GTF2IRD1

General Information

Gene Name       : GTF2IRD1
Gene ID             : ENSG00000006704.10
Essential Gene : No

Functions

Localization

Domains (AlphaFold: GTF2IRD1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878GTF2IRD1ENSG00000006704.101.231.901.56ENCSR000AEF
HepG2GTF2IRD1ENSG00000006704.1023.5021.4522.48ENCSR985KAT
K562GTF2IRD1ENSG00000006704.1017.2116.4516.83ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for GTF2IRD1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • GTF2IRD1 RNA is bound by 37 proteins.  







eCLIP assay for GTF2IRD1 is not avaliable on ENCORE database.





37 proteins are bound to GTF2IRD1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr77401676774016874+3'-UTR3.230953.48890K562KHSRP
chr77401682174016874+3'-UTR5.8092613.91986K562PUM2
chr77401674474016821+3'-UTR,CDS5.0338619.79724K562PUM2
chr77386843373868500+5'-UTR4.801437.46114HepG2DDX3X
chr77386836273868472+5'-UTR3.688058.51568HepG2PCBP2
chr77393843073938485+CDS,intron-Proximal3.360156.47139HepG2PPIG
chr77392991273930023+CDS,intron-Proximal4.5794410.40891K562PRPF8
chr77400418774004256+CDS4.026978.12130HepG2PPIG
chr77392728573927351+CDS,intron-Proximal3.760998.16617HepG2PRPF8
chr77395247173952502+CDS3.176534.24993HepG2PPIG
chr77393250673932568+CDS3.136686.00788HepG2PPIG
chr77400418474004258+CDS,intron-Proximal5.190927.69747K562ZNF622
chr77400515274005179+CDS,intron-Proximal3.627124.41267HepG2PPIG
chr77396147973961511+CDS,intron-Distal3.437704.13746HepG2PPIG
chr77393265173932717+CDS,intron-Proximal4.390013.93614HepG2AQR
chr77393244973932516+CDS,intron-Proximal3.359093.32861HepG2U2AF2
chr77395300973953039+CDS,intron-Proximal3.824265.24452HepG2PPIG
chr77392248873922533+CDS3.562794.25541HepG2GRWD1
chr77400937074009416+CDS,intron-Proximal3.799314.16174HepG2PRPF8
chr77396008773960138+CDS3.834234.66686K562DDX24
chr77395060373950653+CDS,intron-Proximal5.284595.69951K562AQR
chr77393543673935539+CDS,intron-Distal,intron-Proximal3.455944.84442HepG2SF3B4
chr77392715973927249+CDS,intron-Proximal4.4983512.76865HepG2PPIG
chr77392974473929805+CDS,intron-Proximal3.775875.55508K562BUD13
chr77394409273944212+CDS3.352476.18332HepG2GRWD1
chr77392989073930054+CDS,intron-Distal,intron-Proximal4.2778516.82728HepG2PRPF8
chr77394406073944097+CDS,intron-Proximal3.484066.20926HepG2PPIG
chr77396954673969597+CDS,intron-Proximal3.598745.73990HepG2PRPF8
chr77392243773922488+CDS3.975663.82000HepG2GRWD1
chr77392248373922534+CDS,intron-Proximal3.334647.36645HepG2PPIG
chr77392976773929810+CDS,intron-Proximal4.166128.12130HepG2PPIG
chr77395057673950649+CDS,intron-Proximal3.735656.02950HepG2PRPF8
chr77392724973927303+CDS,intron-Proximal4.0492112.11762HepG2PPIG
