DDX28

General Information

Gene Name       : DDX28
Gene ID             : ENSG00000182810.6
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: DDX28)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878DDX28ENSG00000182810.69.029.889.45ENCSR000AEF
HepG2DDX28ENSG00000182810.610.148.769.45ENCSR985KAT
K562DDX28ENSG00000182810.611.199.1910.19ENCSR000AEO

Assays

2 Released experiments are available on ENCORE database.

Assay TypeExp_NameENCODE IDTarget labelBiosampleStatusLinked AntibodyControlsMethodNote
knockdown followed by RNA-seq DDX28-BGKLV19-K562ENCSR205VSQDDX28K562ReleasedENCSR661HEL   shRNAKD% = ,no band
knockdown followed by RNA-seq DDX28-BGHLV17-HepG2ENCSR222CSFDDX28HepG2ReleasedENCSR856ZRV   shRNAKD% = ,






  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
DDX28K562shRNAENCSR205VSQENCSR661HELDDX28_BGKLV19_13B,DDX28_BGKLV19_14BNT_BGKLV19_1B,NT_BGKLV19_2B,no bandReleasedENCODE3
DDX28HepG2shRNAENCSR222CSFENCSR856ZRVDDX28_BGHLV17_55,DDX28_BGHLV17_56NT_BGHLV17_63,NT_BGHLV17_64,ReleasedENCODE3


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for DDX28 is not avaliable on ENCORE database.



Proteins bound to RNA
  • DDX28 RNA is bound by 1 proteins.  







eCLIP assay for DDX28 is not avaliable on ENCORE database.





1 proteins are bound to DDX28 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr166805576468055846-CDS4.513754.86150HepG2RBM15
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for DDX28 is not avaliable on ENCORE database.



Diffrential Expression
  • 1,085 differentially expressed genes after Knockdown/Knockout DDX28 protein.  





  • 81 RBPs can affect the levels of DDX28.  







1,085 differentially expressed genes after Knockdown/Knockout DDX28 protein :

Only display 100 entries as example. Please click "View All" button to see all 1,085 entries.     

