DDX1

General Information

Gene Name       : DDX1
Gene ID             : ENSG00000079785.14
Essential Gene : Yes

Functions

Localization(RBPImage: DDX1)

Domains (AlphaFold: DDX1)


Antibody Validation

 View validation images for all DDX1 antibodies

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878DDX1ENSG00000079785.1469.3166.4167.86ENCSR000AEF
HepG2DDX1ENSG00000079785.14110.81183.11146.96ENCSR985KAT
K562DDX1ENSG00000079785.14156.72161.03158.88ENCSR000AEO

Assays

3 Released experiments are available on ENCORE database.

Assay TypeExp_NameENCODE IDTarget labelBiosampleStatusLinked AntibodyControlsMethodNote
eCLIPeCLIP: 4231ENCSR293FWYDDX1K562ReleasedENCAB741VROENCSR561QXJ  
knockdown followed by RNA-seq DDX1-BGKLV24-K562ENCSR208GPEDDX1K562ReleasedENCSR667PLJ   shRNAKD% = 77.3,75.0
knockdown followed by RNA-seq DDX1-BGHLV20-HepG2ENCSR070LJODDX1HepG2ReleasedENCSR305XWT   shRNAKD% = 82.0,72.6






  eCLIP  
  RBP    Exp_UID    Cell_Line    ENCODE_ACCESSION    Control_ENCODE_ACCESSION    ENCODE_Antibody_ID    Antibody    Lot_num    Status    Project  
DDX14231K562ENCSR293FWYENCSR561QXJENCAB741VRO703141UnknownReleasedENCODE4


  Antibody Validation  
  GeneName    Antibody_DCC_ID    Product_ID    Lot_ID    Phosphate    HepG2 Primary Validation    K562 Primary Validation    HepG2 Secondary Validation    K562 Secondary Validation  
DDX1ENCAB297EGBGTX10520539904BGHLV20-11, Released, ENCODE3BGKLV24-13, Released, ENCODE3
DDX1ENCAB741VRO703141NoneReleased, ENCODE4BGHLV20-11, Released, ENCODE3BGKLV24-13, Released, ENCODE4


  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
DDX1K562shRNAENCSR208GPEENCSR667PLJDDX1_BGKLV24_13_17604,DDX1_BGKLV24_14_17605non-target_BGKLV24_1_17594,non-target_BGKLV24_2_1759577.3,75.0ReleasedENCODE3
DDX1HepG2shRNAENCSR070LJOENCSR305XWTDDX1-BGHLV20-11_17712,DDX1-BGHLV20-12_17713non-target-BGHLV20-1_17706,non-target-BGHLV20-2_1770782.0,72.6ReleasedENCODE3


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  
    DDX1: Click to RBP Image Database
  • Nuclei
  • Nucleoplasm
  • Mutually Exclusive from Nucleolus
  • Cytoplasm
  • Compartment/Organelle
  • Cytoskeleton
  • Microtubule
  • Cytosolic












    • RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela
    DDX1Product_ID: 703141
    Lot_ID: None
    Source: Thermo Fisher
    Target Name: DDX1-human    		 ThermoFisher_703141_Unknown_DDX1.png<br>Caption: IP-WB analysis of K562 whole cell lysate using the DDX1 specific antibody, 703141. Lanes 1 and 3 are 2.5% of five million whole cell lysate input. Lanes 2 and 4 are 50% of IP enrichment from five million whole cell lysate using normal IgG antibody and the DDX1-specific antibody, 703141. The same antibody was used to detect protein levels via Western blot. This antibody passes preliminary validation and will be further pursued for secondary validation. *NOTE* Protein sizes are taken from Genecards.org and are only estimates based on sequence. Actual protein size may differ based on protein characteristics and electrophoresis method used.
    		 DDX1-K562-703141.png<br>Caption: Western blot following shRNA against DDX1 in K562 whole cell lysate using DDX1 specific antibody. Lane 1 is a ladder, lane 2 is K562 non-targeting control knockdown, lane 3 and 4 are two different shRNA against DDX1. DDX1 protein appears as the green arrow, GAPDH serves as a control and appears in red arrow.
    DDX1Product_ID: GTX105205
    Lot_ID: 39904
    Source: GeneTex
    Target Name: DDX1-human    		 DDX1_Secondary_Western.png<br>Caption: Western blot following shRNA against DDX1 in K562 and HepG2 whole cell lysate using DDX1 specific antibody. Lane 1 is a ladder, lane 2 is K562 non-targeting control knockdown, lane 3 and 4 are two different shRNAs against DDX1. Lanes 5-8 follow the same pattern, but in HepG2. DDX1 protein appears as the green band, Tubulin serves as a control and appears in red.
    		 DDX1_Secondary_Western.png<br>Caption: Western blot following shRNA against DDX1 in K562 and HepG2 whole cell lysate using DDX1 specific antibody. Lane 1 is a ladder, lane 2 is K562 non-targeting control knockdown, lane 3 and 4 are two different shRNAs against DDX1. Lanes 5-8 follow the same pattern, but in HepG2. DDX1 protein appears as the green band, Tubulin serves as a control and appears in red.








    RNA Targets

    • eCLIP assay for DDX1 is not avaliable on ENCORE database.



    Proteins bound to RNA
    • DDX1 RNA is bound by 31 proteins.  







    eCLIP assay for DDX1 is not avaliable on ENCORE database.





