GCLM

General Information

Gene Name       : GCLM
Gene ID             : ENSG00000023909.9
Essential Gene : No

Functions

Localization

Domains (AlphaFold: GCLM)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878GCLMENSG00000023909.96.396.456.42ENCSR000AEF
HepG2GCLMENSG00000023909.913.1220.4916.80ENCSR985KAT
K562GCLMENSG00000023909.923.7318.3521.04ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for GCLM is not avaliable on ENCORE database.



Proteins bound to RNA
  • GCLM RNA is bound by 28 proteins.  







eCLIP assay for GCLM is not avaliable on ENCORE database.





28 proteins are bound to GCLM RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr19435110394351164-3'-UTR,intron-Distal4.251713.25872K562IGF2BP1
chr19435287394352915-3'-UTR,intron-Distal3.168735.15194K562UPF1
chr19435418294354237-3'-UTR,intron-Distal3.023884.57444K562TIA1
chr19435439294354448-3'-UTR,intron-Distal6.6188326.53076K562LIN28B
chr19435286794352912-3'-UTR,intron-Distal3.482325.33418K562FAM120A
chr19435369794353721-3'-UTR,intron-Distal4.310634.22051K562UPF1
chr19435408294354152-3'-UTR,intron-Distal3.585425.22676K562IGF2BP1
chr19435095294350995-3'-UTR,intron-Distal4.168128.86906K562PUM2
chr19435386094353945-3'-UTR,intron-Distal4.199138.90657K562TIA1
chr19435230894352437-3'-UTR,intron-Distal4.0156819.08639K562UPF1
chr19435401294354090-3'-UTR,intron-Distal3.6564739.34886K562PUM2
chr19435392794353988-3'-UTR,intron-Distal4.258803.35973HepG2FUBP3
chr19435162294351693-3'-UTR,intron-Distal4.045046.99270K562IGF2BP1
chr19435407394354123-3'-UTR,intron-Distal3.012089.31029K562PABPC4
chr19435441994354498-3'-UTR,intron-Distal5.9611512.72366HepG2SUB1
chr19435434594354392-3'-UTR,intron-Distal6.1481421.82861K562LIN28B
chr19435277094352867-3'-UTR,intron-Distal4.9339622.44660K562FAM120A
chr19435410494354152-3'-UTR,intron-Distal4.612533.98488K562TIA1
chr19435293794353010-3'-UTR,intron-Distal3.549487.02949K562UPF1
chr19435402294354082-3'-UTR,intron-Distal3.363153.78871K562IGF2BP1
chr19435389294353946-3'-UTR,intron-Distal4.339494.43679K562IGF2BP1
chr19435293994352986-3'-UTR,intron-Distal3.804257.08510K562FAM120A
chr19435448994354578-3'-UTR,CDS,intron-Distal4.408244.24698K562IGF2BP1
chr19435434794354390-3'-UTR,intron-Distal4.340995.29045K562IGF2BP1
chr19435235194352394-3'-UTR,intron-Distal3.868876.56370K562FAM120A
chr19435082294350892-3'-UTR,intron-Distal4.6463923.52250K562PUM2
chr19435264194352682-3'-UTR,intron-Distal3.797003.80864K562FAM120A
