DEF8

General Information

Gene Name       : DEF8
Gene ID             : ENSG00000140995.16
Essential Gene : No

Functions

Localization

Domains (AlphaFold: DEF8)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878DEF8ENSG00000140995.168.5519.6114.08ENCSR000AEF
HepG2DEF8ENSG00000140995.1696.3633.6965.03ENCSR985KAT
K562DEF8ENSG00000140995.1663.8028.4346.11ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for DEF8 is not avaliable on ENCORE database.



Proteins bound to RNA
  • DEF8 RNA is bound by 27 proteins.  







eCLIP assay for DEF8 is not avaliable on ENCORE database.





27 proteins are bound to DEF8 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr169002391690023983+3'-UTR,CDS,intron-Proximal4.639897.49899HepG2PPIG
chr169003394290034057+3'-UTR3.246293.17522HepG2LSM11
chr169002157490021621+3'-UTR,5'-UTR,CDS,intron-Proximal3.332066.27819HepG2PPIG
chr169003423190034279+3'-UTR3.149113.03634HepG2PABPN1
chr169002544990025490+3'-UTR,CDS,intron-Distal3.393963.93645HepG2PPIG
chr169003321190033292+3'-UTR3.439804.48398HepG2LSM11
chr169002393090024024+3'-UTR,CDS,intron-Proximal3.204283.40321HepG2GRWD1
chr169003244090032497+3'-UTR3.428493.72765HepG2UPF1
chr169002391790023988+3'-UTR,CDS,intron-Proximal3.321005.77413K562DDX24
chr169002400990024074+3'-UTR,CDS,intron-Proximal3.839469.02617HepG2PPIG
chr169002403590024112+3'-UTR,CDS,intron-Proximal3.5167113.86528HepG2PRPF8
chr169003360290033662+3'-UTR3.849513.18535HepG2LSM11
chr169003322190033299+3'-UTR5.105214.99413HepG2EIF3H
chr169002162390021674+3'-UTR,5'-UTR,CDS3.160683.91443HepG2PPIG
chr169001577990015852+5'-UTR,intron-Distal,intron-Proximal3.5655212.64373HepG2EFTUD2
chr169001577290015884+5'-UTR,CDS,intron-Distal,intron-Proximal4.1237510.99589K562CSTF2T
chr169001522090015262+5'-UTR,CDS,intron-Proximal4.378834.59919HepG2AQR
chr169001578090015856+5'-UTR,intron-Distal,intron-Proximal3.865198.80665HepG2FAM120A
chr169001578590015860+5'-UTR,intron-Distal,intron-Proximal3.501677.70675K562AQR
chr169001577890015855+5'-UTR,intron-Distal,intron-Proximal3.354817.53508HepG2BUD13
chr169001566290015857+5'-UTR,intron-Distal,intron-Proximal3.769963.35564K562FUS
chr169002059590020638+5'-UTR,intron-Distal,intron-Proximal4.041956.75344HepG2EFTUD2
chr169001578290015856+5'-UTR,intron-Distal,intron-Proximal3.276274.58795K562EWSR1
chr169001577190015890+5'-UTR,CDS,intron-Distal,intron-Proximal3.330975.85200K562BUD13
chr169001587990015951+5'-UTR,CDS,intron-Distal,intron-Proximal4.3013513.85817HepG2PRPF8
chr169001578590015861+5'-UTR,intron-Distal,intron-Proximal3.035714.57739K562GTF2F1
chr169001570390015874+5'-UTR,intron-Distal,intron-Proximal3.362863.94496K562RBFOX2
chr169001577590015860+5'-UTR,intron-Distal,intron-Proximal4.4314111.47727HepG2PRPF4
chr169001580490015856+5'-UTR,intron-Distal,intron-Proximal4.3871925.74340HepG2PRPF8
