FYN

General Information

Gene Name       : FYN
Gene ID             : ENSG00000010810.17
Essential Gene : No

Functions

Localization

Domains (AlphaFold: FYN)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878FYNENSG00000010810.1796.10130.56113.33ENCSR000AEF
HepG2FYNENSG00000010810.1748.8845.7547.31ENCSR985KAT
K562FYNENSG00000010810.1711.7414.8913.32ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for FYN is not avaliable on ENCORE database.



Proteins bound to RNA
  • FYN RNA is bound by 4 proteins.  







eCLIP assay for FYN is not avaliable on ENCORE database.





4 proteins are bound to FYN RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr6112015619112015732-CDS,intron-Distal,intron-Proximal4.030345.65086HepG2BCLAF1
chr6112015829112015898-CDS,intron-Distal,intron-Proximal4.300623.02457HepG2BCLAF1
chr6112094613112094690-intron-Distal5.123253.77881HepG2PCBP2
chr6112094452112094563-intron-Distal4.701695.11777HepG2DDX59
chr6112151884112151976-intron-Distal4.245034.30850HepG2QKI
chr6112094478112094575-intron-Distal5.738929.00303HepG2PCBP2
chr6112024009112024075-intron-Distal,intron-Proximal4.218803.55640HepG2QKI
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for FYN is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for FYN is not available on ENCORE database.

  • 112 RBPs can affect the levels of FYN.  








The Knockdown/knockout RNA-Seq assay for FYN is not available on ENCORE database.





