RBM6

General Information

Gene Name : RBM6
Gene ID : ENSG00000004534.14
Essential Gene : No

Functions

Splicing regulation

Localization(RBPImage: RBM6)

Nuclei
Nucleoplasm
Mutually Exclusive from Nucleolus
Speckles
Cytoplasm
Cytosolic

Domains (AlphaFold: RBM6)

RRM

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	RBM6	ENSG00000004534.14	86.09	69.29	77.69	ENCSR000AEF
HepG2	RBM6	ENSG00000004534.14	56.04	77.47	66.75	ENCSR985KAT
K562	RBM6	ENSG00000004534.14	47.88	55.28	51.58	ENCSR000AEO

Assays

1 Released experiments are available on ENCORE database.

Assay Type	Exp_Name	ENCODE ID	Target label	Biosample	Status	Linked Antibody	Controls	Method	Note
RNA Bind-n-Seq	RBNS: RBM6	ENCSR548RVM	RBM6	cell-free sample	Released		ENCSR721PRM

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

GeneName	gene_aliases	Status	Project	Note
RBM6	RBM6		Released	ENCODE3

Localization Image in HepG2

RBM6: Click to RBP Image Database

Nuclei

Nucleoplasm

Mutually Exclusive from Nucleolus

Speckles

Cytoplasm

Cytosolic

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for RBM6 is not avaliable on ENCORE database.

The binding motifs of RBM6

Proteins bound to RNA

RBM6 RNA is bound by 52 proteins.

CanvasJS.com

eCLIP assay for RBM6 is not avaliable on ENCORE database.

52 proteins are bound to RBM6 RNA:

Show entries

Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr3	50072466	50072560	+	intron-Distal	5.99249	46.98271	HepG2	PCBP2
chr3	50000087	50000154	+	5'-UTR,CDS,intron-Proximal	4.75870	34.31957	HepG2	PRPF8
chr3	50102499	50102559	+	3'-UTR,CDS	5.50433	32.83739	K562	UCHL5
chr3	50099116	50099177	+	3'-UTR,intron-Distal	3.28803	32.77801	HepG2	BCLAF1
chr3	50102470	50102559	+	3'-UTR,CDS	4.38660	32.31586	HepG2	BCLAF1
chr3	50102473	50102561	+	3'-UTR,CDS,intron-Proximal	3.04536	31.09869	HepG2	PPIG
chr3	50102522	50102541	+	3'-UTR,CDS	5.11126	30.60941	HepG2	GRWD1
chr3	50102473	50102520	+	3'-UTR,CDS	4.84844	30.03175	HepG2	GRWD1
chr3	50053474	50053577	+	intron-Distal	5.19619	27.00536	HepG2	QKI
chr3	50137414	50137492	+	3'-UTR,5'-UTR,CDS,intron-Proximal	3.91224	25.39487	HepG2	PPIG
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 290 entries

eCLIP assay for RBM6 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for RBM6 is not available on ENCORE database.
108 RBPs can affect the levels of RBM6.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for RBM6 is not available on ENCORE database.

108 RBPs can affect the gene expression of RBM6 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
RBM6	ENSG00000004534.10	2737.00800	4757.74860	-0.79770	43.02860	40.77820	HepG2	HNRNPL
RBM6	ENSG00000004534.10	5694.96560	2785.86980	1.03150	31.16400	29.54730	HepG2	TAF15
RBM6	ENSG00000004534.10	4686.76920	2226.14140	1.07390	29.19110	26.79480	HepG2	FUBP3
RBM6	ENSG00000004534.10	3444.26200	5248.58200	-0.60770	27.63300	26.14820	HepG2	PUM1
RBM6	ENSG00000004534.10	9121.90410	4526.26800	1.01090	24.84700	23.60500	HepG2	RBM22
RBM6	ENSG00000004534.10	5092.86640	3087.97760	0.72170	16.46760	15.12780	HepG2	QKI
RBM6	ENSG00000004534.10	1205.20040	2063.03020	-0.77550	14.47000	12.84890	K562	SRSF1
RBM6	ENSG00000004534.10	1727.58150	2840.27720	-0.71730	14.27540	12.46700	K562	CPSF6
RBM6	ENSG00000004534.10	4087.95280	5551.82050	-0.44160	12.98820	11.80620	HepG2	SUCLG1
RBM6	ENSG00000004534.10	1884.79330	3038.63470	-0.68900	11.34810	10.02350	HepG2	HNRNPC
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 126 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for RBM6 is not available on ENCORE database.

47 RBPs can affect the splicing of RBM6 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	FDR	is_included	Cell Line	Affected by RBP
SE	RBM6	ENSG00000004534.10	chr3	+	50036872	50036946	50012755	50012825	50085677	50085752	-0.33500	0.00124	excluded	HepG2	PRPF8
SE	RBM6	ENSG00000004534.10	chr3	+	50099046	50099181	50098894	50098980	50099394	50099541	-0.09100	0.00000	excluded	HepG2	HNRNPK
SE	RBM6	ENSG00000004534.10	chr3	+	50099046	50099181	50098894	50098980	50099394	50099541	-0.08400	0.00041	excluded	HepG2	AKAP1
SE	RBM6	ENSG00000004534.10	chr3	+	50036872	50036946	50012755	50012825	50085677	50085752	0.40300	0.00000	included	K562	FXR1
SE	RBM6	ENSG00000004534.10	chr3	+	50036872	50036946	50012755	50012825	50085677	50085752	-0.32300	0.00003	excluded	K562	PUS1
SE	RBM6	ENSG00000004534.10	chr3	+	50036872	50036946	50012755	50012825	50085677	50085752	-0.33200	0.00024	excluded	K562	SF3B1
SE	RBM6	ENSG00000004534.10	chr3	+	50036872	50036946	50012755	50012825	50085677	50085752	0.34400	0.00024	included	K562	PTBP1
SE	RBM6	ENSG00000004534.10	chr3	+	50004902	50006181	50000008	50000118	50009491	50009581	-0.23900	0.00006	excluded	K562	HNRNPC
A3SS	RBM6	ENSG00000004534.10	chr3	+	50004630	50006181	50004902	50006181	50000008	50000118	0.24200	0.00000	longer	HepG2	U2AF2
A3SS	RBM6	ENSG00000004534.10	chr3	+	50099367	50099541	50099394	50099541	50098894	50098980	0.06700	0.00000	longer	K562	AQR

Showing 1 to 10 of 124 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

RBM6

General Information

Functions

Localization(RBPImage: RBM6)

Domains (AlphaFold: RBM6)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for RBM6 is not avaliable on ENCORE database.

52 proteins are bound to RBM6 RNA:

eCLIP assay for RBM6 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for RBM6 is not available on ENCORE database.

108 RBPs can affect the gene expression of RBM6 :

The Knockdown/knockout RNA-Seq assay for RBM6 is not available on ENCORE database.

47 RBPs can affect the splicing of RBM6 :

The Knockdown/knockout RNA-Seq assay for RBM6 is not avaliable on ENCORE database.