UBE2L3

General Information

Gene Name       : UBE2L3
Gene ID             : ENSG00000185651.14
Essential Gene : Yes

Functions

Localization(RBPImage: UBE2L3)

Domains (AlphaFold: UBE2L3)


Antibody Validation

 View validation images for all UBE2L3 antibodies

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878UBE2L3ENSG00000185651.1498.4095.9997.19ENCSR000AEF
HepG2UBE2L3ENSG00000185651.1440.8367.4754.15ENCSR985KAT
K562UBE2L3ENSG00000185651.14356.34390.08373.21ENCSR000AEO

Assays

2 Released experiments are available on ENCORE database.

Assay TypeExp_NameENCODE IDTarget labelBiosampleStatusLinked AntibodyControlsMethodNote
knockdown followed by RNA-seq UBE2L3-BGKLV25-K562ENCSR362XMYUBE2L3K562ReleasedENCSR620PUP   shRNAKD% = 69.4,60.0
knockdown followed by RNA-seq UBE2L3-BGHLV23-HepG2ENCSR424JSUUBE2L3HepG2ReleasedENCSR042QTH   shRNAKD% = 76.6,85.6






  eCLIP  

No eCLIP experiment available



  Antibody Validation  
  GeneName    Antibody_DCC_ID    Product_ID    Lot_ID    Phosphate    HepG2 Primary Validation    K562 Primary Validation    HepG2 Secondary Validation    K562 Secondary Validation  
UBE2L3ENCAB492XKEA300-737A1Released, ENCODE4BGHLV23-57, Released, ENCODE3BGKLV25-61, Released, ENCODE3
UBE2L38721S1Submitted, ENCORE2BGHLV23-57, Released, ENCODE3BGKLV25-61, Submitted, ENCORE2


  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
UBE2L3K562shRNABGKLV13-5,BGKLV13-6BGKLV13-1,BGKLV13-2NotSatisfiedENCODE3
UBE2L3K562shRNAENCSR362XMYENCSR620PUPUBE2L3-BGKLV25-61,UBE2L3-BGKLV25-62NT_BGKLV25-1,NT_BGKLV25-269.4,60.0ReleasedENCODE3
UBE2L3HepG2shRNAENCSR424JSUENCSR042QTHUBE2L3-BGHLV23-57,UBE2L3-BGHLV23-58non-target-BGHLV23-1,non-target-BGHLV23-276.6,85.6ReleasedENCODE3
UBE2L3K562CRISPRBGKcLV17-51,BGKcLV17-52BGKcLV17-1,BGKcLV17-2NotSatisfiedENCODE4
UBE2L3K562CRISPRBGKcLV17-53,BGKcLV17-54BGKcLV17-1,BGKcLV17-2NotSatisfiedENCODE4


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  
    UBE2L3: Click to RBP Image Database
  • Nuclei
  • Nucleoplasm
  • Mutually Exclusive from Nucleolus
  • Cytoplasm
  • Compartment/Organelle
  • Mitochondria
  • Cytosolic












    • RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela
    UBE2L3Product_ID: A300-737A
    Lot_ID: 1
    Source: Bethyl Labs
    Target Name: UBE2L3-human    		 UBE2L3_Secondary_Western.png<br>Caption: Western blot following shRNA against UBE2L3 in K562 and HepG2 whole cell lysate using UBE2L3 specific antibody. Lane 1 is a ladder, lane 2 is K562 non-targeting control knockdown, lane 3 and 4 are two different shRNAs against UBE2L3. Lanes 5-8 follow the same pattern, but in HepG2. UBE2L3 protein appears as the green band, Tubulin serves as a control and appears in red.
    		 Bethyl_A300-737A_1_UBCH7.png<br>Caption: IP-WB analysis of K562 whole cell lysate using the UBCH7 specific antibody, A300-737A. Lane 1 is 2.5% of five million whole cell lysate input. Lanes 2 and 3 are 50% of IP enrichment from five million whole cell lysate using normal IgG antibody and the UBCH7-specific antibody, A300-737A. The same antibody was used to detect protein levels via Western blot. This antibody passes preliminary validation and will be further pursued for secondary validation. *NOTE* Protein sizes are taken from Genecards.org and are only estimates based on sequence. Actual protein size may differ based on protein characteristics and electrophoresis method used.
    		 UBE2L3_Secondary_Western.png<br>Caption: Western blot following shRNA against UBE2L3 in K562 and HepG2 whole cell lysate using UBE2L3 specific antibody. Lane 1 is a ladder, lane 2 is K562 non-targeting control knockdown, lane 3 and 4 are two different shRNAs against UBE2L3. Lanes 5-8 follow the same pattern, but in HepG2. UBE2L3 protein appears as the green band, Tubulin serves as a control and appears in red.
    UBE2L3Product_ID: 8721S
    Lot_ID: 1
    Source: Cell Signaling Technology
    Target Name: UBE2L3-human    		 CST_8721S_1_UBE2L3.png<br>Caption: IP-WB analysis of 8721S whole cell lysate using the UBE2L3 specific antibody, 8721S. Lanes 1 and 2 are 2.5% of five million whole cell lysate input and 50% of IP enrichment, respectively, using a normal IgG antibody. Lane 3 is 50% of IP enrichment from five million whole cell lysate using the UBE2L3-specific antibody, 8721S. The same antibody was used to detect protein levels via Western blot. This antibody passes preliminary validation and will be further pursued for secondary validation. *NOTE* Protein sizes are taken from Genecards.org and are only estimates based on sequence. Actual protein size may differ based on protein characteristics and electrophoresis method used.
    		 UBE2L3-K562-8721S.png<br>Caption: Western blot following shRNA against UBE2L3 in K562 whole cell lysate using UBE2L3 specific antibody. Lane 1 is a ladder, lane 2 is K562 non-targeting control knockdown, lane 3 and 4 are two different shRNA against UBE2L3. UBE2L3 protein appears as the green arrow, Beta-actin serves as a control and appears in red arrow.








