DDX19B

General Information

Gene Name : DDX19B
Gene ID : ENSG00000157349.16
Essential Gene : No

Functions

RNA export

Localization(RBPImage: DDX19B)

Nuclei
Nucleoplasm
Mutually Exclusive from Nucleolus
Speckles
Cytoplasm
Cytosolic
Mitotic-Apparatus (Spindle; Centrosomes)

Domains (AlphaFold: DDX19B)

Helicase

Antibody Validation

View validation images for all DDX19B antibodies

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	DDX19B	ENSG00000157349.16	51.63	47.02	49.33	ENCSR000AEF
HepG2	DDX19B	ENSG00000157349.16	34.94	40.90	37.92	ENCSR985KAT
K562	DDX19B	ENSG00000157349.16	28.84	22.13	25.48	ENCSR000AEO

Assays

2 Released experiments are available on ENCORE database.

Assay Type	Exp_Name	ENCODE ID	Target label	Biosample	Status	Linked Antibody	Controls	Method	Note
knockdown followed by RNA-seq	DDX19B-BGKLV32-K562	ENCSR281IUF	DDX19B	K562	Released		ENCSR143COQ	shRNA	KD% = 94.5,92.2
knockdown followed by RNA-seq	DDX19B-BGHLV31-HepG2	ENCSR312SFA	DDX19B	HepG2	Released		ENCSR538QOG	shRNA	KD% = 83.9,85.2

eCLIP

No eCLIP experiment available

Antibody Validation

GeneName	Antibody_DCC_ID	Product_ID	Lot_ID	HepG2 Primary Validation	K562 Primary Validation	HepG2 Secondary Validation	K562 Secondary Validation
DDX19B	ENCAB890IXX	A300-545A	1	Released, ENCODE3	Released, ENCODE3	BGHLV31-25, Released, ENCODE3	BGKLV32-17, Released, ENCODE3
DDX19B	ENCAB726VLQ	A300-546A	1	Released, ENCODE3	Released, ENCODE4	BGHLV31-25, Released, ENCODE3	BGKLV32-17, Released, ENCODE4
DDX19B	ENCAB426ZIS	A300-547A	1	Released, ENCODE3	Released, ENCODE4	BGHLV31-25, Released, ENCODE3

KD RNA-Seq

GeneName	Cell_Line	Method	Exp_ID	Control_ID	Sample_reps	Control_reps	KD%	Status	Project	Note
DDX19B	K562	shRNA	ENCSR281IUF	ENCSR143COQ	DDX19B_BGKLV32-17,DDX19B_BGKLV32-18	NT_BGKLV32-1,NT_BGKLV32-2	94.5,92.2	Released	ENCODE3
DDX19B	HepG2	shRNA	ENCSR312SFA	ENCSR538QOG	DDX19B_BGHLV31-25,DDX19B_BGHLV31-26	NT-BGHLV31-1,NT-BGHLV31-2	83.9,85.2	Released	ENCODE3

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

DDX19B: Click to RBP Image Database

Nuclei

Nucleoplasm

Mutually Exclusive from Nucleolus

Speckles

Cytoplasm

Cytosolic

Mitotic-Apparatus (Spindle; Centrosomes)

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela
DDX19B	Product_ID: A300-545A Lot_ID: 1 Source: Bethyl Labs Target Name: DDX19B-human
DDX19B	Product_ID: A300-546A Lot_ID: 1 Source: Bethyl Labs Target Name: DDX19B-human
DDX19B	Product_ID: A300-547A Lot_ID: 1 Source: Bethyl Labs Target Name: DDX19B-human

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for DDX19B is not avaliable on ENCORE database.

Proteins bound to RNA

DDX19B RNA is bound by 6 proteins.

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eCLIP assay for DDX19B is not avaliable on ENCORE database.

6 proteins are bound to DDX19B RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr16	70335018	70335136	+	intron-Distal	5.63577	10.55181	HepG2	PTBP1
chr16	70335002	70335144	+	intron-Distal	4.34224	6.98272	HepG2	MATR3
chr16	70363963	70364022	+	3'-UTR,CDS,intron-Distal,intron-Proximal	4.84467	6.26248	HepG2	PRPF8
chr16	70333094	70333165	+	5'-UTR,intron-Distal	4.27962	4.78731	HepG2	NCBP2
chr16	70363776	70363869	+	3'-UTR,CDS,intron-Distal	4.05408	4.04622	HepG2	GRWD1
chr16	70367466	70367601	+	3'-UTR,CDS,intron-Distal	3.48030	3.80299	HepG2	GRWD1
chr16	70338924	70339005	+	intron-Distal	3.76106	3.04224	HepG2	SUGP2
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 7 of 7 entries

eCLIP assay for DDX19B is not avaliable on ENCORE database.

