M6PR

General Information

Gene Name : M6PR
Gene ID : ENSG00000003056.7
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: M6PR)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	M6PR	ENSG00000003056.7	100.76	99.08	99.92	ENCSR000AEF
HepG2	M6PR	ENSG00000003056.7	81.25	79.26	80.25	ENCSR985KAT
K562	M6PR	ENSG00000003056.7	85.66	86.94	86.30	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for M6PR is not avaliable on ENCORE database.

Proteins bound to RNA

M6PR RNA is bound by 17 proteins.

eCLIP assay for M6PR is not avaliable on ENCORE database.

17 proteins are bound to M6PR RNA:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr12	9098853	9098900	-	3'-UTR,CDS,intron-Distal,intron-Proximal	4.14515	5.76817	K562	DDX3X
chr12	9096397	9096499	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.89186	3.34184	HepG2	GRWD1
chr12	9095999	9096068	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.98220	3.79230	K562	SND1
chr12	9095044	9095117	-	3'-UTR,CDS,intron-Distal,intron-Proximal	5.10021	7.03502	HepG2	SND1
chr12	9096119	9096184	-	3'-UTR,CDS,intron-Distal,intron-Proximal	4.10331	5.97994	K562	AQR
chr12	9098935	9099039	-	3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal	3.83975	5.55825	HepG2	U2AF2
chr12	9098018	9098076	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.27411	4.64860	HepG2	SND1
chr12	9096417	9096499	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.94677	5.20093	K562	DDX24
chr12	9094975	9095132	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.73142	6.51082	HepG2	PPIG
chr12	9098079	9098178	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.78208	7.31650	HepG2	SND1
chr12	9098131	9098197	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.49235	3.99908	K562	BUD13
chr12	9095010	9095044	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.41095	3.57831	HepG2	SND1
chr12	9098012	9098071	-	3'-UTR,CDS,intron-Distal,intron-Proximal	4.52688	3.02457	HepG2	BCLAF1
chr12	9096391	9096507	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.00856	5.46976	K562	UCHL5
chr12	9094506	9094537	-	3'-UTR,CDS,intron-Distal	4.24466	3.77218	HepG2	SND1
chr12	9098829	9098925	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.11091	4.24993	HepG2	PPIG
chr12	9098004	9098069	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.95585	3.80193	HepG2	GRWD1
chr12	9096075	9096126	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.33022	3.77917	HepG2	SND1
chr12	9094296	9094412	-	3'-UTR,intron-Distal	3.23320	5.14024	HepG2	LARP4
chr12	9094985	9095106	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.93339	3.89619	HepG2	SRSF1
chr12	9096063	9096125	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.44034	7.80648	K562	YBX3
chr12	9098900	9099001	-	3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal	3.65076	12.41221	K562	DDX3X
chr12	9098137	9098200	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.66293	3.91876	HepG2	U2AF2
chr12	9098844	9098997	-	3'-UTR,CDS,intron-Distal,intron-Proximal	5.78624	13.97750	HepG2	DDX3X
chr12	9094980	9095051	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.61985	4.73026	K562	SRSF1
chr12	9095061	9095138	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.43517	6.57858	K562	SND1
chr12	9094432	9094490	-	3'-UTR,CDS,intron-Distal	3.54404	4.50521	HepG2	SND1
chr12	9101999	9102091	-	5'-UTR,intron-Distal	5.10091	7.13585	K562	PRPF8
chr12	9102125	9102247	-	5'-UTR,intron-Distal,intron-Proximal	6.33967	22.31810	K562	DDX3X
chr12	9102082	9102125	-	5'-UTR,intron-Distal	3.34101	6.12311	K562	DDX3X
chr12	9102006	9102091	-	5'-UTR,intron-Distal	3.79760	3.25631	HepG2	PRPF4
chr12	9099005	9099072	-	5'-UTR,intron-Distal,intron-Proximal	4.30045	6.99120	K562	AQR
chr12	9102090	9102120	-	5'-UTR,intron-Distal	4.49740	6.83552	HepG2	DDX3X
chr12	9102120	9102239	-	5'-UTR,intron-Distal,intron-Proximal	5.28551	70.45575	HepG2	DDX3X
chr12	9102135	9102194	-	5'-UTR,intron-Distal	5.12533	5.67454	HepG2	RPS3
chr12	9096410	9096469	-	CDS,intron-Distal,intron-Proximal	3.19490	4.49651	HepG2	SND1
chr12	9096385	9096398	-	CDS,intron-Distal,intron-Proximal	4.41611	6.99120	K562	AQR
chr12	9096436	9096495	-	CDS,intron-Distal,intron-Proximal	3.01757	3.17233	HepG2	BCLAF1
chr12	9096391	9096436	-	CDS,intron-Distal,intron-Proximal	4.58355	3.45943	HepG2	BCLAF1
chr12	9096385	9096477	-	CDS,intron-Distal,intron-Proximal	3.07367	4.94718	HepG2	PPIG
chr12	9101996	9102068	-	intron-Distal	5.44234	7.81430	K562	AQR
chr12	9102068	9102084	-	intron-Distal	5.10331	6.75320	K562	AQR
chr12	9096323	9096385	-	intron-Distal,intron-Proximal	4.14014	6.80869	K562	AQR
chr12	9100104	9100139	-	intron-Distal	4.18490	3.97018	HepG2	HNRNPM
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

