TTC27

General Information

Gene Name       : TTC27
Gene ID             : ENSG00000018699.12
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: TTC27)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878TTC27ENSG00000018699.1226.9721.5024.23ENCSR000AEF
HepG2TTC27ENSG00000018699.1220.2233.2126.71ENCSR985KAT
K562TTC27ENSG00000018699.1246.2253.8150.02ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for TTC27 is not avaliable on ENCORE database.



Proteins bound to RNA
  • TTC27 RNA is bound by 13 proteins.  







eCLIP assay for TTC27 is not avaliable on ENCORE database.





13 proteins are bound to TTC27 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr23301217333012216+3'-UTR,5'-UTR,CDS4.014124.31428K562YBX3
chr23299153532991598+3'-UTR,CDS,intron-Distal3.809023.16028HepG2SUGP2
chr23303628433036398+3'-UTR,CDS,intron-Distal,intron-Proximal3.694063.26999K562KHSRP
chr23295897132958989+3'-UTR,CDS4.580344.70478HepG2BCLAF1
chr23292789932927935+3'-UTR,CDS3.636073.12746HepG2GRWD1
chr23290395632903989+5'-UTR,CDS3.790953.22721K562YBX3
chr23285313532853207+5'-UTR,intron-Proximal3.593744.84938K562DDX3X
chr23285569232855765+CDS,intron-Distal5.007138.32277K562LIN28B
chr23285894232858988+CDS,intron-Distal,intron-Proximal4.3193610.57092HepG2BCLAF1
chr23285567432855718+CDS,intron-Distal5.130116.13315HepG2BCLAF1
chr23285569032855735+CDS,intron-Distal4.345844.10264K562ZNF622
chr23286544932865475+CDS,intron-Distal4.859826.13315HepG2BCLAF1
chr23285572332855765+CDS,intron-Distal5.395028.86847HepG2BCLAF1
chr23287526032875294+CDS,intron-Distal3.381365.00751HepG2BCLAF1
chr23286534732865381+CDS,intron-Distal3.498595.97823HepG2BCLAF1
chr23298619532986322+intron-Distal3.893323.31570HepG2HNRNPK
chr23298619332986263+intron-Distal3.883675.38389HepG2PCBP2
chr23300628533006357+intron-Distal4.517194.17759HepG2QKI
chr23298621232986338+intron-Distal3.886633.11802K562HNRNPK
chr23294884032948883+intron-Distal3.450823.62418K562PTBP1
chr23300627533006366+intron-Distal5.233566.85401K562QKI
chr23294881632948918+intron-Distal4.138467.54289HepG2PTBP1
chr23294888332948927+intron-Distal4.833595.81225K562PTBP1
chr23301331033013375+intron-Distal3.397973.51804HepG2HNRNPL
chr23297628732976360+intron-Distal3.016723.17661HepG2HNRNPL
chr23286551532865664+intron-Distal,intron-Proximal3.927823.92684K562KHSRP
chr23295260432952679+intron-Distal4.008313.16986HepG2QKI
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for TTC27 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for TTC27 is not available on ENCORE database.

  • 97 RBPs can affect the levels of TTC27.  








The Knockdown/knockout RNA-Seq assay for TTC27 is not available on ENCORE database.