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
CYP51A1ENSG00000001630.113949.918403126.710100.337103.232601.72330HepG2DDX28
TFPIENSG00000003436.107169.739004131.291500.7952013.9103011.33250HepG2DDX28
ITGA3ENSG00000005884.1343.85250123.81300-1.497406.741704.71820HepG2DDX28
ZFXENSG00000005889.11657.35310487.539300.431003.258301.74620HepG2DDX28
PAFAH1B1ENSG00000007168.81042.543501532.99300-0.556204.825903.02510HepG2DDX28
ST3GAL1ENSG00000008513.10451.68740698.48600-0.628905.058903.23440HepG2DDX28
UBE3CENSG00000009335.13610.00700955.02050-0.646706.317704.33830HepG2DDX28
CD9ENSG00000010278.776.22980128.40470-0.752302.913201.48360HepG2DDX28
NCAPD2ENSG00000010292.81812.215502763.38250-0.608707.234105.15460HepG2DDX28
ANLNENSG00000011426.61280.781201832.11830-0.516504.373102.64350HepG2DDX28
PSMC4ENSG00000013275.3968.761901341.10080-0.469203.941302.28350HepG2DDX28
CLDN11ENSG00000013297.666.15150135.08620-1.030004.628702.86050HepG2DDX28
MVPENSG00000013364.14372.20260550.55930-0.564803.322501.79260HepG2DDX28
CLK1ENSG00000013441.111217.82480858.373200.504504.184402.48550HepG2DDX28
ZMYND11ENSG00000015171.14497.55330816.74480-0.715006.117704.15270HepG2DDX28
DPEP1ENSG00000015413.579.96650162.36190-1.021702.714901.34080HepG2DDX28
CHDHENSG00000016391.62168.655501634.149600.408202.957501.51750HepG2DDX28
SLC38A5ENSG00000017483.10323.80210593.17760-0.873407.980405.81190HepG2DDX28
RALBP1ENSG00000017797.7571.27050744.91240-0.382902.684901.31890HepG2DDX28
SAMD4AENSG00000020577.9437.91620640.51140-0.548603.496001.92460HepG2DDX28
ZNF839ENSG00000022976.11253.58590158.265000.680002.922301.49170HepG2DDX28
SNAPC1ENSG00000023608.472.68780153.49450-1.078402.955601.51650HepG2DDX28
HSD17B6ENSG00000025423.751.4607013.651601.914303.658602.05140HepG2DDX28
TOMM34ENSG00000025772.7683.986301022.41240-0.579905.679903.77730HepG2DDX28
HMGB3ENSG00000029993.10590.79020877.74390-0.571204.166702.47160HepG2DDX28
FUT8ENSG00000033170.12286.44500468.38860-0.709405.331903.46730HepG2DDX28
UHRF1ENSG00000034063.9771.534601061.74490-0.460603.712502.09110HepG2DDX28
SH3YL1ENSG00000035115.17581.03990383.523200.599204.353202.62770HepG2DDX28
FAM136AENSG00000035141.31743.159001303.789200.418903.682302.06830HepG2DDX28
CDH1ENSG00000039068.14789.87260532.838400.567804.943003.12990HepG2DDX28
C6ENSG00000039537.938.7160012.978001.576802.858501.44350HepG2DDX28
SPDL1ENSG00000040275.12350.62550494.17950-0.495102.820801.41760HepG2DDX28
AIFM2ENSG00000042286.10446.63870722.36600-0.693604.876503.06710HepG2DDX28
FAM214AENSG00000047346.8351.43380230.331100.609403.159701.66890HepG2DDX28
MAP4ENSG00000047849.172282.141602973.53190-0.381803.271101.75470HepG2DDX28
USP28ENSG00000048028.7334.79550519.59920-0.634103.428001.87210HepG2DDX28
RCN1ENSG00000049449.4564.88340918.32750-0.701105.973004.02700HepG2DDX28
ARID1BENSG00000049618.17926.243301199.53940-0.373002.769401.37830HepG2DDX28
JKAMPENSG00000050130.13310.46880578.02750-0.896704.649102.87970HepG2DDX28
FAM160A2ENSG00000051009.6388.79380245.618700.662503.640902.04010HepG2DDX28
HERPUD1ENSG00000051108.101150.05240872.148600.399002.851001.43940HepG2DDX28
FNIP2ENSG00000052795.8873.80310585.767500.576904.549802.79480HepG2DDX28
TAB2ENSG00000055208.13774.028201247.58810-0.688707.136905.07320HepG2DDX28
PCGF2ENSG00000056661.9548.81180832.22490-0.600703.081001.60650HepG2DDX28
DCBLD2ENSG00000057019.111959.524203249.91820-0.729906.449504.45720HepG2DDX28
PKP2ENSG00000057294.9425.06310581.84940-0.453002.708101.33630HepG2DDX28
ATG5ENSG00000057663.8199.76490380.85610-0.930906.746804.71930HepG2DDX28
PITHD1ENSG00000057757.5151.23260293.63990-0.957306.023604.06560HepG2DDX28
ALDH18A1ENSG00000059573.42380.581003715.07610-0.642108.463406.23450HepG2DDX28
TARBP1ENSG00000059588.51244.20740964.217800.367702.735401.35440HepG2DDX28