    31 proteins are bound to DDX1 RNA:

    Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
    chr21577104315771170+3'-UTR3.8824410.42561K562NOLC1
    chr21577103915771122+3'-UTR6.4715724.15382HepG2SUB1
    chr21577112215771174+3'-UTR7.0869221.85814HepG2SUB1
    chr21577113515771205+3'-UTR3.013719.02046K562PABPC4
    chr21573200615732076+5'-UTR,CDS,intron-Proximal4.076808.73668K562FMR1
    chr21573202215732136+5'-UTR,CDS,intron-Proximal3.8477516.51596HepG2PRPF8
    chr21573201515732073+5'-UTR,CDS3.692686.48534K562FXR2
    chr21573204315732073+5'-UTR,CDS3.109164.14020K562BUD13
    chr21573200715732077+5'-UTR,CDS,intron-Proximal3.201988.70525HepG2NCBP2
    chr21573684115736886+CDS,intron-Proximal3.303574.18806HepG2U2AF2
    chr21573529515735321+CDS,intron-Proximal4.272784.45558HepG2GRWD1
    chr21575735815757416+CDS,intron-Proximal3.025199.12729HepG2U2AF2
    chr21577020815770233+CDS3.849903.86978K562YBX3
    chr21576117415761251+CDS,intron-Proximal3.521536.53375HepG2AQR
    chr21576886415768983+CDS,intron-Proximal3.6581812.86780K562EFTUD2
    chr21575828815758334+CDS,intron-Proximal3.062475.70281HepG2U2AF2
    chr21573565515735677+CDS4.450118.41475HepG2BCLAF1
    chr21577019515770235+CDS,intron-Proximal3.960736.20881HepG2SUB1
    chr21573681415736889+CDS,intron-Proximal3.506438.98695K562SF3B4
    chr21573683815736894+CDS,intron-Proximal3.132266.34474K562EFTUD2
    chr21576876415768805+CDS3.184495.51805K562YBX3
    chr21576118815761229+CDS,intron-Proximal4.076907.76216HepG2G3BP1
    chr21576725315767305+CDS,intron-Proximal5.583698.44604HepG2PRPF8
    chr21576726515767310+CDS,intron-Proximal3.752917.34514K562PRPF8
    chr21577089915770908+CDS,intron-Proximal4.388684.96722HepG2G3BP1
    chr21575833715758390+CDS3.599386.66452K562PUM2
    chr21573975315739832+CDS,intron-Proximal3.806528.55183K562SF3B4
    chr21573564715735678+CDS,intron-Proximal3.312958.23377K562DDX3X
    chr21573561315735641+CDS,intron-Proximal3.950085.96588K562ZNF622
    chr21576980615769843+CDS,intron-Proximal3.649313.44979HepG2PRPF8
    chr21575744515757465+CDS3.110913.99124HepG2PPIG
    chr21573561415735676+CDS3.5400510.14543HepG2PPIG
    chr21576851915768572+CDS,intron-Proximal4.522647.56947K562SF3B4
    chr21573531015735320+CDS3.799455.30777HepG2PPIG
    chr21573748515737520+CDS,intron-Proximal4.031404.95436K562GPKOW
    chr21573752115737570+CDS3.686836.57537HepG2G3BP1
    chr21573207215732093+CDS,intron-Proximal5.153074.65563K562AQR
    chr21573979215739822+CDS,intron-Proximal3.161476.80151HepG2BCLAF1
    chr21573564815735697+CDS,intron-Proximal4.598749.08333HepG2PRPF8
    chr21573561415735643+CDS3.365345.76403K562UCHL5
    chr21574633615746368+CDS3.128186.50801HepG2BCLAF1
    chr21573563515735677+CDS4.370768.51520K562DDX24
    chr21576122515761275+CDS,intron-Proximal3.571636.74060K562PRPF8
    chr21576893415768958+CDS4.520695.12780HepG2G3BP1
    chr21575733615757389+CDS,intron-Proximal3.693166.71722K562SF3B4
    chr21576120315761264+CDS,intron-Proximal4.8925113.40522HepG2PRPF8
    chr21577020115770232+CDS3.902279.50935HepG2BCLAF1
    chr21576862115768668+CDS,intron-Proximal6.004817.02967HepG2PRPF8
    chr21576861015768636+CDS4.403464.25741HepG2G3BP1
    chr21573565615735721+CDS,intron-Proximal4.181138.93479K562GPKOW
    chr21574607415746095+CDS4.559108.47938HepG2BCLAF1
    chr21573567415735761+CDS,intron-Proximal3.082828.60981K562AQR
    chr21574457015744632+CDS4.3693818.33118HepG2BCLAF1
    chr21573684915736900+CDS,intron-Proximal4.713908.40808K562GPKOW
    chr21577017215770235+CDS,intron-Proximal3.3137310.31434HepG2PPIG
    chr21576854615768597+CDS,intron-Proximal3.872208.92089K562BUD13
    chr21577016115770235+CDS,intron-Proximal3.080683.26655HepG2LSM11
    chr21574632915746371+CDS3.272755.71803K562UCHL5
    chr21575737115757434+CDS4.796795.66624K562LIN28B
