ATG5

General Information

Gene Name       : ATG5
Gene ID             : ENSG00000057663.15
Essential Gene : No

Functions

Localization

Domains (AlphaFold: ATG5)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878ATG5ENSG00000057663.1513.6512.4113.03ENCSR000AEF
HepG2ATG5ENSG00000057663.1515.8124.6120.21ENCSR985KAT
K562ATG5ENSG00000057663.1529.1228.7528.94ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for ATG5 is not avaliable on ENCORE database.



Proteins bound to RNA
  • ATG5 RNA is bound by 22 proteins.  







eCLIP assay for ATG5 is not avaliable on ENCORE database.





22 proteins are bound to ATG5 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr6106634289106634353-3'-UTR,intron-Distal5.055648.53052K562RBM15
chr6106632469106632546-3'-UTR,intron-Distal3.947413.20319K562UPF1
chr6106634184106634241-3'-UTR,intron-Distal3.946406.50633K562RBM15
chr6106634464106634522-3'-UTR,CDS,intron-Distal3.141533.08662K562YBX3
chr6106763962106764098-5'-UTR,CDS,intron-Distal,intron-Proximal3.351354.58459K562GRWD1
chr6106773276106773331-5'-UTR,intron-Distal,intron-Proximal4.428254.19412K562EFTUD2
chr6106763977106764056-5'-UTR,CDS,intron-Distal3.498584.74241K562YBX3
chr6106763963106764125-5'-UTR,CDS,intron-Distal,intron-Proximal4.062968.51432HepG2BCLAF1
chr6106773397106773532-5'-UTR,intron-Distal3.671755.56074HepG2NCBP2
chr6106773271106773348-5'-UTR,intron-Distal,intron-Proximal3.042183.20348K562PRPF8
chr6106773399106773513-5'-UTR,intron-Distal5.0516823.96170K562DDX3X
chr6106764122106764142-5'-UTR,intron-Distal,intron-Proximal3.104163.74019K562DDX3X
chr6106773279106773352-5'-UTR,intron-Distal,intron-Proximal4.313343.77360K562GTF2F1
chr6106727533106727602-CDS,intron-Distal,intron-Proximal3.255563.31745K562ZNF622
chr6106740847106740932-CDS,intron-Distal,intron-Proximal3.919625.25185K562PRPF8
chr6106727633106727699-CDS,intron-Distal,intron-Proximal3.954333.67607K562YBX3
chr6106677225106677318-intron-Distal4.4255510.04838HepG2PTBP1
chr6106649113106649211-intron-Distal4.334395.31654K562HNRNPL
chr6106741045106741134-intron-Distal,intron-Proximal3.751806.89441K562KHSRP
chr6106691083106691159-intron-Distal3.252834.52210K562KHSRP
chr6106656690106656813-intron-Distal3.290804.52210K562KHSRP
chr6106666814106666882-intron-Distal6.5991917.18337K562PTBP1
chr6106656554106656628-intron-Distal4.447863.77802HepG2U2AF2
chr6106755301106755411-intron-Distal3.578403.02234K562KHSRP
chr6106744988106745048-intron-Distal3.017773.31830K562KHSRP
chr6106641051106641121-intron-Distal5.585275.27957K562AATF
chr6106658138106658299-intron-Distal3.714105.20123K562KHSRP
chr6106650249106650339-intron-Distal,intron-Proximal3.751803.42844K562KHSRP
chr6106711602106711659-intron-Distal4.167983.89080K562EXOSC5
chr6106674761106674828-intron-Distal4.122806.11515K562PTBP1
chr6106650035106650120-intron-Distal,intron-Proximal3.890653.06150K562KHSRP
chr6106638704106638808-intron-Distal4.462405.91698K562KHSRP
chr6106699052106699171-intron-Distal4.614316.40061K562ILF3
chr6106694174106694338-intron-Distal3.214953.83345K562EIF4G2
chr6106723105106723203-intron-Distal4.735177.47576K562KHSRP
chr6106636340106636444-intron-Distal3.931033.25538K562KHSRP
chr6106715709106715761-intron-Distal3.422063.72952K562EXOSC5
chr6106713870106713913-intron-Distal5.294818.69609K562EXOSC5
chr6106649047106649106-intron-Distal3.803353.19036K562HNRNPL
chr6106716692106716772-intron-Distal4.053573.01445K562EXOSC5
chr6106666813106666880-intron-Distal3.082015.65555HepG2PTBP1
chr6106759375106759513-intron-Distal4.078033.72005K562MATR3
chr6106641034106641095-intron-Distal4.318214.00100K562TIA1
chr6106699004106699158-intron-Distal4.335774.75311K562CSTF2T
chr6106714368106714421-intron-Distal5.068458.36716K562EXOSC5
chr6106713556106713628-intron-Distal5.269508.36828K562EXOSC5
chr6106751165106751203-intron-Distal4.118213.59917K562EXOSC5
chr6106715312106715384-intron-Distal4.534544.80466K562EXOSC5
chr6106677335106677411-intron-Distal5.135803.42734K562PTBP1
chr6106751375106751514-intron-Distal3.699065.83959K562KHSRP
chr6106714281106714328-intron-Distal4.315353.01456K562EXOSC5
chr6106677223106677335-intron-Distal5.6693514.54239K562PTBP1
chr6106712742106712824-intron-Distal4.208503.59909K562EXOSC5
chr6106713423106713478-intron-Distal4.783296.41216K562EXOSC5
chr6106723251106723370-intron-Distal3.838825.61949K562KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for ATG5 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for ATG5 is not available on ENCORE database.

