CPS1

General Information

Gene Name       : CPS1
Gene ID             : ENSG00000021826.15
Essential Gene : No

Functions

Localization

Domains (AlphaFold: CPS1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878CPS1ENSG00000021826.150.370.430.40ENCSR000AEF
HepG2CPS1ENSG00000021826.1526.5238.5532.53ENCSR985KAT
K562CPS1ENSG00000021826.156.306.266.28ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for CPS1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • CPS1 RNA is bound by 7 proteins.  







eCLIP assay for CPS1 is not avaliable on ENCORE database.





7 proteins are bound to CPS1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr2211460220211460298+5'-UTR,CDS3.715074.46864HepG2BCLAF1
chr2211469828211469925+CDS4.485004.96722HepG2G3BP1
chr2211464236211464285+CDS4.261623.45943HepG2BCLAF1
chr2211455524211455631+CDS,intron-Proximal4.173846.22576HepG2BCLAF1
chr2211476876211477004+CDS3.393143.77614HepG2G3BP1
chr2211471452211471499+CDS,intron-Proximal5.136477.86385HepG2LIN28B
chr2211465277211465363+CDS,intron-Proximal3.669116.39464HepG2BCLAF1
chr2211507300211507387+CDS3.779063.48848HepG2FXR2
chr2211469941211469971+CDS,intron-Proximal4.907916.96848HepG2LIN28B
chr2211421547211421584+CDS,intron-Proximal4.526884.70478HepG2BCLAF1
chr2211464108211464202+CDS4.277483.61890HepG2G3BP1
chr2211502464211502552+CDS4.008153.11149HepG2G3BP1
chr2211343657211343756+intron-Distal5.9348512.71401HepG2PCBP2
chr2211416144211416243+intron-Distal4.406004.05848HepG2QKI
chr2211360662211360755+intron-Distal4.738926.17200HepG2PCBP2
chr2211404964211405024+intron-Distal4.291623.35169HepG2U2AF2
chr2211342708211342837+intron-Distal3.757805.09669HepG2QKI
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for CPS1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for CPS1 is not available on ENCORE database.

  • 120 RBPs can affect the levels of CPS1.  








The Knockdown/knockout RNA-Seq assay for CPS1 is not available on ENCORE database.





