ARFGEF1

General Information

Gene Name       : ARFGEF1
Gene ID             : ENSG00000066777.8
Essential Gene : No

Functions

Localization

Domains (AlphaFold: ARFGEF1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878ARFGEF1ENSG00000066777.818.7417.4718.10ENCSR000AEF
HepG2ARFGEF1ENSG00000066777.88.3214.6211.47ENCSR985KAT
K562ARFGEF1ENSG00000066777.817.8317.6417.73ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for ARFGEF1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • ARFGEF1 RNA is bound by 25 proteins.  







eCLIP assay for ARFGEF1 is not avaliable on ENCORE database.





25 proteins are bound to ARFGEF1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr86810999668110026-3'-UTR,intron-Distal5.825275.76336K562PUM2
chr86811019968110244-3'-UTR,intron-Distal3.731763.04397HepG2TIA1
chr86811018968110251-3'-UTR,intron-Distal4.8496020.03557K562PUM2
chr86811013568110187-3'-UTR,intron-Distal5.355797.79622K562PUM2
chr86825555668255611-5'-UTR,intron-Distal,intron-Proximal3.841795.16954K562PCBP1
chr86825573068255814-5'-UTR,intron-Distal3.285517.70473HepG2DDX3X
chr86814508968145113-5'-UTR,CDS,intron-Distal,intron-Proximal4.285803.57722K562DDX24
chr86815069568150728-5'-UTR,CDS,intron-Distal3.730926.67313HepG2BCLAF1
chr86815057768150588-5'-UTR,CDS,intron-Distal,intron-Proximal3.952035.36555HepG2BCLAF1
chr86814513368145181-5'-UTR,CDS,intron-Distal,intron-Proximal3.7186910.68403HepG2BCLAF1
chr86814511568145179-5'-UTR,CDS,intron-Distal3.044825.62120K562ZNF622
chr86825553868255641-5'-UTR,intron-Distal,intron-Proximal3.756005.25426HepG2PCBP2
chr86814508968145133-5'-UTR,CDS,intron-Distal,intron-Proximal3.7000711.34372HepG2BCLAF1
chr86814047268140499-5'-UTR,CDS,intron-Distal3.819368.66838HepG2BCLAF1
chr86811546668115592-5'-UTR,CDS,intron-Distal,intron-Proximal4.5051311.16049K562KHSRP
chr86814508868145115-5'-UTR,CDS,intron-Distal,intron-Proximal4.679564.21675K562ZNF622
chr86815064268150662-5'-UTR,CDS,intron-Distal3.512874.09885HepG2BCLAF1
chr86817211768172152-CDS,intron-Distal4.891896.13315HepG2BCLAF1
chr86825540168255504-CDS,intron-Distal3.244184.94718HepG2PPIG
chr86817911068179170-CDS,intron-Distal,intron-Proximal4.8918911.99174HepG2BCLAF1
chr86821145968211500-CDS,intron-Distal,intron-Proximal3.395613.61259K562ZNF622
chr86816360068163683-CDS,intron-Distal4.966516.44794K562UCHL5
chr86825539868255450-CDS,intron-Distal,intron-Proximal3.067924.35477K562UCHL5
chr86811370768113783-CDS,intron-Distal3.144953.40321HepG2GRWD1
chr86821347968213557-CDS,intron-Distal3.632715.80880HepG2GRWD1
chr86816585268165858-CDS,intron-Distal,intron-Proximal3.687844.51739HepG2BCLAF1
chr86816570868165824-CDS,intron-Distal4.7726716.18601HepG2BCLAF1
chr86820877268208806-CDS,intron-Distal4.054106.23296HepG2BCLAF1
chr86818409468184131-CDS,intron-Distal3.737866.39464HepG2BCLAF1
chr86817204868172084-CDS,intron-Distal,intron-Proximal5.204305.68196HepG2BCLAF1
chr86820018868200232-CDS,intron-Distal,intron-Proximal4.8876911.09109HepG2BCLAF1
chr86816358968163678-CDS,intron-Distal6.6449823.34637HepG2BCLAF1
chr86817841468178441-CDS,intron-Distal5.012877.04013HepG2BCLAF1
chr86825540068255501-CDS,intron-Distal3.134957.87286K562ZNF622