eCLIP assay for M6PR is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for M6PR is not available on ENCORE database.
68 RBPs can affect the levels of M6PR.

The Knockdown/knockout RNA-Seq assay for M6PR is not available on ENCORE database.

68 RBPs can affect the gene expression of M6PR :

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
M6PR	ENSG00000003056.3	2116.73320	1641.31590	0.36690	3.37850	2.20010	HepG2	AATF
M6PR	ENSG00000003056.3	1593.67840	1970.98250	-0.30660	2.23470	1.33870	HepG2	ADAR
M6PR	ENSG00000003056.3	5692.83850	2716.14900	1.06750	17.76480	16.53920	HepG2	AKAP1
M6PR	ENSG00000003056.3	2765.85740	2247.39000	0.29940	2.11320	1.42170	HepG2	ASCC1
M6PR	ENSG00000003056.3	3635.14630	1891.23860	0.94260	20.23220	18.83810	HepG2	BOP1
M6PR	ENSG00000003056.3	2515.85320	1955.76570	0.36320	4.24430	3.31290	HepG2	CALR
M6PR	ENSG00000003056.3	983.03660	2135.17370	-1.11900	20.51070	18.63820	HepG2	CIRBP
M6PR	ENSG00000003056.3	2108.11350	1736.24450	0.27990	1.97790	1.38540	HepG2	CPSF6
M6PR	ENSG00000003056.3	907.03560	1311.42220	-0.53190	5.09140	3.69130	HepG2	CSTF2
M6PR	ENSG00000003056.3	2185.86340	1772.18390	0.30260	2.80160	1.88110	HepG2	DDX24
M6PR	ENSG00000003056.3	4062.52960	2601.87550	0.64270	7.91810	6.91070	HepG2	DDX3X
M6PR	ENSG00000003056.3	1641.54730	1967.12960	-0.26100	3.93320	3.18330	HepG2	DNAJC2
M6PR	ENSG00000003056.3	844.72120	1492.76900	-0.82140	9.97920	8.36970	HepG2	EIF3D
M6PR	ENSG00000003056.3	1749.72120	2958.97210	-0.75800	24.52080	22.55960	HepG2	EIF4G1
M6PR	ENSG00000003056.3	2021.41670	2834.51860	-0.48770	5.59800	4.46210	HepG2	EIF4G2
M6PR	ENSG00000003056.3	4166.96070	3251.97200	0.35760	7.22880	6.33390	HepG2	ETF1
M6PR	ENSG00000003056.3	2719.81940	2199.17250	0.30650	1.98540	1.32700	HepG2	FIP1L1
M6PR	ENSG00000003056.3	985.31040	1677.95820	-0.76810	12.25410	10.65870	HepG2	FUBP3
M6PR	ENSG00000003056.3	1251.75120	1968.12570	-0.65290	6.79460	5.81850	HepG2	GPKOW
M6PR	ENSG00000003056.3	2709.39630	2228.75080	0.28160	2.32870	1.68790	HepG2	HNRNPC
M6PR	ENSG00000003056.3	1913.80090	2946.82190	-0.62270	17.18290	15.59120	HepG2	HNRNPF
M6PR	ENSG00000003056.3	2498.58870	2214.01690	0.17430	1.88220	1.37250	HepG2	HNRNPU
M6PR	ENSG00000003056.3	1762.40820	2901.77080	-0.71940	15.05420	13.51150	HepG2	IGF2BP1
M6PR	ENSG00000003056.3	2810.95880	2259.03540	0.31530	2.42730	1.78980	HepG2	IGF2BP2
