XRN2

General Information

Gene Name       : XRN2
Gene ID             : ENSG00000088930.7
Essential Gene : Yes

Functions

Localization(RBPImage: XRN2)

Domains (AlphaFold: XRN2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878XRN2ENSG00000088930.767.3961.9464.66ENCSR000AEF
HepG2XRN2ENSG00000088930.786.49121.53104.01ENCSR985KAT
K562XRN2ENSG00000088930.739.8142.1740.99ENCSR000AEO

Assays

5 Released experiments are available on ENCORE database.

Assay TypeExp_NameENCODE IDTarget labelBiosampleStatusLinked AntibodyControlsMethodNote
eCLIPeCLIP: 245ENCSR657TZBXRN2K562ReleasedENCAB995BMTENCSR170XQH  
eCLIPeCLIP: 235ENCSR655NZAXRN2HepG2ReleasedENCAB995BMTENCSR247PDK  
knockdown followed by RNA-seq XRN2-BGKLV19-K562ENCSR717SJAXRN2K562ReleasedENCSR661HEL   shRNAKD% = 59.1,64.2
knockdown followed by RNA-seq XRN2-BGHLV17-HepG2ENCSR347ZHQXRN2HepG2ReleasedENCSR856ZRV   shRNAKD% = 99.7,99.7
RNA Bind-n-SeqRBNS: XRN2XRN2cell-free sampleReleased






  eCLIP  
  RBP    Exp_UID    Cell_Line    ENCODE_ACCESSION    Control_ENCODE_ACCESSION    ENCODE_Antibody_ID    Antibody    Lot_num    Status    Project  
XRN2245K562ENCSR657TZBENCSR170XQHENCAB995BMTA301-103A1ReleasedENCODE3
XRN2235HepG2ENCSR655NZAENCSR247PDKENCAB995BMTA301-103A1ReleasedENCODE3


  Antibody Validation  
  GeneName    Antibody_DCC_ID    Product_ID    Lot_ID    Phosphate    HepG2 Primary Validation    K562 Primary Validation    HepG2 Secondary Validation    K562 Secondary Validation  
XRN2ENCAB995BMTA301-103A1Released, ENCODE3Released, ENCODE3BGHLV17-41, Released, ENCODE3BGKLV19-63, Released, ENCODE3


  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
XRN2K562shRNAENCSR717SJAENCSR661HELXRN2_BGKLV19_63B,XRN2_BGKLV19_64BNT_BGKLV19_1B,NT_BGKLV19_2B59.1,64.2ReleasedENCODE3
XRN2HepG2shRNAENCSR347ZHQENCSR856ZRVXRN2_BGHLV17_41,XRN2_BGHLV17_42NT_BGHLV17_63,NT_BGHLV17_6499.7,99.7ReleasedENCODE3


  RNA Bind-n-Seqn  
  GeneName    gene_aliases    Status    Project    Note  
XRN2XRN2ReleasedENCODE4


  Localization Image in HepG2  
    XRN2: Click to RBP Image Database
  • Nuclei
  • Nucleoplasm
  • Mutually Exclusive from Nucleolus
  • Speckles
  • Nuclear release mitosis












    • RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela
    XRN2Product_ID: A301-103A
    Lot_ID: 1
    Source: Bethyl Labs
    Target Name: XRN2-human    		 HepG2_Bethyl_A301-103A_1_XRN2.png<br>Caption: IP-Western Blot analysis of HepG2 whole cell lysate using XRN2 specific antibody. Lane 1 is 1% of twenty million whole cell lysate input and lane 2 is 25% of IP enrichment using rabbit normal IgG (lanes under 'IgG'). Lane 3 is 1% of twenty million whole cell lysate input and lane 4 is 10% IP enrichment using rabbit polyclonal anti-XRN2 antibody (lanes under 'XRN2').
    		 XRN2_Secondary_Western.png<br>Caption: Western blot following shRNA against XRN2 in K562 and HepG2 whole cell lysate using XRN2 specific antibody. Lane 1 is a ladder, lane 2 is K562 non-targeting control knockdown, lane 2 and 3 are two different shRNAs against XRN2. Lanes 5-7 follow the same pattern, but in HepG2. XRN2 protein appears as the green band, GAPDH serves as a control and appears in red.
    		 K562_Bethyl_A301-103A_1_XRN2.png<br>Caption: IP-Western Blot analysis of K562 whole cell lysate using XRN2 specific antibody. Lane 1 is 1% of twenty million whole cell lysate input and lane 2 is 25% of IP enrichment using rabbit normal IgG (lanes under 'IgG'). Lane 3 is 1% of twenty million whole cell lysate input and lane 4 is 10% IP enrichment using rabbit polyclonal anti-XRN2 antibody (lanes under 'XRN2').
    		 XRN2_Secondary_Western.png<br>Caption: Western blot following shRNA against XRN2 in K562 and HepG2 whole cell lysate using XRN2 specific antibody. Lane 1 is a ladder, lane 2 is K562 non-targeting control knockdown, lane 2 and 3 are two different shRNAs against XRN2. Lanes 5-7 follow the same pattern, but in HepG2. XRN2 protein appears as the green band, GAPDH serves as a control and appears in red.








    RNA Targets
    • XRN2 protein binds to 3,142 RNA regions.  




    • The binding motifs of XRN2

      • Trulli

    Proteins bound to RNA
    • XRN2 RNA is bound by 37 proteins.  






    XRN2 protein has 3,142 RNA targets:

    Only display 100 entries as example. Please click "View All" button to see all 3,142 entries.     

