LEAP2

General Information

Gene Name       : LEAP2
Gene ID             : ENSG00000164406.7
Essential Gene : No

Functions

Localization

Domains (AlphaFold: LEAP2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878LEAP2ENSG00000164406.72.121.461.79ENCSR000AEF
HepG2LEAP2ENSG00000164406.79.006.267.63ENCSR985KAT
K562LEAP2ENSG00000164406.71.411.691.55ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for LEAP2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • LEAP2 RNA is bound by 1 proteins.  







eCLIP assay for LEAP2 is not avaliable on ENCORE database.





1 proteins are bound to LEAP2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr5132209603132209697+CDS,intron-Proximal4.285725.56912HepG2AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for LEAP2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for LEAP2 is not available on ENCORE database.

  • 135 RBPs can affect the levels of LEAP2.  








The Knockdown/knockout RNA-Seq assay for LEAP2 is not available on ENCORE database.





135 RBPs can affect the gene expression of LEAP2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
LEAP2ENSG00000164406.7108.61770229.40260-1.078604.840102.64200HepG2AARS
LEAP2ENSG00000164406.7143.47070451.73410-1.6547014.8306012.64500HepG2AATF
LEAP2ENSG00000164406.7143.12420668.55020-2.2238063.9137061.97050HepG2ACO1
LEAP2ENSG00000164406.799.132502420.18870-4.60960171.84940168.87530HepG2AKAP1
LEAP2ENSG00000164406.7342.08370919.32030-1.4262021.2305018.69030HepG2AKAP8
LEAP2ENSG00000164406.71046.786002002.50710-0.9358014.0871012.44320HepG2ASCC1
LEAP2ENSG00000164406.7519.47760635.58870-0.291001.895101.30730HepG2AUH
LEAP2ENSG00000164406.7703.16190203.386201.7895013.9273012.13680HepG2BCLAF1
LEAP2ENSG00000164406.7161.7401069.066701.227506.168505.31550HepG2BOP1
LEAP2ENSG00000164406.7343.00970197.894500.793405.833404.76770HepG2CALR
LEAP2ENSG00000164406.7198.64560296.01860-0.575502.400801.50000HepG2CCAR1
LEAP2ENSG00000164406.7127.896501148.54680-3.1668023.1976021.04710HepG2CNOT7
LEAP2ENSG00000164406.7254.4144063.404402.0044018.0781016.50460HepG2CPSF6
LEAP2ENSG00000164406.7838.62310390.753801.101705.903404.32750HepG2CPSF7
LEAP2ENSG00000164406.7381.99410200.499400.929909.187907.36120HepG2YBX3
LEAP2ENSG00000164406.797.61700502.70650-2.3645047.7836045.78840HepG2CELF1
LEAP2ENSG00000164406.7797.79170497.819000.680307.125806.08800HepG2DDX21
LEAP2ENSG00000164406.7650.50310215.328701.5949017.9821015.19190HepG2DDX27
LEAP2ENSG00000164406.7329.83320174.350000.919705.755103.84480HepG2DDX28
LEAP2ENSG00000164406.7450.393102318.36660-2.3639072.3356069.51650HepG2DDX3X
LEAP2ENSG00000164406.71059.24450405.480201.385205.384904.02020HepG2DDX5
LEAP2ENSG00000164406.71465.006501991.50390-0.443003.328902.65820HepG2DDX6
LEAP2ENSG00000164406.7588.53990189.873701.6320026.9657024.55220HepG2DHX30
LEAP2ENSG00000164406.71098.47930639.598900.7802014.9351013.62480HepG2DKC1