chr77397331973973351+CDS3.732413.86355HepG2PPIG
chr77393246373932502+CDS,intron-Proximal3.412705.86107HepG2PPIG
chr77386914273869228+intron-Distal3.728143.24367K562DDX52
chr77391406473914105+intron-Distal3.498473.56210K562EIF4G2
chr77391041873910577+intron-Distal4.169097.08696K562TARDBP
chr77389923373899363+intron-Distal4.520134.57471HepG2SFPQ
chr77386911473869221+intron-Distal3.491413.85148K562GTF2F1
chr77389708273897247+intron-Distal4.271234.84226K562NONO
chr77386913173869237+intron-Distal3.4231613.87782HepG2NKRF
chr77391098073911051+intron-Distal4.636045.20271K562FAM120A
chr77387548373875564+intron-Distal3.980684.11089HepG2XRN2
chr77386966173869714+intron-Distal3.963756.61028HepG2CSTF2T
chr77388303773883093+intron-Distal4.313614.62276K562TARDBP
chr77386938973869452+intron-Distal4.047416.96499HepG2XPO5
chr77386914573869247+intron-Distal3.012413.80339HepG2PRPF4
chr77389462073894749+intron-Distal4.646895.14276HepG2NKRF
chr77391089473910968+intron-Distal5.505206.69377HepG2DKC1
chr77391084573911021+intron-Distal6.0976216.29438K562EIF4G2
chr77395432273954405+intron-Distal,intron-Proximal3.978454.34418HepG2RBM22
chr77386915473869227+intron-Distal3.324714.07903K562EWSR1
chr77386867873868755+intron-Distal3.1684711.63878HepG2NKRF
chr77386866673868757+intron-Distal3.466573.64169K562XRN2
chr77388098373881194+intron-Distal3.347534.16645HepG2HNRNPK
chr77386990573869953+intron-Distal3.901393.37414K562CSTF2T
chr77390951173909602+intron-Distal5.1142113.82407K562EIF4G2
chr77391017173910281+intron-Distal3.139003.38007HepG2STAU2
chr77386959773869615+intron-Distal4.305574.86859HepG2CSTF2T
chr77391098873911097+intron-Distal3.600614.91684K562CSTF2T
chr77391060473910696+intron-Distal3.810873.06406HepG2IGF2BP1
chr77391089773911003+intron-Distal3.751084.49647HepG2RBFOX2
chr77386915673869228+intron-Distal4.704466.16396K562NONO
chr77389350573893594+intron-Distal3.409846.54075HepG2HNRNPK
chr77386877773868834+intron-Distal4.338979.56617HepG2CSTF2T
chr77386876873868833+intron-Distal3.069814.41221HepG2FAM120A
chr77386879473868838+intron-Distal3.877933.30664K562NONO
chr77391062973910699+intron-Distal4.311743.40087HepG2RBFOX2
chr77387728473877433+intron-Distal3.392226.10098K562NONO
chr77386869073868748+intron-Distal3.762496.76820HepG2XRN2
chr77386863973868759+intron-Distal3.0632214.73731HepG2CSTF2T
chr77388796573888061+intron-Distal4.072794.09469HepG2XPO5
chr77386867573868751+intron-Distal3.542049.62988HepG2FAM120A
chr77394330973943420+intron-Distal5.659435.62492K562EIF4G2
chr77389023873890347+intron-Distal4.524325.86222K562NONO
chr77391090173911007+intron-Distal4.372194.56734HepG2FAM120A
chr77391096973911063+intron-Distal4.117453.91772K562TARDBP
chr77386963873869730+intron-Distal3.271935.20317K562NONO
