ACO1

General Information

Gene Name : ACO1
Gene ID : ENSG00000122729.18
Essential Gene : No

Functions

RNA stability & decay
Translation regulation

Localization(RBPImage: ACO1)

Nuclei
Nucleoplasm
Mutually Exclusive from Nucleolus
PML bodies
Unknown Nuclear Foci
Cytoplasm
Cytosolic

Domains (AlphaFold: ACO1)

No checked domain (RRM, ZNF, KH, Helicase, Nuclease, dRBM or PUM_HD)

Antibody Validation

MBLI: RN036PW

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	ACO1	ENSG00000122729.18	2.09	2.41	2.25	ENCSR000AEF
HepG2	ACO1	ENSG00000122729.18	22.52	27.04	24.78	ENCSR985KAT
K562	ACO1	ENSG00000122729.18	13.82	15.21	14.52	ENCSR000AEO

Assays

2 Released experiments are available on ENCORE database.

Assay Type	Exp_Name	ENCODE ID	Target label	Biosample	Status	Linked Antibody	Controls	Method	Note
knockdown followed by RNA-seq	ACO1-BGHLV31-HepG2	ENCSR511SYK	ACO1	HepG2	Released		ENCSR538QOG	shRNA	KD% = 58.8,50.3
knockdown followed by RNA-seq	ACO1-BGKcLV11-K562	ENCSR237QLO	ACO1	K562	Released		ENCSR292PXV	CRISPR	KD% = 55.7,64.5

eCLIP

No eCLIP experiment available

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
ACO1	ENCAB923LQZ	RN036PW	1			Released, ENCODE3	BGHLV31-5, Released, ENCODE3	BGKcLV11-3, Released, ENCODE4

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project
ACO1	HepG2	shRNA			BGHLV27-3,BGHLV27-4	BGHLV27-1,BGHLV27-2		NotSatisfied	ENCODE3
ACO1	HepG2	shRNA	ENCSR511SYK	ENCSR538QOG	ACO1_BGHLV31-5,ACO1_BGHLV31-6	NT-BGHLV31-1,NT-BGHLV31-2	58.8,50.3	Released	ENCODE3
ACO1	K562	CRISPR	ENCSR237QLO	ENCSR292PXV	ACO1-BGKcLV11-3,ACO1-BGKcLV11-4	NT-BGKcLV11-1,NT-BGKcLV11-2	55.7,64.5	Released	ENCODE4
ACO1	K562	CRISPR			BGKcLV11-5,BGKcLV11-6	BGKcLV11-1,BGKcLV11-2	36.0,28.4	NotSatisfied	ENCODE4

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

ACO1: Click to RBP Image Database

Nuclei

Nucleoplasm

Mutually Exclusive from Nucleolus

PML bodies

Unknown Nuclear Foci

Cytoplasm

Cytosolic

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
ACO1	Product_ID: RN036PW Lot_ID: 1 Source: MBLI Target Name: ACO1-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for ACO1 is not avaliable on ENCORE database.

Proteins bound to RNA

ACO1 RNA is bound by 4 proteins.

eCLIP assay for ACO1 is not avaliable on ENCORE database.

4 proteins are bound to ACO1 RNA:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr9	32450687	32450749	+	3'-UTR	4.70223	4.66187	HepG2	SUB1
chr9	32384659	32384734	+	5'-UTR,intron-Proximal	3.70024	3.33524	K562	DDX3X
chr9	32408510	32408514	+	5'-UTR,CDS,intron-Proximal	3.90307	11.04556	K562	YBX3
chr9	32408514	32408550	+	5'-UTR,CDS	3.65640	12.44888	K562	YBX3
chr9	32407404	32407427	+	5'-UTR,CDS	3.69307	8.67507	K562	YBX3
chr9	32436260	32436296	+	CDS	3.57688	3.01531	K562	YBX3
chr9	32424553	32424608	+	CDS	4.39189	8.47938	HepG2	BCLAF1
chr9	32429420	32429465	+	CDS	3.02688	4.61799	HepG2	BCLAF1
chr9	32419036	32419077	+	CDS	4.90432	5.23259	HepG2	BCLAF1
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

eCLIP assay for ACO1 is not avaliable on ENCORE database.

Diffrential Expression

7,360 differentially expressed genes after Knockdown/Knockout ACO1 protein.

