HMGCR

General Information

Gene Name       : HMGCR
Gene ID             : ENSG00000113161.15
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: HMGCR)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878HMGCRENSG00000113161.1575.7760.7168.24ENCSR000AEF
HepG2HMGCRENSG00000113161.1564.2595.0079.62ENCSR985KAT
K562HMGCRENSG00000113161.1545.1945.0145.10ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for HMGCR is not avaliable on ENCORE database.



Proteins bound to RNA
  • HMGCR RNA is bound by 47 proteins.  







eCLIP assay for HMGCR is not avaliable on ENCORE database.





47 proteins are bound to HMGCR RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr57465714374657193+3'-UTR3.582244.96262HepG2TIAL1
chr57465612474656169+3'-UTR,CDS4.834954.35919HepG2SND1
chr57465727874657326+3'-UTR4.759846.75461HepG2AKAP1
chr57465722274657288+3'-UTR3.6812725.20390HepG2DDX55
chr57465751774657590+3'-UTR3.534134.96262HepG2TIAL1
chr57465714574657242+3'-UTR4.9877845.92387K562PUM2
chr57465722674657264+3'-UTR4.9972425.15993HepG2FUBP3
chr57463837674638436+3'-UTR,5'-UTR,CDS,intron-Proximal3.4829710.18067K562GPKOW
chr57465719674657226+3'-UTR5.1763333.59370HepG2FUBP3
chr57465728374657319+3'-UTR4.636248.86033HepG2FUBP3
chr57465646574656535+3'-UTR4.822497.39978HepG2UPF1
chr57465714874657268+3'-UTR3.4642113.83806K562DDX6
chr57465717774657327+3'-UTR4.8892517.31440HepG2DDX6
chr57465661474656742+3'-UTR4.1805917.21100HepG2UPF1
chr57465772274657812+3'-UTR4.0369711.01033HepG2DDX55
chr57465724974657382+3'-UTR4.3810115.14578HepG2UPF1
chr57465623474656284+3'-UTR3.120226.70604HepG2BCLAF1
chr57465752974657581+3'-UTR4.7831816.17684K562PUM2
chr57465769274657722+3'-UTR4.5848418.52815HepG2FUBP3
chr57463835474638442+3'-UTR,5'-UTR,CDS,intron-Proximal3.4234520.60138HepG2BUD13
chr57465713774657211+3'-UTR3.314544.74971K562CPEB4
chr57465769574657728+3'-UTR3.921943.49438K562DDX6
chr57465781574657842+3'-UTR4.413366.12308K562PUM2
chr57465714874657215+3'-UTR3.474697.31176K562UPF1
chr57463835674638444+3'-UTR,5'-UTR,CDS,intron-Proximal5.5386622.23964HepG2AQR
chr57465767574657722+3'-UTR4.4745110.26584HepG2DDX55
chr57465778874657859+3'-UTR4.2849714.36777HepG2FUBP3
chr57465762274657692+3'-UTR4.7046913.96801HepG2FUBP3
chr57463835274638436+3'-UTR,5'-UTR,CDS,intron-Proximal3.226956.94390K562SF3B4
chr57465773474657780+3'-UTR3.8298512.15945HepG2FUBP3
chr57465751874657592+3'-UTR4.5085325.51939HepG2FUBP3
chr57463836674638437+3'-UTR,5'-UTR,CDS,intron-Proximal3.281627.34413K562BUD13
chr57465612074656195+3'-UTR,CDS3.0882613.75898HepG2GRWD1
chr57465682574656869+3'-UTR3.451164.37320K562PUM2
chr57463840674638442+3'-UTR,5'-UTR,CDS,intron-Proximal3.656814.46344HepG2DDX3X
chr57465659374656651+3'-UTR3.098874.63794HepG2AKAP1
chr57465610974656170+3'-UTR,CDS,intron-Proximal3.046765.56943HepG2ZNF800
chr57465770874657791+3'-UTR4.093784.24308HepG2TIAL1
chr57465714674657196+3'-UTR5.3466241.85755HepG2FUBP3
chr57465733674657377+3'-UTR3.180534.11795K562YBX3
chr57465662574656675+3'-UTR3.957905.19413HepG2LIN28B
chr57463305974633116+5'-UTR,intron-Distal3.9080114.03068HepG2DDX3X
chr57463311674633126+5'-UTR,intron-Distal,intron-Proximal3.682466.07214HepG2DDX3X
chr57463306074633126+5'-UTR,intron-Distal,intron-Proximal3.6483610.54772K562DDX3X
chr57463312474633140+5'-UTR,intron-Distal,intron-Proximal3.867475.30069HepG2AQR
chr57465087974650914+CDS,intron-Distal,intron-Proximal4.8158510.03221HepG2LIN28B
chr57464613174646195+CDS3.669357.86922HepG2RPS3
chr57464731674647410+CDS3.778527.15650K562SND1
chr57463978774639848+CDS,intron-Proximal3.724449.30654K562AQR
chr57465226574652312+CDS,intron-Proximal3.285896.92749HepG2PRPF8
chr57465609374656164+CDS,intron-Proximal3.294578.96851HepG2AQR
chr57465512174655134+CDS,intron-Distal4.113153.77218HepG2SND1
chr57463848374638518+CDS4.413878.77766HepG2RPS3
chr57465577574655830+CDS,intron-Proximal3.413158.51251HepG2PRPF8
chr57465091174650950+CDS,intron-Distal3.782654.99078K562SND1
chr57465123674651322+CDS4.4370014.34717HepG2SND1
chr57464008674640152+CDS3.806378.01224K562SND1
chr57465499574655080+CDS,intron-Distal3.458704.96321K562LIN28B
chr57464608374646153+CDS3.867227.21038HepG2SND1
chr57465499474655035+CDS,intron-Distal,intron-Proximal4.139186.31664HepG2LIN28B
chr57465503974655092+CDS,intron-Distal3.276764.80460HepG2AQR
chr57464661274646678+CDS,intron-Proximal4.2634210.36200HepG2SND1
chr57464670874646774+CDS4.9214410.23121K562XRCC6
