UPF2

General Information

Gene Name       : UPF2
Gene ID             : ENSG00000151461.19
Essential Gene : Yes

Functions

Localization(RBPImage: UPF2)

Domains (AlphaFold: UPF2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878UPF2ENSG00000151461.1936.2130.2533.23ENCSR000AEF
HepG2UPF2ENSG00000151461.1910.3314.3012.32ENCSR985KAT
K562UPF2ENSG00000151461.1921.0125.3323.17ENCSR000AEO

Assays

2 Released experiments are available on ENCORE database.

Assay TypeExp_NameENCODE IDTarget labelBiosampleStatusLinked AntibodyControlsMethodNote
knockdown followed by RNA-seq UPF2-BGKLV21-K562ENCSR810FHYUPF2K562ReleasedENCSR438MDN   shRNAKD% = 82.7,85.4
knockdown followed by RNA-seq UPF2-BGHLV17-HepG2ENCSR318OXMUPF2HepG2ReleasedENCSR856ZRV   shRNAKD% = 23.2,35.8






  eCLIP  

No eCLIP experiment available



  Antibody Validation  
  GeneName    Antibody_DCC_ID    Product_ID    Lot_ID    Phosphate    HepG2 Primary Validation    K562 Primary Validation    HepG2 Secondary Validation    K562 Secondary Validation  
UPF2ENCAB821QZMA303-929A1BGKLV21-65, Released, ENCODE3


  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
UPF2K562shRNABGKLV19-61,BGKLV19-62BGKLV19-1,BGKLV19-2NotSatisfiedENCODE3
UPF2K562shRNAENCSR810FHYENCSR438MDNUPF2_BGKLV21-65B,UPF2_BGKLV21-66BNT_BGKLV21-1B,NT_BGKLV21-2B82.7,85.4ReleasedENCODE3
UPF2HepG2shRNABGHLV16-65,BGHLV16-66BGHLV16-1,BGHLV16-2NotSatisfiedENCODE3
UPF2HepG2shRNAENCSR318OXMENCSR856ZRVUPF2_BGHLV17_39,UPF2_BGHLV17_40NT_BGHLV17_63,NT_BGHLV17_6423.2,35.8ReleasedENCODE3
UPF2HepG2CRISPRBGHcLV12-81,BGHcLV12-82BGHcLV12-1,BGHcLV12-20.0,0.0NotSatisfiedENCODE4
UPF2HepG2CRISPRBGHcLV12-83,BGHcLV12-84BGHcLV12-1,BGHcLV12-20.0,0.0NotSatisfiedENCODE4


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  
    UPF2: Click to RBP Image Database
  • Nuclei
  • Nucleoplasm
  • Mutually Exclusive from Nucleolus
  • Speckles
  • Cytoplasm
  • Compartment/Organelle
  • Unknown Cyto Foci
  • Cytosolic
  • Nuclear release mitosis












    • RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela
    UPF2Product_ID: A303-929A
    Lot_ID: 1
    Source: Bethyl Labs
    Target Name: UPF2-human    		 UPF2-K562_Secondary_Western.png<br>Caption: Western blot following shRNA against UPF2 in K562 whole cell lysate using UPF2 specific antibody. Lane 1 is a ladder, lane 2 is K562 non-targeting control knockdown, lane 3 and 4 are two different shRNAs against UPF2.UPF2 protein appears as the green band, Tubulin serves as a control and appears in red.








    RNA Targets

    • eCLIP assay for UPF2 is not avaliable on ENCORE database.



    Proteins bound to RNA
    • UPF2 RNA is bound by 25 proteins.  







    eCLIP assay for UPF2 is not avaliable on ENCORE database.





