GPKOW

General Information

Gene Name       : GPKOW
Gene ID             : ENSG00000068394.10
Essential Gene : Yes

Functions

Localization(RBPImage: GPKOW)

Domains (AlphaFold: GPKOW)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878GPKOWENSG00000068394.108.7913.9911.39ENCSR000AEF
HepG2GPKOWENSG00000068394.1017.4513.4615.46ENCSR985KAT
K562GPKOWENSG00000068394.1022.6321.1321.88ENCSR000AEO

Assays

3 Released experiments are available on ENCORE database.

Assay TypeExp_NameENCODE IDTarget labelBiosampleStatusLinked AntibodyControlsMethodNote
eCLIPeCLIP: 450ENCSR647CLFGPKOWK562ReleasedENCAB445RKHENCSR393STP  
knockdown followed by RNA-seq GPKOW-BGKLV36-K562ENCSR967QNTGPKOWK562ReleasedENCSR424QCW   shRNAKD% = 50.0,57.0
knockdown followed by RNA-seq GPKOW-BGHLV35-HepG2ENCSR968YWYGPKOWHepG2ReleasedENCSR264TUE   shRNAKD% = 62.3,67.3






  eCLIP  
  RBP    Exp_UID    Cell_Line    ENCODE_ACCESSION    Control_ENCODE_ACCESSION    ENCODE_Antibody_ID    Antibody    Lot_num    Status    Project  
GPKOW450K562ENCSR647CLFENCSR393STPENCAB445RKHGTX11771640289ReleasedENCODE3


  Antibody Validation  
  GeneName    Antibody_DCC_ID    Product_ID    Lot_ID    Phosphate    HepG2 Primary Validation    K562 Primary Validation    HepG2 Secondary Validation    K562 Secondary Validation  
GPKOWENCAB445RKHGTX11771640289Released, ENCODE3BGHLV35-21, Released, ENCODE3BGKLV36-27, Released, ENCODE3


  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
GPKOWK562shRNAENCSR967QNTENCSR424QCWGPKOW_BGKLV36-27,GPKOW_BGKLV36-28NT_BGKLV36-1,NT_BGKLV36-250.0,57.0ReleasedENCODE3
GPKOWHepG2shRNAENCSR968YWYENCSR264TUEGPKOW_BGHLV35-21,GPKOW_BGHLV35-22NT_BGHLV35-1,NT_BGHLV35-262.3,67.3ReleasedENCODE3


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  
    GPKOW: Click to RBP Image Database
  • Nuclei
  • Nucleoplasm
  • Mutually Exclusive from Nucleolus
  • Speckles
  • Nuclear release mitosis












    • RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela
    GPKOWProduct_ID: GTX117716
    Lot_ID: 40289
    Source: GeneTex
    Target Name: GPKOW-human    		 GPKOW-HEPG2.png<br>Caption: Western blot following shRNA against GPKOW in HepG2 whole cell lysate using GPKOW specific antibody. Lane 1 is a ladder, lane 2 is HepG2 non-targeting control knockdown, lane 3 and 4 are two different shRNAs against GPKOW.GPKOW protein appears as the green arrow, GAPDH serves as a control and appears in red arrow.
    		 K562_Genetex_GTX117716_40289_GPKOW.png<br>Caption: IP-Western Blot analysis of K562 whole cell lysate using GPKOW specific antibody. Lane 1 is 1% of twenty million whole cell lysate input and lane 2 is 10% of IP enrichment using rabbit normal IgG (lanes under 'IgG'). Lane 3 is 1% of twenty million whole cell lysate input and lane 4 is 10% IP enrichment using rabbit polyclonal anti-GPKOW antibody (lanes under 'GPKOW').
    		 GPKOW-K562.png<br>Caption: Western blot following shRNA against GPKOW in K562 whole cell lysate using GPKOW specific antibody. Lane 1 is a ladder, lane 2 is K562 non-targeting control knockdown, lane 3 and 4 are two different shRNA against GPKOW.GPKOW protein appears as the green arrow, GAPDH serves as a control and appears in red arrow.








    RNA Targets
    • GPKOW protein binds to 1,128 RNA regions.  





    Proteins bound to RNA
    • GPKOW RNA is bound by 5 proteins.  






    GPKOW protein has 1,128 RNA targets:

    Only display 100 entries as example. Please click "View All" button to see all 1,128 entries.     

