RPS19

General Information

Gene Name : RPS19
Gene ID : ENSG00000105372.7
Essential Gene : Yes

Functions

rRNA processing
Ribosome & basic translation

Localization

Not Available

Domains (AlphaFold: RPS19)

No checked domain (RRM, ZNF, KH, Helicase, Nuclease, dRBM or PUM_HD)

Antibody Validation

Bethyl Labs: A304-002A

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	RPS19	ENSG00000105372.7	481.43	1806.19	1143.81	ENCSR000AEF
HepG2	RPS19	ENSG00000105372.7	2464.93	1573.01	2018.97	ENCSR985KAT
K562	RPS19	ENSG00000105372.7	1502.59	1383.32	1442.95	ENCSR000AEO

Assays

2 Released experiments are available on ENCORE database.

Assay Type	Exp_Name	ENCODE ID	Target label	Biosample	Status	Linked Antibody	Controls	Method	Note
knockdown followed by RNA-seq	RPS19-BGKLV19-K562	ENCSR098NHI	RPS19	K562	Released		ENCSR661HEL	shRNA	KD% = no AB,no AB
knockdown followed by RNA-seq	RPS19-BGHLV16-HepG2	ENCSR486AIO	RPS19	HepG2	Released		ENCSR689PHN	shRNA	KD% = no AB,no AB

eCLIP

No eCLIP experiment available

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
RPS19	ENCAB493LQE	A304-002A	1			Released, ENCODE4		BGKcLV46-73, Submitted, ENCORE2

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project
RPS19	K562	shRNA	ENCSR098NHI	ENCSR661HEL	RPS19_BGKLV19_45B,RPS19_BGKLV19_46B	NT_BGKLV19_1B,NT_BGKLV19_2B	no AB,no AB	Released	ENCODE3
RPS19	HepG2	shRNA	ENCSR486AIO	ENCSR689PHN	RPS19_BGHLV16_45,RPS19_BGHLV16_46	NT_BGHLV16_1,NT_BGHLV16_2	no AB,no AB	Released	ENCODE3
RPS19	K562	CRISPR			BGKcLV30-69,BGKcLV30-70	BGKcLV30-1,BGKcLV30-2	0.0,0.0	NotSatisfied	ENCODE4
RPS19	K562	CRISPR			BGKcLV35-55,BGKcLV35-56	BGKcLV35-1,BGKcLV35-2	0.0,0.0	NotSatisfied	ENCORE2
RPS19	K562	CRISPR			BGKcLV35-57,BGKcLV35-58	BGKcLV35-1,BGKcLV35-2	0.0,0.0	NotSatisfied	ENCORE2
RPS19	K562	CRISPR			RPS19-BGKcLV46-73,RPS19-BGKcLV46-74	NT-BGKcLV46-1,NT-BGKcLV46-2	48.8,50.6	Submitting	ENCORE2
RPS19	K562	CRISPR			BGKcLV46-75,BGKcLV46-76	BGKcLV46-1,BGKcLV46-2	0.0,0.0	NotSatisfied	ENCORE2
RPS19	HepG2	CRISPR			BGHcLV32-67,BGHcLV32-68	BGHcLV32-1,BGHcLV32-2	0.0,0.0	NotSatisfied	ENCODE4
RPS19	HepG2	CRISPR			BGHcLV47-59,BGHcLV47-60	BGHcLV47-1,BGHcLV47-2	0.0,29.0	NotSatisfied	ENCORE2

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
RPS19	Product_ID: A304-002A Lot_ID: 1 Source: Bethyl Labs Target Name: RPS19-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for RPS19 is not avaliable on ENCORE database.

Proteins bound to RNA

RPS19 RNA is bound by 33 proteins.

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eCLIP assay for RPS19 is not avaliable on ENCORE database.

33 proteins are bound to RPS19 RNA:

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Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr19	42373141	42373150	+	3'-UTR,CDS	4.02499	400.00000	K562	YBX3
chr19	42373210	42373233	+	3'-UTR,CDS	4.28511	400.00000	K562	YBX3
chr19	42373150	42373152	+	3'-UTR,CDS	3.66900	400.00000	K562	YBX3
chr19	42373152	42373168	+	3'-UTR,CDS	4.18341	400.00000	K562	YBX3
chr19	42373246	42373254	+	3'-UTR,CDS	5.88289	400.00000	HepG2	LIN28B
chr19	42373134	42373141	+	3'-UTR,CDS	4.04398	400.00000	K562	YBX3
chr19	42373204	42373232	+	3'-UTR,CDS	4.96173	400.00000	K562	LIN28B
chr19	42373175	42373183	+	3'-UTR,CDS	4.37388	400.00000	K562	YBX3
chr19	42373183	42373188	+	3'-UTR,CDS	4.26057	400.00000	K562	YBX3
chr19	42373109	42373113	+	3'-UTR,CDS	3.81505	400.00000	K562	YBX3
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 179 entries

eCLIP assay for RPS19 is not avaliable on ENCORE database.

Diffrential Expression

12,063 differentially expressed genes after Knockdown/Knockout RPS19 protein.

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133 RBPs can affect the levels of RPS19.