chr57465512174655166+CDS,intron-Distal,intron-Proximal4.360308.11807HepG2PRPF8
chr57465222474652267+CDS3.721133.98500HepG2SND1
chr57465216774652182+CDS,intron-Proximal4.422835.27247HepG2RPS3
chr57465460574654651+CDS3.033379.54333HepG2RPS3
chr57464307174643135+CDS,intron-Proximal4.6714513.45818K562SND1
chr57465583474655948+CDS3.5859122.71512HepG2RPS3
chr57463967974639712+CDS3.251213.27746HepG2LIN28B
chr57465045474650513+CDS4.375505.57500K562SND1
chr57464014774640187+CDS,intron-Proximal4.580483.86479HepG2PRPF8
chr57465530974655371+CDS,intron-Distal3.753516.64821HepG2SND1
chr57464720074647266+CDS,intron-Proximal3.088783.61318K562KHSRP
chr57465594174655965+CDS,intron-Proximal3.591524.50825K562DDX24
chr57465577874655845+CDS,intron-Proximal5.4343139.98468K562AQR
chr57465575474655822+CDS,intron-Proximal3.629365.60187K562GPKOW
chr57464595974645973+CDS3.990179.41070K562SND1
chr57464613774646200+CDS,intron-Proximal3.012946.23258K562SND1
chr57465577374655839+CDS,intron-Proximal4.2201311.40067HepG2AQR
chr57465531274655367+CDS,intron-Distal3.789763.89440HepG2ZNF800
chr57464003674640098+CDS,intron-Proximal3.391507.07421HepG2BUD13
chr57464311774643135+CDS,intron-Proximal5.037147.33420HepG2SND1
chr57463963474639694+CDS,intron-Proximal4.900688.05832K562SF3B4
chr57464742674647465+CDS,intron-Proximal4.138505.97994K562AQR
chr57464734274647423+CDS3.490125.52428HepG2UCHL5
chr57465494074655039+CDS,intron-Distal,intron-Proximal4.8500912.85265HepG2AQR
chr57464676774646774+CDS3.460647.42278HepG2BCLAF1
chr57465574974655821+CDS,intron-Proximal4.291598.28159K562SF3B4
chr57464616374646200+CDS,intron-Proximal4.598575.54337HepG2SND1
chr57465531074655370+CDS,intron-Distal3.209725.82908HepG2AQR
chr57463966174639712+CDS,intron-Proximal3.366995.36452K562U2AF2
chr57464586574645887+CDS,intron-Proximal4.132398.25779K562SND1
chr57465045774650516+CDS3.035695.04837HepG2ZNF800
chr57465115374651229+CDS,intron-Proximal5.295277.23427HepG2AQR
chr57465504674655095+CDS,intron-Distal3.729066.36878HepG2SND1
chr57463976674639837+CDS,intron-Proximal4.607707.46483HepG2PRPF8
chr57465099074651040+CDS,intron-Distal,intron-Proximal3.2562410.59174HepG2RPS3
chr57465510874655139+CDS,intron-Distal,intron-Proximal4.730907.71151HepG2GRWD1
chr57464608274646137+CDS,intron-Proximal4.6278616.20884K562SND1
chr57465537674655421+CDS,intron-Distal,intron-Proximal4.4082713.85806HepG2AQR
chr57463844674638490+CDS4.352228.37444K562RBM15
chr57465046674650502+CDS3.821645.80295HepG2PPIG
chr57463978074639852+CDS,intron-Proximal3.834664.48980K562PRPF8
chr57464140274641475+CDS4.1029511.26486K562SND1
chr57465092274650957+CDS,intron-Distal3.559944.12428HepG2SND1
chr57465051174650522+CDS3.806705.75355HepG2LIN28B
chr57464609974646198+CDS3.444519.29110K562DDX24
chr57465096774651035+CDS,intron-Distal3.507606.28780K562DDX24
chr57464661274646707+CDS,intron-Proximal3.9402714.31317K562SND1
chr57465115574651218+CDS,intron-Proximal4.6236311.83800K562AQR
chr57465125674651279+CDS3.167934.69671HepG2PPIG
chr57465091174650965+CDS,intron-Distal3.528515.77413K562DDX24
chr57464736074647421+CDS3.561455.70746HepG2SND1
chr57465525474655270+CDS,intron-Distal3.410254.25142K562BUD13
chr57464304274643071+CDS4.780004.42935K562SND1
chr57465510174655136+CDS,intron-Distal,intron-Proximal3.050544.67452HepG2G3BP1
chr57465033874650414+CDS4.575136.46034K562SND1
chr57465118774651281+CDS,intron-Proximal3.5685014.97650HepG2RPS3
chr57463849074638509+CDS4.908276.54449K562RBM15
chr57464619074646199+CDS3.207233.50639HepG2PPIG
chr57465118774651236+CDS,intron-Proximal4.2243414.73337HepG2SND1
chr57465585774655944+CDS3.317504.30200K562LIN28B
chr57465128174651348+CDS,intron-Proximal3.5172510.63502HepG2RPS3
chr57465529474655364+CDS,intron-Distal3.1313317.95683HepG2BCLAF1
chr57465026474650330+CDS,intron-Proximal5.9210324.87313K562SF3B4
chr57464585374645914+CDS,intron-Proximal3.062034.47008K562U2AF2
chr57464613674646185+CDS3.0304810.78867HepG2BCLAF1
chr57465132774651346+CDS3.496786.60490HepG2BCLAF1
chr57464586674645894+CDS,intron-Proximal4.083706.35450HepG2SND1
chr57464594974646007+CDS,intron-Proximal4.420265.64484HepG2PRPF8
chr57464075074640771+intron-Distal3.855325.78064K562KHSRP
chr57464576474645794+intron-Distal,intron-Proximal4.900487.22462K562U2AF1
chr57464326774643315+intron-Distal3.774484.94908K562TIA1
chr57463317574633249+intron-Distal,intron-Proximal3.6779910.23609HepG2BUD13
