AATF

General Information

Gene Name       : AATF
Gene ID             : ENSG00000275700.4
Essential Gene : Yes

Functions

Localization(RBPImage: AATF)

Domains (AlphaFold: AATF)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878AATFENSG00000275700.459.8359.1859.50ENCSR000AEF
HepG2AATFENSG00000275700.441.0943.6042.34ENCSR985KAT
K562AATFENSG00000275700.491.1289.4190.27ENCSR000AEO

Assays

3 Released experiments are available on ENCORE database.

Assay TypeExp_NameENCODE IDTarget labelBiosampleStatusLinked AntibodyControlsMethodNote
eCLIPeCLIP: 511ENCSR819XBTAATFK562ReleasedENCAB064GNRENCSR290JPJ  
knockdown followed by RNA-seq AATF-BGKLV13-K562ENCSR973QSVAATFK562ReleasedENCSR815CVQ   shRNAKD% = 57.5,42.0
knockdown followed by RNA-seq AATF-BGHLV14-HepG2ENCSR424YSVAATFHepG2ReleasedENCSR003EKR   shRNAKD% = 77.5,81.1






  eCLIP  
  RBP    Exp_UID    Cell_Line    ENCODE_ACCESSION    Control_ENCODE_ACCESSION    ENCODE_Antibody_ID    Antibody    Lot_num    Status    Project  
AATF511K562ENCSR819XBTENCSR290JPJENCAB064GNRA301-032A1ReleasedENCODE4


  Antibody Validation  
  GeneName    Antibody_DCC_ID    Product_ID    Lot_ID    Phosphate    HepG2 Primary Validation    K562 Primary Validation    HepG2 Secondary Validation    K562 Secondary Validation  
AATFENCAB064GNRA301-032A1Released, ENCODE3Released, ENCODE3BGHLV14-3, Released, ENCODE3BGKLV13-13, Released, ENCODE3


  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
AATFK562shRNAENCSR973QSVENCSR815CVQAATF_BGKLV13_13,AATF_BGKLV13_14NT_BGKLV13_1,NT_BGKLV13_257.5,42.0ReleasedENCODE3
AATFHepG2shRNAENCSR424YSVENCSR003EKRAATF_BGHLV14-3,AATF_BGHLV14-4NT_BGHLV14-1_1,NT_BGHLV14-2_177.5,81.1ReleasedENCODE3


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  
    AATF: Click to RBP Image Database
  • Nuclei
  • Nucleolus
  • Cytoplasm
  • Cytosolic












    • RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela
    AATFProduct_ID: A301-032A
    Lot_ID: 1
    Source: Bethyl Labs
    Target Name: AATF-human    		 HepG2_Bethyl_A301-032A_1_AATF.png<br>Caption: IP-Western Blot analysis of HepG2 whole cell lysate using AATF specific antibody. Lane 1 is 1% of twenty million whole cell lysate input and lane 2 is 25% of IP enrichment using rabbit normal IgG (lanes under 'IgG'). Lane 3 is 1% of twenty million whole cell lysate input and lane 4 is 10% IP enrichment using rabbit polyclonal anti-AATF antibody (lanes under 'AATF').
    		 AATF_Secondary_Western.png<br>Caption: Western blot following shRNA against AATF in K562 and HepG2 whole cell lysate using AATF specific antibody. Lane 1 is a ladder, lane 2 is K562 non-targeting control knockdown, lane 2 and 3 are two different shRNAs against AATF. Lanes 5-7 follow the same pattern, but in HepG2. AATF protein appears as the green band, GAPDH serves as a control and appears in red.
    		 K562_Bethyl_A301-032A_1_AATF.png<br>Caption: IP-Western Blot analysis of K562 whole cell lysate using AATF specific antibody. Lane 1 is 1% of twenty million whole cell lysate input and lane 2 is 25% of IP enrichment using rabbit normal IgG (lanes under 'IgG'). Lane 3 is 1% of twenty million whole cell lysate input and lane 4 is 10% IP enrichment using rabbit polyclonal anti-AATF antibody (lanes under 'AATF').
    		 AATF_Secondary_Western.png<br>Caption: Western blot following shRNA against AATF in K562 and HepG2 whole cell lysate using AATF specific antibody. Lane 1 is a ladder, lane 2 is K562 non-targeting control knockdown, lane 2 and 3 are two different shRNAs against AATF. Lanes 5-7 follow the same pattern, but in HepG2. AATF protein appears as the green band, GAPDH serves as a control and appears in red.








    RNA Targets
    • AATF protein binds to 1,014 RNA regions.  





    Proteins bound to RNA
    • AATF RNA is bound by 24 proteins.  






    AATF protein has 1,014 RNA targets:

    Only display 100 entries as example. Please click "View All" button to see all 1,014 entries.     

