HEATR5B

General Information

Gene Name       : HEATR5B
Gene ID             : ENSG00000008869.11
Essential Gene : No

Functions

Localization

Domains (AlphaFold: HEATR5B)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878HEATR5BENSG00000008869.1113.6612.7313.20ENCSR000AEF
HepG2HEATR5BENSG00000008869.116.599.027.80ENCSR985KAT
K562HEATR5BENSG00000008869.117.407.277.33ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for HEATR5B is not avaliable on ENCORE database.



Proteins bound to RNA
  • HEATR5B RNA is bound by 7 proteins.  







eCLIP assay for HEATR5B is not avaliable on ENCORE database.





7 proteins are bound to HEATR5B RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr23720817037208225-3'-UTR,intron-Distal6.5905311.75835K562PUM2
chr23720849137208531-3'-UTR,intron-Distal4.816315.76540K562PUM2
chr23730262537302753-CDS,intron-Distal,intron-Proximal3.161206.61676HepG2PPIG
chr23729208837292120-CDS,intron-Distal3.039113.45280HepG2BCLAF1
chr23729601137296066-CDS,intron-Distal3.895366.81385HepG2BCLAF1
chr23728072137280747-CDS,intron-Distal4.461593.89826HepG2BCLAF1
chr23729596137296011-CDS,intron-Distal3.349926.60490HepG2BCLAF1
chr23726747037267513-CDS,intron-Distal,intron-Proximal3.635435.15500HepG2BCLAF1
chr23730262637302730-CDS,intron-Distal,intron-Proximal3.523384.65365HepG2GRWD1
chr23729198737292008-CDS,intron-Distal3.567343.27569HepG2BCLAF1
chr23729737137297409-CDS,intron-Distal,intron-Proximal4.217414.16554HepG2PPIG
chr23725514337255232-CDS,intron-Distal5.8262612.09921HepG2BCLAF1
chr23728603037286071-CDS,intron-Distal,intron-Proximal3.498594.74886HepG2BCLAF1
chr23729941237299424-CDS,intron-Distal3.776504.93978HepG2BCLAF1
chr23729290737292995-CDS,intron-Distal4.308413.79199HepG2PPIG
chr23728772137287769-CDS,intron-Distal,intron-Proximal3.384413.64266HepG2PPIG
chr23725582737255851-CDS,intron-Distal4.319363.71570HepG2BCLAF1
chr23730409937304129-CDS,intron-Distal3.580343.87469HepG2BCLAF1
chr23728785037287867-CDS,intron-Distal3.491343.68471HepG2BCLAF1
chr23728610237286184-CDS,intron-Distal,intron-Proximal5.009705.90023K562SF3B4
chr23728608537286143-CDS,intron-Distal,intron-Proximal3.701343.62357HepG2U2AF2
chr23730262637302679-CDS,intron-Distal,intron-Proximal3.9794010.36594HepG2BCLAF1
chr23729585237295905-CDS,intron-Distal5.130117.39496HepG2BCLAF1
chr23729741537297437-CDS,intron-Distal3.512874.09885HepG2BCLAF1
chr23723538837235531-intron-Distal3.466224.10408K562KHSRP
chr23726788837267995-intron-Distal5.312535.95026HepG2U2AF2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for HEATR5B is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for HEATR5B is not available on ENCORE database.

  • 82 RBPs can affect the levels of HEATR5B.  








The Knockdown/knockout RNA-Seq assay for HEATR5B is not available on ENCORE database.





