CAPZB

General Information

Gene Name       : CAPZB
Gene ID             : ENSG00000077549.17
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: CAPZB)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878CAPZBENSG00000077549.17258.27308.95283.61ENCSR000AEF
HepG2CAPZBENSG00000077549.17175.05179.13177.09ENCSR985KAT
K562CAPZBENSG00000077549.17186.87199.97193.42ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for CAPZB is not avaliable on ENCORE database.



Proteins bound to RNA
  • CAPZB RNA is bound by 47 proteins.  







eCLIP assay for CAPZB is not avaliable on ENCORE database.





47 proteins are bound to CAPZB RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr11966561019665646-3'-UTR,intron-Distal3.8874511.39016K562PABPC4
chr11966552619665569-3'-UTR,intron-Distal3.328663.56007K562DDX6
chr11966582219665868-3'-UTR,intron-Distal,intron-Proximal4.353713.15159HepG2LARP4
chr11966539419665577-3'-UTR,intron-Distal3.9955120.04423K562FAM120A
chr11966537119665412-3'-UTR,intron-Distal5.2907813.04183K562PABPC4
chr11966608819666125-3'-UTR,CDS,intron-Distal4.242863.79000HepG2U2AF2
chr11966589819665977-3'-UTR,intron-Distal3.8450121.57203K562PCBP1
chr11966551419665582-3'-UTR,intron-Distal4.461484.85626K562TARDBP
chr11966547919665587-3'-UTR,intron-Distal5.0640641.74201K562UPF1
chr11966590419665958-3'-UTR,intron-Distal5.0781425.42807K562IGF2BP2
chr11966572419665779-3'-UTR,intron-Distal,intron-Proximal3.3570015.89705K562IGF2BP2
chr11966534419665353-3'-UTR,intron-Distal4.539537.67996K562PABPC4
chr11966586119665904-3'-UTR,intron-Distal3.7253613.14804K562IGF2BP2
chr11966586819665985-3'-UTR,intron-Distal3.177698.41758HepG2LARP4
chr11966552019665557-3'-UTR,intron-Distal3.513063.69481K562UCHL5
chr11966530519665344-3'-UTR,intron-Distal,intron-Proximal5.5563617.42985K562PABPC4
chr11966549319665586-3'-UTR,intron-Distal5.2701832.05316HepG2SUB1
chr11966558719665655-3'-UTR,intron-Distal3.195969.18304K562UPF1
chr11966552819665575-3'-UTR,intron-Distal3.143543.27682HepG2LARP4
chr11966545019665574-3'-UTR,intron-Distal4.252293.87385HepG2AKAP1
chr11966608719666159-3'-UTR,CDS,intron-Distal3.643396.71722K562SF3B4
chr11966566919665719-3'-UTR,intron-Distal3.474559.18947HepG2PCBP2
chr11966540019665479-3'-UTR,intron-Distal4.7971923.90809K562UPF1
chr11966553119665579-3'-UTR,intron-Distal3.168003.80158K562NONO
chr11966580419665816-3'-UTR,intron-Distal,intron-Proximal3.074733.60832K562PABPC4
chr11966545319665564-3'-UTR,intron-Distal4.229344.25576HepG2PABPN1
chr11966551519665574-3'-UTR,intron-Distal4.079313.44758HepG2CSTF2T
chr11966543319665582-3'-UTR,intron-Distal5.4937524.27438HepG2UPF1
chr11966550319665582-3'-UTR,intron-Distal3.353614.06907HepG2GRSF1
chr11966569919665805-3'-UTR,intron-Distal,intron-Proximal3.929717.71063HepG2LARP4
chr11966590619665976-3'-UTR,intron-Distal4.8715948.76634HepG2PCBP2
chr11966572319665772-3'-UTR,intron-Distal,intron-Proximal3.6612816.26888HepG2PCBP2
chr11981192719812027-5'-UTR,CDS,intron-Distal,intron-Proximal3.105656.64128HepG2NCBP2
chr11981055419810636-5'-UTR,intron-Distal,intron-Proximal3.947917.00469K562NONO
chr11981192819812023-5'-UTR,CDS,intron-Distal,intron-Proximal3.059693.30907HepG2DDX3X
chr11981085619810911-5'-UTR,intron-Distal3.779034.71513K562NONO
chr11974618519746227-5'-UTR,CDS,intron-Distal4.1345517.85536K562YBX3
chr11981081019810890-5'-UTR,intron-Distal3.583504.76898K562CSTF2T
chr11981093719811021-5'-UTR,intron-Distal4.228158.40323K562NONO