    25 proteins are bound to UPF2 RNA:

    Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
    chr101196213211962161-3'-UTR,intron-Distal3.406953.07801K562UPF1
    chr101196264911962706-3'-UTR,intron-Distal3.200595.75802K562UPF1
    chr101196251911962587-3'-UTR,intron-Distal3.103115.44101K562UPF1
    chr101208477012084824-5'-UTR,intron-Distal4.946857.20664HepG2NCBP2
    chr101207739112077441-5'-UTR,CDS,intron-Distal,intron-Proximal3.329383.28035HepG2NCBP2
    chr101207742412077430-5'-UTR,intron-Distal3.703954.24220K562ZNF622
    chr101208475512084820-5'-UTR,intron-Distal6.3743018.52282K562UCHL5
    chr101208475612084816-5'-UTR,intron-Distal4.2956413.24094K562ZNF622
    chr101208476112084823-5'-UTR,intron-Distal3.934074.06415K562TRA2A
    chr101208474812084770-5'-UTR,intron-Distal4.398145.05409HepG2NCBP2
    chr101198514411985165-CDS,intron-Distal3.161094.51789K562UCHL5
    chr101207729312077381-CDS,intron-Distal4.5738814.48434K562UCHL5
    chr101207713712077211-CDS,intron-Distal3.087836.99827K562PUM1
    chr101207129012071355-CDS,intron-Distal4.479024.74293HepG2ZNF800
    chr101197861411978645-CDS,intron-Distal3.509635.04943K562ZNF622
    chr101207135512071475-CDS,intron-Distal4.0967910.07770HepG2ZNF800
    chr101207109312071232-CDS,intron-Distal4.5773013.81550K562TRA2A
    chr101207135312071479-CDS,intron-Distal4.298558.42676K562MTPAP
    chr101207110412071141-CDS,intron-Distal4.004593.28989K562RBM15
    chr101207128012071358-CDS,intron-Distal3.6854012.78405K562PUM1
    chr101207137512071442-CDS,intron-Distal3.884876.27464K562TRA2A
    chr101207124712071312-CDS,intron-Distal5.1782216.95500K562UCHL5
    chr101205608112056169-CDS,intron-Distal3.232863.17744HepG2GRWD1
    chr101207102412071087-CDS,intron-Distal3.918128.08603HepG2BCLAF1
    chr101207109512071192-CDS,intron-Distal3.3097019.50455K562ZNF622
    chr101202103112021087-CDS,intron-Distal,intron-Proximal4.969287.36776HepG2PRPF8
    chr101198507811985156-CDS,intron-Distal3.9883910.31073K562ZNF622
    chr101207135512071379-CDS,intron-Distal3.5945912.45717K562ZNF622
    chr101204368912043800-CDS,intron-Distal4.523406.65960HepG2BCLAF1
    chr101207137812071524-CDS,intron-Distal,intron-Proximal3.0737813.14163K562RBM15
    chr101207713712077224-CDS,intron-Distal3.603974.17990K562CPSF6
    chr101207705512077108-CDS,intron-Distal,intron-Proximal3.760176.49817K562RBM15
    chr101207714312077224-CDS,intron-Distal6.0542715.43541K562TRA2A
    chr101198507611985144-CDS,intron-Distal4.3403111.93878K562UCHL5
    chr101207148312071524-CDS,intron-Distal,intron-Proximal4.509894.38106HepG2PPIG
    chr101207075612070829-CDS,intron-Distal4.972655.64533K562TRA2A
    chr101207148712071523-CDS,intron-Distal3.9051010.01989K562ZNF622
    chr101207150912071524-CDS,intron-Distal,intron-Proximal4.026925.59815K562TRA2A
    chr101207128612071355-CDS,intron-Distal3.8528614.75990K562ZNF622
    chr101198467111984710-CDS,intron-Distal5.023407.05570HepG2BCLAF1
    chr101207141212071473-CDS,intron-Distal3.8276410.84701K562UCHL5
    chr101207139912071437-CDS,intron-Distal3.611844.46864HepG2BCLAF1
    chr101207140412071472-CDS,intron-Distal3.258463.79741HepG2GRWD1
    chr101207103512071097-CDS,intron-Distal4.605415.14756K562RBM15
    chr101199848611998522-CDS,intron-Distal3.645869.25079K562ZNF622
    chr101207705912077113-CDS,intron-Distal3.7419610.72084K562ZNF622
    chr101207135512071458-CDS,intron-Distal4.185366.23486HepG2FXR2
    chr101207705712077133-CDS,intron-Distal,intron-Proximal5.5334421.07039K562UCHL5
    chr101198507811985151-CDS,intron-Distal5.176666.58593HepG2BCLAF1
    chr101207705312077120-CDS,intron-Distal,intron-Proximal5.270706.76175HepG2PPIG
    chr101207708212077140-CDS,intron-Distal5.8735825.14802K562TRA2A
    chr101200930112009355-CDS,intron-Distal,intron-Proximal4.591955.33214K562PRPF8
