344401.320508.626607.29950HepG2CNOT7
MTHFRENSG00000177000.6266.11500148.229300.844104.855003.96530HepG2CPSF6
MTHFRENSG00000177000.6399.36150187.804401.0884014.4424012.97650HepG2DAZAP1
MTHFRENSG00000177000.6400.62400142.107101.4952017.0049015.49700HepG2DDX21
MTHFRENSG00000177000.6245.54490139.177800.819004.816303.60010HepG2DDX24
MTHFRENSG00000177000.6329.65810175.092600.912806.724005.20410HepG2DDX5
MTHFRENSG00000177000.6288.52340445.90350-0.628003.515602.82700HepG2DDX6
MTHFRENSG00000177000.6232.6418092.621801.3286010.170008.42900HepG2DHX30
MTHFRENSG00000177000.6422.07050259.884600.699506.221005.28320HepG2DKC1
MTHFRENSG00000177000.6261.8395096.029301.4470014.0416012.55620HepG2DNAJC21
MTHFRENSG00000177000.6141.1433095.188200.568202.258001.65620HepG2DNAJC2
MTHFRENSG00000177000.6245.79980139.358100.818603.974802.88960HepG2EEF2
MTHFRENSG00000177000.6646.94230428.511200.594204.149703.43210HepG2EIF2S1
MTHFRENSG00000177000.6231.37320134.273900.784904.487603.14930HepG2EIF3G
MTHFRENSG00000177000.61229.43080473.484301.3765021.0928019.36440HepG2EIF4A3
MTHFRENSG00000177000.6316.55530185.294300.772506.093504.93930HepG2EIF4G1
MTHFRENSG00000177000.6406.98770177.497601.1971012.1339010.50460HepG2EIF4G2
MTHFRENSG00000177000.6267.51130175.395200.608902.957501.83090HepG2ESF1
MTHFRENSG00000177000.6602.86670376.212900.680208.022707.09020HepG2ETF1
MTHFRENSG00000177000.6297.14840148.475501.000902.762901.74860HepG2FTO
MTHFRENSG00000177000.6348.92440477.94050-0.453902.507801.84770HepG2FXR1
MTHFRENSG00000177000.6597.03160443.247000.429602.341001.72590HepG2G3BP1
MTHFRENSG00000177000.6664.34340470.711000.497003.262702.29070HepG2G3BP2
MTHFRENSG00000177000.6175.92070100.743200.804103.643802.60420HepG2GEMIN5
MTHFRENSG00000177000.6605.65290168.039801.8496025.8380024.10600HepG2GPKOW
MTHFRENSG00000177000.6310.7979096.949401.6806016.3195014.96060HepG2HNRNPA1
MTHFRENSG00000177000.6432.94900107.840602.0052025.9691024.10650HepG2HNRNPC
MTHFRENSG00000177000.6308.69290184.750000.740505.630804.65200HepG2HNRNPF
MTHFRENSG00000177000.6236.36750449.09130-0.926007.722806.60050HepG2HNRNPK
MTHFRENSG00000177000.6373.09260160.362601.2181010.527409.39450HepG2HNRNPLL
MTHFRENSG00000177000.6161.10960107.127400.588602.465701.89190HepG2HNRNPU
MTHFRENSG00000177000.6360.63330181.925200.987109.147307.90030HepG2IGF2BP1
MTHFRENSG00000177000.6828.37460450.510700.878609.201008.04920HepG2IGF2BP2
MTHFRENSG00000177000.6279.31440134.837401.050603.715502.15640HepG2ILF3
MTHFRENSG00000177000.6365.85170151.816001.268809.690508.13870HepG2LARP4
MTHFRENSG00000177000.6247.40150165.717000.578002.544801.38480HepG2LIN28B
MTHFRENSG00000177000.6683.52380478.108300.515603.437002.70530HepG2MAGOH
MTHFRENSG00000177000.6343.70470480.74930-0.484102.455701.85850HepG2MATR3
MTHFRENSG00000177000.6324.25270163.526300.987505.333903.96310HepG2MTPAP
MTHFRENSG00000177000.6741.75360492.045200.592004.232403.45460HepG2NCBP2
MTHFRENSG00000177000.6336.14050176.115800.932403.671502.39910HepG2NONO