112 RBPs can affect the gene expression of FYN :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
FYNENSG00000010810.13995.93250660.538300.592306.071504.54680HepG2AATF
FYNENSG00000010810.13397.70050689.84480-0.794606.832105.43120HepG2ABCF1
FYNENSG00000010810.13945.04370477.928000.9835014.6567013.49130HepG2ACO1
FYNENSG00000010810.13578.68960911.12310-0.654906.411104.96920HepG2ADAR
FYNENSG00000010810.131328.51600904.240100.554904.220803.58260HepG2AKAP1
FYNENSG00000010810.13807.92450498.393200.696805.827504.34460HepG2AKAP8
FYNENSG00000010810.13366.50760480.19140-0.389802.819402.04630HepG2AKAP8L
FYNENSG00000010810.131218.89470944.890700.367304.306803.48420HepG2AUH
FYNENSG00000010810.13569.48220801.65290-0.493302.819401.91310HepG2BCLAF1
FYNENSG00000010810.13438.03950944.43540-1.1084016.8745015.57770HepG2BOP1
FYNENSG00000010810.13590.18140477.845700.304502.351001.72990HepG2CKAP4
FYNENSG00000010810.13452.94460867.05980-0.9368011.211409.93090HepG2CPSF6
FYNENSG00000010810.13736.04460568.211900.373302.700201.60800HepG2CPSF7
FYNENSG00000010810.13416.79790569.93400-0.451402.515801.48690HepG2CSTF2
FYNENSG00000010810.131901.053701173.510700.6959015.5210014.24300HepG2CELF1
FYNENSG00000010810.13638.07480442.024800.529505.063803.98160HepG2DDX19B
FYNENSG00000010810.13503.66890728.59430-0.532604.464503.62430HepG2DDX21
FYNENSG00000010810.13653.99300866.17780-0.405402.481001.88570HepG2DDX3X
FYNENSG00000010810.131610.54530906.952100.828409.835408.48320HepG2DDX55
FYNENSG00000010810.13323.03560610.20580-0.917609.542407.80450HepG2DDX5
FYNENSG00000010810.131171.31810744.101800.654505.618404.76540HepG2DDX6
FYNENSG00000010810.13522.19060884.87970-0.760909.123507.44690HepG2DHX30
FYNENSG00000010810.13258.21510457.25320-0.824408.793907.72170HepG2DKC1
FYNENSG00000010810.13714.63410917.44110-0.360403.409702.63430HepG2DNAJC21
FYNENSG00000010810.13631.26060849.88230-0.429002.897101.95560HepG2EEF2
FYNENSG00000010810.13673.22880523.387700.363102.537201.42140HepG2EIF2S2
FYNENSG00000010810.13939.54410689.864200.445503.320202.33560HepG2EIF3D
FYNENSG00000010810.13466.56010688.13910-0.560605.227303.79820HepG2EIF3G
FYNENSG00000010810.13314.53360790.45760-1.3295016.9141015.34310HepG2EIF4A3
FYNENSG00000010810.131537.25000769.655400.9980010.284909.00210HepG2EIF4B
FYNENSG00000010810.13933.389001244.86850-0.415404.619203.57920HepG2EIF4G1
FYNENSG00000010810.13457.260501192.52080-1.3829027.2189024.93370HepG2EIF4G2
FYNENSG00000010810.131294.96130696.600000.894409.865308.53030HepG2FIP1L1
FYNENSG00000010810.13301.50300868.51130-1.526409.633007.76820HepG2FTO
FYNENSG00000010810.131329.54640886.242600.585103.932002.60730HepG2FUS
FYNENSG00000010810.131017.11430797.592500.350702.150701.53700HepG2FXR1
FYNENSG00000010810.13543.30830785.48870-0.531803.975202.89890HepG2G3BP2
FYNENSG00000010810.13360.50500982.92540-1.4471021.7290020.12010HepG2GPKOW
FYNENSG00000010810.13568.08240926.23080-0.705307.812706.81010HepG2HNRNPA1
FYNENSG00000010810.13680.971101030.27250-0.597406.040005.04410HepG2HNRNPC
FYNENSG00000010810.13517.542101024.43550-0.9851021.6073019.86820HepG2HNRNPF
FYNENSG00000010810.131011.13420749.237100.432403.280902.52170HepG2HNRNPK
FYNENSG00000010810.13372.43220938.01970-1.3326020.4329018.96900HepG2HNRNPLL
FYNENSG00000010810.13746.21830480.686100.634406.617505.23260HepG2HNRNPM
FYNENSG00000010810.131255.462001023.460000.294703.251902.59820HepG2HNRNPU
FYNENSG00000010810.13443.677201008.77970-1.1850023.6912021.82180HepG2IGF2BP1
FYNENSG00000010810.131074.77580705.794900.606602.174801.31160HepG2IGF2BP3
FYNENSG00000010810.131058.41490756.439600.484502.978201.93210HepG2KHSRP
FYNENSG00000010810.131203.851701625.29070-0.433002.789401.95570HepG2LARP4
FYNENSG00000010810.131078.53030796.000300.438103.541702.25670HepG2LARP7
FYNENSG00000010810.13420.32540797.87120-0.924609.835408.61890HepG2MAGOH
FYNENSG00000010810.131494.64600721.969201.049709.664407.82770HepG2METAP2
FYNENSG00000010810.13765.13170563.880900.440203.603602.68190HepG2MSI2
FYNENSG00000010810.13470.99250956.55850-1.022108.630506.89410HepG2MTPAP
FYNENSG00000010810.13641.46800821.22020-0.356401.977301.43690HepG2NCBP2
FYNENSG00000010810.13516.06860719.72680-0.479903.809502.12990HepG2NIP7
FYNENSG00000010810.13333.54180831.70070-1.3182019.0643017.32670HepG2NSUN2
FYNENSG00000010810.13455.40610671.23190-0.559702.565301.71790HepG2PABPC1
FYNENSG00000010810.131269.634701013.035300.325603.687402.72450HepG2PARN
FYNENSG00000010810.131324.45380801.505800.7245015.0476013.81480HepG2PCBP1
FYNENSG00000010810.13707.53900912.84250-0.367603.513102.69230HepG2PPIL4
FYNENSG00000010810.13468.25790742.14540-0.664407.362206.17260HepG2PRPF4
FYNENSG00000010810.131117.25320815.530200.454005.848505.11270HepG2PTBP1