    RNA Targets

    • eCLIP assay for UBE2L3 is not avaliable on ENCORE database.



    Proteins bound to RNA
    • UBE2L3 RNA is bound by 34 proteins.  







    eCLIP assay for UBE2L3 is not avaliable on ENCORE database.





    34 proteins are bound to UBE2L3 RNA:

    Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
    chr222197696521977045+3'-UTR4.5233247.59714K562UPF1
    chr222197746121977550+3'-UTR4.4882642.87762K562UPF1
    chr222197786921977911+3'-UTR4.922006.60913K562IGF2BP2
    chr222197647921976509+3'-UTR5.1942824.20857K562UPF1
    chr222197687621976964+3'-UTR3.5960030.42042K562UPF1
    chr222197666321976740+3'-UTR4.4758534.94974K562FAM120A
    chr222197651921976599+3'-UTR3.4980510.54783K562FAM120A
    chr222197629721976355+3'-UTR3.2848016.52498K562FAM120A
    chr222197618921976221+3'-UTR3.774684.76828K562IGF2BP1
    chr222197663021976663+3'-UTR3.361989.62331K562FAM120A
    chr222197689021976921+3'-UTR3.7405132.00889K562YBX3
    chr222197719221977243+3'-UTR4.3845235.76662K562UPF1
    chr222197636521976444+3'-UTR3.4241822.25059K562IGF2BP2
    chr222197684921976869+3'-UTR3.8492718.19224K562YBX3
    chr222197652021976612+3'-UTR3.3802045.54717K562UPF1
    chr222197717421977192+3'-UTR4.7137422.76666K562UPF1
    chr222197788421977942+3'-UTR3.426945.56056K562AKAP1
    chr222197746921977545+3'-UTR3.555699.53837K562TIA1
    chr222197686921976886+3'-UTR3.2823821.41492K562YBX3
    chr222197680121976837+3'-UTR4.0698223.53091K562YBX3
    chr222197635821976415+3'-UTR4.023016.86497HepG2UPF1
    chr222197676821976807+3'-UTR5.0311838.23088K562UPF1
    chr222197697521977075+3'-UTR4.9451020.99317K562RBM15
    chr222197680721976856+3'-UTR3.9867223.10023K562UPF1
    chr222197704521977078+3'-UTR3.6682518.54029K562UPF1
    chr222197626221976351+3'-UTR3.4958236.97997K562PABPC4
    chr222197683721976849+3'-UTR3.8905612.80947K562YBX3
    chr222197761921977657+3'-UTR4.1488919.10057K562UPF1
    chr222197635521976440+3'-UTR3.5525043.30456K562FAM120A
    chr222197690221976953+3'-UTR3.126234.29961K562METAP2
    chr222197674021976790+3'-UTR4.0653720.11444K562FAM120A
    chr222197773721977841+3'-UTR5.0999718.64858K562IGF2BP1
    chr222197642021976479+3'-UTR5.4778052.29945K562UPF1
    chr222197635421976420+3'-UTR3.8230372.44811K562UPF1
    chr222197686821976965+3'-UTR4.5895613.65779K562RBM15
    chr222197628821976362+3'-UTR4.222223.88460HepG2PCBP2
    chr222197622121976294+3'-UTR5.5100137.84869K562IGF2BP1
    chr222197699821977070+3'-UTR4.199833.45012HepG2UPF1
    chr222197659921976630+3'-UTR3.724627.89120K562FAM120A
    chr222197700721977060+3'-UTR3.7721918.60476K562IGF2BP2
    chr222197698621977086+3'-UTR3.5416422.60189K562FAM120A
    chr222197709721977142+3'-UTR3.9282724.53128K562UPF1
    chr222197630521976352+3'-UTR3.800276.53690K562PCBP1
    chr222197692121976967+3'-UTR3.6747322.90396K562YBX3
    chr222197667221976745+3'-UTR5.1353772.58334K562UPF1
    chr222197709021977115+3'-UTR4.231386.12175K562AKAP1
    chr222197662521976672+3'-UTR5.1702429.14819K562UPF1
    chr222197635821976400+3'-UTR4.079843.34655HepG2AKAP1
    chr222197669321976776+3'-UTR4.943639.13781K562AKAP1
    chr222194723321947293+CDS,intron-Distal,intron-Proximal3.4764117.20713K562PRPF8
    chr222194721221947274+CDS,intron-Distal,intron-Proximal4.450553.86479HepG2PRPF8
    chr222192203521922117+CDS,intron-Distal,intron-Proximal3.016994.04132HepG2PRPF8
    chr222197573021975864+CDS,intron-Proximal5.126766.03362HepG2AQR
    chr222196525421965330+CDS3.5862314.08559K562RPS3
    chr222194723821947292+CDS,intron-Distal,intron-Proximal3.058819.16958K562AQR
    chr222192205721922103+CDS,intron-Distal,intron-Proximal4.406474.28193HepG2AQR
    chr222197581521975871+CDS3.535278.05052K562RPS3
    chr222197580221975873+CDS,intron-Proximal3.765728.60016K562PUM1
    chr222196514021965219+CDS,intron-Proximal3.206084.71502HepG2GRWD1
    chr222197573821975816+CDS,intron-Proximal3.6148310.24099K562SF3B4
    chr222192205921922107+CDS,intron-Distal,intron-Proximal3.8323716.10216K562AQR
    chr222196533121965339+CDS,intron-Proximal7.0265927.93134K562AQR
    chr222197576221975821+CDS,intron-Proximal4.0157622.86236K562AQR
    chr222193566721935726+intron-Distal3.564545.09850K562ILF3
    chr222192438321924497+intron-Distal4.7072513.49215K562MATR3
    chr222194767621947812+intron-Distal5.377867.79030HepG2PCBP2
    chr222196457921964710+intron-Distal3.584525.84939K562HNRNPL
    chr222193295421933038+intron-Distal5.042139.29051K562NONO
    chr222194833721948480+intron-Distal4.2986718.96104K562MATR3
    chr222192799621928059+intron-Distal4.107657.83327K562NONO
    chr222194839821948485+intron-Distal4.015845.07626HepG2PTBP1
    chr222194776921947838+intron-Distal4.6737911.27866K562HNRNPK
