HLTF

General Information

Gene Name       : HLTF
Gene ID             : ENSG00000071794.15
Essential Gene : No

Functions

Localization(RBPImage: HLTF)

Domains (AlphaFold: HLTF)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878HLTFENSG00000071794.1522.6120.6921.65ENCSR000AEF
HepG2HLTFENSG00000071794.156.6814.3210.50ENCSR985KAT
K562HLTFENSG00000071794.1531.0833.8832.48ENCSR000AEO

Assays

4 Released experiments are available on ENCORE database.

Assay TypeExp_NameENCODE IDTarget labelBiosampleStatusLinked AntibodyControlsMethodNote
eCLIPeCLIP: 522ENCSR589YHMHLTFK562ReleasedENCAB902OZZENCSR502NKG  
eCLIPeCLIP: 651ENCSR647HOXHLTFHepG2ReleasedENCAB902OZZENCSR705DCQ  
knockdown followed by RNA-seq HLTF-BGKLV13-K562ENCSR958NDUHLTFK562ReleasedENCSR815CVQ   shRNAKD% = 84.5,84.6
knockdown followed by RNA-seq HLTF-BGHLV14-HepG2ENCSR010ZMZHLTFHepG2ReleasedENCSR491FOC   shRNAKD% = 91.8,92.9






  eCLIP  
  RBP    Exp_UID    Cell_Line    ENCODE_ACCESSION    Control_ENCODE_ACCESSION    ENCODE_Antibody_ID    Antibody    Lot_num    Status    Project  
HLTF522K562ENCSR589YHMENCSR502NKGENCAB902OZZA300-230A1ReleasedENCODE3
HLTF651HepG2ENCSR647HOXENCSR705DCQENCAB902OZZA300-230A2ReleasedENCODE4


  Antibody Validation  
  GeneName    Antibody_DCC_ID    Product_ID    Lot_ID    Phosphate    HepG2 Primary Validation    K562 Primary Validation    HepG2 Secondary Validation    K562 Secondary Validation  
HLTFENCAB902OZZA300-230A2Released, ENCODE3Released, ENCODE3BGHLV14-25, Released, ENCODE3BGKLV13-3, Released, ENCODE3


  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
HLTFK562shRNAENCSR958NDUENCSR815CVQHLTF_BGKLV13_3,HLTF_BGKLV13_4NT_BGKLV13_1,NT_BGKLV13_284.5,84.6ReleasedENCODE3
HLTFK562shRNABGKLV40-5,BGKLV40-6BGKLV40-1,BGKLV40-280.1,75.2OthersENCODE4
HLTFHepG2shRNAENCSR010ZMZENCSR491FOCHLTF_BGHLV14-25,HLTF_BGHLV14-26NT_BGHLV14-1,NT_BGHLV14-291.8,92.9ReleasedENCODE3
HLTFHepG2shRNABGHLV39-5,BGHLV39-6BGHLV39-1,BGHLV39-244.0,56.0OthersENCODE4


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  
    HLTF: Click to RBP Image Database
  • Nuclei
  • Nucleoplasm
  • Mutually Exclusive from Nucleolus
  • Speckles
  • Cytoplasm
  • Compartment/Organelle
  • Golgi
  • Nuclear release mitosis












    • RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela
    HLTFProduct_ID: A300-230A
    Lot_ID: 2
    Source: Bethyl Labs
    Target Name: HLTF-human    		 HepG2_Bethyl_A300-230A_2_HLTF.png<br>Caption: IP-Western Blot analysis of HepG2 whole cell lysate using HLTF specific antibody. Lane 1 is 1% of twenty million whole cell lysate input and lane 2 is 25% of IP enrichment using rabbit normal IgG (lanes under 'IgG'). Lane 3 is 1% of twenty million whole cell lysate input and lane 4 is 10% IP enrichment using rabbit polyclonal anti-HLTF antibody (lanes under 'HLTF').
    		 HLTF_Secondary_Western.png<br>Caption: Western blot following shRNA against HLTF in K562 and HepG2 whole cell lysate using HLTF specific antibody. Lane 1 is a ladder, lane 2 is K562 non-targeting control knockdown, lane 3 and 4 are two different shRNAs against HLTF. Lanes 5-7 follow the same pattern, but in HepG2. HLTF protein appears as the green band, Tubulin serves as a control and appears in red.
    		 K562_Bethyl_A300-230A_2_HLTF.png<br>Caption: IP-Western Blot analysis of K562 whole cell lysate using HLTF specific antibody. Lane 1 is 1% of twenty million whole cell lysate input and lane 2 is 25% of IP enrichment using rabbit normal IgG (lanes under 'IgG'). Lane 3 is 1% of twenty million whole cell lysate input and lane 4 is 10% IP enrichment using rabbit polyclonal anti-HLTF antibody (lanes under 'HLTF').
    		 HLTF_Secondary_Western.png<br>Caption: Western blot following shRNA against HLTF in K562 and HepG2 whole cell lysate using HLTF specific antibody. Lane 1 is a ladder, lane 2 is K562 non-targeting control knockdown, lane 3 and 4 are two different shRNAs against HLTF. Lanes 5-7 follow the same pattern, but in HepG2. HLTF protein appears as the green band, Tubulin serves as a control and appears in red.








    RNA Targets
    • HLTF protein binds to 3,535 RNA regions.  





    Proteins bound to RNA
    • HLTF RNA is bound by 24 proteins.  






    HLTF protein has 3,535 RNA targets:

    Only display 100 entries as example. Please click "View All" button to see all 3,535 entries.     