82 RBPs can affect the gene expression of HEATR5B :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
HEATR5BENSG00000008869.71103.83430663.621000.7340015.2182014.03570HepG2ACO1
HEATR5BENSG00000008869.7954.49890666.694600.517606.990805.83190HepG2AKAP8L
HEATR5BENSG00000008869.71550.48170763.674301.0216018.4409017.09760HepG2BOP1
HEATR5BENSG00000008869.7991.52680707.433400.487004.991703.99230HepG2CALR
HEATR5BENSG00000008869.7924.39570619.903500.576404.834803.82780HepG2CIRBP
HEATR5BENSG00000008869.7846.01290663.423500.350603.785303.02970HepG2CKAP4
HEATR5BENSG00000008869.7957.95210676.498500.501802.508801.78260HepG2CNOT7
HEATR5BENSG00000008869.7874.91860613.729800.511407.597506.33040HepG2DDX19B
HEATR5BENSG00000008869.71101.85450701.383700.651607.490706.43080HepG2DDX21
HEATR5BENSG00000008869.71352.72360755.381700.840509.968108.84700HepG2DDX3X
HEATR5BENSG00000008869.7981.94500689.223400.510603.235802.40930HepG2DDX55
HEATR5BENSG00000008869.7542.95060669.34670-0.301902.148001.52020HepG2DNAJC21
HEATR5BENSG00000008869.7830.03180615.253400.431902.817401.88830HepG2EEF2
HEATR5BENSG00000008869.7873.83190645.861600.436002.466101.42680HepG2AGO1
HEATR5BENSG00000008869.7714.15670499.431100.515903.645502.61550HepG2EIF3D
HEATR5BENSG00000008869.71357.24350689.331700.9773011.9719010.66700HepG2EIF4A3
HEATR5BENSG00000008869.71038.81180671.218300.630004.167903.33250HepG2EIF4B
HEATR5BENSG00000008869.71641.103301247.657400.395306.109805.27650HepG2ETF1
HEATR5BENSG00000008869.71411.54110828.057800.769408.164606.92000HepG2FIP1L1
HEATR5BENSG00000008869.7641.18560419.953600.610405.199304.13260HepG2FUBP3
HEATR5BENSG00000008869.71136.89900645.220900.817108.846307.69200HepG2G3BP1
HEATR5BENSG00000008869.7953.75240685.047000.477303.568302.55080HepG2G3BP2
HEATR5BENSG00000008869.7987.02140661.268400.577705.151403.75570HepG2GNB2L1
HEATR5BENSG00000008869.71046.27240850.676300.298502.485801.59390HepG2HNRNPA2B1
HEATR5BENSG00000008869.71017.47690751.671500.436703.539602.76280HepG2HNRNPC
HEATR5BENSG00000008869.71062.10110843.316300.332703.582702.82230HepG2HNRNPL
HEATR5BENSG00000008869.71122.45140758.439300.565405.141504.31080HepG2HNRNPLL
HEATR5BENSG00000008869.7724.03350887.10820-0.293102.192201.54310HepG2IGF2BP1
HEATR5BENSG00000008869.7874.04730655.836000.414302.671002.00610HepG2IGF2BP2
HEATR5BENSG00000008869.71139.07490615.542100.887803.662002.52890HepG2IGF2BP3
HEATR5BENSG00000008869.7946.88310670.390500.498105.075704.00540HepG2MSI2
HEATR5BENSG00000008869.71360.51080716.190800.9256011.5754010.32200HepG2NCBP2
HEATR5BENSG00000008869.7936.15270618.371900.598203.048202.11380HepG2PABPC1
HEATR5BENSG00000008869.71084.75700637.759600.766208.059206.84310HepG2PABPC4
HEATR5BENSG00000008869.7864.75070666.547300.375503.798403.11080HepG2PCBP1
HEATR5BENSG00000008869.7517.68720665.99510-0.363402.907402.15470HepG2PPIL4
HEATR5BENSG00000008869.7827.37590531.613800.638105.119704.05620HepG2PRPF8
HEATR5BENSG00000008869.71080.73080678.260100.6720011.0117010.06090HepG2PTBP1
HEATR5BENSG00000008869.71230.77290930.062800.404105.812305.01710HepG2PUM1
HEATR5BENSG00000008869.71163.32140929.420200.323702.476801.84220HepG2PUM2
HEATR5BENSG00000008869.7927.19520675.933200.455905.997805.15330HepG2PUS1
HEATR5BENSG00000008869.71210.26210734.522800.7203011.5307010.38480HepG2QKI
HEATR5BENSG00000008869.71608.27600759.558301.082207.092605.99200HepG2RAVER1
HEATR5BENSG00000008869.71725.543801042.819400.7265015.4635014.44030HepG2RBM22
HEATR5BENSG00000008869.71054.51640666.645400.661508.312107.19210HepG2RBM25
HEATR5BENSG00000008869.71093.81680754.819000.535107.449506.63830HepG2NELFE
HEATR5BENSG00000008869.7896.29140703.046500.350203.406102.73100HepG2RECQL
HEATR5BENSG00000008869.71032.78730745.947400.469302.406201.52480HepG2RPS10
HEATR5BENSG00000008869.7713.63810485.987500.554204.941004.14690HepG2RPS19
HEATR5BENSG00000008869.7963.85760720.444100.419803.096802.24970HepG2RPS2