  • 82 RBPs can affect the levels of ATG5.  








The Knockdown/knockout RNA-Seq assay for ATG5 is not available on ENCORE database.





82 RBPs can affect the gene expression of ATG5 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
ATG5ENSG00000057663.8604.14940488.860900.305402.355701.78750HepG2ACO1
ATG5ENSG00000057663.81096.42030838.025700.387602.260401.77480HepG2AKAP1
ATG5ENSG00000057663.8539.05400840.65580-0.641108.844707.73170HepG2AUH
ATG5ENSG00000057663.8643.72400410.483600.649005.652504.83410HepG2BOP1
ATG5ENSG00000057663.8275.01410376.84550-0.454502.131701.51930HepG2CPSF6
ATG5ENSG00000057663.8598.65060717.36490-0.261002.106501.44710HepG2DAZAP1
ATG5ENSG00000057663.8233.91040429.12530-0.875406.146805.18260HepG2DDX21
ATG5ENSG00000057663.8199.76490380.85610-0.930906.746804.71930HepG2DDX28
ATG5ENSG00000057663.8597.60870467.699700.353502.643101.97980HepG2DKC1
ATG5ENSG00000057663.8413.59260662.99140-0.680804.126603.41160HepG2EIF2S1
ATG5ENSG00000057663.8508.15610732.77140-0.528102.555001.93990HepG2EIF4A3
ATG5ENSG00000057663.8511.19050739.06940-0.531803.082902.35240HepG2FXR1
ATG5ENSG00000057663.8282.33100427.18160-0.597503.321302.62470HepG2GPKOW
ATG5ENSG00000057663.8307.04200462.00230-0.589503.041201.60700HepG2HNRNPA0
ATG5ENSG00000057663.8323.85590453.66350-0.486302.798402.10150HepG2HNRNPC
ATG5ENSG00000057663.8413.09530526.02470-0.348702.366101.69910HepG2HNRNPF
ATG5ENSG00000057663.8353.17690450.66430-0.351702.303701.74570HepG2HNRNPU
ATG5ENSG00000057663.8393.33070517.98600-0.397202.492001.80370HepG2IGF2BP1
ATG5ENSG00000057663.8248.00050387.85230-0.645203.432202.54180HepG2PRPF8
ATG5ENSG00000057663.8695.17490398.800200.801604.419003.53900HepG2RAVER1
ATG5ENSG00000057663.8536.49310739.98280-0.463904.735604.06220HepG2NELFE
ATG5ENSG00000057663.8699.84170465.216800.589002.885402.19690HepG2SF3A3
ATG5ENSG00000057663.8543.43130403.509000.429402.540401.86240HepG2SF3B1
ATG5ENSG00000057663.8505.21140651.06800-0.365903.295602.54100HepG2SLBP
ATG5ENSG00000057663.81160.25110911.144600.348604.215403.63560HepG2SRFBP1
ATG5ENSG00000057663.8923.57870722.581300.354003.243602.74250HepG2SRSF1
ATG5ENSG00000057663.8331.84890441.81860-0.412903.058602.47270HepG2TRIM56
ATG5ENSG00000057663.8643.91610422.054400.609304.533603.73960HepG2U2AF1
ATG5ENSG00000057663.8440.39670702.16000-0.673004.760603.64650HepG2UBE2L3
ATG5ENSG00000057663.8533.96330398.325200.422703.367702.71930HepG2UTP3
ATG5ENSG00000057663.8625.43540453.754300.462805.022104.33950HepG2ZNF622
ATG5ENSG00000057663.81093.122301554.58080-0.508105.020403.35360K562ABCF1
ATG5ENSG00000057663.8576.82860872.74150-0.597408.093207.19300K562AGGF1
ATG5ENSG00000057663.8807.410901005.62280-0.316703.263302.21830K562BCLAF1
ATG5ENSG00000057663.8280.76830436.79400-0.637604.658903.21100K562CCAR1
ATG5ENSG00000057663.8999.047401353.62370-0.438205.675704.04260K562CPEB4
ATG5ENSG00000057663.8563.55250762.91490-0.437003.890002.60880K562CSTF2
ATG5ENSG00000057663.81863.162602586.02660-0.473006.202204.75120K562CELF1
ATG5ENSG00000057663.8682.62490881.63400-0.369103.919202.31210K562DDX27
ATG5ENSG00000057663.8539.13160834.75060-0.630705.245002.45760K562DDX28
ATG5ENSG00000057663.8588.52400833.99290-0.502906.219704.37910K562EIF2S1
ATG5ENSG00000057663.81636.468501317.565200.312603.658502.85150K562EIF2S2
ATG5ENSG00000057663.8548.60080714.37510-0.380903.254101.98110K562EIF4B
ATG5ENSG00000057663.81676.994002103.51660-0.326903.610402.54000K562EIF4G2
ATG5ENSG00000057663.8510.48540692.44350-0.439803.594802.09620K562EWSR1