77 RBPs can affect the levels of ACO1.

7,360 differentially expressed genes after Knockdown/Knockout ACO1 protein :

Only display 100 entries as example. Please click "View All" button to see all 7,360 entries.

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
DPM1	ENSG00000000419.8	1232.44330	1536.03950	-0.31770	2.76570	2.15810	HepG2	ACO1
SCYL3	ENSG00000000457.9	183.68160	119.80610	0.61640	2.93880	2.31470	HepG2	ACO1
C1orf112	ENSG00000000460.12	248.54210	362.03920	-0.54270	4.11410	3.40050	HepG2	ACO1
FUCA2	ENSG00000001036.9	3271.15910	2706.04930	0.27350	4.71400	3.96080	HepG2	ACO1
NFYA	ENSG00000001167.10	1342.88070	981.57080	0.45210	7.40090	6.50430	HepG2	ACO1
STPG1	ENSG00000001460.13	106.33030	64.78390	0.71470	2.34820	1.78070	HepG2	ACO1
SEMA3F	ENSG00000001617.7	394.39220	511.19270	-0.37420	2.91940	2.29740	HepG2	ACO1
CYP51A1	ENSG00000001630.11	2841.46050	5479.84470	-0.94750	53.55730	51.71730	HepG2	ACO1
MYH16	ENSG00000002079.8	468.40790	5.98380	6.29050	123.75100	121.27080	HepG2	ACO1
LAP3	ENSG00000002549.8	2231.96140	1836.84000	0.28100	4.24280	3.52050	HepG2	ACO1
CD99	ENSG00000002586.13	2860.73470	2394.19710	0.25670	3.99090	3.28570	HepG2	ACO1
LASP1	ENSG00000002834.13	11200.41800	7635.39020	0.55270	23.12190	21.75090	HepG2	ACO1
SNX11	ENSG00000002919.10	438.89470	343.50800	0.35340	2.36660	1.79740	HepG2	ACO1
DBNDD1	ENSG00000003249.9	1818.86480	848.76530	1.09950	41.96070	40.27830	HepG2	ACO1
CASP10	ENSG00000003400.10	622.00860	740.88680	-0.25230	1.96130	1.43270	HepG2	ACO1
CFLAR	ENSG00000003402.15	2419.21610	1846.24290	0.38980	7.70520	6.79290	HepG2	ACO1
TFPI	ENSG00000003436.10	13916.71750	10746.43730	0.37290	11.43840	10.38050	HepG2	ACO1
SLC7A2	ENSG00000003989.12	2162.77300	7322.40380	-1.75940	179.74300	176.93340	HepG2	ACO1
ARF5	ENSG00000004059.6	1104.31160	834.06880	0.40480	5.46520	4.66720	HepG2	ACO1
POLDIP2	ENSG00000004142.7	1488.23150	1825.89290	-0.29500	4.18420	3.46520	HepG2	ACO1
PLXND1	ENSG00000004399.8	4856.24830	2860.75180	0.76330	15.91100	14.70750	HepG2	ACO1
AK2	ENSG00000004455.12	2245.59050	3098.64130	-0.46450	11.81410	10.74510	HepG2	ACO1
FKBP4	ENSG00000004478.5	2024.67250	1753.99380	0.20690	2.42590	1.84970	HepG2	ACO1
RBM6	ENSG00000004534.10	3160.09200	3936.89930	-0.31710	4.05160	3.34180	HepG2	ACO1
RECQL	ENSG00000004700.11	1008.67330	747.38220	0.43240	5.77350	4.95810	HepG2	ACO1
ARHGAP33	ENSG00000004777.14	81.11460	329.87460	-2.02390	30.40930	28.91000	HepG2	ACO1
HCCS	ENSG00000004961.10	416.09470	321.18180	0.37340	2.50200	1.91880	HepG2	ACO1
DVL2	ENSG00000004975.7	578.61510	908.59150	-0.65100	10.98250	9.93900	HepG2	ACO1
PRSS22	ENSG00000005001.5	13.16450	2.17750	2.59580	2.06640	1.52630	HepG2	ACO1
UPF1	ENSG00000005007.8	1988.94660	2543.91920	-0.35500	6.70960	5.84700	HepG2	ACO1
SKAP2	ENSG00000005020.8	773.32190	510.68110	0.59850	8.40470	7.46220	HepG2	ACO1