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12,063 differentially expressed genes after Knockdown/Knockout RPS19 protein :

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Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
TFPI	ENSG00000003436.10	2618.92720	7045.87430	-1.42780	57.39620	55.27640	HepG2	RPS19
ITGA3	ENSG00000005884.13	596.74450	53.44070	3.48100	40.32810	38.47870	HepG2	RPS19
ST3GAL1	ENSG00000008513.10	435.16310	1097.85640	-1.33510	28.74790	27.11740	HepG2	RPS19
DBNDD1	ENSG00000003249.9	1390.59400	612.63720	1.18250	24.92700	23.38450	HepG2	RPS19
SLC7A2	ENSG00000003989.12	1096.99790	4352.04860	-1.98810	24.88620	23.34500	HepG2	RPS19
ZNF195	ENSG00000005801.12	788.12320	302.22740	1.38270	24.15550	22.62910	HepG2	RPS19
TNFRSF12A	ENSG00000006327.9	730.25980	277.26120	1.39710	23.08610	21.57810	HepG2	RPS19
RHBDD2	ENSG00000005486.12	833.87820	335.55340	1.31320	22.79620	21.30010	HepG2	RPS19
AASS	ENSG00000008311.10	144.43770	441.90260	-1.61330	22.05960	20.58640	HepG2	RPS19
SPATA20	ENSG00000006282.15	1765.09210	860.19070	1.03690	21.95450	20.48510	HepG2	RPS19
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 100 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

133 RBPs can affect the gene expression of RPS19 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
RPS19	ENSG00000105372.2	7751.41720	20183.79360	-1.38070	143.47060	141.40830	HepG2	SRSF1
RPS19	ENSG00000105372.2	6520.64410	18573.12670	-1.51010	135.27400	132.96070	HepG2	PTBP1
RPS19	ENSG00000105372.2	684.83500	4221.66730	-2.62400	101.59800	98.87620	HepG2	RPS19
RPS19	ENSG00000105372.2	7139.93740	16420.51990	-1.20150	100.80230	98.50450	HepG2	SRSF9
RPS19	ENSG00000105372.2	9504.14300	20670.20070	-1.12090	82.86010	80.95290	HepG2	NELFE
RPS19	ENSG00000105372.2	8041.87500	20115.39570	-1.32270	75.58390	73.15410	HepG2	QKI
RPS19	ENSG00000105372.2	658.10010	8049.77350	-3.61260	75.97390	72.37860	K562	RPS19
RPS19	ENSG00000105372.2	16721.95420	9777.06740	0.77420	41.84700	39.68200	K562	AGGF1
RPS19	ENSG00000105372.2	8379.66620	18255.92350	-1.12340	40.89540	38.59330	HepG2	RBM25
RPS19	ENSG00000105372.2	10957.33990	18253.12740	-0.73620	36.57570	34.80210	HepG2	PCBP1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 157 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for RPS19 is not available on ENCORE database.

5 RBPs can affect the splicing of RPS19 :

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Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	RPS19	ENSG00000105372.2	chr19	+	42373068	42373284			42365180	42365281	42375418	42376994	0.67400	0.00000	0.00000	included	K562	AQR
MXE	RPS19	ENSG00000105372.2	chr19	+	42373040	42373284	42373768	42373823	42365180	42365281	42375418	42375484	0.05600	0.00000	0.00000	1included	K562	AQR
MXE	RPS19	ENSG00000105372.2	chr19	+	42373068	42373284	42373768	42373823	42365180	42365281	42375418	42376994	0.22100	0.00000	0.00000	1included	K562	AQR
MXE	RPS19	ENSG00000105372.2	chr19	+	42373056	42373284	42373768	42373823	42365180	42365281	42375418	42375484	0.21300	0.00000	0.00000	1included	K562	AQR
MXE	RPS19	ENSG00000105372.2	chr19	+	42373109	42373284	42373768	42373823	42365180	42365281	42375418	42376994	0.09100	0.00000	0.00000	1included	HepG2	SF3B4
MXE	RPS19	ENSG00000105372.2	chr19	+	42373100	42373284	42373768	42373823	42365180	42365281	42375418	42375484	0.05700	0.00000	0.00009	1included	K562	TRA2A
MXE	RPS19	ENSG00000105372.2	chr19	+	42373109	42373284	42373768	42373823	42365180	42365281	42375418	42376994	0.07100	0.00000	0.00008	1included	K562	SF3B4
MXE	RPS19	ENSG00000105372.2	chr19	+	42373100	42373284	42373768	42373823	42365180	42365281	42375418	42375484	-0.08300	0.00039	0.00738	2included	K562	U2AF2
SE	RPS19	ENSG00000105372.2	chr19	+	42373109	42373284			42365180	42365281	42375418	42376994	0.63100	0.00104	0.04775	included	HepG2	SF3B4
MXE	RPS19	ENSG00000105372.2	chr19	+	42373100	42373284	42373768	42373823	42365180	42365281	42375418	42375484	-0.07500	0.00836	0.09038	2included	K562	U2AF1

Showing 1 to 10 of 10 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

RPS19

General Information

Functions

Localization

Domains (AlphaFold: RPS19)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for RPS19 is not avaliable on ENCORE database.

33 proteins are bound to RPS19 RNA:

eCLIP assay for RPS19 is not avaliable on ENCORE database.

Diffrential Expression

12,063 differentially expressed genes after Knockdown/Knockout RPS19 protein :

133 RBPs can affect the gene expression of RPS19 :

The Knockdown/knockout RNA-Seq assay for RPS19 is not available on ENCORE database.

5 RBPs can affect the splicing of RPS19 :

The Knockdown/knockout RNA-Seq assay for RPS19 is not avaliable on ENCORE database.