chr19435443894354540-3'-UTR,intron-Distal3.9158721.97774K562PUM2
chr19437470794374847-5'-UTR,CDS,intron-Distal4.589127.70706HepG2RPS3
chr19437483294374909-5'-UTR,intron-Distal3.951495.23852K562DDX3X
chr19437486094374918-5'-UTR,intron-Distal3.495495.81611K562GEMIN5
chr19437461194374750-5'-UTR,CDS,intron-Distal3.7852010.85057K562DDX3X
chr19437469094374743-5'-UTR,CDS,intron-Distal3.365833.63681K562RBM15
chr19436331394363410-CDS,intron-Distal,intron-Proximal3.759226.79537K562AQR
chr19436718994367236-CDS,intron-Distal,intron-Proximal3.519435.02403K562SF3B4
chr19435460794354664-CDS,intron-Distal3.310803.67576K562IGF2BP2
chr19436234494362398-CDS,intron-Distal,intron-Proximal3.892645.60471HepG2U2AF2
chr19436704094367150-CDS,intron-Distal,intron-Proximal4.605909.27995K562PRPF8
chr19436339494363430-CDS,intron-Distal,intron-Proximal3.593394.98210K562SND1
chr19436338994363446-CDS,intron-Distal,intron-Proximal3.047834.00731K562UCHL5
chr19437452994374600-CDS,intron-Distal,intron-Proximal3.022744.22621HepG2PRPF8
chr19436224694362377-CDS,intron-Distal,intron-Proximal3.747458.83606K562SND1
chr19436344394363508-CDS,intron-Distal,intron-Proximal5.143396.40247K562SF3B4
chr19436913394369232-intron-Distal3.294628.14869K562CSTF2T
chr19436927694369371-intron-Distal3.619369.66830K562KHSRP
chr19436876094368844-intron-Distal4.365955.31406K562KHDRBS1
chr19437438094374571-intron-Distal,intron-Proximal3.211399.86732K562PRPF8
chr19436009694360149-intron-Distal,intron-Proximal4.001244.31512K562KHSRP
chr19437440694374554-intron-Distal,intron-Proximal6.5516126.47025K562EFTUD2
chr19437442494374570-intron-Distal,intron-Proximal3.928686.39201HepG2RBM22
chr19436329994363352-intron-Distal,intron-Proximal4.921843.78571K562GPKOW
chr19437022994370290-intron-Distal,intron-Proximal3.432635.20123K562KHSRP
chr19437442294374573-intron-Distal,intron-Proximal4.8926115.24697HepG2EFTUD2
chr19436723694367281-intron-Distal,intron-Proximal4.811915.40008K562SF3B4
chr19437395594374079-intron-Distal3.219383.81590K562HNRNPL
chr19436036394360406-intron-Distal,intron-Proximal3.609103.02234K562KHSRP
chr19437230894372435-intron-Distal3.987193.00997K562TAF15
chr19436937794369464-intron-Distal5.7241814.70731K562KHSRP
chr19437165794371733-intron-Distal3.207306.18396K562KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for GCLM is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for GCLM is not available on ENCORE database.