    RBP Chr Start End Strand log2(fold change) -log(p-value) Cell Line Matched Gene Matched Area
    AATFchr20307185307218-5.116777.10995K562RP5-1103G7.4intron-Distal
    AATFchr2207026635207026668+5.4032346.22241K562EEF1B2intron-Distal,intron-Proximal
    AATFchr11811769811793+4.56863400.00000K562RPLP2intron-Distal
    AATFchr72350875023508814-4.257594.15782K562IGF2BP3intron-Distal
    AATFchr5111497290111497306+3.90438400.00000K562EPB41L4A-AS1intron-Distal,intron-Proximal
    AATFchr177612465676124709-3.125846.03850K562TMC65'-UTR,intron-Distal
    AATFchr63180306431803067+6.94103400.00000K562C6orf485'-UTR,intron-Distal,intron-Proximal
    AATFchr99505480295054829-3.4657184.31088K562IARSintron-Distal
    AATFchr156679519466795203-5.29646400.00000K562RPL4intron-Distal
    AATFchr171712020217120296-3.2550910.05781K562FLCN, RP11-45M22.4intron-Distal,intron-Proximal
    AATFchr19942622942669+3.496276.18699K562ARID3Aintron-Distal
    AATFchr1173833531173833539-3.23131400.00000K562GAS5intron-Distal,intron-Proximal
    AATFchr31590081415900889-4.0472510.88532K562ANKRD28CDS,intron-Distal
    AATFchr14264335542643425-3.9433714.03212K562FOXJ33'-UTR,intron-Distal
    AATFchr29755997497560041-4.1500365.48593K562FAM178Bintron-Distal
    AATFchr213873982238739871+3.929528.89989K562DYRK1Aintron-Distal
    AATFchr1911656231165686-6.3642723.75120K562SBNO2intron-Distal
    AATFchr1173834765173834823-3.36333400.00000K562GAS5intron-Distal,intron-Proximal
    AATFchr12816090728160955+3.7755112.85589K562PPP1R8intron-Distal
    AATFchr28636308686363115+4.08602400.00000K562PTCD3intron-Distal
    AATFchr172705045027050491+3.9648754.76419K562RPL23Aintron-Distal,intron-Proximal
    AATFchr31341912813419201-6.9261843.50916K562NUP210intron-Distal,intron-Proximal
    AATFchr201794357517943587-3.3890045.28527K562OVOL2, SNX5intron-Distal
    AATFchr31346166713461755-3.145063.90555K562NUP2105'-UTR,CDS,intron-Distal
    AATFchr1266195996619613+3.85073400.00000K562NCAPD2intron-Distal
    AATFchr194773191247731953-3.5193711.67491K562BBC3intron-Distal
    AATFchr9139621205139621227-4.11545400.00000K562SNHG7intron-Distal
    AATFchr9140668781140668845+6.572277.46810K562EHMT1intron-Distal
    AATFchr11977857419778650-3.364756.18699K562CAPZBintron-Distal
    AATFchr139200097392001015+3.059638.22129K562MIR17HGintron-Distal
    AATFchr192891863028918725-4.7462323.64933K562AC005307.1intron-Distal
    AATFchr194825915848259220+3.25516400.00000K562GLTSCR2intron-Distal,intron-Proximal
    AATFchr29753389797533942-4.078939.99368K562SEMA4Cintron-Distal
    AATFchr2203156098203156109+5.87803400.00000K562NOP58intron-Distal
    AATFchr12890527328905283-5.4289779.19470K562SNHG12intron-Distal
    AATFchr5111497256111497266+3.68559400.00000K562EPB41L4A-AS1intron-Distal
    AATFchr7932728932818+9.2359469.25778K562GET4, SUN1intron-Distal
    AATFchr176222348562223513+3.49418400.00000K562SNORA76intron-Distal,intron-Proximal
    AATFchr11496998497034-4.607817.41259K562RNH1intron-Distal
    AATFchr144558008945580175+4.761537.75307K562PRPF39intron-Distal,intron-Proximal
    AATFchr3160232722160232730-4.7256180.81040K562KPNA4intron-Distal
    AATFchr1914096941409738+4.177909.69181K562DAZAP1intron-Distal
    AATFchr4850236850358-7.0722715.66293K562GAKintron-Distal
    AATFchr12124917670124917780-5.585275.27957K562NCOR2intron-Distal
    AATFchr14105628813105628875-6.88523400.00000K562RP11-44N21.4, JAG2intron-Distal
    AATFchr9137232963137233021+5.377754.55917K562RXRAintron-Distal
    AATFchr63180485631804874+3.72186400.00000K562C6orf485'-UTR,intron-Distal
    AATFchr194127116641271210+6.5491586.16054K562SNRPA3'-UTR
    AATFchr19725620497256291+3.6815910.14102K562PTBP2intron-Distal