M6PR	ENSG00000003056.3	1939.78940	2409.98360	-0.31310	1.95090	1.41660	HepG2	MATR3
M6PR	ENSG00000003056.3	2592.70210	1779.99140	0.54250	7.92000	6.61620	HepG2	MSI2
M6PR	ENSG00000003056.3	1370.96450	1915.63620	-0.48260	2.58370	1.65110	HepG2	MTPAP
M6PR	ENSG00000003056.3	3538.53330	2974.14500	0.25060	2.66800	1.91890	HepG2	NOL12
M6PR	ENSG00000003056.3	1321.61970	1665.43440	-0.33360	2.51220	1.79840	HepG2	NSUN2
M6PR	ENSG00000003056.3	3029.74130	2191.51890	0.46720	10.08450	8.63700	HepG2	PARN
M6PR	ENSG00000003056.3	3476.71080	3013.75940	0.20610	3.46920	2.82000	HepG2	PUM1
M6PR	ENSG00000003056.3	1723.52890	3011.57470	-0.80520	19.57090	17.87930	HepG2	PUM2
M6PR	ENSG00000003056.3	1844.90540	2471.84680	-0.42200	6.21590	5.33150	HepG2	QKI
M6PR	ENSG00000003056.3	2810.04800	1994.87830	0.49420	2.51610	1.84250	HepG2	RAVER1
M6PR	ENSG00000003056.3	4519.25630	2718.08730	0.73340	22.84550	21.64810	HepG2	RBM22
M6PR	ENSG00000003056.3	791.78680	1807.36240	-1.19070	20.10780	17.43870	HepG2	RCC2
M6PR	ENSG00000003056.3	2164.62870	2540.01260	-0.23070	2.77840	2.23660	HepG2	NELFE
M6PR	ENSG00000003056.3	1950.49280	2365.64390	-0.27840	3.84470	3.13360	HepG2	RECQL
M6PR	ENSG00000003056.3	2399.10860	3174.56200	-0.40410	4.56330	3.71560	HepG2	RPLP0
M6PR	ENSG00000003056.3	1805.63900	1452.46770	0.31390	2.84690	2.22450	HepG2	RPS19
M6PR	ENSG00000003056.3	1723.59020	1971.68990	-0.19400	2.20630	1.61990	HepG2	SAFB2
M6PR	ENSG00000003056.3	2139.62020	2722.15960	-0.34740	7.29020	6.23560	HepG2	SLBP
M6PR	ENSG00000003056.3	3055.89020	2299.34050	0.41030	11.14810	9.99390	HepG2	SMN1
M6PR	ENSG00000003056.3	2739.77030	2068.52190	0.40540	2.00260	1.34310	HepG2	SNRNP70
M6PR	ENSG00000003056.3	3554.45470	3070.05120	0.21130	2.81510	2.31040	HepG2	SRFBP1
M6PR	ENSG00000003056.3	2983.15820	2480.24400	0.26630	3.89640	3.35900	HepG2	SRSF1
M6PR	ENSG00000003056.3	2089.29320	2895.18120	-0.47060	10.48130	9.27680	HepG2	SRSF7
M6PR	ENSG00000003056.3	2445.48890	2017.79700	0.27720	4.05640	3.41240	HepG2	SRSF9
M6PR	ENSG00000003056.3	1063.25570	1469.01560	-0.46640	3.05480	1.76330	HepG2	STAU1
M6PR	ENSG00000003056.3	3017.77340	2229.29610	0.43680	7.44280	6.59810	HepG2	TAF15
M6PR	ENSG00000003056.3	2660.91250	2170.55840	0.29380	4.45600	3.77470	HepG2	TRIM56
M6PR	ENSG00000003056.3	3260.58470	1881.32030	0.79330	13.13050	11.72480	HepG2	U2AF1
M6PR	ENSG00000003056.3	2249.93990	1873.70680	0.26390	3.70890	2.91920	HepG2	UPF1