chr169001901490019085+5'-UTR,intron-Distal4.100613.96304K562CSTF2T
chr169001580690015877+5'-UTR,CDS,intron-Distal,intron-Proximal6.4122119.07166HepG2AQR
chr169001578390015857+5'-UTR,intron-Distal,intron-Proximal3.606156.24011K562AKAP8L
chr169001578490015853+5'-UTR,intron-Distal,intron-Proximal3.911143.80864K562FAM120A
chr169001578590015859+5'-UTR,intron-Distal,intron-Proximal3.630366.40067K562PRPF8
chr169003087290030926+CDS,intron-Proximal3.760343.38114HepG2GRWD1
chr169002382290023898+CDS,intron-Distal,intron-Proximal4.122233.25678HepG2SF3B4
chr169002841390028466+CDS,intron-Distal,intron-Proximal3.106214.42661HepG2PPIG
chr169002745190027501+CDS,intron-Distal3.662324.68902HepG2PPIG
chr169003052290030585+CDS,intron-Distal,intron-Proximal4.079723.56076K562BUD13
chr169002966590029777+CDS,intron-Distal,intron-Proximal3.502148.68232HepG2SF3B4
chr169002071290020767+CDS,intron-Distal4.141119.85077HepG2PPIG
chr169002838590028459+CDS,intron-Distal,intron-Proximal3.757374.88100K562AQR
chr169002076790020787+CDS,intron-Distal,intron-Proximal4.198996.92541HepG2PPIG
chr169002838890028459+CDS,intron-Distal,intron-Proximal3.473014.25142K562BUD13
chr169002821390028273+CDS,intron-Distal,intron-Proximal3.529165.30777HepG2PPIG
chr169002842090028478+CDS,intron-Distal5.636027.63756K562DDX24
chr169002552290025587+CDS,intron-Distal,intron-Proximal4.395834.16170K562UCHL5
chr169002984890029867+CDS,intron-Distal,intron-Proximal3.527314.83230K562AQR
chr169002980490029899+CDS,intron-Distal,intron-Proximal5.8378614.68744HepG2PPIG
chr169001598090016044+CDS,intron-Distal,intron-Proximal4.774696.08348HepG2CSTF2T
chr169002825890028413+CDS,intron-Distal,intron-Proximal5.3224210.80898HepG2PRPF4
chr169002982190029897+CDS,intron-Distal,intron-Proximal3.0702510.52055HepG2PRPF8
chr169002966290029757+intron-Distal,intron-Proximal4.106656.28719HepG2SF3A3
chr169003028790030440+intron-Distal,intron-Proximal3.7450811.72540HepG2RBFOX2
chr169001613490016188+intron-Distal,intron-Proximal4.677246.38928HepG2NKRF
chr169001551790015599+intron-Distal4.336803.03048HepG2GTF2F1
chr169003051790030573+intron-Distal,intron-Proximal3.269946.11656HepG2PRPF4
chr169001948790019591+intron-Distal5.5495811.38012HepG2QKI
chr169001572990015805+intron-Distal,intron-Proximal5.016896.38747HepG2AQR
chr169001572390015772+intron-Distal,intron-Proximal3.142608.75624HepG2PRPF8
chr169001549390015600+intron-Distal3.183067.41315K562CSTF2T
chr169001549890015624+intron-Distal5.9071611.52233K562GTF2F1
chr169001570790015775+intron-Distal,intron-Proximal3.9322911.54047HepG2PRPF4
chr169003033790030412+intron-Distal,intron-Proximal4.468965.64870K562DDX24
chr169001570690015778+intron-Distal,intron-Proximal3.031763.33035K562EWSR1
chr169001551590015604+intron-Distal5.111528.98213HepG2PRPF4
chr169003030390030411+intron-Distal,intron-Proximal4.053877.73723HepG2GTF2F1