    AATFchr171634283216342866+4.9332745.03688K562C17orf76-AS1intron-Distal,intron-Proximal
    AATFchr12756122127561285+3.709884.89463K562WDTC15'-UTR
    AATFchr1622050542205060-4.65994400.00000K562RP11-304L19.5intron-Distal
    AATFchr194188345941883515+3.557406.51841K562CTC-435M10.3, TMEM91intron-Distal
    AATFchr158944448689444559-6.9335029.45135K562MFGE8intron-Distal
    AATFchr48381700583817065-7.88774114.59674K562SEC31A, THAP9-AS1intron-Distal,intron-Proximal
    AATFchr11638126638206+4.003524.99339K562DRD4intron-Distal
    AATFchr11811712811721+4.31830400.00000K562RPLP2intron-Proximal
    AATFchr2232325080232325086-4.4668255.84728K562NCLintron-Distal,intron-Proximal
    AATFchr31341542513415489-5.3263512.72968K562NUP210intron-Distal,intron-Proximal
    AATFchr119346416593464174-3.19961400.00000K562TAF1D3'-UTR,intron-Distal
    AATFchr116803176968031878-5.266557.10995K562C11orf24intron-Distal
    AATFchr1183441822183441994+4.493069.79246K562SMG7intron-Distal,intron-Proximal
    AATFchr1249151845249151950-3.3795613.08078K562ZNF6925'-UTR,intron-Distal,intron-Proximal
    AATFchr191056344410563499+6.031816.87822K562PDE4Aintron-Distal
    AATFchr173390067733900772+5.15877400.00000K562RP11-1094M14.11intron-Distal
    AATFchr1738399653840050-4.411316.13272K562ATP2A3intron-Distal
    AATFchr31590074115900796-3.465116.11374K562ANKRD28intron-Distal
    AATFchr7158703667158703804+4.5941219.59091K562WDR60intron-Distal
    AATFchr1614283801428416-3.813114.89463K562UNKLintron-Distal
    AATFchr35272292852722967+5.474075.03841K562GNL3intron-Distal,intron-Proximal
    AATFchr168904250489042536-4.257595.46507K562CBFA2T3intron-Distal
    AATFchr142377105623771076+7.5035218.19761K562BCL2L2intron-Distal
    AATFchr116262045162620464-4.22232400.00000K562SNHG1intron-Distal,intron-Proximal
    AATFchr201794351917943575-3.61202400.00000K562SNX5, OVOL2intron-Distal
    AATFchr116262042662620438-3.81975400.00000K562SNHG1intron-Distal
    AATFchr2105471753105471759+4.8102910.30629K562RP11-13J10.1intron-Distal
    AATFchr35153388751533966-4.517808.60314K562VPRBP5'-UTR,intron-Distal
    AATFchr2026373132637322+5.56426400.00000K562NOP56intron-Distal,intron-Proximal
    AATFchr168896113488961171-6.8862914.16137K562CBFA2T3intron-Distal
    AATFchr8650415650451-5.831209.57216K562ERICH1intron-Distal
    AATFchr201794346617943471-4.69425400.00000K562SNX5, OVOL2intron-Distal
    AATFchr19942296942333+4.411317.75307K562ARID3Aintron-Distal
    AATFchr14105625398105625440-4.531818.94227K562JAG2, RP11-44N21.4intron-Distal
    AATFchr13114268538114268635+6.435499.68371K562TFDP1intron-Distal
    AATFchr1922706802270745+3.7736962.22351K562OAZ1intron-Distal,intron-Proximal
    AATFchr194999417149994190+3.78019400.00000K562RPL13Aintron-Proximal
    AATFchr168895752188957614-3.677138.12643K562CBFA2T3intron-Distal
    AATFchr72289623122896250+5.0643614.97969K562AC005682.5intron-Proximal
    AATFchr7148523058148523127-3.318438.48689K562EZH2intron-Distal
    AATFchr172704759627047618+6.12271400.00000K562RPL23A5'-UTR,intron-Distal
    AATFchr9139621236139621259-4.10007400.00000K562SNHG7intron-Distal
    AATFchr8145693905145693974+4.4503111.83272K562KIFC2CDS,intron-Proximal
    AATFchr7932948932985+8.1043433.84307K562GET4, SUN1intron-Distal
    AATFchr63180303931803060+5.4577950.18965K562C6orf48intron-Distal,intron-Proximal
    AATFchr1977050387705142+5.8695961.04129K562CTD-3214H19.4, STXBP2intron-Distal
    AATFchr204789548047895497+4.70409400.00000K562ZFAS1intron-Distal
    AATFchr1911733581173412-5.181596.22228K562SBNO2intron-Distal
    AATFchr112765371276601-6.8647526.60905K562DVL1intron-Distal
    AATFchr116453394164533988-3.418564.23470K562SF1intron-Distal
    AATFchr2132044171132044230+3.174045.21378K562PLEKHB2intron-Distal