M6PR	ENSG00000003056.3	2403.29450	1925.92370	0.31940	4.50280	3.20340	HepG2	UTP18
M6PR	ENSG00000003056.3	2891.10050	1808.99340	0.67630	21.41150	19.97780	HepG2	UTP3
M6PR	ENSG00000003056.3	3188.02380	2060.72170	0.62940	24.47490	23.25330	HepG2	ZNF622
M6PR	ENSG00000003056.3	2193.26490	1755.44580	0.32110	4.69630	3.99130	K562	AGGF1
M6PR	ENSG00000003056.3	3618.25820	2789.35580	0.37530	3.51690	2.87100	K562	AQR
M6PR	ENSG00000003056.3	1527.89130	1853.02050	-0.27830	3.08260	1.67860	K562	BCCIP
M6PR	ENSG00000003056.3	2143.51750	1477.43030	0.53680	5.80710	4.52940	K562	BOP1
M6PR	ENSG00000003056.3	950.28890	1727.03470	-0.86190	14.18510	11.66090	K562	CIRBP
M6PR	ENSG00000003056.3	1036.97840	1358.46090	-0.38960	4.22620	2.88420	K562	CSTF2
M6PR	ENSG00000003056.3	1499.17080	1199.74440	0.32130	2.79600	1.74820	K562	DDX3X
M6PR	ENSG00000003056.3	724.04380	1676.61780	-1.21140	13.89720	11.42200	K562	EIF3D
M6PR	ENSG00000003056.3	2006.96330	1598.41740	0.32830	2.66110	1.82300	K562	FMR1
M6PR	ENSG00000003056.3	2072.12810	1303.48890	0.66860	14.83510	13.54660	K562	FXR1
M6PR	ENSG00000003056.3	1118.36500	1569.68860	-0.48910	4.03500	2.28090	K562	GEMIN5
M6PR	ENSG00000003056.3	1206.68700	1542.69400	-0.35440	3.02380	1.82560	K562	HNRNPF
M6PR	ENSG00000003056.3	2949.88650	2391.97030	0.30240	2.93130	1.84070	K562	HNRNPL
M6PR	ENSG00000003056.3	1330.10510	1690.12210	-0.34560	3.30210	2.28300	K562	MATR3
M6PR	ENSG00000003056.3	5065.07640	3870.79840	0.38790	4.55360	2.60820	K562	NOL12
M6PR	ENSG00000003056.3	1956.24870	1523.59430	0.36050	3.09880	2.30430	K562	PRPF8
M6PR	ENSG00000003056.3	4606.92270	3861.19170	0.25470	2.10100	1.38930	K562	PUF60
M6PR	ENSG00000003056.3	4899.89380	4106.71600	0.25470	2.94920	1.84400	K562	PUM1
M6PR	ENSG00000003056.3	2759.28430	4024.04130	-0.54440	12.06940	10.06580	K562	PUM2
M6PR	ENSG00000003056.3	2218.09200	1811.54280	0.29200	2.10770	1.62120	K562	PUS1
M6PR	ENSG00000003056.3	626.61320	1413.09920	-1.17320	25.70320	22.79600	K562	RCC2
M6PR	ENSG00000003056.3	1260.51780	2246.43780	-0.83360	22.95350	20.81840	K562	SF3A3
M6PR	ENSG00000003056.3	1072.48040	1339.59850	-0.32080	2.30760	1.38920	K562	SRFBP1
M6PR	ENSG00000003056.3	2262.80740	1612.91880	0.48830	6.67810	5.58830	K562	SRSF1
M6PR	ENSG00000003056.3	1976.12780	1632.46640	0.27550	1.92500	1.32840	K562	TARDBP
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for M6PR is not available on ENCORE database.