chr86821357968213621-CDS,intron-Distal,intron-Proximal4.018593.00996K562BUD13
chr86816996468170017-CDS,intron-Distal,intron-Proximal3.826269.50935HepG2BCLAF1
chr86820425268204312-CDS,intron-Distal3.164345.71803K562UCHL5
chr86818964868189693-CDS,intron-Distal,intron-Proximal3.690923.90826K562ZNF622
chr86818822268188283-CDS,intron-Distal3.130117.97025HepG2BCLAF1
chr86813950368139545-CDS,intron-Distal,intron-Proximal3.530347.01246HepG2BCLAF1
chr86821348268213549-CDS,intron-Distal3.7985113.91024HepG2BCLAF1
chr86813166968131698-CDS,intron-Distal4.630113.89826HepG2BCLAF1
chr86815096968150983-CDS,intron-Distal,intron-Proximal3.252664.56058HepG2BCLAF1
chr86820420068204259-CDS,intron-Distal4.130119.80976HepG2BCLAF1
chr86811254468112592-CDS,intron-Distal,intron-Proximal3.171403.54602K562TIA1
chr86813968368139807-CDS,intron-Distal4.1870719.86037HepG2BCLAF1
chr86825539568255518-CDS,intron-Distal,intron-Proximal3.655555.35682HepG2GRWD1
chr86817031768170391-CDS,intron-Distal,intron-Proximal3.130119.00189HepG2BCLAF1
chr86818962968189693-CDS,intron-Distal,intron-Proximal4.7985117.34901HepG2BCLAF1
chr86821355468213606-CDS,intron-Distal4.587264.72838K562UCHL5
chr86817831868178367-CDS,intron-Distal3.220395.00751HepG2BCLAF1
chr86820878168208830-CDS,intron-Distal3.522403.90826K562ZNF622
chr86825526968255343-intron-Distal,intron-Proximal3.297104.61952HepG2FAM120A
chr86825524368255341-intron-Distal,intron-Proximal4.669335.89229K562EFTUD2
chr86812699368127077-intron-Distal3.919573.23532K562MATR3
chr86825506468255143-intron-Distal4.234004.75311K562CSTF2T
chr86818278568182876-intron-Distal4.910714.72162K562KHSRP
chr86824024268240325-intron-Distal3.967584.48652HepG2PTBP1
chr86812386068123905-intron-Distal,intron-Proximal5.227755.90023K562SF3B4
chr86812604268126105-intron-Distal3.770023.16028HepG2SUGP2
chr86818359968183682-intron-Distal3.661914.30679K562KHSRP
chr86809550068095664-intron-Distal4.643826.58366HepG2SUGP2
chr86825526468255344-intron-Distal,intron-Proximal4.308824.24431HepG2RBFOX2
chr86825525368255338-intron-Distal,intron-Proximal3.151533.40058K562PRPF8
chr86811563668115743-intron-Distal3.507184.13948HepG2PRPF4
chr86824024468240316-intron-Distal3.308123.26015K562PTBP1
chr86825526768255343-intron-Distal,intron-Proximal3.058514.67313HepG2PRPF4
chr86818030868180414-intron-Distal3.515645.32884K562KHSRP
chr86812683568126896-intron-Distal3.914773.54208HepG2SUGP2
chr86824411568244230-intron-Distal4.032543.92684K562KHSRP
chr86812351168123586-intron-Distal4.164734.02766HepG2HNRNPC
chr86824434668244444-intron-Distal4.313804.76003K562KHSRP
chr86825525168255342-intron-Distal,intron-Proximal3.373135.03137K562GTF2F1
chr86818378268183810-intron-Distal3.739363.06150K562KHSRP
chr86824428068244346-intron-Distal3.074323.76473K562KHSRP
chr86825512768255192-intron-Distal4.384433.85435K562PRPF8
chr86825527268255334-intron-Distal,intron-Proximal3.015884.84260HepG2EFTUD2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for ARFGEF1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for ARFGEF1 is not available on ENCORE database.

  • 60 RBPs can affect the levels of ARFGEF1.  








The Knockdown/knockout RNA-Seq assay for ARFGEF1 is not available on ENCORE database.