chr77391374673913805+intron-Distal4.840964.67055K562EIF4G2
chr77386923573869293+intron-Distal4.038893.30664K562NONO
chr77394323573943282+intron-Distal4.760734.67055K562EIF4G2
chr77386870873868754+intron-Distal3.941753.82910K562NONO
chr77386963473869732+intron-Distal3.137937.95308HepG2NKRF
chr77386889773868979+intron-Distal3.147794.96449HepG2NKRF
chr77386868973868739+intron-Distal4.726675.12413K562GEMIN5
chr77393013573930217+intron-Distal4.042624.07750HepG2HNRNPK
chr77398047973980565+intron-Distal4.340703.98095HepG2HNRNPL
chr77397584373975937+intron-Distal4.786537.00579HepG2PRPF4
chr77387548073875565+intron-Distal3.402894.36184HepG2PRPF4
chr77391432373914417+intron-Distal4.359704.89657K562EIF4G2
chr77386916673869222+intron-Distal3.006703.01032HepG2LARP4
chr77389180673891882+intron-Distal3.142483.18011HepG2FAM120A
chr77397465973974742+intron-Distal4.802966.36553HepG2RBFOX2
chr77387560673875739+intron-Distal3.438444.48585K562NONO
chr77391422173914373+intron-Distal3.990433.69425K562TARDBP
chr77386964673869720+intron-Distal3.245363.99385K562CSTF2T
chr77387173273871808+intron-Distal4.436974.92524K562TARDBP
chr77386906173869116+intron-Distal3.468993.93915K562EWSR1
chr77389925473899312+intron-Distal3.723703.07008K562NONO
chr77391072673910804+intron-Distal3.882713.08314K562TARDBP
chr77395177873951966+intron-Distal3.778369.70093HepG2HNRNPL
chr77391102173911102+intron-Distal6.4759212.95876K562EIF4G2
chr77390953773909586+intron-Distal3.649213.52528HepG2FAM120A
chr77387185573872004+intron-Distal6.0469568.72143HepG2PCBP2
chr77386925673869293+intron-Distal3.824966.23207HepG2NKRF
chr77386913373869243+intron-Distal4.291748.45389K562CSTF2T
chr77389349973893591+intron-Distal3.791984.70992HepG2DDX59
chr77387546073875569+intron-Distal3.644045.13321HepG2RBFOX2
chr77395178873951901+intron-Distal3.602415.12089K562HNRNPL
chr77391035473910418+intron-Distal4.365154.85626K562TARDBP
chr77386904473869133+intron-Distal3.335773.50009K562CSTF2T
chr77391019973910260+intron-Distal4.443924.02776HepG2FAM120A
chr77391016273910270+intron-Distal4.9740116.27966K562EIF4G2
chr77386887073868986+intron-Distal3.1789210.38771HepG2CSTF2T
chr77386940073869420+intron-Distal3.247833.69530HepG2CSTF2T
chr77386914073869215+intron-Distal3.979009.35150HepG2FAM120A
chr77393239073932469+intron-Proximal5.2549812.02813K562SF3B4
chr77394946873949542+intron-Proximal5.060865.69951K562AQR
chr77392996273930009+intron-Proximal3.788305.19069HepG2TIAL1
chr77392993573929962+intron-Proximal3.623224.49490HepG2TIAL1
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for GTF2IRD1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for GTF2IRD1 is not available on ENCORE database.