chr11981077919810827-5'-UTR,intron-Distal4.370683.98553K562NONO
chr11981115719811193-5'-UTR,intron-Distal,intron-Proximal3.978753.99137K562NONO
chr11981079619810922-5'-UTR,intron-Distal5.439069.85717HepG2CSTF2T
chr11981192619812021-5'-UTR,CDS,intron-Distal,intron-Proximal4.4470313.76551K562DDX3X
chr11974622719746241-5'-UTR,CDS,intron-Distal3.586838.84704K562YBX3
chr11974617019746246-5'-UTR,CDS,intron-Distal,intron-Proximal5.6128831.12798K562DDX3X
chr11967169319671727-CDS,intron-Distal3.904303.80193HepG2GRWD1
chr11971201419712035-CDS,intron-Distal3.297437.37965K562YBX3
chr11971199719712080-CDS,intron-Distal,intron-Proximal4.7645222.55139K562LIN28B
chr11970514119705146-CDS,intron-Distal3.7865118.88897K562YBX3
chr11971207119712094-CDS,intron-Distal4.0271914.57262K562YBX3
chr11971201019712060-CDS,intron-Distal3.254043.80299HepG2GRWD1
chr11971211319712120-CDS,intron-Distal3.5883110.17500K562YBX3
chr11970510719705114-CDS,intron-Distal3.5524526.26167K562YBX3
chr11970505219705129-CDS,intron-Distal4.326097.21729HepG2RPS3
chr11970504219705136-CDS,intron-Distal3.8277411.79057HepG2G3BP1
chr11970511419705133-CDS,intron-Distal3.6626026.51032K562YBX3
chr11968404019684055-CDS,intron-Distal3.515819.18871K562YBX3
chr11966935219669394-CDS,intron-Distal,intron-Proximal3.870683.57432K562NONO
chr11967172419671795-CDS,intron-Distal,intron-Proximal4.2426116.86519K562SF3B4
chr11967173119671807-CDS,intron-Distal,intron-Proximal3.925243.84691HepG2SF3B4
chr11974615419746166-CDS,intron-Distal,intron-Proximal3.6471410.28466K562YBX3
chr11967171419671801-CDS,intron-Distal,intron-Proximal4.3150710.72196K562SMNDC1
chr11970505119705126-CDS,intron-Distal3.9906419.66774K562RPS3
chr11971209419712113-CDS,intron-Distal3.6241412.44872K562YBX3
chr11967092619670970-CDS,intron-Distal,intron-Proximal4.311916.59856K562SF3B4
chr11968317019683223-CDS,intron-Distal3.207234.77136HepG2PPIG
chr11968401119684040-CDS,intron-Distal,intron-Proximal4.8057041.06184K562YBX3
chr11970503219705047-CDS,intron-Distal,intron-Proximal3.796483.04123K562LIN28B
chr11971199919712014-CDS,intron-Distal3.082505.40086K562YBX3
chr11968397819684056-CDS,intron-Distal,intron-Proximal5.1030836.04843K562LIN28B
chr11968397719684010-CDS,intron-Distal,intron-Proximal5.0392438.68037K562YBX3
chr11967168019671739-CDS,intron-Distal,intron-Proximal3.927006.51752K562PABPC4
chr11967164019671711-CDS,intron-Distal,intron-Proximal4.9475020.98117HepG2PRPF8
chr11971196319712020-CDS,intron-Distal,intron-Proximal3.327995.90285HepG2PRPF8
chr11968308019683137-CDS,intron-Distal,intron-Proximal3.396365.06115HepG2PRPF8
chr11970513319705141-CDS,intron-Distal3.8670419.84518K562YBX3
chr11971199319712037-CDS,intron-Distal,intron-Proximal4.468965.23082K562DDX24
chr11968391419683963-CDS,intron-Distal,intron-Proximal3.588726.13978HepG2PPIG
chr11967168119671743-CDS,intron-Distal3.049376.48096HepG2G3BP1
chr11971203119712100-CDS,intron-Distal3.018205.39172HepG2G3BP1
chr11967091919670981-CDS,intron-Distal,intron-Proximal4.188773.56713HepG2SF3B4
chr11977857419778650-intron-Distal3.364756.18699K562AATF
chr11980951619809570-intron-Distal3.330935.59281K562HNRNPM
chr11980106919801128-intron-Distal5.359335.61339K562QKI
chr11975135019751454-intron-Distal3.850894.28420HepG2HNRNPM
chr11981021719810249-intron-Distal4.058413.07980HepG2HNRNPM
chr11981162219811673-intron-Distal3.983415.65933HepG2DDX59
chr11979616519796260-intron-Distal4.202413.91772K562TARDBP
chr11981141519811566-intron-Distal3.8377212.46969K562HNRNPK