    RBP Chr Start End Strand log2(fold change) -log(p-value) Cell Line Matched Gene Matched Area
    HLTFchr79172620591726287+5.117797.09496HepG2AKAP9CDS
    HLTFchr101959156419591632+3.343573.34034HepG2C10orf112intron-Distal
    HLTFchr135260454152604629+3.645013.88253HepG2UTP14CCDS
    HLTFchr79963306699633110+5.0930914.95272HepG2ZKSCAN13'-UTR
    HLTFchr6167395031167395091-3.181354.90436HepG2RP1-167A14.2intron-Distal
    HLTFchr182114650921146549-4.009035.63010HepG2NPC1intron-Distal
    HLTFchr9136683615136683687-4.536295.01506HepG2VAV2intron-Distal
    HLTFchr7149304193149304271-4.316003.55983HepG2ZNF767intron-Distal
    HLTFchr57050392670503957-3.704807.66103HepG2GUSBP9intron-Distal
    HLTFchr2034856893485743+3.682613.34920HepG2ATRNintron-Distal
    HLTFchr6145137549145137575+3.179783.07152HepG2UTRNintron-Distal
    HLTFchr8610061610111-3.115734.29582HepG2ERICH1intron-Distal
    HLTFchr2188397417188397470+3.1471727.51144HepG2AC007319.1intron-Distal
    HLTFchr172749313627493188-3.734255.26073HepG2MYO18ACDS,intron-Distal
    HLTFchr172700334327003407+3.591286.52093HepG2SUPT6HCDS
    HLTFchr7158348065158348116-3.039735.55322HepG2PTPRN2intron-Distal
    HLTFchr1153824236153824287-4.156793.24150HepG2GATAD2Bintron-Distal
    HLTFchr109791772497917784+3.9846413.39861HepG2ZNF518Aintron-Distal
    HLTFchr64791464247914710-3.065045.82118HepG2PTCHD4intron-Distal
    HLTFchr2188355668188355725-3.247254.35275HepG2TFPIintron-Distal
    HLTFchr135228129252281353+3.762545.26073HepG2WDFY2intron-Distal
    HLTFchrX133061968133062013-3.9440022.98970HepG2GPC3intron-Distal
    HLTFchr124635788846357961-3.574853.28742K562SCAF113'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal
    HLTFchr9115410540115410586+3.532833.34920HepG2KIAA1958intron-Distal
    HLTFchr81304456013044650-3.1888411.08719HepG2DLC1intron-Distal
    HLTFchr135128981251289861+3.928535.84561HepG2DLEU1intron-Distal
    HLTFchr77886528278865405-3.332213.08145HepG2MAGI2intron-Distal
    HLTFchr161056269010562814+3.0192910.63391HepG2ATF7IP2intron-Distal
    HLTFchr1723234352323506-3.089503.07152HepG2METTL163'-UTR,CDS,intron-Distal,intron-Proximal
    HLTFchr6144922431144922471+3.197776.87621HepG2UTRNintron-Distal
    HLTFchr24469500644695090+3.260013.08145HepG2CAMKMTintron-Distal
    HLTFchr214057119940571312-3.574853.25559K562BRWD13'-UTR,CDS,intron-Distal,intron-Proximal
    HLTFchr111019100210191072-4.171253.55983HepG2SBF2intron-Distal
    HLTFchr1203769146203769242+3.8288415.45324HepG2ZC3H11A, ZBED65'-UTR,CDS,intron-Distal
    HLTFchr176653719266537235+3.267573.34920HepG2PRKAR1Aintron-Distal
    HLTFchr1229427446229427515+4.171253.53509HepG2RAB4Aintron-Distal
    HLTFchr193994406839944154+3.181354.84290HepG2SUPT5HCDS
    HLTFchr57393159773931675-3.213556.17236HepG2ENC1CDS,intron-Distal
    HLTFchr11129706352129706403+3.061655.81619HepG2TMEM45Bintron-Distal
    HLTFchr26315719763157299+4.0975315.37866HepG2EHBP1intron-Distal
    HLTFchr63052631330526346+4.086283.53509HepG2PRR3intron-Distal
    HLTFchr2081545368154589+3.651298.03004HepG2PLCB1intron-Distal
    HLTFchr2170493983170494033+3.014093.80877HepG2PPIG3'-UTR,CDS
    HLTFchr161050991610509957+3.608484.70379HepG2ATF7IP2intron-Distal
    HLTFchr176585010765850165+3.979668.81167HepG2BPTFCDS
    HLTFchr91476691014766952-4.878766.81402HepG2FREM1intron-Distal
    HLTFchr161971841719718481-3.772564.74894HepG2KNOP1CDS,intron-Distal,intron-Proximal
    HLTFchr106100210161002202+4.0146113.39303HepG2PHYHIPLintron-Distal
    HLTFchr221614993916150049-4.200696.22361HepG2AP000525.9intron-Distal
    HLTFchr8124414629124414727-4.397833.82973HepG2ATAD2intron-Distal
    HLTFchr1203767517203767551+3.887308.01794HepG2ZBED6, ZC3H11ACDS,intron-Distal
    HLTFchr6145135342145135445+3.3933411.11951HepG2UTRNintron-Distal
    HLTFchr8121679828121679916-3.373029.23968HepG2SNTB1intron-Distal
    HLTFchr2034850213485074+3.419574.07970HepG2ATRNintron-Distal
    HLTFchr39956789799567979-3.4064312.49519HepG2FILIP1LCDS,intron-Distal
    HLTFchr174503822245038275+3.746107.94789HepG2GOSR2, RP11-156P1.2intron-Distal
    HLTFchr1613686921368756+3.367698.30927HepG2UBE2Iintron-Distal
    HLTFchr83864487438644915+3.989963.53509HepG2TACC15'-UTR,intron-Distal
    HLTFchr211634029616340362-3.1917111.09290HepG2NRIP1CDS,intron-Distal,intron-Proximal
    HLTFchr8121654941121654989-3.177584.56843HepG2SNTB1intron-Distal
    HLTFchr176642210966422169+3.307765.82118HepG2RP11-120M18.2intron-Distal
    HLTFchr26163284461632905-3.5262510.16125HepG2USP34CDS,intron-Distal
    HLTFchr202046673520466766-3.447815.86900HepG2RALGAPA2intron-Distal
    HLTFchr10123845144123845230+3.350303.61820HepG2TACC2CDS,intron-Distal
    HLTFchr27466927074669288-3.089503.07152HepG2RTKNintron-Distal
    HLTFchr289312608931307-4.228983.26547HepG2KIDINS2205'-UTR,CDS,intron-Distal
    HLTFchr7157534350157534397-3.986273.26547HepG2PTPRN2intron-Distal
    HLTFchr27165080671650875+4.7319511.55336HepG2ZNF638CDS,intron-Distal
    HLTFchr172078776020787797+3.841315.26073HepG2RP11-344E13.3intron-Distal
    HLTFchr81303197413032029-3.176245.86900HepG2DLC1intron-Distal
    HLTFchr1155450131155450192-3.407067.26312HepG2ASH1LCDS,intron-Distal
    HLTFchr122680463526804677-3.129899.45872HepG2ITPR2intron-Distal
    HLTFchr109791967897919732+3.1103711.78867HepG2ZNF518Aintron-Distal
    HLTFchr6170694605170694677+4.002139.44974HepG2FAM120Bintron-Distal
    HLTFchrX106310391106310466-4.665505.31233HepG2RBM413'-UTR,intron-Distal
    HLTFchr195732656157326613-3.0526241.48645HepG2ZIM2, PEG3CDS,intron-Distal
    HLTFchr1628136762813727+3.2725616.07734HepG2SRRM2CDS
    HLTFchr2238488795238488852-3.1032210.61869HepG2RAB17intron-Distal
    HLTFchr211633721116337229-4.032836.43511HepG2NRIP1CDS,intron-Distal
    HLTFchr106497450464974571-3.285749.90091HepG2JMJD1CCDS,intron-Distal
    HLTFchr36067255360672645-3.221013.07152HepG2FHITintron-Distal
    HLTFchr633030703303135-4.1655011.12688HepG2SLC22A23intron-Distal
    HLTFchr7157668720157668810-3.955209.96828HepG2PTPRN2intron-Distal
    HLTFchr111733249517332558+3.599054.15543HepG2NUCB2CDS,intron-Proximal
    HLTFchr74374111243741179-4.247253.53509HepG2COA1intron-Distal
    HLTFchr21145759911457653-4.226344.15056HepG2ROCK2intron-Distal
    HLTFchr8100147823100147896+3.721014.16915HepG2VPS13BCDS,intron-Proximal
    HLTFchr21140890411408961-3.726938.23533HepG2ROCK2intron-Distal
    HLTFchr222477160224771655+4.794616.20441HepG2SPECC1L-ADORA2A, SPECC1Lintron-Distal
    HLTFchr158612474686124807+3.089503.07152HepG2AKAP13CDS
    HLTFchr5172346300172346344+3.608484.70379HepG2ERGIC1intron-Distal
    HLTFchr7158486005158486085-3.342085.20589K562NCAPG2CDS,intron-Distal,intron-Proximal
    HLTFchr7100732585100732651+3.765348.01794HepG2TRIM56CDS,intron-Distal
    HLTFchr64794329747943414-3.154227.74754HepG2PTCHD4intron-Distal
    HLTFchr135087392950874044+4.1198410.87618HepG2DLEU1intron-Distal
    HLTFchr176642005666420125+3.206025.70801HepG2RP11-120M18.2intron-Distal
    HLTFchrX133021788133021845-3.3688810.86675HepG2GPC3intron-Distal
    HLTFchr1227335175227335249-3.226343.34920HepG2CDC42BPACDS,intron-Distal
    HLTFchr6144768801144768875+3.0060325.62729HepG2UTRNCDS
    HLTFchr76445518764455245-3.988329.67879HepG2ERV3-1, ZNF117intron-Distal




    24 proteins are bound to HLTF RNA:

    Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
    chr3148748131148748175-3'-UTR,intron-Distal4.221287.24422K562PUM2
    chr3148747966148748010-3'-UTR,intron-Distal4.7470510.86757K562PABPC4
    chr3148748334148748473-3'-UTR,intron-Distal,intron-Proximal3.395689.19986K562IGF2BP1
    chr3148748131148748176-3'-UTR,intron-Distal4.237774.43122HepG2SUB1
    chr3148748126148748207-3'-UTR,intron-Distal3.805267.05443K562KHSRP
    chr3148748098148748128-3'-UTR,intron-Distal4.282249.84602K562PABPC4
    chr3148804186148804233-5'-UTR,intron-Distal5.182677.58445K562RBM15
    chr3148804170148804234-5'-UTR,intron-Distal3.960174.46401K562DDX3X
    chr3148804254148804310-5'-UTR,intron-Distal,intron-Proximal4.770923.69821K562DDX3X
    chr3148789059148789073-CDS,intron-Distal4.054103.38968HepG2BCLAF1
    chr3148789368148789425-CDS,intron-Distal,intron-Proximal3.110749.52037K562ZNF622
    chr3148768018148768037-CDS,intron-Distal,intron-Proximal4.440435.21253K562LIN28B
    chr3148757433148757478-CDS,intron-Distal3.070615.00751HepG2BCLAF1
    chr3148757817148757899-CDS,intron-Distal,intron-Proximal3.4409714.42791K562DDX24
    chr3148778627148778639-CDS,intron-Distal4.359823.06595HepG2BCLAF1
    chr3148766751148766800-CDS,intron-Distal,intron-Proximal3.630635.02403K562SF3B4
    chr3148759362148759451-CDS,intron-Distal3.400174.05316K562GRWD1
    chr3148757822148757892-CDS,intron-Distal,intron-Proximal3.328927.93794HepG2BCLAF1
    chr3148766720148766760-CDS,intron-Distal3.592713.91115K562LIN28B
    chr3148773100148773186-CDS,intron-Distal3.3200011.95094K562DDX24
    chr3148757446148757475-CDS,intron-Distal3.702734.71060K562BUD13
    chr3148773089148773132-CDS,intron-Distal,intron-Proximal3.9083911.62230K562UCHL5
    chr3148791029148791089-CDS,intron-Distal3.514445.45876HepG2BCLAF1
    chr3148773090148773122-CDS,intron-Distal4.7328811.26582K562ZNF622
    chr3148750079148750133-CDS,intron-Distal3.438445.45876HepG2BCLAF1
    chr3148789045148789118-CDS,intron-Distal4.0239113.59989K562ZNF622
    chr3148789369148789410-CDS,intron-Distal,intron-Proximal3.384185.15500HepG2BCLAF1
    chr3148781218148781247-CDS,intron-Distal3.720393.87469HepG2BCLAF1
    chr3148791972148792014-CDS,intron-Distal,intron-Proximal3.323884.43583K562GPKOW
    chr3148789136148789230-CDS,intron-Distal3.4396216.81987K562ZNF622
    chr3148793682148793737-CDS,intron-Distal3.283857.28455K562ZNF622
    chr3148778613148778693-CDS,intron-Distal,intron-Proximal4.0043814.54734K562SF3B4
    chr3148793683148793727-CDS,intron-Distal4.916556.37937HepG2BCLAF1
    chr3148765834148765885-CDS,intron-Distal3.203703.94979HepG2BCLAF1
    chr3148804089148804105-CDS,intron-Distal3.429353.08090K562AQR
    chr3148773089148773179-CDS,intron-Distal,intron-Proximal4.876039.74753HepG2BCLAF1
    chr3148802465148802539-CDS,intron-Distal,intron-Proximal3.749847.65019K562LIN28B
    chr3148782647148782700-CDS,intron-Distal,intron-Proximal4.1792213.11913K562KHSRP
    chr3148766760148766789-CDS,intron-Distal,intron-Proximal5.382839.44026K562LIN28B
    chr3148778402148778507-CDS,intron-Distal,intron-Proximal4.9815719.00393K562EFTUD2
    chr3148793667148793754-CDS,intron-Distal,intron-Proximal3.223528.91678K562UCHL5
    chr3148791011148791063-CDS,intron-Distal,intron-Proximal3.507606.28780K562DDX24
    chr3148785966148786030-CDS,intron-Distal,intron-Proximal3.334663.67092K562PRPF8
    chr3148802465148802518-CDS,intron-Distal,intron-Proximal3.176663.55800HepG2BCLAF1
    chr3148792005148792095-CDS,intron-Distal3.3397612.80038K562ZNF622
    chr3148793572148793620-intron-Distal,intron-Proximal4.238343.89565K562PRPF8
    chr3148759798148759868-intron-Distal,intron-Proximal3.234653.47285K562PRPF8
    chr3148786133148786176-intron-Distal,intron-Proximal4.861685.40008K562SF3B4
    chr3148759805148759911-intron-Distal,intron-Proximal3.436357.21887K562KHSRP
    chr3148798728148798780-intron-Distal3.971558.47371K562KHSRP
    chr3148790891148790975-intron-Distal,intron-Proximal3.166263.07751K562KHSRP
    chr3148782701148782728-intron-Distal,intron-Proximal4.026488.44734K562KHSRP
    chr3148802082148802136-intron-Distal4.091993.24603K562KHSRP
    chr3148778334148778413-intron-Distal,intron-Proximal3.665395.98773K562KHSRP
    chr3148772748148772890-intron-Distal3.5888611.04913K562KHSRP
    chr3148772117148772183-intron-Distal4.524603.42734K562PTBP1
    chr3148778345148778407-intron-Distal,intron-Proximal4.559684.85612K562PRPF8
    chr3148772752148772828-intron-Distal4.356824.98857K562TIA1
    chr3148772102148772162-intron-Distal4.873846.51010K562MATR3
    chr3148751188148751290-intron-Distal3.082313.28806K562KHSRP
    chr3148770383148770416-intron-Distal4.394174.47026K562MATR3
    chr3148785970148786022-intron-Distal,intron-Proximal4.030164.49024K562AQR
    chr3148800411148800465-intron-Distal4.287397.90970K562KHSRP
    chr3148785677148785780-intron-Distal3.533843.84723K562ILF3
    chr3148781312148781370-intron-Distal,intron-Proximal4.3571610.42818K562SF3B4
    chr3148771946148772024-intron-Distal4.029844.93238K562QKI
    chr3148770416148770483-intron-Distal4.878487.35792K562MATR3
    chr3148757750148757808-intron-Distal,intron-Proximal3.831154.89208K562AQR
    chr3148798652148798728-intron-Distal3.810738.11893K562KHSRP
    chr3148768781148768921-intron-Distal3.9480213.48717K562MATR3
    chr3148785007148785101-intron-Distal3.237807.63715K562KHSRP
    chr3148793600148793662-intron-Distal,intron-Proximal5.208595.69951K562AQR
    chr3148798803148798884-intron-Distal3.219585.96041K562KHSRP
    chr3148772230148772295-intron-Distal4.137624.18579K562MATR3
    chr3148759637148759714-intron-Distal3.7138311.99390K562KHSRP
    chr3148785872148785942-intron-Distal,intron-Proximal4.847435.50285K562PRPF8
    chr3148770331148770383-intron-Distal3.154033.18966K562MATR3
    chr3148768785148768929-intron-Distal4.437713.27829HepG2MATR3
    chr3148804030148804089-intron-Distal5.556757.63570K562AQR
    chr3148778965148779034-intron-Distal4.001773.57543K562ILF3
    chr3148759597148759637-intron-Distal4.466226.07567K562KHSRP
    ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




    No autoregularoty interactions between protein HLTF and its RNA.



    Diffrential Expression
    • 1,245 differentially expressed genes after Knockdown/Knockout HLTF protein.  





    • 107 RBPs can affect the levels of HLTF.  







    1,245 differentially expressed genes after Knockdown/Knockout HLTF protein :

    Only display 100 entries as example. Please click "View All" button to see all 1,245 entries.     

    Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
    C1orf112ENSG00000000460.12255.15970404.61950-0.665202.848801.45780HepG2HLTF
    STPG1ENSG00000001460.13148.6011082.849700.842802.643001.31460HepG2HLTF
    TFPIENSG00000003436.1016163.590209632.426100.746705.418303.41730HepG2HLTF
    DVL2ENSG00000004975.7311.76760659.03050-1.079903.210101.70860HepG2HLTF
    CROTENSG00000005469.7381.76850213.481700.838504.039202.34190HepG2HLTF
    ZFXENSG00000005889.111404.84800968.609700.536302.680001.34100HepG2HLTF
    TMEM98ENSG00000006042.7996.144501445.07740-0.536702.685401.34490HepG2HLTF
    ALDH3B1ENSG00000006534.1152.51380123.83640-1.237704.077802.36630HepG2HLTF
    IFRD1ENSG00000006652.9799.65720515.983600.632003.262001.74490HepG2HLTF
    ARSDENSG00000006756.11522.07660299.304800.802504.234702.48650HepG2HLTF
    E2F2ENSG00000007968.6115.00910213.77990-0.894403.430301.86820HepG2HLTF
    JARID2ENSG00000008083.9585.47290881.97510-0.591102.991501.55080HepG2HLTF
    AASSENSG00000008311.10261.59820582.36290-1.154607.495105.14390HepG2HLTF
    IL32ENSG00000008517.123030.896101925.666700.654304.165902.43370HepG2HLTF
    SEC62ENSG00000008952.123933.079302735.766600.523602.807401.42770HepG2HLTF
    RPS20ENSG00000008988.53996.142905785.75540-0.533902.991201.55080HepG2HLTF
    CD9ENSG00000010278.7397.22610248.735500.675202.945801.51800HepG2HLTF
    NCAPD2ENSG00000010292.82485.882403702.06900-0.574603.283001.76230HepG2HLTF
    TSPAN9ENSG00000011105.7403.86580888.36860-1.137308.848906.30010HepG2HLTF
    ANLNENSG00000011426.61597.774802418.15210-0.597803.447201.87990HepG2HLTF
    QPCTLENSG00000011478.7157.62900353.28510-1.164303.444701.87920HepG2HLTF
    MBTPS2ENSG00000012174.71301.84980824.340700.659203.713602.09120HepG2HLTF
    NR1H4ENSG00000012504.9551.23340923.85700-0.745004.373302.59830HepG2HLTF
    KDM5DENSG00000012817.112085.200901425.121400.549002.972501.53810HepG2HLTF
    RNF14ENSG00000013561.13458.12050264.693900.791303.937002.26240HepG2HLTF
    DDX11ENSG00000013573.12362.12940611.27690-0.755303.991202.30600HepG2HLTF
    POLA2ENSG00000014138.4213.65950380.69110-0.833304.002702.31240HepG2HLTF
    RGPD5ENSG00000015568.8192.74320407.73220-1.080905.145703.21360HepG2HLTF
    CYP24A1ENSG00000019186.5799.86730349.715901.193503.103801.63590HepG2HLTF
    CYP3A43ENSG00000021461.12112.5247038.786901.536505.306203.32690HepG2HLTF
    GRAMD1BENSG00000023171.1024.677903.514202.811903.529801.94060HepG2HLTF
    BIRC3ENSG00000023445.9174.8012087.426500.999503.692702.07490HepG2HLTF
    NCAPH2ENSG00000025770.14182.69180338.81830-0.891103.065701.60530HepG2HLTF
    FASENSG00000026103.15328.78230196.469900.742703.124101.64810HepG2HLTF
    ARNTL2ENSG00000029153.10487.99460311.562700.647202.967401.53360HepG2HLTF
    TMSB10ENSG00000034510.46710.390304520.012000.570003.418401.86100HepG2HLTF
    SH3YL1ENSG00000035115.171371.65830773.324000.826705.532403.51250HepG2HLTF
    TIMP2ENSG00000035862.82715.550801353.055101.004908.663506.14030HepG2HLTF
    CDH1ENSG00000039068.142760.637801044.766501.401703.565101.96770HepG2HLTF
    DNAH5ENSG00000039139.948.761006.953802.809706.278104.10870HepG2HLTF
    C6ENSG00000039537.974.8298012.406902.592408.176505.73250HepG2HLTF
    PHLPP2ENSG00000040199.14820.94970551.843600.572902.732501.37530HepG2HLTF
    TDP1ENSG00000042088.9311.08520569.78730-0.873104.975803.06840HepG2HLTF
    AIFM2ENSG00000042286.10412.88490668.96760-0.696202.774601.40720HepG2HLTF
    RETSATENSG00000042445.92330.064301584.611900.556103.082701.61920HepG2HLTF
    FAM214AENSG00000047346.8616.75550400.723400.622002.870801.46910HepG2HLTF
    RRM2BENSG00000048392.72003.967601043.554700.941307.382805.03980HepG2HLTF
    KITLGENSG00000049130.9310.95400184.510200.752903.158801.67130HepG2HLTF
    ADAMTS6ENSG00000049192.10666.06760342.790200.958206.087203.94680HepG2HLTF
    RCN1ENSG00000049449.42271.654301286.016500.820705.928703.82290HepG2HLTF
    CLPTM1LENSG00000049656.9609.99330985.84340-0.692603.898402.23090HepG2HLTF
    LIMA1ENSG00000050405.91435.89440933.513500.621103.443001.87820HepG2HLTF
    FOXN3ENSG00000053254.112182.486704419.49520-1.017909.262806.63490HepG2HLTF
    FAM168AENSG00000054965.6822.393101360.23380-0.726004.470502.67400HepG2HLTF
    RELTENSG00000054967.840.4854092.07790-1.185503.182401.68800HepG2HLTF
    GINM1ENSG00000055211.81138.89330707.271100.687203.921702.25060HepG2HLTF
    MRPL43ENSG00000055950.12179.10520298.04610-0.734702.897301.48610HepG2HLTF
    ITIH1ENSG00000055957.6215.42660387.01060-0.845203.495601.91690HepG2HLTF
    USP13ENSG00000058056.42359.168701610.910600.550302.925301.50510HepG2HLTF
    RASGRF1ENSG00000058335.1139.3132011.782401.738302.886201.47800HepG2HLTF
    SLC2A3ENSG00000059804.115307.4933013307.72640-1.3262012.204909.28380HepG2HLTF
    SNRNP40ENSG00000060688.8495.40410780.85410-0.656403.356301.81080HepG2HLTF
    CSENSG00000062485.144486.665806848.02130-0.610003.823502.18110HepG2HLTF
    VMP1ENSG00000062716.65993.681103686.134400.701204.731502.87240HepG2HLTF
    CASP8ENSG00000064012.171331.73270852.724300.643103.611302.00500HepG2HLTF
    SPA17ENSG00000064199.2234.53210128.842200.864103.446101.87990HepG2HLTF
    SLC12A2ENSG00000064651.9624.25250363.184900.781302.985801.54750HepG2HLTF
    CNN2ENSG00000064666.10880.453101482.82860-0.752003.040401.58540HepG2HLTF
    TRAM2ENSG00000065308.43172.840004864.48490-0.616503.830402.18440HepG2HLTF
    GSTO2ENSG00000065621.1075.4072028.654401.395803.494201.91620HepG2HLTF
    FAM107BENSG00000065809.91278.45790844.166500.598703.200801.70060HepG2HLTF
    SP100ENSG00000067066.12801.91420464.874100.786504.556002.74520HepG2HLTF
    KLF6ENSG00000067082.103234.373202266.035200.513202.679901.34100HepG2HLTF
    PKMENSG00000067225.1317015.3408025086.90470-0.560103.352501.80900HepG2HLTF
    FGFR3ENSG00000068078.131633.798803115.16430-0.931102.963301.53050HepG2HLTF
    PLEKHH3ENSG00000068137.1054.54340131.53580-1.270002.846901.45630HepG2HLTF
    NUCKS1ENSG00000069275.124985.262907027.46390-0.495302.695901.35130HepG2HLTF
    JMJD6ENSG00000070495.10410.75040716.74130-0.803204.749502.88500HepG2HLTF
    WIPI1ENSG00000070540.81134.07320761.512900.574502.897901.48610HepG2HLTF
    CDC42ENSG00000070831.115380.293503733.374700.527102.893801.48310HepG2HLTF
    SLC12A3ENSG00000070915.59.2903033.29660-1.841602.792401.41800HepG2HLTF
    HLTFENSG00000071794.11343.391301084.66300-1.6593012.215109.28380HepG2HLTF
    RDH11ENSG00000072042.83806.531702394.859100.668404.254402.50100HepG2HLTF
    LNX1ENSG00000072201.934.878008.053702.114503.425201.86490HepG2HLTF
    XRCC1ENSG00000073050.7309.79930502.88620-0.698902.892501.48220HepG2HLTF
    SCARB1ENSG00000073060.114448.105006639.65980-0.577903.463101.89420HepG2HLTF
    MCM2ENSG00000073111.9506.566501705.22020-1.751104.587102.76780HepG2HLTF
    CDHR2ENSG00000074276.6373.66790705.70380-0.917305.545503.52170HepG2HLTF
    ENO1ENSG00000074800.939177.9739058263.34910-0.572503.517801.93200HepG2HLTF
    SEMA3AENSG00000075213.6106.3399042.562001.320904.176602.43980HepG2HLTF
    GTSE1ENSG00000075218.14247.73270421.50980-0.766803.618102.00950HepG2HLTF
    MCM6ENSG00000076003.4460.79730831.43380-0.851505.358403.36300HepG2HLTF
    SPAG5ENSG00000076382.12893.522501645.06210-0.880606.380604.19130HepG2HLTF
    UBE2TENSG00000077152.5366.53830577.18900-0.655103.105401.63650HepG2HLTF
    DNAJC10ENSG00000077232.125643.247503430.491500.718004.962603.05670HepG2HLTF
    SNRPAENSG00000077312.4522.40030939.59970-0.846905.459003.45430HepG2HLTF
    GPR137BENSG00000077585.9105.4826049.404101.094203.122301.64720HepG2HLTF
    FGFR1ENSG00000077782.15953.550801835.32180-0.944704.690602.84080HepG2HLTF
    C12orf5ENSG00000078237.4296.73860111.243101.415408.512606.00770HepG2HLTF
    CEACAM1ENSG00000079385.178261.337605801.785100.509802.774801.40720HepG2HLTF
    Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

    *: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
    **: "-log(0)" was displayed as "99999.99999".