    24 proteins are bound to AATF RNA:

    Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
    chr173534583135345910+3'-UTR,CDS4.995616.76175HepG2PPIG
    chr173534582635345926+3'-UTR,CDS3.5478312.07018K562UCHL5
    chr173541398635414042+3'-UTR4.570905.42839K562PABPC4
    chr173531108935311229+5'-UTR,CDS,intron-Proximal3.013445.53494HepG2BCLAF1
    chr173530634035306376+5'-UTR3.720584.40383K562UCHL5
    chr173530638935306451+5'-UTR,CDS3.103916.35635K562UCHL5
    chr173530634535306458+5'-UTR,CDS5.280607.80708K562FXR2
    chr173530634535306431+5'-UTR,CDS3.440584.02244HepG2NCBP2
    chr173530638935306465+5'-UTR,CDS3.114144.18274K562XRCC6
    chr173531106635311140+5'-UTR,CDS,intron-Proximal4.404304.01763HepG2GRWD1
    chr173530635935306429+5'-UTR,CDS4.198834.94878HepG2GRWD1
    chr173530626935306370+5'-UTR3.332029.97831K562DDX3X
    chr173531114035311208+5'-UTR,CDS,intron-Proximal4.288643.34184HepG2GRWD1
    chr173537630835376365+CDS3.437703.59112HepG2PPIG
    chr173531051435310595+CDS,intron-Distal3.9751214.58259K562UCHL5
    chr173530651535306562+CDS,intron-Proximal4.699634.65563K562AQR
    chr173531018535310202+CDS,intron-Distal,intron-Proximal4.483404.77252K562ZNF622
    chr173531106935311121+CDS,intron-Proximal3.317683.04935K562ZNF800
    chr173531044635310592+CDS,intron-Distal3.321419.03865HepG2BCLAF1
    chr173531020935310347+CDS,intron-Distal4.0367215.80579K562UCHL5
    chr173531037935310512+CDS,intron-Distal4.757166.00552HepG2G3BP1
    chr173531039435310527+CDS,intron-Distal3.615709.56057K562TRA2A
    chr173534654535346653+CDS,intron-Proximal4.070593.79347HepG2GRWD1
    chr173531048735310536+CDS,intron-Distal4.611046.94741K562ZNF622
    chr173531037435310514+CDS,intron-Distal5.9281027.74779K562UCHL5
    chr173531039835310487+CDS,intron-Distal3.4045710.12596K562ZNF622
    chr173531037835310497+CDS,intron-Distal4.000079.30666K562PUM1
    chr173531038135310533+CDS,intron-Distal3.841834.14811HepG2FXR2
    chr173532891135328983+intron-Distal3.926123.06194K562ILF3
    chr173540505835405209+intron-Distal4.111193.53404K562HNRNPM
    chr173532301335323059+intron-Distal3.999803.45817K562MATR3
    chr173533901435339064+intron-Distal3.211803.26015K562PTBP1
    chr173531499735315063+intron-Distal4.343323.42734K562PTBP1
    chr173531464835314706+intron-Distal3.414544.23286HepG2QKI
    chr173540407035404138+intron-Distal4.707635.63362K562AGGF1
    chr173535055935350640+intron-Distal3.748373.03891HepG2PTBP1
    chr173532739535327461+intron-Distal4.379574.07991K562ILF3
    chr173535055535350617+intron-Distal3.817747.33240HepG2PCBP2
    chr173535719835357285+intron-Distal,intron-Proximal4.111723.12651K562SAFB2
    chr173531479535314875+intron-Distal4.157256.78885HepG2QKI
    chr173536052635360621+intron-Distal3.971524.16015K562SAFB2
    chr173535798735358098+intron-Distal4.398704.56270K562SAFB2
    chr173537941135379488+intron-Distal3.862046.42186K562TARDBP
    ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




    No autoregularoty interactions between protein AATF and its RNA.



    Diffrential Expression
    • 2,459 differentially expressed genes after Knockdown/Knockout AATF protein.  





    • 82 RBPs can affect the levels of AATF.  







    2,459 differentially expressed genes after Knockdown/Knockout AATF protein :

    Only display 100 entries as example. Please click "View All" button to see all 2,459 entries.     

    Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
    NIPAL3ENSG00000001461.12333.46170231.348700.527402.754801.68520HepG2AATF
    ANKIB1ENSG00000001629.51134.04330882.348600.362002.689801.63320HepG2AATF
    CYP51A1ENSG00000001630.111758.949302724.78270-0.631409.634807.79690HepG2AATF
    LASP1ENSG00000002834.136595.745105289.611600.318303.252802.09720HepG2AATF
    M6PRENSG00000003056.32116.733201641.315900.366903.378502.20010HepG2AATF
    CASP10ENSG00000003400.10813.04350556.807400.546104.770603.39670HepG2AATF
    TFPIENSG00000003436.1010561.386706826.554800.6295011.432909.46050HepG2AATF
    SLC7A2ENSG00000003989.123552.776905035.57720-0.503207.083505.45580HepG2AATF
    ARF5ENSG00000004059.6413.75910634.89620-0.617705.108903.69230HepG2AATF
    ARHGAP33ENSG00000004777.1461.75380158.71760-1.361907.036305.41340HepG2AATF
    UPF1ENSG00000005007.8844.103701328.01250-0.653802.731101.66570HepG2AATF
    FBXL3ENSG00000005812.6188.49300336.21470-0.834905.981304.46600HepG2AATF
    ITGALENSG00000005844.1321.9169065.22200-1.573304.104902.82430HepG2AATF
    ZFXENSG00000005889.11359.65260698.25120-0.9571011.572109.59130HepG2AATF
    ASB4ENSG00000005981.8281.8541070.637601.9963019.5613017.13920HepG2AATF
    GDE1ENSG00000006007.71761.507201302.487800.435404.316903.00490HepG2AATF
    AP2B1ENSG00000006125.124633.564203739.554000.309202.986101.87800HepG2AATF
    CX3CL1ENSG00000006210.61185.934401648.58380-0.475204.931403.54010HepG2AATF
    MAP3K9ENSG00000006432.11584.35830410.072700.510903.735002.49960HepG2AATF
    RALAENSG00000006451.3692.70000495.634800.482903.521602.32170HepG2AATF
    BAIAP2L1ENSG00000006453.9752.88380561.551800.422903.076001.95270HepG2AATF
    JHDM1DENSG00000006459.61899.136101549.309400.293602.359601.36630HepG2AATF
    ALDH3B1ENSG00000006534.1176.35270126.07550-0.723502.277901.30380HepG2AATF
    IFRD1ENSG00000006652.9651.06630423.674900.619705.154103.73050HepG2AATF
    E2F2ENSG00000007968.6126.51460192.23820-0.603602.291901.31370HepG2AATF
    CYB561ENSG00000008283.1115.4581040.26400-1.381102.337201.34830HepG2AATF
    PLEKHG6ENSG00000008323.11103.57060222.28540-1.101806.749205.15100HepG2AATF
    ST3GAL1ENSG00000008513.10766.041401308.85520-0.7728010.864408.93100HepG2AATF
    REV3LENSG00000009413.111440.623001018.859200.499605.189803.76020HepG2AATF
    MASP2ENSG00000009724.1268.85160120.92950-0.812602.577401.53930HepG2AATF
    MLXIPLENSG00000009950.11939.508102058.25300-1.131406.585205.00460HepG2AATF
    UQCRC1ENSG00000010256.61893.628102615.55190-0.466005.409603.95380HepG2AATF
    CD9ENSG00000010278.7348.68430205.525100.762505.273603.83050HepG2AATF
    NCAPD2ENSG00000010292.82276.187602885.52130-0.342202.991801.88310HepG2AATF
    SEMA3GENSG00000010319.2356.64120570.34550-0.677405.722104.23150HepG2AATF
    IDSENSG00000010404.13958.25870623.032500.621006.400404.83950HepG2AATF
    SCMH1ENSG00000010803.12730.68340949.24320-0.377502.795301.71810HepG2AATF
    FYNENSG00000010810.13995.93250660.538300.592306.071504.54680HepG2AATF
    HIVEP2ENSG00000010818.41505.80680957.114400.653708.562806.79780HepG2AATF
    CLCN6ENSG00000011021.17800.961101197.41270-0.580104.218802.92200HepG2AATF
    TSPAN9ENSG00000011105.7534.37530890.22540-0.736308.268106.53080HepG2AATF
    PTBP1ENSG00000011304.122012.390803258.12310-0.695105.064303.65700HepG2AATF
    SYT7ENSG00000011347.5132.61150217.21460-0.711903.297502.13430HepG2AATF
    LARS2ENSG00000011376.5559.83780747.42810-0.416902.963501.85930HepG2AATF
    TMEM159ENSG00000011638.6249.59690139.971200.834404.690603.32720HepG2AATF
    NR1H4ENSG00000012504.9302.08990708.67530-1.2301017.9607015.61190HepG2AATF
    ELOVL5ENSG00000012660.92573.693901923.902800.419704.523603.18480HepG2AATF
    CLDN11ENSG00000013297.6295.35410137.658601.101308.205506.47230HepG2AATF
    SLC25A39ENSG00000013306.11989.390801480.70750-0.581703.904402.64730HepG2AATF
    CLK1ENSG00000013441.111340.685101023.277200.389702.705301.64540HepG2AATF