120 RBPs can affect the gene expression of CPS1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
CPS1ENSG00000021826.102256.604701573.717300.519904.900303.68120HepG2ABCF1
CPS1ENSG00000021826.101439.096802212.93980-0.620804.413103.76280HepG2AKAP1
CPS1ENSG00000021826.10632.356701017.07940-0.685606.338405.04070HepG2BCLAF1
CPS1ENSG00000021826.10811.005901270.55560-0.647707.562606.63280HepG2BOP1
CPS1ENSG00000021826.101378.321501952.92700-0.502703.568902.44760HepG2CCAR1
CPS1ENSG00000021826.101378.70770805.328300.775603.867002.95660HepG2CNOT7
CPS1ENSG00000021826.10851.321901296.05100-0.606307.350305.63700HepG2CPSF7
CPS1ENSG00000021826.10960.627301318.30610-0.456605.991204.49480HepG2YBX3
CPS1ENSG00000021826.101123.76290723.005100.636206.830005.25460HepG2CSTF2
CPS1ENSG00000021826.10897.782501633.82290-0.8638020.8601019.42830HepG2CELF1
CPS1ENSG00000021826.101625.258001351.815300.265703.515502.58930HepG2DDX19B
CPS1ENSG00000021826.10976.398401320.17580-0.435205.272603.71650HepG2DDX1
CPS1ENSG00000021826.101013.899501270.05580-0.325002.503901.85630HepG2DDX21
CPS1ENSG00000021826.101745.670401242.716100.490206.070704.72300HepG2DDX24
CPS1ENSG00000021826.101480.207101076.817700.458903.012901.66950HepG2DDX27
CPS1ENSG00000021826.10517.63180819.37900-0.662606.678704.74030HepG2DDX47
CPS1ENSG00000021826.10607.792301150.87300-0.9211010.049908.68770HepG2DDX55
CPS1ENSG00000021826.10941.175201820.71210-0.952008.484307.45870HepG2DDX6
CPS1ENSG00000021826.101654.771401398.426000.242702.543001.89030HepG2DKC1
CPS1ENSG00000021826.101047.637201294.52070-0.305303.070002.33370HepG2DNAJC21
CPS1ENSG00000021826.101038.212001283.02740-0.305503.972203.21850HepG2DNAJC2
CPS1ENSG00000021826.10722.613901750.70840-1.2766012.0854010.90000HepG2EIF2S1
CPS1ENSG00000021826.10696.404601003.75570-0.527403.844502.78970HepG2EIF3D
CPS1ENSG00000021826.101219.553301883.55240-0.627104.415003.55710HepG2EIF4B
CPS1ENSG00000021826.102176.283501733.132600.328405.028503.95560HepG2EIF4G1
CPS1ENSG00000021826.101897.440901363.275400.476904.952003.52880HepG2ESF1
CPS1ENSG00000021826.102237.073002558.47720-0.193702.119501.57880HepG2ETF1
CPS1ENSG00000021826.101845.074901428.246000.369303.699602.73470HepG2EWSR1
CPS1ENSG00000021826.10798.980001210.24910-0.599107.238705.55190HepG2FASTKD2
CPS1ENSG00000021826.10774.984501589.08860-1.0360013.0230011.53530HepG2FIP1L1
CPS1ENSG00000021826.101515.859501951.66650-0.364602.152601.53870HepG2FXR1
CPS1ENSG00000021826.101272.63470893.699400.509904.476203.32720HepG2GEMIN5
CPS1ENSG00000021826.10938.022901391.60600-0.569105.124903.73420HepG2GNB2L1
CPS1ENSG00000021826.10622.439501322.30520-1.0870013.4853012.17330HepG2GPKOW
CPS1ENSG00000021826.101139.629601395.44080-0.292203.338402.27090HepG2HDGF
CPS1ENSG00000021826.10290.17170680.48950-1.2297012.180709.27040HepG2HNRNPA0
CPS1ENSG00000021826.101580.949601306.921900.274501.936401.38510HepG2HNRNPA1
CPS1ENSG00000021826.101089.436201614.44460-0.5675010.170308.58880HepG2HNRNPA2B1
CPS1ENSG00000021826.10416.80900664.55960-0.673004.733802.88470HepG2HNRNPAB
CPS1ENSG00000021826.101057.359001453.68830-0.459304.458003.59280HepG2HNRNPC
CPS1ENSG00000021826.101121.433301600.08290-0.5128010.684309.43800HepG2HNRNPL
CPS1ENSG00000021826.10657.936401261.89660-0.9396012.7863011.56310HepG2HNRNPLL
CPS1ENSG00000021826.10807.127801096.43570-0.442004.132102.99020HepG2HNRNPM
CPS1ENSG00000021826.101227.385701840.72690-0.584703.671802.90300HepG2IGF2BP2
CPS1ENSG00000021826.10508.00080766.86440-0.594104.056102.56170HepG2KHDRBS1
CPS1ENSG00000021826.101474.939202061.90320-0.483303.432402.50540HepG2LARP4
CPS1ENSG00000021826.101029.479301363.28880-0.405203.480202.20810HepG2LARP7