    107 RBPs can affect the gene expression of HLTF :

    Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
    HLTFENSG00000071794.11726.71060914.43010-0.331503.500902.83090HepG2ACO1
    HLTFENSG00000071794.11850.964001299.18510-0.610404.752303.73490HepG2ASCC1
    HLTFENSG00000071794.11495.97600816.84370-0.719805.475904.14360HepG2BCCIP
    HLTFENSG00000071794.11556.17110903.91060-0.700707.491706.56580HepG2BOP1
    HLTFENSG00000071794.11717.50050917.18560-0.354202.477901.74500HepG2CALR
    HLTFENSG00000071794.11810.591901234.29970-0.606605.264504.21550HepG2CIRBP
    HLTFENSG00000071794.11762.95480914.33580-0.261102.475801.83960HepG2CKAP4
    HLTFENSG00000071794.111266.24330829.852100.609506.552805.52750HepG2CPSF6
    HLTFENSG00000071794.11807.009501231.87460-0.6102010.422509.33010HepG2CELF1
    HLTFENSG00000071794.111117.278201324.77210-0.245803.153002.36950HepG2DAZAP1
    HLTFENSG00000071794.111285.52030920.059600.482504.346203.08840HepG2DDX5
    HLTFENSG00000071794.11955.320301291.85440-0.435402.848402.22220HepG2DDX6
    HLTFENSG00000071794.11658.07240837.41570-0.347703.917603.16890HepG2DNAJC2
    HLTFENSG00000071794.11583.60530895.16600-0.617202.294601.45320HepG2EEF2
    HLTFENSG00000071794.11700.839301372.82100-0.970009.689208.50590HepG2EIF4A3
    HLTFENSG00000071794.111331.186001642.01790-0.302803.620402.94690HepG2ETF1
    HLTFENSG00000071794.11654.80030940.73730-0.522703.487502.77500HepG2GPKOW
    HLTFENSG00000071794.111068.01040873.082300.290602.994801.98100HepG2HDGF
    HLTFENSG00000071794.11343.391301084.66300-1.6593012.215109.28380HepG2HLTF
    HLTFENSG00000071794.11535.28930852.93800-0.672107.172106.20420HepG2HNRNPA1
    HLTFENSG00000071794.11388.69250948.74650-1.2874021.6725019.93290HepG2HNRNPC
    HLTFENSG00000071794.11538.30580649.83440-0.271601.913601.30970HepG2HNRNPF
    HLTFENSG00000071794.111032.370001300.49800-0.333102.311601.66970HepG2HNRNPK
    HLTFENSG00000071794.11794.310501206.82800-0.6034012.7675011.41700HepG2HNRNPL
    HLTFENSG00000071794.11486.29200688.69260-0.502004.253903.09970HepG2HNRNPM
    HLTFENSG00000071794.11732.16780942.47320-0.364303.968203.25310HepG2HNRNPU
    HLTFENSG00000071794.11502.88340639.90080-0.347602.464901.78010HepG2IGF2BP1
    HLTFENSG00000071794.11656.893701305.99510-0.9914010.062308.86050HepG2IGF2BP2
    HLTFENSG00000071794.11810.30760962.70330-0.248602.474401.77730HepG2ILF2
    HLTFENSG00000071794.11817.655001556.95330-0.929208.863107.37240HepG2LARP4
    HLTFENSG00000071794.11680.521501385.24560-1.0254012.7462011.37750HepG2MAGOH
    HLTFENSG00000071794.11648.318701393.05640-1.1035013.2650011.95760HepG2MATR3
    HLTFENSG00000071794.11439.35780760.68350-0.791903.633102.43440HepG2METAP2
    HLTFENSG00000071794.111368.25110807.843700.7601011.006009.50390HepG2MSI2
    HLTFENSG00000071794.111115.975801425.91760-0.353602.230701.65910HepG2NCBP2
    HLTFENSG00000071794.11974.914001313.63040-0.430205.377104.32020HepG2NOL12
    HLTFENSG00000071794.111042.16680796.010000.388602.148501.48640HepG2NSUN2
    HLTFENSG00000071794.11602.02270932.87370-0.631909.577708.15660HepG2PARN
    HLTFENSG00000071794.11876.425101236.12850-0.496107.761706.82710HepG2PCBP1
    HLTFENSG00000071794.11909.25970703.712100.369603.784202.89270HepG2PRPF4
    HLTFENSG00000071794.111000.77830619.593500.691606.702805.50710HepG2PRPF8
    HLTFENSG00000071794.111089.566401257.77370-0.207101.797201.33730HepG2PTBP1
    HLTFENSG00000071794.111054.025601253.91840-0.250501.848601.34770HepG2PUF60
    HLTFENSG00000071794.111056.318801331.02330-0.333505.146304.38910HepG2PUM1
    HLTFENSG00000071794.112274.706701362.270900.7396015.7952014.48080HepG2QKI
    HLTFENSG00000071794.11719.919101035.14030-0.523901.939501.33880HepG2RAVER1
    HLTFENSG00000071794.11731.702801372.40900-0.9074019.9571018.82640HepG2RBM22
    HLTFENSG00000071794.111143.688801399.80900-0.291503.201302.62780HepG2NELFE
    HLTFENSG00000071794.11436.64600700.04020-0.681006.501405.51810HepG2RPLP0
    HLTFENSG00000071794.11405.73060707.08960-0.801404.328203.57590HepG2RPS19
    HLTFENSG00000071794.111483.457501202.175800.303203.792902.99160HepG2SLBP
    HLTFENSG00000071794.11493.28050978.76410-0.9886025.0893023.46800HepG2SMN1
    HLTFENSG00000071794.11693.881201054.14240-0.603303.204002.16540HepG2SMNDC1
    HLTFENSG00000071794.111258.276501550.06050-0.300903.894503.33030HepG2SRFBP1
    HLTFENSG00000071794.111670.433501366.877400.289203.350702.84310HepG2SRSF1
    HLTFENSG00000071794.11788.924401237.98210-0.6500012.4578011.25960HepG2SRSF5
    HLTFENSG00000071794.11494.85530638.44300-0.367603.031002.30800HepG2SRSF7
    HLTFENSG00000071794.11724.53900967.96230-0.417902.574601.33660HepG2SSRP1
    HLTFENSG00000071794.11570.28890799.50650-0.487402.898902.20930HepG2SUPV3L1
    HLTFENSG00000071794.111628.679301228.535200.406705.126004.40180HepG2TAF15
    HLTFENSG00000071794.11319.80410535.89060-0.744705.145503.84780HepG2TFIP11
    HLTFENSG00000071794.11424.12960915.74880-1.1104020.9593019.82080HepG2TIAL1
    HLTFENSG00000071794.11555.70090923.97790-0.7335013.1086012.00980HepG2TRIM56
    HLTFENSG00000071794.11933.100101224.91660-0.392603.836902.79050HepG2TUFM
    HLTFENSG00000071794.11660.548201208.51440-0.871502.497201.56600HepG2U2AF2
    HLTFENSG00000071794.11724.84450921.04440-0.345603.365102.22250HepG2UTP18
    HLTFENSG00000071794.11613.88590865.13800-0.495003.743703.06360HepG2UTP3
    HLTFENSG00000071794.11975.83440694.468600.490607.157706.15950HepG2ZC3H8
    HLTFENSG00000071794.11670.54690985.52610-0.555609.530908.67000HepG2ZNF622
    HLTFENSG00000071794.113914.385404588.75140-0.229303.529902.90180K562AGGF1
    HLTFENSG00000071794.113854.859204774.75080-0.308703.032002.34750K562AKAP8L
    HLTFENSG00000071794.114032.291005009.76290-0.313104.620403.40560K562ATP5C1
    HLTFENSG00000071794.11753.726601164.83490-0.628006.835705.00350K562CCAR1
    HLTFENSG00000071794.114522.034005483.98180-0.278303.277401.97960K562CCDC124
    HLTFENSG00000071794.112967.706004040.79580-0.445305.215203.47390K562CIRBP
    HLTFENSG00000071794.113589.932104655.33100-0.374907.095305.29380K562CPEB4
    HLTFENSG00000071794.119755.147307735.112600.334605.023003.70170K562CELF1
    HLTFENSG00000071794.112325.875602858.08400-0.297302.910901.84040K562DDX3X
    HLTFENSG00000071794.114036.867305138.30610-0.348104.906703.68810K562DKC1
    HLTFENSG00000071794.112511.623303491.60420-0.475309.549208.33610K562EIF2S2
    HLTFENSG00000071794.112509.242203216.90390-0.358405.369304.27530K562EIF3G
    HLTFENSG00000071794.112473.918102986.01640-0.271402.234301.49420K562EIF4A3
    HLTFENSG00000071794.117164.256406291.002000.187402.274501.41900K562EIF4G2
    HLTFENSG00000071794.112710.779903105.33550-0.196002.017201.48450K562FXR1
    HLTFENSG00000071794.115498.997003359.614500.710806.554305.36420K562G3BP2
    HLTFENSG00000071794.113809.641803123.204900.286503.678302.37070K562GLRX3
    HLTFENSG00000071794.113918.621504653.12920-0.247902.308801.61490K562GRSF1
    HLTFENSG00000071794.11878.007402355.11800-1.423507.852104.57900K562HLTF
    HLTFENSG00000071794.113895.882503247.098800.262702.503501.48080K562HNRNPA1
    HLTFENSG00000071794.11931.270202261.75600-1.2802035.2682033.22500K562HNRNPC
    HLTFENSG00000071794.111453.260202019.70270-0.474805.693103.97220K562HNRNPF
    HLTFENSG00000071794.112221.036504353.31580-0.9709025.2140022.20670K562HNRNPL
    HLTFENSG00000071794.111779.254202614.56030-0.555305.538704.16120K562HNRNPM
    HLTFENSG00000071794.114194.835503595.737500.222202.411701.57700K562HNRNPU
    HLTFENSG00000071794.113336.309704309.76890-0.369403.797102.86890K562HSPD1
    HLTFENSG00000071794.112991.477903769.45270-0.333502.182401.30200K562IGF2BP2
    HLTFENSG00000071794.111598.720601216.908700.393602.886101.35670K562ILF3
    HLTFENSG00000071794.112766.188603962.34180-0.518507.662406.23760K562MAGOH
    HLTFENSG00000071794.113856.588204850.58820-0.330803.768902.44960K562MAK16
    HLTFENSG00000071794.112225.337203954.42430-0.8294019.0093016.52850K562MATR3
    HLTFENSG00000071794.112298.611102745.24700-0.256202.115501.34880K562METAP2
    HLTFENSG00000071794.114062.690003283.635000.307005.717204.58240K562MTPAP
    HLTFENSG00000071794.112760.348504142.67900-0.585702.634501.67330K562PABPN1
    HLTFENSG00000071794.113849.953502921.933500.397803.373202.45470K562PCBP3
    HLTFENSG00000071794.112824.441802241.258000.333603.856102.90310K562POLR2G
    HLTFENSG00000071794.112785.649003608.49900-0.373403.629602.67100K562PPIG
    HLTFENSG00000071794.111553.201202027.88780-0.384703.379002.36500K562PSIP1
    HLTFENSG00000071794.112690.720903849.60380-0.516708.291707.18330K562PTBP1
    HLTFENSG00000071794.113844.025304613.83590-0.263303.359102.71580K562RBM15
    HLTFENSG00000071794.112689.501803691.74470-0.457005.378504.16060K562RBM22
    HLTFENSG00000071794.112440.928105096.78770-1.062206.539603.89040K562RBM39
    HLTFENSG00000071794.111249.439901850.12010-0.566308.270806.55390K562RCC2
    HLTFENSG00000071794.113101.326503884.86920-0.325002.350001.36050K562NELFE
    HLTFENSG00000071794.112014.297802774.73360-0.462104.512703.19620K562RPS3
    HLTFENSG00000071794.113409.951902531.868200.429402.940301.56970K562RRP9
    HLTFENSG00000071794.112760.210703494.81540-0.340403.090802.18460K562SF3B4
    HLTFENSG00000071794.111119.137501753.87110-0.648208.645806.54760K562SRFBP1
    HLTFENSG00000071794.112461.819903773.80590-0.6163011.290309.87270K562SRSF1
    HLTFENSG00000071794.114117.521903318.246700.311304.458202.77830K562SSB
    HLTFENSG00000071794.114911.095903814.740400.364403.045401.72340K562STAU1
    HLTFENSG00000071794.112941.319403819.53010-0.376903.516202.71520K562TARDBP
    HLTFENSG00000071794.112816.217403684.31760-0.387605.029303.87370K562TIA1
    HLTFENSG00000071794.111620.791302072.07830-0.354403.145702.12430K562TRIM56
    HLTFENSG00000071794.112579.159103258.14080-0.337102.346001.34980K562U2AF1
    HLTFENSG00000071794.113355.802103868.53250-0.205102.906302.17030K562UPF1
    HLTFENSG00000071794.113962.198503310.186700.259302.469801.64080K562WDR3
    HLTFENSG00000071794.114093.696503442.171600.250004.372403.32690K562WDR43
    Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