chr57463326474633327+intron-Distal5.019417.66618HepG2PRPF4
chr57465478174654820+intron-Distal4.580594.21433K562PRPF8
chr57463332274633379+intron-Distal4.1022410.32060HepG2XPO5
chr57463314074633167+intron-Distal,intron-Proximal3.229055.54603HepG2AQR
chr57463327574633326+intron-Distal4.589613.31153K562GTF2F1
chr57464077174640806+intron-Distal4.977969.41035K562KHSRP
chr57463316374633215+intron-Distal,intron-Proximal5.0787237.29653HepG2EFTUD2
chr57464576574645797+intron-Distal,intron-Proximal5.317009.30608K562U2AF2
chr57463338974633571+intron-Distal3.032795.78662HepG2GTF2F1
chr57463327474633328+intron-Distal5.275824.83371K562EFTUD2
chr57464760674647692+intron-Distal3.031364.31458HepG2TIAL1
chr57463358274633631+intron-Distal3.860677.19609HepG2EFTUD2
chr57463328174633327+intron-Distal3.492374.20880HepG2GTF2F1
chr57464576574645812+intron-Distal,intron-Proximal4.384409.48825HepG2U2AF2
chr57463357074633628+intron-Distal3.065355.39895K562DROSHA
chr57463321574633270+intron-Distal,intron-Proximal5.4626932.63304HepG2EFTUD2
chr57463981174639930+intron-Distal,intron-Proximal3.6772310.26213HepG2KHSRP
chr57463319474633277+intron-Distal,intron-Proximal3.8133912.71022K562DROSHA
chr57463327074633327+intron-Distal4.7494710.83708HepG2EFTUD2
chr57463327274633339+intron-Distal4.3420710.30731K562CSTF2T
chr57464074974640799+intron-Distal3.870743.22073HepG2KHSRP
chr57463317374633275+intron-Distal,intron-Proximal5.2719011.38030K562GTF2F1
chr57463317174633259+intron-Distal,intron-Proximal5.6134522.16105HepG2GTF2F1
chr57463319074633265+intron-Distal,intron-Proximal3.372594.17268HepG2CDC40
chr57463318474633274+intron-Distal,intron-Proximal3.9481516.55771K562EFTUD2
chr57463344774633485+intron-Distal3.618385.15405HepG2PRPF4
chr57463652974636674+intron-Distal3.526134.64200K562KHDRBS1
chr57465486174654904+intron-Distal,intron-Proximal3.334663.76553K562PRPF8
chr57463317274633272+intron-Distal,intron-Proximal3.9985413.06032K562CSTF2T
chr57465538174655417+intron-Distal,intron-Proximal5.9555645.82689K562AQR
chr57463315474633257+intron-Distal,intron-Proximal3.8219413.80214HepG2FAM120A
chr57464890974648989+intron-Distal5.5505711.85065K562TARDBP
chr57463329174633376+intron-Distal5.9237313.96605HepG2HNRNPM
chr57463313774633264+intron-Distal,intron-Proximal5.0945226.72882HepG2PRPF4
chr57463316774633207+intron-Distal,intron-Proximal3.247314.23709HepG2AQR
chr57463317474633255+intron-Distal,intron-Proximal3.319788.12187K562GEMIN5
chr57463338974633447+intron-Distal5.7766915.54949HepG2PRPF4
chr57463995174640037+intron-Distal,intron-Proximal3.391075.23331K562KHSRP
chr57464080674640885+intron-Distal3.834716.82127K562KHSRP
chr57463328774633338+intron-Distal3.399273.59190K562TIA1
chr57463316174633340+intron-Distal,intron-Proximal4.679953.30336K562EWSR1
chr57465541874655448+intron-Distal,intron-Proximal6.4603653.05825K562AQR
chr57463315474633232+intron-Distal,intron-Proximal4.008514.60998HepG2PCBP2
chr57465539174655447+intron-Distal,intron-Proximal4.066478.16617HepG2PRPF8
chr57463986174639951+intron-Distal,intron-Proximal4.051786.59733K562KHSRP
chr57463345374633498+intron-Distal4.512825.40707K562CSTF2T
chr57464716374647218+intron-Proximal3.880513.10582HepG2TIAL1
chr57464294274643015+intron-Proximal5.138875.97591K562QKI
chr57465227374652314+intron-Proximal5.430987.63570K562AQR
chr57464579774645812+intron-Proximal4.871946.58556K562U2AF2
chr57464715874647219+intron-Proximal4.954787.86563K562TIA1
chr57463980674639860+intron-Proximal4.143553.31824HepG2TIAL1
chr57463838174638394+intron-Proximal3.234825.46476K562AQR
chr57463981174639853+intron-Proximal5.252596.16999K562TIA1
chr57465577474655778+intron-Proximal6.7570221.90147K562AQR
chr57464716774647208+intron-Proximal5.025556.55845K562RBM22
chr57464297374643022+intron-Proximal4.5952510.58655HepG2QKI
chr57465606574656107+intron-Proximal4.749154.90235K562SF3B4
chr57463982774639861+intron-Proximal3.105963.13086K562KHSRP
chr57464298574643028+intron-Proximal4.311916.59856K562SF3B4
chr57464579474645811+intron-Proximal4.354524.61740K562U2AF1
chr57464297174642998+intron-Proximal3.961023.73609HepG2KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for HMGCR is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for HMGCR is not available on ENCORE database.

  • 180 RBPs can affect the levels of HMGCR.  








The Knockdown/knockout RNA-Seq assay for HMGCR is not available on ENCORE database.