    RBP Chr Start End Strand log2(fold change) -log(p-value) Cell Line Matched Gene Matched Area
    GPKOWchr174414405444144131-4.594175.44803K562KANSL13'-UTR,CDS,intron-Distal,intron-Proximal
    GPKOWchr1100177607100177743-3.714327.58296K562FRRS1CDS,intron-Distal,intron-Proximal
    GPKOWchr116236810962368176-3.073265.48082K562MTA25'-UTR,CDS,intron-Distal,intron-Proximal
    GPKOWchr765027676502831-3.880616.80028K562KDELR2, DAGLB3'-UTR,CDS,intron-Distal
    GPKOWchr156395208263952198-3.472206.23623K562HERC1CDS,intron-Distal,intron-Proximal
    GPKOWchr1145441170145441220+4.20310400.00000K562TXNIP3'-UTR,CDS,intron-Proximal
    GPKOWchr1622786302278722+5.336884.39274K562E4F1intron-Distal
    GPKOWchr6126332165126332233+4.253328.93479K562TRMT11intron-Distal
    GPKOWchr5137897472137897495-3.564726.15923K562HSPA9CDS,intron-Distal,intron-Proximal
    GPKOWchrX135958622135958667-3.410779.49147K562RBMX3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal
    GPKOWchr1162762623162762702+3.561903.43713K562HSD17B73'-UTR,CDS,intron-Proximal
    GPKOWchr2152267081152267128+4.544407.36651K562RIF1intron-Distal,intron-Proximal
    GPKOWchr34267505142675134+4.557179.59259K562NKTR3'-UTR,CDS,intron-Proximal
    GPKOWchr165326288853262962+3.016533.40130K562CHD9CDS,intron-Proximal
    GPKOWchr12338153223381587+3.857208.69282K562KDM1ACDS,intron-Proximal
    GPKOWchr16589102765891143+3.448085.20150K562LEPR, LEPROT5'-UTR,CDS,intron-Proximal
    GPKOWchr73063965030639697+3.1655410.44194K562GARS3'-UTR,CDS,intron-Proximal
    GPKOWchr2242610803242610866+3.244674.59403K562ATG4B3'-UTR,CDS,intron-Proximal
    GPKOWchr185527888755278932-4.044406.11810K562NARSCDS,intron-Distal
    GPKOWchr2192546701192546789+3.859424.89564K562NABP1CDS,intron-Proximal
    GPKOWchr213499427834994367-5.310655.00483K562CRYZL1, AP000304.125'-UTR,CDS,intron-Distal,intron-Proximal
    GPKOWchr116173232761732378-3.7345242.61177K562FTH13'-UTR,CDS,intron-Distal,intron-Proximal
    GPKOWchr71097767410977746-5.783428.16831K562NDUFA4CDS,intron-Distal,intron-Proximal
    GPKOWchr2039147853914896-5.1379010.01073K562RNF24CDS,intron-Distal
    GPKOWchr116371439363714472+5.736878.16831K562NAA403'-UTR,CDS,intron-Distal,intron-Proximal
    GPKOWchr1100525429100525476+3.386653.95214K562HIAT1CDS,intron-Proximal
    GPKOWchr127644695676446975-4.103138.35991K562NAP1L1intron-Distal,intron-Proximal
    GPKOWchr33805980038059870-4.368384.81549K562PLCD1intron-Distal
    GPKOWchr97578393775783984+4.4848511.79989K562ANXA1CDS,intron-Proximal
    GPKOWchr1219482531948280-4.336884.19050K562CACNA2D4intron-Distal
    GPKOWchr7151168434151168475-5.129363.78571K562RHEBintron-Distal,intron-Proximal
    GPKOWchr1223957582223957665+4.0330417.14795K562CAPN2CDS,intron-Proximal
    GPKOWchr48382085283820912-3.018166.72589K562SEC31A, THAP9-AS15'-UTR,intron-Distal,intron-Proximal
    GPKOWchr3195785115195785164-3.184459.40142K562TFRC3'-UTR,CDS,intron-Distal,intron-Proximal
    GPKOWchr173546853535468594-4.247884.81549K562ACACA3'-UTR,CDS,intron-Distal,intron-Proximal
    GPKOWchr13582503535825054+5.173099.13075K562ZMYM4CDS,intron-Proximal
    GPKOWchr11107968339107968393+5.103135.00483K562CUL5CDS,intron-Proximal
    GPKOWchr1268791086879174+3.6608713.01794K562PTMSCDS,intron-Proximal
    GPKOWchr13582505435825081+5.971618.74439K562ZMYM4intron-Proximal
    GPKOWchr1145439591145439628+3.2054226.76718K562TXNIPCDS,intron-Distal,intron-Proximal
    GPKOWchr32001705920017135+3.962654.39974K562RAB5A3'-UTR,CDS,intron-Proximal
    GPKOWchr64374589443745982+3.59820400.00000K562VEGFAintron-Distal
    GPKOWchr72303063823030703-5.162924.80701K562FAM126ACDS,intron-Distal,intron-Proximal
    GPKOWchr58669025786690308-3.033045.12804K562CCNH3'-UTR,CDS,intron-Distal,intron-Proximal
    GPKOWchr191619979516199886+3.6851110.25249K562TPM4CDS,intron-Proximal
    GPKOWchr79900109899001161-3.098665.12804K562PDAP15'-UTR,CDS,intron-Distal,intron-Proximal
    GPKOWchr191125854311258587-3.981634.95436K562SPC243'-UTR,CDS,intron-Distal,intron-Proximal
    GPKOWchr2153547461153547496-3.801684.89564K562PRPF40A3'-UTR,CDS,intron-Distal,intron-Proximal
    GPKOWchr1174212379174212424+4.386653.78820K562RABGAP1Lintron-Distal
    GPKOWchr8126017910126017971+4.662925.52568K562SQLECDS,intron-Proximal
