NCK2

General Information

Gene Name       : NCK2
Gene ID             : ENSG00000071051.13
Essential Gene : No

Functions

Localization

Domains (AlphaFold: NCK2)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878NCK2ENSG00000071051.136.3710.498.43ENCSR000AEF
HepG2NCK2ENSG00000071051.1336.3815.7626.07ENCSR985KAT
K562NCK2ENSG00000071051.1315.8510.6813.27ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for NCK2 is not avaliable on ENCORE database.



Proteins bound to RNA
  • NCK2 RNA is bound by 22 proteins.  







eCLIP assay for NCK2 is not avaliable on ENCORE database.





22 proteins are bound to NCK2 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr2106510124106510233+3'-UTR3.913213.47885K562LIN28B
chr2106510274106510318+3'-UTR3.252893.37083K562UPF1
chr2106432963106433067+3'-UTR,5'-UTR3.065135.18023HepG2GRWD1
chr2106471517106471656+3'-UTR,5'-UTR,CDS4.041149.74809K562ZNF622
chr2106510279106510331+3'-UTR3.327373.54602K562TIA1
chr2106471503106471696+3'-UTR,5'-UTR,CDS,intron-Proximal4.4124710.84390HepG2GRWD1
chr2106471503106471552+3'-UTR,5'-UTR,CDS,intron-Proximal3.476063.69481K562UCHL5
chr2106510492106510577+3'-UTR3.611528.61569K562HNRNPL
chr2106361509106361571+5'-UTR4.330878.30191HepG2DDX3X
chr2106361396106361476+5'-UTR3.061933.38092HepG2NKRF
chr2106361367106361498+5'-UTR5.8274335.77724HepG2DDX3X
chr2106361406106361481+5'-UTR3.314993.41847HepG2GTF2F1
chr2106361367106361487+5'-UTR3.458673.52645HepG2NCBP2
chr2106361368106361477+5'-UTR3.879356.25245HepG2PRPF4
chr2106497928106497988+CDS,intron-Distal3.941833.15006K562RBM15
chr2106471535106471755+CDS,intron-Proximal4.018933.58172HepG2SRSF1
chr2106471654106471741+CDS3.749283.02919K562GRWD1
chr2106498478106498556+CDS,intron-Distal,intron-Proximal4.911555.35117HepG2PRPF8
chr2106498241106498323+CDS,intron-Distal3.765723.06853K562LIN28B
chr2106361615106361706+intron-Distal,intron-Proximal3.670623.48123K562XRN2
chr2106424321106424410+intron-Distal4.118494.07628HepG2PTBP1
chr2106428509106428580+intron-Distal4.788774.17759HepG2QKI
chr2106452889106453048+intron-Distal4.629456.35761K562HNRNPM
chr2106507545106507665+intron-Distal3.254584.30735HepG2HNRNPL
chr2106374185106374271+intron-Distal3.452553.94088HepG2QKI
chr2106361851106361918+intron-Distal4.153714.48935K562CSTF2T
chr2106370466106370562+intron-Distal4.432283.97018HepG2HNRNPM
chr2106377643106377726+intron-Distal4.018404.10323HepG2PRPF4
chr2106362055106362116+intron-Distal4.406334.48935K562CSTF2T
chr2106384338106384430+intron-Distal5.205327.62903HepG2QKI
chr2106369340106369457+intron-Distal3.953943.37631K562HNRNPL
chr2106396783106396894+intron-Distal3.049756.91894K562AGGF1
chr2106424329106424436+intron-Distal5.5795211.78180HepG2PCBP2
chr2106396746106396895+intron-Distal3.935203.37631K562HNRNPL
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for NCK2 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for NCK2 is not available on ENCORE database.

  • 70 RBPs can affect the levels of NCK2.  








The Knockdown/knockout RNA-Seq assay for NCK2 is not available on ENCORE database.