    chr222194770521947769+intron-Distal4.3052014.57480K562HNRNPK
    chr222192285321922888+intron-Distal4.170414.23759K562NONO
    chr222194251221942580+intron-Distal3.783295.97215K562MATR3
    chr222193713121937201+intron-Distal4.703415.31905K562ILF3
    chr222193745521937590+intron-Distal3.903806.71800K562MATR3
    chr222194838521948487+intron-Distal3.7786126.34771K562PTBP1
    chr222194866821948709+intron-Distal3.255945.34991K562HNRNPM
    chr222194772521947827+intron-Distal3.245023.60809HepG2HNRNPK
    chr222194793821948056+intron-Distal4.7353619.45942K562HNRNPK
    chr222194417821944254+intron-Distal3.493074.24981K562MATR3
    chr222193286521932910+intron-Distal3.105004.37857K562HNRNPM
    chr222193277221932865+intron-Distal4.9238116.28748K562HNRNPM
    chr222194872921948775+intron-Distal4.347329.78023K562HNRNPM
    chr222196536421965450+intron-Distal,intron-Proximal3.076128.88817K562EFTUD2
    chr222194788321947936+intron-Distal4.9167415.60300K562PTBP1
    chr222194904521949086+intron-Distal4.052383.34098HepG2HNRNPM
    chr222196589621965980+intron-Distal4.6146210.79749K562TARDBP
    chr222192423521924301+intron-Distal4.654036.48506K562MATR3
    chr222192259521922664+intron-Distal3.690866.82477K562EFTUD2
    chr222194815121948208+intron-Distal3.5609610.83203K562PTBP1
    chr222192724921927326+intron-Distal3.692359.24620K562HNRNPK
    chr222194933321949373+intron-Distal3.733758.74030K562HNRNPM
    chr222193298421933035+intron-Distal4.497945.04680K562HNRNPM
    chr222192221021922321+intron-Distal4.683998.40379HepG2XPO5
    chr222194233121942390+intron-Distal3.306293.98203K562MATR3
    chr222192390521923997+intron-Distal4.820746.19517K562MATR3
    chr222194385021943930+intron-Distal4.611325.26569K562MATR3
    chr222192723021927306+intron-Distal3.456073.98203K562MATR3
    chr222196059521960677+intron-Distal3.482587.05065K562TARDBP
    chr222194795221948028+intron-Distal3.941803.06084HepG2HNRNPK
    chr222193956621939627+intron-Distal3.902753.57432K562NONO
    chr222194920921949319+intron-Distal4.878415.37406HepG2HNRNPM
    chr222194623221946317+intron-Distal3.421734.05280K562CSTF2T
    chr222194921021949241+intron-Distal5.6961512.04872K562HNRNPM
    chr222194770821947801+intron-Distal3.988559.86758K562MATR3
    chr222196588921965943+intron-Distal3.204803.39857HepG2HNRNPM
    chr222194939121949461+intron-Distal3.553459.46368K562HNRNPM
    chr222196215921962201+intron-Distal4.023313.31709K562ILF3
    chr222194786821947943+intron-Distal5.307759.85433K562MATR3
    chr222194762421947730+intron-Distal3.9880211.46790K562PTBP1
    chr222192210721922143+intron-Distal,intron-Proximal4.300456.99120K562AQR
    chr222196059821960687+intron-Distal4.256006.94650K562EIF4G2
    chr222197433421974428+intron-Distal3.145366.66758K562ILF3
    chr222192259421922682+intron-Distal,intron-Proximal3.3001311.54496K562NONO
    chr222193013621930209+intron-Distal4.709295.86170K562ILF3
    chr222192879021928881+intron-Distal3.127547.12738K562ILF3
    chr222194903621949116+intron-Distal4.8624421.68236K562HNRNPM
    chr222193574221935778+intron-Distal3.699863.06194K562ILF3
    chr222196134121961381+intron-Distal3.280603.37821K562ILF3
    chr222194898321949036+intron-Distal3.0883913.44055K562HNRNPM
    chr222194827321948337+intron-Distal5.038928.23486K562MATR3
    chr222194752421947572+intron-Distal4.607485.01208K562MATR3
    chr222193725521937315+intron-Distal4.061603.06617K562HNRNPK
    chr222193649221936586+intron-Distal3.324588.32978K562ILF3
    chr222193275021932882+intron-Distal4.035515.89423HepG2HNRNPM
    chr222194762721947678+intron-Distal3.762655.22442K562MATR3
    chr222194897721949032+intron-Distal3.389893.18845HepG2HNRNPM
    chr222192253321922567+intron-Distal3.225933.77567K562NONO
    chr222192794121927996+intron-Distal3.362955.87723K562NONO
    chr222192872921928790+intron-Distal3.975546.34081K562ILF3
    chr222192914221929201+intron-Distal3.683065.91713K562ILF3
    chr222192781821927889+intron-Distal3.946687.24988K562NONO
    chr222196536521965470+intron-Distal,intron-Proximal3.0575613.33971K562PRPF8
    chr222192222421922340+intron-Distal3.329864.76816K562XRN2
    chr222194258021942650+intron-Distal4.431943.98115K562MATR3
    chr222192239621922460+intron-Distal3.573803.01619K562FUS
    chr222194924121949310+intron-Distal4.9858125.57387K562HNRNPM
    chr222196537621965420+intron-Proximal4.5251631.35304K562AQR
    chr222196513321965143+intron-Proximal4.004468.16979K562U2AF2
    chr222196535321965399+intron-Proximal3.523584.01163K562RBM15
    chr222196535221965414+intron-Proximal3.2547710.34054K562GPKOW
    chr222196536121965410+intron-Proximal3.660094.06931K562XRN2
    chr222196533921965376+intron-Proximal5.7903453.91840K562AQR
    ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