SLC2A3ENSG00000059804.112346.277608741.02130-1.8974056.2932052.53930HepG2DDX28
MPC1ENSG00000060762.141230.83320843.635600.544804.389802.65580HepG2DDX28
EIF4BENSG00000063046.135652.419908262.41820-0.547705.950304.00930HepG2DDX28
CDONENSG00000064309.10220.24810349.27740-0.665204.036902.36670HepG2DDX28
CTSAENSG00000064601.121877.822303439.76200-0.8732014.6740012.04230HepG2DDX28
BTBD1ENSG00000064726.5686.62920928.51470-0.435402.681901.31800HepG2DDX28
MYLKENSG00000065534.14438.65860680.72380-0.634005.171803.32640HepG2DDX28
TIE1ENSG00000066056.932.0918092.16550-1.522005.263403.40990HepG2DDX28
ARFGEF1ENSG00000066777.4594.35270882.30820-0.570004.085702.41010HepG2DDX28
ACSM2BENSG00000066813.10209.25160127.511100.714503.124901.64070HepG2DDX28
PFKPENSG00000067057.1219.2152050.85320-1.404102.699401.32890HepG2DDX28
PKMENSG00000067225.1312686.3903016221.07820-0.354603.030001.57060HepG2DDX28
ERLEC1ENSG00000068912.92128.677401581.165400.428904.179802.48280HepG2DDX28
NUCKS1ENSG00000069275.122876.823804594.53840-0.675408.425906.20670HepG2DDX28
TGFBR3ENSG00000069702.61741.545503902.48640-1.1640023.1742020.18000HepG2DDX28
NEDD4ENSG00000069869.11330.49220497.79520-0.590903.535901.95740HepG2DDX28
MAPK6ENSG00000069956.73506.061902797.215900.325802.714801.34080HepG2DDX28
FSTL3ENSG00000070404.5119.99300281.34930-1.229407.952105.79200HepG2DDX28
NCK2ENSG00000071051.9176.32970262.74850-0.575402.792701.39430HepG2DDX28
VASH1ENSG00000071246.614.8869048.73610-1.710903.345901.81210HepG2DDX28
RDH11ENSG00000072042.82162.010801658.978100.382003.393801.84540HepG2DDX28
TFRCENSG00000072274.811621.076208767.128400.406504.554802.79770HepG2DDX28
AFF4ENSG00000072364.8940.213601722.01190-0.8730011.170908.72340HepG2DDX28
RHOBTB1ENSG00000072422.12753.391201250.64010-0.731208.012105.83800HepG2DDX28
MCM2ENSG00000073111.91311.976901678.30760-0.355303.005401.55200HepG2DDX28
NSFENSG00000073969.14801.769701065.27810-0.410002.986001.53800HepG2DDX28
TEAD2ENSG00000074219.9180.54810268.57760-0.573002.782501.38860HepG2DDX28
SLC24A1ENSG00000074621.9480.30300328.641900.547303.482101.91430HepG2DDX28
ENO1ENSG00000074800.924894.5403034351.04240-0.464504.669902.89490HepG2DDX28
FSCN1ENSG00000075618.13205.38160769.14990-1.905005.468603.58680HepG2DDX28
DLG1ENSG00000075711.16830.360401159.60190-0.481803.080501.60650HepG2DDX28
MCM6ENSG00000076003.4442.66040725.58300-0.712905.731603.82280HepG2DDX28
UNGENSG00000076248.6839.088901096.18320-0.385603.019601.56310HepG2DDX28
SPAG5ENSG00000076382.12922.440701494.47160-0.696107.777005.63560HepG2DDX28
MCAMENSG00000076706.10389.40590654.46540-0.749006.653104.63960HepG2DDX28
MBNL3ENSG00000076770.105842.364608206.91810-0.490303.446001.88590HepG2DDX28
DNAJC10ENSG00000077232.123572.020202632.571900.440204.719802.93670HepG2DDX28
SNRPAENSG00000077312.4525.16150719.09400-0.453403.285501.76520HepG2DDX28
C12orf5ENSG00000078237.4323.17110206.506100.646003.208101.70520HepG2DDX28
NRD1ENSG00000078618.151464.828901912.55680-0.384803.040301.57730HepG2DDX28
VDAC3ENSG00000078668.91083.031301434.24230-0.405202.898801.47330HepG2DDX28
PCM1ENSG00000078674.133748.621902867.783500.386303.954902.29530HepG2DDX28
SCGNENSG00000079689.9451.97440157.673901.5192015.4436012.79530HepG2DDX28
SMARCA2ENSG00000080503.15413.99930576.18530-0.476902.770701.37830HepG2DDX28
DLGAP4ENSG00000080845.13598.98550829.31030-0.469403.462401.89890HepG2DDX28
AFPENSG00000081051.3138249.4792073613.139000.9091018.7239015.91200HepG2DDX28
RNF13ENSG00000082996.15573.60740405.437200.500503.330201.79910HepG2DDX28
TNPO1ENSG00000083312.131598.883202335.79750-0.546905.329303.46620HepG2DDX28
CYLDENSG00000083799.13461.48470309.587400.575803.017101.56150HepG2DDX28
HALENSG00000084110.6468.14530135.746101.7859012.063409.55870HepG2DDX28
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