    RBP Chr Start End Strand log2(fold change) -log(p-value) Cell Line Matched Gene Matched Area
    XRN2chr1628193922819421+4.1509523.29343K562SRRM2intron-Distal
    XRN2chr125384645553846533+3.9210610.61112HepG2RP11-793H13.8, PCBP2intron-Distal
    XRN2chr7148580625148580697-3.383377.85614K562EZH2intron-Distal,intron-Proximal
    XRN2chr26176447061764497-4.698965.49785HepG2XPO1intron-Distal
    XRN2chr9139565726139565796+3.270076.23800K562EGFL7intron-Distal
    XRN2chr1625812652581329+3.108915.90306HepG2AMDHD23'-UTR
    XRN2chr77515712275157204-3.520033.19036K562PMS2P3intron-Distal,intron-Proximal
    XRN2chr8141645017141645104-4.787484.93963HepG2AGO2intron-Distal
    XRN2chr12921692329217033+3.316323.94795K562EPB41intron-Distal
    XRN2chr1646601944660217-4.581734.33932HepG2UBALD1CDS,intron-Distal
    XRN2chr174597381145973873+4.388223.17453HepG2SP2intron-Distal
    XRN2chr417964361796492+4.1484810.42504HepG2FGFR3intron-Distal
    XRN2chr4982093982146-3.206934.64240HepG2SLC26A13'-UTR,intron-Distal
    XRN2chrX152909596152909642+3.888224.64240HepG2DUSP9intron-Distal
    XRN2chr82892150428921605+5.286289.14026K562HMBOX1intron-Distal,intron-Proximal
    XRN2chr2242499638242499681+3.745523.29596HepG2BOKintron-Distal
    XRN2chr1185014844185014958+3.323875.31614K562RNF2intron-Distal,intron-Proximal
    XRN2chr1270370867037269+3.303397.03728K562ATN1intron-Distal
    XRN2chr214682559846825654+4.350975.02437HepG2COL18A1intron-Distal
    XRN2chr173686200536862081+3.485654.97257HepG2MLLT6intron-Proximal
    XRN2chr116563122365631276+3.040354.92883K562MUS81CDS,intron-Proximal
    XRN2chr63664679336646827+3.038004.83012HepG2CDKN1Aintron-Distal,intron-Proximal
    XRN2chr9139558118139558188+3.690555.12149K562EGFL7intron-Distal,intron-Proximal
    XRN2chr13111566812111566900-3.993804.96235K562ANKRD10intron-Distal
    XRN2chrX153628987153629017+3.1126717.93659K562RPL10intron-Distal,intron-Proximal
    XRN2chr225064003450640095+3.182753.65183HepG2SELOintron-Proximal
    XRN2chr26176458661764662-3.884068.33793HepG2XPO1intron-Distal,intron-Proximal
    XRN2chr168879832588798366-5.209903.56577HepG2PIEZO1intron-Distal,intron-Proximal
    XRN2chr116822850468228565+3.736513.19036K562PPP6R3intron-Distal
    XRN2chr6151187565151187649+4.825456.05963HepG2MTHFD1L5'-UTR,intron-Distal
    XRN2chr11485537485687+6.3753917.57917K562PTDSS2intron-Distal
    XRN2chr162455123624551281+4.053597.36479K562RBBP6intron-Distal
    XRN2chr203117183831171896-3.509655.04221K562C20orf112intron-Distal
    XRN2chr34847061048470674-3.678646.26243HepG2PLXNB15'-UTR,intron-Distal
    XRN2chr3186502208186502218+4.3136850.01747K562EIF4A25'-UTR,intron-Proximal
    XRN2chr2132259201132259255+4.791604.86913K562AC093838.4intron-Distal
    XRN2chr72516473125164814-3.493804.34492K562CYCS5'-UTR,intron-Distal
    XRN2chr1920500592050119-3.996776.45904HepG2MKNK2intron-Distal
    XRN2chr106253840562538502+4.579355.45513K562CDK15'-UTR,intron-Distal,intron-Proximal
    XRN2chr19807343807412+3.113405.12778K562PTBP1intron-Distal
    XRN2chr173984580039845893+3.651556.78049K562EIF1intron-Distal
    XRN2chr143254664732546694+3.200744.11052HepG2ARHGAP5intron-Distal,intron-Proximal
    XRN2chr4899181899290-3.392635.31614K562GAKintron-Distal
    XRN2chr7856676856729+4.849344.86913K562SUN1intron-Distal
    XRN2chr2134878469134878518+3.568515.28966HepG2MGAT5intron-Distal
    XRN2chr223991680439916868+3.375198.61484K562ATF45'-UTR,intron-Distal,intron-Proximal
    XRN2chr103324682433246934-3.575123.40600K562ITGB1intron-Distal,intron-Proximal
    XRN2chr191548415815484225-4.228413.02828HepG2AKAP8intron-Distal,intron-Proximal
    XRN2chr194275780042757856-3.318368.99187HepG2AC006486.9, ERFintron-Distal
    XRN2chr9127533267127533348-3.775514.66361K562NR6A1CDS,intron-Distal
    XRN2chr8144873612144873663-3.408843.77433K562SCRIBintron-Distal,intron-Proximal
    XRN2chr12702283127022935+3.1652511.54693K562ARID1A5'-UTR,CDS
    XRN2chr177965395479654021+3.745524.76031HepG2HGSintron-Proximal
    XRN2chr166797711867977171-3.131168.80574HepG2LCAT5'-UTR,intron-Distal,intron-Proximal
    XRN2chr4174254934174255002-3.371137.82667K562HMGB2intron-Distal
    XRN2chr29753466497534695-4.492465.56169K562SEMA4Cintron-Distal
    XRN2chr1245026567245026630-3.132835.80140HepG2HNRNPUintron-Distal
    XRN2chr172636893226368999+3.402803.19036K562NLKintron-Distal
    XRN2chr1912715061271567+3.359875.89769K562CIRBP3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal
    XRN2chr11129871952129872064-3.200896.60422HepG2PRDM10intron-Distal
    XRN2chr122834358128343737+4.230767.94890K562CCDC91intron-Distal,intron-Proximal
    XRN2chr754599915460021-3.414456.32106HepG2TNRC18intron-Distal
    XRN2chr1155947908155947998-3.946895.56169K562ARHGEF25'-UTR,intron-Distal,intron-Proximal
    XRN2chr116401085364010933+3.736514.36583K562FKBP2CDS,intron-Proximal
    XRN2chr7107531729107531833+4.035333.31384K562DLD5'-UTR,CDS,intron-Proximal
    XRN2chr157836994278369959-5.630108.86104HepG2TBC1D2BCDS,intron-Distal
    XRN2chr3180630795180630909+4.471125.77834HepG2FXR1intron-Distal
    XRN2chr64275047342750539+3.353325.46815K562GLTSCR1Lintron-Distal
    XRN2chr7150783464150783517+3.286875.12149K562AGAP3intron-Distal
    XRN2chr19810656810688+3.740324.96235K562PTBP1intron-Proximal
    XRN2chr7150823081150823203+4.832834.54675K562AGAP3intron-Distal
    XRN2chr206071895960719060+4.2427010.03671HepG2SS18L1intron-Distal,intron-Proximal
    XRN2chr11432574432628-3.075123.40600K562ANO9intron-Distal
    XRN2chr1911047011104771+3.095745.47110HepG2GPX45'-UTR,CDS,intron-Distal
    XRN2chr214439529944395365+5.515104.63331HepG2PKNOX1intron-Distal
    XRN2chr116532525065325331-3.397049.87563HepG2LTBP3CDS,intron-Distal,intron-Proximal
    XRN2chr125384644453846524+3.7184310.14836K562RP11-793H13.8, PCBP2intron-Distal
    XRN2chr203436002834360089+3.010783.46665HepG2PHF20intron-Proximal
    XRN2chr714974701497531-4.660095.83649K562MICALL2intron-Distal
    XRN2chr6158244700158244751+4.625195.77834HepG2SNX9intron-Distal
    XRN2chr172713935127139544-3.477598.25655K562FAM222B5'-UTR,intron-Distal,intron-Proximal
    XRN2chr163096930830969438+3.555233.99165K562SETD1Aintron-Distal,intron-Proximal
    XRN2chr194275735142757386-3.245525.65000HepG2AC006486.9, ERFintron-Distal
    XRN2chr168872900088729010-4.201326.16184K562MVDintron-Distal
    XRN2chr162201980822019914+3.879694.39210HepG2C16orf52intron-Distal,intron-Proximal
    XRN2chr1922701682270210+3.973184.89423HepG2OAZ1intron-Distal
    XRN2chr195615056356150606+3.108214.97257HepG2ZNF581, ZNF580intron-Distal
    XRN2chr168460656846160+5.471126.71058HepG2CAMTA1intron-Distal
    XRN2chr19912597912673-4.308634.49762HepG2R3HDM4intron-Distal
    XRN2chr34124126941241358+3.952574.06931K562CTNNB1intron-Distal
    XRN2chr13114144663114144764-3.471124.39210HepG2DCUN1D25'-UTR,CDS,intron-Distal
    XRN2chrX7076701370767041+4.3176511.86196K562OGTintron-Distal
    XRN2chr143254645732546521+4.040353.02324K562ARHGAP55'-UTR,intron-Distal
    XRN2chr174042802340428099-4.432498.53479K562STAT5Bintron-Distal
    XRN2chr15487132354871406-3.483033.19036K562SSBP3intron-Distal
    XRN2chr116822857868228691+3.616358.06895K562PPP6R3intron-Distal
    XRN2chr193920503539205117+3.038123.40600K562ACTN4CDS,intron-Distal,intron-Proximal
    XRN2chr14105933453105933517+3.662916.87801K562MTA1intron-Distal
    XRN2chr162151360621513695-4.0160317.56762HepG2CTD-2547E10.2intron-Distal
    XRN2chr1628030862803143+3.175206.78049K562SRRM2intron-Distal




    37 proteins are bound to XRN2 RNA:

    Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
    chr202137006721370161+3'-UTR4.7425318.87332K562PUM2
    chr202137007621370171+3'-UTR6.1715310.21115HepG2SUB1
    chr202137004121370145+3'-UTR4.461414.51210K562NOLC1
    chr202130700221307043+5'-UTR,CDS,intron-Distal,intron-Proximal3.387937.47194HepG2GRWD1
    chr202128444621284526+5'-UTR,intron-Distal,intron-Proximal3.373053.76326HepG2RBFOX2
    chr202128442621284469+5'-UTR,intron-Distal3.156614.97937HepG2HNRNPM
    chr202128408021284111+5'-UTR,CDS3.250246.63825HepG2GRWD1
    chr202128399021284102+5'-UTR,CDS3.270924.32211K562DDX3X
    chr202130691621306932+5'-UTR,CDS,intron-Distal,intron-Proximal3.989103.83925K562YBX3
    chr202128398921284040+5'-UTR,CDS3.375944.09778HepG2NCBP2
    chr202128410421284111+5'-UTR,CDS3.767293.22721K562YBX3
    chr202128408221284103+5'-UTR,CDS4.309785.20509K562YBX3
    chr202131450521314592+CDS,intron-Proximal5.7404927.50614HepG2EFTUD2
    chr202131967221319729+CDS,intron-Proximal3.6567410.57818HepG2AQR
    chr202131131621311363+CDS,intron-Proximal5.0339310.09745HepG2PRPF8
    chr202133009121330098+CDS3.066616.39923HepG2BCLAF1
    chr202131244321312451+CDS3.155057.61291HepG2BCLAF1
    chr202130921421309297+CDS4.471743.63055K562ZNF800
    chr202131303421313064+CDS3.5451410.11361HepG2BCLAF1
    chr202132476221324799+CDS3.305778.73356HepG2GRWD1
    chr202131109321311171+CDS,intron-Proximal3.910687.50982HepG2AQR
    chr202131420021314254+CDS3.865623.54620HepG2LIN28B
    chr202132712921327177+CDS3.711478.31280HepG2GRWD1
    chr202133674921336791+CDS4.501833.43975HepG2LIN28B
    chr202133000321330061+CDS,intron-Proximal3.5069614.26353HepG2U2AF2
    chr202133721321337246+CDS,intron-Proximal4.5238610.46182HepG2U2AF2
    chr202131968721319725+CDS3.656347.66738HepG2G3BP1
    chr202130700621307041+CDS,intron-Distal,intron-Proximal3.9063814.52449HepG2BCLAF1
    chr202133007421330099+CDS3.745649.05563HepG2PPIG
    chr202132701821327078+CDS,intron-Proximal4.286018.70492HepG2SF3A3
    chr202131451121314582+CDS,intron-Proximal3.600584.79829K562EFTUD2
    chr202132137721321423+CDS3.824725.23469HepG2AQR
    chr202132472721324783+CDS,intron-Proximal3.819246.59132K562YBX3
    chr202131451821314587+CDS,intron-Proximal5.137225.07796HepG2SF3B4
    chr202131965021319762+CDS,intron-Proximal3.334458.98695K562SF3B4
    chr202133544321335510+CDS3.9651520.82585HepG2PPIG
    chr202136750621367551+CDS3.635393.24881HepG2SRSF1
    chr202133674921336790+CDS3.837923.53569K562LIN28B
    chr202132481821324869+CDS,intron-Proximal4.101239.09021HepG2PRPF8
    chr202131111421311232+CDS,intron-Proximal4.004258.88865K562EFTUD2
    chr202132136421321473+CDS3.190529.84113K562UCHL5
    chr202131120521311269+CDS,intron-Proximal4.361684.69223K562SF3B4
    chr202136762021367661+CDS,intron-Proximal4.279914.40149HepG2SRSF1
    chr202133007921330091+CDS3.182629.12012HepG2BCLAF1
    chr202131125421311289+CDS3.5640515.59767HepG2BCLAF1
    chr202131108121311137+CDS,intron-Proximal3.686767.58201HepG2SF3A3
    chr202133671721336738+CDS,intron-Proximal4.6442812.18291HepG2PPIG
    chr202131115721311176+CDS4.3381915.55920HepG2BCLAF1
    chr202130719121307239+CDS3.6618617.33040HepG2BCLAF1
    chr202134908521349130+CDS,intron-Proximal3.9174610.58235HepG2U2AF2
    chr202133542621335443+CDS,intron-Proximal3.550368.84716HepG2PPIG
    chr202132134021321380+CDS,intron-Proximal3.180394.50936K562SF3B4
    chr202131220621312249+CDS4.0524716.21501HepG2BCLAF1
    chr202133544221335476+CDS4.479024.74293HepG2ZNF800
    chr202132877621328813+CDS,intron-Proximal3.516616.75956HepG2U2AF2
    chr202134628721346369+CDS,intron-Proximal3.9076829.10781HepG2PRPF8
    chr202133670421336751+CDS,intron-Proximal4.8076816.81404HepG2U2AF2
    chr202131413821314186+CDS,intron-Proximal4.849367.50129HepG2SF3A3
    chr202132478121324821+CDS3.736225.53307K562ZNF622
    chr202131466221314740+CDS,intron-Proximal3.105315.24470HepG2EFTUD2
    chr202134724421347413+intron-Distal3.027906.16156HepG2HNRNPL
    chr202132779021327839+intron-Distal4.082494.00239HepG2KHSRP
    chr202130196021302032+intron-Distal4.054683.08314K562TARDBP
    chr202131958021319672+intron-Distal,intron-Proximal3.702914.93120K562KHSRP
    chr202129731821297437+intron-Distal3.055093.55116K562KHSRP
    chr202133704221337094+intron-Distal3.931034.10688K562KHSRP
    chr202132411521324199+intron-Distal4.038093.90026K562KHSRP
    chr202134301021343116+intron-Distal3.447585.28181HepG2MATR3
    chr202131265821312715+intron-Distal3.136704.86499HepG2U2AF2
    chr202129930621299355+intron-Distal4.182383.86368HepG2HNRNPM
    chr202135422021354286+intron-Distal4.219384.12480HepG2HNRNPM
    chr202133652221336598+intron-Distal4.818469.10637HepG2QKI
    chr202131319021313279+intron-Distal3.548043.07751K562KHSRP
    chr202135948021359547+intron-Distal4.593614.38558HepG2HNRNPM
    chr202130462421304664+intron-Distal4.230125.37814HepG2HNRNPM
    chr202130451121304575+intron-Distal3.261064.67779HepG2SUGP2
    chr202130395221304010+intron-Distal3.502178.43537HepG2HNRNPM
    chr202134336321343414+intron-Distal5.075009.34617HepG2SUGP2
    chr202132616821326243+intron-Distal4.7163712.63682HepG2KHSRP
    chr202136153121361582+intron-Distal4.434474.77477HepG2RBFOX2
    chr202133710421337183+intron-Distal,intron-Proximal3.099176.00731HepG2KHSRP
    chr202131975321319841+intron-Distal,intron-Proximal4.530805.62258K562KHSRP
    chr202128584721285891+intron-Distal3.033224.24063HepG2SUGP2
    chr202130360721303711+intron-Distal3.6765510.93835HepG2SUGP2
    chr202128420921284256+intron-Distal,intron-Proximal5.3889213.81267HepG2XPO5
    chr202132292521322999+intron-Distal3.499143.95921HepG2U2AF2
    chr202135684321356936+intron-Distal5.194436.37964HepG2ILF3
    chr202134351821343594+intron-Distal3.7897812.60743HepG2SUGP2