60 RBPs can affect the gene expression of ARFGEF1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
ARFGEF1ENSG00000066777.42517.473801928.512400.384402.629802.11070HepG2AKAP1
ARFGEF1ENSG00000066777.41281.065901595.67490-0.316802.063501.38130HepG2ASCC1
ARFGEF1ENSG00000066777.4649.922901184.36670-0.865808.143206.49010HepG2BCCIP
ARFGEF1ENSG00000066777.4939.737401128.64230-0.264302.250101.33420HepG2YBX3
ARFGEF1ENSG00000066777.41208.726101568.08860-0.375506.365305.30730HepG2DAZAP1
ARFGEF1ENSG00000066777.4594.35270882.30820-0.570004.085702.41010HepG2DDX28
ARFGEF1ENSG00000066777.41183.101501847.35360-0.642906.844705.90370HepG2DDX3X
ARFGEF1ENSG00000066777.41018.215401255.11350-0.301803.195702.47650HepG2DKC1
ARFGEF1ENSG00000066777.4884.746901098.44010-0.312103.867103.12240HepG2DNAJC2
ARFGEF1ENSG00000066777.41429.894701040.594700.458402.894601.76000HepG2AGO1
ARFGEF1ENSG00000066777.41095.166701525.53870-0.478204.047203.34000HepG2EIF2S1
ARFGEF1ENSG00000066777.41851.816401547.016200.259402.874002.02380HepG2EIF4G1
ARFGEF1ENSG00000066777.41814.217101481.942400.291802.097101.38110HepG2EIF4G2
ARFGEF1ENSG00000066777.4985.325801281.96640-0.379703.425502.49410HepG2EWSR1
ARFGEF1ENSG00000066777.41940.504601516.715400.355402.333101.62220HepG2FIP1L1
ARFGEF1ENSG00000066777.41389.458501701.03710-0.291901.874801.30110HepG2FXR1
ARFGEF1ENSG00000066777.41135.853001676.72160-0.561904.966604.12420HepG2GPKOW
ARFGEF1ENSG00000066777.4981.806101262.86150-0.363205.636204.62200HepG2ILF2
ARFGEF1ENSG00000066777.41057.301901701.63120-0.686507.568406.49820HepG2MAGOH
ARFGEF1ENSG00000066777.41190.294601711.14650-0.523604.304703.53440HepG2MATR3
ARFGEF1ENSG00000066777.41199.216601751.44660-0.546504.917304.08560HepG2NCBP2
ARFGEF1ENSG00000066777.41386.318101619.29450-0.224102.289801.72720HepG2PCBP1
ARFGEF1ENSG00000066777.41341.386001136.656800.238802.246301.54240HepG2PRPF4
ARFGEF1ENSG00000066777.41157.748001484.30110-0.358503.159402.52890HepG2PUF60
ARFGEF1ENSG00000066777.41076.430301336.22940-0.311903.907903.20030HepG2PUS1
ARFGEF1ENSG00000066777.42095.637401784.482000.231802.098401.54280HepG2QKI
ARFGEF1ENSG00000066777.42185.718701767.045900.306702.530801.70750HepG2RBM15
ARFGEF1ENSG00000066777.42013.109701619.539700.313702.905302.21670HepG2RBM25
ARFGEF1ENSG00000066777.41032.876001583.85660-0.616807.058205.97470HepG2SF3B1
ARFGEF1ENSG00000066777.41408.684402014.87220-0.5163010.795409.98230HepG2SRFBP1
ARFGEF1ENSG00000066777.42112.386101790.569100.238402.831202.35400HepG2SRSF1
ARFGEF1ENSG00000066777.41917.467401456.729300.396406.910006.10880HepG2SRSF9
ARFGEF1ENSG00000066777.41237.905901666.71270-0.429107.685406.73400HepG2SUCLG1
ARFGEF1ENSG00000066777.4728.250001061.73640-0.543902.625901.64980HepG2UPF2
ARFGEF1ENSG00000066777.41146.557401401.88460-0.290103.379302.72910HepG2UTP3
ARFGEF1ENSG00000066777.41786.707301271.049400.491202.965401.65740HepG2XRCC5
ARFGEF1ENSG00000066777.4681.137801141.15280-0.744507.060405.91400HepG2XRN2
ARFGEF1ENSG00000066777.41780.537202286.59710-0.360905.783505.01080K562AGGF1
ARFGEF1ENSG00000066777.41449.470802386.33760-0.7193010.770309.72560K562AQR
ARFGEF1ENSG00000066777.41047.921801305.21100-0.316803.263801.81380K562BCCIP
ARFGEF1ENSG00000066777.43235.490802383.047100.441109.175608.07270K562DDX47
ARFGEF1ENSG00000066777.41121.210101470.49990-0.391303.458402.54490K562EIF4A3
ARFGEF1ENSG00000066777.4981.839001283.61190-0.386704.133102.50670K562EWSR1
ARFGEF1ENSG00000066777.41140.059201670.66110-0.551306.399905.07240K562FIP1L1
ARFGEF1ENSG00000066777.42270.985401619.353200.487803.478902.66750K562G3BP2
ARFGEF1ENSG00000066777.41185.363101461.47200-0.302102.337301.60650K562GPKOW
ARFGEF1ENSG00000066777.41126.686102093.88630-0.8941017.4136015.47360K562GRSF1
ARFGEF1ENSG00000066777.41545.278002153.68000-0.478905.985204.37090K562HNRNPL
ARFGEF1ENSG00000066777.41823.733302265.17330-0.312702.413401.66670K562HSPD1
ARFGEF1ENSG00000066777.41345.688302060.91990-0.614909.122407.54170K562MAGOH
ARFGEF1ENSG00000066777.41693.149902056.79010-0.280702.462001.59550K562MATR3
ARFGEF1ENSG00000066777.42050.284502828.70830-0.464306.357304.87060K562MBNL1
ARFGEF1ENSG00000066777.41358.298801711.96800-0.333904.739803.70420K562MTPAP
ARFGEF1ENSG00000066777.41639.570101902.18450-0.214303.009102.23450K562NSUN2
ARFGEF1ENSG00000066777.41089.927701892.26960-0.795904.297502.99130K562PABPN1
ARFGEF1ENSG00000066777.41242.070001896.41620-0.610505.382604.17680K562PPIG
ARFGEF1ENSG00000066777.4765.753401058.44950-0.467002.401301.56530K562PSIP1
ARFGEF1ENSG00000066777.42893.556603357.13060-0.214402.188001.33250K562PUM2
ARFGEF1ENSG00000066777.41439.818501920.13880-0.415304.051503.01450K562RBM22
ARFGEF1ENSG00000066777.4690.55060965.32860-0.483302.403001.48320K562RCC2
ARFGEF1ENSG00000066777.4794.926001080.33570-0.442602.631301.83750K562RPS19
ARFGEF1ENSG00000066777.41466.810601986.63550-0.437604.100603.23390K562TARDBP
ARFGEF1ENSG00000066777.41507.222501916.31290-0.346403.504102.56610K562TIA1
ARFGEF1ENSG00000066777.4749.637501018.09620-0.441602.125801.31670K562TIAL1
ARFGEF1ENSG00000066777.42899.732803631.80030-0.324803.188301.67550K562UBE2L3
ARFGEF1ENSG00000066777.42074.196601794.624700.208802.498201.69200K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for ARFGEF1 is not available on ENCORE database.