    eCLIP assay for UBE2L3 is not avaliable on ENCORE database.



    Diffrential Expression
    • 5,805 differentially expressed genes after Knockdown/Knockout UBE2L3 protein.  





    • 92 RBPs can affect the levels of UBE2L3.  







    5,805 differentially expressed genes after Knockdown/Knockout UBE2L3 protein :

    Only display 100 entries as example. Please click "View All" button to see all 5,805 entries.     

    Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
    TSPAN6ENSG00000000003.10733.577702997.20670-2.0306056.3505053.20240HepG2UBE2L3
    C1orf112ENSG00000000460.12323.96570558.46390-0.785605.402104.21390HepG2UBE2L3
    FUCA2ENSG00000001036.92252.193104934.60820-1.1316022.5736020.24430HepG2UBE2L3
    CYP51A1ENSG00000001630.113631.177805068.70290-0.481204.904003.76630HepG2UBE2L3
    BADENSG00000002330.9178.1685094.693100.911803.368202.44570HepG2UBE2L3
    LASP1ENSG00000002834.1314016.867108893.119800.656308.454106.96100HepG2UBE2L3
    DBNDD1ENSG00000003249.91418.11160816.122900.797005.564804.35280HepG2UBE2L3
    ALS2ENSG00000003393.101830.139801382.919400.404102.659901.83900HepG2UBE2L3
    TFPIENSG00000003436.1018424.6806010632.697800.793009.979108.35040HepG2UBE2L3
    SLC7A2ENSG00000003989.129196.449106298.647900.545906.032604.76710HepG2UBE2L3
    PLXND1ENSG00000004399.83586.497402271.324300.658902.921102.06240HepG2UBE2L3
    AK2ENSG00000004455.123546.457004459.26930-0.330402.365701.59610HepG2UBE2L3
    KDM1AENSG00000004487.113558.333304923.33680-0.468404.436803.35910HepG2UBE2L3
    RBM6ENSG00000004534.104040.886005113.09610-0.339502.536101.73560HepG2UBE2L3
    NDUFAB1ENSG00000004779.51463.441101996.33770-0.448003.371202.44770HepG2UBE2L3
    UPF1ENSG00000005007.82402.954701859.952200.369402.087801.36700HepG2UBE2L3
    DHX33ENSG00000005100.81273.023601866.94060-0.552404.970503.82600HepG2UBE2L3
    LIG3ENSG00000005156.7679.96610954.22470-0.488903.065402.18630HepG2UBE2L3
    ACSM3ENSG00000005187.7839.262301075.64140-0.358002.082501.36270HepG2UBE2L3
    SPPL2BENSG00000005206.12592.51660367.142900.690402.067701.35020HepG2UBE2L3
    CREBBPENSG00000005339.82080.347301511.335900.460903.906502.90370HepG2UBE2L3
    WDR54ENSG00000005448.12220.49280389.65030-0.821403.062902.18430HepG2UBE2L3
    RHBDD2ENSG00000005486.12925.91840517.388500.839507.124005.75540HepG2UBE2L3
    LAMP2ENSG00000005893.114243.925005519.02710-0.379003.334502.41620HepG2UBE2L3
    ASB4ENSG00000005981.8285.45180177.612500.684402.647901.82830HepG2UBE2L3
    TMEM98ENSG00000006042.71657.416602190.56660-0.402403.036702.16190HepG2UBE2L3
    MAP3K14ENSG00000006062.9732.42370117.808002.6361017.4996015.39530HepG2UBE2L3
    TMEM132AENSG00000006118.101463.44100655.329201.159005.865604.61520HepG2UBE2L3
    CX3CL1ENSG00000006210.62985.049501955.017400.610506.795905.45600HepG2UBE2L3
    TNFRSF12AENSG00000006327.91165.78830681.613800.774205.716804.48600HepG2UBE2L3
    BAIAP2L1ENSG00000006453.91440.794401046.618500.461003.326302.40930HepG2UBE2L3
    GGCTENSG00000006625.13568.47550939.09580-0.724206.030004.76470HepG2UBE2L3
    IFRD1ENSG00000006652.91129.85900857.519500.397802.319201.55800HepG2UBE2L3
    GTF2IRD1ENSG00000006704.6917.80460712.125100.366002.088401.36760HepG2UBE2L3
    ARSDENSG00000006756.11250.60430377.71650-0.591902.100801.37720HepG2UBE2L3
    PNPLA4ENSG00000006757.7164.17660317.25160-0.950405.425804.23280HepG2UBE2L3
    PROM1ENSG00000007062.71325.28900839.264200.659005.978404.71850HepG2UBE2L3
    CCDC124ENSG00000007080.6426.14030238.474000.837402.983002.11560HepG2UBE2L3
    GAS7ENSG00000007237.1450.89500101.09940-0.990202.422401.64290HepG2UBE2L3
    TRAPPC6AENSG00000007255.6174.9109073.268101.255305.428504.23520HepG2UBE2L3
    RPUSD1ENSG00000007376.3306.7042084.340001.862507.540406.13320HepG2UBE2L3
    RHBDF1ENSG00000007384.11472.21500259.163300.865503.593002.63300HepG2UBE2L3
    LUC7LENSG00000007392.121057.182801616.65350-0.612805.690904.46350HepG2UBE2L3
    BAIAP3ENSG00000007516.9379.89720126.860301.582304.004802.98690HepG2UBE2L3
    TSR3ENSG00000007520.3387.37400197.296800.973306.172304.89380HepG2UBE2L3
    PIGQENSG00000007541.10372.32430173.970001.097607.191605.81790HepG2UBE2L3
    PSMB1ENSG00000008018.84253.793805412.01310-0.347402.610301.79720HepG2UBE2L3