    GPRC5AENSG00000013588.569.3596032.955801.073502.561101.52680HepG2AATF
    TACC3ENSG00000013810.14424.77540733.43890-0.788008.555606.79160HepG2AATF
    DPEP1ENSG00000015413.537.42730141.32460-1.916807.755606.07160HepG2AATF
    NPC1L1ENSG00000015520.10431.23420676.85840-0.650403.848202.59750HepG2AATF
    CHDHENSG00000016391.61705.678002551.91080-0.581208.082806.36170HepG2AATF
    SRCIN1ENSG00000017373.1189.62150176.93780-0.981302.322501.33730HepG2AATF
    WWTR1ENSG00000018408.102434.071801769.045600.460305.226203.79140HepG2AATF
    AGPSENSG00000018510.82948.863202335.105100.336603.127001.99390HepG2AATF
    CYP24A1ENSG00000019186.51029.90140256.996202.0026048.1861044.93850HepG2AATF
    CD74ENSG00000019582.10869.465901273.74820-0.550905.837604.33210HepG2AATF
    PLEKHB1ENSG00000021300.91759.978701434.886700.294502.289601.31220HepG2AATF
    SERPINB1ENSG00000021355.81686.918501331.863700.340802.851301.76570HepG2AATF
    CYP3A43ENSG00000021461.127.6058032.35420-2.088802.898101.80560HepG2AATF
    SLC7A9ENSG00000021488.811.3302050.91910-2.168005.208303.77660HepG2AATF
    C8BENSG00000021852.8234.84100332.91730-0.503502.589101.54840HepG2AATF
    ZDHHC6ENSG00000023041.7629.39580451.691900.478503.109201.97730HepG2AATF
    ABCC2ENSG00000023839.65115.108706424.92740-0.328903.428102.24370HepG2AATF
    EHD2ENSG00000024422.780.5329029.339201.456604.484103.14940HepG2AATF
    DEPDC1ENSG00000024526.12209.84950354.70440-0.757305.254003.81560HepG2AATF
    PHF20ENSG00000025293.111116.12340850.012800.392803.115301.98310HepG2AATF
    NCAPH2ENSG00000025770.14241.23230347.92810-0.528402.767101.69470HepG2AATF
    TOMM34ENSG00000025772.71242.58340866.815300.519403.790302.54760HepG2AATF
    RNASET2ENSG00000026297.112275.919303074.10830-0.433702.298401.31930HepG2AATF
    IFNGR1ENSG00000027697.82955.145501420.897401.0563024.4218021.78450HepG2AATF
    ARNTL2ENSG00000029153.10372.81670259.879200.520502.942901.84320HepG2AATF
    SLC39A9ENSG00000029364.7804.678901084.48280-0.430503.704302.47210HepG2AATF
    TFB1MENSG00000029639.61130.74420826.125800.452704.047402.77540HepG2AATF
    IKZF2ENSG00000030419.1251.1671017.693801.531903.274902.11550HepG2AATF
    SARSENSG00000031698.81481.098801184.221200.322602.499401.47580HepG2AATF
    RANBP3ENSG00000031823.10412.18260945.88890-1.1984019.7631017.33090HepG2AATF
    FUT8ENSG00000033170.12652.15000365.372400.835705.173303.74690HepG2AATF
    UHRF1ENSG00000034063.9609.23430861.98290-0.500704.216202.92080HepG2AATF
    MAP2K3ENSG00000034152.14521.27440693.79480-0.412502.769301.69580HepG2AATF
    TMSB10ENSG00000034510.44547.039403735.667900.283502.605901.56110HepG2AATF
    RNF19AENSG00000034677.71570.892501219.533500.365203.126801.99390HepG2AATF
    VCLENSG00000035403.121125.96650801.927100.489504.495803.15950HepG2AATF
    TIMP2ENSG00000035862.81988.487301054.435600.9151016.7507014.45350HepG2AATF
    MAT2BENSG00000038274.12465.75920679.53050-0.545004.473503.14000HepG2AATF
    VCANENSG00000038427.113176.194402314.787000.456304.819603.43980HepG2AATF
    CDH1ENSG00000039068.14384.69210838.10320-1.1234016.7103014.41690HepG2AATF
    PHLPP2ENSG00000040199.14595.45740436.987500.446302.867401.77970HepG2AATF
    AIFM2ENSG00000042286.10341.04140625.04990-0.874009.213007.40040HepG2AATF
    RETSATENSG00000042445.91062.527201425.61610-0.424103.902102.64530HepG2AATF
    PHKA2ENSG00000044446.71913.497503070.69530-0.6824011.056009.10440HepG2AATF
    DSG2ENSG00000046604.84706.706903634.590800.372804.023602.75440HepG2AATF
    CPENSG00000047457.917918.5692029950.21710-0.7411016.5641014.28530HepG2AATF
    DTNBP1ENSG00000047579.15214.49630139.520000.620402.658101.60480HepG2AATF
    C12orf4ENSG00000047621.7222.65160149.843200.571202.320201.33550HepG2AATF
    SCML1ENSG00000047634.102146.585201759.505500.286802.287701.31100HepG2AATF
    RRM2BENSG00000048392.71210.96080766.075500.660507.446005.78680HepG2AATF
    Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