    chr202130395021304018+intron-Distal4.0242310.74597HepG2SUGP2
    chr202134311221343145+intron-Distal3.597275.54651HepG2SUGP2
    chr202136397021364067+intron-Distal4.292579.27432HepG2QKI
    chr202130393421303999+intron-Distal3.624067.30415HepG2MATR3
    chr202132603921326158+intron-Distal5.5633014.74977K562KHSRP
    chr202129888421298973+intron-Distal3.118924.46039HepG2MATR3
    chr202134274221342796+intron-Distal4.061753.78162K562HNRNPM
    chr202134744221347570+intron-Distal4.427824.31512K562KHSRP
    chr202130434121304391+intron-Distal3.201564.88763HepG2SUGP2
    chr202132615821326261+intron-Distal4.4665216.60718K562KHSRP
    chr202134273521342793+intron-Distal3.164739.06233HepG2SUGP2
    chr202133079321330863+intron-Distal3.941194.52298HepG2QKI
    chr202134273621342813+intron-Distal3.842838.02804HepG2HNRNPM
    chr202132604721326098+intron-Distal5.265888.61801HepG2KHSRP
    chr202132680321326863+intron-Distal3.439498.28577HepG2KHSRP
    chr202128940821289435+intron-Distal4.415523.51329HepG2MATR3
    chr202133253221332638+intron-Distal3.214373.48890K562KHSRP
    chr202134249721342536+intron-Distal3.903766.73852HepG2SUGP2
    chr202128465321284685+intron-Distal3.946833.16028HepG2SUGP2
    chr202130287421302919+intron-Distal4.198488.08894HepG2QKI
    chr202129961021299696+intron-Distal3.728934.28420HepG2HNRNPM
    chr202131950521319582+intron-Distal3.243554.39362HepG2KHSRP
    chr202129856021298632+intron-Distal4.648705.02084HepG2HNRNPM
    chr202132161121321652+intron-Distal3.332994.28919HepG2KHSRP
    chr202134198121342056+intron-Distal3.376928.45897HepG2SUGP2
    chr202129065021290758+intron-Distal4.436225.19823K562KHSRP
    chr202132632721326382+intron-Distal3.354536.15810HepG2KHSRP
    chr202129529921295366+intron-Distal3.060653.00589HepG2HNRNPC
    chr202131051021310576+intron-Distal4.794277.26804K562TARDBP
    chr202135403121354084+intron-Distal3.995653.27946HepG2HNRNPM
    chr202134272721342767+intron-Distal4.368964.66737HepG2MATR3
    chr202132578021325858+intron-Distal3.399356.57673K562KHSRP
    chr202132929521329357+intron-Distal3.044766.18642HepG2HNRNPC
    chr202130291921302977+intron-Distal4.7284811.16135HepG2QKI
    chr202134363821343696+intron-Distal3.103605.89214HepG2SUGP2
    chr202130466421304711+intron-Distal3.417213.53619HepG2HNRNPM
    chr202134983621349894+intron-Distal3.189973.80334HepG2U2AF2
    chr202129812921298203+intron-Distal4.874556.96728HepG2HNRNPM
    chr202128923221289278+intron-Distal3.379304.57452HepG2SUGP2
    chr202132647521326520+intron-Distal4.221105.18845HepG2U2AF2
    chr202132609821326162+intron-Distal4.6751411.75660HepG2KHSRP
    chr202134780121347901+intron-Distal3.2191511.02036HepG2U2AF2
    chr202134507021345126+intron-Distal4.413924.77636HepG2HNRNPL
    chr202128818721288235+intron-Distal4.180034.53347HepG2SUGP2
    chr202134520321345261+intron-Distal3.695355.82498HepG2XPO5
    chr202134362721343697+intron-Distal4.182985.61842HepG2MATR3
    chr202134239321342447+intron-Distal4.301124.31871HepG2HNRNPM
    chr202133692321336970+intron-Distal3.251013.31157HepG2KHSRP
    chr202129038621290448+intron-Distal3.572923.83822HepG2PTBP1
    chr202134965821349721+intron-Distal4.971624.80665HepG2QKI
    chr202129803321298103+intron-Distal4.524144.31512K562KHSRP
    chr202128989821289957+intron-Distal3.788135.63625HepG2HNRNPM
    chr202130410521304203+intron-Distal3.340134.53269HepG2HNRNPM
    chr202131046121310527+intron-Distal3.043493.29213HepG2KHSRP
    chr202132672921326799+intron-Distal3.749746.69500K562KHSRP
    chr202133697821337008+intron-Distal3.014265.79202HepG2U2AF2
    chr202134301021343083+intron-Distal3.343516.35394HepG2SUGP2
    chr202129963021299701+intron-Distal3.268734.35941K562KHSRP
    chr202131044021310473+intron-Distal3.821643.55754HepG2U2AF2
    chr202128562421285714+intron-Distal3.092698.48134HepG2MATR3
    chr202133651921336594+intron-Distal5.352086.23225K562QKI
    chr202134323721343358+intron-Distal4.0679815.72469HepG2HNRNPL
    chr202132726721327333+intron-Distal,intron-Proximal3.396807.32968HepG2HNRNPC
    chr202134966721349720+intron-Distal3.375484.39142HepG2PCBP2
    chr202130191721302052+intron-Distal4.217006.26655K562EIF4G2
    chr202136182121361869+intron-Distal3.878413.27946HepG2HNRNPM
    chr202128939521289439+intron-Distal3.138503.10640HepG2SUGP2
    chr202128575421285814+intron-Distal4.159987.67287HepG2MATR3
    chr202130767021307753+intron-Distal3.652383.85148K562GTF2F1
    chr202129869921298745+intron-Distal4.212133.27946HepG2HNRNPM
    chr202134386421343932+intron-Distal3.336338.28668HepG2SUGP2
    chr202130491921304950+intron-Distal3.729534.61322HepG2MATR3
    chr202134218221342253+intron-Distal3.809765.28137HepG2MATR3
    chr202130766421307742+intron-Distal3.881904.72700HepG2GTF2F1
    chr202130440821304451+intron-Distal3.031194.01262HepG2HNRNPM
    chr202136061221360677+intron-Distal3.674114.36528HepG2U2AF2
    chr202132429521324353+intron-Distal3.387513.29213HepG2KHSRP
    chr202134616121346201+intron-Proximal3.770933.82719HepG2RBM22
    chr202131118921311253+intron-Proximal5.2706412.37853HepG2EFTUD2
    chr202128417821284209+intron-Proximal4.4878313.89972HepG2XPO5
    chr202132697321327030+intron-Proximal3.552346.94545HepG2KHSRP
    chr202128411121284121+intron-Proximal3.416747.62597HepG2PRPF8
    chr202131452521314571+intron-Proximal3.3300210.85511HepG2SF3A3
    chr202133538221335418+intron-Proximal4.7419710.45858HepG2SF3A3
    chr202131483321314860+intron-Proximal4.788995.35117HepG2PRPF8
    chr202132872121328778+intron-Proximal3.642794.57435K562SF3B4
    chr202133538121335423+intron-Proximal4.951965.40008K562SF3B4
    chr202128412121284154+intron-Proximal3.501838.43093HepG2PRPF8
    chr202133828021338363+intron-Proximal4.5460510.13088HepG2QKI
    ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