    chr101207149812071521-CDS,intron-Distal4.570809.48722K562UCHL5
    chr101199848011998521-CDS,intron-Distal3.805354.17155HepG2BCLAF1
    chr101207102512071093-CDS,intron-Distal3.8783315.56303K562UCHL5
    chr101207722412077306-CDS,intron-Distal4.7835713.81550K562TRA2A
    chr101207109312071176-CDS,intron-Distal3.6835813.36249K562UCHL5
    chr101207706112077266-CDS,intron-Distal3.990434.98043HepG2TRA2A
    chr101204190812041953-CDS,intron-Distal3.465138.71976K562ZNF622
    chr101207131212071412-CDS,intron-Distal4.1000016.00088K562UCHL5
    chr101200117412001210-CDS,intron-Distal4.020819.70241K562ZNF622
    chr101198507011985166-CDS,intron-Distal3.656588.14955K562GRWD1
    chr101207102912071094-CDS,intron-Distal5.0318320.37416K562ZNF622
    chr101207130112071355-CDS,intron-Distal4.365824.67436K562GRWD1
    chr101207705612077082-CDS,intron-Distal,intron-Proximal4.6993314.08230K562TRA2A
    chr101204190812041996-CDS,intron-Distal3.756576.18214HepG2GRWD1
    chr101198467611984736-CDS,intron-Distal3.239748.95936K562ZNF622
    chr101204657712046626-CDS,intron-Distal3.606008.64848K562UCHL5
    chr101207103012071094-CDS,intron-Distal3.741555.59924K562GRWD1
    chr101207139112071523-CDS,intron-Distal4.226755.59033HepG2FTO
    chr101207137912071472-CDS,intron-Distal4.3094321.65691K562ZNF622
    chr101199718111997238-CDS,intron-Distal,intron-Proximal4.127143.85435K562PRPF8
    chr101207110812071169-CDS,intron-Distal4.003953.79347HepG2GRWD1
    chr101199037011990389-CDS,intron-Distal4.381556.95786K562UCHL5
    chr101208463812084707-intron-Distal4.075234.10339HepG2CSTF2T
    chr101206821412068276-intron-Distal3.694063.02234K562KHSRP
    chr101205236712052426-intron-Distal3.846023.16028HepG2SUGP2
    chr101199683311996896-intron-Distal4.012783.66668K562KHSRP
    chr101196755811967606-intron-Distal3.885023.63454HepG2SUGP2
    chr101206927112069334-intron-Distal3.109893.20028K562TARDBP
    chr101206517212065275-intron-Distal3.180013.48890K562KHSRP
    chr101196749511967531-intron-Distal3.977533.54208HepG2SUGP2
    chr101206448312064665-intron-Distal3.020458.53706K562KHSRP
    chr101201869412018758-intron-Distal4.693544.30178K562PTBP1
    chr101206933412069398-intron-Distal4.202413.60944K562TARDBP
    chr101200946312009511-intron-Distal,intron-Proximal5.493205.40008K562SF3B4
    chr101208419912084302-intron-Distal4.012823.70058K562CSTF2T
    chr101196862711968697-intron-Distal4.685056.05753HepG2SUGP2
    chr101203979812039942-intron-Distal,intron-Proximal5.009055.20135HepG2QKI
    chr101201860612018750-intron-Distal3.601684.03284K562MATR3
    chr101204182512041902-intron-Distal,intron-Proximal3.995623.12843K562PRPF8
    chr101205915812059228-intron-Distal3.090073.90146K562KHSRP
    chr101198921611989304-intron-Distal3.433435.35459K562KHSRP
    chr101201863912018761-intron-Distal4.415873.41738HepG2PTBP1
    chr101196768411967771-intron-Distal3.292905.83578HepG2SUGP2
    chr101196839211968506-intron-Distal4.309203.90241K562MATR3
    chr101203720312037336-intron-Distal3.254853.09339K562MATR3
    chr101205928312059390-intron-Distal3.268735.34873K562KHSRP
    chr101198954311989603-intron-Distal3.521203.37821K562XRCC6
    chr101196876511968872-intron-Distal3.753506.55984HepG2SUGP2
    chr101196393911964028-intron-Distal3.091593.23296HepG2SUGP2
    chr101196806811968125-intron-Distal3.185053.69184HepG2SUGP2
    chr101207035012070463-intron-Distal3.015995.40698K562KHSRP
    chr101205253212052663-intron-Distal4.446513.72005K562MATR3
    chr101203526512035364-intron-Distal3.931836.83037K562KHSRP
    chr101205187712051928-intron-Distal3.846023.16028HepG2SUGP2
    chr101206827612068365-intron-Distal4.210574.76003K562KHSRP
    ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