    GPKOWchr176249688162496910-3.6239713.05460K562DDX53'-UTR,CDS,intron-Distal,intron-Proximal
    GPKOWchr156970969269709761+3.322424.69615K562KIF23CDS,intron-Proximal
    GPKOWchr125619749656197523-4.433203.78820K562RP11-762I7.5, SARNP3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal
    GPKOWchr3160967257160967383+3.079296.02757K562NMD3CDS,intron-Proximal
    GPKOWchrX4119836941198408+3.184454.20013K562DDX3Xintron-Distal,intron-Proximal
    GPKOWchr76445040664450458-3.738924.89564K562ZNF1175'-UTR,intron-Distal
    GPKOWchr203300031033000364+3.870444.95436K562ITCH5'-UTR,CDS,intron-Proximal
    GPKOWchr34373312943733228+3.032745.31767K562ABHD5intron-Distal
    GPKOWchr1224492773224492875-3.687105.55543K562NVL3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal
    GPKOWchr5145616830145616883+4.706655.52568K562RBM27CDS,intron-Proximal
    GPKOWchr2160619363160619423+3.391149.57460K562MARCH7CDS,intron-Proximal
    GPKOWchr173068784330687929+3.625537.07785K562ZNF207CDS,intron-Proximal
    GPKOWchr166685135666851398-5.179135.00483K562NAE13'-UTR,CDS,intron-Distal,intron-Proximal
    GPKOWchr53239524432395279-3.990946.08476K562ZFRCDS,intron-Distal,intron-Proximal
    GPKOWchr57463837674638436+3.4829710.18067K562HMGCR3'-UTR,5'-UTR,CDS,intron-Proximal
    GPKOWchr119346623293466335-4.4262327.99170K562TAF1D3'-UTR,intron-Distal,intron-Proximal
    GPKOWchr4140297608140297666+3.7057810.87543K562NAA15CDS,intron-Proximal
    GPKOWchr1145440150145440153+4.4920518.92122K562TXNIPintron-Distal,intron-Proximal
    GPKOWchr6160164681160164744+3.840096.66119K562WTAPCDS,intron-Proximal
    GPKOWchr14445111644451199+5.103135.00483K562B4GALT2CDS,intron-Proximal
    GPKOWchr5145529224145529280-3.003598.48950K562LARSCDS,intron-Distal,intron-Proximal
    GPKOWchr4164440475164440530+4.140725.51636K562TMA163'-UTR,CDS,intron-Distal,intron-Proximal
    GPKOWchr2178080235178080297+3.373778.80847K562HNRNPA3CDS,intron-Proximal
    GPKOWchr171597671815976805-3.518165.01263K562NCOR1CDS,intron-Distal,intron-Proximal
    GPKOWchr7104716466104716548+3.4175613.06521K562KMT2E3'-UTR,CDS,intron-Proximal
    GPKOWchr127202564472025725-3.435707.59237K562ZFC3H1CDS,intron-Distal,intron-Proximal
    GPKOWchr64359461743594726-3.4249615.83209K562GTPBP25'-UTR,CDS,intron-Distal,intron-Proximal
    GPKOWchr29756051397560571-4.0254914.41552K562FAM178Bintron-Distal
    GPKOWchr1299071289907195-5.4073911.34232K562CD693'-UTR,CDS,intron-Distal,intron-Proximal
    GPKOWchr63693766536937731-3.218138.23906K562MTCH1CDS,intron-Distal,intron-Proximal
    GPKOWchr1244849909244849991+5.018164.80701K562DESI2CDS,intron-Proximal
    GPKOWchr1109824178109824241-4.255137.23765K562PSRC1intron-Distal,intron-Proximal
    GPKOWchr12710077527100892+3.013144.61019K562ARID1ACDS,intron-Distal,intron-Proximal
    GPKOWchr195184240051842500-3.735246.70001K562VSIG10Lintron-Distal,intron-Proximal
    GPKOWchr175791709957917164+3.197399.54630K562VMP13'-UTR,CDS,intron-Proximal
    GPKOWchr1130237183023835-3.098429.54630K562CARS3'-UTR,CDS,intron-Distal,intron-Proximal
    GPKOWchr1137818343781870-3.513145.01422K562NUP98CDS,intron-Distal,intron-Proximal
    GPKOWchr1109235496109235576+3.633474.57930K562PRPF38Bintron-Proximal
    GPKOWchrX4492055444920593+3.461495.09803K562KDM6ACDS,intron-Proximal
    GPKOWchr4166261533166261564+4.1191121.59709K562MSMO13'-UTR,intron-Proximal
    GPKOWchr5158586025158586052-5.187104.14692K562RNF145CDS,intron-Distal,intron-Proximal
    GPKOWchr172563560925635665+3.6931018.13111K562WSB13'-UTR,intron-Distal
    GPKOWchr7150779721150779786-3.384724.59403K562TMUB15'-UTR,intron-Distal,intron-Proximal
    GPKOWchr155892551958925587-3.753975.72758K562ADAM103'-UTR,CDS,intron-Distal,intron-Proximal
    GPKOWchr12104713222104713273+5.444396.14157K562TXNRD1CDS,intron-Distal,intron-Proximal
    GPKOWchr26152218361522212-5.455406.81439K562USP34intron-Distal,intron-Proximal
    GPKOWchr1150198945150199072-3.4702720.36579K562ANP32E3'-UTR,CDS,intron-Distal,intron-Proximal
    GPKOWchr222011447620114496+3.029524.82363K562RANBP13'-UTR,CDS,intron-Proximal
    GPKOWchr7131099390131099448+3.191214.59403K562MKLN13'-UTR,CDS,intron-Proximal
    GPKOWchr64353642843536509-3.057176.19305K562XPO5CDS,intron-Distal,intron-Proximal