ATG5ENSG00000057663.8556.75960874.87480-0.652006.302004.99370K562FMR1
ATG5ENSG00000057663.8532.88910783.88900-0.556803.969902.22300K562GEMIN5
ATG5ENSG00000057663.8669.93930987.45950-0.559707.275605.48180K562GLRX3
ATG5ENSG00000057663.8580.71240820.90810-0.499404.190903.21920K562GPKOW
ATG5ENSG00000057663.8692.870101275.51990-0.880404.944102.54700K562HNRNPA0
ATG5ENSG00000057663.8731.043101086.68110-0.571906.853705.21390K562HNRNPA1
ATG5ENSG00000057663.8796.043701330.51510-0.741103.428801.65770K562HNRNPAB
ATG5ENSG00000057663.8520.78430819.47760-0.654006.779705.88470K562HNRNPC
ATG5ENSG00000057663.8543.05050731.72560-0.430203.088101.87630K562HNRNPF
ATG5ENSG00000057663.81460.94250919.286000.668206.803505.24690K562HNRNPM
ATG5ENSG00000057663.8772.316201111.50930-0.525303.752702.48870K562IGF2BP2
ATG5ENSG00000057663.8772.631401130.71670-0.549405.881804.03440K562IGF2BP3
ATG5ENSG00000057663.8615.03940830.99020-0.434202.941201.43830K562LIN28B
ATG5ENSG00000057663.8952.421701166.24130-0.292202.259401.43280K562MATR3
ATG5ENSG00000057663.8619.93830801.30240-0.370202.710201.84470K562METAP2
ATG5ENSG00000057663.8691.867501038.17880-0.585509.192907.80650K562MTPAP
ATG5ENSG00000057663.8798.337701153.54380-0.531009.906208.61080K562NSUN2
ATG5ENSG00000057663.8605.96550806.74800-0.412902.708901.30980K562NUSAP1
ATG5ENSG00000057663.8906.997501142.06740-0.332502.832601.46830K562PCBP1
ATG5ENSG00000057663.81635.125002161.40460-0.402604.350502.59560K562PNPT1
ATG5ENSG00000057663.8461.24830734.72830-0.671705.727804.35180K562PSIP1
ATG5ENSG00000057663.82718.202402295.148400.244002.179201.45650K562PUF60
ATG5ENSG00000057663.81280.57690900.708200.507604.493003.82430K562PUS1
ATG5ENSG00000057663.81084.97350877.512700.306102.492301.92470K562RBM15
ATG5ENSG00000057663.8804.763201061.23120-0.399102.852501.45170K562RBM34
ATG5ENSG00000057663.8400.56120670.25190-0.742707.710806.04930K562RCC2
ATG5ENSG00000057663.8600.614101145.76460-0.9318013.0135010.65380K562NELFE
ATG5ENSG00000057663.8778.662001295.15070-0.734103.226501.56730K562SBDS
ATG5ENSG00000057663.8667.193501124.86100-0.753602.875601.53620K562SFPQ
ATG5ENSG00000057663.8337.85860481.15270-0.510103.419901.99960K562SLBP
ATG5ENSG00000057663.8394.46850635.39050-0.687706.100204.41340K562SRFBP1
ATG5ENSG00000057663.8820.136201166.10890-0.507808.450506.91160K562SRPK2
ATG5ENSG00000057663.8775.772001050.95730-0.438003.639902.40320K562SRSF5
ATG5ENSG00000057663.8694.76040956.35270-0.461005.289003.43080K562SSB
ATG5ENSG00000057663.8998.640801341.03580-0.425303.238601.86180K562STAU1
ATG5ENSG00000057663.8512.44650736.91010-0.524103.277402.16570K562SUPV3L1
ATG5ENSG00000057663.8705.00940563.634100.322802.243801.50330K562SYNCRIP
ATG5ENSG00000057663.8856.583201126.44300-0.395102.968402.23560K562TARDBP
ATG5ENSG00000057663.8798.380001086.55610-0.444604.400703.33090K562TIA1
ATG5ENSG00000057663.8515.32500706.69700-0.455602.845501.89600K562TIAL1
ATG5ENSG00000057663.8811.508801066.00640-0.393503.005401.85860K562TRA2A
ATG5ENSG00000057663.8428.06550750.67100-0.810308.705606.82140K562TRIM56
ATG5ENSG00000057663.8790.379901046.59320-0.405103.690202.68010K562WDR3
ATG5ENSG00000057663.8690.355501088.30540-0.6567012.7987011.13710K562WDR43
ATG5ENSG00000057663.81718.568602362.03500-0.458803.641002.14750K562WRN
ATG5ENSG00000057663.8597.30810793.89990-0.410502.509601.37530K562XRN2
ATG5ENSG00000057663.81369.082402246.70060-0.714606.332904.94150K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for ATG5 is not available on ENCORE database.