chr11981144219811583-intron-Distal4.031059.68167HepG2DDX59
chr11981119819811249-intron-Distal,intron-Proximal4.909215.11777HepG2DDX59
chr11967093219670979-intron-Distal,intron-Proximal4.333024.08582K562SMNDC1
chr11980951819809602-intron-Distal4.958657.15660HepG2HNRNPM
chr11980472519804781-intron-Distal3.445594.08493K562HNRNPM
chr11970493719704996-intron-Distal,intron-Proximal4.064383.49003K562PRPF8
chr11967093019670974-intron-Distal,intron-Proximal4.005443.01321K562LSM11
chr11981177119811845-intron-Distal5.065705.59726K562GEMIN5
chr11977857219778672-intron-Distal4.700697.09127HepG2PRPF4
chr11974793719748007-intron-Distal3.919643.27946HepG2HNRNPM
chr11980153619801580-intron-Distal3.378413.90822HepG2HNRNPM
chr11980982619809873-intron-Distal4.313893.86368HepG2HNRNPM
chr11970248119702577-intron-Distal3.265135.34585K562CSTF2T
chr11980179619801842-intron-Distal4.093613.60235HepG2HNRNPM
chr11975486819754920-intron-Distal3.623613.15106HepG2HNRNPC
chr11979562819795721-intron-Distal3.951144.35255HepG2PCBP2
chr11980473319804782-intron-Distal4.097303.01445K562EXOSC5
chr11980491719805000-intron-Distal3.421933.10641K562HNRNPM
chr11975721819757285-intron-Distal3.151343.11000HepG2HNRNPM
chr11970250619702587-intron-Distal5.366916.66343K562FMR1
chr11967116419671198-intron-Distal3.698485.44908K562SF3B4
chr11975673819756779-intron-Distal3.678573.66782HepG2HNRNPM
chr11980146719801523-intron-Distal3.110263.36616K562NONO
chr11981125919811321-intron-Distal4.804675.59072HepG2HNRNPK
chr11980492319804980-intron-Distal3.350893.68481HepG2HNRNPM
chr11980406919804140-intron-Distal4.866786.10662K562HNRNPM
chr11981179919811832-intron-Distal4.263125.65933HepG2DDX59
chr11979622019796324-intron-Distal4.294645.34995K562EIF4G2
chr11981143519811523-intron-Distal3.725475.65979HepG2PTBP1
chr11981174019811799-intron-Distal4.764936.64417K562NONO
chr11981174219811830-intron-Distal3.401675.50444K562HNRNPK
chr11981174919811853-intron-Distal3.828118.84510HepG2CSTF2T
chr11979064919790740-intron-Distal4.877908.54663K562PTBP1
chr11981177019811834-intron-Distal3.534993.81620HepG2LARP4
chr11981147019811522-intron-Distal4.000483.27829HepG2MATR3
chr11980194419802050-intron-Distal4.9914330.21214HepG2XPO5
chr11980108319801125-intron-Distal4.5153915.69529HepG2QKI
chr11972298019723055-intron-Distal3.347643.01707K562SLTM
chr11978223419782290-intron-Distal4.441185.16513HepG2HNRNPM
chr11981141919811518-intron-Distal3.896753.33944K562MATR3
chr11981142519811531-intron-Distal5.358005.53421K562PCBP1
chr11977793119777992-intron-Distal3.840933.07008K562NONO
chr11981160119811664-intron-Distal3.582284.84707HepG2HNRNPK
chr11981144319811515-intron-Distal3.099553.80464HepG2HNRNPK
chr11981119319811299-intron-Distal,intron-Proximal4.7115911.74022K562NONO
chr11980952219809584-intron-Distal4.507025.12432K562EXOSC5
chr11981176919811815-intron-Distal4.591195.14122HepG2PCBP2
chr11968308119683128-intron-Distal,intron-Proximal4.973856.22530K562AQR
chr11980482819804877-intron-Distal4.158904.03833K562HNRNPM
chr11981122119811307-intron-Distal,intron-Proximal3.564374.10487K562HNRNPK
chr11976381819763899-intron-Distal3.216973.11000HepG2HNRNPM
chr11981117019811238-intron-Distal,intron-Proximal3.056434.68702K562TIA1
chr11981161519811679-intron-Distal3.280143.63710K562HNRNPK
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for CAPZB is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for CAPZB is not available on ENCORE database.