    No autoregularoty interactions between protein XRN2 and its RNA.



    Diffrential Expression
    • 7,673 differentially expressed genes after Knockdown/Knockout XRN2 protein.  





    • 82 RBPs can affect the levels of XRN2.  







    7,673 differentially expressed genes after Knockdown/Knockout XRN2 protein :

    Only display 100 entries as example. Please click "View All" button to see all 7,673 entries.     

    Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
    SCYL3ENSG00000000457.9177.49650100.520100.820202.945502.19740HepG2XRN2
    FUCA2ENSG00000001036.92373.875603042.43980-0.358002.784602.05770HepG2XRN2
    GCLCENSG00000001084.6705.117101124.25960-0.673006.227905.15460HepG2XRN2
    NFYAENSG00000001167.10783.019101129.84600-0.529004.366203.46110HepG2XRN2
    ANKIB1ENSG00000001629.5539.76250935.64220-0.793605.170304.18820HepG2XRN2
    CD99ENSG00000002586.132090.872401541.406600.439803.037802.27950HepG2XRN2
    LASP1ENSG00000002834.134043.446705573.14250-0.462905.390904.38900HepG2XRN2
    TFPIENSG00000003436.102177.125205343.04760-1.2952012.3071010.80270HepG2XRN2
    RBM5ENSG00000003756.122709.575602014.934600.427204.378003.47130HepG2XRN2
    SLC7A2ENSG00000003989.12889.751503428.65200-1.9462060.8304057.89160HepG2XRN2
    ARF5ENSG00000004059.61243.16220642.351000.952508.617707.35410HepG2XRN2
    PLXND1ENSG00000004399.8872.762801518.47050-0.799003.993403.13040HepG2XRN2
    FKBP4ENSG00000004478.5904.649501670.81700-0.8851012.5303011.01200HepG2XRN2
    RBM6ENSG00000004534.103447.322602552.479000.433504.371703.46570HepG2XRN2
    RECQLENSG00000004700.11558.56410860.62720-0.623702.720402.00140HepG2XRN2
    ARHGAP33ENSG00000004777.14404.35980116.491601.795308.274807.03690HepG2XRN2
    CDC27ENSG00000004897.71720.998902548.92210-0.566604.604603.67800HepG2XRN2
    DVL2ENSG00000004975.7914.95250681.924000.424002.434301.75080HepG2XRN2
    SKAP2ENSG00000005020.8473.89780645.74440-0.446402.616501.91140HepG2XRN2
    POLR2JENSG00000005075.11787.30540473.852800.732406.462205.36940HepG2XRN2
    DHX33ENSG00000005100.8905.223501418.39640-0.647906.475005.38130HepG2XRN2
    LIG3ENSG00000005156.7500.85930745.66310-0.574104.647603.71720HepG2XRN2
    RPAP3ENSG00000005175.5338.23440484.50250-0.518502.591101.88880HepG2XRN2
    ACSM3ENSG00000005187.71220.48330514.976001.2448016.0645014.34860HepG2XRN2
    AC004381.6ENSG00000005189.15332.43540234.859700.501202.372601.69620HepG2XRN2
    SPPL2BENSG00000005206.12561.87650270.229301.056005.084904.10920HepG2XRN2
    CROTENSG00000005469.7430.29100243.736200.819905.389404.38770HepG2XRN2
    KMT2EENSG00000005483.15748.967401276.83370-0.769608.531807.27360HepG2XRN2
    RHBDD2ENSG00000005486.12574.11840403.341300.509202.046801.41570HepG2XRN2
    IBTKENSG00000005700.101149.340902081.71360-0.857004.232003.34280HepG2XRN2
    MYCBP2ENSG00000005810.13578.943801217.66810-1.0726011.4746010.01880HepG2XRN2
    FBXL3ENSG00000005812.6288.08080427.15990-0.568302.743802.02150HepG2XRN2
    PDK2ENSG00000005882.7643.38260353.422200.864205.260004.26880HepG2XRN2
    ITGA3ENSG00000005884.1326.47450160.20640-2.5973017.6124015.82880HepG2XRN2
    ZFXENSG00000005889.11953.83830630.518900.597105.755404.72230HepG2XRN2
    LAMP2ENSG00000005893.111855.423003197.95890-0.7854011.421709.96850HepG2XRN2
    ASB4ENSG00000005981.815.56300131.65910-3.0806016.9049015.14440HepG2XRN2
    GDE1ENSG00000006007.71132.321501464.34330-0.371002.698601.98300HepG2XRN2
    C19orf60ENSG00000006015.1395.9994045.729901.069801.926801.31430HepG2XRN2
    CRLF1ENSG00000006016.61513.771203524.47600-1.219302.550101.85270HepG2XRN2
    OSBPL7ENSG00000006025.7395.16550195.342401.016406.530905.43350HepG2XRN2
    YBX2ENSG00000006047.832.604004.743102.781104.108503.23320HepG2XRN2
    MAP3K14ENSG00000006062.9165.6243080.103201.047903.749802.91450HepG2XRN2
    SYNRGENSG00000006114.11461.23450738.07830-0.678305.466304.45830HepG2XRN2
    AP2B1ENSG00000006125.122575.864203366.56030-0.386203.305602.51800HepG2XRN2
    CX3CL1ENSG00000006210.62950.324001622.979300.8621010.001808.64150HepG2XRN2
    MAP3K9ENSG00000006432.11202.43640532.71240-1.3959015.8907014.18140HepG2XRN2
    BAIAP2L1ENSG00000006453.9430.84740599.74170-0.477202.687801.97350HepG2XRN2
    JHDM1DENSG00000006459.6265.136201225.51750-2.2086052.1446049.41790HepG2XRN2
    AGKENSG00000006530.11384.90190569.28470-0.564703.487102.67870HepG2XRN2
    ALDH3B1ENSG00000006534.11296.99250133.657601.151807.443806.26950HepG2XRN2
    PHTF2ENSG00000006576.12155.66910342.04910-1.135708.126906.89600HepG2XRN2
    FARP2ENSG00000006607.9755.06220949.71250-0.330901.952501.33570HepG2XRN2
    IFRD1ENSG00000006652.9476.56700638.52120-0.422102.304601.63730HepG2XRN2
    GTF2IRD1ENSG00000006704.6671.04800442.521700.600603.657002.83190HepG2XRN2
    VPS41ENSG00000006715.11531.00720706.16840-0.411302.185601.53490HepG2XRN2
    PNPLA4ENSG00000006757.7297.21430190.663400.640402.614301.90970HepG2XRN2
    ADIPOR2ENSG00000006831.91971.941602525.82690-0.357102.716301.99790HepG2XRN2
    PROM1ENSG00000007062.7221.75980602.14940-1.4411017.7640015.97810HepG2XRN2
    CCDC124ENSG00000007080.6346.52460190.117800.866004.501103.58440HepG2XRN2
    PAFAH1B1ENSG00000007168.81194.847401982.84090-0.730708.506407.25050HepG2XRN2
    KIAA0100ENSG00000007202.101842.750703437.93170-0.8997015.1838013.51440HepG2XRN2
    PAX6ENSG00000007372.162.0171035.68160-4.144807.133205.97970HepG2XRN2
    LUC7LENSG00000007392.121133.25620775.766600.546704.319703.41920HepG2XRN2
    BAIAP3ENSG00000007516.9142.5101066.901101.090903.600302.78110HepG2XRN2
    PIGQENSG00000007541.10341.96000172.943600.983402.017101.38970HepG2XRN2
    JARID2ENSG00000008083.9510.47530666.37830-0.384502.225701.56980HepG2XRN2
    CDK11AENSG00000008128.18799.20820477.713400.742306.257205.18170HepG2XRN2
    CYTH3ENSG00000008256.11129.07300190.72740-0.563301.933401.31950HepG2XRN2
    SYPL1ENSG00000008282.3853.335201284.24070-0.589705.023304.05470HepG2XRN2
    SPAG9ENSG00000008294.161418.750402695.43660-0.9259011.5732010.10940HepG2XRN2
    AASSENSG00000008311.10496.99440390.234100.348801.926901.31430HepG2XRN2
    PLEKHG6ENSG00000008323.11459.59560189.845001.2754010.328108.94560HepG2XRN2
    MPNDENSG00000008382.11259.75430151.611000.776703.193002.41660HepG2XRN2
    MGST1ENSG00000008394.81611.097101987.41660-0.302902.000701.37620HepG2XRN2
    CRY1ENSG00000008405.7184.99110369.69740-0.998907.340206.17330HepG2XRN2
    ST3GAL1ENSG00000008513.101463.80060903.662300.695806.948705.81230HepG2XRN2
    IL32ENSG00000008517.122417.208501737.525900.476204.147403.26750HepG2XRN2
    PKD1ENSG00000008710.13759.33110372.572401.027102.089601.45150HepG2XRN2
    HEATR5BENSG00000008869.7486.63080675.38290-0.472903.046002.28660HepG2XRN2
    SEC62ENSG00000008952.121346.395702028.58500-0.591403.067702.30530HepG2XRN2
    RPS20ENSG00000008988.59179.533805227.319400.8122013.7772012.17270HepG2XRN2
    CSDE1ENSG00000009307.116502.983808537.42090-0.392703.363802.56900HepG2XRN2
    UBE3CENSG00000009335.13998.736201235.46260-0.306901.943501.32800HepG2XRN2
    REV3LENSG00000009413.11973.366001354.22330-0.476403.372602.57700HepG2XRN2
    MASP2ENSG00000009724.12305.53480118.056101.371809.260807.95650HepG2XRN2
    IYDENSG00000009765.1025.665902.544103.334502.583401.88170HepG2XRN2
    MLXIPLENSG00000009950.118944.875301976.507002.1780079.4660076.27190HepG2XRN2
    BAZ1BENSG00000009954.62090.333103003.95560-0.523104.979204.01490HepG2XRN2
    NCAPD2ENSG00000010292.82784.908703575.11530-0.360403.462802.65700HepG2XRN2
    IFFO1ENSG00000010295.15571.89690298.245300.939208.813307.53580HepG2XRN2
    SEMA3GENSG00000010319.2220.15110395.53940-0.845304.934803.97480HepG2XRN2
    NISCHENSG00000010322.111493.69620985.869500.599303.007202.25160HepG2XRN2
    SLC6A13ENSG00000010379.1122.053402.544103.115702.822402.09090HepG2XRN2
    IDSENSG00000010404.13330.87470571.67590-0.788905.648704.62490HepG2XRN2
    LRRC23ENSG00000010626.10109.1323058.578500.897502.420201.73870HepG2XRN2
    FYNENSG00000010810.13475.61080888.82940-0.902108.381107.13350HepG2XRN2
    HIVEP2ENSG00000010818.4293.86690553.04040-0.912207.040705.89530HepG2XRN2
    LYPLA2ENSG00000011009.61269.62380883.559700.522901.988101.36570HepG2XRN2
    CLCN6ENSG00000011021.171801.191701228.938000.551405.029204.06040HepG2XRN2
    Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

    *: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
    **: "-log(0)" was displayed as "99999.99999".