    5 proteins are bound to GPKOW RNA:

    Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
    chrX4897043148970455-3'-UTR,intron-Distal4.746495.20653K562LIN28B
    chrX4897044848970556-3'-UTR,intron-Distal4.003493.45275HepG2LARP4
    chrX4897045548970504-3'-UTR,intron-Distal5.272898.09274K562LIN28B
    chrX4897981348979898-CDS,intron-Distal6.6572717.53326K562AQR
    chrX4897408248974109-CDS,intron-Distal3.198743.24816K562YBX3
    chrX4897908148979177-CDS,intron-Distal,intron-Proximal4.7076012.35151K562AQR
    chrX4897389748973952-CDS,intron-Distal,intron-Proximal4.672064.86944K562AQR
    chrX4897324148973379-intron-Distal,intron-Proximal6.9766819.59836K562EFTUD2
    ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




    No autoregularoty interactions between protein GPKOW and its RNA.



    Diffrential Expression
    • 12,245 differentially expressed genes after Knockdown/Knockout GPKOW protein.  





    • 39 RBPs can affect the levels of GPKOW.  







    12,245 differentially expressed genes after Knockdown/Knockout GPKOW protein :

    Only display 100 entries as example. Please click "View All" button to see all 12,245 entries.     

    Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
    DPM1ENSG00000000419.81618.162802279.18390-0.494204.315103.52680HepG2GPKOW
    SCYL3ENSG00000000457.9231.21140136.872000.756303.414702.70950HepG2GPKOW
    C1orf112ENSG00000000460.12126.43580243.83080-0.947505.017804.17200HepG2GPKOW
    FUCA2ENSG00000001036.91917.078303151.20460-0.717008.817607.71840HepG2GPKOW
    NFYAENSG00000001167.101278.630502010.31120-0.652806.783705.80840HepG2GPKOW
    NIPAL3ENSG00000001461.12326.53270192.976700.758704.180803.40550HepG2GPKOW
    LAS1LENSG00000001497.12600.77380770.54700-0.359101.880401.34530HepG2GPKOW
    ENPP4ENSG00000001561.638.380209.656701.990703.372102.66990HepG2GPKOW
    CYP51A1ENSG00000001630.1111396.750404539.941501.3278031.2095029.34150HepG2GPKOW
    MAD1L1ENSG00000002822.11441.17150615.45360-0.480302.784502.14160HepG2GPKOW
    LASP1ENSG00000002834.1311775.936907354.666600.679009.073407.95560HepG2GPKOW
    M6PRENSG00000003056.31251.751201968.12570-0.652906.794605.81850HepG2GPKOW
    KLHL13ENSG00000003096.9100.423409.599003.3870014.8617013.49450HepG2GPKOW
    ALS2ENSG00000003393.101529.090501212.971600.334002.093701.53270HepG2GPKOW
    CASP10ENSG00000003400.10572.28740335.299200.771205.791704.88940HepG2GPKOW
    CFLARENSG00000003402.152425.599501839.581300.398903.077902.40720HepG2GPKOW
    NDUFAF7ENSG00000003509.11385.66250654.82990-0.763806.104705.17950HepG2GPKOW
    SLC7A2ENSG00000003989.121716.521102277.32320-0.407902.326801.73700HepG2GPKOW
    SARM1ENSG00000004139.947.4005014.964901.663202.402101.80170HepG2GPKOW
    POLDIP2ENSG00000004142.7858.332201478.44560-0.784508.766607.66950HepG2GPKOW
    PLXND1ENSG00000004399.81725.680302485.80550-0.526504.892404.05720HepG2GPKOW
    AK2ENSG00000004455.121847.315702341.26340-0.341902.421701.81880HepG2GPKOW
    KDM1AENSG00000004487.111973.949402917.69820-0.563705.734404.83570HepG2GPKOW
    RBM6ENSG00000004534.104682.098703602.891200.377902.997802.33500HepG2GPKOW
    CAMKK1ENSG00000004660.1062.0990029.967001.051102.017901.46580HepG2GPKOW
    RECQLENSG00000004700.11604.28200962.08580-0.670905.746404.84620HepG2GPKOW
    ARHGAP33ENSG00000004777.14319.07470196.334400.700503.527502.81330HepG2GPKOW
    NDUFAB1ENSG00000004779.5645.49580897.24590-0.475103.225402.53890HepG2GPKOW
    SLC25A13ENSG00000004864.9940.498601483.10550-0.657106.502805.54970HepG2GPKOW
    ST7ENSG00000004866.14387.60840586.71820-0.598103.849403.10560HepG2GPKOW
    CDC27ENSG00000004897.73590.400205081.18410-0.501004.933604.09410HepG2GPKOW
    SLC25A5ENSG00000005022.52010.922602571.17240-0.354602.536801.92140HepG2GPKOW
    POLR2JENSG00000005075.111117.013301537.20700-0.460703.477902.76630HepG2GPKOW
    DHX33ENSG00000005100.8772.688201522.13960-0.9781013.0340011.74190HepG2GPKOW
    LIG3ENSG00000005156.7644.931701140.71780-0.822708.742507.64740HepG2GPKOW
    RPAP3ENSG00000005175.5909.142401272.79410-0.485403.611402.88850HepG2GPKOW
    ACSM3ENSG00000005187.74414.09130547.972403.0098049.4213047.13310HepG2GPKOW
    AC004381.6ENSG00000005189.15123.70820182.63820-0.562001.852401.32160HepG2GPKOW
    SPPL2BENSG00000005206.12616.39070343.487200.843506.231305.29720HepG2GPKOW
    FAM214BENSG00000005238.15449.64080188.994801.250302.565801.94650HepG2GPKOW
    CROTENSG00000005469.7505.46450234.676501.1068010.136108.96490HepG2GPKOW
    ABCB4ENSG00000005471.11616.45190445.178700.469502.659202.02950HepG2GPKOW