97 RBPs can affect the gene expression of TTC27 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
TTC27ENSG00000018699.71562.781801229.334400.346102.025401.56250HepG2AKAP1
TTC27ENSG00000018699.7422.29740673.19110-0.672805.143603.95400HepG2BCLAF1
TTC27ENSG00000018699.7454.72120617.34520-0.441102.813901.57110HepG2BUD13
TTC27ENSG00000018699.7808.52160579.630500.480102.157601.48740HepG2CNOT7
TTC27ENSG00000018699.7424.85340759.07430-0.837309.877008.67910HepG2DDX21
TTC27ENSG00000018699.7590.063001011.60470-0.777707.188906.23260HepG2DDX6
TTC27ENSG00000018699.7531.21030668.22340-0.331002.538601.88660HepG2DKC1
TTC27ENSG00000018699.7524.35940669.21070-0.351903.364202.65790HepG2DNAJC2
TTC27ENSG00000018699.7542.38430972.45840-0.842309.076708.04100HepG2EIF2S1
TTC27ENSG00000018699.7720.597301074.67030-0.576604.366903.56800HepG2EIF4A3
TTC27ENSG00000018699.7803.979301094.22940-0.444703.894602.93840HepG2EIF4G2
TTC27ENSG00000018699.71092.156201388.20430-0.346004.457703.72770HepG2ETF1
TTC27ENSG00000018699.7847.023301084.32920-0.356302.244101.61880HepG2FXR1
TTC27ENSG00000018699.7669.337501005.85750-0.587604.792403.92780HepG2G3BP1
TTC27ENSG00000018699.7774.229301067.86860-0.463903.536802.52360HepG2G3BP2
TTC27ENSG00000018699.7535.40680721.16860-0.429702.666801.66890HepG2GNB2L1
TTC27ENSG00000018699.7529.92790762.87810-0.525703.449102.74000HepG2GPKOW
TTC27ENSG00000018699.7274.27970758.23770-1.4670023.7394021.93700HepG2HNRNPC
TTC27ENSG00000018699.7710.27770943.11040-0.409004.348003.47150HepG2HNRNPF
TTC27ENSG00000018699.7855.645001054.87010-0.302003.765702.98640HepG2HNRNPL
TTC27ENSG00000018699.7520.54930728.02590-0.484003.254702.57870HepG2HNRNPLL
TTC27ENSG00000018699.7512.08040753.22580-0.556706.920705.99950HepG2HNRNPU
TTC27ENSG00000018699.7649.00900928.70090-0.517005.285304.31710HepG2IGF2BP1
TTC27ENSG00000018699.7729.932501022.42620-0.486203.686502.91580HepG2IGF2BP2
TTC27ENSG00000018699.7762.618001028.39720-0.431402.388501.46760HepG2KHSRP
TTC27ENSG00000018699.7895.918901167.88070-0.382502.120301.40120HepG2LARP4
TTC27ENSG00000018699.7652.614501084.70790-0.733007.437606.37570HepG2MAGOH
TTC27ENSG00000018699.7474.45650673.41610-0.505203.780202.83780HepG2MSI2
TTC27ENSG00000018699.7533.68930742.42810-0.476302.231801.36770HepG2MTPAP
TTC27ENSG00000018699.7731.500601148.22490-0.6505010.146908.71990HepG2NOL12
TTC27ENSG00000018699.7479.26100645.51310-0.429602.603001.87580HepG2NSUN2
TTC27ENSG00000018699.7564.24200818.16960-0.536102.971401.89650HepG2PCBP2
TTC27ENSG00000018699.7720.851301028.42320-0.512706.953206.16480HepG2PTBP1
TTC27ENSG00000018699.7649.381801096.03200-0.7552010.505109.44420HepG2PUF60
TTC27ENSG00000018699.71018.165901163.42870-0.192402.077001.54810HepG2PUM1
TTC27ENSG00000018699.7924.112801162.61470-0.331203.128202.41600HepG2PUM2
TTC27ENSG00000018699.7554.39250711.41940-0.359803.399202.73440HepG2PUS1
TTC27ENSG00000018699.7829.519401113.82900-0.425204.497303.72800HepG2QKI
TTC27ENSG00000018699.7767.332501010.86340-0.397703.431302.68670HepG2RBM25
TTC27ENSG00000018699.7842.096601144.54460-0.442705.561904.83730HepG2NELFE
TTC27ENSG00000018699.7878.802601065.97260-0.278602.585101.98630HepG2RECQL
TTC27ENSG00000018699.7749.656701015.86530-0.438403.446902.69770HepG2RPLP0
TTC27ENSG00000018699.7503.18230775.54860-0.624103.618102.53820HepG2RPS10
TTC27ENSG00000018699.7366.42330529.20050-0.530303.810503.09960HepG2RPS19
TTC27ENSG00000018699.7603.11280785.71170-0.381602.352701.61030HepG2RPS2