    chr21573528315735321+CDS,intron-Proximal3.237476.46814K562ZNF622
    chr21573566915735677+CDS3.126903.24162HepG2G3BP1
    chr21573529315735352+CDS,intron-Proximal3.898276.46344HepG2PRPF8
    chr21576852015768592+CDS,intron-Proximal3.379099.88576K562GPKOW
    chr21576114815761196+CDS,intron-Proximal3.116074.77826K562AQR
    chr21574267015742730+CDS,intron-Proximal5.009516.77706K562RPS3
    chr21577019815770235+CDS,intron-Proximal5.238098.66806HepG2G3BP1
    chr21573685815736870+CDS3.381366.20035HepG2BCLAF1
    chr21576046015760519+CDS4.316489.38999HepG2G3BP1
    chr21576366215763695+CDS3.459467.66871HepG2BCLAF1
    chr21577020815770257+CDS,intron-Proximal4.213156.81564HepG2PRPF8
    chr21573682615736895+CDS,intron-Proximal5.8938212.95646HepG2AQR
    chr21573752715737571+CDS3.521319.28980HepG2BCLAF1
    chr21573526715735322+CDS,intron-Proximal3.457166.20918K562BUD13
    chr21574395415743994+CDS3.843545.20093K562DDX24
    chr21573983515739878+CDS,intron-Proximal3.152455.83656K562PRPF8
    chr21575829315758339+CDS,intron-Proximal3.754063.58455K562U2AF2
    chr21576974115769763+CDS3.441924.31813HepG2G3BP1
    chr21573981615739853+CDS,intron-Proximal6.6328714.11848HepG2PRPF8
    chr21574613115746148+CDS3.725084.49347K562UCHL5
    chr21576358715763629+CDS4.2979810.68105HepG2BCLAF1
    chr21574613815746145+CDS3.026884.61799HepG2BCLAF1
    chr21574719315747342+CDS,intron-Distal,intron-Proximal3.458219.04953HepG2KHSRP
    chr21574727915747340+CDS,intron-Proximal4.185137.40091HepG2U2AF2
    chr21576856715768641+CDS,intron-Proximal3.295503.98140K562LIN28B
    chr21573768315737796+intron-Distal,intron-Proximal4.180029.68074HepG2EFTUD2
    chr21574719215747212+intron-Distal,intron-Proximal3.984326.62503K562KHSRP
    chr21576433515764444+intron-Distal3.765503.06411K562KHDRBS1
    chr21576625815766331+intron-Distal4.7036111.12558HepG2QKI
    chr21576056215760627+intron-Distal,intron-Proximal3.743366.21987K562AQR
    chr21573224315732308+intron-Distal5.585695.99517HepG2EFTUD2
    chr21574470215744759+intron-Distal,intron-Proximal3.786064.25479HepG2PCBP2
    chr21574283115742885+intron-Distal,intron-Proximal3.535845.28960K562AQR
    chr21573769615737790+intron-Distal5.0004413.76505K562PRPF8
    chr21573766315737797+intron-Distal,intron-Proximal3.231224.33188HepG2CDC40
    chr21573824915738304+intron-Distal4.118386.17334HepG2U2AF2
    chr21576989615769996+intron-Distal,intron-Proximal4.433436.09994K562KHSRP
    chr21575323015753283+intron-Distal,intron-Proximal3.701344.50744HepG2U2AF2
    chr21573807815738161+intron-Distal3.284616.57673K562KHSRP
    chr21576624015766258+intron-Distal3.770355.32632HepG2QKI
    chr21574401615744069+intron-Proximal4.992114.65563K562AQR
    chr21573569515735736+intron-Proximal3.660704.58287K562PRPF8
    chr21573985315739872+intron-Proximal7.3386310.77812HepG2PRPF8
    chr21576052115760562+intron-Proximal4.319796.77156K562AQR
    chr21573209315732149+intron-Proximal3.975904.41130K562AQR
    chr21576864315768660+intron-Proximal4.321663.49003K562PRPF8
    chr21573569015735736+intron-Proximal3.972875.26108K562SF3B4
    chr21576854515768564+intron-Proximal3.267418.37988HepG2BUD13
    chr21574744715747480+intron-Proximal4.469394.21433K562PRPF8
    chr21573567715735737+intron-Proximal3.793204.97312HepG2EFTUD2
    chr21576726915767363+intron-Proximal5.708598.88118K562AQR
    chr21573567915735721+intron-Proximal4.626765.58015HepG2AQR
    chr21574345115743497+intron-Proximal4.176913.02181K562PRPF8
    chr21573210215732151+intron-Proximal4.709656.40957HepG2EFTUD2
    chr21576851715768545+intron-Proximal3.224555.26569HepG2BUD13
    chr21574721215747249+intron-Proximal5.178458.49499K562KHSRP
    chr21573209915732142+intron-Proximal3.843293.09782K562EFTUD2
    chr21574627315746274+intron-Proximal4.174033.59941K562UCHL5
    ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