CPS1ENSG00000021826.101223.860501952.34520-0.673805.368504.46240HepG2MAGOH
CPS1ENSG00000021826.101268.114701963.37070-0.630604.795303.98200HepG2MATR3
CPS1ENSG00000021826.101148.383702009.69920-0.807406.384705.43920HepG2NCBP2
CPS1ENSG00000021826.101014.079901741.85230-0.7805012.9157011.32470HepG2NOL12
CPS1ENSG00000021826.10721.491201056.83440-0.550702.657601.58760HepG2NONO
CPS1ENSG00000021826.10216.21400735.91370-1.7671018.2684015.97490HepG2PABPC1
CPS1ENSG00000021826.101357.104801790.13600-0.399502.255801.59880HepG2PABPC4
CPS1ENSG00000021826.101200.568901429.41670-0.251702.559801.74220HepG2PARN
CPS1ENSG00000021826.101132.272101772.11640-0.6463014.8275013.60310HepG2PCBP1
CPS1ENSG00000021826.10928.570901466.37450-0.659204.700103.37370HepG2PCBP2
CPS1ENSG00000021826.10346.19500722.09160-1.060608.316105.81300HepG2PNPT1
CPS1ENSG00000021826.10845.793001180.16120-0.480603.326201.40180HepG2PPIG
CPS1ENSG00000021826.101078.065601288.00660-0.256702.297001.61830HepG2PPIL4
CPS1ENSG00000021826.102178.116901417.265300.619908.815607.54550HepG2PRPF4
CPS1ENSG00000021826.102680.082101541.565600.797806.756304.93110HepG2PRPF6
CPS1ENSG00000021826.101540.005801803.17690-0.227602.589202.05700HepG2PTBP1
CPS1ENSG00000021826.101100.511001765.18060-0.6816019.1996017.92220HepG2PUM1
CPS1ENSG00000021826.101076.366201763.85940-0.7126012.5670011.19890HepG2PUM2
CPS1ENSG00000021826.101277.170501952.92300-0.6127010.973309.84860HepG2QKI
CPS1ENSG00000021826.10632.605201415.21880-1.161609.833708.55910HepG2RAVER1
CPS1ENSG00000021826.10933.361201772.38880-0.9252018.5712016.92900HepG2RBM25
CPS1ENSG00000021826.10930.804801334.91170-0.520204.073302.78190HepG2RCC2
CPS1ENSG00000021826.101222.530801498.16620-0.293302.125301.51690HepG2RPLP0
CPS1ENSG00000021826.10649.72240976.75270-0.588206.494405.59620HepG2RPS19
CPS1ENSG00000021826.101081.467701516.12710-0.487404.440903.43930HepG2RPS2
CPS1ENSG00000021826.10607.21610878.18670-0.532303.707502.81470HepG2RRP9
CPS1ENSG00000021826.10723.52260980.23770-0.438103.223702.20560HepG2SERBP1
CPS1ENSG00000021826.10929.261101599.47390-0.783407.684906.52220HepG2SF3A3
CPS1ENSG00000021826.101175.664301877.37180-0.6752016.0442014.79960HepG2SF3B4
CPS1ENSG00000021826.101018.695601499.74680-0.5580012.8174011.59090HepG2SMN1
CPS1ENSG00000021826.10729.176101376.75570-0.916902.884701.53940HepG2SNRNP200
CPS1ENSG00000021826.10953.630801389.78010-0.543403.102602.27510HepG2SNRNP70
CPS1ENSG00000021826.102972.698202415.230200.299505.245004.61550HepG2SRFBP1
CPS1ENSG00000021826.102459.949101959.556700.328005.156704.56260HepG2SRSF1
CPS1ENSG00000021826.10992.852701343.91890-0.436802.623801.65230HepG2SRSF3
CPS1ENSG00000021826.101170.910601594.19250-0.445207.787606.94640HepG2SRSF9
CPS1ENSG00000021826.10340.08310702.87360-1.0474010.363208.09210HepG2STIP1
CPS1ENSG00000021826.10953.854401322.51950-0.471402.558201.40400HepG2SUB1
CPS1ENSG00000021826.10500.917601073.07340-1.0991020.1207017.84950HepG2SUPT6H
CPS1ENSG00000021826.10791.313701145.66660-0.533904.043803.24980HepG2SUPV3L1
CPS1ENSG00000021826.101892.416701189.145400.670203.093901.96870HepG2TBRG4
CPS1ENSG00000021826.101139.038101618.42370-0.506806.539005.25930HepG2TIA1
CPS1ENSG00000021826.10870.136401403.27000-0.6895011.4502010.55590HepG2TIAL1
CPS1ENSG00000021826.10988.238801420.81020-0.523803.220401.63600HepG2TRA2A
CPS1ENSG00000021826.101200.917701415.73100-0.237402.394501.86230HepG2TRIM56
CPS1ENSG00000021826.101271.279101624.56300-0.353803.218302.26840HepG2TUFM
CPS1ENSG00000021826.10373.487601359.39160-1.8638043.7706041.20720HepG2U2AF1
CPS1ENSG00000021826.10903.070601603.28280-0.828102.306001.41600HepG2U2AF2
CPS1ENSG00000021826.101092.258701719.62930-0.654806.415505.10850HepG2UBE2L3