180 RBPs can affect the gene expression of HMGCR :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
HMGCRENSG00000113161.113652.629205725.38470-0.648408.636407.10790HepG2ABCF1
HMGCRENSG00000113161.113969.538206004.21610-0.5970022.0309020.68530HepG2ACO1
HMGCRENSG00000113161.115286.483103495.340700.596807.184505.67250HepG2ADAR
HMGCRENSG00000113161.112225.0410015950.47940-2.8417050.7720048.93440HepG2AKAP1
HMGCRENSG00000113161.114188.963405352.08330-0.353502.678101.65620HepG2AKAP8
HMGCRENSG00000113161.119669.253007188.336000.427604.851003.98300HepG2AUH
HMGCRENSG00000113161.116222.222204524.701600.459504.789103.63530HepG2BCLAF1
HMGCRENSG00000113161.119366.332704236.868001.1444014.4059012.88430HepG2CALR
HMGCRENSG00000113161.113029.467404017.68910-0.407304.868402.07740HepG2CEBPZ
HMGCRENSG00000113161.113765.085406002.37050-0.6728033.4586031.73100HepG2CKAP4
HMGCRENSG00000113161.116516.788103442.637600.9205019.2452017.62930HepG2CPSF6
HMGCRENSG00000113161.113943.494404714.77120-0.257702.413701.38370HepG2CPSF7
HMGCRENSG00000113161.112438.880903216.67610-0.399403.732102.50070HepG2CSTF2
HMGCRENSG00000113161.112440.039503430.88720-0.491703.576001.95100HepG2CSTF2T
HMGCRENSG00000113161.114080.960305909.78570-0.5342014.1390012.90570HepG2CELF1
HMGCRENSG00000113161.1110687.431806354.595300.7499021.2238019.52580HepG2DAZAP1
HMGCRENSG00000113161.113511.445005552.79110-0.6611028.4183026.45860HepG2DDX19B
HMGCRENSG00000113161.112235.913703589.45970-0.6829011.412609.32660HepG2DDX1
HMGCRENSG00000113161.115575.468303697.619700.592409.557008.37710HepG2DDX21
HMGCRENSG00000113161.116691.446903618.059400.8870024.7813022.37040HepG2DDX24
HMGCRENSG00000113161.1110415.4905015280.32370-0.552905.067004.24240HepG2DDX3X
HMGCRENSG00000113161.115413.168603359.584900.688105.726103.91080HepG2DDX47
HMGCRENSG00000113161.112981.637705119.38650-0.779909.674908.33100HepG2DDX55
HMGCRENSG00000113161.116564.426103909.394100.747605.024603.72110HepG2DDX59
HMGCRENSG00000113161.117936.606304950.803800.6808010.963909.10920HepG2DDX5
HMGCRENSG00000113161.115351.7911013123.82740-1.2941018.3539016.95320HepG2DDX6
HMGCRENSG00000113161.115752.690003394.714600.7608015.2255013.21770HepG2DHX30
HMGCRENSG00000113161.1111423.955305744.267900.9918059.0732057.02440HepG2DKC1
HMGCRENSG00000113161.112035.665603488.48200-0.7771035.7656033.66790HepG2DNAJC2
HMGCRENSG00000113161.111812.031102944.50050-0.700409.798207.74200HepG2EFTUD2
HMGCRENSG00000113161.115320.884403404.674100.644005.250603.72710HepG2AGO1
HMGCRENSG00000113161.116812.3983012618.52330-0.889308.906607.88060HepG2EIF2S1
HMGCRENSG00000113161.112621.412604343.03440-0.7284016.0011013.54560HepG2EIF2S2
HMGCRENSG00000113161.111612.631702867.21180-0.8302011.430309.73270HepG2EIF3D
HMGCRENSG00000113161.114252.651103491.574000.284403.001501.88120HepG2EIF3G
HMGCRENSG00000113161.1111139.655606005.407100.8913019.0680017.08210HepG2EIF4G2
HMGCRENSG00000113161.117056.838404959.497100.508706.857505.23490HepG2ESF1
HMGCRENSG00000113161.115087.009408252.47720-0.698006.706805.83800HepG2ETF1
HMGCRENSG00000113161.112121.252902562.46530-0.272602.638501.49930HepG2FAM120A
HMGCRENSG00000113161.116994.587203219.453501.119306.860803.96500HepG2FASTKD1
HMGCRENSG00000113161.112444.686705781.21900-1.2417024.3659022.50270HepG2FIP1L1
HMGCRENSG00000113161.115526.842603448.703300.680302.507301.54250HepG2FTO
HMGCRENSG00000113161.114567.378507296.88440-0.675907.032105.81610HepG2FUBP3
HMGCRENSG00000113161.113211.551904221.23000-0.394402.333801.30440HepG2FUS
HMGCRENSG00000113161.119169.1885014067.65740-0.617505.656904.68980HepG2FXR1
HMGCRENSG00000113161.116316.949703902.280800.694809.003507.89220HepG2GPKOW
HMGCRENSG00000113161.112764.365903977.15920-0.524803.379401.63270HepG2GTF2F1
HMGCRENSG00000113161.113616.657605731.97960-0.6644023.6605021.27920HepG2HDGF
HMGCRENSG00000113161.112102.688203119.43010-0.569003.408001.87870HepG2HNRNPA0
HMGCRENSG00000113161.115046.919803553.416600.506107.266006.29280HepG2HNRNPA1
HMGCRENSG00000113161.114311.077705839.99490-0.4379010.849709.22700HepG2HNRNPA2B1
HMGCRENSG00000113161.112218.070803045.99340-0.457603.286301.75890HepG2HNRNPAB
HMGCRENSG00000113161.115653.190103952.473700.516206.762305.71580HepG2HNRNPC
HMGCRENSG00000113161.113719.420902690.378000.4672010.456609.17930HepG2HNRNPF
HMGCRENSG00000113161.115672.4642013211.80980-1.2198020.2704018.53890HepG2HNRNPK
HMGCRENSG00000113161.111709.052405788.58780-1.76000195.26230191.71710HepG2HNRNPL
HMGCRENSG00000113161.1113481.773203724.038101.8560070.8310068.37640HepG2HNRNPLL