    MYCBP2ENSG00000005810.131106.126901702.32880-0.622006.094205.16960HepG2GPKOW
    ITGALENSG00000005844.13192.5645038.616402.3180016.0445014.62520HepG2GPKOW
    PDK2ENSG00000005882.71388.51370843.472300.719007.457006.43600HepG2GPKOW
    ZFXENSG00000005889.112587.35770659.771701.9713051.6759049.33880HepG2GPKOW
    ITGA2BENSG00000005961.1331.040208.917201.799402.407301.80600HepG2GPKOW
    ASB4ENSG00000005981.85.74060283.41090-5.6256039.5191037.43910HepG2GPKOW
    CRLF1ENSG00000006016.6515.743103080.52340-2.5785057.3285054.87300HepG2GPKOW
    TMEM98ENSG00000006042.7520.652801062.78280-1.0295012.6292011.35570HepG2GPKOW
    YBX2ENSG00000006047.876.760409.147903.0688010.476309.28620HepG2GPKOW
    MAP3K14ENSG00000006062.9148.0906088.819400.737401.859701.32800HepG2GPKOW
    TMEM132AENSG00000006118.10338.05100501.80250-0.569903.355602.65510HepG2GPKOW
    AP2B1ENSG00000006125.122398.271903070.87820-0.356702.640802.01270HepG2GPKOW
    CX3CL1ENSG00000006210.67585.121801871.378502.0190010.851409.64090HepG2GPKOW
    SPATA20ENSG00000006282.151989.593701343.256300.566604.832704.00190HepG2GPKOW
    TNFRSF12AENSG00000006327.91104.94400417.803001.4030018.8872017.36940HepG2GPKOW
    DLX6ENSG00000006377.9122.20170198.40030-0.699102.694902.06150HepG2GPKOW
    MAP3K9ENSG00000006432.11426.41060712.95310-0.741606.022205.10360HepG2GPKOW
    BAIAP2L1ENSG00000006453.9639.26550981.15170-0.618104.923704.08540HepG2GPKOW
    JHDM1DENSG00000006459.6428.481201309.86630-1.6121029.6019027.77020HepG2GPKOW
    AGKENSG00000006530.11516.62980671.20590-0.377601.957901.41350HepG2GPKOW
    PHTF2ENSG00000006576.12248.84860502.03700-1.012508.478307.39910HepG2GPKOW
    GGCTENSG00000006625.13564.47620805.39810-0.512803.458902.74910HepG2GPKOW
    DBF4ENSG00000006634.3458.553901096.26010-1.2574017.7024016.22440HepG2GPKOW
    ARSDENSG00000006756.11365.47160222.502900.715802.355301.76110HepG2GPKOW
    UPP2ENSG00000007001.817.581401.468703.581403.196902.51350HepG2GPKOW
    MARK4ENSG00000007047.10547.75090706.27100-0.366701.894201.35780HepG2GPKOW
    CCDC124ENSG00000007080.6297.45820507.18510-0.769803.972103.21650HepG2GPKOW
    PAFAH1B1ENSG00000007168.81138.393601778.37210-0.643606.454705.50440HepG2GPKOW
    KIAA0100ENSG00000007202.102185.560303900.09430-0.8355012.0068010.75550HepG2GPKOW
    PAX6ENSG00000007372.169.7331082.84980-3.089505.277504.41130HepG2GPKOW
    RHBDF1ENSG00000007384.11430.79990230.785700.900406.441605.49280HepG2GPKOW
    LUC7LENSG00000007392.12983.187201286.18530-0.387602.493901.88320HepG2GPKOW
    BAIAP3ENSG00000007516.9198.6713070.859401.487304.796203.96860HepG2GPKOW
    PIGQENSG00000007541.10293.48420192.651200.607202.804502.15980HepG2GPKOW
    E2F2ENSG00000007968.684.98690209.78330-1.303607.412306.39500HepG2GPKOW
    JARID2ENSG00000008083.9965.723901327.80690-0.459403.322802.62610HepG2GPKOW
    CDKL5ENSG00000008086.6428.37620204.641601.065707.648306.61780HepG2GPKOW
    SYPL1ENSG00000008282.3474.566401143.72690-1.2691017.4423015.97250HepG2GPKOW
    CYB561ENSG00000008283.1197.8259057.641300.763001.857301.32570HepG2GPKOW
    SPAG9ENSG00000008294.161684.360402387.76390-0.503504.502803.69900HepG2GPKOW
    CELSR3ENSG00000008300.101343.58830723.304400.8933010.578509.38380HepG2GPKOW
    AASSENSG00000008311.10462.55290708.21770-0.614604.430503.63230HepG2GPKOW
    PLEKHG6ENSG00000008323.11857.43470132.713302.6916020.2953018.73510HepG2GPKOW
    MGST1ENSG00000008394.81861.871002403.56320-0.368402.688902.05650HepG2GPKOW
    CRY1ENSG00000008405.7166.61980405.06680-1.2816011.145309.92730HepG2GPKOW
    NFIXENSG00000008441.12721.065701129.93210-0.648005.736704.83770HepG2GPKOW
    ST3GAL1ENSG00000008513.101805.19120963.136700.9062011.8910010.64360HepG2GPKOW
    IL32ENSG00000008517.128630.764802569.230701.7481051.2422048.91300HepG2GPKOW
    PKD1ENSG00000008710.131256.09140556.902501.173304.488503.68620HepG2GPKOW
    MAPK8IP2ENSG00000008735.10238.1677095.192701.323002.490001.87950HepG2GPKOW
    RHOBTB2ENSG00000008853.121139.21360448.970901.3432020.5394018.96700HepG2GPKOW
    RPS20ENSG00000008988.52634.186404475.07350-0.764606.070405.14770HepG2GPKOW
    CSDE1ENSG00000009307.118868.5302011791.55390-0.411003.705302.97380HepG2GPKOW
    MASP2ENSG00000009724.12798.06220235.401901.7613027.2678025.49430HepG2GPKOW
    IYDENSG00000009765.1062.377800.451107.111308.335007.26740HepG2GPKOW
    POMT2ENSG00000009830.7635.73220446.966500.508203.130302.45420HepG2GPKOW
    MLXIPLENSG00000009950.1113182.496404425.777701.5745043.1571041.01560HepG2GPKOW
    BAZ1BENSG00000009954.63599.737505245.68820-0.543205.743604.84400HepG2GPKOW
    Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