SLC25A5	ENSG00000005022.5	2718.43980	4290.34030	-0.65830	25.23030	23.81340	HepG2	ACO1
POLR2J	ENSG00000005075.11	285.43800	535.72190	-0.90830	13.11140	11.99240	HepG2	ACO1
DHX33	ENSG00000005100.8	825.24930	1275.36060	-0.62800	12.83080	11.72410	HepG2	ACO1
LIG3	ENSG00000005156.7	552.17680	776.88050	-0.49260	6.07540	5.24470	HepG2	ACO1
RPAP3	ENSG00000005175.5	592.23790	469.28360	0.33560	2.68950	2.08950	HepG2	ACO1
ACSM3	ENSG00000005187.7	316.43550	735.84660	-1.21750	17.07120	15.83200	HepG2	ACO1
AC004381.6	ENSG00000005189.15	166.17450	303.17360	-0.86740	7.61500	6.70800	HepG2	ACO1
CIAPIN1	ENSG00000005194.10	1421.29580	987.60290	0.52510	9.93680	8.92960	HepG2	ACO1
FAM214B	ENSG00000005238.15	268.65410	194.88880	0.46300	2.52800	1.94240	HepG2	ACO1
MSL3	ENSG00000005302.13	317.79470	205.22470	0.63080	4.70340	3.95100	HepG2	ACO1
CREBBP	ENSG00000005339.8	1659.85020	1899.82990	-0.19480	2.14450	1.59490	HepG2	ACO1
GCFC2	ENSG00000005436.9	473.43590	600.49160	-0.34300	2.81660	2.20440	HepG2	ACO1
CROT	ENSG00000005469.7	338.73190	230.78290	0.55350	3.98460	3.27980	HepG2	ACO1
ABCB4	ENSG00000005471.11	516.00730	693.01110	-0.42550	4.42740	3.69330	HepG2	ACO1
RHBDD2	ENSG00000005486.12	1064.37870	574.36480	0.88990	20.67460	19.35590	HepG2	ACO1
IBTK	ENSG00000005700.10	2996.70430	2536.47950	0.24040	3.53220	2.86030	HepG2	ACO1
ZNF195	ENSG00000005801.12	657.06070	435.52150	0.59320	7.38730	6.49160	HepG2	ACO1
ITGAL	ENSG00000005844.13	15.99650	115.46830	-2.85170	5.77380	4.95820	HepG2	ACO1
PDK2	ENSG00000005882.7	261.18410	467.61490	-0.84030	10.29940	9.28100	HepG2	ACO1
ITGA3	ENSG00000005884.13	1091.05560	70.73630	3.94700	114.97330	112.56390	HepG2	ACO1
ZFX	ENSG00000005889.11	445.20630	1009.29220	-1.18080	32.68300	31.14720	HepG2	ACO1
LAMP2	ENSG00000005893.11	3115.43700	3860.37560	-0.30930	6.17400	5.33900	HepG2	ACO1
ASB4	ENSG00000005981.8	548.27680	64.76960	3.08140	79.23690	77.15140	HepG2	ACO1
GDE1	ENSG00000006007.7	2234.49380	1662.48050	0.42650	8.74200	7.78530	HepG2	ACO1
CRLF1	ENSG00000006016.6	6113.97460	4984.02520	0.29470	6.45820	5.60900	HepG2	ACO1
OSBPL7	ENSG00000006025.7	133.59070	261.31010	-0.96790	8.04530	7.11820	HepG2	ACO1
TMEM98	ENSG00000006042.7	1353.88710	1620.54580	-0.25940	3.19380	2.54750	HepG2	ACO1
AP2B1	ENSG00000006125.12	5375.08550	4216.49650	0.35010	8.45510	7.50970	HepG2	ACO1
CX3CL1	ENSG00000006210.6	997.32630	2720.21420	-1.44760	85.44810	83.31080	HepG2	ACO1
SPATA20	ENSG00000006282.15	1740.19220	1376.15240	0.33850	5.15850	4.37940	HepG2	ACO1
TNFRSF12A	ENSG00000006327.9	2074.39960	812.16610	1.35270	64.52770	62.57800	HepG2	ACO1
DLX6	ENSG00000006377.9	94.29800	151.87960	-0.68760	2.99040	2.36250	HepG2	ACO1
MAP3K9	ENSG00000006432.11	987.76970	646.73280	0.61090	10.28390	9.26630	HepG2	ACO1
BAIAP2L1	ENSG00000006453.9	1673.66960	730.47130	1.19600	46.06530	44.34260	HepG2	ACO1
GGCT	ENSG00000006625.13	372.96300	485.03750	-0.37910	2.83330	2.21920	HepG2	ACO1