Diffrential Expression

5,295 differentially expressed genes after Knockdown/Knockout DDX19B protein.

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55 RBPs can affect the levels of DDX19B.

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5,295 differentially expressed genes after Knockdown/Knockout DDX19B protein :

Only display 100 entries as example. Please click "View All" button to see all 5,295 entries.

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
SLC7A2	ENSG00000003989.12	2803.66610	6772.05490	-1.27230	100.76030	97.69170	HepG2	DDX19B
CRLF1	ENSG00000006016.6	2146.88660	4609.29280	-1.10230	68.87440	66.23720	HepG2	DDX19B
CYP51A1	ENSG00000001630.11	2405.95520	5067.90210	-1.07480	68.05890	65.43750	HepG2	DDX19B
JHDM1D	ENSG00000006459.6	954.55260	2234.27970	-1.22690	61.00660	58.44990	HepG2	DDX19B
ZFX	ENSG00000005889.11	1978.08100	933.42450	1.08340	45.93300	43.63160	HepG2	DDX19B
PLXND1	ENSG00000004399.8	1429.34470	2645.71040	-0.88830	37.28940	35.12660	HepG2	DDX19B
TMEM98	ENSG00000006042.7	743.79450	1498.77830	-1.01080	34.86670	32.76190	HepG2	DDX19B
MAP4K3	ENSG00000011566.10	1611.44140	2879.75580	-0.83760	34.77490	32.67950	HepG2	DDX19B
LAMP2	ENSG00000005893.11	2212.04530	3570.40710	-0.69070	26.81540	24.88980	HepG2	DDX19B
SEMA3G	ENSG00000010319.2	362.62890	782.40940	-1.10940	26.32710	24.41240	HepG2	DDX19B
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 100 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

55 RBPs can affect the gene expression of DDX19B :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
DDX19B	ENSG00000157349.11	124.86360	913.23140	-2.87060	77.34310	73.24310	K562	DDX19B
DDX19B	ENSG00000157349.11	237.01460	767.83770	-1.69580	21.88700	20.07730	HepG2	DDX19B
DDX19B	ENSG00000157349.11	260.46720	591.78780	-1.18400	19.72680	17.86040	K562	MTPAP
DDX19B	ENSG00000157349.11	703.76880	301.86940	1.22110	13.74050	11.89640	K562	RPS19
DDX19B	ENSG00000157349.11	1096.99550	685.28150	0.67870	12.00290	10.74800	K562	DDX47
DDX19B	ENSG00000157349.11	1733.10360	1041.40250	0.73470	11.20210	9.98820	HepG2	RPLP0
DDX19B	ENSG00000157349.11	394.66270	657.48420	-0.73630	10.87500	9.52840	K562	NSUN2
DDX19B	ENSG00000157349.11	1624.96650	1140.24170	0.51100	9.19820	7.84230	HepG2	EIF4G1
DDX19B	ENSG00000157349.11	413.66020	648.83630	-0.64940	6.54240	5.33440	K562	SF3A3
DDX19B	ENSG00000157349.11	497.88720	313.96280	0.66510	6.22400	5.04870	K562	EIF3G
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 62 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

DDX19B

General Information

Functions

Localization(RBPImage: DDX19B)

Domains (AlphaFold: DDX19B)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for DDX19B is not avaliable on ENCORE database.

6 proteins are bound to DDX19B RNA:

eCLIP assay for DDX19B is not avaliable on ENCORE database.

Diffrential Expression

5,295 differentially expressed genes after Knockdown/Knockout DDX19B protein :

55 RBPs can affect the gene expression of DDX19B :

The Knockdown/knockout RNA-Seq assay for DDX19B is not available on ENCORE database.

No RBPs affect the alternative splcing events of DDX19B on ENCORE database.

The Knockdown/knockout RNA-Seq assay for DDX19B is not avaliable on ENCORE database.