    eCLIP assay for UPF2 is not avaliable on ENCORE database.



    Diffrential Expression
    • 3,413 differentially expressed genes after Knockdown/Knockout UPF2 protein.  





    • 57 RBPs can affect the levels of UPF2.  







    3,413 differentially expressed genes after Knockdown/Knockout UPF2 protein :

    Only display 100 entries as example. Please click "View All" button to see all 3,413 entries.     

    Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
    NFYAENSG00000001167.10763.728401050.97300-0.460602.470001.52450HepG2UPF2
    LAP3ENSG00000002549.8605.146801576.44490-1.3813016.8460014.38750HepG2UPF2
    CD99ENSG00000002586.132067.795101433.387400.528602.973601.93170HepG2UPF2
    TFPIENSG00000003436.102142.919204971.51590-1.214108.312306.52390HepG2UPF2
    RBM5ENSG00000003756.122709.745401874.661800.531404.224602.96880HepG2UPF2
    SLC7A2ENSG00000003989.121847.873303189.79840-0.787605.929004.41980HepG2UPF2
    ARF5ENSG00000004059.61033.75520597.218700.791502.748701.74760HepG2UPF2
    PLXND1ENSG00000004399.8918.680401411.87040-0.620002.610901.63680HepG2UPF2
    FKBP4ENSG00000004478.5805.011301554.12070-0.949009.524507.60770HepG2UPF2
    RBM6ENSG00000004534.104311.835802374.549200.860509.613007.68370HepG2UPF2
    RECQLENSG00000004700.11490.69930800.83550-0.706702.862001.84000HepG2UPF2
    CDC27ENSG00000004897.71679.391502371.56950-0.497902.661901.67710HepG2UPF2
    SLC25A5ENSG00000005022.52866.139404024.95740-0.489903.705902.52780HepG2UPF2
    DHX33ENSG00000005100.8710.306501319.46490-0.893407.505405.79260HepG2UPF2
    LIG3ENSG00000005156.7489.16470693.48930-0.503602.876901.85280HepG2UPF2
    ACSM3ENSG00000005187.71497.66580479.004501.6445023.8394021.08520HepG2UPF2
    AC004381.6ENSG00000005189.15354.79920218.505900.699203.479602.34690HepG2UPF2
    SPPL2BENSG00000005206.12422.57710251.212900.750202.891301.86470HepG2UPF2
    FAM214BENSG00000005238.15189.37710104.519900.857402.559801.59690HepG2UPF2
    CROTENSG00000005469.7450.96140226.716200.992006.315604.75620HepG2UPF2
    ZNF195ENSG00000005801.12651.99410397.957300.712104.095902.86400HepG2UPF2
    MYCBP2ENSG00000005810.13583.769001132.96640-0.956607.805306.06560HepG2UPF2
    ASB4ENSG00000005981.843.54900122.50840-1.492205.106603.71840HepG2UPF2
    C19orf60ENSG00000006015.13110.6340042.485301.380702.885301.85970HepG2UPF2
    OSBPL7ENSG00000006025.7357.46900181.638700.976604.630703.31470HepG2UPF2
    CX3CL1ENSG00000006210.62977.023601509.072400.980104.990103.61880HepG2UPF2
    TNFRSF12AENSG00000006327.9761.73620466.375700.707704.419203.13060HepG2UPF2
    JHDM1DENSG00000006459.6511.694201140.19400-1.1559011.177509.08930HepG2UPF2
    KIAA0100ENSG00000007202.102402.175203197.99640-0.412802.432201.49450HepG2UPF2