HMGCRENSG00000113161.112711.989903926.34570-0.5338015.0563013.73230HepG2HNRNPU
HMGCRENSG00000113161.118326.265405826.702300.514902.762301.53690HepG2HSPD1
HMGCRENSG00000113161.114434.695602649.243100.7432016.9835015.36660HepG2IGF2BP1
HMGCRENSG00000113161.1120724.1361013267.249600.643309.475908.31020HepG2IGF2BP2
HMGCRENSG00000113161.116563.5798012448.23750-0.923404.995003.68960HepG2IGF2BP3
HMGCRENSG00000113161.112558.739704010.63990-0.6484029.5218027.45850HepG2ILF2
HMGCRENSG00000113161.116675.268303594.754500.892804.857203.08700HepG2ILF3
HMGCRENSG00000113161.114665.766503514.903100.408502.903301.67680HepG2KHDRBS1
HMGCRENSG00000113161.119581.6104013343.42350-0.477803.502302.35780HepG2KHSRP
HMGCRENSG00000113161.112144.459304051.58970-0.917906.776505.04070HepG2LARP7
HMGCRENSG00000113161.118807.5930014151.85650-0.684207.593106.58760HepG2MATR3
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HMGCRENSG00000113161.115933.128903798.509500.643304.902103.58840HepG2MTPAP
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HMGCRENSG00000113161.113988.236906301.19690-0.6599013.2647011.64880HepG2NOL12
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HMGCRENSG00000113161.117158.193703370.482501.086504.969403.75170HepG2PABPC1
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HMGCRENSG00000113161.117043.513403386.010901.0566057.5700055.06000HepG2PRPF4
HMGCRENSG00000113161.115751.682004201.123200.453102.667301.46760HepG2PRPF6
HMGCRENSG00000113161.118301.5562013202.67050-0.6694020.3617019.13970HepG2PTBP1
HMGCRENSG00000113161.1111465.413206015.009100.9305025.3803023.81760HepG2PUF60
HMGCRENSG00000113161.113933.110206385.15690-0.6991039.4889037.78370HepG2PUM1
HMGCRENSG00000113161.118054.189806380.518300.336004.794603.92330HepG2PUM2
HMGCRENSG00000113161.1111988.217306115.604400.9710053.4595051.46540HepG2PUS1
HMGCRENSG00000113161.1117076.2932014299.758200.255903.396702.71380HepG2QKI
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HMGCRENSG00000113161.113920.210806897.68860-0.815207.186406.44300HepG2RBM22
HMGCRENSG00000113161.1116833.1714012977.594500.375201.868001.30510HepG2RBM25
HMGCRENSG00000113161.118013.172803561.599601.169707.956505.44200HepG2RBM47
HMGCRENSG00000113161.115677.8892014693.67110-1.3718059.9111058.17260HepG2NELFE
HMGCRENSG00000113161.115962.5559013684.49290-1.1985058.3951056.36220HepG2RECQL
HMGCRENSG00000113161.113487.864002898.364400.267002.037401.44030HepG2RPLP0
HMGCRENSG00000113161.119060.682703787.755501.2582016.7853014.70470HepG2RPS10
HMGCRENSG00000113161.112187.152702789.88010-0.351103.765403.05850HepG2RPS19
HMGCRENSG00000113161.115493.901203703.954600.568704.676103.63850HepG2RPS3A
HMGCRENSG00000113161.113124.447604599.20620-0.557803.059601.92820HepG2RPS5
HMGCRENSG00000113161.112132.937703907.37700-0.8734012.0906010.63350HepG2RRP9
HMGCRENSG00000113161.112357.622103496.61110-0.5686018.5046017.05310HepG2SAFB2
HMGCRENSG00000113161.115952.723703487.873900.771109.006106.76150HepG2SART3
HMGCRENSG00000113161.117573.9034013746.47510-0.8600036.2436034.55240HepG2SF3B4
HMGCRENSG00000113161.118718.457105767.372100.5961029.8549028.03450HepG2SLBP
HMGCRENSG00000113161.111968.075503929.97710-0.9977012.2537010.16930HepG2SMNDC1
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HMGCRENSG00000113161.116312.350804876.204700.372303.365701.57390HepG2SRP68
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HMGCRENSG00000113161.118913.618205938.896300.5857021.0572019.54830HepG2SRSF5
HMGCRENSG00000113161.113236.893602643.246300.292204.318703.47920HepG2SRSF7
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HMGCRENSG00000113161.1111172.511905096.485801.1323024.0285022.39190HepG2SUPV3L1
HMGCRENSG00000113161.1110628.1621012895.66490-0.279004.715704.01500HepG2TAF15
HMGCRENSG00000113161.115246.115703630.360000.531007.198806.10540HepG2TARDBP
HMGCRENSG00000113161.119335.394005703.093300.710903.601702.39010HepG2TBRG4
HMGCRENSG00000113161.119022.4470011850.30980-0.393305.390504.23630HepG2TIA1
HMGCRENSG00000113161.115763.980503815.348200.5952010.821709.94530HepG2TIAL1
HMGCRENSG00000113161.114599.737603849.272400.256904.257803.58750HepG2TRIM56
HMGCRENSG00000113161.111676.819802278.37060-0.442303.130101.46950HepG2TROVE2
HMGCRENSG00000113161.113899.030904945.34320-0.343003.140302.47360HepG2U2AF1
HMGCRENSG00000113161.114757.935506219.97200-0.386603.431902.49800HepG2UBE2L3
HMGCRENSG00000113161.111441.419803010.79820-1.0627019.5499017.57760HepG2UCHL5
HMGCRENSG00000113161.1110136.851808213.284900.303507.243206.20240HepG2UPF1
HMGCRENSG00000113161.114366.485903317.730400.396202.410901.39770HepG2XPO5