MTHFRENSG00000177000.6234.46030126.388200.891402.749901.86510HepG2PABPC1
MTHFRENSG00000177000.6710.37580438.068000.697305.816304.78280HepG2PABPC4
MTHFRENSG00000177000.6262.61920146.410300.842904.207502.94250HepG2PCBP2
MTHFRENSG00000177000.6244.48830174.102200.489702.383301.65880HepG2PRPF4
MTHFRENSG00000177000.6256.34170153.902200.736003.154701.86150HepG2PRPF6
MTHFRENSG00000177000.6493.12610177.774701.4718020.3528018.93460HepG2PUF60
MTHFRENSG00000177000.6261.51320188.720900.470502.785002.19070HepG2PUM1
MTHFRENSG00000177000.6268.53920188.579800.509902.558901.91330HepG2PUM2
MTHFRENSG00000177000.6639.16250276.682301.2079023.4165021.94960HepG2PUS1
MTHFRENSG00000177000.6727.78900482.709100.592305.929405.06300HepG2QKI
MTHFRENSG00000177000.6153.93510244.37980-0.666804.133903.11050HepG2RBM15
MTHFRENSG00000177000.6281.05930190.326600.562302.445601.51870HepG2RBM27
MTHFRENSG00000177000.6250.80750154.553700.698402.805801.73840HepG2RCC2
MTHFRENSG00000177000.6403.46880496.00140-0.297901.780601.32630HepG2NELFE
MTHFRENSG00000177000.6331.79870461.93020-0.477403.627602.93430HepG2RECQL
MTHFRENSG00000177000.6313.41780199.032900.655003.757402.98090HepG2RPLP0
MTHFRENSG00000177000.6421.64080138.819601.6027014.4723012.50880HepG2RPS10
MTHFRENSG00000177000.6189.72450110.078700.785303.689902.99020HepG2RPS19
MTHFRENSG00000177000.6310.77740175.529400.824104.911403.86370HepG2RPS2
MTHFRENSG00000177000.6431.74480138.739001.6377015.9204014.06230HepG2RPS3A
MTHFRENSG00000177000.6214.97150110.503300.960005.339204.04200HepG2SERBP1
MTHFRENSG00000177000.6277.17940421.51750-0.604803.193202.46720HepG2SF3A3
MTHFRENSG00000177000.6336.68660158.733301.084708.819107.62860HepG2SF3B1
MTHFRENSG00000177000.6330.52780170.468800.955209.597608.41550HepG2SLBP
MTHFRENSG00000177000.6283.70450137.882601.040804.077802.15240HepG2SLTM
MTHFRENSG00000177000.6198.58410111.250700.835805.011804.18910HepG2SMN1
MTHFRENSG00000177000.6381.38540484.33480-0.344802.178501.74520HepG2SRSF1
MTHFRENSG00000177000.6274.20370175.532800.643404.248303.50160HepG2SRSF5
MTHFRENSG00000177000.6288.65700181.513500.669204.543803.68500HepG2SRSF7
MTHFRENSG00000177000.6818.79170308.371201.4087035.7886034.42690HepG2SSB
MTHFRENSG00000177000.6241.26380136.580700.820804.236702.73270HepG2STAU1
MTHFRENSG00000177000.6207.32630120.626100.781303.655002.37280HepG2STIP1
MTHFRENSG00000177000.6309.37840199.623900.632004.563003.80090HepG2SUCLG1
MTHFRENSG00000177000.6274.41930138.073700.990807.474905.98600HepG2SUPT6H
MTHFRENSG00000177000.6422.56530190.824501.146807.860206.81430HepG2SUPV3L1
MTHFRENSG00000177000.6265.84760435.30160-0.711404.857704.14770HepG2TAF15
MTHFRENSG00000177000.6267.27160156.276300.774104.339503.45780HepG2TARDBP
MTHFRENSG00000177000.6649.98770271.845601.257507.367105.72280HepG2TBRG4
MTHFRENSG00000177000.6299.39000400.02250-0.418102.550501.74540HepG2TIA1
MTHFRENSG00000177000.6278.33650104.085701.4190013.4262012.46500HepG2TIAL1
MTHFRENSG00000177000.6252.11520105.025401.2632011.7848010.73820HepG2TRIM56