DBF4	ENSG00000006634.3	305.23260	501.80610	-0.71720	3.80240	3.11090	HepG2	ACO1
IFRD1	ENSG00000006652.9	1100.51040	695.71440	0.66150	12.70990	11.60780	HepG2	ACO1
PAF1	ENSG00000006712.10	1077.81970	890.54630	0.27530	2.81790	2.20560	HepG2	ACO1
VPS41	ENSG00000006715.11	638.03140	841.02180	-0.39850	4.50340	3.76400	HepG2	ACO1
ARHGAP44	ENSG00000006740.12	75.26870	114.89400	-0.61020	2.00190	1.46940	HepG2	ACO1
ELAC2	ENSG00000006744.14	1031.72350	803.01010	0.36150	4.33280	3.60460	HepG2	ACO1
ARSD	ENSG00000006756.11	624.89320	297.77550	1.06930	18.96770	17.68250	HepG2	ACO1
ADIPOR2	ENSG00000006831.9	2710.57670	3415.70730	-0.33360	5.42820	4.63260	HepG2	ACO1
MARK4	ENSG00000007047.10	700.85890	924.80870	-0.40000	4.81280	4.05260	HepG2	ACO1
CCDC124	ENSG00000007080.6	467.63940	367.48570	0.34760	2.42600	1.84970	HepG2	ACO1
PAFAH1B1	ENSG00000007168.8	3279.80860	2122.46580	0.62780	20.71510	19.39570	HepG2	ACO1
KIAA0100	ENSG00000007202.10	4977.38410	3922.14940	0.34360	8.00240	7.07740	HepG2	ACO1
TRAPPC6A	ENSG00000007255.6	53.44530	119.24330	-1.15780	5.41710	4.62210	HepG2	ACO1
PAX6	ENSG00000007372.16	51.46900	16.34240	1.65500	4.17270	3.45470	HepG2	ACO1
RHBDF1	ENSG00000007384.11	742.12790	322.76230	1.20110	26.24560	24.81480	HepG2	ACO1
TEAD3	ENSG00000007866.14	829.84940	1092.09850	-0.39620	5.23850	4.45440	HepG2	ACO1
E2F2	ENSG00000007968.6	141.85960	247.70230	-0.80410	5.73250	4.91910	HepG2	ACO1
CDK11A	ENSG00000008128.18	921.49310	689.67660	0.41800	5.13410	4.35580	HepG2	ACO1
CYTH3	ENSG00000008256.11	378.65330	172.03970	1.13800	13.98000	12.83740	HepG2	ACO1
ADAM22	ENSG00000008277.10	211.60840	294.98390	-0.47920	2.04040	1.50340	HepG2	ACO1
PLEKHG6	ENSG00000008323.11	90.12570	353.30660	-1.97090	31.06600	29.55450	HepG2	ACO1
MPND	ENSG00000008382.11	126.67360	255.93470	-1.01470	2.72590	2.12240	HepG2	ACO1
CRY1	ENSG00000008405.7	547.59560	451.21560	0.27920	1.91890	1.39540	HepG2	ACO1
ST3GAL1	ENSG00000008513.10	854.36080	1213.42810	-0.50620	8.54490	7.59650	HepG2	ACO1
IL32	ENSG00000008517.12	3141.79110	2455.63220	0.35540	4.59870	3.85240	HepG2	ACO1
PKD1	ENSG00000008710.13	1768.32720	1521.44270	0.21680	2.46350	1.88420	HepG2	ACO1
MAPK8IP2	ENSG00000008735.10	65.17490	106.71860	-0.71140	2.36450	1.79550	HepG2	ACO1
MED24	ENSG00000008838.13	2596.08990	2145.22670	0.27510	4.31600	3.58920	HepG2	ACO1
RHOBTB2	ENSG00000008853.12	199.73480	324.45090	-0.69990	5.70750	4.89570	HepG2	ACO1
HEATR5B	ENSG00000008869.7	1103.83430	663.62100	0.73400	15.21820	14.03570	HepG2	ACO1
SEC62	ENSG00000008952.12	3505.31730	2871.70960	0.28750	4.41900	3.68580	HepG2	ACO1
RPS20	ENSG00000008988.5	3422.16960	6755.35620	-0.98110	60.81540	58.89390	HepG2	ACO1
UBE3C	ENSG00000009335.13	1770.98890	1326.49980	0.41680	7.47500	6.57540	HepG2	ACO1
REV3L	ENSG00000009413.11	2118.15690	1332.49490	0.66860	19.00860	17.72210	HepG2	ACO1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