    *: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
    **: "-log(0)" was displayed as "99999.99999".





    82 RBPs can affect the gene expression of AATF :

    Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
    AATFENSG00000108270.6196.05740592.95420-1.5966023.2534020.70470HepG2AATF
    AATFENSG00000108270.61132.86290764.782000.566809.884808.87990HepG2ACO1
    AATFENSG00000108270.6804.93310625.032000.364802.328001.41280HepG2ADAR
    AATFENSG00000108270.61522.86650807.559700.9150010.374709.40940HepG2AKAP1
    AATFENSG00000108270.6620.68460768.41470-0.308002.577101.83400HepG2AKAP8L
    AATFENSG00000108270.6942.76350668.159700.496603.706202.80150HepG2ASCC1
    AATFENSG00000108270.6391.68160632.39060-0.691105.420004.20250HepG2BCLAF1
    AATFENSG00000108270.61034.466901558.48860-0.591306.970606.06940HepG2BOP1
    AATFENSG00000108270.6991.93830634.806800.643806.007604.89890HepG2CIRBP
    AATFENSG00000108270.6963.978901430.77930-0.569705.800604.83850HepG2CPSF6
    AATFENSG00000108270.6823.16490640.966800.360803.163102.07490HepG2YBX3
    AATFENSG00000108270.61401.69690991.516100.499407.738906.76490HepG2CELF1
    AATFENSG00000108270.6974.06790715.599300.444802.618801.86390HepG2DDX55
    AATFENSG00000108270.6499.66970638.76690-0.354301.852601.35530HepG2EIF2S1
    AATFENSG00000108270.6865.52200530.014300.707406.742805.38090HepG2EIF3D
    AATFENSG00000108270.6820.10520617.988600.408103.268102.10340HepG2EIF3G
    AATFENSG00000108270.61152.10950687.368900.745005.725104.75910HepG2EIF4B
    AATFENSG00000108270.61278.335601051.790200.281302.933002.07550HepG2EIF4G1
    AATFENSG00000108270.6671.334701007.54060-0.585705.602504.46640HepG2EIF4G2
    AATFENSG00000108270.6643.95960491.156700.390702.415601.68000HepG2FUBP3
    AATFENSG00000108270.6994.544801621.90490-0.705607.419806.40130HepG2GPKOW
    AATFENSG00000108270.6508.55220635.39900-0.321301.864601.32230HepG2HNRNPA1
    AATFENSG00000108270.6504.14480706.76980-0.487403.578202.79750HepG2HNRNPC
    AATFENSG00000108270.6929.553201418.92190-0.610204.213903.34960HepG2HNRNPF
    AATFENSG00000108270.6877.78750669.295800.391102.608401.92840HepG2HNRNPK
    AATFENSG00000108270.6951.961901547.81320-0.701308.210207.18850HepG2HNRNPLL
    AATFENSG00000108270.6899.543301397.25790-0.635304.313003.42570HepG2IGF2BP1
    AATFENSG00000108270.6995.69650671.571300.568104.709903.84960HepG2IGF2BP2
    AATFENSG00000108270.6557.89440699.13630-0.325603.016901.95490HepG2KIF1C
    AATFENSG00000108270.6945.53040712.623800.407902.590801.95530HepG2MAGOH
    AATFENSG00000108270.61348.27220716.578600.9118010.449909.28470HepG2MATR3
    AATFENSG00000108270.6940.022201578.55720-0.747805.715804.29740HepG2MTPAP
    AATFENSG00000108270.6677.65610443.916800.610202.433501.61170HepG2PABPC1
    AATFENSG00000108270.6867.51680694.948200.319902.904102.03870HepG2PARN
    AATFENSG00000108270.6928.98700672.108700.466905.955105.11780HepG2PCBP1
    AATFENSG00000108270.6658.79930435.549100.596903.033801.44030HepG2PNPT1
    AATFENSG00000108270.6866.08260683.937600.340503.183002.60420HepG2PTBP1
    AATFENSG00000108270.6786.407701009.12850-0.359802.720002.12820HepG2PUF60
    AATFENSG00000108270.61267.372801070.457600.243501.881401.32240HepG2PUM2
    AATFENSG00000108270.61071.91790707.817400.598603.039002.30230HepG2RAVER1
    AATFENSG00000108270.62006.823401145.201200.809209.143708.32650HepG2RBM22
    AATFENSG00000108270.6790.80200591.346200.419202.381601.39880HepG2RCC2
    AATFENSG00000108270.6807.15120515.753900.646106.006305.14120HepG2RPS19
    AATFENSG00000108270.6671.67090459.278800.548303.285201.86390HepG2SART3
    AATFENSG00000108270.61549.194801072.647400.530203.726402.93950HepG2SF3A3
    AATFENSG00000108270.61153.996401532.03230-0.408803.626602.82780HepG2SF3B1
    AATFENSG00000108270.6777.81490967.62760-0.315003.244202.49480HepG2SLBP
    AATFENSG00000108270.61028.56300729.135100.496307.971606.96950HepG2SMN1
    AATFENSG00000108270.6225.391201704.65350-2.9190059.0152055.63900HepG2SNRNP70
    AATFENSG00000108270.61578.971601293.433100.287703.424002.88450HepG2SRFBP1
    AATFENSG00000108270.61317.92640743.196400.8264018.9219017.91630HepG2SRSF1
    AATFENSG00000108270.61173.36330996.385300.235802.154201.59380HepG2SRSF5
    AATFENSG00000108270.6966.418201393.95780-0.528503.411402.65000HepG2SRSF7
    AATFENSG00000108270.61335.215601133.149300.236602.565501.96200HepG2SUCLG1
    AATFENSG00000108270.6766.327501508.62520-0.9772016.1032014.60220HepG2TARDBP
    AATFENSG00000108270.6532.48060682.19620-0.357502.532202.05020HepG2TIAL1
    AATFENSG00000108270.61809.715301014.711900.8346012.9229011.53160HepG2U2AF1