FYNENSG00000010810.13829.969701194.45570-0.525205.736004.91900HepG2PUF60
FYNENSG00000010810.131030.943201267.02810-0.297502.635201.98020HepG2PUM2
FYNENSG00000010810.13732.07030486.803800.588507.892106.94070HepG2PUS1
FYNENSG00000010810.131295.68870809.549400.678403.866603.03700HepG2RAVER1
FYNENSG00000010810.131182.37580670.579400.8181013.5248011.84430HepG2RBM15
FYNENSG00000010810.131450.05390906.741400.677207.239906.49340HepG2RBM22
FYNENSG00000010810.13521.06230779.45070-0.581004.016902.73810HepG2RCC2
FYNENSG00000010810.13654.04040845.28890-0.370103.646002.95130HepG2RECQL
FYNENSG00000010810.13704.769701103.51900-0.646907.325506.29300HepG2RPLP0
FYNENSG00000010810.13375.21570795.31370-1.083809.339807.70860HepG2RPS10
FYNENSG00000010810.13823.76160671.320500.295101.850501.33810HepG2RPS19
FYNENSG00000010810.13506.28640737.28050-0.542303.180602.32400HepG2RPS3A
FYNENSG00000010810.13668.45670928.48050-0.474003.801002.98510HepG2SF3B1
FYNENSG00000010810.13739.879801145.22550-0.6303012.5157011.20880HepG2SLBP
FYNENSG00000010810.13316.223101033.08800-1.7079020.9246018.85160HepG2SNRNP70
FYNENSG00000010810.132610.826301024.132001.3500071.0426069.38720HepG2SRFBP1
FYNENSG00000010810.131075.99900886.284000.279702.487402.03280HepG2SRSF1
FYNENSG00000010810.13951.176401179.30940-0.310203.439202.75470HepG2SRSF5
FYNENSG00000010810.13695.393701006.46270-0.533407.459106.40530HepG2SRSF7
FYNENSG00000010810.13874.71410721.019100.278702.444301.91860HepG2SRSF9
FYNENSG00000010810.13308.32230889.19060-1.5281042.4445041.01430HepG2SSB
FYNENSG00000010810.13484.21920902.92590-0.898908.079307.02070HepG2SUPV3L1
FYNENSG00000010810.13964.32080796.561600.275602.138901.63420HepG2TAF15
FYNENSG00000010810.13538.82020914.15780-0.762608.446407.27410HepG2TARDBP
FYNENSG00000010810.13365.67480994.43790-1.4433033.8551032.46090HepG2TIAL1
FYNENSG00000010810.13871.149201166.87590-0.421704.089303.00430HepG2TUFM
FYNENSG00000010810.131135.65510595.952100.9302012.5373011.16760HepG2U2AF1
FYNENSG00000010810.131204.33510675.830800.833402.280801.39660HepG2U2AF2
FYNENSG00000010810.13736.49710533.433300.465303.565302.70690HepG2UCHL5
FYNENSG00000010810.13384.89690826.98550-1.103409.077707.22130HepG2UPF2
FYNENSG00000010810.13624.53980477.920400.385903.179502.06480HepG2UTP18
FYNENSG00000010810.13863.98810448.908900.9445018.4979017.15930HepG2UTP3
FYNENSG00000010810.13449.38460660.37030-0.555303.186101.99990HepG2XPO5
FYNENSG00000010810.13475.61080888.82940-0.902108.381107.13350HepG2XRN2
FYNENSG00000010810.13565.43700732.44090-0.373303.642602.88940HepG2ZC3H8
FYNENSG00000010810.13262.74730511.37660-0.9607014.4228013.41640HepG2ZNF622
FYNENSG00000010810.13565.44280808.89610-0.516603.066301.69520HepG2ZRANB2
FYNENSG00000010810.13288.10630555.78100-0.9479012.4100011.30200K562AGGF1
FYNENSG00000010810.13331.70250578.30680-0.801907.944906.78360K562AKAP8L
FYNENSG00000010810.13383.88580606.76700-0.660507.271205.69030K562ATP5C1
FYNENSG00000010810.13192.34090303.99930-0.660403.429102.45920K562BOP1
FYNENSG00000010810.13586.30290377.412600.635403.055001.93020K562CNOT7
FYNENSG00000010810.13915.06710597.319900.615306.091004.65090K562CELF1
FYNENSG00000010810.13507.59000622.35280-0.294102.044301.30290K562DKC1
FYNENSG00000010810.13442.56500340.849600.376702.444801.76170K562EIF2S2
FYNENSG00000010810.13184.46500278.74910-0.595602.939001.99520K562FTO
FYNENSG00000010810.13333.13090244.212700.447902.183101.64440K562HNRNPC
FYNENSG00000010810.13450.97900309.388400.543504.342403.21220K562HNRNPU
FYNENSG00000010810.13745.09140451.748900.721807.029705.77260K562HSPD1
FYNENSG00000010810.13420.71120613.75780-0.544804.206003.16080K562KIF1C
FYNENSG00000010810.13414.41540263.512500.653103.361802.32210K562KRR1
FYNENSG00000010810.13418.50850236.466800.823506.939004.60450K562LARP7
FYNENSG00000010810.13323.62050241.036200.425002.201001.38710K562MATR3
FYNENSG00000010810.13471.23880687.55960-0.545004.805603.54350K562MBNL1
FYNENSG00000010810.13332.53830481.92690-0.535302.645701.78660K562NAA15
FYNENSG00000010810.13468.15550359.864200.379402.811802.05940K562NSUN2
FYNENSG00000010810.13615.85320412.916800.576603.868602.88530K562PCBP3
FYNENSG00000010810.13449.71530316.717300.505703.364902.47470K562POLR2G
FYNENSG00000010810.13814.11370529.853300.619505.022403.92440K562PUF60
FYNENSG00000010810.13193.60300573.58250-1.5669021.6308020.13840K562PUS1
FYNENSG00000010810.13316.86000558.81930-0.818507.040606.12330K562RBM15
FYNENSG00000010810.13495.01590363.811900.444203.599102.54760K562SRPK2
FYNENSG00000010810.13335.78210214.803300.644403.830002.61350K562UCHL5
FYNENSG00000010810.13529.68860410.792300.366602.106301.36350K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for FYN is not available on ENCORE database.