    eCLIP assay for DDX1 is not avaliable on ENCORE database.



    Diffrential Expression
    • 2,094 differentially expressed genes after Knockdown/Knockout DDX1 protein.  





    • 104 RBPs can affect the levels of DDX1.  







    2,094 differentially expressed genes after Knockdown/Knockout DDX1 protein :

    Only display 100 entries as example. Please click "View All" button to see all 2,094 entries.     

    Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
    FUCA2ENSG00000001036.92684.049103248.19090-0.275202.490201.39540HepG2DDX1
    CYP51A1ENSG00000001630.111736.983402708.20120-0.6408011.593109.47820HepG2DDX1
    LAP3ENSG00000002549.82104.319901758.439100.259002.774501.61300HepG2DDX1
    CD99ENSG00000002586.131940.936201544.325400.329704.067302.68360HepG2DDX1
    LASP1ENSG00000002834.137845.926906175.634100.345306.116804.46200HepG2DDX1
    TFPIENSG00000003436.109116.542207042.939200.372205.774604.16020HepG2DDX1
    ARF5ENSG00000004059.6842.75810670.115300.330602.670701.53330HepG2DDX1
    AK2ENSG00000004455.122542.217702977.23620-0.227902.489001.39460HepG2DDX1
    CDC27ENSG00000004897.72084.470202754.57620-0.402106.329704.65640HepG2DDX1
    HCCSENSG00000004961.10378.88000282.701900.422402.408801.33030HepG2DDX1
    UPF1ENSG00000005007.81344.111701081.455100.313603.116301.89310HepG2DDX1
    DHX33ENSG00000005100.81010.072401228.03060-0.281902.523201.42060HepG2DDX1
    CROTENSG00000005469.7336.08690166.856101.010109.132707.21950HepG2DDX1
    RHBDD2ENSG00000005486.12447.71130314.836500.507903.332602.06140HepG2DDX1
    GDE1ENSG00000006007.71965.926701638.458800.262802.731901.57960HepG2DDX1
    CX3CL1ENSG00000006210.62288.293901247.421800.8752023.9226021.16920HepG2DDX1
    BAIAP2L1ENSG00000006453.9847.80600675.360500.328002.673801.53560HepG2DDX1
    SPAG9ENSG00000008294.162296.848902963.60020-0.367705.479603.90170HepG2DDX1
    MGST1ENSG00000008394.81287.787001779.43910-0.466507.121805.37910HepG2DDX1
    IL32ENSG00000008517.122063.703001445.136300.513908.847206.96300HepG2DDX1
    CSDE1ENSG00000009307.117636.363209749.89090-0.352506.520104.83300HepG2DDX1
    UBE3CENSG00000009335.131820.309501194.138600.6081011.272809.19380HepG2DDX1
    REV3LENSG00000009413.11897.188801300.38120-0.535507.588005.80310HepG2DDX1
    VTA1ENSG00000009844.111240.287701733.78340-0.483207.384905.61600HepG2DDX1
    MLXIPLENSG00000009950.111755.607301197.996300.551206.109104.45610HepG2DDX1
    NCAPD2ENSG00000010292.82831.972603768.93320-0.412304.996803.47580HepG2DDX1
    LYPLA2ENSG00000011009.61185.99720701.741800.757002.743401.58830HepG2DDX1
    SYT7ENSG00000011347.580.53900156.18600-0.955504.437602.98850HepG2DDX1
    PIK3C2AENSG00000011405.92125.627502606.09770-0.294003.661002.33250HepG2DDX1
    QPCTLENSG00000011478.7215.53140314.37710-0.544603.219301.97440HepG2DDX1
    MAP4K3ENSG00000011566.101955.831602301.88030-0.235002.383201.31240HepG2DDX1
    NR1H4ENSG00000012504.9461.26680629.67540-0.449002.662101.52780HepG2DDX1
    KDM5DENSG00000012817.111520.250701257.386900.273802.679301.53950HepG2DDX1
    UBR7ENSG00000012963.9678.18650534.477300.343502.607801.48450HepG2DDX1
    PSMC4ENSG00000013275.31426.979801129.816000.336803.515502.21230HepG2DDX1
    CLDN11ENSG00000013297.6159.00690232.95300-0.550902.676301.53730HepG2DDX1
    PGM3ENSG00000013375.111465.702702143.91270-0.5487010.066008.08340HepG2DDX1
    DPEP1ENSG00000015413.551.39430106.81380-1.055403.848302.49370HepG2DDX1
    MATR3ENSG00000015479.135733.008107583.60450-0.403608.067806.23990HepG2DDX1
    ATP2C1ENSG00000017260.151171.138601422.57080-0.280602.662801.52820HepG2DDX1
    SLC38A5ENSG00000017483.10669.83240837.75650-0.322702.542601.43500HepG2DDX1
    AGPSENSG00000018510.82445.714502958.88990-0.274802.980901.78300HepG2DDX1
    CD74ENSG00000019582.101920.368701285.394400.5791010.664708.63140HepG2DDX1
    ZRANB1ENSG00000019995.6588.22290761.65540-0.372803.017801.81220HepG2DDX1
    SLC7A9ENSG00000021488.889.9636030.532801.558905.774504.16020HepG2DDX1
    SPASTENSG00000021574.7584.44590802.77320-0.457904.418602.97640HepG2DDX1
    CPS1ENSG00000021826.10976.398401320.17580-0.435205.272603.71650HepG2DDX1