70 RBPs can affect the gene expression of NCK2 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
NCK2ENSG00000071051.9146.02200302.15500-1.049107.697806.01650HepG2AATF
NCK2ENSG00000071051.9372.33940261.735800.508402.792701.79200HepG2ADAR
NCK2ENSG00000071051.9420.73040598.84450-0.509303.200402.08320HepG2AKAP8
NCK2ENSG00000071051.9795.22390660.251500.268202.135001.51820HepG2AUH
NCK2ENSG00000071051.9319.70430908.35780-1.5065027.7692026.20170HepG2BOP1
NCK2ENSG00000071051.9380.21830592.57200-0.640206.024504.94330HepG2CALR
NCK2ENSG00000071051.9427.94520548.58770-0.358302.919102.24040HepG2CKAP4
NCK2ENSG00000071051.9295.33530426.31790-0.529602.139201.47350HepG2CNOT7
NCK2ENSG00000071051.9599.78300466.569800.362202.681602.04670HepG2CELF1
NCK2ENSG00000071051.9176.32970262.74850-0.575402.792701.39430HepG2DDX28
NCK2ENSG00000071051.9338.61550261.225700.374302.295701.68960HepG2DNAJC2
NCK2ENSG00000071051.9883.62920577.105000.614503.790602.99120HepG2EIF4B
NCK2ENSG00000071051.91029.38500758.077500.441305.388504.59750HepG2ETF1
NCK2ENSG00000071051.9713.09140536.190300.411203.087802.20820HepG2EWSR1
NCK2ENSG00000071051.9351.15340574.67840-0.710706.519605.34080HepG2FUBP3
NCK2ENSG00000071051.9364.67190554.70370-0.605103.554302.80430HepG2G3BP1
NCK2ENSG00000071051.9466.57230303.142100.622004.029602.93640HepG2GEMIN5
NCK2ENSG00000071051.9420.35520523.87990-0.317602.263101.37390HepG2HDGF
NCK2ENSG00000071051.9415.77620266.081900.643804.289003.50860HepG2HNRNPA1
NCK2ENSG00000071051.9614.22430902.18410-0.554704.486303.70310HepG2HNRNPLL
NCK2ENSG00000071051.9415.50150300.320600.468303.931103.07240HepG2ILF2
NCK2ENSG00000071051.91772.01960995.132500.832308.351006.90320HepG2LARP4
NCK2ENSG00000071051.9589.75200920.02000-0.641603.896602.73360HepG2MTPAP
NCK2ENSG00000071051.9515.41980318.621100.693802.821001.71780HepG2NONO
NCK2ENSG00000071051.9635.69820799.92870-0.331501.949501.31640HepG2NSUN2
NCK2ENSG00000071051.9162.15730291.02010-0.843706.595605.37220HepG2PARN
NCK2ENSG00000071051.9529.97070262.232701.0150014.0878012.49620HepG2PPIL4
NCK2ENSG00000071051.9361.07350481.22420-0.414402.954602.15810HepG2PRPF4
NCK2ENSG00000071051.9279.40340420.24980-0.588902.706501.50000HepG2PRPF6
NCK2ENSG00000071051.9599.26450474.889800.335501.905201.39740HepG2PUF60
NCK2ENSG00000071051.9669.53940504.106500.409304.288103.58360HepG2PUM1
NCK2ENSG00000071051.9711.67830503.744500.498402.089401.50160HepG2PUM2
NCK2ENSG00000071051.9372.31420637.40940-0.775708.733807.71910HepG2QKI
NCK2ENSG00000071051.9568.46250385.703200.559502.286801.64220HepG2RAVER1
NCK2ENSG00000071051.9656.95470821.29740-0.322102.345101.54850HepG2RBM15
NCK2ENSG00000071051.9437.84640633.60820-0.533204.864104.22540HepG2RBM22
NCK2ENSG00000071051.9764.73150331.359001.2065018.7487017.35930HepG2RPS19
NCK2ENSG00000071051.9565.82460350.887700.689203.996203.04330HepG2RPS2
NCK2ENSG00000071051.9585.15380428.063900.450902.179201.46890HepG2RPS3A
NCK2ENSG00000071051.9379.25340261.828700.534404.081603.32540HepG2SAFB2