    JARID2ENSG00000008083.9748.964001054.04780-0.493003.288202.37670HepG2UBE2L3
    CDK11AENSG00000008128.181039.84910691.663700.588104.687303.57860HepG2UBE2L3
    ADAM22ENSG00000008277.10209.51810297.88000-0.507702.010301.30210HepG2UBE2L3
    AASSENSG00000008311.10307.05280586.15960-0.932807.578606.16860HepG2UBE2L3
    MPNDENSG00000008382.11266.25500187.037000.509402.103501.37920HepG2UBE2L3
    MGST1ENSG00000008394.81169.743102748.30220-1.2323023.3246020.96310HepG2UBE2L3
    ST3GAL1ENSG00000008513.101024.258501602.51360-0.645805.709604.47910HepG2UBE2L3
    IL32ENSG00000008517.125374.036302670.826501.0086018.0725015.93200HepG2UBE2L3
    PKD1ENSG00000008710.131693.28580414.311902.030903.957302.94610HepG2UBE2L3
    MAPK8IP2ENSG00000008735.10226.8637058.511201.9549012.3126010.49350HepG2UBE2L3
    HEATR5BENSG00000008869.71250.20870905.904600.464602.246101.49650HepG2UBE2L3
    RPS20ENSG00000008988.56787.219609350.71620-0.462304.432603.35560HepG2UBE2L3
    UBE3CENSG00000009335.132431.743901799.362100.434403.583202.62400HepG2UBE2L3
    VTA1ENSG00000009844.111791.049002355.50960-0.395203.016502.14380HepG2UBE2L3
    STARD3NLENSG00000010270.9528.06250850.44540-0.687505.451204.25470HepG2UBE2L3
    NCAPD2ENSG00000010292.82736.957605930.44750-1.1156021.5687019.29030HepG2UBE2L3
    IFFO1ENSG00000010295.15582.21500369.577000.655604.341803.27880HepG2UBE2L3
    SEMA3GENSG00000010319.21348.66890758.566900.830109.137307.57900HepG2UBE2L3
    NISCHENSG00000010322.112481.761301380.266900.846304.024103.00360HepG2UBE2L3
    IDSENSG00000010404.131311.77790984.954500.413302.598201.78790HepG2UBE2L3
    HFEENSG00000010704.14169.23720280.15790-0.727203.008102.13640HepG2UBE2L3
    LYPLA2ENSG00000011009.62116.276701094.573000.951106.278504.98500HepG2UBE2L3
    NME2ENSG00000011052.17452.08060275.002600.717002.342401.57720HepG2UBE2L3
    APBA3ENSG00000011132.7295.17650140.298401.073006.013104.74920HepG2UBE2L3
    MKS1ENSG00000011143.12433.41270596.59000-0.461002.206601.46400HepG2UBE2L3
    MBTD1ENSG00000011258.111329.027401955.31870-0.557005.492704.28800HepG2UBE2L3
    TTC19ENSG00000011295.11626.40250825.90150-0.398902.188501.44890HepG2UBE2L3
    ANLNENSG00000011426.62475.066003587.10110-0.535405.747204.51200HepG2UBE2L3
    WIZENSG00000011451.13925.48570382.804101.2735014.2148012.28190HepG2UBE2L3
    BRCA1ENSG00000012048.15906.337001339.48730-0.563604.597703.50000HepG2UBE2L3
    ERCC1ENSG00000012061.11857.67780651.584800.396402.169901.43430HepG2UBE2L3
    CD22ENSG00000012124.10104.2181017.782502.551009.244407.67610HepG2UBE2L3
    NR1H4ENSG00000012504.9271.39980988.84190-1.8653030.7808028.15050HepG2UBE2L3
    CALCOCO1ENSG00000012822.111755.684501354.422200.374302.737201.90460HepG2UBE2L3
    UBR7ENSG00000012963.9541.15290916.36040-0.759906.615305.28950HepG2UBE2L3
    CLDN11ENSG00000013297.6115.70980287.97530-1.315408.002906.55130HepG2UBE2L3
    SLC25A39ENSG00000013306.113578.407502303.077000.635702.611301.79810HepG2UBE2L3
    MVPENSG00000013364.143337.10710905.281101.882105.460104.26210HepG2UBE2L3
    ANGEL1ENSG00000013523.5573.66840874.99870-0.609104.066303.04160HepG2UBE2L3
    DNASE1L1ENSG00000013563.9339.20770194.516200.802202.616701.80290HepG2UBE2L3
    HEBP1ENSG00000013583.4424.81800580.05850-0.449402.251101.50100HepG2UBE2L3
    ZC3H3ENSG00000014164.6477.98490223.894201.094008.202506.73080HepG2UBE2L3
    CAPN1ENSG00000014216.112645.096501752.523800.593803.917902.91270HepG2UBE2L3
    MDH1ENSG00000014641.134304.136005797.30410-0.429704.004502.98680HepG2UBE2L3
    DPEP1ENSG00000015413.546.66370194.86280-2.0621010.992709.28070HepG2UBE2L3
    MATR3ENSG00000015479.137593.3894011628.45180-0.614808.160506.69210HepG2UBE2L3
    XYLT2ENSG00000015532.5953.86620659.699000.531903.866802.87090HepG2UBE2L3
    SRCIN1ENSG00000017373.11640.32230203.094601.6565013.0457011.18310HepG2UBE2L3
    CXorf56ENSG00000018610.9155.13710397.16340-1.3562010.207208.56190HepG2UBE2L3
    ATP1A2ENSG00000018625.100.5169016.52300-4.998503.074402.19370HepG2UBE2L3
    TTC27ENSG00000018699.7789.773801133.23880-0.520904.100203.07140HepG2UBE2L3
    CYP24A1ENSG00000019186.51254.07930913.495000.457103.162202.26780HepG2UBE2L3
    SAMD4AENSG00000020577.92311.718801581.223300.547805.126403.96680HepG2UBE2L3
    Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