    RNH1ENSG00000023191.12528.28530362.060100.545002.503201.40620HepG2DDX1
    RB1CC1ENSG00000023287.81520.063201870.17470-0.299003.196901.95570HepG2DDX1
    ABCC2ENSG00000023839.66751.895305702.681900.243603.370502.09150HepG2DDX1
    NCAPH2ENSG00000025770.14365.47860262.061500.479802.958201.76540HepG2DDX1
    IFNGR1ENSG00000027697.81376.491902150.57530-0.6437010.785808.74840HepG2DDX1
    TBPL1ENSG00000028839.5147.46450233.02110-0.660103.435302.14130HepG2DDX1
    ARNTL2ENSG00000029153.10213.84870339.42650-0.666504.636703.15810HepG2DDX1
    RABEP1ENSG00000029725.12672.13870884.33110-0.395803.615602.29330HepG2DDX1
    BAK1ENSG00000030110.8409.74240298.308600.457802.880501.69940HepG2DDX1
    CENPQENSG00000031691.6148.59410249.17470-0.745804.398702.96020HepG2DDX1
    CHPF2ENSG00000033100.10595.65830410.776000.536004.780003.27940HepG2DDX1
    UBA6ENSG00000033178.81093.493601334.72520-0.287602.770401.61000HepG2DDX1
    ATP6V0A1ENSG00000033627.101495.529601127.237300.407805.103403.56620HepG2DDX1
    SLC4A7ENSG00000033867.12976.115201223.74800-0.326203.225201.97800HepG2DDX1
    UHRF1ENSG00000034063.9940.28740693.135200.439904.562903.09730HepG2DDX1
    MAP2K3ENSG00000034152.14855.32430579.270200.562106.507504.82130HepG2DDX1
    TMSB10ENSG00000034510.46166.795604462.755500.466503.984302.61340HepG2DDX1
    FAM136AENSG00000035141.31763.526301396.634300.336403.973802.60460HepG2DDX1
    TIMP2ENSG00000035862.81952.323901383.620900.496607.935206.11250HepG2DDX1
    RFC1ENSG00000035928.102191.342302630.69280-0.263602.951501.76010HepG2DDX1
    BOD1L1ENSG00000038219.81178.680901483.95980-0.332303.554602.24300HepG2DDX1
    MAT2BENSG00000038274.12529.86280755.13170-0.511105.170003.62350HepG2DDX1
    VCANENSG00000038427.112327.276103654.01090-0.6508016.2844013.90810HepG2DDX1
    CDH1ENSG00000039068.14969.67970627.514700.627808.719806.85010HepG2DDX1
    PHLPP2ENSG00000040199.14428.08590548.66710-0.358002.390001.31720HepG2DDX1
    PQLC2ENSG00000040487.8163.1250095.837300.767203.221401.97540HepG2DDX1
    DCUN1D1ENSG00000043093.9474.66820674.02360-0.505904.676903.19360HepG2DDX1
    PHF15ENSG00000043143.16340.53440245.796200.470202.708301.56100HepG2DDX1
    CTPS2ENSG00000047230.10424.29780635.01300-0.581705.593103.99880HepG2DDX1
    TPRENSG00000047410.93503.861504461.55560-0.348605.609504.01150HepG2DDX1
    CPENSG00000047457.915416.2681024241.55670-0.6530022.3655019.71760HepG2DDX1
    SCML1ENSG00000047634.103055.644402078.472000.5559011.786909.65420HepG2DDX1
    FAM120AENSG00000048828.121899.435701576.095400.269102.742101.58810HepG2DDX1
    ADAMTS6ENSG00000049192.10181.25700274.26550-0.597503.115801.89300HepG2DDX1
    VAMP3ENSG00000049245.82178.682101788.862400.284303.301102.03940HepG2DDX1
    RCN1ENSG00000049449.4797.306401115.07710-0.483905.841004.21550HepG2DDX1
    NFE2L3ENSG00000050344.8411.10730530.29680-0.367302.471301.38110HepG2DDX1
    MAPK9ENSG00000050748.13658.266601028.65580-0.644009.077007.16870HepG2DDX1
    HERPUD1ENSG00000051108.101859.833601266.314500.554403.801002.45500HepG2DDX1
    PIK3CBENSG00000051382.41239.84140969.364500.354903.798702.45400HepG2DDX1
    FNIP2ENSG00000052795.81304.684301079.518000.273202.557601.44540HepG2DDX1
    MSMO1ENSG00000052802.82316.546203004.64260-0.375202.953501.76150HepG2DDX1
    ENTPD2ENSG00000054179.7252.99450378.85290-0.582504.108002.71580HepG2DDX1
    ARID4BENSG00000054267.16708.21310988.49310-0.481005.517303.93520HepG2DDX1
    PLEKHH1ENSG00000054690.9836.85170671.274800.318002.531601.42530HepG2DDX1
    FAM168AENSG00000054965.6640.664301076.35580-0.7485012.2068010.04440HepG2DDX1
    SZRD1ENSG00000055070.121633.156601314.067900.313502.595401.47480HepG2DDX1
    TAB2ENSG00000055208.131227.510002064.25330-0.7499017.2126014.79170HepG2DDX1
    GINM1ENSG00000055211.8766.58540573.419800.418803.125901.90010HepG2DDX1
    EIF2AK2ENSG00000055332.121296.989001610.91810-0.312703.322002.05360HepG2DDX1
    ZFRENSG00000056097.112373.620902887.89310-0.282903.584702.26860HepG2DDX1
    RC3H2ENSG00000056586.11850.912501170.46250-0.460005.571903.98130HepG2DDX1
    PKP2ENSG00000057294.9583.28070779.39600-0.418203.804902.45760HepG2DDX1
    Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