22 RBPs can affect the splicing of FYN :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEFYNENSG00000010810.13chr6-112062183112062296112041007112041265112101768112101838-0.118000.000010.00138excludedHepG2RBM22
SEFYNENSG00000010810.13chr6-1120621831120622961120410071120412651121017681121018380.069000.002220.09431includedHepG2PTBP1
SEFYNENSG00000010810.13chr6-1120621831120622961120410071120412651121017681121018380.071000.003440.06638includedHepG2SRSF1
SEFYNENSG00000010810.13chr6-1120621831120622961120410071120412651121017681121018380.090000.000190.01972includedHepG2IGF2BP3
SEFYNENSG00000010810.13chr6-112020717112020873112017479112017659112024087112024237-0.206000.004250.09864excludedK562UTP18
MXEFYNENSG00000010810.13chr6-1120207171120208731120213061120214711120174791120176591120240871120242370.149000.004140.062991includedHepG2U2AF1
MXEFYNENSG00000010810.13chr6-1120207171120208731120213061120214711120174791120176591120240871120242370.433000.000260.011901includedK562UCHL5
MXEFYNENSG00000010810.13chr6-112020717112020908112021306112021471112017479112017659112024087112024237-0.199000.000000.000052includedHepG2SRSF1
MXEFYNENSG00000010810.13chr6-112020717112020873112021306112021471112017479112017659112024087112024237-0.275000.000000.000002includedHepG2SRSF1
MXEFYNENSG00000010810.13chr6-1120207171120208731120213061120214711120174791120176591120240871120242370.416000.000190.009811includedK562XRN2
MXEFYNENSG00000010810.13chr6-112020717112020873112021306112021471112017479112017659112024087112024237-0.373000.000020.000652includedK562SRSF1
MXEFYNENSG00000010810.13chr6-112020717112020873112021306112021471112017479112017659112024087112024237-0.205000.000000.000202includedHepG2SRSF9
MXEFYNENSG00000010810.13chr6-1120207171120208731120213061120214711120174791120176591120240871120242370.457000.000000.000011includedK562AQR
MXEFYNENSG00000010810.13chr6-1120207171120208731120213061120214711120174791120176591120240871120242370.344000.002500.032911includedK562U2AF2
MXEFYNENSG00000010810.13chr6-1120207171120208731120213061120214711120174791120176591120240871120242370.160000.000050.005231includedHepG2BCCIP
MXEFYNENSG00000010810.13chr6-1120207171120208731120213061120214711120174791120176591120240871120242370.209000.000000.000001includedHepG2U2AF2
MXEFYNENSG00000010810.13chr6-1120207171120208731120213061120214711120174791120176591120240871120242370.209000.000140.037911includedHepG2DHX30
MXEFYNENSG00000010810.13chr6-112020717112020873112021306112021471112017479112017659112024087112024237-0.287000.000540.067482includedK562PCBP1
MXEFYNENSG00000010810.13chr6-112020717112020873112021306112021471112017479112017659112024087112024237-0.166000.000010.000752includedHepG2PCBP1
MXEFYNENSG00000010810.13chr6-1120207171120208731120213061120214711120174791120176591120240871120242370.382000.000000.002071includedK562ZC3H8
MXEFYNENSG00000010810.13chr6-1120207171120208731120213061120214711120174791120176591120240871120242370.114000.000150.006041includedHepG2HNRNPK
MXEFYNENSG00000010810.13chr6-1120207171120208731120213061120214711120174791120176591120240871120242370.165000.000000.000541includedHepG2HNRNPL
MXEFYNENSG00000010810.13chr6-112020717112020873112021306112021471112017479112017659112024087112024237-0.318000.000000.000002includedHepG2DDX6
MXEFYNENSG00000010810.13chr6-1120207171120208731120213061120214711120174791120176591120240871120242370.168000.000120.019041includedHepG2PRPF8
MXEFYNENSG00000010810.13chr6-1120207171120208731120213061120214711120174791120176591120240871120242370.323000.003220.059131includedK562SUPV3L1
MXEFYNENSG00000010810.13chr6-1120207171120208731120213061120214711120174791120176591120240871120242370.253000.006460.073591includedK562HNRNPUL1
MXEFYNENSG00000010810.13chr6-1120207171120208731120213061120214711120174791120176591120240871120242370.426000.000440.039171includedK562SERBP1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for FYN is not avaliable on ENCORE database.