LEAP2ENSG00000164406.7613.44340196.855501.6397033.6123031.47230HepG2DNAJC21
LEAP2ENSG00000164406.7523.79620195.146101.4244028.7523026.86650HepG2DNAJC2
LEAP2ENSG00000164406.798.74930305.95720-1.6315013.6390011.80600HepG2EIF3D
LEAP2ENSG00000164406.7697.863402059.96970-1.5616024.2851022.40610HepG2EIF4B
LEAP2ENSG00000164406.71174.38860510.838101.2009020.9198018.85990HepG2EIF4G2
LEAP2ENSG00000164406.7125.63820273.41380-1.121809.463207.28100HepG2FAM120A
LEAP2ENSG00000164406.71849.965201003.023500.883006.102203.31230HepG2FASTKD1
LEAP2ENSG00000164406.790.80560479.61550-2.401004.477903.51570HepG2FIP1L1
LEAP2ENSG00000164406.7293.14940191.544300.613902.974101.65900HepG2FKBP4
LEAP2ENSG00000164406.7538.506801002.35870-0.8964013.1718011.51600HepG2FUBP3
LEAP2ENSG00000164406.7150.10810554.94560-1.8863013.4372011.24500HepG2FUS
LEAP2ENSG00000164406.7361.309802134.68240-2.5627082.8679079.81450HepG2FXR1
LEAP2ENSG00000164406.7341.984201980.24690-2.5337064.7323061.71100HepG2G3BP1
LEAP2ENSG00000164406.71080.314002102.26510-0.9605015.4957013.43030HepG2G3BP2
LEAP2ENSG00000164406.7118.79840272.42080-1.197308.805207.25180HepG2GEMIN5
LEAP2ENSG00000164406.7233.56600486.67760-1.059103.840302.63730HepG2GNB2L1
LEAP2ENSG00000164406.7347.5797071.866802.2738024.4361022.74560HepG2GPKOW
LEAP2ENSG00000164406.7252.316501063.40250-2.0754014.0224011.55670HepG2GRSF1
LEAP2ENSG00000164406.7250.47870522.77950-1.061507.010304.71530HepG2GTF2F1
LEAP2ENSG00000164406.7518.08770638.22130-0.300902.314301.41560HepG2HDGF
LEAP2ENSG00000164406.7394.44330972.18460-1.301404.456702.68250HepG2HNRNPA0
LEAP2ENSG00000164406.7365.69980198.741700.879706.471205.54360HepG2HNRNPA1
LEAP2ENSG00000164406.7587.45620949.25010-0.692303.010101.54470HepG2HNRNPAB
LEAP2ENSG00000164406.7745.54860221.073001.7537020.4567018.74800HepG2HNRNPC
LEAP2ENSG00000164406.7594.97470185.910401.6781011.201409.88660HepG2HNRNPF
LEAP2ENSG00000164406.71105.103402005.14200-0.8595013.7043012.26640HepG2HNRNPK
LEAP2ENSG00000164406.7815.97200492.386900.7286012.7519011.40180HepG2HNRNPL
LEAP2ENSG00000164406.7445.3423068.584402.6989039.8259037.87610HepG2HNRNPLL
LEAP2ENSG00000164406.769.33970330.63640-2.253505.067303.82170HepG2HNRNPM
LEAP2ENSG00000164406.7162.52810219.61070-0.434302.016901.48950HepG2HNRNPU
LEAP2ENSG00000164406.7367.124301001.05780-1.4472019.8011016.89500HepG2HSPD1
LEAP2ENSG00000164406.7722.63410183.069101.9808036.4084034.24190HepG2IGF2BP1
LEAP2ENSG00000164406.71060.879702012.88340-0.9240011.025509.77330HepG2IGF2BP2
LEAP2ENSG00000164406.7383.685401888.98130-2.2996020.1866017.82130HepG2IGF2BP3
LEAP2ENSG00000164406.7324.62800224.323400.533104.067303.19580HepG2ILF2
LEAP2ENSG00000164406.71662.906001119.878200.570303.827002.24250HepG2ILF3
LEAP2ENSG00000164406.7922.14650611.084600.5935010.063408.22890HepG2KIF1C
LEAP2ENSG00000164406.7283.591301000.24080-1.8185026.7670023.22980HepG2KRR1
LEAP2ENSG00000164406.7149.77720476.61950-1.670008.683006.78610HepG2LARP7