chr169001548990015593+intron-Distal5.2070813.01160K562PRPF8
chr169003029590030400+intron-Distal,intron-Proximal3.647725.14244K562DROSHA
chr169002829190028379+intron-Distal,intron-Proximal4.732516.03362HepG2AQR
chr169003030490030363+intron-Distal,intron-Proximal4.261518.40329HepG2PRPF4
chr169001567290015785+intron-Distal,intron-Proximal4.9698014.02567K562GTF2F1
chr169003035490030444+intron-Distal,intron-Proximal4.348063.53509HepG2HLTF
chr169003036390030386+intron-Distal,intron-Proximal5.5256913.71413HepG2PRPF4
chr169003032490030434+intron-Distal,intron-Proximal4.120924.50422HepG2DROSHA
chr169001548590015614+intron-Distal4.481185.89564K562AKAP8L
chr169001577290015804+intron-Distal,intron-Proximal3.166328.00684HepG2PRPF8
chr169002634190026396+intron-Distal5.3508910.47230HepG2HNRNPM
chr169001570490015769+intron-Distal,intron-Proximal4.610544.70962HepG2GTF2F1
chr169001551890015581+intron-Distal3.659953.39008HepG2AQR
chr169001551290015617+intron-Distal5.8997216.94336HepG2CSTF2T
chr169003046990030562+intron-Distal,intron-Proximal4.138174.14518HepG2GTF2F1
chr169003034790030429+intron-Distal,intron-Proximal3.033407.83416HepG2PRPF8
chr169002046090020545+intron-Distal3.992743.43867K562CSTF2T
chr169003036190030434+intron-Distal,intron-Proximal4.244456.53298K562SF3B4
chr169001548690015605+intron-Distal4.6380819.93742HepG2FAM120A
chr169003032190030431+intron-Distal,intron-Proximal3.758565.84546K562RBFOX2
chr169002750390027568+intron-Distal,intron-Proximal3.916114.98250K562AQR
chr169003031690030413+intron-Distal,intron-Proximal3.196424.68402HepG2CSTF2T
chr169003030890030406+intron-Distal,intron-Proximal3.427717.95421HepG2FAM120A
chr169001568290015771+intron-Distal,intron-Proximal4.199873.96990K562BUD13
chr169001549190015603+intron-Distal4.0599833.15797HepG2PRPF8
chr169001570790015780+intron-Distal,intron-Proximal4.2681113.40790HepG2FAM120A
chr169002853990028644+intron-Distal,intron-Proximal3.500993.68924HepG2PRPF4
chr169002986790029913+intron-Distal,intron-Proximal4.681376.99120K562AQR
chr169001627290016316+intron-Distal3.493754.37279HepG2CSTF2T
chr169001548790015597+intron-Distal5.372536.31097K562FAM120A
chr169001550990015614+intron-Distal3.523126.39220HepG2RBFOX2
chr169003038690030443+intron-Distal,intron-Proximal5.3728811.71790HepG2PRPF4
chr169001553090015622+intron-Distal5.3268816.14488HepG2EFTUD2
chr169001571290015772+intron-Distal,intron-Proximal3.198324.87483K562CSTF2T
chr169003036390030416+intron-Distal,intron-Proximal4.473015.52476K562BUD13
chr169001566790015689+intron-Distal5.356633.93931HepG2EFTUD2
chr169003098990031021+intron-Proximal4.802234.35676HepG2PRPF8
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for DEF8 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for DEF8 is not available on ENCORE database.