CPS1ENSG00000021826.10469.90200676.77380-0.526303.799102.91030HepG2UCHL5
CPS1ENSG00000021826.101658.491001418.491800.225402.458901.79420HepG2UPF1
CPS1ENSG00000021826.10702.264101049.05390-0.579003.415702.29390HepG2UPF2
CPS1ENSG00000021826.101200.006601457.98810-0.280902.961301.88260HepG2UTP18
CPS1ENSG00000021826.10938.458601369.49340-0.545309.327108.33410HepG2UTP3
CPS1ENSG00000021826.10981.199801391.42550-0.503903.147001.79540HepG2XRCC5
CPS1ENSG00000021826.101168.604601398.66650-0.259303.072002.37240HepG2ZC3H8
CPS1ENSG00000021826.10775.207101560.06510-1.0090037.0480035.64140HepG2ZNF622
CPS1ENSG00000021826.10122.81240220.49900-0.844304.347202.82970K562AARS
CPS1ENSG00000021826.10338.17970471.65630-0.479903.110402.41690K562AKAP8L
CPS1ENSG00000021826.10237.19570485.06930-1.032107.687006.78980K562AQR
CPS1ENSG00000021826.10400.93660294.716400.443902.804601.48430K562BCCIP
CPS1ENSG00000021826.10195.09220284.75160-0.545502.505501.67720K562BOP1
CPS1ENSG00000021826.10109.10640176.08780-0.690602.804301.74150K562CCAR1
CPS1ENSG00000021826.10295.91800440.40420-0.573602.382101.40940K562CNOT7
CPS1ENSG00000021826.10191.22280302.76070-0.662903.930902.99620K562CPSF6
CPS1ENSG00000021826.10544.76600773.92150-0.506604.289803.06640K562CELF1
CPS1ENSG00000021826.10294.78910474.61920-0.687105.165904.31380K562DDX47
CPS1ENSG00000021826.10161.00600229.50000-0.511402.279801.53220K562EIF4A3
CPS1ENSG00000021826.10160.31740328.22220-1.033708.231006.68370K562FIP1L1
CPS1ENSG00000021826.10159.67110238.66900-0.579903.022802.39390K562FXR1
CPS1ENSG00000021826.10158.33960289.05240-0.868305.639604.50950K562GPKOW
CPS1ENSG00000021826.10342.30380478.84480-0.484302.979302.19610K562GRSF1
CPS1ENSG00000021826.10154.84220269.96960-0.802004.198603.03510K562HNRNPM
CPS1ENSG00000021826.10213.33540366.77740-0.781806.390605.08840K562MAGOH
CPS1ENSG00000021826.10161.88830366.01170-1.1769012.6765010.57460K562MATR3
CPS1ENSG00000021826.10156.54020237.76010-0.603002.483501.77230K562PRPF8
CPS1ENSG00000021826.10226.77710356.35780-0.652104.847603.99170K562PTBP1
CPS1ENSG00000021826.10227.78030341.62690-0.584803.608602.63780K562RBM22
CPS1ENSG00000021826.10256.67820359.52580-0.486102.581701.53030K562NELFE
CPS1ENSG00000021826.10493.55620381.791800.370302.732501.80140K562SRPK2
CPS1ENSG00000021826.10351.43940240.579800.546703.750102.23060K562SSB
CPS1ENSG00000021826.10253.85060466.01610-0.876403.722601.96870K562SUPT6H
CPS1ENSG00000021826.10198.85600277.63790-0.481502.393401.63060K562SYNCRIP
CPS1ENSG00000021826.10203.88860334.74720-0.715302.798301.69830K562TRA2A
CPS1ENSG00000021826.10292.90300427.14060-0.544303.262101.87900K562TROVE2
CPS1ENSG00000021826.10307.72300232.954700.401502.007601.32360K562U2AF2
CPS1ENSG00000021826.10220.34570342.60580-0.636804.175903.09310K562WDR3
CPS1ENSG00000021826.10257.39270356.29240-0.469103.185702.28250K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for CPS1 is not available on ENCORE database.





3 RBPs can affect the splicing of CPS1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SECPS1ENSG00000021826.10chr2+2114971902114972852114811462114812652115024252115025670.134000.002290.04065includedHepG2U2AF1
SECPS1ENSG00000021826.10chr2+211384274211384394211342405211342490211421442211421583-0.194000.001970.03606excludedHepG2U2AF1
SECPS1ENSG00000021826.10chr2+2114146172114147452113842742113843942114214422114215830.223000.001300.03149includedHepG2SRSF1
A5SSCPS1ENSG00000021826.10chr2+2113842742113845082113842742113843942114214422114215830.373000.000320.07553longerK562FXR2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for CPS1 is not avaliable on ENCORE database.