81 RBPs can affect the gene expression of DDX28 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
DDX28ENSG00000182810.5368.96360220.074300.745404.317003.15980HepG2ABCF1
DDX28ENSG00000182810.5258.26490192.711400.422302.124601.57730HepG2ACO1
DDX28ENSG00000182810.5362.31430230.980800.649403.152902.59000HepG2AKAP1
DDX28ENSG00000182810.5296.03440191.111900.631203.134802.29860HepG2ASCC1
DDX28ENSG00000182810.5251.13900165.628100.600402.212401.37790HepG2BCCIP
DDX28ENSG00000182810.5308.98000178.113800.794605.085604.30470HepG2BOP1
DDX28ENSG00000182810.5263.43400192.660200.451302.420101.78970HepG2CKAP4
DDX28ENSG00000182810.5174.5649098.893500.819702.826502.05300HepG2CNOT7
DDX28ENSG00000182810.5238.90190178.226100.422602.237701.48230HepG2DDX19B
DDX28ENSG00000182810.541.79820123.35930-1.561407.271105.18700HepG2DDX28
DDX28ENSG00000182810.5222.71370131.879400.755903.163202.18220HepG2EEF2
DDX28ENSG00000182810.5179.35370109.929700.706102.796901.68210HepG2EFTUD2
DDX28ENSG00000182810.5364.57710201.900100.852505.410404.51760HepG2EIF4A3
DDX28ENSG00000182810.5319.97790196.602900.702603.132202.40320HepG2EIF4B
DDX28ENSG00000182810.5590.39460401.720900.555405.520704.72040HepG2ETF1
DDX28ENSG00000182810.5346.67160188.305200.880407.087505.75670HepG2EWSR1
DDX28ENSG00000182810.5286.92830203.748100.493802.100401.49470HepG2FXR1
DDX28ENSG00000182810.5287.51870188.985500.605302.907202.22580HepG2G3BP1
DDX28ENSG00000182810.5309.78560200.659400.626403.214502.25290HepG2G3BP2
DDX28ENSG00000182810.5152.0969095.311900.674202.503501.65600HepG2GEMIN5
DDX28ENSG00000182810.5253.19240183.978500.460602.510601.57580HepG2HDGF
DDX28ENSG00000182810.5196.56300126.612900.634502.431001.82300HepG2HNRNPA1
DDX28ENSG00000182810.5205.35260139.899900.553602.711302.11100HepG2HNRNPU
DDX28ENSG00000182810.5352.95040192.092300.877606.074805.11160HepG2IGF2BP2
DDX28ENSG00000182810.5266.78130181.527000.555402.509101.35880HepG2LIN28B
DDX28ENSG00000182810.5482.71930203.819401.2438012.4753011.12050HepG2MAGOH
DDX28ENSG00000182810.5602.56580204.953801.5557018.4215016.90890HepG2MATR3
DDX28ENSG00000182810.5202.55870112.032300.854302.935401.85110HepG2METAP2
DDX28ENSG00000182810.5328.42290243.950600.428902.370101.66540HepG2NOL12
DDX28ENSG00000182810.5152.7013080.018000.932203.387201.61700HepG2PA2G4
DDX28ENSG00000182810.5323.74570220.614500.553203.606802.93360HepG2PCBP1
DDX28ENSG00000182810.5326.17710232.874900.486002.474301.90650HepG2PUF60
DDX28ENSG00000182810.5399.35210247.210000.691805.275304.51000HepG2PUM1
DDX28ENSG00000182810.5325.50690247.027500.397901.960601.38990HepG2PUM2
DDX28ENSG00000182810.5288.86700196.287700.557303.590902.90770HepG2PUS1
DDX28ENSG00000182810.5174.40440243.12720-0.479302.125801.56600HepG2QKI
DDX28ENSG00000182810.5346.99870208.485400.734904.101002.87570HepG2RBM27
DDX28ENSG00000182810.5171.10320104.171300.715802.900502.27350HepG2RPS19
DDX28ENSG00000182810.5178.3946099.343500.844503.369302.48660HepG2RPS3A
DDX28ENSG00000182810.5358.28030213.801100.744703.457802.70150HepG2SF3A3
DDX28ENSG00000182810.5329.09450233.720600.493602.747802.15790HepG2SF3B4
DDX28ENSG00000182810.5231.04700145.294100.669102.443501.83380HepG2SMN1
DDX28ENSG00000182810.5319.86630243.949500.390801.885401.47340HepG2SRSF1
DDX28ENSG00000182810.5329.17580229.933700.517503.321302.64670HepG2SRSF5
DDX28ENSG00000182810.5402.04550261.494800.620505.324904.51230HepG2SUCLG1
DDX28ENSG00000182810.5114.84590172.41100-0.586202.009601.38030HepG2TARDBP