    82 RBPs can affect the gene expression of XRN2 :

    Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
    XRN2ENSG00000088930.65528.297304319.411600.355908.805507.84600HepG2ACO1
    XRN2ENSG00000088930.69982.455405529.118500.8522012.3760011.33230HepG2AKAP1
    XRN2ENSG00000088930.64923.175404339.777200.181902.280401.57690HepG2AKAP8L
    XRN2ENSG00000088930.63423.796904336.81710-0.341002.162001.33760HepG2BCCIP
    XRN2ENSG00000088930.62869.271503768.47130-0.393303.003802.06560HepG2BCLAF1
    XRN2ENSG00000088930.64654.158107130.13540-0.615405.246703.88380HepG2CCAR1
    XRN2ENSG00000088930.63421.903104062.98340-0.247703.084602.00890HepG2YBX3
    XRN2ENSG00000088930.65040.835806156.46130-0.288406.740405.65790HepG2DAZAP1
    XRN2ENSG00000088930.63273.417503886.08560-0.247501.994101.40670HepG2DDX21
    XRN2ENSG00000088930.63602.281504708.98100-0.386503.841902.65830HepG2DDX5
    XRN2ENSG00000088930.63070.191304549.32550-0.567305.545604.69770HepG2DDX6
    XRN2ENSG00000088930.62900.375403847.88060-0.407804.114502.93410HepG2DHX30
    XRN2ENSG00000088930.63287.445504132.52870-0.330106.055705.12740HepG2DKC1
    XRN2ENSG00000088930.63006.246903989.49250-0.408207.476706.36760HepG2DNAJC21
    XRN2ENSG00000088930.62886.514203954.34060-0.4541014.0966012.74010HepG2DNAJC2
    XRN2ENSG00000088930.63034.920004374.09260-0.527304.774304.00720HepG2EIF2S1
    XRN2ENSG00000088930.61979.917204834.23270-1.2878019.3492017.67760HepG2EIF4A3
    XRN2ENSG00000088930.67027.802904706.143200.578404.827903.93400HepG2EIF4B
    XRN2ENSG00000088930.63717.140405818.49980-0.646507.940606.59260HepG2EIF4G2
    XRN2ENSG00000088930.67102.576208228.24980-0.212203.340502.68920HepG2ETF1
    XRN2ENSG00000088930.66899.562805322.936100.374203.020902.22010HepG2FIP1L1
    XRN2ENSG00000088930.63115.691804524.21120-0.538104.682603.82790HepG2G3BP1
    XRN2ENSG00000088930.62172.978002762.76520-0.346402.957602.02950HepG2GEMIN5
    XRN2ENSG00000088930.61623.562306098.77100-1.9094057.2497054.79950HepG2GPKOW
    XRN2ENSG00000088930.62837.571204027.71380-0.505307.339106.36180HepG2HNRNPA1
    XRN2ENSG00000088930.63158.755204480.11240-0.504207.041505.97680HepG2HNRNPC
    XRN2ENSG00000088930.64289.248405848.93210-0.4474010.729809.43840HepG2HNRNPF
    XRN2ENSG00000088930.63500.910705607.94830-0.6797034.4690032.41710HepG2HNRNPL
    XRN2ENSG00000088930.63560.745305820.14990-0.7089010.987109.83570HepG2HNRNPLL
    XRN2ENSG00000088930.63391.241004450.49070-0.392208.819407.78260HepG2HNRNPU
    XRN2ENSG00000088930.63834.707205759.56410-0.5868011.5996010.21600HepG2IGF2BP1
    XRN2ENSG00000088930.64102.931904546.02460-0.148002.232501.56590HepG2ILF2
    XRN2ENSG00000088930.63022.091304115.91500-0.445702.761001.44570HepG2ILF3
    XRN2ENSG00000088930.63641.182404878.18850-0.421903.852903.07990HepG2MAGOH
    XRN2ENSG00000088930.63925.785405935.32250-0.596304.522703.26310HepG2MTPAP
    XRN2ENSG00000088930.63958.660405021.35580-0.343102.551001.94100HepG2NCBP2
    XRN2ENSG00000088930.62713.346003858.55390-0.508002.693601.81870HepG2PABPC1
    XRN2ENSG00000088930.63609.828504472.48120-0.309102.212501.56140HepG2PABPC4
    XRN2ENSG00000088930.65034.920604405.192000.192702.520601.70780HepG2PARN
    XRN2ENSG00000088930.63080.591303969.47760-0.365705.931704.88340HepG2PPIL4
    XRN2ENSG00000088930.65394.748004761.496900.180002.354701.84290HepG2PTBP1
    XRN2ENSG00000088930.64152.346005827.62940-0.489007.160106.25700HepG2PUF60
    XRN2ENSG00000088930.67397.553506186.410500.257806.926306.07520HepG2PUM1
    XRN2ENSG00000088930.63803.200004399.61350-0.210203.252402.59760HepG2PUS1
    XRN2ENSG00000088930.63964.867305156.82220-0.379206.198405.31540HepG2QKI
    XRN2ENSG00000088930.65638.648904246.295800.409001.959801.35650HepG2RAVER1
    XRN2ENSG00000088930.63559.036304680.14630-0.395105.191204.29400HepG2RBM25
    XRN2ENSG00000088930.64392.474206300.19770-0.520407.377806.34200HepG2RPLP0
    XRN2ENSG00000088930.62141.785004171.33570-0.961709.873708.20430HepG2RPS10
    XRN2ENSG00000088930.62767.208904237.91600-0.614905.272704.16460HepG2RPS3A
    XRN2ENSG00000088930.62943.746403963.34380-0.4291011.6477010.46670HepG2SAFB2
    XRN2ENSG00000088930.64594.657905588.04390-0.282406.359805.36380HepG2SLBP
    XRN2ENSG00000088930.65062.600504621.903300.131301.963201.40640HepG2SMN1
    XRN2ENSG00000088930.62839.069004330.13930-0.609005.076603.75000HepG2SMNDC1
    XRN2ENSG00000088930.69094.824007767.630000.227504.566803.96950HepG2SRFBP1
    XRN2ENSG00000088930.66741.545405174.384100.3816010.051009.27470HepG2SRSF1
    XRN2ENSG00000088930.63585.739505746.25890-0.6804024.3538022.68760HepG2SRSF7
    XRN2ENSG00000088930.64691.509806744.11990-0.5236017.4728016.41690HepG2SSB
    XRN2ENSG00000088930.63724.752505672.26930-0.606809.210007.99900HepG2TARDBP
    XRN2ENSG00000088930.62552.378904324.38770-0.7607019.5714018.46210HepG2TIAL1
    XRN2ENSG00000088930.63451.333504363.14720-0.338206.646405.83950HepG2TRIM56
    XRN2ENSG00000088930.63725.845904553.66510-0.289502.304401.72600HepG2U2AF1
    XRN2ENSG00000088930.61937.069202507.58550-0.372402.874602.10220HepG2UCHL5
    XRN2ENSG00000088930.63431.504304410.33010-0.362008.241307.14210HepG2UPF1
    XRN2ENSG00000088930.62457.617503887.16980-0.661505.368603.94660HepG2UPF2
    XRN2ENSG00000088930.62799.555103795.80590-0.439202.834801.72150HepG2XPO5
    XRN2ENSG00000088930.61933.668604178.51260-1.1116022.6875020.70470HepG2XRN2
    XRN2ENSG00000088930.61904.350503219.41110-0.7575012.8766011.74450K562AQR
    XRN2ENSG00000088930.6849.777001107.33360-0.381902.880701.80170K562CCAR1
    XRN2ENSG00000088930.61818.585302308.37220-0.344103.444602.56700K562CPSF6
    XRN2ENSG00000088930.61989.434002499.97150-0.329604.565603.66980K562EIF2S2
    XRN2ENSG00000088930.6992.711301838.27910-0.8889015.6611013.59840K562EIF4A3
    XRN2ENSG00000088930.63480.762204171.48310-0.261203.426402.38460K562EIF4G2
    XRN2ENSG00000088930.61013.199302203.98350-1.1212019.2365017.03990K562GPKOW
    XRN2ENSG00000088930.62284.547703331.43910-0.544208.389207.06100K562GRSF1
    XRN2ENSG00000088930.61241.939501786.17420-0.524306.540505.66150K562HNRNPC
    XRN2ENSG00000088930.61647.880602928.80760-0.8297017.3943014.69660K562HNRNPL
    XRN2ENSG00000088930.62083.672202522.14740-0.275503.149302.19890K562HNRNPU
    XRN2ENSG00000088930.62007.431602507.70990-0.321003.092802.20290K562MAGOH
    XRN2ENSG00000088930.61771.283202151.31010-0.280402.396001.58420K562METAP2
    XRN2ENSG00000088930.61919.008302367.30820-0.302904.594203.57360K562MTPAP
    XRN2ENSG00000088930.62317.492402630.21660-0.182602.725301.98370K562NSUN2
    XRN2ENSG00000088930.63540.897504551.41370-0.362204.115603.12650K562PUF60
    XRN2ENSG00000088930.63942.675104743.36440-0.266703.578502.48740K562PUM2
    XRN2ENSG00000088930.62344.287303159.31500-0.430505.535603.27320K562RBM17
    XRN2ENSG00000088930.61930.118602336.16010-0.275402.129901.39640K562RBM22
    XRN2ENSG00000088930.61235.616501749.61010-0.5018010.370507.62150K562RPS10
    XRN2ENSG00000088930.61509.892901983.09010-0.393304.745403.61430K562SF3B4
    XRN2ENSG00000088930.62141.442002659.11980-0.312405.721504.43720K562SRPK2
    XRN2ENSG00000088930.62143.674701759.106200.285102.688701.88230K562SYNCRIP
    XRN2ENSG00000088930.61705.153502417.29300-0.503505.444604.43540K562TARDBP
    XRN2ENSG00000088930.61946.073502331.75930-0.260902.363401.61400K562TIA1
    XRN2ENSG00000088930.61152.394601540.35440-0.418603.192402.18210K562TIAL1
    XRN2ENSG00000088930.62347.288502788.88040-0.248703.606402.79450K562UPF1
    XRN2ENSG00000088930.62150.025202942.65220-0.452804.030202.57330K562UTP3
    XRN2ENSG00000088930.61781.462902386.34710-0.421705.045203.84750K562WDR3
    XRN2ENSG00000088930.6807.539601606.96710-0.992708.643106.19010K562XRN2
    Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

    *: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
    **: "-log(0)" was displayed as "99999.99999".





    1,102 alternative splicing events after Knockdown/Knockout XRN2 protein :

    Only display 100 entries as example. Please click "View All" button to see all 1,102 entries.     

    Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
    SEZBTB8OSENSG00000176261.11chr1-3310036833100393330995513309971133116033331161610.081000.000090.04375includedK562XRN2
    SESNRNP70ENSG00000104852.10chr19+4960537049606844496046464960472849607890496079920.068000.000000.00009includedK562XRN2
    SEDNAH14ENSG00000185842.10chr1+2251478542251480042251426602251428002251521802251523110.101000.000010.00790includedK562XRN2
    SEUAP1ENSG00000117143.9chr1+1625625211625625721625601121625603011625675811625676480.104000.000000.00007includedK562XRN2
    SESREK1ENSG00000153914.11chr5+6545189265454760654492906544942465455046654551620.320000.000000.00020includedK562XRN2
    SEHPS1ENSG00000107521.14chr10-1001895471001896461001889071001893991001903271001904270.395000.000000.00001includedK562XRN2
    SEWNK1ENSG00000060237.12chr12+9770319782709712489714369804309805140.158000.000230.08120includedK562XRN2
    SEGPBP1L1ENSG00000159592.6chr1-4615124746151292461262204612689746152664461528050.296000.000000.00003includedK562XRN2
    SEHBE1ENSG00000213931.1chr11-5299578529966652910285291386552679855268470.054000.000280.09468includedK562XRN2
    SECFLARENSG00000003402.15chr2+2020277182020278292020251542020256652020285572020288850.248000.000090.04237includedK562XRN2
    SEFNBP4ENSG00000109920.8chr11-4774728847747388477460234774633047752925477531130.181000.000060.03252includedK562XRN2
    SEZNF561ENSG00000171469.6chr19-9731591973172597301869730258973183797319100.246000.000010.01150includedK562XRN2
    SEGPS1ENSG00000169727.8chr17+8001025080010335800098008000984080011149800112420.088000.000030.02031includedK562XRN2
    SEMAZENSG00000103495.9chr16+2982086029821085298198902982006229821397298224850.296000.000000.00036includedK562XRN2
    SECUL2ENSG00000108094.10chr10-3537882335378929353601263536026735379106353792920.328000.000190.07216includedK562XRN2
    SEOLA1ENSG00000138430.11chr2-1751114671751115431750940351750941791751131791751132030.093000.000020.01573includedK562XRN2
    SEHNRNPCENSG00000092199.13chr14-2173177821731988217314692173149521737456217376010.065000.000000.00121includedK562XRN2
    SEHNRNPDLENSG00000152795.13chr4-8334671583346820833457818334603683347189833472820.084000.000120.05192includedK562XRN2
    SESLC40A1ENSG00000138449.6chr2-1904429441904430791904398861904400461904445381904446060.216000.000090.04443includedK562XRN2
    SEABL1ENSG00000097007.13chr9+1337551041337551391337538011337539541337554541337555440.052000.000010.00991includedK562XRN2
    SECREBZFENSG00000137504.9chr11-8537422285374337853729968537350185374567853746450.159000.000110.04934includedK562XRN2
    SEAFMIDENSG00000183077.11chr17+7620168376201819762015207620159976202026762021310.597000.000040.02338includedK562XRN2
    SEINSIG1ENSG00000186480.8chr7+1550955341550956051550944561550945561550999501551006700.134000.000000.00165includedK562XRN2
    SENUPL2ENSG00000136243.12chr7+2323679123236866232362982323638523239076232391610.258000.000000.00058includedK562XRN2
    SECD46ENSG00000117335.14chr1+2079411232079411682079403572079405402079436652079437070.122000.000030.01933includedK562XRN2
    SEDDX27ENSG00000124228.10chr20+4784755947847652478467354784688647849842478499420.097000.000150.06176includedK562XRN2
    SETHAP9-AS1ENSG00000251022.2chr4-8381914183819215838168438381692783821229838213760.222000.000180.06895includedK562XRN2
    SEANKLE2ENSG00000176915.10chr12-1333183941333184771333180041333180711333197391333198620.232000.000000.00323includedK562XRN2
    SEUQCRHENSG00000173660.7chr1+4677556846775716467747724677479946775826467759880.080000.000040.02725includedK562XRN2
    SEPCYT2ENSG00000185813.6chr17-7986507979865133798646357986477479865429798654740.229000.000110.04959includedK562XRN2
    SESLC25A17ENSG00000100372.10chr22-4119502641195087411750124117512941215198412153300.209000.000150.06080includedK562XRN2
    SERBM39ENSG00000131051.16chr20-3432722534327469343268893432693934328446343285190.244000.000160.06424includedK562XRN2
    SEZMYND8ENSG00000101040.15chr20-4584128645841370458394054583954245848908458489750.210000.000070.03831includedK562XRN2
    SEKDM5AENSG00000073614.7chr12-3952913953733946213948284019244020910.273000.000250.08709includedK562XRN2
    SERPL17ENSG00000265681.2chr18-4701810547018203470178864701795447018644470187690.144000.000150.06080includedK562XRN2
    SEC1orf63ENSG00000117616.13chr1-2557094425570989255700402557012425571640255717920.462000.000000.00007includedK562XRN2
    SESETXENSG00000107290.9chr9-1351447891351448761351368261351403721351450011351450890.306000.000000.00395includedK562XRN2
    SEEZH2ENSG00000106462.6chr7-1485160691485161511485137751485152091485166871485167790.069000.000090.04443includedK562XRN2
    SECDC42BPBENSG00000198752.5chr14-1034205341034206121034188341034189401034209381034210250.536000.000000.00300includedK562XRN2
    SERCC1ENSG00000180198.11chr1+2885703428857127288563692885645128858314288585020.054000.000150.06210includedK562XRN2
    SERFESDENSG00000175449.9chr5+9499003694990071949897649498994094991749949937860.115000.000050.03084includedK562XRN2
    SEHIST1H2ACENSG00000180573.8chr6+2612792526127989261244302612486126138281261393440.122000.000010.00928includedK562XRN2
    SESRSF11ENSG00000116754.9chr1+7069754170697658706941047069423870697950706980580.123000.000000.00182includedK562XRN2
    SERSRC2ENSG00000111011.13chr12-1230050501230051281230033851230035761230059311230059750.152000.000020.01520includedK562XRN2
    SERPS24ENSG00000138326.14chr10+7979996179799983797969517979706279800372798004550.079000.000000.00323includedK562XRN2
    SEHIRAENSG00000100084.10chr22-1939298519393054193855141938561019393308193934030.124000.000070.03855includedK562XRN2
    SEECDENSG00000122882.6chr10-749234907492370874920191749203097492762374927829-0.186000.000030.02031excludedK562XRN2
    SEMATR3ENSG00000015479.13chr5+138642927138644016138629336138629494138650363138650425-0.086000.000080.04036excludedK562XRN2
    SEPDCD10ENSG00000114209.10chr3-167443188167443261167437849167438061167452219167452305-0.280000.000170.06610excludedK562XRN2
    SEUBL7ENSG00000138629.11chr15-747530087475311974751024747512377475337774753459-0.151000.000090.04443excludedK562XRN2
    SENOL8ENSG00000198000.7chr9-950822249508241995081502950816389508394995084028-0.110000.000110.04961excludedK562XRN2
    SEERP29ENSG00000089248.6chr12+112457519112457698112451119112451413112459953112460972-0.125000.000080.04036excludedK562XRN2
    SESTX16ENSG00000124222.17chr20+572443465724454457243042572431835724556757245659-0.261000.000210.07760excludedK562XRN2
    SEMLXENSG00000108788.7chr17+407204874072057740719636407196734072085440720961-0.148000.000050.02818excludedK562XRN2
    SEAKAP8ENSG00000105127.4chr19-154798771548003515479045154791331548095615480990-0.141000.000200.07330excludedK562XRN2
    SECOMTENSG00000093010.7chr22+199492191994939719948721199488121995004919950338-0.110000.000250.08709excludedK562XRN2
    SEESYT2ENSG00000117868.11chr7-158545471158545534158542339158542414158552176158552272-0.115000.000060.03327excludedK562XRN2
    SEFRG1ENSG00000109536.7chr4+190876191190876306190873316190873442190878552190878657-0.130000.000180.06904excludedK562XRN2
    SEBRD8ENSG00000112983.13chr5-137495243137495288137492610137492956137495757137495862-0.196000.000020.01654excludedK562XRN2
    SEZNF385AENSG00000161642.13chr12-547786425477878954778211547783485478501854785065-0.075000.000250.08709excludedK562XRN2
    SER3HDM4ENSG00000198858.5chr19-902241902434901975902130913086913204-0.367000.000010.00928excludedK562XRN2
    SEPCSK9ENSG00000169174.9chr1+555121955551231955505220555057175551795055518084-0.111000.000030.02055excludedK562XRN2
    SEEDC3ENSG00000179151.7chr15-749692817496936374967301749674837498822074988328-0.118000.000150.06176excludedK562XRN2
    SEATP5BENSG00000110955.4chr12-570389545703916457038564570387395703962057039768-0.059000.000000.00000excludedK562XRN2
    SETJAP1ENSG00000137221.10chr6+434723254347240543471360434714444347249843474294-0.154000.000160.06277excludedK562XRN2
    SEFANCAENSG00000187741.10chr16-898447488984487089842149898422238984520889845258-0.122000.000000.00393excludedK562XRN2
    SEUSP21ENSG00000143258.11chr1+161130155161130296161129253161129468161130409161131030-0.352000.000130.05655excludedK562XRN2
    SEEDC4ENSG00000038358.10chr16+679096406790974067906954679072466790984767910004-0.251000.000170.06610excludedK562XRN2
    SEIFT20ENSG00000109083.9chr17-266591712665940826658427266590132666236526662504-0.419000.000040.02756excludedK562XRN2
    SEPI4KBENSG00000143393.12chr1-151298647151298849151288048151288985151299746151300133-0.335000.000080.03885excludedK562XRN2
    SEMTHFD2ENSG00000065911.7chr2+744328317443301674425742744258697443483074434953-0.092000.000010.01206excludedK562XRN2
    SEARPC1BENSG00000130429.8chr7+989749609897507898972352989724049898332498983401-0.082000.000030.02031excludedK562XRN2
    SEEIF3EENSG00000104408.5chr8-109254114109254142109252186109252304109260841109260947-0.067000.000000.00012excludedK562XRN2
    SEPUF60ENSG00000179950.9chr8-144902835144902886144900542144900704144903766144903856-0.281000.000010.00928excludedK562XRN2
    SEASH2LENSG00000129691.11chr8+379635023796365737963067379632563796389537963962-0.239000.000000.00001excludedK562XRN2
    SEATP6V0BENSG00000117410.9chr1+444413364444152044440631444407794444176144441845-0.112000.000060.03498excludedK562XRN2
    SEPRKAR1AENSG00000108946.10chr17+665111276651126066508590665086896651153466511717-0.167000.000230.08219excludedK562XRN2
    SEITGB1BP1ENSG00000119185.8chr2-956011895602299558754955886195635019563609-0.150000.000190.07044excludedK562XRN2
    SEPAQR3ENSG00000163291.10chr4-798562747985643779851323798514797986019379860548-0.345000.000000.00389excludedK562XRN2
    SERER1ENSG00000157916.14chr1+232464623247942323271232339723272222327310-0.229000.000030.02161excludedK562XRN2
    SESLC25A6ENSG00000169100.8chrX-150908415091831508133150862015107911510996-0.051000.000120.05361excludedK562XRN2
    SEEEF1DENSG00000104529.13chr8-144668388144668460144663398144663498144668898144669022-0.096000.000010.00876excludedK562XRN2
    SETMBIM1ENSG00000135926.8chr2-219150485219150661219146662219146904219157188219157309-0.056000.000060.03331excludedK562XRN2
    SEZFAS1ENSG00000177410.8chr20+4789702147897107478956404789574547905581479057970.105000.000020.01309includedHepG2XRN2
    SEANKMY1ENSG00000144504.11chr2-2414215992414216782414203532414205142414393742414395400.517000.000180.06435includedHepG2XRN2
    SEIVNS1ABPENSG00000116679.11chr1-1852756161852757571852746671852747751852761451852762710.350000.000000.00060includedHepG2XRN2
    SENUSAP1ENSG00000137804.8chr15+4165801341658061416576024165778741663724416638820.173000.000000.00015includedHepG2XRN2
    SEALDOAENSG00000149925.12chr16+3007719630077248300757443007582630078554300786870.068000.000300.08595includedHepG2XRN2
    SESREK1ENSG00000153914.11chr5+6545189265454760654492906544942465455046654551620.317000.000010.00627includedHepG2XRN2
    SEAPOC1ENSG00000130208.5chr19+4541792845417990454175034541774645418128454182060.082000.000000.00000includedHepG2XRN2
    SETRA2AENSG00000164548.6chr7-2356175023562051235613252356145923571407235715950.158000.000130.05330includedHepG2XRN2
    SESEC31AENSG00000138674.12chr4-8375208983752128837501528375021183763292837636340.437000.000000.00000includedHepG2XRN2
    SEBAG6ENSG00000204463.8chr6-3161208331612129316118583161197131612301316123790.144000.000370.09920includedHepG2XRN2
    SEWNK1ENSG00000060237.12chr12+9898869901659873779875279908579909550.313000.000360.09799includedHepG2XRN2
    SESF3B1ENSG00000115524.11chr2-1982836191982836751982832321982833121982851511982852660.067000.000040.02130includedHepG2XRN2
    SEAPOC3ENSG00000110245.7chr11+1167012911167013531167006071167006561167014881167016800.051000.000000.00001includedHepG2XRN2
    SEFLOT2ENSG00000132589.11chr17-2721287427212965272112422721133327215962272160440.076000.000280.08302includedHepG2XRN2
    SERPL10ENSG00000147403.12chrX+1536288151536289671536281431536282821536316031536318380.575000.000040.01982includedHepG2XRN2
    SEPOFUT2ENSG00000186866.12chr21-4668593646686142466838424668555046687504466876280.171000.000080.03882includedHepG2XRN2
    SEKHKENSG00000138030.8chr2+2731766727317802273151992731531627319596273196690.381000.000270.08224includedHepG2XRN2