77 RBPs can affect the gene expression of ACO1 :

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
ACO1	ENSG00000122729.14	503.10040	1109.48120	-1.14100	32.97370	31.43340	HepG2	ACO1
ACO1	ENSG00000122729.14	600.76870	939.46040	-0.64500	6.35140	4.92200	HepG2	ADAR
ACO1	ENSG00000122729.14	1179.77860	1674.46470	-0.50520	3.84670	3.23450	HepG2	AKAP1
ACO1	ENSG00000122729.14	968.60100	1385.44520	-0.51640	4.52370	3.53140	HepG2	ASCC1
ACO1	ENSG00000122729.14	739.35010	1177.49070	-0.67140	6.24380	4.81020	HepG2	BCCIP
ACO1	ENSG00000122729.14	1137.37150	1576.04780	-0.47060	3.07300	2.04260	HepG2	CCAR1
ACO1	ENSG00000122729.14	772.70060	1040.01150	-0.42860	3.94410	2.63310	HepG2	CPSF7
ACO1	ENSG00000122729.14	1081.64010	1421.83240	-0.39450	5.19000	4.35950	HepG2	CELF1
ACO1	ENSG00000122729.14	1196.94950	1528.91000	-0.35310	5.70880	4.69840	HepG2	DAZAP1
ACO1	ENSG00000122729.14	1341.02870	1013.16310	0.40440	3.58530	2.82110	HepG2	DDX21
ACO1	ENSG00000122729.14	1173.51620	1603.93810	-0.45080	3.59590	2.89360	HepG2	DDX3X
ACO1	ENSG00000122729.14	726.74480	1157.76360	-0.67180	6.31380	5.20250	HepG2	DDX55
ACO1	ENSG00000122729.14	886.92620	1377.98660	-0.63570	5.53090	4.68400	HepG2	DDX6
ACO1	ENSG00000122729.14	1278.27390	1061.45030	0.26810	2.64840	1.98420	HepG2	DKC1
ACO1	ENSG00000122729.14	708.76010	946.02790	-0.41660	4.41560	3.54250	HepG2	DNAJC21
ACO1	ENSG00000122729.14	722.35520	937.59010	-0.37620	2.61350	1.97650	HepG2	DNAJC2
ACO1	ENSG00000122729.14	804.56170	1324.52260	-0.71920	7.73980	6.78420	HepG2	EIF2S1
ACO1	ENSG00000122729.14	582.23720	747.91040	-0.36130	2.15380	1.34750	HepG2	EIF3D
ACO1	ENSG00000122729.14	1199.69220	1508.28510	-0.33020	4.10990	3.12770	HepG2	EIF4G1
ACO1	ENSG00000122729.14	1381.99030	1743.13080	-0.33490	4.44610	3.71690	HepG2	ETF1
ACO1	ENSG00000122729.14	962.37150	1275.37470	-0.40630	2.55090	1.80850	HepG2	FIP1L1
ACO1	ENSG00000122729.14	643.76630	1233.94280	-0.93870	8.84230	6.97320	HepG2	FUS
ACO1	ENSG00000122729.14	1013.78660	1477.03080	-0.54290	5.08760	4.16970	HepG2	FXR1
ACO1	ENSG00000122729.14	1009.43110	1370.03230	-0.44070	3.22900	2.51300	HepG2	G3BP1
ACO1	ENSG00000122729.14	732.31170	1059.18400	-0.53240	8.24620	6.67030	HepG2	HDGF
ACO1	ENSG00000122729.14	689.37870	955.09020	-0.47030	4.15080	3.38210	HepG2	HNRNPA1
ACO1	ENSG00000122729.14	1093.97640	1405.06810	-0.36110	4.61830	3.46230	HepG2	HNRNPA2B1
ACO1	ENSG00000122729.14	765.99570	1392.74770	-0.86250	25.38960	23.56630	HepG2	HNRNPL
ACO1	ENSG00000122729.14	837.97150	1055.31190	-0.33270	3.60330	2.92010	HepG2	HNRNPU
ACO1	ENSG00000122729.14	856.94040	1077.97090	-0.33110	4.57560	3.65230	HepG2	ILF2
ACO1	ENSG00000122729.14	833.48170	1014.15070	-0.28300	3.06270	1.99250	HepG2	KIF1C
ACO1	ENSG00000122729.14	1230.99940	1520.74250	-0.30490	1.82370	1.30280	HepG2	NCBP2
ACO1	ENSG00000122729.14	946.20890	1516.05920	-0.68010	8.61310	7.29350	HepG2	NOL12
ACO1	ENSG00000122729.14	1532.87080	999.96610	0.61620	7.02130	5.86550	HepG2	NSUN2
ACO1	ENSG00000122729.14	669.05110	1044.61300	-0.64280	10.61820	9.13690	HepG2	PARN
ACO1	ENSG00000122729.14	758.16000	941.25880	-0.31210	2.74470	2.01000	HepG2	PPIL4
ACO1	ENSG00000122729.14	691.70810	892.87680	-0.36830	2.43410	1.67440	HepG2	PRPF8
ACO1	ENSG00000122729.14	1017.40460	1536.22200	-0.59450	14.88200	13.73340	HepG2	PUM1
ACO1	ENSG00000122729.14	1107.00290	1535.11830	-0.47170	6.03030	5.05270	HepG2	PUM2
ACO1	ENSG00000122729.14	1442.54710	1130.06580	0.35210	4.98330	4.20050	HepG2	PUS1
ACO1	ENSG00000122729.14	956.50030	1540.45340	-0.68750	11.88420	10.72300	HepG2	QKI
ACO1	ENSG00000122729.14	1010.21450	1412.34240	-0.48340	5.78940	4.60660	HepG2	RBM15