    *: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
    **: "-log(0)" was displayed as "99999.99999".





    104 RBPs can affect the gene expression of DDX1 :

    Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
    DDX1ENSG00000079785.101724.116902768.43940-0.6832010.291008.40360HepG2AATF
    DDX1ENSG00000079785.102211.946302975.46890-0.427804.753103.99490HepG2BOP1
    DDX1ENSG00000079785.102748.559604630.78550-0.752603.042902.01850HepG2CCAR1
    DDX1ENSG00000079785.102785.087903368.30420-0.274305.282904.41790HepG2CKAP4
    DDX1ENSG00000079785.104064.943905227.58840-0.3629010.091908.81530HepG2DAZAP1
    DDX1ENSG00000079785.10423.897702877.43680-2.76300181.40170177.04630HepG2DDX1
    DDX1ENSG00000079785.102844.490004380.46880-0.622906.480205.56560HepG2DDX6
    DDX1ENSG00000079785.102339.420102821.47180-0.270303.346802.57860HepG2DNAJC21
    DDX1ENSG00000079785.101819.386002796.64630-0.6202021.3778019.71980HepG2DNAJC2
    DDX1ENSG00000079785.103171.356704211.45650-0.409203.661002.98430HepG2EIF2S1
    DDX1ENSG00000079785.103768.182604654.35070-0.304701.904501.37000HepG2EIF4A3
    DDX1ENSG00000079785.105971.754205157.339500.211402.980902.11810HepG2EIF4G1
    DDX1ENSG00000079785.103128.057104940.40070-0.6594010.369608.84180HepG2EIF4G2
    DDX1ENSG00000079785.105313.187006566.01850-0.305405.509304.71030HepG2ETF1
    DDX1ENSG00000079785.102472.217203341.00710-0.434503.242602.41520HepG2FIP1L1
    DDX1ENSG00000079785.102733.436603636.40630-0.411802.468501.41210HepG2FUS
    DDX1ENSG00000079785.103666.889204695.45110-0.356703.018502.29490HepG2FXR1
    DDX1ENSG00000079785.103344.657504356.03170-0.381202.975902.28700HepG2G3BP1
    DDX1ENSG00000079785.101493.410501944.63090-0.380903.067302.12000HepG2GEMIN5
    DDX1ENSG00000079785.102508.147903215.92960-0.358602.681301.67960HepG2GNB2L1
    DDX1ENSG00000079785.102124.545703096.33030-0.543405.425304.54910HepG2GPKOW
    DDX1ENSG00000079785.102612.130103168.46280-0.278602.395801.74630HepG2HNRNPC
    DDX1ENSG00000079785.102700.679303678.46270-0.445809.872608.62410HepG2HNRNPF
    DDX1ENSG00000079785.104061.122704761.93190-0.229704.595203.74370HepG2HNRNPL
    DDX1ENSG00000079785.101850.365602954.89780-0.675309.181308.10870HepG2HNRNPLL
    DDX1ENSG00000079785.102776.513203147.51270-0.180902.089601.55480HepG2HNRNPU
    DDX1ENSG00000079785.102606.726303622.23780-0.474607.376106.24640HepG2IGF2BP1
    DDX1ENSG00000079785.102637.071503215.07490-0.285906.253605.19490HepG2ILF2
    DDX1ENSG00000079785.102741.242903079.72500-0.168002.278901.35180HepG2KIF1C
    DDX1ENSG00000079785.103622.447804697.08770-0.374803.120002.42420HepG2MAGOH
    DDX1ENSG00000079785.102295.627103013.92000-0.392802.221101.35890HepG2MTPAP
    DDX1ENSG00000079785.101763.581502270.97620-0.364803.395202.04670HepG2NAA15
    DDX1ENSG00000079785.103606.364205183.66600-0.5234010.719409.25160HepG2NOL12
    DDX1ENSG00000079785.102989.252304306.07970-0.526605.484704.47880HepG2PABPC4
    DDX1ENSG00000079785.102501.032903115.46160-0.316905.107404.00310HepG2PARN
    DDX1ENSG00000079785.103683.548304290.64000-0.220103.028602.39800HepG2PCBP1
    DDX1ENSG00000079785.102141.718402807.32460-0.390406.093605.03200HepG2PPIL4
    DDX1ENSG00000079785.101916.425702730.84480-0.510904.664003.64580HepG2PRPF8
    DDX1ENSG00000079785.103489.957204365.98340-0.323105.553204.83350HepG2PTBP1
    DDX1ENSG00000079785.102784.250204948.26360-0.8296018.9261017.55370HepG2PUF60
    DDX1ENSG00000079785.102919.562503431.59190-0.233103.616702.93200HepG2PUS1
    DDX1ENSG00000079785.104022.781404728.26160-0.233102.574501.96780HepG2QKI
    DDX1ENSG00000079785.104217.946305487.96480-0.379706.947706.21480HepG2RBM22
    DDX1ENSG00000079785.103864.246404858.83990-0.330406.259105.50080HepG2NELFE
    DDX1ENSG00000079785.103498.722904525.49480-0.371207.822106.86390HepG2RECQL
    DDX1ENSG00000079785.102872.400203962.57350-0.464205.833404.89390HepG2RPLP0
    DDX1ENSG00000079785.101715.414902125.19140-0.309002.824602.20430HepG2RPS19
    DDX1ENSG00000079785.102134.333602701.43550-0.339902.003801.32450HepG2RRP9
    DDX1ENSG00000079785.101776.989402802.98180-0.6575021.8127020.25030HepG2SAFB2
    DDX1ENSG00000079785.102223.524603490.11930-0.650405.463004.49700HepG2SF3A3
    DDX1ENSG00000079785.103211.802204545.37880-0.5010013.4299012.28130HepG2SF3B4
    DDX1ENSG00000079785.103886.117804744.61490-0.288006.467405.46670HepG2SLBP
    DDX1ENSG00000079785.102802.032003268.72100-0.222303.937503.19250HepG2SMN1
    DDX1ENSG00000079785.102485.954403387.29190-0.446302.936001.94800HepG2SMNDC1
    DDX1ENSG00000079785.105587.712806198.43350-0.149602.028301.57870HepG2SRFBP1
    DDX1ENSG00000079785.105867.108604744.462200.306306.570005.91620HepG2SRSF1
    DDX1ENSG00000079785.102718.704903613.96070-0.410708.684407.56850HepG2SRSF7
    DDX1ENSG00000079785.103261.957403859.93370-0.242803.854103.22460HepG2SRSF9
    DDX1ENSG00000079785.102704.831303523.38260-0.381402.509201.86150HepG2SUPV3L1
    DDX1ENSG00000079785.103557.112504264.70400-0.261703.427202.81370HepG2TAF15
    DDX1ENSG00000079785.102109.263902880.48450-0.449604.930704.00260HepG2TARDBP
    DDX1ENSG00000079785.103148.783903918.47360-0.315503.470302.53820HepG2TIA1
    DDX1ENSG00000079785.101160.387503058.28570-1.3981053.8189052.13910HepG2TIAL1