    *: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
    **: "-log(0)" was displayed as "99999.99999".





    92 RBPs can affect the gene expression of UBE2L3 :

    Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
    UBE2L3ENSG00000185651.101962.313801617.967700.278303.232702.58310HepG2ACO1
    UBE2L3ENSG00000185651.103028.434603595.63100-0.247701.912601.40700HepG2BOP1
    UBE2L3ENSG00000185651.102002.750303301.02520-0.7209010.974909.70310HepG2CPSF6
    UBE2L3ENSG00000185651.102878.176702537.515600.181601.894701.34400HepG2CELF1
    UBE2L3ENSG00000185651.102301.219202728.38700-0.245603.966103.10410HepG2DAZAP1
    UBE2L3ENSG00000185651.101375.777901838.94530-0.418602.766501.99340HepG2DDX55
    UBE2L3ENSG00000185651.101583.252202030.46840-0.358902.343901.77130HepG2DDX6
    UBE2L3ENSG00000185651.101265.214501725.72670-0.447804.668903.40990HepG2DHX30
    UBE2L3ENSG00000185651.101466.807901789.23630-0.286703.144102.39900HepG2DNAJC21
    UBE2L3ENSG00000185651.101361.718001773.47790-0.381205.145304.30040HepG2DNAJC2
    UBE2L3ENSG00000185651.101107.051901951.82020-0.8181010.849609.72340HepG2EIF2S1
    UBE2L3ENSG00000185651.102081.486402691.77750-0.370906.510805.32310HepG2EIF4G1
    UBE2L3ENSG00000185651.101783.436702578.54050-0.531906.289005.08350HepG2EIF4G2
    UBE2L3ENSG00000185651.102239.431802749.56350-0.296104.517603.78410HepG2ETF1
    UBE2L3ENSG00000185651.102134.080701580.911000.432805.098103.96690HepG2EWSR1
    UBE2L3ENSG00000185651.102023.447103306.60000-0.708503.068301.99770HepG2FTO
    UBE2L3ENSG00000185651.101338.716201816.17370-0.440104.879403.85110HepG2FUBP3
    UBE2L3ENSG00000185651.101518.345402018.86570-0.411003.088602.38750HepG2G3BP1
    UBE2L3ENSG00000185651.101902.127801533.201100.311002.078501.30640HepG2GEMIN5
    UBE2L3ENSG00000185651.101270.214701544.60540-0.282203.329302.26340HepG2HDGF
    UBE2L3ENSG00000185651.101453.918802009.27530-0.466705.118204.19740HepG2HNRNPC
    UBE2L3ENSG00000185651.102580.691403259.91010-0.337103.074102.32090HepG2HNRNPF
    UBE2L3ENSG00000185651.101451.696702044.49710-0.494005.192704.25910HepG2HNRNPK
    UBE2L3ENSG00000185651.102000.015902485.33190-0.313405.969205.01190HepG2HNRNPL
    UBE2L3ENSG00000185651.102463.802703571.12490-0.535506.227105.32460HepG2HNRNPLL
    UBE2L3ENSG00000185651.102436.823703210.10240-0.397602.835602.10200HepG2IGF2BP1
    UBE2L3ENSG00000185651.101494.533802064.12300-0.465803.134802.05880HepG2KHSRP
    UBE2L3ENSG00000185651.101143.970601478.93250-0.370506.063804.58110HepG2KIF1C
    UBE2L3ENSG00000185651.102579.337203641.84350-0.497703.232902.18030HepG2MTPAP
    UBE2L3ENSG00000185651.102324.517702705.46640-0.218902.025501.37060HepG2NOL12
    UBE2L3ENSG00000185651.102376.295503166.40550-0.414104.282803.35750HepG2NSUN2
    UBE2L3ENSG00000185651.10718.582301995.55800-1.4736030.7501028.41150HepG2PABPC4
    UBE2L3ENSG00000185651.102337.609201975.671500.242602.957902.08580HepG2PARN
    UBE2L3ENSG00000185651.101480.580001780.26140-0.265902.736402.00270HepG2PPIL4
    UBE2L3ENSG00000185651.101604.278402104.44960-0.391506.274405.51570HepG2PTBP1
    UBE2L3ENSG00000185651.102322.214602741.58890-0.239504.014503.32840HepG2PUM1
    UBE2L3ENSG00000185651.102202.279402739.57320-0.315003.504002.75320HepG2PUM2
    UBE2L3ENSG00000185651.101389.079101647.98320-0.246602.903902.27640HepG2PUS1
    UBE2L3ENSG00000185651.101425.659602279.16910-0.6769013.8215012.57990HepG2QKI
    UBE2L3ENSG00000185651.101338.376102017.22710-0.591903.272402.50820HepG2RAVER1
    UBE2L3ENSG00000185651.103005.942802298.120100.387306.149305.45120HepG2RBM22
    UBE2L3ENSG00000185651.101881.990802342.04970-0.315504.568703.90550HepG2NELFE
    UBE2L3ENSG00000185651.101583.971802181.30230-0.461608.798307.79210HepG2RECQL
    UBE2L3ENSG00000185651.102135.003701681.687900.344202.821501.87320HepG2SERBP1
    UBE2L3ENSG00000185651.102943.899903534.77150-0.263902.074401.45730HepG2SF3B1
    UBE2L3ENSG00000185651.101796.122402191.00220-0.286703.851403.17200HepG2SF3B4
    UBE2L3ENSG00000185651.101845.581502476.37560-0.424209.686308.49950HepG2SLBP
    UBE2L3ENSG00000185651.102438.113902072.862800.234003.831503.09460HepG2SMN1
    UBE2L3ENSG00000185651.103134.411002595.631300.272004.400603.81120HepG2SRFBP1
    UBE2L3ENSG00000185651.102985.285902286.932600.384407.575806.88400HepG2SRSF1
    UBE2L3ENSG00000185651.102221.482702549.98880-0.199002.180701.61770HepG2SRSF5
    UBE2L3ENSG00000185651.102447.902803202.67940-0.387707.186106.14630HepG2SRSF7