  • 107 RBPs can affect the levels of DEF8.  








The Knockdown/knockout RNA-Seq assay for DEF8 is not available on ENCORE database.





107 RBPs can affect the gene expression of DEF8 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
DEF8ENSG00000140995.121764.533301297.220700.443808.322107.38300HepG2ACO1
DEF8ENSG00000140995.122378.360901193.236200.995006.968106.16610HepG2AKAP1
DEF8ENSG00000140995.121782.279501161.654200.617405.782304.30500HepG2AKAP8
DEF8ENSG00000140995.121376.94740987.230700.479903.911802.98480HepG2ASCC1
DEF8ENSG00000140995.122870.893801780.206600.6894020.4074018.85410HepG2AUH
DEF8ENSG00000140995.121333.41770598.425801.1558021.4631020.04020HepG2BOP1
DEF8ENSG00000140995.121235.66240937.960400.397602.878202.08970HepG2CIRBP
DEF8ENSG00000140995.121679.952001296.923800.373206.454005.51520HepG2CKAP4
DEF8ENSG00000140995.12739.43400587.530300.331702.622201.63310HepG2YBX3
DEF8ENSG00000140995.121993.789101077.762200.8874025.4648023.91810HepG2CELF1
DEF8ENSG00000140995.121465.321501158.756200.338505.316904.33470HepG2DAZAP1
DEF8ENSG00000140995.12760.60780588.343600.370403.114701.89210HepG2DDX1
DEF8ENSG00000140995.122456.203601142.875301.1037019.0515017.56650HepG2DDX3X
DEF8ENSG00000140995.122276.81960982.117801.2130019.6642018.21550HepG2DDX6
DEF8ENSG00000140995.12869.81130576.901600.592307.745106.61660HepG2DNAJC21
DEF8ENSG00000140995.121007.49250571.820700.8170018.9066017.35030HepG2DNAJC2
DEF8ENSG00000140995.121729.61170943.772100.8738011.8092010.63760HepG2EIF2S1
DEF8ENSG00000140995.121714.884401042.804200.717507.203306.17170HepG2EIF4A3
DEF8ENSG00000140995.121952.369801015.650100.942709.760308.50710HepG2EIF4B
DEF8ENSG00000140995.121344.115501143.272600.233402.423101.63100HepG2EIF4G1
DEF8ENSG00000140995.122116.889001222.790100.791704.481603.51880HepG2FIP1L1
DEF8ENSG00000140995.121827.880101052.675000.7960010.214508.96720HepG2FXR1
DEF8ENSG00000140995.121712.57280976.232000.810809.670808.46480HepG2G3BP1
DEF8ENSG00000140995.12799.37080622.729100.360201.926901.38630HepG2GPKOW
DEF8ENSG00000140995.121346.63650884.267700.606703.669302.07830HepG2HNRNPA0
DEF8ENSG00000140995.12913.48870582.428600.649202.832602.17880HepG2HNRNPA1
DEF8ENSG00000140995.12941.63310647.848600.539402.168901.54660HepG2HNRNPC
DEF8ENSG00000140995.121395.382501073.274000.378505.038904.10730HepG2HNRNPF
DEF8ENSG00000140995.121693.93730989.173300.7760010.745209.45070HepG2HNRNPK
DEF8ENSG00000140995.121267.890601055.507000.264403.177702.45870HepG2HNRNPL
DEF8ENSG00000140995.121176.90270643.565100.8707020.4366018.90010HepG2HNRNPU
DEF8ENSG00000140995.121417.187501056.870100.423104.730603.80680HepG2IGF2BP1
DEF8ENSG00000140995.121830.48360992.219500.8834012.5634011.24500HepG2IGF2BP2
DEF8ENSG00000140995.121329.66930998.188400.413602.336801.42750HepG2KHSRP
DEF8ENSG00000140995.121437.054401101.285200.383802.265901.52170HepG2LARP4
DEF8ENSG00000140995.121115.21920715.777100.639603.512402.23390HepG2LARP7
DEF8ENSG00000140995.121596.255101053.044800.600005.865904.92110HepG2MAGOH
DEF8ENSG00000140995.121687.890101058.852500.672606.504205.56980HepG2MATR3
DEF8ENSG00000140995.121432.06350989.062300.533903.986403.01980HepG2MSI2
DEF8ENSG00000140995.122394.723501083.724501.1438019.5326017.94920HepG2NCBP2