  • 39 RBPs can affect the levels of GTF2IRD1.  








The Knockdown/knockout RNA-Seq assay for GTF2IRD1 is not available on ENCORE database.





39 RBPs can affect the gene expression of GTF2IRD1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
GTF2IRD1ENSG00000006704.6621.15800853.13720-0.457802.672702.14980HepG2AKAP1
GTF2IRD1ENSG00000006704.6426.33460807.15550-0.920902.407801.69740HepG2CNOT7
GTF2IRD1ENSG00000006704.6853.86000727.433000.231102.002101.35560HepG2DAZAP1
GTF2IRD1ENSG00000006704.61176.21710702.070200.744406.907805.96630HepG2DDX6
GTF2IRD1ENSG00000006704.6474.46250369.721500.359802.744902.09610HepG2DNAJC2
GTF2IRD1ENSG00000006704.6401.49860745.75500-0.893308.307307.20310HepG2EIF4A3
GTF2IRD1ENSG00000006704.6481.11560698.03420-0.536903.650402.89050HepG2G3BP1
GTF2IRD1ENSG00000006704.6583.62170376.548700.632105.082804.24280HepG2HNRNPA1
GTF2IRD1ENSG00000006704.6888.64240706.944800.329902.009001.40700HepG2HNRNPK
GTF2IRD1ENSG00000006704.6611.05010416.083900.554306.120005.24840HepG2HNRNPU
GTF2IRD1ENSG00000006704.6657.74340414.848400.664802.594801.53920HepG2NONO
GTF2IRD1ENSG00000006704.6498.51920371.111300.425703.203202.41570HepG2PPIL4
GTF2IRD1ENSG00000006704.6492.22440661.47320-0.426404.249703.51510HepG2PUS1
GTF2IRD1ENSG00000006704.61104.15860830.234400.411304.190003.16110HepG2RBM15
GTF2IRD1ENSG00000006704.6546.63150370.533300.560905.883804.99940HepG2SAFB2
GTF2IRD1ENSG00000006704.6574.15120432.091300.410003.772103.04100HepG2SMN1
GTF2IRD1ENSG00000006704.61553.28600931.584900.7375017.7091016.73130HepG2SRFBP1
GTF2IRD1ENSG00000006704.6580.04440772.09590-0.412601.712901.31580HepG2SRSF1
GTF2IRD1ENSG00000006704.6764.37920552.277700.468802.497401.55040HepG2SRSF3
GTF2IRD1ENSG00000006704.61023.81750808.828400.340003.744103.16780HepG2SSB
GTF2IRD1ENSG00000006704.6696.01690407.920700.7707011.8435010.79440HepG2TRIM56
GTF2IRD1ENSG00000006704.6917.80460712.125100.366002.088401.36760HepG2UBE2L3
GTF2IRD1ENSG00000006704.6384.88930265.525500.535502.726001.97160HepG2UCHL5
GTF2IRD1ENSG00000006704.6671.04800442.521700.600603.657002.83190HepG2XRN2
GTF2IRD1ENSG00000006704.61260.92110899.720700.486807.258706.40290K562AGGF1
GTF2IRD1ENSG00000006704.6700.88640929.44050-0.407203.046001.74120K562APOBEC3C
GTF2IRD1ENSG00000006704.6664.46620850.60470-0.356302.016901.50060K562AQR
GTF2IRD1ENSG00000006704.6483.85130367.939400.395002.455901.46790K562CSTF2
GTF2IRD1ENSG00000006704.6814.05750554.288700.554405.552204.00600K562DDX3X
GTF2IRD1ENSG00000006704.61063.11650842.352900.335703.560902.83410K562DDX47
GTF2IRD1ENSG00000006704.6108.32770300.88160-1.4738011.418909.78360K562G3BP2
GTF2IRD1ENSG00000006704.6916.12650697.102700.394103.330702.15120K562HNRNPA1
GTF2IRD1ENSG00000006704.61018.24960771.970300.399404.050202.96080K562HNRNPU
GTF2IRD1ENSG00000006704.6759.52880598.255700.344202.112501.41440K562HSPD1
GTF2IRD1ENSG00000006704.6827.699301149.26560-0.473503.585902.66000K562PUF60
GTF2IRD1ENSG00000006704.6154.42750287.09170-0.894603.711202.02740K562RAVER1
GTF2IRD1ENSG00000006704.6596.50730420.364800.504802.652201.85530K562RPS19
GTF2IRD1ENSG00000006704.6677.38020427.026300.665502.922102.07850K562TIA1
GTF2IRD1ENSG00000006704.6588.42140419.289100.488802.407101.40320K562TRA2A
GTF2IRD1ENSG00000006704.6165.73990291.72530-0.815704.646303.15440K562U2AF1
GTF2IRD1ENSG00000006704.6115.73540301.26480-1.3802013.9322012.11060K562U2AF2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for GTF2IRD1 is not available on ENCORE database.





5 RBPs can affect the splicing of GTF2IRD1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEGTF2IRD1ENSG00000006704.6chr7+7395210773952308739504967395060573952465739525030.595000.000000.00000includedHepG2HNRNPK
SEGTF2IRD1ENSG00000006704.6chr7+739590847395913273954208739542987396007373960139-0.153000.003580.03530excludedK562AQR
SEGTF2IRD1ENSG00000006704.6chr7+739697227396982473969503739695537397196873972052-0.220000.002110.08415excludedHepG2PCBP1
SEGTF2IRD1ENSG00000006704.6chr7+7395211673952308739504967395060573952465739525030.366000.000000.00029includedK562HNRNPK
A3SSGTF2IRD1ENSG00000006704.6chr7+7396972273969824739697677396982473969503739695530.377000.001030.08935longerHepG2SRSF1
A3SSGTF2IRD1ENSG00000006704.6chr7+739697227396982473969767739698247396950373969553-0.167000.002600.05652shorterHepG2U2AF2
A3SSGTF2IRD1ENSG00000006704.6chr7+7396948473969553739695037396955373961432739616160.067000.002780.01723longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for GTF2IRD1 is not avaliable on ENCORE database.