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HMGCRENSG00000113161.115252.761403341.362900.6525017.3711015.94050HepG2ZC3H8
HMGCRENSG00000113161.116038.834303852.496900.648405.857503.88700HepG2ZRANB2
HMGCRENSG00000113161.113221.574105309.11090-0.720703.584102.17170K562ABCF1
HMGCRENSG00000113161.111496.837202521.20710-0.752203.410901.50070K562ADAR
HMGCRENSG00000113161.115258.843204180.456300.331002.095401.58920K562AGGF1
HMGCRENSG00000113161.114704.234006059.07130-0.365106.404804.06370K562AKAP1
HMGCRENSG00000113161.119443.055004350.095101.1181029.9787027.40280K562AKAP8L
HMGCRENSG00000113161.115810.816809779.33290-0.751005.745103.85420K562APOBEC3C
HMGCRENSG00000113161.116482.321109868.84560-0.606404.000403.32000K562AQR
HMGCRENSG00000113161.118047.866904564.563100.8180013.1824011.02320K562ATP5C1
HMGCRENSG00000113161.113683.802204759.64650-0.369705.048703.73610K562BCLAF1
HMGCRENSG00000113161.111326.404103329.60080-1.327806.182804.86800K562BOP1
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HMGCRENSG00000113161.116695.817308391.58970-0.325703.255301.85050K562CIRBP
HMGCRENSG00000113161.113528.999507429.63520-1.0740010.827708.72520K562CNOT7
HMGCRENSG00000113161.111996.324903540.63350-0.826702.962502.15110K562CPSF6
HMGCRENSG00000113161.112781.855803610.90040-0.376306.204504.53600K562CSTF2
HMGCRENSG00000113161.1110172.0054013632.31880-0.422402.313001.42140K562CELF1
HMGCRENSG00000113161.111663.816202600.95070-0.644504.167501.87720K562DDX1
HMGCRENSG00000113161.112231.331307498.57050-1.7487016.8693015.38110K562DDX47
HMGCRENSG00000113161.114469.450506224.98060-0.478008.486305.90830K562DDX6
HMGCRENSG00000113161.111363.712902763.42810-1.018907.501705.17090K562DHX30
HMGCRENSG00000113161.117926.577704680.130900.760009.396007.57710K562DKC1
HMGCRENSG00000113161.111551.489902654.72370-0.774907.739505.58430K562DNAJC21
HMGCRENSG00000113161.111681.561902814.04380-0.742804.836302.47840K562DNAJC2
HMGCRENSG00000113161.112029.510404166.05280-1.0375014.1682011.56390K562EEF2
HMGCRENSG00000113161.113025.099304025.54920-0.412203.591402.54180K562EFTUD2
HMGCRENSG00000113161.114528.531106744.43570-0.5747011.363608.88070K562EIF2S1
HMGCRENSG00000113161.112239.097804578.87540-1.032108.968607.78690K562EIF2S2
HMGCRENSG00000113161.11575.464902511.13340-2.1255029.1745026.41420K562EIF3A
HMGCRENSG00000113161.112205.072604310.69050-0.9671014.0529011.56110K562EIF3D
HMGCRENSG00000113161.112348.974504736.76820-1.0119013.9754012.13920K562EIF3G
HMGCRENSG00000113161.113212.742106414.67570-0.9976012.9177011.09050K562EIF4A3
HMGCRENSG00000113161.114455.388105776.93350-0.374805.644703.90560K562EIF4B
HMGCRENSG00000113161.111239.274802695.48370-1.121003.630601.34630K562EIF4G1
HMGCRENSG00000113161.114675.5315011083.59990-1.2452016.7803014.58750K562EIF4G2
HMGCRENSG00000113161.112619.758504059.37450-0.631803.023601.32140K562ESF1
HMGCRENSG00000113161.112587.715703214.33860-0.312802.663501.42240K562EXOSC5
HMGCRENSG00000113161.112680.232403504.51810-0.386903.260302.01960K562FKBP4
HMGCRENSG00000113161.111820.211703601.90560-0.984704.276303.21340K562FMR1
HMGCRENSG00000113161.111442.997403052.67730-1.081004.308503.14440K562FTO
HMGCRENSG00000113161.112987.812604035.82610-0.433803.940402.20140K562GEMIN5
HMGCRENSG00000113161.111740.309503380.68350-0.958004.156303.18700K562GPKOW
HMGCRENSG00000113161.113582.998206100.85370-0.767803.622302.76150K562GRSF1
HMGCRENSG00000113161.114205.850705800.81340-0.463907.236205.56760K562HNRNPA1
HMGCRENSG00000113161.114390.714206952.19870-0.663005.130402.98830K562HNRNPAB
HMGCRENSG00000113161.111282.131704037.02260-1.6547066.9201064.14580K562HNRNPC
HMGCRENSG00000113161.112974.983103604.96640-0.277102.581901.48450K562HNRNPF
HMGCRENSG00000113161.114999.918307820.44090-0.645309.298206.98640K562HNRNPK
HMGCRENSG00000113161.112571.505806777.38600-1.3981012.090209.73410K562HNRNPL
HMGCRENSG00000113161.113589.578106423.67870-0.8396028.4817025.90640K562HNRNPU
HMGCRENSG00000113161.112510.478005174.65180-1.043506.644005.42280K562HSPD1
HMGCRENSG00000113161.115995.056007962.76830-0.409504.933803.25290K562IGF2BP3
HMGCRENSG00000113161.111823.682802578.97040-0.499904.314902.44020K562ILF3
HMGCRENSG00000113161.118202.306104616.044600.829306.415505.03890K562KIF1C
HMGCRENSG00000113161.111399.786902886.02690-1.043904.626303.38070K562KRR1
HMGCRENSG00000113161.115153.432308228.65640-0.6751013.7223011.72740K562MAGOH
HMGCRENSG00000113161.116450.420408212.24580-0.348404.376503.19210K562MATR3
HMGCRENSG00000113161.1110089.057605171.204800.9641018.6037016.00040K562MBNL1