    *: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
    **: "-log(0)" was displayed as "99999.99999".





    179 alternative splicing events after Knockdown/Knockout HLTF protein :

    Only display 100 entries as example. Please click "View All" button to see all 179 entries.     

    Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
    SEITFG3ENSG00000167930.11chr16+2982422983962848422848562995472996530.212000.000060.05056includedHepG2HLTF
    SEPQLC1ENSG00000122490.14chr18-7769022777690311776791837767940077703328777034620.240000.000000.00334includedHepG2HLTF
    SEA1CFENSG00000148584.10chr10-5262379252623840526196015261974552645340526454350.059000.000060.05056includedHepG2HLTF
    SEAHSGENSG00000145192.8chr3+1863376451863377021863362851863364261863383741863390890.052000.000000.00000includedHepG2HLTF
    SEFIP1L1ENSG00000145216.11chr4+5424523954245284542440055424409054245391542454310.307000.000070.05116includedHepG2HLTF
    SESAT1ENSG00000130066.12chrX+2380241023802520238019162380200023803444238035460.070000.000000.00334includedHepG2HLTF
    SERNH1ENSG00000023191.12chr11-5048235049965020615022495071125072180.307000.000000.00268includedHepG2HLTF
    SEMORF4L2ENSG00000123562.12chrX-1029396081029396571029334261029335791029400981029401880.179000.000000.00070includedHepG2HLTF
    SESH3D19ENSG00000109686.12chr4-1520653711520654401520650611520652021520690731520693380.190000.000000.00561includedHepG2HLTF
    SEVDAC2ENSG00000165637.9chr10+7697764576977749769737787697382876978820769789730.065000.000000.00334includedHepG2HLTF
    SEMITD1ENSG00000158411.6chr2-9978987699789965997879729978810999790377997904790.142000.000030.03407includedHepG2HLTF
    SETIA1ENSG00000116001.11chr2-7045547570455594704548667045495470456190704562230.157000.000080.05731includedHepG2HLTF
    SEESYT2ENSG00000117868.11chr7-1585454711585455341585423391585424141585521761585522720.409000.000000.00000includedHepG2HLTF
    SEFLNBENSG00000136068.10chr3+5812758458127656581240085812425658128376581284790.152000.000000.00334includedHepG2HLTF
    SENUP62ENSG00000213024.6chr19-5043095050431072504122305041314150432582504327610.261000.000050.04845includedHepG2HLTF
    SEANKRD11ENSG00000167522.10chr16-8935808889358207893574208935759189371613893717520.252000.000160.09822includedHepG2HLTF
    SEBPIFB2ENSG00000078898.6chr20+3159600531596184315954053159556631596346315964890.316000.000060.05056includedHepG2HLTF
    SEBPIFB2ENSG00000078898.6chr20+3160909531609150316083473160839331609528316096050.057000.000160.09946includedHepG2HLTF
    SEPTPRSENSG00000105426.10chr19-5218797521880952184305218543521932052194780.261000.000010.01145includedHepG2HLTF
    SERRBP1ENSG00000125844.11chr20-1766064317660720176406241764117317662672176629280.193000.000010.00795includedHepG2HLTF
    SECTSBENSG00000164733.16chr8-1172188411721972117108371171098811725509117255490.148000.000060.04952includedHepG2HLTF
    SEMAP3K7ENSG00000135341.13chr6-9125427091254351912460559124612091256976912571060.421000.000000.00334includedHepG2HLTF
    SEDDX42ENSG00000198231.8chr17+6185246761852538618512226185173661864393618646300.233000.000160.09946includedHepG2HLTF
    SEGPR126ENSG00000112414.10chr6+1427048961427049801427030871427031561427113941427114800.257000.000000.00005includedHepG2HLTF
    SEGPR126ENSG00000112414.10chr6+1427620441427620901427593481427595011427644731427674030.162000.000000.00003includedHepG2HLTF
    SEELF1ENSG00000120690.9chr13-4159336341593568415561184155641841634973416355760.278000.000100.06549includedHepG2HLTF
    SEARPC3ENSG00000111229.11chr12-1108744691108744881108739821108740091108748881108749570.063000.000060.05056includedHepG2HLTF
    SEHOXD-AS1ENSG00000224189.2chr2-1770424381770425841770420591770422221770531461770532590.343000.000090.06383includedHepG2HLTF
    SEARPC1BENSG00000130429.8chr7+9897496098975078989723529897240498983324989834010.228000.000010.01145includedHepG2HLTF
    SERRN3ENSG00000085721.8chr16-1518022115180311151799851518011515185171151852280.194000.000030.03170includedHepG2HLTF
    SECRLF1ENSG00000006016.6chr19-1871271618712815187105091871065618717351187176600.190000.000000.00334includedHepG2HLTF
    SENFAT5ENSG00000102908.16chr16+6968041969680481696603056966043169680930696814890.374000.000000.00174includedHepG2HLTF
    SENEDD4LENSG00000049759.12chr18+5600270956002769560010495600112456008269560084010.280000.000110.07159includedHepG2HLTF
    SEEPB41L2ENSG00000079819.12chr6-1311978131311979151311907981311912661311992431311993900.229000.000040.04236includedHepG2HLTF
    SEMARCH8ENSG00000165406.11chr10-4608597146086022460285574602873746089682460903540.320000.000080.05731includedHepG2HLTF
    SENEU4ENSG00000204099.7chr2+242750876242751020242750329242750369242755678242755882-0.069000.000020.02429excludedHepG2HLTF
    SELMO7ENSG00000136153.15chr13+763832897638331976378424763786777639129676391414-0.468000.000000.00000excludedHepG2HLTF
    SENASPENSG00000132780.12chr1+460729924607400946072153460722634607884046078920-0.116000.000080.05731excludedHepG2HLTF
    SEFLNBENSG00000136068.10chr3+581164675811663558112328581124895811853458118658-0.115000.000080.05731excludedHepG2HLTF
    SEDHRS2ENSG00000100867.10chr14+241080492410821324105575241059812410838724108565-0.174000.000000.00003excludedHepG2HLTF
    SENOP56ENSG00000101361.10chr20+263678326368602636579263668026370462637195-0.148000.000000.00080excludedHepG2HLTF
    SEUTRNENSG00000152818.14chr6+145148483145148522145142017145142154145148746145148812-0.116000.000000.00163excludedHepG2HLTF
    SEFGL1ENSG00000104760.12chr8-177491891774931617743000177430801775273317752913-0.066000.000170.09946excludedHepG2HLTF
    SEAGPAT1ENSG00000204310.6chr6-321435903214372232139073321392823214428632144857-0.355000.000040.04236excludedHepG2HLTF
    SEAPLP2ENSG00000084234.12chr11+129993506129993674129992199129992408129996594129996725-0.063000.000130.08265excludedHepG2HLTF
    SEDEF8ENSG00000140995.12chr16+900158249001592190015202900152229002065090020784-0.319000.000160.09822excludedHepG2HLTF
    SETSNAXENSG00000116918.9chr1+2316992102316993752316968732316970012317002732317022700.082000.000070.05632includedK562HLTF
    SEBAG6ENSG00000204463.8chr6-3160727631607423316068043160700331607975316080830.136000.000100.06625includedK562HLTF
    SESDHAP1ENSG00000185485.10chr3-1956871701956872941956866181956869571956901701956902920.352000.000090.06625includedK562HLTF