  • 108 RBPs can affect the levels of GCLM.  








The Knockdown/knockout RNA-Seq assay for GCLM is not available on ENCORE database.





108 RBPs can affect the gene expression of GCLM :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
GCLMENSG00000023909.5616.60090856.11440-0.473502.822002.28480HepG2AKAP1
GCLMENSG00000023909.5509.91700708.35860-0.474203.085902.25780HepG2ASCC1
GCLMENSG00000023909.5879.38060726.607600.275202.393301.74630HepG2AUH
GCLMENSG00000023909.5230.96350445.85220-0.948906.677205.18540HepG2BCCIP
GCLMENSG00000023909.5613.60820381.778000.684506.842005.70190HepG2CALR
GCLMENSG00000023909.5299.37910552.92920-0.885103.845302.93700HepG2CNOT7
GCLMENSG00000023909.5173.91720275.40800-0.663203.412202.22780HepG2CSTF2
GCLMENSG00000023909.5393.57670285.170200.464702.573401.69550HepG2DDX24
GCLMENSG00000023909.51229.11460704.490300.802908.007607.00870HepG2DDX6
GCLMENSG00000023909.5519.85920389.018700.418203.166402.44940HepG2DKC1
GCLMENSG00000023909.5432.83880268.369900.689504.003202.65580HepG2AGO1
GCLMENSG00000023909.5179.90270677.22240-1.9124030.0462028.22760HepG2EIF2S1
GCLMENSG00000023909.5386.05020272.248000.503802.624901.74210HepG2EIF3D
GCLMENSG00000023909.5585.24790748.40010-0.354801.827201.30340HepG2EIF4A3
GCLMENSG00000023909.51547.05110728.692101.086009.385308.15640HepG2EIF4B
GCLMENSG00000023909.5832.11350575.738200.531306.069604.91740HepG2EIF4G1
GCLMENSG00000023909.5163.29360243.26970-0.575102.912901.71260HepG2FAM120A
GCLMENSG00000023909.5496.15530755.13540-0.605904.769303.87650HepG2FXR1
GCLMENSG00000023909.5455.22100700.48250-0.621804.642203.79080HepG2G3BP1
GCLMENSG00000023909.5804.84460519.135700.632503.721102.98810HepG2GPKOW
GCLMENSG00000023909.5540.06300388.212100.476204.464703.24540HepG2HDGF
GCLMENSG00000023909.5333.53060709.34000-1.0887013.2014011.78310HepG2HNRNPK
GCLMENSG00000023909.5429.28160531.70870-0.308702.486201.84410HepG2HNRNPL
GCLMENSG00000023909.5233.96820402.76940-0.783607.846406.86440HepG2HNRNPU
GCLMENSG00000023909.51093.82830510.727901.0987012.7995010.26750HepG2HSPD1
GCLMENSG00000023909.5935.94490712.019300.394402.545801.89610HepG2IGF2BP2
GCLMENSG00000023909.5277.77800411.41500-0.566704.890703.93800HepG2ILF2
GCLMENSG00000023909.5452.13040716.18060-0.663604.317203.03730HepG2KHSRP
GCLMENSG00000023909.5380.70060759.62200-0.996609.935308.79750HepG2MATR3
GCLMENSG00000023909.5209.33410333.81180-0.673204.031003.06050HepG2MSI2
GCLMENSG00000023909.5244.90370505.08600-1.044303.400302.31830HepG2MTPAP
GCLMENSG00000023909.5524.06250777.51120-0.569104.131003.36210HepG2NCBP2
GCLMENSG00000023909.5385.34550578.75980-0.586805.855704.74970HepG2NOL12
GCLMENSG00000023909.51256.09300505.238701.3138011.644509.79240HepG2PABPC1
GCLMENSG00000023909.5434.33370692.40560-0.672805.451004.44740HepG2PABPC4
GCLMENSG00000023909.5253.78930359.23750-0.501303.328002.52590HepG2PPIL4
GCLMENSG00000023909.5259.78850334.29320-0.363801.965901.30580HepG2PRPF4
GCLMENSG00000023909.5695.21070552.448700.331501.894801.38800HepG2PUF60
GCLMENSG00000023909.5844.15370586.415700.525507.103406.24280HepG2PUM1
GCLMENSG00000023909.5393.69350680.53450-0.789609.848908.77180HepG2QKI
GCLMENSG00000023909.5690.90780463.443000.576005.910204.71540HepG2RBM15
GCLMENSG00000023909.51304.52140697.230800.9037019.7047018.58220HepG2RBM22
GCLMENSG00000023909.5794.22530617.597900.362801.963501.38790HepG2RBM25
GCLMENSG00000023909.5528.85270699.25740-0.403003.588302.98870HepG2NELFE
GCLMENSG00000023909.5533.52100651.20540-0.287602.119701.57120HepG2RECQL