MTHFRENSG00000177000.6262.48720173.686800.595702.116001.36010HepG2TUFM
MTHFRENSG00000177000.6281.20520174.897600.685003.566702.85790HepG2U2AF1
MTHFRENSG00000177000.6330.18030183.850300.844603.512302.56510HepG2UBE2L3
MTHFRENSG00000177000.6597.95860373.822400.677608.380707.27430HepG2UPF1
MTHFRENSG00000177000.6288.53420124.258901.215304.986303.49910HepG2XPO5
MTHFRENSG00000177000.61279.226204458.74940-1.8014017.1573015.86750K562AGGF1
MTHFRENSG00000177000.63533.280404898.77720-0.471402.170501.31270K562AKAP8
MTHFRENSG00000177000.62346.689604639.35510-0.983306.993205.91500K562AKAP8L
MTHFRENSG00000177000.63336.865604352.84930-0.383504.513103.79720K562AQR
MTHFRENSG00000177000.63443.893804867.46820-0.499102.908901.97390K562ATP5C1
MTHFRENSG00000177000.63488.988002657.259600.392808.583606.86040K562BCLAF1
MTHFRENSG00000177000.62733.075402015.926800.439007.338005.49570K562CSTF2
MTHFRENSG00000177000.63416.865302883.272600.244902.809501.58830K562DDX21
MTHFRENSG00000177000.62619.913703440.91190-0.393307.792706.77510K562DDX47
MTHFRENSG00000177000.62480.388204993.38040-1.009508.242506.58380K562DKC1
MTHFRENSG00000177000.61180.525301799.12730-0.607903.775102.57960K562EIF3A
MTHFRENSG00000177000.62074.159402675.50500-0.367302.719001.69340K562EIF3D
MTHFRENSG00000177000.61855.137702338.95840-0.334302.181801.46940K562EIF3G
MTHFRENSG00000177000.66043.654905014.297800.269303.883202.77280K562EIF4G2
MTHFRENSG00000177000.62881.862402215.509700.379304.576102.90010K562EXOSC5
MTHFRENSG00000177000.61259.537201899.79250-0.592904.377902.90420K562FKBP4
MTHFRENSG00000177000.61691.663002067.74230-0.289603.185301.73660K562FUS
MTHFRENSG00000177000.6687.090901151.44510-0.744903.097902.34170K562G3BP2
MTHFRENSG00000177000.63236.177802506.050000.368802.789701.36510K562GEMIN5
MTHFRENSG00000177000.62201.281901627.884200.435204.778103.73820K562GPKOW
MTHFRENSG00000177000.63107.633504667.62030-0.5869010.103608.63600K562GRSF1
MTHFRENSG00000177000.62197.029003470.60750-0.659603.593801.36460K562HLTF
MTHFRENSG00000177000.61487.219403493.26570-1.232006.066204.00360K562HNRNPA2B1
MTHFRENSG00000177000.64254.858302186.620800.9603025.1407023.41330K562HNRNPC
MTHFRENSG00000177000.63933.789003109.661400.339103.733702.48010K562HNRNPL
MTHFRENSG00000177000.62175.817904924.13130-1.178307.066205.60280K562KIF1C
MTHFRENSG00000177000.61825.100401390.139200.392602.304001.46050K562KRR1
MTHFRENSG00000177000.62778.767404713.10570-0.762203.625602.33960K562MAK16
MTHFRENSG00000177000.63584.641902657.502100.431703.330502.30620K562MATR3
MTHFRENSG00000177000.62722.220805516.18480-1.018905.967604.53530K562MBNL1
MTHFRENSG00000177000.61628.464603866.39190-1.247505.767204.32780K562NAA15
MTHFRENSG00000177000.63231.878602464.739400.390803.083701.69740K562NONO
MTHFRENSG00000177000.63908.340403209.960000.283907.226606.10210K562NSUN2
MTHFRENSG00000177000.64346.272702757.806600.656204.606902.98080K562PABPC1
MTHFRENSG00000177000.61433.177403057.28980-1.093004.361903.04450K562PABPN1
MTHFRENSG00000177000.61298.906702369.22690-0.867104.486003.23420K562PCBP2