    DDX1ENSG00000079785.102210.589103085.74370-0.4812011.5293010.49430HepG2TRIM56
    DDX1ENSG00000079785.102316.893204045.02820-0.804002.322701.42840HepG2U2AF2
    DDX1ENSG00000079785.102225.838402676.44930-0.266004.407903.59080HepG2ZC3H8
    DDX1ENSG00000079785.102186.766003404.12900-0.6385025.9611024.71560HepG2ZNF622
    DDX1ENSG00000079785.106902.333908661.97410-0.327603.154401.83360K562ABCF1
    DDX1ENSG00000079785.103302.648605109.83860-0.6297021.5426020.06990K562AGGF1
    DDX1ENSG00000079785.105507.5546010175.50160-0.8856017.9287016.60200K562AQR
    DDX1ENSG00000079785.104659.680905720.45620-0.295906.032004.59410K562BCLAF1
    DDX1ENSG00000079785.103311.541704487.90690-0.438503.770202.75050K562BOP1
    DDX1ENSG00000079785.101401.417602034.11580-0.537505.975404.27140K562CCAR1
    DDX1ENSG00000079785.106482.238307526.38430-0.215502.799601.68890K562CPEB4
    DDX1ENSG00000079785.103306.204504772.07830-0.529406.331305.14560K562CPSF6
    DDX1ENSG00000079785.103575.136304339.81900-0.279603.689402.44460K562CSTF2
    DDX1ENSG00000079785.10236.410902143.20270-3.1804066.4599062.11280K562DDX1
    DDX1ENSG00000079785.103239.168204056.78150-0.324703.625402.41480K562DDX3X
    DDX1ENSG00000079785.1010802.538807788.281800.4719013.7601012.41630K562DDX47
    DDX1ENSG00000079785.103499.500705123.79580-0.550105.755304.40890K562EFTUD2
    DDX1ENSG00000079785.105191.442508205.12900-0.6604021.2478019.53500K562EIF2S2
    DDX1ENSG00000079785.106398.969005028.826000.347504.769603.74000K562EIF3G
    DDX1ENSG00000079785.103179.068604238.24080-0.414904.897703.80150K562EIF4A3
    DDX1ENSG00000079785.103463.709904855.19450-0.487205.982304.71640K562FMR1
    DDX1ENSG00000079785.103246.563404115.09280-0.342002.799601.87960K562FTO
    DDX1ENSG00000079785.105747.861604407.575900.382907.450106.52130K562FXR1
    DDX1ENSG00000079785.106586.718504863.639200.437403.167302.40250K562G3BP2
    DDX1ENSG00000079785.103744.656705136.86260-0.456104.361502.53820K562GEMIN5
    DDX1ENSG00000079785.102981.884204556.27690-0.611608.451107.05380K562GPKOW
    DDX1ENSG00000079785.107370.7160010934.56060-0.5690010.601609.09440K562GRSF1
    DDX1ENSG00000079785.102902.545104185.22960-0.528004.783004.01870K562HNRNPC
    DDX1ENSG00000079785.102773.678503736.74400-0.430002.908401.73680K562HNRNPF
    DDX1ENSG00000079785.107647.064805889.272600.376703.376601.99520K562HNRNPK
    DDX1ENSG00000079785.105891.176707038.40020-0.256702.506601.50510K562HNRNPL
    DDX1ENSG00000079785.102789.725103890.18680-0.479703.586402.50940K562KRR1
    DDX1ENSG00000079785.102939.533403730.36050-0.343702.958001.36900K562LSM11
    DDX1ENSG00000079785.105268.127106196.67280-0.234202.044501.31730K562MAGOH
    DDX1ENSG00000079785.103193.373304447.38550-0.477905.751304.45940K562METAP2
    DDX1ENSG00000079785.104750.591205729.24480-0.270205.158304.07730K562MTPAP
    DDX1ENSG00000079785.105162.811806365.86910-0.3022010.131708.82580K562NSUN2
    DDX1ENSG00000079785.103740.861504931.99800-0.398803.380802.46050K562PCBP3
    DDX1ENSG00000079785.103047.281403783.13180-0.312103.454502.55390K562POLR2G
    DDX1ENSG00000079785.102413.935103752.31000-0.636406.009504.59830K562PSIP1
    DDX1ENSG00000079785.109109.3481012910.99690-0.503206.788905.51000K562PUF60
    DDX1ENSG00000079785.1010417.6349013455.57600-0.369205.933404.50940K562PUM2
    DDX1ENSG00000079785.104758.341305773.58120-0.279002.429201.64440K562RBM22
    DDX1ENSG00000079785.102475.104203422.59680-0.467604.482503.21700K562RCC2
    DDX1ENSG00000079785.103015.998906281.24490-1.0584049.5033046.73980K562SF3A3
    DDX1ENSG00000079785.102764.376104332.75670-0.648307.702306.03260K562SF3B1
    DDX1ENSG00000079785.103437.366705060.91690-0.558104.272803.20510K562SF3B4
    DDX1ENSG00000079785.102130.459803244.62350-0.606904.015302.70700K562SRFBP1
    DDX1ENSG00000079785.105268.957806435.24910-0.288507.108805.68360K562SRPK2
    DDX1ENSG00000079785.102238.778002852.61680-0.349602.286801.34680K562SRSF4
    DDX1ENSG00000079785.104331.341405573.39330-0.363703.708502.46000K562SRSF5
    DDX1ENSG00000079785.104148.249304965.00820-0.259303.546302.21040K562SRSF7
    DDX1ENSG00000079785.103285.287404828.62460-0.555604.551303.22140K562SUPV3L1
    DDX1ENSG00000079785.105019.126103794.412300.403506.135904.90500K562SYNCRIP
    DDX1ENSG00000079785.103990.464805973.34140-0.582007.910306.63700K562TARDBP
    DDX1ENSG00000079785.104404.363105761.87090-0.387605.388804.18880K562TIA1
    DDX1ENSG00000079785.101931.851003609.20380-0.9017010.558508.63160K562TIAL1
    DDX1ENSG00000079785.104665.863105653.28490-0.276902.457001.44070K562TRA2A
    DDX1ENSG00000079785.102421.280303833.30810-0.662807.190805.51180K562TRIM56
    DDX1ENSG00000079785.103992.428705109.96540-0.356002.724101.71490K562UCHL5
    DDX1ENSG00000079785.105365.962906749.85300-0.331007.632806.51270K562UPF1
    DDX1ENSG00000079785.104497.022805775.65720-0.361004.564503.42680K562WDR3
    DDX1ENSG00000079785.107008.826906005.868100.222704.127503.10880K562WDR43
    DDX1ENSG00000079785.104094.383105202.52270-0.345602.817601.59860K562XRN2
    DDX1ENSG00000079785.108545.9722011463.92110-0.423805.648204.34270K562ZC3H8
    Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