  • 75 RBPs can affect the levels of CAPZB.  








The Knockdown/knockout RNA-Seq assay for CAPZB is not available on ENCORE database.





75 RBPs can affect the gene expression of CAPZB :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
CAPZBENSG00000077549.132310.254102961.69370-0.358402.848901.89420HepG2ABCF1
CAPZBENSG00000077549.133018.678002240.105800.4302010.111809.09950HepG2ACO1
CAPZBENSG00000077549.132594.180202250.566300.204902.339101.62750HepG2AKAP8L
CAPZBENSG00000077549.132548.340503049.98500-0.259201.985401.47080HepG2BOP1
CAPZBENSG00000077549.133688.376402863.907600.364903.192902.36430HepG2CIRBP
CAPZBENSG00000077549.132649.592902239.541800.242503.859703.09960HepG2CKAP4
CAPZBENSG00000077549.133907.160003391.097000.204302.206701.62280HepG2CELF1
CAPZBENSG00000077549.132185.767603645.92610-0.7381031.7334029.75270HepG2DAZAP1
CAPZBENSG00000077549.132371.043902071.741500.194602.403901.62120HepG2DDX19B
CAPZBENSG00000077549.131325.240401965.82120-0.568907.314606.26370HepG2DDX21
CAPZBENSG00000077549.131399.625801945.12010-0.4748011.062409.85650HepG2DNAJC2
CAPZBENSG00000077549.132170.420502881.93180-0.409103.495602.83370HepG2EIF2S1
CAPZBENSG00000077549.132927.571903597.21910-0.297204.593103.55580HepG2EIF4G1
CAPZBENSG00000077549.132516.385203445.85380-0.453504.879603.81660HepG2EIF4G2
CAPZBENSG00000077549.132604.945002188.915100.250902.134101.40130HepG2EWSR1
CAPZBENSG00000077549.131101.306301882.57370-0.773508.682005.79660HepG2GRWD1
CAPZBENSG00000077549.131627.903801981.38000-0.283502.220601.63690HepG2HNRNPA1
CAPZBENSG00000077549.131843.480402203.87600-0.257601.968701.37290HepG2HNRNPC
CAPZBENSG00000077549.132627.681703399.62270-0.371607.070405.99280HepG2HNRNPF
CAPZBENSG00000077549.132791.252602189.308500.350306.208405.33080HepG2HNRNPU
CAPZBENSG00000077549.132721.164103347.65090-0.298903.445002.64380HepG2IGF2BP1
CAPZBENSG00000077549.134982.282403566.613800.482203.761402.79050HepG2LARP4
CAPZBENSG00000077549.132596.227203214.55150-0.308202.141401.56200HepG2MAGOH
CAPZBENSG00000077549.132756.731703615.31080-0.391205.647104.56510HepG2NOL12
CAPZBENSG00000077549.132227.544702946.56830-0.403603.325002.53780HepG2PABPC4
CAPZBENSG00000077549.132049.004603094.94570-0.5950016.4305015.15390HepG2PCBP1
CAPZBENSG00000077549.131288.763002141.62480-0.732705.880504.41300HepG2PCBP2
CAPZBENSG00000077549.132634.416703149.19250-0.257503.644503.03510HepG2PTBP1
CAPZBENSG00000077549.132485.137703663.73500-0.5600014.2572013.13130HepG2PUM1
CAPZBENSG00000077549.132674.617003410.71820-0.350704.966204.16550HepG2QKI
CAPZBENSG00000077549.132629.086003381.54340-0.363105.468304.80190HepG2RBM22
CAPZBENSG00000077549.132568.332903095.42150-0.269302.542101.89300HepG2RBM25
CAPZBENSG00000077549.132533.784803264.17500-0.365406.983606.06970HepG2RECQL
CAPZBENSG00000077549.132801.282803662.33030-0.386704.265003.44640HepG2RPLP0
CAPZBENSG00000077549.131932.687401538.215900.329303.005402.36820HepG2RPS19
CAPZBENSG00000077549.131724.529101949.70130-0.177101.910001.35770HepG2SAFB2
CAPZBENSG00000077549.133381.154502525.067200.421102.838302.15480HepG2SF3A3
CAPZBENSG00000077549.132206.385802998.51100-0.442603.781202.96790HepG2SF3B1
CAPZBENSG00000077549.132710.060803278.77060-0.274804.256703.54820HepG2SF3B4
CAPZBENSG00000077549.132842.365303309.40870-0.219503.278102.52520HepG2SLBP
CAPZBENSG00000077549.131326.371802109.16110-0.669205.561004.16790HepG2SMNDC1
CAPZBENSG00000077549.131778.265503336.33300-0.907808.796907.41150HepG2SNRNP70
CAPZBENSG00000077549.133972.497503422.304300.215003.124302.63020HepG2SRSF1