TTC27ENSG00000018699.7699.323801070.73920-0.614609.605408.60300HepG2SF3B4
TTC27ENSG00000018699.7884.235601050.80540-0.249002.667401.97590HepG2SLBP
TTC27ENSG00000018699.7497.53400801.80860-0.688504.042703.08970HepG2SNRNP70
TTC27ENSG00000018699.71296.598801117.612600.214201.872601.46200HepG2SRSF1
TTC27ENSG00000018699.7739.035501082.10280-0.550108.681707.65410HepG2SRSF5
TTC27ENSG00000018699.7633.43680926.55280-0.548707.216406.17490HepG2SRSF7
TTC27ENSG00000018699.7738.16240909.23110-0.300702.885202.32440HepG2SRSF9
TTC27ENSG00000018699.7903.631801137.77990-0.332403.859903.27680HepG2SSB
TTC27ENSG00000018699.71018.268601230.70820-0.273403.428002.74970HepG2SUCLG1
TTC27ENSG00000018699.7569.61110758.30970-0.412802.283001.66090HepG2SUPV3L1
TTC27ENSG00000018699.7558.40240709.52250-0.345501.983101.35660HepG2TARDBP
TTC27ENSG00000018699.7309.91350731.95980-1.2399021.9383020.78030HepG2TIAL1
TTC27ENSG00000018699.7489.50730738.43840-0.593107.874607.00160HepG2TRIM56
TTC27ENSG00000018699.7778.187701070.68270-0.460304.695403.52340HepG2TUFM
TTC27ENSG00000018699.7789.773801133.23880-0.520904.100203.07140HepG2UBE2L3
TTC27ENSG00000018699.7506.48180696.51070-0.459604.904204.01690HepG2UPF1
TTC27ENSG00000018699.7849.83570672.450800.337703.047502.42420HepG2UTP3
TTC27ENSG00000018699.7547.72220746.47320-0.446602.853602.11810HepG2XRN2
TTC27ENSG00000018699.71000.626002233.93050-1.1587024.5866023.02670K562AQR
TTC27ENSG00000018699.71178.185201435.55950-0.285002.803501.48400K562BCCIP
TTC27ENSG00000018699.71018.565901387.21870-0.445706.668005.14610K562BCLAF1
TTC27ENSG00000018699.7709.76080943.51440-0.410702.924302.03020K562BOP1
TTC27ENSG00000018699.71070.342701470.93600-0.458703.624501.95000K562BUD13
TTC27ENSG00000018699.7424.56410599.89990-0.498703.415502.21930K562CCAR1
TTC27ENSG00000018699.7696.410101003.23260-0.526605.423304.33300K562CPSF6
TTC27ENSG00000018699.72342.617301952.655500.262603.446302.72980K562DDX47
TTC27ENSG00000018699.71527.140701277.226000.257702.185001.41730K562DKC1
TTC27ENSG00000018699.7782.590601177.58030-0.589505.723104.38100K562EFTUD2
TTC27ENSG00000018699.7828.774801086.94270-0.391204.583303.00130K562EIF2S1
TTC27ENSG00000018699.71142.280001719.98960-0.5905010.878509.59650K562EIF2S2
TTC27ENSG00000018699.71269.91260997.400500.348403.441502.56000K562EIF3G
TTC27ENSG00000018699.7684.528001033.84810-0.594806.403605.16230K562EIF4A3
TTC27ENSG00000018699.7737.32290931.03290-0.336502.995901.77970K562EIF4B
TTC27ENSG00000018699.7689.22640902.44180-0.388903.283601.85130K562EWSR1
TTC27ENSG00000018699.71100.694401518.01910-0.463804.520503.41710K562FIP1L1
TTC27ENSG00000018699.7652.057201020.75370-0.646606.617105.27320K562FMR1
TTC27ENSG00000018699.7619.73240865.17580-0.481303.547302.50210K562FTO
TTC27ENSG00000018699.71363.228901075.157900.342403.840903.14510K562FXR1
TTC27ENSG00000018699.7714.08800957.84500-0.423703.396602.51930K562GPKOW
TTC27ENSG00000018699.71733.107702292.18350-0.403404.404803.45610K562GRSF1
TTC27ENSG00000018699.71225.411701560.04990-0.348303.367202.17870K562HNRNPA1
TTC27ENSG00000018699.7196.190801153.88550-2.5562079.1649076.08220K562HNRNPC
TTC27ENSG00000018699.7669.468301030.42560-0.622206.854104.97730K562HNRNPF
TTC27ENSG00000018699.71458.229401727.59910-0.244602.302701.48550K562HNRNPU
TTC27ENSG00000018699.71006.092201362.99770-0.438002.994601.91340K562IGF2BP2
TTC27ENSG00000018699.7746.47140934.96160-0.324802.262701.47190K562METAP2
TTC27ENSG00000018699.72048.639202746.77400-0.423104.026402.66440K562MSI2