NCK2ENSG00000071051.9967.06620753.141200.360601.923301.35860HepG2SF3A3
NCK2ENSG00000071051.9519.49650305.337800.766609.769608.67790HepG2SMN1
NCK2ENSG00000071051.9569.08780993.61940-0.804005.611704.48810HepG2SNRNP70
NCK2ENSG00000071051.9979.80790715.629600.453205.779305.12860HepG2SRFBP1
NCK2ENSG00000071051.9477.32870639.60450-0.422203.554003.03450HepG2SRSF1
NCK2ENSG00000071051.9368.01860520.36760-0.499804.516703.84370HepG2SRSF9
NCK2ENSG00000071051.9363.19710536.96950-0.564102.913601.64810HepG2STAU1
NCK2ENSG00000071051.9695.41890533.247500.383003.482202.79940HepG2SUCLG1
NCK2ENSG00000071051.9220.01050574.95060-1.3859022.6635021.27790HepG2TAF15
NCK2ENSG00000071051.9341.76320231.443200.562202.801101.80030HepG2TFIP11
NCK2ENSG00000071051.9416.12300528.24920-0.344202.087501.35880HepG2TIA1
NCK2ENSG00000071051.9376.25480285.689500.397202.163001.70960HepG2TIAL1
NCK2ENSG00000071051.9423.15440288.238100.553802.903002.32870HepG2TRIM56
NCK2ENSG00000071051.9639.26620463.931000.462403.399202.42040HepG2TUFM
NCK2ENSG00000071051.9418.83950687.73970-0.715506.100305.18360HepG2U2AF1
NCK2ENSG00000071051.9688.59960473.578500.540005.946505.16420K562AGGF1
NCK2ENSG00000071051.9666.40030517.053100.366003.020102.06680K562ATP5C1
NCK2ENSG00000071051.9272.98220178.124400.615803.326702.14840K562CCAR1
NCK2ENSG00000071051.9742.57080555.637400.418303.028001.49030K562DDX19B
NCK2ENSG00000071051.9486.09740321.275200.597302.658501.63680K562DDX3X
NCK2ENSG00000071051.9742.57080592.162000.326402.708802.06340K562DDX47
NCK2ENSG00000071051.9726.10690530.251600.453404.497603.34300K562DKC1
NCK2ENSG00000071051.9533.33460286.541200.8962011.061409.76810K562EIF2S2
NCK2ENSG00000071051.9305.87580181.177400.755403.006201.95190K562EIF3A
NCK2ENSG00000071051.9527.72590381.814700.466802.936102.15890K562GRSF1
NCK2ENSG00000071051.9774.25550508.648600.606005.348304.25920K562HSPD1
NCK2ENSG00000071051.9785.52570585.843800.423003.520502.47730K562MBNL1
NCK2ENSG00000071051.9326.56110186.318000.809504.337403.30970K562RPS19
NCK2ENSG00000071051.9216.38180155.657600.475102.118701.37190K562SF3B4
NCK2ENSG00000071051.9338.53790236.433700.517802.501001.72830K562TIA1
NCK2ENSG00000071051.9638.99090523.459200.287602.121501.48570K562UPF1
NCK2ENSG00000071051.9286.64690457.97290-0.676004.393202.87170K562UTP3
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for NCK2 is not available on ENCORE database.





3 RBPs can affect the splicing of NCK2 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SENCK2ENSG00000071051.9chr2+1064977831064985051064715031064717451065094371065107280.298000.000440.04460includedHepG2PRPF8
SENCK2ENSG00000071051.9chr2+1064977831064985051064715031064717451065094371065107280.272000.000010.00036includedHepG2U2AF2
SENCK2ENSG00000071051.9chr2+1064977831064985051064715031064717451065094371065107280.381000.000040.02196includedHepG2XPO5

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for NCK2 is not avaliable on ENCORE database.