CAPZBENSG00000077549.132299.684203340.04090-0.5384014.2379012.87270HepG2SRSF7
CAPZBENSG00000077549.131310.555002784.20760-1.0871050.2615048.48500HepG2SRSF9
CAPZBENSG00000077549.131877.216302432.21130-0.373702.608001.36060HepG2SSRP1
CAPZBENSG00000077549.133332.296503875.39450-0.217803.353402.68190HepG2SUCLG1
CAPZBENSG00000077549.132268.055903076.03870-0.439607.713306.85310HepG2TAF15
CAPZBENSG00000077549.131994.734702826.52610-0.502807.577706.20870HepG2TIA1
CAPZBENSG00000077549.131390.267602146.32860-0.6265015.1458013.97520HepG2TRIM56
CAPZBENSG00000077549.132436.850702162.004600.172501.960601.43850HepG2UTP3
CAPZBENSG00000077549.132306.611902580.76360-0.162001.955001.37550HepG2ZC3H8
CAPZBENSG00000077549.135302.043803514.359300.5932019.9036018.49760K562AGGF1
CAPZBENSG00000077549.135080.897803861.802000.395704.678503.32010K562AKAP8
CAPZBENSG00000077549.135145.461403656.863100.492604.727903.86670K562AKAP8L
CAPZBENSG00000077549.133116.632904263.58760-0.452105.602004.81790K562AQR
CAPZBENSG00000077549.134611.852003836.954000.265303.509502.46920K562ATP5C1
CAPZBENSG00000077549.134315.501503546.259600.283102.172301.40580K562BOP1
CAPZBENSG00000077549.135239.316603934.965800.412907.345005.80180K562DKC1
CAPZBENSG00000077549.134761.061503572.267100.414308.004506.87740K562EIF2S2
CAPZBENSG00000077549.134389.540205504.74950-0.326606.006104.63940K562EIF4G2
CAPZBENSG00000077549.134982.407803251.243500.615809.580007.89710K562FIP1L1
CAPZBENSG00000077549.131447.774602243.25580-0.631805.431804.36500K562G3BP2
CAPZBENSG00000077549.131590.391502290.84020-0.526506.438003.51020K562GRWD1
CAPZBENSG00000077549.133812.040802674.266100.511305.051603.75000K562HNRNPM
CAPZBENSG00000077549.135895.782804407.895100.419504.824803.78300K562HSPD1
CAPZBENSG00000077549.134688.920203880.800500.272802.685001.87350K562KIF1C
CAPZBENSG00000077549.134976.393103714.917700.421705.078303.47500K562MAK16
CAPZBENSG00000077549.136010.677304347.483200.467207.178405.58120K562MBNL1
CAPZBENSG00000077549.134067.797803047.274800.416602.926502.01570K562NAA15
CAPZBENSG00000077549.134482.709402907.101700.624702.869801.85600K562PABPN1
CAPZBENSG00000077549.132059.512202855.60060-0.471505.854704.41610K562PCBP2
CAPZBENSG00000077549.135231.828803690.908200.503206.282304.96090K562PPIG
CAPZBENSG00000077549.135231.119806388.73850-0.288403.803702.53360K562PUM1
CAPZBENSG00000077549.136236.444603626.513000.782004.406903.74480K562PUS1
CAPZBENSG00000077549.134703.743503533.566600.412607.383106.44670K562RBM15
CAPZBENSG00000077549.134378.134502658.442800.719602.555601.41770K562SF1
CAPZBENSG00000077549.132578.358102043.957900.335003.092501.99390K562SRFBP1
CAPZBENSG00000077549.133484.001704020.20230-0.206503.395802.37150K562SRPK2
CAPZBENSG00000077549.132823.278002273.312700.312502.313701.46320K562TIAL1
CAPZBENSG00000077549.134795.439504216.719100.185402.432201.75760K562UPF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for CAPZB is not available on ENCORE database.





3 RBPs can affect the splicing of CAPZB :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SECAPZBENSG00000077549.13chr1-1971163419711794197050331970514719711998197121200.080000.000000.00000includedHepG2U2AF2
SECAPZBENSG00000077549.13chr1-1966924519669358196653161966611119670851196709280.094000.000000.00000includedHepG2PTBP1
MXECAPZBENSG00000077549.13chr1-19705033197051471971199819712120196839151968405719746154197462440.121000.003350.042101includedK562DROSHA

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for CAPZB is not avaliable on ENCORE database.