LEAP2ENSG00000164406.71090.402802135.42750-0.9697014.9567013.48710HepG2MAGOH
LEAP2ENSG00000164406.7195.46970403.81940-1.046804.660202.61770HepG2MARK2
LEAP2ENSG00000164406.7335.103202147.38420-2.6799077.9580075.07080HepG2MATR3
LEAP2ENSG00000164406.784.15660320.22470-1.9279012.0997010.04620HepG2METAP2
LEAP2ENSG00000164406.7117.26440387.72830-1.725303.827902.88070HepG2MSI2
LEAP2ENSG00000164406.7317.1167069.962702.1803017.6811015.27320HepG2MTPAP
LEAP2ENSG00000164406.7867.01930325.682401.412507.934805.91480HepG2NAA15
LEAP2ENSG00000164406.7785.494602197.97110-1.4845031.1067029.16680HepG2NCBP2
LEAP2ENSG00000164406.7805.72660431.001300.902505.556703.54120HepG2NIP7
LEAP2ENSG00000164406.7295.06490535.99350-0.8612010.021908.60050HepG2NOL12
LEAP2ENSG00000164406.7253.6809060.818402.0603017.8789016.17430HepG2NSUN2
LEAP2ENSG00000164406.746.69820217.36500-2.2187022.2524020.30190HepG2PARN
LEAP2ENSG00000164406.7523.980701944.25740-1.8916097.8746095.24040HepG2PCBP1
LEAP2ENSG00000164406.7269.18230525.37370-0.964805.416903.99980HepG2PCBP2
LEAP2ENSG00000164406.71022.01070635.736400.684803.146901.30910HepG2PES1
LEAP2ENSG00000164406.71042.65670457.635501.1879013.9093010.77560HepG2PHF6
LEAP2ENSG00000164406.7644.63120195.873501.7185015.5202013.85170HepG2PPIL4
LEAP2ENSG00000164406.7570.03250292.174300.964107.871706.65320HepG2PRPF4
LEAP2ENSG00000164406.7307.73540552.33240-0.843803.685902.28590HepG2PRPF6
LEAP2ENSG00000164406.7629.557501978.39650-1.6519076.6773074.73350HepG2PTBP1
LEAP2ENSG00000164406.7719.54340511.652100.491803.994403.29320HepG2PUF60
LEAP2ENSG00000164406.7138.14360543.14050-1.9752045.4672043.66120HepG2PUM1
LEAP2ENSG00000164406.797.23410542.74420-2.4807048.8574046.35840HepG2PUM2
LEAP2ENSG00000164406.71621.572202142.56280-0.401905.265604.44440HepG2QKI
LEAP2ENSG00000164406.7349.25580507.10600-0.538002.084301.46480HepG2RAVER1
LEAP2ENSG00000164406.7141.28530609.90100-2.1100019.7352018.61240HepG2RBM22
LEAP2ENSG00000164406.71555.140101944.54730-0.322402.980702.28440HepG2RBM25
LEAP2ENSG00000164406.7176.00720574.69410-1.707208.136306.43060HepG2RBM27
LEAP2ENSG00000164406.7929.84960505.316900.879706.797203.63690HepG2RBM34
LEAP2ENSG00000164406.7668.070402201.73050-1.7206085.3336083.40410HepG2NELFE
LEAP2ENSG00000164406.7797.998102050.67600-1.3616057.1287055.11140HepG2RECQL
LEAP2ENSG00000164406.7806.04350200.265302.0088042.4553040.53440HepG2RPLP0
LEAP2ENSG00000164406.7797.49130497.935200.679404.218903.05820HepG2RPS10
LEAP2ENSG00000164406.762.43430297.69330-2.2534026.5923025.01020HepG2RPS19
LEAP2ENSG00000164406.7743.647101154.25340-0.634302.483301.72400HepG2RPS3A
LEAP2ENSG00000164406.7312.13640541.03250-0.793503.253102.08140HepG2RPS5
LEAP2ENSG00000164406.755.81940175.64120-1.653808.706607.41790HepG2RRP9
LEAP2ENSG00000164406.7808.24060195.567402.0470065.4657063.04390HepG2SAFB2
LEAP2ENSG00000164406.7427.1689067.880902.6536036.7368034.54500HepG2SF3B1
LEAP2ENSG00000164406.71148.471602059.69090-0.8427024.2181022.76330HepG2SF3B4
