FASTKD1

General Information

Gene Name : FASTKD1
Gene ID : ENSG00000138399.17
Essential Gene : No

Functions

Not Available

Localization(RBPImage: FASTKD1)

Nuclei
Nucleoplasm
Mutually Exclusive from Nucleolus
Speckles
Cytoplasm
Cytosolic

Domains (AlphaFold: FASTKD1)

No checked domain (RRM, ZNF, KH, Helicase, Nuclease, dRBM or PUM_HD)

Antibody Validation

GeneTex: GTX107835

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	FASTKD1	ENSG00000138399.17	37.65	41.08	39.36	ENCSR000AEF
HepG2	FASTKD1	ENSG00000138399.17	11.86	30.32	21.09	ENCSR985KAT
K562	FASTKD1	ENSG00000138399.17	60.39	60.44	60.41	ENCSR000AEO

Assays

1 Released experiments are available on ENCORE database.

Assay Type	Exp_Name	ENCODE ID	Target label	Biosample	Status	Linked Antibody	Controls	Method	Note
knockdown followed by RNA-seq	FASTKD1-BGHLV22-HepG2	ENCSR728BOL	FASTKD1	HepG2	Released		ENCSR279HMU	shRNA	KD% = 0,0.0

eCLIP

No eCLIP experiment available

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	Phosphate	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
FASTKD1	ENCAB421NRI	GTX107835	40009			Released, ENCODE3

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project
FASTKD1	K562	shRNA			BGKLV24-27,BGKLV24-28	BGKLV24-1,BGKLV24-2	redo transduction,redo transduction	NotSatisfied	ENCODE3
FASTKD1	K562	shRNA			BGKLV28-15,BGKLV28-16	BGKLV28-1,BGKLV28-2	21.8,0.0	NotSatisfied	ENCODE3
FASTKD1	HepG2	shRNA	ENCSR728BOL	ENCSR279HMU	FASTKD1-BGHLV22-15_17752,FASTKD1-BGHLV22-16_17753	non-target-BGHLV22-1_17746,non-target-BGHLV22-2_17747	0,0.0	Released	ENCODE3
FASTKD1	K562	CRISPR			BGKcLV11-51,BGKcLV11-52	BGKcLV11-1,BGKcLV11-2	0.0,0.0	NotSatisfied	ENCODE4
FASTKD1	K562	CRISPR			BGKcLV11-53,BGKcLV11-54	BGKcLV11-1,BGKcLV11-2	0.0,0.0	NotSatisfied	ENCODE4
FASTKD1	HepG2	CRISPR			BGHcLV12-39,BGHcLV12-40	BGHcLV12-1,BGHcLV12-2	0.0,0.0	NotSatisfied	ENCODE4
FASTKD1	HepG2	CRISPR			BGHcLV12-41,BGHcLV12-42	BGHcLV12-1,BGHcLV12-2		NotSatisfied	ENCODE4

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

FASTKD1: Click to RBP Image Database

Nuclei

Nucleoplasm

Mutually Exclusive from Nucleolus

Speckles

Cytoplasm

Cytosolic

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
FASTKD1	Product_ID: GTX107835 Lot_ID: 40009 Source: GeneTex Target Name: FASTKD1-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for FASTKD1 is not avaliable on ENCORE database.

Proteins bound to RNA

FASTKD1 RNA is bound by 16 proteins.

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eCLIP assay for FASTKD1 is not avaliable on ENCORE database.

16 proteins are bound to FASTKD1 RNA:

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Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr2	170386335	170386400	-	3'-UTR,CDS,intron-Distal,intron-Proximal	4.93448	14.39081	K562	PUM2
chr2	170413700	170413795	-	CDS,intron-Distal	4.05437	12.80995	HepG2	BCLAF1
chr2	170425699	170425769	-	5'-UTR,CDS,intron-Distal,intron-Proximal	4.61779	12.77719	K562	U2AF2
chr2	170396610	170396690	-	CDS,intron-Distal,intron-Proximal	3.72255	9.20168	K562	ZC3H11A
chr2	170425709	170425768	-	5'-UTR,CDS,intron-Distal,intron-Proximal	4.30820	8.53087	K562	U2AF1
chr2	170414795	170414844	-	intron-Distal	4.26677	8.21270	K562	XRCC6
chr2	170403089	170403172	-	CDS,intron-Distal	3.40111	8.16183	HepG2	BCLAF1
chr2	170428357	170428438	-	CDS,intron-Distal	3.96434	8.11238	K562	PUM2
chr2	170414776	170414845	-	intron-Distal	4.14879	7.46637	HepG2	XPO5
chr2	170428281	170428360	-	CDS,intron-Distal	4.82537	7.08889	K562	RBM15
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 40 entries

eCLIP assay for FASTKD1 is not avaliable on ENCORE database.

Diffrential Expression

104 differentially expressed genes after Knockdown/Knockout FASTKD1 protein.

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102 RBPs can affect the levels of FASTKD1.

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104 differentially expressed genes after Knockdown/Knockout FASTKD1 protein :

Only display 100 entries as example. Please click "View All" button to see all 104 entries.