DEF8ENSG00000140995.121627.594601149.025700.502205.760304.66540HepG2NOL12
DEF8ENSG00000140995.121430.75100954.983200.583103.114802.16990HepG2PABPC1
DEF8ENSG00000140995.121422.88710964.805800.560405.047404.08310HepG2PABPC4
DEF8ENSG00000140995.12750.72770574.007800.387103.053202.28310HepG2PPIL4
DEF8ENSG00000140995.121587.319201065.292300.5752011.1058010.15180HepG2PTBP1
DEF8ENSG00000140995.121384.043401096.874100.335402.899302.29110HepG2PUF60
DEF8ENSG00000140995.121788.244201164.413600.6188017.6726016.44090HepG2PUM1
DEF8ENSG00000140995.121915.326501163.542300.719007.002305.95380HepG2PUM2
DEF8ENSG00000140995.121641.515401321.301200.313004.359203.61820HepG2PUS1
DEF8ENSG00000140995.121598.290901153.595800.470306.462805.56450HepG2QKI
DEF8ENSG00000140995.121530.704601172.651000.384304.029303.01680HepG2RBM15
DEF8ENSG00000140995.122305.118901708.353100.432106.917006.18550HepG2RBM22
DEF8ENSG00000140995.121350.959001047.016000.367603.332802.59800HepG2RBM25
DEF8ENSG00000140995.121384.42460863.169200.681503.466702.34970HepG2RBM27
DEF8ENSG00000140995.121868.162201185.512700.6560014.7920013.72700HepG2NELFE
DEF8ENSG00000140995.121400.363601104.244500.342603.472702.79190HepG2RECQL
DEF8ENSG00000140995.121731.320901156.154800.582403.060302.34750HepG2RPLP0
DEF8ENSG00000140995.12841.60770600.482600.486903.015502.37760HepG2RPS19
DEF8ENSG00000140995.121196.67320795.969200.588102.661201.87520HepG2RPS2
DEF8ENSG00000140995.12863.91740573.120500.592008.971107.91480HepG2SAFB2
DEF8ENSG00000140995.121661.630501174.577500.500403.400902.65070HepG2SF3A3
DEF8ENSG00000140995.121700.116401108.987200.6163013.0523011.91720HepG2SF3B4
DEF8ENSG00000140995.121369.094101051.799600.380306.100905.12300HepG2SLBP
DEF8ENSG00000140995.121125.78230668.351000.7522017.3267015.92860HepG2SMN1
DEF8ENSG00000140995.121109.58530672.593000.722105.845604.41750HepG2SMNDC1
DEF8ENSG00000140995.122329.216201929.511400.271503.848503.28690HepG2SRFBP1
DEF8ENSG00000140995.121487.978301083.043300.458207.555006.58880HepG2SRSF5
DEF8ENSG00000140995.121297.518601054.450600.299203.293202.54290HepG2SRSF7
DEF8ENSG00000140995.121178.70760941.804300.323604.031903.38910HepG2SRSF9
DEF8ENSG00000140995.121487.97700913.589000.703604.577403.12750HepG2STIP1
DEF8ENSG00000140995.121852.222401231.684400.5885014.9481013.68940HepG2SUCLG1
DEF8ENSG00000140995.121288.10050625.327101.0425022.2946021.12770HepG2TIAL1
DEF8ENSG00000140995.121216.38180630.934900.9469024.4511022.98010HepG2TRIM56
DEF8ENSG00000140995.121570.555801071.653900.551307.345005.81180HepG2TUFM
DEF8ENSG00000140995.121888.259101134.364600.735104.359103.29280HepG2UBE2L3
DEF8ENSG00000140995.121209.12930482.476901.3253012.6104011.01670HepG2UCHL5
DEF8ENSG00000140995.121232.555901041.671800.242702.462901.79780HepG2UPF1
DEF8ENSG00000140995.121359.096201070.685000.344003.616102.43510HepG2UTP18
DEF8ENSG00000140995.121470.990101005.691500.5485010.228609.19300HepG2UTP3
DEF8ENSG00000140995.121915.445001145.638000.7414024.7099023.48440HepG2ZNF622
DEF8ENSG00000140995.121417.807301002.178000.500408.081407.18210K562AGGF1
DEF8ENSG00000140995.121476.834701101.232600.423304.076302.83290K562AKAP8
DEF8ENSG00000140995.121438.499501042.809300.464004.651903.79840K562AKAP8L
DEF8ENSG00000140995.121923.751901538.790200.322002.505001.94030K562AQR