GCLMENSG00000023909.5674.09290393.077500.778004.899202.85430HepG2RTF1
GCLMENSG00000023909.5257.77570358.68190-0.476603.239302.55290HepG2SAFB2
GCLMENSG00000023909.51164.01050490.406901.2470021.5288019.76780HepG2SF3B1
GCLMENSG00000023909.5426.11960529.64450-0.313802.414501.75300HepG2SLBP
GCLMENSG00000023909.5335.53540418.28020-0.318001.923501.37120HepG2SMN1
GCLMENSG00000023909.5621.57010368.520900.754105.336103.97660HepG2SMNDC1
GCLMENSG00000023909.52371.18550787.521101.5901089.0916087.27180HepG2SRFBP1
GCLMENSG00000023909.5998.09930682.814000.547607.193506.51430HepG2SRSF1
GCLMENSG00000023909.51608.82930555.481401.5341012.9215011.88620HepG2SRSF9
GCLMENSG00000023909.5894.90190683.797700.388102.379001.89590HepG2SSB
GCLMENSG00000023909.5582.47420337.570600.786904.764603.18000HepG2SUB1
GCLMENSG00000023909.5651.36760436.387900.577803.637502.87830HepG2SUPV3L1
GCLMENSG00000023909.5305.51520391.35260-0.357201.984701.54630HepG2TIAL1
GCLMENSG00000023909.5559.14120362.758900.624103.380901.76590HepG2TRA2A
GCLMENSG00000023909.5235.02760394.86510-0.748507.392006.54620HepG2TRIM56
GCLMENSG00000023909.593.45920257.79110-1.4638011.7848010.23660HepG2UCHL5
GCLMENSG00000023909.5350.64650483.83950-0.464503.846403.04310HepG2UPF1
GCLMENSG00000023909.5248.13300399.61060-0.687503.075202.01760HepG2UPF2
GCLMENSG00000023909.5233.95800429.57590-0.876706.225305.15250HepG2XRN2
GCLMENSG00000023909.5568.80680329.900600.7858010.598609.42600HepG2ZC3H8
GCLMENSG00000023909.5788.80320532.132100.567808.387507.56840HepG2ZNF622
GCLMENSG00000023909.52717.232402085.721700.381503.614102.19350K562ABCF1
GCLMENSG00000023909.53953.855603248.917100.283202.904802.32450K562AGGF1
GCLMENSG00000023909.53738.156602909.488000.361503.501302.85700K562AQR
GCLMENSG00000023909.52867.699103547.28570-0.306802.355501.51960K562ATP5C1
GCLMENSG00000023909.51956.110901239.863000.657708.021106.50070K562BOP1
GCLMENSG00000023909.52132.881501548.228700.462106.164103.91440K562CEBPZ
GCLMENSG00000023909.52943.836502094.628200.490902.629301.60020K562CNOT7
GCLMENSG00000023909.56063.231103373.953800.8455024.5395022.07550K562CELF1
GCLMENSG00000023909.52299.280201779.533200.369605.231503.52620K562DDX21
GCLMENSG00000023909.52974.168702376.415700.323604.992204.15300K562DDX47
GCLMENSG00000023909.52013.357901393.192300.531104.291102.66360K562EEF2
GCLMENSG00000023909.51550.535601815.04930-0.227202.208301.55500K562EIF2S2
GCLMENSG00000023909.52127.533801441.468100.561505.035903.58950K562EIF3D
GCLMENSG00000023909.51464.656801753.28470-0.259502.145701.43870K562EIF3G
GCLMENSG00000023909.53820.329302743.901300.477409.865008.12980K562EIF4G2
GCLMENSG00000023909.52303.116001594.407900.530504.050102.03520K562ESF1
GCLMENSG00000023909.52091.075601499.419100.479705.330304.12680K562FIP1L1
GCLMENSG00000023909.51372.444401078.391600.347802.337401.31290K562FKBP4
GCLMENSG00000023909.52103.644901341.436300.649004.129303.08100K562FMR1
GCLMENSG00000023909.51824.484801137.049300.682107.378505.81120K562FTO
GCLMENSG00000023909.53000.960502046.446900.552203.496102.68250K562G3BP2
GCLMENSG00000023909.52516.807901459.532900.7860011.400309.24320K562GLRX3
GCLMENSG00000023909.51988.066601258.553400.659508.684707.27120K562GPKOW
GCLMENSG00000023909.52433.407201560.184400.641207.814106.09350K562HNRNPA1
GCLMENSG00000023909.52460.527402032.793800.275402.097401.40160K562HSPD1
GCLMENSG00000023909.53124.432401912.133800.708304.542702.68740K562ILF2
GCLMENSG00000023909.5938.63650621.451800.594804.996003.00370K562ILF3