    PAX6ENSG00000007372.165.6710033.20460-2.549704.173902.92810HepG2UPF2
    RHBDF1ENSG00000007384.11281.26820143.213400.973704.053602.82890HepG2UPF2
    BAIAP3ENSG00000007516.9133.0698062.212501.096802.997701.95300HepG2UPF2
    CDKL5ENSG00000008086.619.3844076.22880-1.975402.360201.43900HepG2UPF2
    CDK11AENSG00000008128.18651.87350444.327100.552902.529401.57270HepG2UPF2
    CYTH3ENSG00000008256.11107.20340177.40070-0.726702.292001.38410HepG2UPF2
    AASSENSG00000008311.10229.96720363.10680-0.659002.317101.40440HepG2UPF2
    PLEKHG6ENSG00000008323.11309.20530176.505700.808702.992001.94790HepG2UPF2
    CRY1ENSG00000008405.7206.65350343.86730-0.734603.295602.19580HepG2UPF2
    NFIXENSG00000008441.12207.54300326.81510-0.655103.191302.11190HepG2UPF2
    ST3GAL1ENSG00000008513.10521.98860840.45310-0.687104.725003.39580HepG2UPF2
    IL32ENSG00000008517.122797.120801616.062500.791407.254305.57840HepG2UPF2
    MAPK8IP2ENSG00000008735.10141.6624060.693301.222702.904901.87700HepG2UPF2
    RPS20ENSG00000008988.56325.922204862.165000.379602.275701.37190HepG2UPF2
    CSDE1ENSG00000009307.115501.087407942.69850-0.529903.611802.45350HepG2UPF2
    UBE3CENSG00000009335.13729.729401149.15530-0.655104.470403.17530HepG2UPF2
    REV3LENSG00000009413.11773.814501259.93480-0.703304.665603.34200HepG2UPF2
    VTA1ENSG00000009844.111055.085101480.00620-0.488202.306201.39590HepG2UPF2
    MLXIPLENSG00000009950.115716.377401837.530901.6372019.4162016.78980HepG2UPF2
    BAZ1BENSG00000009954.61991.448002794.74050-0.488902.925001.89310HepG2UPF2
    CD9ENSG00000010278.789.57350154.50590-0.786502.543201.58390HepG2UPF2
    NCAPD2ENSG00000010292.82067.790303325.03780-0.685306.618805.02120HepG2UPF2
    CD4ENSG00000010610.549.2071094.30030-0.938402.636101.65800HepG2UPF2
    FYNENSG00000010810.13384.89690826.98550-1.103409.077707.22130HepG2UPF2
    CLCN6ENSG00000011021.171758.132201143.039600.621104.350103.07440HepG2UPF2
    NME2ENSG00000011052.17393.90490166.873901.239003.813202.62060HepG2UPF2
    AKAP8LENSG00000011243.131126.78880766.060500.556603.273102.17710HepG2UPF2
    UTP18ENSG00000011260.9515.71720919.63250-0.834505.700704.22010HepG2UPF2
    PTBP1ENSG00000011304.122890.416203746.31890-0.374202.598101.62620HepG2UPF2
    PIK3C2AENSG00000011405.91107.543902153.51230-0.959305.531504.08040HepG2UPF2
    ANLNENSG00000011426.6980.847202204.64680-1.1684013.8069011.49300HepG2UPF2
    MAP4K3ENSG00000011566.10853.255301633.39770-0.936805.400503.97150HepG2UPF2
    BRCA1ENSG00000012048.15610.42330899.23470-0.558903.082402.02360HepG2UPF2
    MBTPS2ENSG00000012174.7396.24010643.51310-0.699603.561902.41300HepG2UPF2
    EXTL3ENSG00000012232.4499.10440690.36560-0.468002.669801.68240HepG2UPF2
    NR1H4ENSG00000012504.91880.84330688.492901.4498019.9753017.31590HepG2UPF2