ACO1	ENSG00000122729.14	1177.53840	1456.93830	-0.30720	3.06640	2.52880	HepG2	RBM22
ACO1	ENSG00000122729.14	790.86870	1077.01620	-0.44550	3.37390	2.27290	HepG2	RBM27
ACO1	ENSG00000122729.14	583.91090	727.80360	-0.31780	2.04530	1.50990	HepG2	RPS19
ACO1	ENSG00000122729.14	775.49230	1013.93710	-0.38680	2.59570	1.55700	HepG2	RPS5
ACO1	ENSG00000122729.14	569.44010	883.21600	-0.63320	5.28780	4.23370	HepG2	RRP9
ACO1	ENSG00000122729.14	707.51280	939.81840	-0.40960	5.08000	4.25480	HepG2	SAFB2
ACO1	ENSG00000122729.14	1444.90390	1116.28300	0.37220	2.83730	2.12230	HepG2	SF3B1
ACO1	ENSG00000122729.14	1192.41880	1480.87020	-0.31260	3.61650	2.95350	HepG2	SF3B4
ACO1	ENSG00000122729.14	745.14990	1096.01480	-0.55670	10.17990	9.07180	HepG2	SMN1
ACO1	ENSG00000122729.14	750.35690	1148.94500	-0.61470	4.42200	3.19270	HepG2	SMNDC1
ACO1	ENSG00000122729.14	1158.33440	1645.56450	-0.50650	9.77300	8.98820	HepG2	SRFBP1
ACO1	ENSG00000122729.14	791.63650	1201.08510	-0.60140	4.49600	3.19080	HepG2	SRSF3
ACO1	ENSG00000122729.14	1069.93900	1428.84960	-0.41730	6.20840	5.32430	HepG2	SRSF5
ACO1	ENSG00000122729.14	883.34710	1257.55170	-0.50960	8.40560	7.53580	HepG2	SRSF9
ACO1	ENSG00000122729.14	2506.21170	1428.75040	0.81070	27.68490	26.44140	HepG2	SSB
ACO1	ENSG00000122729.14	695.31900	1053.54500	-0.59950	3.53370	2.16030	HepG2	SUB1
ACO1	ENSG00000122729.14	1392.32660	1625.02610	-0.22300	2.63880	2.02790	HepG2	SUCLG1
ACO1	ENSG00000122729.14	830.48580	1152.46500	-0.47270	3.59290	2.83750	HepG2	SUPV3L1
ACO1	ENSG00000122729.14	1142.26910	1389.42150	-0.28260	2.66690	2.11550	HepG2	TAF15
ACO1	ENSG00000122729.14	576.16960	772.41370	-0.42290	2.88340	1.86810	HepG2	TFIP11
ACO1	ENSG00000122729.14	990.34580	1276.62570	-0.36630	3.49610	2.56040	HepG2	TIA1
ACO1	ENSG00000122729.14	820.51820	1034.59260	-0.33450	3.22970	2.63090	HepG2	TRIM56
ACO1	ENSG00000122729.14	899.53710	1413.79080	-0.65230	9.32170	7.53930	HepG2	TUFM
ACO1	ENSG00000122729.14	1051.60520	1496.44340	-0.50890	3.98920	2.97340	HepG2	UBE2L3
ACO1	ENSG00000122729.14	311.54320	680.74810	-1.12770	14.26410	12.57290	HepG2	UCHL5
ACO1	ENSG00000122729.14	686.88840	1005.38570	-0.54960	8.98130	7.88850	HepG2	ZC3H8
ACO1	ENSG00000122729.14	1013.28090	1361.67700	-0.42640	5.51930	4.22890	K562	DKC1
ACO1	ENSG00000122729.14	581.93310	797.53690	-0.45470	2.70130	1.43900	K562	EEF2
ACO1	ENSG00000122729.14	813.70370	995.33230	-0.29070	2.67600	1.49320	K562	EIF2S1
ACO1	ENSG00000122729.14	744.17390	1040.72340	-0.48390	6.02940	5.02890	K562	EIF2S2
ACO1	ENSG00000122729.14	690.18450	946.72170	-0.45600	3.90380	2.93320	K562	EIF4A3
ACO1	ENSG00000122729.14	1492.28120	1857.75260	-0.31600	3.45990	2.41290	K562	EIF4G2
ACO1	ENSG00000122729.14	621.31350	984.54910	-0.66410	10.02790	8.96070	K562	FXR1
ACO1	ENSG00000122729.14	855.01090	1127.78930	-0.39950	3.75450	2.50280	K562	HNRNPA1
ACO1	ENSG00000122729.14	596.89020	761.02300	-0.35050	2.37840	1.81900	K562	HNRNPC
ACO1	ENSG00000122729.14	1112.43790	1435.32760	-0.36770	2.90790	2.09350	K562	HSPD1
ACO1	ENSG00000122729.14	1576.44140	2026.97080	-0.36270	3.29060	2.40150	K562	PUF60
ACO1	ENSG00000122729.14	1563.41690	1254.94700	0.31700	2.38060	1.86830	K562	PUS1
ACO1	ENSG00000122729.14	821.46470	1068.70250	-0.37960	2.98680	2.11020	K562	RBM22
ACO1	ENSG00000122729.14	990.16870	763.67060	0.37460	2.15740	1.44090	K562	RPS19
ACO1	ENSG00000122729.14	534.96820	1092.95180	-1.03070	18.43200	16.63210	K562	SRSF1
ACO1	ENSG00000122729.14	709.35090	1106.01610	-0.64080	6.77230	5.62360	K562	TARDBP
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for ACO1 is not available on ENCORE database.