    *: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
    **: "-log(0)" was displayed as "99999.99999".





    39 RBPs can affect the gene expression of GPKOW :

    Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
    GPKOWENSG00000068394.9374.77200613.50410-0.711104.717403.42920HepG2CCAR1
    GPKOWENSG00000068394.9583.92390453.347600.365102.974002.31140HepG2CELF1
    GPKOWENSG00000068394.9235.55150301.57370-0.356502.024801.30110HepG2DDX19B
    GPKOWENSG00000068394.9165.36520294.96740-0.834902.352201.51610HepG2DDX24
    GPKOWENSG00000068394.9345.71000460.65750-0.414102.082201.36820HepG2EIF4G2
    GPKOWENSG00000068394.9378.87540558.65310-0.560205.770404.95500HepG2ETF1
    GPKOWENSG00000068394.9322.02120484.71080-0.590002.467101.62800HepG2G3BP2
    GPKOWENSG00000068394.9101.19850473.51430-2.2262029.0615027.25160HepG2GPKOW
    GPKOWENSG00000068394.9444.45970647.48450-0.542803.116802.23240HepG2LARP4
    GPKOWENSG00000068394.9345.96630495.01940-0.516902.153201.59260HepG2MATR3
    GPKOWENSG00000068394.9341.66730431.91210-0.338102.002301.47300HepG2PCBP1
    GPKOWENSG00000068394.9215.32520333.93970-0.633104.917103.91560HepG2PRPF4
    GPKOWENSG00000068394.9314.73120439.50840-0.481803.225702.64430HepG2PTBP1
    GPKOWENSG00000068394.9322.56720461.36240-0.516303.204002.56880HepG2PUF60
    GPKOWENSG00000068394.9612.45430428.690900.514604.300203.25960HepG2RBM15
    GPKOWENSG00000068394.9371.85370466.92260-0.328401.797601.35650HepG2RBM22
    GPKOWENSG00000068394.9282.51010431.97470-0.612604.316903.48960HepG2RBM25
    GPKOWENSG00000068394.9390.35970489.11260-0.325401.858201.39550HepG2NELFE
    GPKOWENSG00000068394.9259.34820402.46290-0.634003.322402.58140HepG2SF3A3
    GPKOWENSG00000068394.9226.38090447.26500-0.982408.953507.75280HepG2SF3B1
    GPKOWENSG00000068394.9278.40440457.54610-0.716706.560105.71210HepG2SF3B4
    GPKOWENSG00000068394.9358.65240477.59490-0.413202.647802.18230HepG2SRSF1
    GPKOWENSG00000068394.9276.72180356.11280-0.363901.920801.32990HepG2SRSF7
    GPKOWENSG00000068394.9358.00940457.84650-0.354902.507502.01410HepG2SSB
    GPKOWENSG00000068394.9241.74540429.32490-0.828607.911807.04240HepG2TAF15
    GPKOWENSG00000068394.9268.23960440.50450-0.715605.128804.18590HepG2TARDBP
    GPKOWENSG00000068394.9238.54000356.92300-0.581404.563303.70310HepG2UPF1
    GPKOWENSG00000068394.9572.54540392.547100.544406.132805.40200HepG2ZNF622
    GPKOWENSG00000068394.91322.686801055.154800.325902.504501.57800K562AKAP8
    GPKOWENSG00000068394.9852.462101075.26490-0.335003.318702.34950K562DKC1
    GPKOWENSG00000068394.9663.66510464.134100.515802.713901.44820K562EEF2
    GPKOWENSG00000068394.9821.08520585.223300.488404.535203.64180K562EIF2S2
    GPKOWENSG00000068394.9710.47220562.242200.337502.116901.39470K562EIF4A3
    GPKOWENSG00000068394.9926.864101089.47510-0.233202.169101.33260K562EIF4G2
    GPKOWENSG00000068394.9108.60730280.04180-1.366509.717208.23350K562G3BP2
    GPKOWENSG00000068394.9202.09630591.30930-1.5489023.7010021.21690K562GPKOW
    GPKOWENSG00000068394.9892.42560707.546500.334802.049901.36090K562HSPD1
    GPKOWENSG00000068394.9724.07970463.527100.643404.634203.16580K562IGF2BP2
    GPKOWENSG00000068394.9394.79650291.371500.438102.771301.91560K562SF3B4
    GPKOWENSG00000068394.9720.17220874.72210-0.280502.544301.64140K562SRPK2
    GPKOWENSG00000068394.9639.39200463.715100.463403.553502.75950K562SRSF1
    GPKOWENSG00000068394.9635.90510438.042700.537603.600502.37130K562SRSF5
    GPKOWENSG00000068394.9673.16440452.642200.572504.328503.27060K562TIA1
    GPKOWENSG00000068394.9651.27060444.379900.551404.340602.91980K562TRA2A
    Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

    *: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
    **: "-log(0)" was displayed as "99999.99999".





    285 alternative splicing events after Knockdown/Knockout GPKOW protein :

    Only display 100 entries as example. Please click "View All" button to see all 285 entries.     

    Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
    SESNRNP70ENSG00000104852.10chr19+4960537049606844496046464960472849607890496079920.174000.000000.00000includedK562GPKOW
    SEDEAF1ENSG00000177030.12chr11-6511616514076442326446546539616540510.393000.000350.07057includedK562GPKOW
    SESTXBP2ENSG00000076944.10chr19+7712239771239777120477712133771261077127590.131000.000000.00177includedK562GPKOW
    SELRPPRCENSG00000138095.14chr2-4412355744123683441216834412176844123772441238470.090000.000160.04411includedK562GPKOW
    SEGOLGA8AENSG00000175265.13chr15-3484509534845246348433383484347734845945348461570.218000.000660.09702includedK562GPKOW
    SETSEN15ENSG00000198860.7chr1+1840397491840398661840238611840239971840412901840414440.197000.000110.03194includedK562GPKOW
    SEATXN2ENSG00000204842.10chr12-1119024651119025191118950171118951631119079111119080440.126000.000460.07861includedK562GPKOW
    SENSUN6ENSG00000241058.1chr10-1893249718932569189314041893148418937418189375740.061000.000190.04765includedK562GPKOW
    SEALDOAENSG00000149925.12chr16+3007719630077248300757443007582630078554300786870.074000.000540.08650includedK562GPKOW
    SENBEAL2ENSG00000160796.12chr3+4704855547048645470478084704793947048730470488400.055000.000000.00024includedK562GPKOW
    SEMYSM1ENSG00000162601.5chr1-5915496559155039591547095915478859155897591559210.159000.000040.01410includedK562GPKOW
    SEZNF207ENSG00000010244.12chr17+3069368330693776306923483069250630694790306949620.088000.000630.09400includedK562GPKOW
    SELARP1ENSG00000155506.12chr5+1541733591541734611541731541541732831541736591541738220.060000.000320.06618includedK562GPKOW
    SEPSMD6ENSG00000163636.6chr3-6400841464008477640079936400819964008950640091320.052000.000160.04411includedK562GPKOW
    SETNNT1ENSG00000105048.12chr19-5565780155657834556569115565693355658048556580750.157000.000040.01525includedK562GPKOW
    SESREK1ENSG00000153914.11chr5+6545189265454760654492906544942465455046654551620.144000.000050.01899includedK562GPKOW
    SESREK1ENSG00000153914.11chr5+6546043565460528654596196545975065460610654607250.060000.000690.09918includedK562GPKOW
    SEC6orf48ENSG00000204387.8chr6+3180420031804294318031873180322831805012318052120.328000.000000.00004includedK562GPKOW
    SECOPS3ENSG00000141030.8chr17-1716491317165006171636871716378817165279171654200.073000.000000.00001includedK562GPKOW
    SENDUFV3ENSG00000160194.13chr21+4432329144324386443170364431715744328973443292150.198000.000000.00000includedK562GPKOW
    SETANKENSG00000136560.9chr2+1620336221620337631620177951620179231620361241620362720.134000.000440.07713includedK562GPKOW
    SEFUBP3ENSG00000107164.15chr9+1335065471335066801335060141335061751335069431335070170.058000.000210.05119includedK562GPKOW
    SETOP3BENSG00000100038.15chr22-2233035222330559223300112233017922337126223371840.127000.000260.05854includedK562GPKOW
    SEBAG6ENSG00000204463.8chr6-3160727631607423316068043160700331607975316080830.179000.000000.00076includedK562GPKOW
    SEZFP62ENSG00000196670.9chr5-1802789871802790601802781601802784931802882181802882850.431000.000630.09400includedK562GPKOW
    SEANKHD1ENSG00000131503.16chr5+1399149461399151231399077681399093811399169221399171740.089000.000000.00255includedK562GPKOW
    SENSFL1CENSG00000088833.13chr20-1426639142679414263101426475143313714332750.080000.000360.07083includedK562GPKOW
    SEC14orf159ENSG00000133943.16chr14+9161156491611657915807449158087291623982916240340.184000.000090.03000includedK562GPKOW
    SEPBXIP1ENSG00000163346.12chr1-1549261461549262331549242701549243971549285441549285800.826000.000250.05800includedK562GPKOW
    SEHMGN1ENSG00000205581.6chr21-4071984140719878407177554071788440720217407202650.441000.000000.00072includedK562GPKOW
    SEHNRNPDENSG00000138668.14chr4-8327604783276154832749868327530783276456832765540.104000.000000.00000includedK562GPKOW
    SEDNAJA3ENSG00000103423.9chr16+4504811450492844995544500498450554645067730.144000.000640.09400includedK562GPKOW
    SEPRKAG1ENSG00000181929.7chr12-4939952549399635493992444939932649406844494068930.131000.000170.04504includedK562GPKOW
    SETESENSG00000135269.13chr7+1158745871158746731158505461158507881158890731158893260.113000.000280.06003includedK562GPKOW
    SERCOR1ENSG00000089902.8chr14+1031876561031877141031873431031874211031885231031887530.087000.000600.09240includedK562GPKOW
    SENR2C2ENSG00000177463.11chr3+1504605015046120150453821504549315055095150552960.170000.000610.09267includedK562GPKOW
    SENONOENSG00000147140.11chrX+7050424670504303705034327050357170510478705106410.090000.000110.03297includedK562GPKOW
    SEESYT2ENSG00000117868.11chr7-1585838701585840501585810351585811081585863401585864170.093000.000070.02227includedK562GPKOW
    SESMG5ENSG00000198952.7chr1-1562433541562434391562431511562432411562443871562444770.075000.000010.00490includedK562GPKOW
    SEZSWIM7ENSG00000214941.3chr17-1589011315890206158843531588445815890579158906820.827000.000370.07138includedK562GPKOW
    SECD99L2ENSG00000102181.15chrX-1499967781499968411499844791499845511499997031499997660.101000.000280.06120includedK562GPKOW
    SESLC25A1ENSG00000100075.5chr22-1916545419165554191646321916471719165645191657530.482000.000090.03030includedK562GPKOW
    SEMAPRE3ENSG00000084764.6chr2+2724696327247165272461992724634527248450272486050.059000.000260.05854includedK562GPKOW
    SEHNRNPDLENSG00000152795.13chr4-8334671583346820833457818334603683347189833473320.178000.000000.00000includedK562GPKOW
    SEALG9ENSG00000086848.10chr11-1116758171116760391116570071116572441116803661116804330.117000.000000.00007includedK562GPKOW
    SEZNF766ENSG00000196214.6chr19+5278536352785490527728455277288452786537527866660.367000.000040.01555includedK562GPKOW
    SEDCAKDENSG00000172992.7chr17-4311130243111410431074594310754743111554431117580.337000.000010.00544includedK562GPKOW
    SEBAXENSG00000087088.15chr19+4945894349459090494588044945885649459454494595900.064000.000210.05119includedK562GPKOW
    SELUC7LENSG00000007392.12chr16-2585992586562580762581872706472707460.161000.000520.08406includedK562GPKOW
    SEARPC4-TTLL3ENSG00000250151.5chr3+9870183987025998686809868924987064398710790.152000.000010.00593includedK562GPKOW
    SEMMS22LENSG00000146263.7chr6-9771798297718159977177779771786897720579977207570.473000.000040.01484includedK562GPKOW
    SEMFFENSG00000168958.15chr2+2282119412282121002282050072282050962282203922282204770.189000.000160.04411includedK562GPKOW