    CALCOCO1ENSG00000012822.11806.76830541.087800.576203.661902.49350HepG2UPF2
    UBR7ENSG00000012963.9434.75830630.97200-0.537402.373201.44950HepG2UPF2
    CLDN11ENSG00000013297.676.84340162.53820-1.080804.173802.92810HepG2UPF2
    CLK1ENSG00000013441.111761.845101032.901600.770307.149105.48540HepG2UPF2
    ANGEL1ENSG00000013523.5383.49470578.35000-0.592703.073102.01640HepG2UPF2
    UFL1ENSG00000014123.9392.69120833.81080-1.086308.939607.09640HepG2UPF2
    CCDC88CENSG00000015133.14219.39530321.32610-0.550502.516401.56260HepG2UPF2
    ZMYND11ENSG00000015171.14511.03990982.83020-0.943507.285405.60430HepG2UPF2
    CHDHENSG00000016391.62672.815501966.260000.442802.487501.53930HepG2UPF2
    GLT8D1ENSG00000016864.121589.791001037.263900.616003.941402.73330HepG2UPF2
    ATP2C1ENSG00000017260.15883.887901352.45010-0.613603.655902.48840HepG2UPF2
    SLC38A5ENSG00000017483.10407.12200713.75300-0.810005.905604.40250HepG2UPF2
    WWTR1ENSG00000018408.10982.082101473.48080-0.585303.501802.36390HepG2UPF2
    AGPSENSG00000018510.81296.905702568.82410-0.9860010.080908.10660HepG2UPF2
    CYP24A1ENSG00000019186.5140.69320656.62950-2.2225029.7695026.74490HepG2UPF2
    SYT13ENSG00000019505.36.8895034.85540-2.338903.239002.14850HepG2UPF2
    MRE11AENSG00000020922.8339.17320543.36290-0.679903.449702.32270HepG2UPF2
    PLEKHB1ENSG00000021300.9596.904101222.78220-1.034608.053906.29620HepG2UPF2
    SPASTENSG00000021574.7453.09750830.63830-0.874406.344504.78170HepG2UPF2
    CPS1ENSG00000021826.10702.264101049.05390-0.579003.415702.29390HepG2UPF2
    NDUFS1ENSG00000023228.92372.583203480.69250-0.552903.482002.34870HepG2UPF2
    RB1CC1ENSG00000023287.8750.203601301.40090-0.794702.964701.92420HepG2UPF2
    AKAP11ENSG00000023516.7503.067801024.20360-1.025703.672902.50180HepG2UPF2
    DERAENSG00000023697.8342.39670531.71680-0.635002.629901.65280HepG2UPF2
    GCLMENSG00000023909.5248.13300399.61060-0.687503.075202.01760HepG2UPF2
    DEPDC1ENSG00000024526.12225.97230535.15010-1.243809.569407.64490HepG2UPF2
    NR1H3ENSG00000025434.14478.59410322.177100.570802.332601.41730HepG2UPF2
    NCAPH2ENSG00000025770.14669.59580457.711800.548802.234801.33850HepG2UPF2
    RNASET2ENSG00000026297.112465.795701887.595300.385402.376301.45190HepG2UPF2
    VRK2ENSG00000028116.12208.74740372.25340-0.834504.333003.06050HepG2UPF2
    BCLAF1ENSG00000029363.112403.585803925.22710-0.707602.513301.55970HepG2UPF2
    HMGB3ENSG00000029993.10754.426501056.24750-0.485502.442801.50280HepG2UPF2
    NUP160ENSG00000030066.9882.930401874.08390-1.0858011.150409.06890HepG2UPF2
    SLC4A7ENSG00000033867.12268.04180811.35730-1.5979018.4530015.86450HepG2UPF2
    TMSB10ENSG00000034510.45281.681904160.489900.344102.410601.47930HepG2UPF2
    Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