DEF8ENSG00000140995.121026.07150738.275000.474803.580602.48290K562BCLAF1
DEF8ENSG00000140995.12766.47510990.04350-0.369303.175301.55120K562CEBPZ
DEF8ENSG00000140995.12500.61500358.384200.482103.283502.42710K562CPSF6
DEF8ENSG00000140995.12767.97400560.091900.455303.267202.10520K562CSTF2
DEF8ENSG00000140995.12842.63400647.147100.380702.679401.38260K562DDX27
DEF8ENSG00000140995.12953.93760723.820300.398203.539302.34110K562DDX3X
DEF8ENSG00000140995.121006.27560619.674600.699307.184105.65430K562EFTUD2
DEF8ENSG00000140995.12901.34800663.350200.442202.534001.54870K562EIF3D
DEF8ENSG00000140995.12522.41810399.234300.387902.744901.95120K562EIF3G
DEF8ENSG00000140995.12947.58230756.238100.325302.349101.59140K562EIF4A3
DEF8ENSG00000140995.12899.19890681.056800.400804.105302.64920K562EIF4B
DEF8ENSG00000140995.12389.92140524.50180-0.427802.327601.30490K562FKBP4
DEF8ENSG00000140995.121036.57490786.460000.398304.435303.69340K562FXR1
DEF8ENSG00000140995.12161.00200317.94160-0.981706.150005.00620K562G3BP2
DEF8ENSG00000140995.12472.93600342.135800.467002.268301.54890K562GPKOW
DEF8ENSG00000140995.122092.286401362.597800.618605.314104.26100K562GRSF1
DEF8ENSG00000140995.12815.14910604.003800.432403.421702.76840K562HNRNPC
DEF8ENSG00000140995.12729.18460539.409400.434803.292202.03820K562HNRNPF
DEF8ENSG00000140995.12941.97580584.835800.687602.796301.76550K562IGF2BP2
DEF8ENSG00000140995.12889.71700614.300700.534305.336704.15790K562MAGOH
DEF8ENSG00000140995.121595.287801239.770600.363603.550302.50120K562MBNL1
DEF8ENSG00000140995.12516.02720333.976600.627605.004203.80690K562METAP2
DEF8ENSG00000140995.121094.72740938.212200.222502.005001.31120K562MTPAP
DEF8ENSG00000140995.121065.11120695.552600.614702.593101.64240K562PABPN1
DEF8ENSG00000140995.12758.67360546.513700.473102.387301.48220K562PCBP2
DEF8ENSG00000140995.121096.42410687.549100.673202.075001.36810K562PPIG
DEF8ENSG00000140995.12824.36670603.018100.451003.032002.24610K562PRPF8
DEF8ENSG00000140995.12742.73660541.561900.455603.526202.48740K562PSIP1
DEF8ENSG00000140995.12830.27170596.856900.476104.529403.70010K562PTBP1
DEF8ENSG00000140995.121749.988101034.197500.7587010.877709.84950K562PUS1
DEF8ENSG00000140995.121499.398401007.655700.573308.921607.88200K562RBM15
DEF8ENSG00000140995.12766.65050572.129500.422102.243101.49060K562RBM22
DEF8ENSG00000140995.12929.79450614.144900.598204.327203.30080K562RPS19
DEF8ENSG00000140995.12579.61440330.680400.809609.579207.93900K562SF3B4
DEF8ENSG00000140995.12705.56670468.436100.590805.086503.57040K562SRFBP1
DEF8ENSG00000140995.12876.05240585.156800.582106.063505.02460K562SRSF1
DEF8ENSG00000140995.12741.33880552.730600.423502.330401.37970K562SRSF5
DEF8ENSG00000140995.12802.73080583.678600.459602.847801.81580K562SUPV3L1
DEF8ENSG00000140995.121059.95890592.134900.8399010.705109.16050K562TARDBP
DEF8ENSG00000140995.12928.73670571.202500.701208.841007.26380K562TIA1
DEF8ENSG00000140995.12801.75380560.713500.515804.280602.87280K562TRA2A
DEF8ENSG00000140995.12749.29910553.424400.437103.047502.04430K562TRIM56
DEF8ENSG00000140995.12807.28210617.838600.385702.347401.41850K562UCHL5
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for DEF8 is not available on ENCORE database.