    AATFENSG00000108270.6682.47470420.797600.697506.026104.89620HepG2UCHL5
    AATFENSG00000108270.61749.91290918.417700.9300023.4935022.00300HepG2UTP3
    AATFENSG00000108270.61314.745101046.219500.329504.720504.05450HepG2ZNF622
    AATFENSG00000108270.62612.883402037.691800.358602.437501.33670K562AARS
    AATFENSG00000108270.6545.528702043.45310-1.9053023.1811018.81460K562AATF
    AATFENSG00000108270.63415.450702886.262000.242803.409302.79180K562AGGF1
    AATFENSG00000108270.62499.150203003.26310-0.265102.180301.59790K562AKAP8L
    AATFENSG00000108270.62303.636303011.71510-0.386703.523302.53930K562BOP1
    AATFENSG00000108270.62673.827503202.37400-0.260202.443201.70250K562CPSF6
    AATFENSG00000108270.62072.701801723.559600.266002.726301.41600K562DDX27
    AATFENSG00000108270.67572.048204314.304000.8115035.8082033.73390K562DDX47
    AATFENSG00000108270.63897.584603231.872800.270103.529202.52260K562DKC1
    AATFENSG00000108270.62391.079701591.459800.5872011.465309.82380K562EIF3G
    AATFENSG00000108270.63795.792204595.41240-0.275803.686502.60260K562EIF4G2
    AATFENSG00000108270.63226.288103904.52120-0.275302.161401.40960K562FIP1L1
    AATFENSG00000108270.61910.869002761.59590-0.531305.658604.29930K562FTO
    AATFENSG00000108270.62427.883801625.195500.5790012.3868011.19830K562FXR1
    AATFENSG00000108270.62284.451303057.52450-0.420504.769403.73100K562GPKOW
    AATFENSG00000108270.61174.541602230.86060-0.925506.210105.35150K562HNRNPC
    AATFENSG00000108270.62758.129401865.307000.564205.645203.81920K562HNRNPK
    AATFENSG00000108270.61964.798602610.62560-0.410002.643201.73280K562KRR1
    AATFENSG00000108270.62473.882601963.106500.333503.308002.38220K562MAGOH
    AATFENSG00000108270.62325.690702984.46590-0.359803.719902.69430K562METAP2
    AATFENSG00000108270.62852.829103426.22300-0.264204.199503.22090K562MTPAP
    AATFENSG00000108270.62209.171701746.487800.338903.040302.01490K562PCBP2
    AATFENSG00000108270.63685.148404432.12660-0.266302.165501.44400K562PPIG
    AATFENSG00000108270.62823.324901762.383400.679809.806908.38720K562PRPF8
    AATFENSG00000108270.63209.839401907.359100.7508015.7887014.27010K562PTBP1
    AATFENSG00000108270.62592.861301828.358400.503906.027604.72520K562RBM22
    AATFENSG00000108270.62746.803101795.286000.613406.439705.18280K562RPS19
    AATFENSG00000108270.61819.844401510.977600.268202.382701.59130K562SF3B4
    AATFENSG00000108270.62993.826903848.44070-0.362308.934807.35730K562SRPK2
    AATFENSG00000108270.62720.579201869.965200.540808.318607.10060K562SRSF1
    AATFENSG00000108270.63510.304904686.06780-0.416803.936202.39880K562STAU1
    AATFENSG00000108270.63330.977302610.768800.351404.436503.39050K562SYNCRIP
    AATFENSG00000108270.63484.992504568.54990-0.390603.331101.78110K562TRIP6
    AATFENSG00000108270.61857.977801408.513000.399502.874301.75710K562U2AF1
    AATFENSG00000108270.61873.428001454.728800.364804.055703.08410K562U2AF2
    AATFENSG00000108270.63138.749804036.55460-0.362907.812006.67890K562UPF1
    AATFENSG00000108270.62932.985403453.96280-0.235902.089301.33030K562WDR3
    AATFENSG00000108270.63354.742503982.25400-0.247402.074301.33850K562ZC3H8
    Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

    *: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
    **: "-log(0)" was displayed as "99999.99999".





    5 alternative splicing events after Knockdown/Knockout AATF protein :

    Only display 100 entries as example. Please click "View All" button to see all 5 entries.     

    Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
    SEPPDPFENSG00000125534.5chr20+6215263662152716621521276215224762152864621532910.076000.000000.02980includedK562AATF
    SEANAPC16ENSG00000166295.4chr10+7398364573983814739758057397589673990123739901980.159000.000010.09468includedK562AATF
    SECENPEENSG00000138778.7chr4-1040609451040612361040595071040596061040614121040615710.503000.000000.00044includedK562AATF
    SESF1ENSG00000168066.16chr11-645409016454097764537768645378806454396964544098-0.061000.000010.09468excludedK562AATF
    SEVEGFAENSG00000112715.16chr6+437484684374859143746625437466554374969243749824-0.111000.000010.09860excludedK562AATF





    1 RBPs can affect the splicing of AATF :

    Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
    SEAATFENSG00000108270.6chr17+353888633538898235378232353783133541390035414171-0.057000.009140.07562excludedK562AQR

    *: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
    **: "-log(0)" was displayed as "99999.99999".





    No autoregularoty alternative splicing events between protein AATF and its RNA.