HMGCRENSG00000113161.111477.336203299.81890-1.159405.178303.95770K562METAP2
HMGCRENSG00000113161.117381.6188011813.33150-0.678407.516805.70770K562MSI2
HMGCRENSG00000113161.113684.374305503.97140-0.579103.202102.33240K562MTPAP
HMGCRENSG00000113161.116956.400803624.683500.940408.461006.58120K562NAA15
HMGCRENSG00000113161.115044.910506405.19620-0.344404.627403.03180K562NCBP2
HMGCRENSG00000113161.118841.3753012125.19130-0.455704.140402.29660K562NOL12
HMGCRENSG00000113161.112380.626103965.13920-0.7360010.239307.55400K562NONO
HMGCRENSG00000113161.114071.979906114.71850-0.586606.003204.96320K562NSUN2
HMGCRENSG00000113161.112800.256607137.68760-1.3499011.853109.36060K562PABPC1
HMGCRENSG00000113161.119548.235308042.610200.247502.613501.30480K562PCBP1
HMGCRENSG00000113161.115395.138207321.80620-0.440504.901203.58830K562PCBP2
HMGCRENSG00000113161.112174.246104088.63590-0.9111014.9787013.08290K562PCBP3
HMGCRENSG00000113161.116196.0189011388.97980-0.878207.926905.72240K562PNPT1
HMGCRENSG00000113161.111617.167903136.22570-0.9556025.4282023.21100K562POLR2G
HMGCRENSG00000113161.114059.960706608.64350-0.702906.292403.55450K562PPIL4
HMGCRENSG00000113161.112708.962203917.30890-0.532106.349805.21440K562PRPF8
HMGCRENSG00000113161.112944.506603619.58590-0.297802.075801.30260K562PSIP1
HMGCRENSG00000113161.113564.923207994.51610-1.1651041.2887038.86880K562PTBP1
HMGCRENSG00000113161.119819.5092012866.17390-0.389903.024701.90500K562PUM1
HMGCRENSG00000113161.118087.8172012602.31120-0.639906.972205.43140K562PUM2
HMGCRENSG00000113161.117818.474904313.093900.858105.908705.15210K562PUS1
HMGCRENSG00000113161.1110972.100506604.685200.732205.907603.73640K562RAVER1
HMGCRENSG00000113161.118206.705604203.294600.9652017.1894015.68930K562RBM15
HMGCRENSG00000113161.114249.652107666.80240-0.8513018.0442015.66910K562RBM22
HMGCRENSG00000113161.115694.896107472.89190-0.392003.782702.06870K562RBM34
HMGCRENSG00000113161.112507.455903302.26920-0.397205.277103.90090K562RCC2
HMGCRENSG00000113161.114357.653608067.84550-0.8886016.9514014.35280K562NELFE
HMGCRENSG00000113161.115339.594107027.07290-0.396205.324302.85050K562RECQL
HMGCRENSG00000113161.111539.762003990.61670-1.3739022.1605019.88390K562RPS19
HMGCRENSG00000113161.114193.569106625.59820-0.659904.927402.75010K562RPS3A
HMGCRENSG00000113161.112600.041705565.15440-1.0979016.3298013.80030K562RPS3
HMGCRENSG00000113161.112570.867804005.71670-0.639805.560203.67690K562RRP9
HMGCRENSG00000113161.111288.894202794.13080-1.1163028.7852026.07730K562SAFB
HMGCRENSG00000113161.113735.757906767.16120-0.857107.543804.94720K562SBDS
HMGCRENSG00000113161.112171.546002888.95050-0.411804.111402.31580K562SDAD1
HMGCRENSG00000113161.114992.307603352.447500.574404.383202.39330K562SERBP1
HMGCRENSG00000113161.117595.742704769.299100.671302.765401.56210K562SF1
HMGCRENSG00000113161.113807.223806034.69000-0.664503.625502.69970K562SF3A3
HMGCRENSG00000113161.111662.132103214.23970-0.951404.148202.93850K562SF3B1
HMGCRENSG00000113161.115414.055807196.90330-0.410706.615105.25690K562SF3B4
HMGCRENSG00000113161.111876.847402719.37310-0.535002.863101.57950K562SLBP
HMGCRENSG00000113161.112137.385303130.47680-0.550507.527905.59920K562SRFBP1
HMGCRENSG00000113161.112955.315403911.17820-0.404303.898401.91930K562SRP68
HMGCRENSG00000113161.113806.696107837.08230-1.0418033.9570031.51800K562SRSF1
HMGCRENSG00000113161.113404.734205372.95800-0.6582013.3622010.89870K562SRSF4
HMGCRENSG00000113161.115440.640707401.01710-0.443905.366103.81600K562SRSF5
HMGCRENSG00000113161.112199.667703793.51080-0.786208.766706.90820K562SUPV3L1
HMGCRENSG00000113161.111622.146603145.57430-0.9554026.1665023.85420K562SYNCRIP
HMGCRENSG00000113161.114641.878807932.08850-0.7730013.6174011.82130K562TARDBP
HMGCRENSG00000113161.112217.102503457.59690-0.641107.473404.90020K562TFIP11
HMGCRENSG00000113161.114604.547907651.27690-0.7326017.7405015.51560K562TIA1
HMGCRENSG00000113161.112745.522203481.45250-0.342602.716301.78920K562TIAL1
HMGCRENSG00000113161.114629.336805679.62570-0.295005.661803.81510K562TROVE2
HMGCRENSG00000113161.112578.888304014.60920-0.638508.387806.54080K562UCHL5
HMGCRENSG00000113161.112487.838406483.62020-1.3819020.1314018.39950K562UPF1
HMGCRENSG00000113161.118243.462504374.046200.914205.283203.31360K562UTP18
HMGCRENSG00000113161.113076.866605769.61680-0.9070010.423208.90290K562WDR43
HMGCRENSG00000113161.112399.138704087.43470-0.7687011.760708.94640K562XRN2
HMGCRENSG00000113161.117534.1363011115.54880-0.561103.304402.35130K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for HMGCR is not available on ENCORE database.