    SESNHG8ENSG00000269893.2chr4+1192000981192002921191999121191999471192005431192005860.093000.000070.05812includedK562HLTF
    SEREPIN1ENSG00000214022.7chr7+1500667591500669571500658881500660301500678481500679730.253000.000070.05632includedK562HLTF
    SEELOVL5ENSG00000012660.9chr6-5315906353159289531565735315676153160439531605050.085000.000010.00884includedK562HLTF
    SEHNRNPDLENSG00000152795.13chr4-8334671583346820833457818334603683347189833473030.122000.000010.00971includedK562HLTF
    SEHMGA1ENSG00000137309.15chr6+3420498034205094342046493420474034208513342086590.146000.000140.07788includedK562HLTF
    SEINTS12ENSG00000138785.10chr4-1066248041066249661066210061066211711066297941066298380.303000.000130.07435includedK562HLTF
    SEMETTL1ENSG00000037897.12chr12-5816526258165388581648765816504058165756581658990.278000.000000.00004includedK562HLTF
    SEPDE4AENSG00000065989.11chr19+1056832510568456105655041056559810568554105687780.150000.000120.07331includedK562HLTF
    SEMSMO1ENSG00000052802.8chr4+1662544911662547771662488721662489161662589401662590890.137000.000000.00008includedK562HLTF
    SERPL17ENSG00000265681.2chr18-4701810547018203470179014701795447018644470187690.164000.000090.06625includedK562HLTF
    SEEZH2ENSG00000106462.6chr7-1485339131485340921485297251485298421485435611485436790.139000.000160.08128includedK562HLTF
    SEMAPK9ENSG00000050748.13chr5-1797067951797070361796962791796964091797074391797076080.144000.000110.07119includedK562HLTF
    SECENPEENSG00000138778.7chr4-1040609451040612361040595071040596061040614121040615710.503000.000000.00084includedK562HLTF
    SERPS24ENSG00000138326.14chr10+7979996179799983797969517979706279800372798004550.054000.000060.05609includedK562HLTF
    SEAC079466.1ENSG00000266976.1chr19+291028182910306129097594290980112910334529106136-0.153000.000000.00049excludedK562HLTF
    SERNF34ENSG00000170633.12chr12+121840544121840610121837921121838021121853961121854180-0.108000.000170.08403excludedK562HLTF
    SEPRDM2ENSG00000116731.18chr1+140956121409566814075855140759821409957214099621-0.143000.000060.05106excludedK562HLTF
    SEFKBP14ENSG00000106080.6chr7-300598283005992030058611300587393006228030062432-0.190000.000040.03945excludedK562HLTF
    SEELL2ENSG00000118985.10chr5-952683359526841795255127952552499527870595278753-0.210000.000000.00045excludedK562HLTF
    SEUBE2J2ENSG00000160087.16chr1-119142411915051190284119086711923711192510-0.058000.000110.06985excludedK562HLTF
    SEEIF4HENSG00000106682.10chr7+736045767360463673604151736042487360907073609208-0.071000.000120.07331excludedK562HLTF
    SERAB1AENSG00000138069.12chr2-653181166531821265315004653158246532510465325200-0.093000.000100.06846excludedK562HLTF
    SEPTBP1ENSG00000011304.12chr19+805491805569805012805187806407806556-0.083000.000120.07243excludedK562HLTF
    SEMORF4L2ENSG00000123562.12chrX-102939608102939657102933426102933579102940098102940188-0.136000.000010.01273excludedK562HLTF
    SEBCORENSG00000183337.12chrX-399308893993094339930225399304123993160139934433-0.236000.000000.00286excludedK562HLTF
    SESZRD1ENSG00000055070.12chr1+167178691671791916693577166938031671972216719880-0.208000.000000.00045excludedK562HLTF
    SECDC42BPAENSG00000143776.14chr1-227239581227239686227235627227235711227257477227257554-0.161000.000190.09269excludedK562HLTF
    SEFLNBENSG00000136068.10chr3+581176535811774658116467581166355811853458118658-0.142000.000110.06985excludedK562HLTF
    SERIF1ENSG00000080345.13chr2+152313091152313134152311408152311673152314274152314477-0.081000.000160.08128excludedK562HLTF
    SESLMO2ENSG00000101166.11chr20-576122455761233557611744576118155761352057613689-0.103000.000010.01339excludedK562HLTF
    SEANKRD11ENSG00000167522.10chr16-893580888935818589357420893575918937161389371752-0.115000.000160.08128excludedK562HLTF
    SEU2AF1ENSG00000160201.7chr21-445205624452062944515803445158534452147544521542-0.116000.000190.09269excludedK562HLTF
    SEINSIG1ENSG00000186480.8chr7+155095534155095605155094456155094556155099950155100670-0.071000.000140.07832excludedK562HLTF
    SEXPO1ENSG00000082898.12chr2-617293836172944561726899617270296174974561749818-0.072000.000010.00971excludedK562HLTF
    SEAKAP8LENSG00000011243.13chr19-155094401550957715508524155086661551011215510221-0.060000.000010.00898excludedK562HLTF
    SEEIF4A2ENSG00000156976.10chr3+186506098186506209186505591186505671186506913186507080-0.081000.000000.00003excludedK562HLTF
    SEZMYND8ENSG00000101040.15chr20-458412864584137045839405458395424584890845848975-0.290000.000010.01339excludedK562HLTF
    SESLC7A11ENSG00000151012.9chr4-139106274139106398139104355139104459139135738139135783-0.316000.000020.01892excludedK562HLTF
    SEPCGF3ENSG00000185619.13chr4+726188726287724758724899727460727578-0.359000.000000.00466excludedK562HLTF
    SENSMFENSG00000165802.15chr9-140349690140349759140348842140348895140350862140350938-0.259000.000140.07832excludedK562HLTF
    SEC1orf63ENSG00000117616.13chr1-255709442557098925570040255701242557164025571792-0.304000.000030.02928excludedK562HLTF
    SECD97ENSG00000123146.15chr19+145071531450728514501735145018911450846914508616-0.306000.000120.07243excludedK562HLTF
    SECAPN7ENSG00000131375.5chr3+152870321528717815283684152837601528823815288301-0.272000.000030.03012excludedK562HLTF
    SEMLH1ENSG00000076242.10chr3+370837583708382237081676370817853708900937089174-0.098000.000160.08128excludedK562HLTF
    SEMETTL5ENSG00000138382.9chr2-170671986170672038170668966170669016170676070170676153-0.081000.000000.00538excludedK562HLTF
    SEIDI1ENSG00000067064.6chr10-108993810901111089240108933310948031095110-0.109000.000120.07243excludedK562HLTF
    SECALUENSG00000128595.12chr7+128388626128388858128379345128379486128398924128399091-0.147000.000100.06625excludedK562HLTF
    SESETD5ENSG00000168137.11chr3+949457194946359490071949031494954229495552-0.060000.000070.05632excludedK562HLTF
    SEMARCH7ENSG00000136536.10chr2+160621136160621185160619390160619504160623794160623880-0.105000.000180.09141excludedK562HLTF
    SEPACSIN2ENSG00000100266.13chr22-432728934327301643272142432723394327505343275175-0.142000.000020.02414excludedK562HLTF
    SEUSP8ENSG00000138592.9chr15+507764715077655850773677507742625078199750782078-0.200000.000070.05790excludedK562HLTF