    SEMAP3K7ENSG00000135341.13chr6-9126269791262887912617679126189891263176912633050.077000.000080.02618includedK562GPKOW
    SEEXOSC9ENSG00000123737.8chr4+1227372981227373491227350201227352021227375231227376020.190000.000000.00003includedK562GPKOW
    SEIARSENSG00000196305.13chr9-9500292495002973949912829499140895003137950032430.105000.000340.06877includedK562GPKOW
    SENCAPG2ENSG00000146918.15chr7-1584341221584342461584240051584244091584369801584370800.058000.000180.04714includedK562GPKOW
    SEGOLGA4ENSG00000144674.12chr3+3734077837340862373403233734051137343675373438230.077000.000390.07222includedK562GPKOW
    SEPHPT1ENSG00000054148.13chr9+1397449571397450121397444641397445891397452061397454790.124000.000430.07604includedK562GPKOW
    SEGFI1BENSG00000165702.8chr9+1358644471358645851358635831358638551358651281358652940.091000.000020.00912includedK562GPKOW
    SEZCCHC9ENSG00000131732.7chr5+8060055980600960805974308059751780604379806045300.137000.000000.00312includedK562GPKOW
    SEUQCRHENSG00000173660.7chr1+4677556846775716467747724677479946775826467759880.086000.000640.09400includedK562GPKOW
    SEGAS5ENSG00000234741.3chr1-1738346471738346851738343661738344201738358981738359340.058000.000000.00011includedK562GPKOW
    SEREV1ENSG00000135945.5chr2-1000678061000679631000657971000659661000789571000790840.090000.000100.03128includedK562GPKOW
    SERBCK1ENSG00000125826.15chr20+3905243906693887213894233910553914080.121000.000100.03139includedK562GPKOW
    SEMEIOBENSG00000162039.10chr16-1915778191583619119851912117191810719181850.204000.000360.07120includedK562GPKOW
    SENDRG2ENSG00000165795.16chr14-2149218821492298214913992149148021493187214932200.161000.000010.00763includedK562GPKOW
    SESKA2ENSG00000182628.8chr17-5719675657196856571892485718970657208641572087280.126000.000630.09400includedK562GPKOW
    SEPPP2R2AENSG00000221914.4chr8+2619741826197489261964052619650326211983262121490.051000.000170.04518includedK562GPKOW
    SEPPP4R1ENSG00000154845.11chr18-9562919956304495619779562073956337595635480.338000.000010.00436includedK562GPKOW
    SEKLHL5ENSG00000109790.12chr4+3906417839064655390466583904671639077584390777670.208000.000040.01419includedK562GPKOW
    SEHADHBENSG00000138029.9chr2+2648384826483931264772972647734226486247264863470.060000.000150.04299includedK562GPKOW
    SEPOLD4ENSG00000175482.4chr11-6712021167120273671190186711949067120458671205480.530000.000620.09382includedK562GPKOW
    SEPUF60ENSG00000179950.9chr8-1449064821449065661449039871449040831449114491449114690.293000.000420.07556includedK562GPKOW
    SERPL17ENSG00000265681.2chr18-4701810547018203470178864701795447018644470187690.188000.000000.00094includedK562GPKOW
    SENEMFENSG00000165525.13chr14-5026295050263046502625085026266250266192502662420.092000.000000.00003includedK562GPKOW
    SETMEM143ENSG00000161558.6chr19-4886332848863433488485254884861148866547488667880.363000.000610.09279includedK562GPKOW
    SESRRM1ENSG00000133226.12chr1+2497356924973699249731572497328024975349249755200.380000.000000.00000includedK562GPKOW
    SECNOT1ENSG00000125107.12chr16-5865857658658698586331395863341558663631586637290.090000.000250.05725includedK562GPKOW
    SEMIS18BP1ENSG00000129534.9chr14-4570171145701830457003434570050145701935457020230.058000.000680.09856includedK562GPKOW
    SESENP7ENSG00000138468.11chr3-1011177041011178991010908511010909701011777981011778960.387000.000320.06595includedK562GPKOW
    SEFAM192AENSG00000172775.12chr16-5721241357212764572075815720778157219732572199510.175000.000010.00544includedK562GPKOW
    SEPTPN12ENSG00000127947.11chr7+7721074377210820772003947720050377214859772148980.098000.000620.09396includedK562GPKOW
    SEPPFIA1ENSG00000131626.11chr11+7019602870196145701942947019452670200406702005580.167000.000000.00114includedK562GPKOW
    SEZNF468ENSG00000204604.5chr19-5335712453357360533523395335246653357510533575980.251000.000220.05237includedK562GPKOW
    SEFAM160B2ENSG00000158863.17chr8+2195948621959573219592182195936221959685219598260.116000.000000.00023includedK562GPKOW
    SEZNF512ENSG00000243943.5chr2+2783968527839812278391282783919127840339278404380.086000.000490.08130includedK562GPKOW
    SEITPR3ENSG00000096433.6chr6+3366081033660895336605203366067033661321336614820.063000.000550.08758includedK562GPKOW
    SESRSF3ENSG00000112081.12chr6+3656759736568053365665413656676036568928365689670.098000.000020.00849includedK562GPKOW
    SEPARLENSG00000175193.8chr3-1835515111835516131835512791835513771835583571835584280.238000.000000.00255includedK562GPKOW
    SEOR2W3ENSG00000238243.2chr1+2480392012480393392480312762480313652480588582480604490.282000.000320.06618includedK562GPKOW
    SEUCHL5ENSG00000116750.9chr1-1929970041929970851929929731929930761929972141929972780.114000.000000.00001includedK562GPKOW
    SECOA4ENSG00000181924.6chr11-7358752373587620735840417358443973587801735878880.126000.000040.01472includedK562GPKOW
    SEMAXENSG00000125952.14chr14-6554406165544146655431796554338165544630655447540.124000.000000.00000includedK562GPKOW
    SETIAL1ENSG00000151923.13chr10-1213363581213364171213361221213362621213365911213367260.083000.000020.00850includedK562GPKOW
    SETIAL1ENSG00000151923.13chr10-1213399821213403581213394461213395221213414331213415210.447000.000000.00017includedK562GPKOW
    SESS18ENSG00000141380.9chr18-2361579423615887236149682361509123618518236186230.143000.000030.01098includedK562GPKOW
    SESTRBPENSG00000165209.14chr9-1259018071259019661258986591258987941259091331259093330.058000.000350.07057includedK562GPKOW
    SERPS24ENSG00000138326.14chr10+7979996179799983797969517979706279800372798004550.097000.000000.00004includedK562GPKOW
    SEUBE4AENSG00000110344.5chr11+1182527291182529131182521051182522381182533031182534910.061000.000020.00850includedK562GPKOW
    SEBRPF1ENSG00000156983.11chr3+9784035978422597837089783855978462797849370.286000.000600.09264includedK562GPKOW





    2 RBPs can affect the splicing of GPKOW :

    Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
    A3SSGPKOWENSG00000068394.9chrX-4897252848972705489725284897267748973383489735160.063000.000020.00370longerK562AKAP8L
    A3SSGPKOWENSG00000068394.9chrX-4897224448972442489722444897236848972574489726770.085000.000000.00000longerK562AQR

    *: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
    **: "-log(0)" was displayed as "99999.99999".





    No autoregularoty alternative splicing events between protein GPKOW and its RNA.