20 RBPs can affect the splicing of HMGCR :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEHMGCRENSG00000113161.11chr5+746508807465103974650327746505227465118974651347-0.083000.000000.00049excludedK562IGF2BP2
SEHMGCRENSG00000113161.11chr5+746508807465103974650327746505227465118974651347-0.079000.000040.00147excludedK562SRSF1
SEHMGCRENSG00000113161.11chr5+746400477464015774639677746397897464139874641483-0.076000.000020.00068excludedK562SF3B4
SEHMGCRENSG00000113161.11chr5+746508807465103974650327746505227465118974651347-0.053000.004070.06329excludedK562SF3B4
SEHMGCRENSG00000113161.11chr5+746508807465103974650327746505227465118974651347-0.116000.000020.00153excludedK562PRPF8
SEHMGCRENSG00000113161.11chr5+746508807465103974650327746505227465118974651347-0.218000.000000.00001excludedK562XRCC6
SEHMGCRENSG00000113161.11chr5+746552227465533674654915746551357465580974655964-0.057000.000040.00083excludedK562AQR
SEHMGCRENSG00000113161.11chr5+746472817464742774647104746471407465032774650522-0.068000.000000.00004excludedK562AQR
SEHMGCRENSG00000113161.11chr5+746521677465223674651137746513477465448174654652-0.073000.000050.00092excludedK562AQR
SEHMGCRENSG00000113161.11chr5+746400697464015774639677746397897464139874641483-0.078000.000000.00000excludedK562AQR
SEHMGCRENSG00000113161.11chr5+746508807465103974650327746505227465118974651347-0.113000.000000.00000excludedK562AQR
SEHMGCRENSG00000113161.11chr5+746508807465103974650327746505227465118974651347-0.052000.001690.05915excludedK562FXR1
SEHMGCRENSG00000113161.11chr5+746400697464015774639677746397897464139874641483-0.054000.000260.00540excludedK562PUS1
SEHMGCRENSG00000113161.11chr5+746508807465103974650327746505227465118974651347-0.117000.000000.00000excludedK562KHSRP
SEHMGCRENSG00000113161.11chr5+746508807465103974650327746505227465118974651347-0.079000.000010.00337excludedK562RBM22
SEHMGCRENSG00000113161.11chr5+746508807465103974650327746505227465118974651347-0.067000.000040.00262excludedK562TARDBP
SEHMGCRENSG00000113161.11chr5+746508807465103974650327746505227465118974651347-0.101000.000000.00032excludedHepG2HNRNPC
SEHMGCRENSG00000113161.11chr5+746508807465103974650327746505227465118974651347-0.156000.000000.00180excludedK562EIF3G
SEHMGCRENSG00000113161.11chr5+746508807465103974650327746505227465118974651347-0.106000.000030.01302excludedK562SERBP1
SEHMGCRENSG00000113161.11chr5+746508807465103974650327746505227465118974651347-0.169000.000000.00000excludedK562PTBP1
A3SSHMGCRENSG00000113161.11chr5+746472487464742774647341746474277464689274647140-0.074000.000610.06491shorterK562EFTUD2
A3SSHMGCRENSG00000113161.11chr5+746472487464742774647341746474277464689274647140-0.089000.000080.02583shorterK562SUPV3L1
A3SSHMGCRENSG00000113161.11chr5+746472487464742774647341746474277464689274647140-0.078000.000000.00000shorterHepG2U2AF2
A3SSHMGCRENSG00000113161.11chr5+7465214574652236746521677465223674651189746513470.121000.000000.00000longerK562AQR
A3SSHMGCRENSG00000113161.11chr5+7465444674654652746544817465465274652133746522730.081000.000000.00000longerK562AQR
A3SSHMGCRENSG00000113161.11chr5+7465113774651347746511897465134774650327746505220.215000.002090.01338longerK562AQR
A3SSHMGCRENSG00000113161.11chr5+746472487464742774647341746474277464710474647140-0.052000.000050.00048shorterK562AQR
A5SSHMGCRENSG00000113161.11chr5+7464737874647592746473787464742774650327746504880.052000.000000.00000longerK562AQR
A5SSHMGCRENSG00000113161.11chr5+746384077463859574638407746385457463967774639855-0.052000.000000.00003shorterK562AQR
RIHMGCRENSG00000113161.11chr5+746468927464743574646892746471407464734174647435-0.089000.000010.00020excludedHepG2U2AF2
RIHMGCRENSG00000113161.11chr5+7464689274647435746468927464714074647341746474350.092000.000240.05184includedHepG2XPO5
RIHMGCRENSG00000113161.11chr5+746468927464743574646892746471407464734174647435-0.078000.000590.02883excludedK562SUPV3L1
RIHMGCRENSG00000113161.11chr5+746468927464743574646892746471407464734174647435-0.073000.000010.00034excludedHepG2FUBP3
RIHMGCRENSG00000113161.11chr5+746468927464743574646892746471407464734174647435-0.078000.001260.01497excludedK562EFTUD2
MXEHMGCRENSG00000113161.11chr5+74647026746471407464724874647427746466137464677474650327746505220.060000.000000.000001includedK562AQR
MXEHMGCRENSG00000113161.11chr5+74647026746471407464719074647427746466137464677474650327746505220.060000.000000.000001includedK562AQR
MXEHMGCRENSG00000113161.11chr5+74647026746471407464734174647427746466137464677474650327746505220.064000.000000.000001includedK562AQR
MXEHMGCRENSG00000113161.11chr5+7463840774638595746396157463978974633056746331257464139874641483-0.067000.000000.000002includedK562AQR
MXEHMGCRENSG00000113161.11chr5+7464728174647427746474747464759274647104746471407465032774650522-0.068000.000000.000002includedK562AQR
MXEHMGCRENSG00000113161.11chr5+7464734174647427746474747464759274647104746471407465032774650522-0.070000.000000.000002includedK562AQR
MXEHMGCRENSG00000113161.11chr5+7464737874647427746474747464759274647104746471407465032774650522-0.087000.000000.000002includedK562AQR
MXEHMGCRENSG00000113161.11chr5+7464724874647427746503277465052274646892746471407465118974651347-0.079000.000000.000892includedK562XRCC6

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for HMGCR is not avaliable on ENCORE database.