LEAP2ENSG00000164406.771.69470352.46400-2.297503.257701.66640HepG2SFPQ
LEAP2ENSG00000164406.71437.39370490.593001.5508068.3848065.98340HepG2SLBP
LEAP2ENSG00000164406.71239.14940494.575301.325008.466505.91820HepG2SLTM
LEAP2ENSG00000164406.7132.09250228.05510-0.787805.263704.42520HepG2SMN1
LEAP2ENSG00000164406.7233.83170688.87680-1.5588027.3250026.17270HepG2SRFBP1
LEAP2ENSG00000164406.7326.834502149.90210-2.71760181.88450179.63780HepG2SRSF1
LEAP2ENSG00000164406.7181.35510505.18100-1.4780024.6017023.00340HepG2SRSF5
LEAP2ENSG00000164406.7746.98860182.649502.0319058.4455056.18780HepG2SRSF7
LEAP2ENSG00000164406.71254.016301749.08630-0.480005.820205.07200HepG2SRSF9
LEAP2ENSG00000164406.71123.51920598.136300.9094021.7547020.61510HepG2SSB
LEAP2ENSG00000164406.7496.74720997.31880-1.0055011.896709.51880HepG2SSRP1
LEAP2ENSG00000164406.7817.68300319.947501.3536010.539808.34230HepG2STAU1
LEAP2ENSG00000164406.7846.25970473.873200.836505.756204.03310HepG2SUB1
LEAP2ENSG00000164406.7149.56270574.53070-1.9416043.3211041.38200HepG2SUCLG1
LEAP2ENSG00000164406.7991.81880323.481101.6163012.2175010.37230HepG2SUPT6H
LEAP2ENSG00000164406.7366.80750229.086300.679003.740402.97090HepG2SUPV3L1
LEAP2ENSG00000164406.71667.294401932.50110-0.213001.937901.45430HepG2TAF15
LEAP2ENSG00000164406.7301.9187066.867402.1747023.3155021.60440HepG2TARDBP
LEAP2ENSG00000164406.7203.14880979.59600-2.2696022.9374020.35150HepG2TBRG4
LEAP2ENSG00000164406.7132.18820213.35680-0.690702.431601.95760HepG2TIAL1
LEAP2ENSG00000164406.7286.03190509.01230-0.831504.343102.52500HepG2TRA2A
LEAP2ENSG00000164406.7268.26150499.86110-0.897908.975907.23670HepG2TUFM
LEAP2ENSG00000164406.7186.71520410.02870-1.134902.177501.61360HepG2U2AF1
LEAP2ENSG00000164406.7121.71900377.09000-1.631402.304501.41480HepG2U2AF2
LEAP2ENSG00000164406.7955.45290529.094300.852608.081706.62280HepG2UBE2L3
LEAP2ENSG00000164406.7506.37550209.803001.2711010.238208.24780HepG2UPF2
LEAP2ENSG00000164406.7254.13230456.89590-0.846309.314407.53000HepG2UTP18
LEAP2ENSG00000164406.7154.31050557.57730-1.8533012.9607010.86500HepG2XRCC6
LEAP2ENSG00000164406.7697.80530225.510001.6295022.7303020.74400HepG2XRN2
LEAP2ENSG00000164406.7171.4769099.821100.780502.676302.09660K562AQR
LEAP2ENSG00000164406.776.3490037.178801.038002.814002.20450K562FXR1
LEAP2ENSG00000164406.7105.4230037.331701.497605.744304.91480K562HNRNPC
LEAP2ENSG00000164406.720.1183047.34040-1.234602.249701.35330K562IGF2BP2
LEAP2ENSG00000164406.723.2030048.35890-1.059502.233201.62650K562PTBP1
LEAP2ENSG00000164406.733.6780074.45140-1.144503.282201.89280K562TROVE2
LEAP2ENSG00000164406.770.82540112.47150-0.667202.139801.39140K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for LEAP2 is not available on ENCORE database.






No RBPs affect the alternative splcing events of LEAP2 on ENCORE database.





The Knockdown/knockout RNA-Seq assay for LEAP2 is not avaliable on ENCORE database.