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Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
PLA2G2A	ENSG00000188257.6	47.83190	291.02290	-2.60510	22.15580	17.79770	HepG2	FASTKD1
CYP24A1	ENSG00000019186.5	95.38540	430.45620	-2.17400	20.42350	16.36630	HepG2	FASTKD1
LIPG	ENSG00000101670.7	136.51290	19.31460	2.82120	15.66080	11.77980	HepG2	FASTKD1
AREGB	ENSG00000205595.3	450.15580	1291.70540	-1.52080	15.27170	11.51560	HepG2	FASTKD1
PCSK9	ENSG00000169174.9	2305.06800	977.21240	1.23800	11.57340	7.91420	HepG2	FASTKD1
DYSF	ENSG00000135636.9	238.43490	70.07100	1.76660	11.38190	7.80180	HepG2	FASTKD1
TANC1	ENSG00000115183.9	452.55200	1073.85930	-1.24660	10.47300	6.95990	HepG2	FASTKD1
ACAT2	ENSG00000120437.7	3057.16310	1367.14120	1.16090	10.38360	6.92850	HepG2	FASTKD1
TUBA1A	ENSG00000167552.9	666.66810	1527.91540	-1.19650	10.09930	6.69540	HepG2	FASTKD1
KITLG	ENSG00000049130.9	95.59040	272.56200	-1.51160	9.38430	6.02610	HepG2	FASTKD1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 100 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

102 RBPs can affect the gene expression of FASTKD1 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
FASTKD1	ENSG00000138399.13	368.65370	830.56760	-1.17180	26.24830	25.02940	HepG2	SSB
FASTKD1	ENSG00000138399.13	1762.87860	2738.39770	-0.63540	18.18980	16.52560	K562	UPF1
FASTKD1	ENSG00000138399.13	1797.77240	2837.69080	-0.65850	15.79670	14.28990	K562	EIF2S2
FASTKD1	ENSG00000138399.13	366.03710	687.57960	-0.90950	14.51660	13.04700	HepG2	HNRNPF
FASTKD1	ENSG00000138399.13	2499.43480	4100.91630	-0.71430	12.65820	11.53490	K562	AQR
FASTKD1	ENSG00000138399.13	347.77100	681.47340	-0.97050	11.18150	9.86580	HepG2	HNRNPC
FASTKD1	ENSG00000138399.13	821.21860	500.10570	0.71540	10.26990	9.48700	HepG2	SRSF1
FASTKD1	ENSG00000138399.13	1021.91190	549.26590	0.89560	10.08910	8.96020	HepG2	DDX3X
FASTKD1	ENSG00000138399.13	384.77140	677.07070	-0.81530	9.92560	8.63670	HepG2	IGF2BP1
FASTKD1	ENSG00000138399.13	1792.03730	2548.44890	-0.50800	9.88590	8.41550	K562	SF3A3
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 121 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for FASTKD1 is not available on ENCORE database.

15 RBPs can affect the splicing of FASTKD1 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	FASTKD1	ENSG00000138399.13	chr2	-	170425693	170425762			170419734	170419860	170428162	170428681	-0.29000	0.00000	0.00000	excluded	K562	SF3B4
SE	FASTKD1	ENSG00000138399.13	chr2	-	170394522	170394651			170393736	170393850	170396560	170396634	0.19500	0.00000	0.00000	included	K562	HNRNPA1
SE	FASTKD1	ENSG00000138399.13	chr2	-	170425693	170425762			170419734	170419860	170428162	170428226	-0.27300	0.00000	0.00010	excluded	K562	EFTUD2
SE	FASTKD1	ENSG00000138399.13	chr2	-	170394522	170394651			170393736	170393850	170396560	170396689	-0.19900	0.00000	0.00019	excluded	K562	U2AF1
SE	FASTKD1	ENSG00000138399.13	chr2	-	170425693	170425762			170419734	170419860	170428162	170428226	-0.20800	0.00000	0.00030	excluded	K562	HNRNPU
MXE	FASTKD1	ENSG00000138399.13	chr2	-	170425693	170425762	170428162	170428226	170419734	170419860	170430178	170430342	0.26800	0.00000	0.00000	1included	K562	SF3B4
SE	FASTKD1	ENSG00000138399.13	chr2	-	170394522	170394651			170393740	170393850	170396560	170396689	-0.20200	0.00002	0.00070	excluded	K562	HNRNPC
MXE	FASTKD1	ENSG00000138399.13	chr2	-	170419734	170419860	170425693	170425762	170413696	170413807	170428162	170428681	-0.25100	0.00002	0.00165	2included	K562	EFTUD2
SE	FASTKD1	ENSG00000138399.13	chr2	-	170394522	170394651			170393736	170393850	170396560	170396634	0.28800	0.00003	0.00288	included	HepG2	HNRNPU
MXE	FASTKD1	ENSG00000138399.13	chr2	-	170419734	170419860	170425693	170425762	170413696	170413807	170428162	170428681	-0.18900	0.00009	0.00652	2included	K562	HNRNPU

Showing 1 to 10 of 33 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

FASTKD1

General Information

Functions

Localization(RBPImage: FASTKD1)

Domains (AlphaFold: FASTKD1)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for FASTKD1 is not avaliable on ENCORE database.

16 proteins are bound to FASTKD1 RNA:

eCLIP assay for FASTKD1 is not avaliable on ENCORE database.

Diffrential Expression

104 differentially expressed genes after Knockdown/Knockout FASTKD1 protein :

102 RBPs can affect the gene expression of FASTKD1 :

The Knockdown/knockout RNA-Seq assay for FASTKD1 is not available on ENCORE database.

15 RBPs can affect the splicing of FASTKD1 :

The Knockdown/knockout RNA-Seq assay for FASTKD1 is not avaliable on ENCORE database.