7 RBPs can affect the splicing of ATG5 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEATG5ENSG00000057663.8chr6-1067562381067563661067409021067409811067639751067641410.221000.000000.00001includedK562SRSF1
SEATG5ENSG00000057663.8chr6-106740902106740981106727535106727698106763975106764141-0.069000.000070.00118excludedK562AQR
SEATG5ENSG00000057663.8chr6-106696024106696119106649846106649964106727535106727698-0.054000.000000.00007excludedK562AQR
SEATG5ENSG00000057663.8chr6-106756238106756366106740902106740981106763975106764141-0.215000.000020.00052excludedK562PUS1
SEATG5ENSG00000057663.8chr6-106696024106696119106649846106649964106727535106727698-0.099000.000020.00075excludedK562PUS1
SEATG5ENSG00000057663.8chr6-106756238106756366106740902106740981106763975106764141-0.204000.000650.01581excludedK562U2AF1
SEATG5ENSG00000057663.8chr6-106696024106696119106649846106649964106727535106727698-0.054000.002510.04783excludedK562U2AF1
SEATG5ENSG00000057663.8chr6-1067562381067563661067409021067409811067639751067641410.111000.003030.08701includedK562HNRNPU
MXEATG5ENSG00000057663.8chr6-1067409021067409811067562381067564001067275351067277671067639751067641410.084000.010470.065721includedK562AQR
MXEATG5ENSG00000057663.8chr6-1066960241066961191067275351067277671066498461066499641067639751067641410.056000.000000.000061includedK562AQR
MXEATG5ENSG00000057663.8chr6-1066960241066961191067275351067277671066498461066499641067409021067409810.060000.000000.000031includedK562AQR
MXEATG5ENSG00000057663.8chr6-106727535106727698106740902106740981106649846106649964106763975106764141-0.325000.000000.000002includedK562AQR
MXEATG5ENSG00000057663.8chr6-106727535106727698106740902106740981106649846106649964106756238106756366-0.081000.000000.000002includedK562AQR
MXEATG5ENSG00000057663.8chr6-106727535106727767106740902106740981106649846106649964106763975106764141-0.243000.000010.000142includedK562AQR
MXEATG5ENSG00000057663.8chr6-106727535106727767106740902106740981106649846106649964106756238106756366-0.066000.000000.000022includedK562AQR
MXEATG5ENSG00000057663.8chr6-1066960241066961191067409021067409811066498461066499641067639751067641410.130000.004480.093971includedK562EFTUD2
MXEATG5ENSG00000057663.8chr6-1067409021067409811067562381067563661067275351067276981067639751067641410.145000.002230.074621includedK562HNRNPU
MXEATG5ENSG00000057663.8chr6-1067275351067276981067409021067409811066960241066961191067639751067641410.118000.002650.047761includedK562PRPF8

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for ATG5 is not avaliable on ENCORE database.