3 RBPs can affect the splicing of ACO1 :

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	ACO1	ENSG00000122729.14	chr9	+	32386368	32386436	32384617	32384733	32405482	32405601	-0.14900	0.00004	0.01822	excluded	HepG2	BCLAF1
SE	ACO1	ENSG00000122729.14	chr9	+	32386368	32386436	32384617	32384733	32405482	32405601	0.19300	0.00049	0.01414	included	HepG2	SRSF1
SE	ACO1	ENSG00000122729.14	chr9	+	32386368	32386436	32384617	32384733	32405482	32405601	-0.14900	0.00004	0.01443	excluded	HepG2	DDX55

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

ACO1

General Information

Functions

Localization(RBPImage: ACO1)

Domains (AlphaFold: ACO1)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for ACO1 is not avaliable on ENCORE database.

4 proteins are bound to ACO1 RNA:

eCLIP assay for ACO1 is not avaliable on ENCORE database.

Diffrential Expression

7,360 differentially expressed genes after Knockdown/Knockout ACO1 protein :

77 RBPs can affect the gene expression of ACO1 :

The Knockdown/knockout RNA-Seq assay for ACO1 is not available on ENCORE database.

3 RBPs can affect the splicing of ACO1 :

The Knockdown/knockout RNA-Seq assay for ACO1 is not avaliable on ENCORE database.