    *: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
    **: "-log(0)" was displayed as "99999.99999".





    57 RBPs can affect the gene expression of UPF2 :

    Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
    UPF2ENSG00000151461.15679.74490890.94240-0.390302.059001.59280HepG2AKAP1
    UPF2ENSG00000151461.15409.94660601.58770-0.553303.330402.34590HepG2BCLAF1
    UPF2ENSG00000151461.15854.594501261.93580-0.562305.926105.08990HepG2BOP1
    UPF2ENSG00000151461.15886.37790700.392100.339702.051801.37920HepG2CIRBP
    UPF2ENSG00000151461.15593.20780751.59770-0.341403.349702.63070HepG2CKAP4
    UPF2ENSG00000151461.15815.106001011.05070-0.310803.097802.32010HepG2DAZAP1
    UPF2ENSG00000151461.15480.11520692.73010-0.528905.510904.54800HepG2DNAJC21
    UPF2ENSG00000151461.15526.91910686.65120-0.382003.374202.66710HepG2DNAJC2
    UPF2ENSG00000151461.15511.85480704.84390-0.461602.574602.00280HepG2EIF2S1
    UPF2ENSG00000151461.15914.293701313.29960-0.522504.164003.39000HepG2GPKOW
    UPF2ENSG00000151461.15542.05610699.36700-0.367602.437801.82870HepG2HNRNPA1
    UPF2ENSG00000151461.15746.39460929.25570-0.316102.605501.69580HepG2HNRNPA2B1
    UPF2ENSG00000151461.15592.52650777.92920-0.392802.662501.98150HepG2HNRNPC
    UPF2ENSG00000151461.15579.10100772.78510-0.416304.525803.76660HepG2HNRNPU
    UPF2ENSG00000151461.15646.92960789.37220-0.287102.920302.16940HepG2ILF2
    UPF2ENSG00000151461.151140.25050865.237400.398104.887003.89030HepG2PRPF4
    UPF2ENSG00000151461.15383.27160525.13230-0.454302.363701.61430HepG2PRPF8
    UPF2ENSG00000151461.15705.15810957.07560-0.440703.560302.89550HepG2PUF60
    UPF2ENSG00000151461.15945.99220784.846700.269302.243201.68120HepG2RECQL
    UPF2ENSG00000151461.151514.259101212.662300.320304.272903.68980HepG2SRFBP1
    UPF2ENSG00000151461.15872.01560669.432600.381304.216203.56180HepG2SRSF9
    UPF2ENSG00000151461.15617.09620757.62070-0.296002.547302.00180HepG2TRIM56
    UPF2ENSG00000151461.151352.11010952.303700.505603.089302.42770HepG2U2AF1
    UPF2ENSG00000151461.15289.32900400.30310-0.468402.415901.70590HepG2UCHL5
    UPF2ENSG00000151461.15299.44820620.52560-1.051208.055206.29620HepG2UPF2
    UPF2ENSG00000151461.151108.92740760.685300.543703.125401.77750HepG2XRCC5
    UPF2ENSG00000151461.15907.037701127.58020-0.314003.928903.30800HepG2ZNF622
    UPF2ENSG00000151461.152752.073202294.349100.262303.927503.27280K562AGGF1
    UPF2ENSG00000151461.152831.044402387.402700.245802.075901.50750K562AKAP8L
    UPF2ENSG00000151461.152718.043703288.38390-0.274803.459802.21710K562CPEB4
    UPF2ENSG00000151461.155142.231204326.652100.249002.909901.91050K562CELF1
    UPF2ENSG00000151461.151101.526001474.21300-0.420404.337502.99050K562DDX3X
    UPF2ENSG00000151461.154280.997203402.942200.331106.123605.20770K562DDX47
    UPF2ENSG00000151461.151154.863501494.68480-0.372104.300402.55370K562DDX6
    UPF2ENSG00000151461.152133.884201331.829500.680006.395504.43090K562EEF2
    UPF2ENSG00000151461.15952.481801286.84120-0.434103.530202.49240K562EFTUD2
    UPF2ENSG00000151461.151272.794801619.41520-0.347504.145302.64390K562EIF2S1
    UPF2ENSG00000151461.151768.111402132.70920-0.270501.980101.35370K562EIF2S2
    UPF2ENSG00000151461.151136.040401387.10620-0.288102.619601.50900K562EIF4B
    UPF2ENSG00000151461.151902.360102814.64830-0.565204.041003.00180K562FIP1L1
    UPF2ENSG00000151461.152454.869101763.903400.476803.355902.56370K562G3BP2
    UPF2ENSG00000151461.151946.472602842.33220-0.546203.925203.02880K562GRSF1
    UPF2ENSG00000151461.152239.128701751.796800.354003.710202.46380K562HNRNPA1
    UPF2ENSG00000151461.152463.782403816.33470-0.631304.599003.57840K562HSPD1
    UPF2ENSG00000151461.151460.902501873.13590-0.358603.245401.92690K562IGF2BP3
    UPF2ENSG00000151461.153275.373102533.531200.370402.398801.63900K562KIF1C
    UPF2ENSG00000151461.151865.886902465.74240-0.402204.555703.41330K562METAP2
    UPF2ENSG00000151461.152806.441201989.387600.496303.840902.75620K562NAA15
    UPF2ENSG00000151461.151993.244203194.90580-0.680705.196604.01610K562PPIG
    UPF2ENSG00000151461.151021.763001434.99550-0.490003.140702.16880K562PSIP1
    UPF2ENSG00000151461.152276.513301880.689300.275502.024501.43960K562PTBP1
    UPF2ENSG00000151461.153578.490502367.445000.595908.273507.38330K562PUS1
    UPF2ENSG00000151461.152959.620702306.887000.359405.328204.52970K562RBM15
    UPF2ENSG00000151461.151808.064902262.70030-0.323603.107501.97520K562SRSF4
    UPF2ENSG00000151461.152300.132301819.052000.338403.849502.87960K562SYNCRIP
    UPF2ENSG00000151461.151454.416101799.95360-0.307502.902102.06160K562TIA1
    UPF2ENSG00000151461.152375.789601710.095700.474204.035802.66590K562U2AF1
    UPF2ENSG00000151461.152206.051201766.058500.320803.456402.56000K562U2AF2
    UPF2ENSG00000151461.153881.633402709.446300.5186014.2204012.74510K562UPF1
    UPF2ENSG00000151461.15793.810401859.44440-1.2280031.8697027.49150K562UPF2
    UPF2ENSG00000151461.153086.074602410.809900.356207.423206.10120K562WDR43
    Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