GCLMENSG00000023909.51706.840601074.799900.667205.728504.32540K562KRR1
GCLMENSG00000023909.5767.968101107.64350-0.528405.502203.24660K562LSM11
GCLMENSG00000023909.51600.854302325.81620-0.538903.342102.31610K562MATR3
GCLMENSG00000023909.52311.818101534.506300.591207.357906.09480K562MTPAP
GCLMENSG00000023909.52319.411501704.986700.4439011.6564010.26880K562NSUN2
GCLMENSG00000023909.5889.147901223.10150-0.460003.083701.55640K562NUSAP1
GCLMENSG00000023909.52845.099602012.326200.499502.511401.34880K562PABPC1
GCLMENSG00000023909.5726.756701113.84600-0.616006.321204.86590K562PSIP1
GCLMENSG00000023909.55095.893102993.787400.7673014.6397012.74560K562PUF60
GCLMENSG00000023909.55308.680603184.476400.737205.497403.95080K562PUM1
GCLMENSG00000023909.53868.795203120.040200.310204.485103.25600K562PUM2
GCLMENSG00000023909.51399.139302359.67380-0.7540010.104808.07180K562RPS3
GCLMENSG00000023909.52066.760701339.496300.625605.234503.40420K562RRP9
GCLMENSG00000023909.5977.610801307.63260-0.419603.980502.67210K562SAFB
GCLMENSG00000023909.52448.693301121.047001.1271013.1366010.20850K562SERBP1
GCLMENSG00000023909.52394.099001682.368300.508903.444402.54020K562SF3A3
GCLMENSG00000023909.51820.340101197.140600.604505.821004.37730K562SF3B1
GCLMENSG00000023909.5925.92560655.355400.498503.207901.84050K562SLBP
GCLMENSG00000023909.5639.15910963.31800-0.591805.703004.08030K562SRFBP1
GCLMENSG00000023909.51165.472502219.31390-0.929207.141806.01350K562SRSF1
GCLMENSG00000023909.51688.834702278.03330-0.431805.153203.64050K562SRSF4
GCLMENSG00000023909.52030.109001588.126900.354104.625003.09370K562SRSF7
GCLMENSG00000023909.52457.069701808.484100.442106.717504.59790K562SSB
GCLMENSG00000023909.52720.785301967.227700.467805.119303.23610K562SSRP1
GCLMENSG00000023909.52948.313001799.216700.712409.466807.07950K562STAU1
GCLMENSG00000023909.53450.243002612.101200.401405.927503.83420K562SUCLG1
GCLMENSG00000023909.52327.555401753.622900.408403.832402.12150K562TRIP6
GCLMENSG00000023909.52420.526901546.906800.6458010.830209.04920K562WDR3
GCLMENSG00000023909.52215.221501608.592600.4616010.214408.70620K562WDR43
GCLMENSG00000023909.54571.848603447.859200.407004.935603.20810K562WRN
GCLMENSG00000023909.54917.213403277.314100.585209.295407.59380K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for GCLM is not available on ENCORE database.





6 RBPs can affect the splicing of GCLM :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEGCLMENSG00000023909.5chr1-943700789437014494367140943672259437459394374966-0.239000.000380.00957excludedK562SF3B4
SEGCLMENSG00000023909.5chr1-943700789437014494367140943672259437459394374966-0.221000.000060.00336excludedK562AKAP8L
SEGCLMENSG00000023909.5chr1-943621739436240994360169943602849436339494363454-0.052000.000000.00004excludedK562AQR
SEGCLMENSG00000023909.5chr1-943700789437014494367140943672259437459394374966-0.174000.000710.01284excludedK562PUS1
SEGCLMENSG00000023909.5chr1-9435944494359646943507609435471594360169943602840.075000.000000.00000includedK562HNRNPU
SEGCLMENSG00000023909.5chr1-943700789437014494367140943672259437459394374966-0.290000.000000.00010excludedK562RBM15
A3SSGCLMENSG00000023909.5chr1-9437007894370168943700789437014494374593943749660.096000.017580.08545longerK562AQR
MXEGCLMENSG00000023909.5chr1-9436339494363454943671409436722594360169943602849437007894370144-0.105000.000000.000032includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for GCLM is not avaliable on ENCORE database.