25 RBPs can affect the splicing of DEF8 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEDEF8ENSG00000140995.12chr16+9001582490015921900152029001522290020650900207840.230000.000270.02992includedHepG2G3BP1
SEDEF8ENSG00000140995.12chr16+900158249001592190015202900152229002065090020784-0.102000.001430.02792excludedK562SRSF1
SEDEF8ENSG00000140995.12chr16+900158249001592190015202900152229002065090020784-0.294000.000000.00000excludedHepG2RBM22
SEDEF8ENSG00000140995.12chr16+900158249001604690015182900152229002065090020784-0.145000.001100.03409excludedK562AKAP8L
SEDEF8ENSG00000140995.12chr16+9001582490015921900152029001522290020650900207840.381000.000010.00258includedHepG2TBRG4
SEDEF8ENSG00000140995.12chr16+9001582490015921900152029001522290020650900207840.231000.000760.06224includedHepG2QKI
SEDEF8ENSG00000140995.12chr16+9001896990019090900158249001592190020650900207840.069000.010880.08685includedK562AQR
SEDEF8ENSG00000140995.12chr16+900158249001592190015202900152229002065090020784-0.369000.000170.03550excludedK562DROSHA
SEDEF8ENSG00000140995.12chr16+900158249001592190015202900152229002065090020784-0.218000.000020.00054excludedK562PUS1
SEDEF8ENSG00000140995.12chr16+9001582490015921900152029001522290020650900207840.218000.000360.02700includedHepG2NCBP2
SEDEF8ENSG00000140995.12chr16+900158249001592190015202900152229002065090020784-0.319000.000160.09822excludedHepG2HLTF
SEDEF8ENSG00000140995.12chr16+900158249001592190015202900152229002065090020784-0.226000.000150.00518excludedHepG2SRSF1
SEDEF8ENSG00000140995.12chr16+9001582490015921900152029001522290020650900207840.260000.000010.00249includedHepG2SSB
SEDEF8ENSG00000140995.12chr16+900206509002078490015104900152229002157690021674-0.111000.001420.06303excludedHepG2PCBP1
SEDEF8ENSG00000140995.12chr16+900158249001604690015182900152229002065090020784-0.150000.002410.06523excludedK562UTP18
SEDEF8ENSG00000140995.12chr16+900158249001592190015202900152229002065090020784-0.164000.002870.06035excludedK562RBM15
SEDEF8ENSG00000140995.12chr16+900206509002078490015104900152229002157690021674-0.269000.000010.00056excludedK562PTBP1
SEDEF8ENSG00000140995.12chr16+900206509002078490015104900152229002157690021674-0.153000.002850.04475excludedK562HNRNPC
A3SSDEF8ENSG00000140995.12chr16+900158249001592190015827900159219001516290015222-0.300000.002750.05940shorterHepG2U2AF2
A3SSDEF8ENSG00000140995.12chr16+9003224190032452900322689003245290030873900309830.093000.001730.01135longerK562AQR
A3SSDEF8ENSG00000140995.12chr16+900239189002406890023948900240689002157690021674-0.073000.005520.03154shorterK562AQR
A3SSDEF8ENSG00000140995.12chr16+900158249001592190015827900159219001516290015222-0.351000.000830.09970shorterHepG2SFPQ
A5SSDEF8ENSG00000140995.12chr16+9001582490016046900158249001592190020650900207840.163000.004100.06148longerK562AQR
A5SSDEF8ENSG00000140995.12chr16+900254219002563990025421900255639002733890027503-0.188000.000020.01408shorterK562MTPAP
A5SSDEF8ENSG00000140995.12chr16+900158249001604690015824900159219002065090020784-0.130000.000000.00053shorterHepG2DDX3X
A5SSDEF8ENSG00000140995.12chr16+900158249001604690015824900159219002065090020784-0.102000.000730.08301shorterHepG2NCBP2
A5SSDEF8ENSG00000140995.12chr16+900158249001604690015824900159219002065090020784-0.122000.000000.00170shorterHepG2AKAP1
A5SSDEF8ENSG00000140995.12chr16+9002542190025639900254219002556390027338900275030.173000.001380.09930longerK562RBM15
A5SSDEF8ENSG00000140995.12chr16+900158249001604690015824900159219002065090020784-0.109000.000380.07316shorterHepG2DDX6
RIDEF8ENSG00000140995.12chr16+9003062890030983900306289003071890030873900309830.160000.000410.00429includedHepG2U2AF2
RIDEF8ENSG00000140995.12chr16+9003062890030983900306289003071890030873900309830.193000.000010.00018includedHepG2U2AF1
RIDEF8ENSG00000140995.12chr16+9003062890030983900306289003071890030873900309830.146000.002080.01311includedK562AQR
RIDEF8ENSG00000140995.12chr16+9003062890030983900306289003071890030873900309830.210000.001370.02374includedK562FXR1
MXEDEF8ENSG00000140995.12chr16+9001582490015921900206509002078490015202900152229002157690021674-0.087000.000810.027312includedK562RBM15
MXEDEF8ENSG00000140995.12chr16+9001582490015921900206969002078490015162900152229002157690021674-0.104000.001690.046902includedK562RBM15
MXEDEF8ENSG00000140995.12chr16+9001582490015921900206509002078490015202900152229002157690021674-0.101000.000020.000742includedK562PUS1
MXEDEF8ENSG00000140995.12chr16+9001582490015921900206969002078490015162900152229002157690021674-0.119000.000150.004522includedK562PUS1
MXEDEF8ENSG00000140995.12chr16+9001582490015921900206509002078490015202900152229002157690021674-0.090000.000680.041912includedK562UTP18
MXEDEF8ENSG00000140995.12chr16+9001582490015921900206969002078490015162900152229002157690021674-0.111000.001100.057472includedK562UTP18
MXEDEF8ENSG00000140995.12chr16+90015824900159219002065090020784900152029001522290021576900216740.084000.001380.047441includedHepG2NCBP2
MXEDEF8ENSG00000140995.12chr16+9001582490015921900206509002078490015202900152229002157690021674-0.080000.001920.066192includedK562AKAP8L

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for DEF8 is not avaliable on ENCORE database.