    *: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
    **: "-log(0)" was displayed as "99999.99999".






    The Knockdown/knockout RNA-Seq assay for UPF2 is not available on ENCORE database.





    4 RBPs can affect the splicing of UPF2 :

    Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
    SEUPF2ENSG00000151461.15chr10-1196892011969014119620201196330611971863119719840.259000.000000.00003includedHepG2U2AF1
    SEUPF2ENSG00000151461.15chr10-120436741204382412041904120420081204652812046726-0.226000.002880.04888excludedHepG2U2AF1
    SEUPF2ENSG00000151461.15chr10-120436741204382412041904120420081204652812046726-0.181000.000020.00040excludedHepG2U2AF2
    SEUPF2ENSG00000151461.15chr10-120436741204382412041904120420081204652812046726-0.055000.009990.08120excludedK562AQR
    SEUPF2ENSG00000151461.15chr10-119940641199424811990388119905071199723011997506-0.080000.000040.00073excludedK562AQR
    A3SSUPF2ENSG00000151461.15chr10-1197854311978742119785431197871111984663119848270.069000.001010.00699longerK562AQR
    A3SSUPF2ENSG00000151461.15chr10-1198506211985250119850621198516711990367119905700.063000.000010.00007longerK562AQR
    A3SSUPF2ENSG00000151461.15chr10-1200600712006170120060071200612412009339120095130.209000.000000.00000longerK562AQR
    A3SSUPF2ENSG00000151461.15chr10-1203967012039825120396701203975612041904120420080.057000.000010.00010longerK562AQR
    A3SSUPF2ENSG00000151461.15chr10-1205602212056211120560221205618312070743120715230.142000.000000.00000longerK562AQR
    A3SSUPF2ENSG00000151461.15chr10-119903671199055711990367119905071199723011997506-0.546000.006220.03501shorterK562AQR
    MXEUPF2ENSG00000151461.15chr10-12041904120420081204367412043824120396701203975612046528120467260.113000.011790.072251includedK562AQR
    MXEUPF2ENSG00000151461.15chr10-12041904120420081204367412043848120396701203975612046528120467260.072000.000620.005971includedK562AQR
    MXEUPF2ENSG00000151461.15chr10-1199038811990507119940641199424811985062119851671199723011997506-0.106000.000070.000862includedK562AQR
    MXEUPF2ENSG00000151461.15chr10-1204190412042008120436741204382412039670120397561204652812046726-0.245000.000400.007782includedHepG2SFPQ
    MXEUPF2ENSG00000151461.15chr10-1204190412042008120436741204382412039670120397561204652812046726-0.296000.000020.000312includedHepG2U2AF2

    *: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
    **: "-log(0)" was displayed as "99999.99999".





    The Knockdown/knockout RNA-Seq assay for UPF2 is not avaliable on ENCORE database.