DDX28ENSG00000182810.5215.31350126.014700.772702.374501.38620HepG2TBRG4
DDX28ENSG00000182810.5241.00290135.949000.825905.008604.37680HepG2TIAL1
DDX28ENSG00000182810.5317.62950227.513900.481302.498501.67190HepG2TUFM
DDX28ENSG00000182810.5281.37890194.901700.529702.981301.89880HepG2UTP18
DDX28ENSG00000182810.5258.28230183.060800.496502.267601.71390HepG2UTP3
DDX28ENSG00000182810.582.74390137.60220-0.733802.710602.14780K562AGGF1
DDX28ENSG00000182810.5588.11450426.910500.462103.461702.06400K562APOBEC3C
DDX28ENSG00000182810.5729.46280443.525800.717702.633402.05740K562AQR
DDX28ENSG00000182810.556.84210231.61950-2.0267017.7364014.14730K562DDX28
DDX28ENSG00000182810.5608.54530279.909501.1203018.7459017.19270K562DDX47
DDX28ENSG00000182810.5241.99890139.632800.793302.872901.84710K562EIF3A
DDX28ENSG00000182810.5321.78700141.503001.1852011.393009.75560K562EIF3G
DDX28ENSG00000182810.5230.91860114.779901.008405.722504.54770K562EIF4A3
DDX28ENSG00000182810.598.90400168.07690-0.765003.083902.11300K562FTO
DDX28ENSG00000182810.5319.19480119.364201.419008.486107.49830K562FXR1
DDX28ENSG00000182810.5121.75690186.09210-0.612002.357301.62280K562GPKOW
DDX28ENSG00000182810.586.61220165.51830-0.934302.662301.47360K562HNRNPA2B1
DDX28ENSG00000182810.5340.78080252.935400.430002.242001.30120K562HNRNPL
DDX28ENSG00000182810.577.04210151.95860-0.980003.166502.27960K562KIF1C
DDX28ENSG00000182810.583.62480158.88960-0.926003.369302.32790K562KRR1
DDX28ENSG00000182810.5290.88040133.094201.127909.964408.30270K562MAGOH
DDX28ENSG00000182810.5221.86380132.809900.740202.860201.92140K562MATR3
DDX28ENSG00000182810.5196.23570296.58160-0.595803.972803.09790K562NSUN2
DDX28ENSG00000182810.577.31720144.86230-0.905802.262201.38420K562PABPN1
DDX28ENSG00000182810.5340.58520211.061700.690303.982303.08240K562PRPF8
DDX28ENSG00000182810.5413.10370129.316401.6755022.2536020.44180K562PTBP1
DDX28ENSG00000182810.563.51330142.01540-1.160905.341904.61930K562PUS1
DDX28ENSG00000182810.579.24530138.35450-0.804002.331601.77960K562RBM15
DDX28ENSG00000182810.5203.57600123.947500.715703.572202.60880K562RBM22
DDX28ENSG00000182810.583.25340178.23040-1.098203.284201.57760K562RBM39
DDX28ENSG00000182810.5239.65770130.446900.877405.331203.75110K562NELFE
DDX28ENSG00000182810.5332.79340215.003700.630203.098702.23270K562RPS19
DDX28ENSG00000182810.5119.8387042.557201.493505.085503.66960K562RPS3
DDX28ENSG00000182810.5257.99140158.180900.705603.866502.57610K562SAFB
DDX28ENSG00000182810.5211.31190292.62610-0.469702.741201.93000K562SF3A3
DDX28ENSG00000182810.5105.92040176.96650-0.740502.736001.76730K562SF3B1
DDX28ENSG00000182810.554.32850152.12660-1.485505.083203.25260K562SNRNP200
DDX28ENSG00000182810.5256.92850126.783801.018907.061505.93990K562SRSF1
DDX28ENSG00000182810.582.1440041.076400.999702.387401.41980K562SRSF4
DDX28ENSG00000182810.5219.89110359.52380-0.709304.450502.79650K562STAU1
DDX28ENSG00000182810.5280.49120178.079400.655303.896302.92090K562SYNCRIP
DDX28ENSG00000182810.5199.17850128.290700.634502.807202.09540K562TARDBP
DDX28ENSG00000182810.5180.21220269.08450-0.578402.539401.69740K562WDR3
DDX28ENSG00000182810.5391.17220218.003700.843403.269301.51570K562XRCC6
DDX28ENSG00000182810.577.71650179.08210-1.204303.759301.79400K562YTHDC2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for DDX28 is not available on ENCORE database.






No RBPs affect the alternative splcing events of DDX28 on ENCORE database.





The Knockdown/knockout RNA-Seq assay for DDX28 is not avaliable on ENCORE database.