11 RBPs can affect the splicing of M6PR :

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	M6PR	ENSG00000003056.3	chr12	-	9096396	9096506			9095891	9096131	9098013	9098075	-0.12900	0.00000	0.00000	excluded	K562	SF3B4
SE	M6PR	ENSG00000003056.3	chr12	-	9096396	9096531			9096000	9096131	9098013	9098075	-0.06100	0.00406	0.03920	excluded	K562	AQR
SE	M6PR	ENSG00000003056.3	chr12	-	9096023	9096131			9092960	9094536	9096396	9096482	-0.10100	0.00058	0.04740	excluded	K562	SUPV3L1
A3SS	M6PR	ENSG00000003056.3	chr12	-	9096023	9096180			9096023	9096131	9096396	9096506	0.07200	0.00003	0.00435	longer	K562	AGGF1
A3SS	M6PR	ENSG00000003056.3	chr12	-	9096023	9096180			9096023	9096131	9096396	9096506	0.05300	0.00088	0.07038	longer	K562	AKAP8L
A3SS	M6PR	ENSG00000003056.3	chr12	-	9092958	9094536			9092958	9093465	9095011	9095138	-0.06300	0.00034	0.07393	shorter	HepG2	NCBP2
A3SS	M6PR	ENSG00000003056.3	chr12	-	9095011	9095205			9095011	9095138	9096000	9096131	0.08000	0.00000	0.00000	longer	K562	AQR
A3SS	M6PR	ENSG00000003056.3	chr12	-	9098885	9099122			9098885	9099001	9102083	9102206	0.07100	0.00016	0.00136	longer	K562	AQR
A3SS	M6PR	ENSG00000003056.3	chr12	-	9096396	9096612			9096396	9096506	9098013	9098075	0.09700	0.00000	0.00000	longer	K562	AQR
A3SS	M6PR	ENSG00000003056.3	chr12	-	9096023	9096180			9096023	9096131	9096396	9096506	0.10700	0.00000	0.00001	longer	K562	PUS1
A3SS	M6PR	ENSG00000003056.3	chr12	-	9096023	9096180			9096023	9096131	9096396	9096506	0.07300	0.00001	0.00479	longer	K562	UTP18
A3SS	M6PR	ENSG00000003056.3	chr12	-	9096023	9096180			9096023	9096131	9096396	9096506	0.11200	0.00000	0.00005	longer	K562	RBM15
MXE	M6PR	ENSG00000003056.3	chr12	-	9095011	9095138	9096396	9096506	9092960	9094536	9098013	9098180	0.08600	0.00027	0.00810	1included	HepG2	FTO
MXE	M6PR	ENSG00000003056.3	chr12	-	9095011	9095138	9096396	9096506	9092960	9094536	9098013	9098180	-0.09300	0.00773	0.05134	2included	K562	AQR
MXE	M6PR	ENSG00000003056.3	chr12	-	9096396	9096506	9098013	9098180	9096000	9096131	9098824	9099001	-0.16000	0.00001	0.00016	2included	HepG2	U2AF2
MXE	M6PR	ENSG00000003056.3	chr12	-	9095011	9095138	9096023	9096131	9092960	9094536	9098013	9098180	0.05500	0.00103	0.02486	1included	K562	SUPV3L1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

M6PR

General Information

Functions

Localization

Domains (AlphaFold: M6PR)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for M6PR is not avaliable on ENCORE database.

17 proteins are bound to M6PR RNA:

eCLIP assay for M6PR is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for M6PR is not available on ENCORE database.

68 RBPs can affect the gene expression of M6PR :

The Knockdown/knockout RNA-Seq assay for M6PR is not available on ENCORE database.

11 RBPs can affect the splicing of M6PR :

The Knockdown/knockout RNA-Seq assay for M6PR is not avaliable on ENCORE database.