3 RBPs can affect the splicing of ARFGEF1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEARFGEF1ENSG00000066777.4chr8-681288246812889768123717681238506813001668130155-0.122000.001320.01541excludedK562AQR
A3SSARFGEF1ENSG00000066777.4chr8-6812882468128933681288246812889768130016681301550.077000.000000.00000longerHepG2U2AF2
A3SSARFGEF1ENSG00000066777.4chr8-6811691468117106681169146811705468123717681238500.099000.004010.02382longerK562AQR
A3SSARFGEF1ENSG00000066777.4chr8-6811370168113859681137016811384068115317681155360.063000.015410.07650longerK562AQR
A3SSARFGEF1ENSG00000066777.4chr8-6811263068112767681126306811274868113701681138400.194000.002250.01432longerK562AQR
A3SSARFGEF1ENSG00000066777.4chr8-6813825768138443681382576813841868139371681395440.084000.000390.00302longerK562AQR
A3SSARFGEF1ENSG00000066777.4chr8-6812882468128925681288246812889768130016681301550.092000.002500.01570longerK562AQR
A3SSARFGEF1ENSG00000066777.4chr8-6812884268128933681288426812889768130016681301550.154000.000000.00000longerHepG2U2AF1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for ARFGEF1 is not avaliable on ENCORE database.