    12 RBPs can affect the splicing of XRN2 :

    Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
    SEXRN2ENSG00000088930.6chr20+213147152131482321314574213146322131968121319726-0.131000.000000.00000excludedK562SRSF1
    SEXRN2ENSG00000088930.6chr20+2134727421347428213462102134634221349100213492280.065000.000000.00006includedK562PRPF8
    SEXRN2ENSG00000088930.6chr20+213143222131447521314181213142562131457421314632-0.069000.000440.01029excludedHepG2U2AF1
    SEXRN2ENSG00000088930.6chr20+213491002134922821346210213463422136263121362695-0.101000.000000.00000excludedK562AQR
    SEXRN2ENSG00000088930.6chr20+213143412131447521314181213142562131457421314632-0.069000.000000.00001excludedK562AQR
    SEXRN2ENSG00000088930.6chr20+213372232133730321336615213368152133837321338430-0.078000.000070.00121excludedK562AQR
    SEXRN2ENSG00000088930.6chr20+213111182131117721309196213093082131125321311343-0.074000.000160.00257excludedK562AQR
    SEXRN2ENSG00000088930.6chr20+213675052136764421362631213626952136991021370463-0.057000.000050.00093excludedK562AQR
    SEXRN2ENSG00000088930.6chr20+213121982131227121311225213113432131240521312456-0.081000.000000.00010excludedK562AQR
    SEXRN2ENSG00000088930.6chr20+213069162130704421283941212841112130712721307239-0.163000.000010.00051excludedK562U2AF1
    SEXRN2ENSG00000088930.6chr20+2134727421347428213462102134634221349100213492280.064000.000000.00000includedHepG2HNRNPL
    SEXRN2ENSG00000088930.6chr20+2134727421347428213462102134634221349100213492280.140000.000000.00000includedK562HNRNPL
    SEXRN2ENSG00000088930.6chr20+213147152131482321314574213146322131968121319726-0.139000.000000.00000excludedHepG2SRSF1
    SEXRN2ENSG00000088930.6chr20+213147532131482321314574213146322131968121319726-0.067000.000120.00549excludedHepG2SF3A3
    SEXRN2ENSG00000088930.6chr20+213069162130704421283941212841112130712721307239-0.224000.000000.00000excludedK562U2AF2
    SEXRN2ENSG00000088930.6chr20+213111182131117721283941212841112131125321311343-0.111000.004660.08648excludedK562RBM15
    SEXRN2ENSG00000088930.6chr20+213069162130704421283941212841112130712721307239-0.056000.000030.00191excludedHepG2HNRNPC
    SEXRN2ENSG00000088930.6chr20+213069162130704421283941212841112130712721307239-0.084000.007320.09268excludedK562HNRNPC
    A3SSXRN2ENSG00000088930.6chr20+2133669221336815213367172133681521335267213355100.164000.000000.00000longerK562AQR
    A3SSXRN2ENSG00000088930.6chr20+2131965721319726213196812131972621314715213148230.100000.000000.00000longerK562AQR
    A5SSXRN2ENSG00000088930.6chr20+2132897821329179213289782132906821330026213300990.058000.000110.00280longerK562AQR
    A5SSXRN2ENSG00000088930.6chr20+213287462132889121328746213288802132897821329179-0.069000.000080.00204shorterK562AQR
    A5SSXRN2ENSG00000088930.6chr20+2136750521367644213675052136760321369910213704630.206000.000260.06665longerK562FXR2
    MXEXRN2ENSG00000088930.6chr20+21337160213373032133837321338430213367172133681521346058213461270.062000.000360.009301includedHepG2U2AF1
    MXEXRN2ENSG00000088930.6chr20+21307127213072392131111821311177212839822128411121311253213113430.116000.003700.027961includedK562AQR
    MXEXRN2ENSG00000088930.6chr20+21309143213093082131111821311177213071272130723921311253213113430.112000.000270.002931includedK562AQR
    MXEXRN2ENSG00000088930.6chr20+21309100213093082131111821311177213071272130723921311253213113430.119000.000130.001541includedK562AQR
    MXEXRN2ENSG00000088930.6chr20+21314574213146322131471521314823213141812131425621319681213197260.084000.000000.000001includedK562AQR
    MXEXRN2ENSG00000088930.6chr20+21307127213072392131111821311177212839822128411121311253213113430.179000.000020.000631includedK562U2AF2
    MXEXRN2ENSG00000088930.6chr20+21309220213093082131111821311177213071272130723921311253213113430.098000.000100.006361includedHepG2SF3A3
    MXEXRN2ENSG00000088930.6chr20+21309223213093082131111821311177213071272130723921311253213113430.056000.002840.074311includedHepG2SF3A3
    MXEXRN2ENSG00000088930.6chr20+21307127213072392131111821311177212839822128411121311253213113430.106000.002690.057471includedK562TARDBP
    MXEXRN2ENSG00000088930.6chr20+2131111821311177213112532131134321309196213093082131219821312271-0.103000.006720.059212includedHepG2SFPQ
    MXEXRN2ENSG00000088930.6chr20+21307127213072392131111821311177212839822128411121311253213113430.076000.000200.002111includedHepG2U2AF2

    *: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
    **: "-log(0)" was displayed as "99999.99999".





    No autoregularoty alternative splicing events between protein XRN2 and its RNA.