    *: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
    **: "-log(0)" was displayed as "99999.99999".






    The Knockdown/knockout RNA-Seq assay for DDX1 is not available on ENCORE database.





    12 RBPs can affect the splicing of DDX1 :

    Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
    SEDDX1ENSG00000079785.10chr2+157687611576883415768568157686411576972515769821-0.076000.000030.00244excludedK562PRPF8
    SEDDX1ENSG00000079785.10chr2+157533471575340815747298157474371575736715757466-0.088000.000010.00149excludedHepG2PRPF8
    SEDDX1ENSG00000079785.10chr2+157533471575340815747298157474371575736715757466-0.071000.000000.00000excludedK562AQR
    SEDDX1ENSG00000079785.10chr2+157688681576896315768568157686411576972515769821-0.092000.000000.00000excludedK562AQR
    SEDDX1ENSG00000079785.10chr2+157533471575340815747298157474371575736715757466-0.057000.000130.00999excludedHepG2PTBP1
    SEDDX1ENSG00000079785.10chr2+157685681576864115767177157672691576972515769821-0.063000.001590.03285excludedK562U2AF1
    SEDDX1ENSG00000079785.10chr2+157689201576896315768568157686411576972515769821-0.097000.000000.00000excludedHepG2SF3A3
    SEDDX1ENSG00000079785.10chr2+157533471575340815747298157474371575736715757466-0.093000.000250.00995excludedHepG2SF3A3
    SEDDX1ENSG00000079785.10chr2+157689201576896315767177157672691576972515769821-0.082000.000000.00000excludedK562TARDBP
    SEDDX1ENSG00000079785.10chr2+157685681576864115767177157672691576972515769821-0.092000.000560.02568excludedK562SF3B1
    A3SSDDX1ENSG00000079785.10chr2+1575733415757466157573671575746615753347157534080.069000.000000.00000longerK562AQR
    RIDDX1ENSG00000079785.10chr2+1576856815768812157685681576864115768761157688120.062000.000050.00117includedHepG2SF3A3
    MXEDDX1ENSG00000079785.10chr2+15768568157686411576892015768963157671771576726915769725157698210.074000.000650.013641includedK562DROSHA
    MXEDDX1ENSG00000079785.10chr2+15760331157605201576118815761240157583041575839415763559157637060.069000.003410.042281includedK562DROSHA
    MXEDDX1ENSG00000079785.10chr2+15747298157474371575334715753408157462731574638815757367157574660.095000.001040.041371includedK562LIN28B
    MXEDDX1ENSG00000079785.10chr2+15747243157474371575334715753408157462731574638815757367157574660.118000.000000.000001includedK562AQR
    MXEDDX1ENSG00000079785.10chr2+15768568157686411576892015768963157671771576726915769725157698210.068000.017430.098591includedK562AQR
    MXEDDX1ENSG00000079785.10chr2+15760331157605201576355915763706157583041575839415767177157672690.086000.003750.028241includedK562AQR
    MXEDDX1ENSG00000079785.10chr2+15735613157356771573685715736887157317691573207315737498157375950.059000.000130.005391includedK562TARDBP
    MXEDDX1ENSG00000079785.10chr2+15747298157474371575334715753408157462731574638815757367157574660.114000.000040.005691includedK562PHF6
    MXEDDX1ENSG00000079785.10chr2+15768568157686411576876115768834157671771576726915768920157689630.103000.001950.049261includedK562SBDS
    MXEDDX1ENSG00000079785.10chr2+15768568157686411576892015768963157671771576726915769725157698210.067000.003170.047741includedK562HNRNPUL1

    *: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
    **: "-log(0)" was displayed as "99999.99999".





    The Knockdown/knockout RNA-Seq assay for DDX1 is not avaliable on ENCORE database.