    UBE2L3ENSG00000185651.101526.630401860.54200-0.285403.887003.25530HepG2SRSF9
    UBE2L3ENSG00000185651.101400.825402055.58590-0.5533010.090909.12760HepG2TAF15
    UBE2L3ENSG00000185651.102221.071103480.45030-0.648009.682708.44560HepG2TARDBP
    UBE2L3ENSG00000185651.101360.502001888.80160-0.473306.201404.95630HepG2TIA1
    UBE2L3ENSG00000185651.101580.804601956.81830-0.307904.236203.56730HepG2TRIM56
    UBE2L3ENSG00000185651.101874.447302523.14720-0.428805.258004.01380HepG2TUFM
    UBE2L3ENSG00000185651.104172.036503021.196800.465505.498404.63070HepG2U2AF1
    UBE2L3ENSG00000185651.10196.848402670.73420-3.76210142.06670137.98930HepG2UBE2L3
    UBE2L3ENSG00000185651.101105.658602652.11770-1.2622063.4626061.10660HepG2UPF1
    UBE2L3ENSG00000185651.103787.464502560.524200.5647017.3469016.03840HepG2UTP3
    UBE2L3ENSG00000185651.1018117.8431027277.90260-0.590309.568707.34910K562ABCF1
    UBE2L3ENSG00000185651.1014525.9915012739.159700.189303.006902.41850K562AGGF1
    UBE2L3ENSG00000185651.1017790.8343013997.922900.345803.814802.62050K562AKAP8
    UBE2L3ENSG00000185651.1016314.6244013255.553100.299503.017702.33470K562AKAP8L
    UBE2L3ENSG00000185651.1015465.0398012276.522000.333003.439402.79970K562AQR
    UBE2L3ENSG00000185651.106225.700507602.33200-0.288206.166204.71200K562BCLAF1
    UBE2L3ENSG00000185651.1018350.8233015224.384700.269403.240901.94920K562CCDC124
    UBE2L3ENSG00000185651.1013527.5538018090.29770-0.419307.057205.79630K562CPSF6
    UBE2L3ENSG00000185651.104789.181105767.50230-0.268203.686902.44230K562CSTF2
    UBE2L3ENSG00000185651.1017466.9917020683.61300-0.243902.872902.20920K562DDX47
    UBE2L3ENSG00000185651.1019345.4109014264.677300.4394010.423408.50150K562DKC1
    UBE2L3ENSG00000185651.107393.324506504.952900.184602.071801.37540K562EIF3G
    UBE2L3ENSG00000185651.106477.441105083.553900.349505.586303.62710K562EWSR1
    UBE2L3ENSG00000185651.1011564.5076015602.20110-0.432004.455503.27030K562FTO
    UBE2L3ENSG00000185651.106683.371105494.168800.282603.602801.53530K562FUBP3
    UBE2L3ENSG00000185651.1011029.421806056.479700.8647038.1547036.06050K562FXR1
    UBE2L3ENSG00000185651.1013991.5139017271.43560-0.303803.277302.41480K562GPKOW
    UBE2L3ENSG00000185651.105897.139809853.44860-0.7406017.7172016.28770K562HNRNPC
    UBE2L3ENSG00000185651.109934.581307567.300500.392603.793302.32060K562HNRNPK
    UBE2L3ENSG00000185651.1023895.2112016127.391600.567106.698705.15320K562HNRNPM
    UBE2L3ENSG00000185651.1017143.5495014067.875500.285202.854902.01470K562KIF1C
    UBE2L3ENSG00000185651.1011507.6216014748.56100-0.358002.429101.56100K562KRR1
    UBE2L3ENSG00000185651.1013486.0856016858.99490-0.322003.860702.81440K562METAP2
    UBE2L3ENSG00000185651.1011766.6618014181.33320-0.269303.374902.48550K562MTPAP
    UBE2L3ENSG00000185651.1015484.6749011046.241900.487203.993502.87740K562NAA15
    UBE2L3ENSG00000185651.107447.651705815.410500.356805.202703.52000K562NCBP2
    UBE2L3ENSG00000185651.1012387.9337015757.79970-0.347105.207104.22950K562NSUN2
    UBE2L3ENSG00000185651.109887.937006250.770300.6615011.222209.70260K562PRPF8
    UBE2L3ENSG00000185651.1010154.745407736.560600.392305.651104.73130K562PTBP1
    UBE2L3ENSG00000185651.1020869.9330013146.731000.6666011.9518010.87110K562PUS1
    UBE2L3ENSG00000185651.1018883.7450012808.796400.5599014.9088013.51780K562RBM15
    UBE2L3ENSG00000185651.108221.200006500.715400.338702.814101.47350K562RBM25
    UBE2L3ENSG00000185651.1013816.0328011320.915700.287303.186902.02600K562SAFB
    UBE2L3ENSG00000185651.1015894.882808911.205800.834802.384001.30220K562SF1
    UBE2L3ENSG00000185651.109515.1944015547.34280-0.7084014.4852012.73050K562SF3A3
    UBE2L3ENSG00000185651.108778.934407126.463000.300803.827802.81680K562SF3B4
    UBE2L3ENSG00000185651.1018629.2307010239.968200.863302.613701.43250K562SNRNP200
    UBE2L3ENSG00000185651.1010441.639107584.464200.461107.811906.63090K562SRSF1
    UBE2L3ENSG00000185651.1018845.0235012743.499400.564303.279102.38570K562SYNCRIP
    UBE2L3ENSG00000185651.1017201.7985022938.65180-0.415204.608402.69270K562TRIP6
    UBE2L3ENSG00000185651.109958.433306643.445600.583906.624604.78430K562U2AF1
    UBE2L3ENSG00000185651.109696.219506860.945800.498909.651708.15020K562U2AF2
    UBE2L3ENSG00000185651.104012.9801023482.03340-2.5488054.2408049.81460K562UBE2L3
    UBE2L3ENSG00000185651.1010767.6744014296.85480-0.409005.067703.86620K562WDR3
    UBE2L3ENSG00000185651.1010710.9752013830.74630-0.368804.451003.31520K562ZC3H8
    Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