MTHFRENSG00000177000.66255.569805152.355900.279803.305801.73860K562PNPT1
MTHFRENSG00000177000.62715.424502161.662700.328903.621902.69920K562POLR2G
MTHFRENSG00000177000.61290.948602432.37460-0.913909.573608.17480K562PRPF8
MTHFRENSG00000177000.61058.001004602.22460-2.1210020.2412018.80080K562PUS1
MTHFRENSG00000177000.6588.668501098.71970-0.900305.571503.45390K562RAVER1
MTHFRENSG00000177000.61612.728904483.13260-1.4750012.2727011.02710K562RBM15
MTHFRENSG00000177000.63456.973002418.498700.515302.888201.47280K562RBM34
MTHFRENSG00000177000.62707.024601789.373400.597208.077906.38440K562RCC2
MTHFRENSG00000177000.63557.740402610.173700.446703.306102.09880K562NELFE
MTHFRENSG00000177000.61283.248902477.09470-0.9488010.316008.71340K562RPS19
MTHFRENSG00000177000.62422.804301925.892300.331103.241502.06900K562SAFB
MTHFRENSG00000177000.61119.926402796.93220-1.320406.035404.04810K562SF1
MTHFRENSG00000177000.64242.470102685.722400.659505.153002.72360K562SMN1
MTHFRENSG00000177000.61231.511903210.60850-1.382406.404804.27010K562SNRNP200
MTHFRENSG00000177000.63283.497002429.622100.434404.248902.17610K562SRP68
MTHFRENSG00000177000.62269.022401485.598600.610902.370201.40620K562SRSF4
MTHFRENSG00000177000.62428.919103035.88300-0.321802.722301.37640K562SSRP1
MTHFRENSG00000177000.64584.935802567.092900.836709.017907.64500K562TARDBP
MTHFRENSG00000177000.63815.546402476.384300.623606.137904.84930K562TIA1
MTHFRENSG00000177000.62592.594602003.964000.371403.731402.60210K562TRIM56
MTHFRENSG00000177000.6555.264401116.64620-1.0079012.126009.63710K562U2AF1
MTHFRENSG00000177000.6769.196501153.08180-0.584107.621906.28330K562U2AF2
MTHFRENSG00000177000.63298.470102491.994300.404403.501202.34850K562UCHL5
MTHFRENSG00000177000.64551.710303403.600400.4192010.600409.30790K562UPF1
MTHFRENSG00000177000.62155.395304664.90430-1.113904.422002.64830K562UTP18
MTHFRENSG00000177000.64060.636803067.879700.404403.164101.87230K562UTP3
MTHFRENSG00000177000.62616.144203028.62180-0.211202.925702.05550K562WDR43
MTHFRENSG00000177000.64154.273605157.04190-0.311903.424401.97820K562WRN
MTHFRENSG00000177000.63669.672002538.326600.531705.041903.23000K562XRN2
MTHFRENSG00000177000.62064.458303779.47920-0.872403.488701.63650K562YTHDC2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for MTHFR is not available on ENCORE database.





2 RBPs can affect the splicing of MTHFR :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
A3SSMTHFRENSG00000177000.6chr1-1186126111861473118612611186145611862937118631860.180000.000020.00152longerK562U2AF2
A3SSMTHFRENSG00000177000.6chr1-1185396311854167118539631185414611854414118546300.076000.000070.00065longerK562AQR
A3SSMTHFRENSG00000177000.6chr1-1186026811860479118602681186037911861217118614560.055000.018730.09012longerK562AQR
A3SSMTHFRENSG00000177000.6chr1-1186126111861473118612611186145611862937118631860.079000.000030.00031longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for MTHFR is not avaliable on ENCORE database.