TTC27ENSG00000018699.71046.662601416.47710-0.436506.701105.49290K562MTPAP
TTC27ENSG00000018699.71328.075501573.84280-0.245003.374402.55820K562NSUN2
TTC27ENSG00000018699.7843.768101265.47020-0.584805.341904.18250K562PCBP3
TTC27ENSG00000018699.7686.42410970.65930-0.499905.133304.04100K562POLR2G
TTC27ENSG00000018699.7703.583401034.58040-0.556305.383104.06670K562PSIP1
TTC27ENSG00000018699.72380.204702930.22510-0.299903.614602.51740K562PUM2
TTC27ENSG00000018699.7983.456301334.80090-0.440704.085703.04320K562RBM22
TTC27ENSG00000018699.7646.877501038.01580-0.682308.679606.15720K562RBM25
TTC27ENSG00000018699.7632.83760943.92640-0.576806.363804.86440K562RCC2
TTC27ENSG00000018699.71176.989601552.96710-0.399905.215404.12120K562SF3A3
TTC27ENSG00000018699.7835.821201137.91970-0.445104.840703.69600K562SF3B4
TTC27ENSG00000018699.7645.82520894.81640-0.470403.736502.49370K562SRFBP1
TTC27ENSG00000018699.71003.298601364.51810-0.443604.732203.81160K562SRSF1
TTC27ENSG00000018699.7923.737101288.62410-0.480304.566403.15950K562SRSF5
TTC27ENSG00000018699.7652.093401109.70560-0.767007.666505.91760K562SUPV3L1
TTC27ENSG00000018699.71408.57070973.595900.532706.991405.66940K562SYNCRIP
TTC27ENSG00000018699.7920.941601381.03400-0.584606.149905.06040K562TARDBP
TTC27ENSG00000018699.71001.270801332.14940-0.411904.177903.14040K562TIA1
TTC27ENSG00000018699.7571.56300995.09260-0.799908.564306.84630K562TIAL1
TTC27ENSG00000018699.7970.733601307.11020-0.429203.886502.55930K562TRA2A
TTC27ENSG00000018699.7747.446101057.16380-0.500204.571203.28410K562TRIM56
TTC27ENSG00000018699.71404.964201885.30230-0.424307.441905.31040K562TROVE2
TTC27ENSG00000018699.7760.700701060.81050-0.479803.440002.19400K562U2AF1
TTC27ENSG00000018699.7582.727801095.50860-0.9107016.1500014.18030K562U2AF2
TTC27ENSG00000018699.7711.746601174.38150-0.722507.869906.08050K562UCHL5
TTC27ENSG00000018699.71108.340801668.77820-0.5904012.5959011.20060K562UPF1
TTC27ENSG00000018699.7453.774701427.92200-1.6539047.5935044.47530K562WDR3
TTC27ENSG00000018699.72002.612702646.52100-0.402204.696903.00790K562WRN
TTC27ENSG00000018699.7894.657401195.68280-0.418403.047801.75840K562XRN2
TTC27ENSG00000018699.71609.740002516.73220-0.644709.870008.12280K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for TTC27 is not available on ENCORE database.





7 RBPs can affect the splicing of TTC27 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SETTC27ENSG00000018699.7chr2+3300512033005179330029483300304733007692330077450.064000.000430.06588includedK562MATR3
SETTC27ENSG00000018699.7chr2+3300512033005179330029483300304733007692330077450.067000.000180.04882includedK562PCBP1
SETTC27ENSG00000018699.7chr2+330375703303768233012050330122163304252333042624-0.129000.000000.00003excludedK562AQR
SETTC27ENSG00000018699.7chr2+328916543289183532889369328895343289733832897451-0.066000.012810.09868excludedK562AQR
SETTC27ENSG00000018699.7chr2+3300294833003047329833583298358633007692330077450.084000.003330.06467includedHepG2SRSF1
SETTC27ENSG00000018699.7chr2+329617603296188332958894329589903298335832983586-0.100000.004980.07231excludedK562U2AF2
SETTC27ENSG00000018699.7chr2+3300512033005179330029483300304733007692330077450.065000.000350.01644includedK562TARDBP
A5SSTTC27ENSG00000018699.7chr2+3285309832853244328530983285320032855589328557200.657000.000020.01003longerK562DROSHA

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for TTC27 is not avaliable on ENCORE database.