    *: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
    **: "-log(0)" was displayed as "99999.99999".






    The Knockdown/knockout RNA-Seq assay for UBE2L3 is not available on ENCORE database.





    9 RBPs can affect the splicing of UBE2L3 :

    Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
    SEUBE2L3ENSG00000185651.10chr22+219471492194720021921835219220602196514521965332-0.438000.000000.00000excludedK562SF3B4
    SEUBE2L3ENSG00000185651.10chr22+219471492194720021921835219220602196514521965332-0.272000.000370.01739excludedK562PRPF8
    SEUBE2L3ENSG00000185651.10chr22+219471492194724521921835219220602196514521965332-0.072000.000000.00000excludedHepG2PRPF8
    SEUBE2L3ENSG00000185651.10chr22+2194705021947200219220252192206021965145219653320.131000.007150.06223includedK562AQR
    SEUBE2L3ENSG00000185651.10chr22+219471492194728921921835219220602196514521965332-0.078000.000000.00000excludedK562AQR
    SEUBE2L3ENSG00000185651.10chr22+219471492194720021921835219220602196514521965332-0.292000.001990.06623excludedK562FXR1
    SEUBE2L3ENSG00000185651.10chr22+219471492194722621921835219220602196514521965332-0.187000.000000.00000excludedK562PUS1
    SEUBE2L3ENSG00000185651.10chr22+219471492194724521921835219220602196514521965332-0.079000.000000.00000excludedHepG2PCBP2
    SEUBE2L3ENSG00000185651.10chr22+2194714921947200219218352192206021965145219653320.346000.000000.00000includedK562HNRNPM
    SEUBE2L3ENSG00000185651.10chr22+219471492194728921921835219220602196514521965332-0.137000.000000.00000excludedHepG2SF3A3
    SEUBE2L3ENSG00000185651.10chr22+219471492194728921921835219220602196514521965332-0.136000.000000.00000excludedK562SF3B1

    *: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
    **: "-log(0)" was displayed as "99999.99999".





    The Knockdown/knockout RNA-Seq assay for UBE2L3 is not avaliable on ENCORE database.