    13 RBPs can affect the splicing of HLTF :

    Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
    SEHLTFENSG00000071794.11chr3-148759276148759467148757817148757943148759952148760077-0.068000.002220.03965excludedK562SRSF1
    SEHLTFENSG00000071794.11chr3-148778565148778645148778429148778474148781217148781311-0.056000.002480.04311excludedK562SF3B4
    SEHLTFENSG00000071794.11chr3-148782577148782653148781260148781311148786026148786122-0.151000.000000.00008excludedK562SF3B4
    SEHLTFENSG00000071794.11chr3-148782577148782653148781217148781311148786026148786122-0.129000.000000.00000excludedK562AKAP8L
    SEHLTFENSG00000071794.11chr3-148782577148782653148781260148781311148786026148786069-0.087000.000000.00003excludedK562AQR
    SEHLTFENSG00000071794.11chr3-148759276148759467148757817148757943148759952148760077-0.061000.002680.02793excludedK562AQR
    SEHLTFENSG00000071794.11chr3-148768018148768162148766649148766788148777504148777594-0.071000.002930.04097excludedK562PUS1
    SEHLTFENSG00000071794.11chr3-148791011148791109148789369148789444148792001148792135-0.091000.000050.00138excludedK562PUS1
    SEHLTFENSG00000071794.11chr3-148782577148782653148781217148781311148786026148786122-0.126000.000000.00000excludedK562PUS1
    SEHLTFENSG00000071794.11chr3-148759276148759455148757817148757943148759952148760077-0.056000.000120.05395excludedK562KHSRP
    SEHLTFENSG00000071794.11chr3-148791011148791109148789369148789444148792001148792135-0.067000.005730.08991excludedK562U2AF1
    SEHLTFENSG00000071794.11chr3-148782577148782653148781260148781311148786026148786122-0.222000.000000.00000excludedK562U2AF1
    SEHLTFENSG00000071794.11chr3-148782577148782653148781217148781311148786026148786122-0.133000.000000.00013excludedK562HNRNPL
    SEHLTFENSG00000071794.11chr3-148782577148782653148781217148781311148786026148786122-0.120000.000000.00002excludedK562UTP18
    SEHLTFENSG00000071794.11chr3-148778565148778645148778429148778474148781217148781311-0.074000.000240.00593excludedK562U2AF2
    SEHLTFENSG00000071794.11chr3-148791011148791109148789369148789444148792001148792135-0.117000.000040.00136excludedK562U2AF2
    SEHLTFENSG00000071794.11chr3-148782577148782653148781260148781311148786026148786122-0.153000.000000.00010excludedK562U2AF2
    SEHLTFENSG00000071794.11chr3-148782577148782653148781217148781311148786026148786122-0.065000.000420.01394excludedK562RBM15
    SEHLTFENSG00000071794.11chr3-148782577148782653148781217148781311148786026148786122-0.157000.000000.00000excludedK562AGGF1
    SEHLTFENSG00000071794.11chr3-1487698311487699311487680561487681621487730891487731870.160000.000000.00000includedK562HNRNPC
    A3SSHLTFENSG00000071794.11chr3-148773089148773187148773089148773175148777504148777594-0.081000.000010.00168shorterK562SF3B4
    A3SSHLTFENSG00000071794.11chr3-1487568351487570511487568351487570161487573671487574800.064000.000000.00000longerK562AQR
    A3SSHLTFENSG00000071794.11chr3-1487775041487776611487775041487775941487784291487784540.058000.000150.00122longerK562AQR
    MXEHLTFENSG00000071794.11chr3-148759952148760077148763866148764046148757817148757943148765814148765950-0.051000.000310.003252includedK562AQR
    MXEHLTFENSG00000071794.11chr3-148768018148768162148773089148773187148766649148766788148777504148777594-0.107000.003070.023862includedK562AQR

    *: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
    **: "-log(0)" was displayed as "99999.99999".





    No autoregularoty alternative splicing events between protein HLTF and its RNA.