HEATR5BENSG00000008869.7858.87150525.869500.707605.665904.57780HepG2RRP9
HEATR5BENSG00000008869.7736.59790487.734000.594704.865203.63230HepG2SERBP1
HEATR5BENSG00000008869.71850.701901177.841400.6518016.6990015.74100HepG2SRFBP1
HEATR5BENSG00000008869.71574.66370737.047801.0951034.1629032.90690HepG2SRSF1
HEATR5BENSG00000008869.71219.22190807.762000.593904.393303.10550HepG2SRSF3
HEATR5BENSG00000008869.71211.37850865.046100.485706.654305.74060HepG2SRSF5
HEATR5BENSG00000008869.71011.60030599.642300.7544014.9901013.88970HepG2SRSF9
HEATR5BENSG00000008869.71366.010301022.672000.417506.379405.65930HepG2SSB
HEATR5BENSG00000008869.71319.62520983.856500.423505.903405.05730HepG2SUCLG1
HEATR5BENSG00000008869.71097.35660662.534600.7279012.2311011.18100HepG2TAF15
HEATR5BENSG00000008869.71185.32260708.471900.742409.247108.08970HepG2U2AF1
HEATR5BENSG00000008869.71250.20870905.904600.464602.246101.49650HepG2UBE2L3
HEATR5BENSG00000008869.71002.56670773.538400.374104.454003.60440HepG2UPF1
HEATR5BENSG00000008869.7486.63080675.38290-0.472903.046002.28660HepG2XRN2
HEATR5BENSG00000008869.7862.70610668.913000.367004.015603.23090HepG2ZC3H8
HEATR5BENSG00000008869.71222.99870850.743400.5235010.006309.12840HepG2ZNF622
HEATR5BENSG00000008869.7807.66830624.273200.371502.461301.35470K562AARS
HEATR5BENSG00000008869.7992.159901273.49950-0.360202.641202.06460K562AQR
HEATR5BENSG00000008869.7590.07920786.75280-0.415003.826802.22530K562BCCIP
HEATR5BENSG00000008869.7562.20000760.25000-0.435404.356203.13470K562BCLAF1
HEATR5BENSG00000008869.71677.566701213.031400.467707.886106.86220K562DDX47
HEATR5BENSG00000008869.71029.720401346.85500-0.387304.537603.37680K562DKC1
HEATR5BENSG00000008869.7617.03260786.34440-0.349803.085601.79530K562EIF2S1
HEATR5BENSG00000008869.7512.03960747.93850-0.546704.831103.74410K562EIF4A3
HEATR5BENSG00000008869.7810.938101225.21780-0.595406.621005.44580K562GRSF1
HEATR5BENSG00000008869.7880.84880682.872100.367202.690602.10040K562HNRNPC
HEATR5BENSG00000008869.71427.845701096.221300.381203.619002.38900K562HNRNPL
HEATR5BENSG00000008869.7907.323301217.61730-0.424403.521802.62730K562HSPD1
HEATR5BENSG00000008869.7656.254501061.43010-0.693709.068207.49440K562MAGOH
HEATR5BENSG00000008869.71240.586001488.03910-0.262402.153301.36690K562MBNL1
HEATR5BENSG00000008869.7597.979101019.40990-0.769609.391807.63520K562PPIG
HEATR5BENSG00000008869.7439.16050612.29190-0.479503.214302.22710K562PSIP1
HEATR5BENSG00000008869.71373.833101838.35730-0.420205.599204.21510K562PUM2
HEATR5BENSG00000008869.7737.51160988.86370-0.423103.464002.51790K562RBM22
HEATR5BENSG00000008869.7819.71960636.386200.365102.003001.31370K562RPS19
HEATR5BENSG00000008869.7764.103501003.13660-0.392703.905902.94630K562SF3A3
HEATR5BENSG00000008869.7724.344601023.16470-0.498304.297903.40940K562TARDBP
HEATR5BENSG00000008869.7768.35760986.95500-0.361203.000902.14300K562TIA1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for HEATR5B is not available on ENCORE database.





12 RBPs can affect the splicing of HEATR5B :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEHEATR5BENSG00000008869.7chr2-372177903721794237215788372160023722772837227956-0.423000.000260.00697excludedK562SF3B4
SEHEATR5BENSG00000008869.7chr2-372177903721794237215788372160023722772837227956-0.340000.000260.01265excludedK562PRPF8
SEHEATR5BENSG00000008869.7chr2-372177903721794237215788372160023722772837227956-0.456000.000060.00188excludedHepG2U2AF1
SEHEATR5BENSG00000008869.7chr2-373087433730889337306262373064743731043137310579-0.072000.000680.01474excludedHepG2U2AF1
SEHEATR5BENSG00000008869.7chr2-372177903721794237215788372160023722772837227956-0.221000.003820.08578excludedK562AKAP8L
SEHEATR5BENSG00000008869.7chr2-372177903721794237215788372160023722772837227956-0.454000.000100.01900excludedHepG2HNRNPM
SEHEATR5BENSG00000008869.7chr2-3721779037217942372157883721600237227728372279560.335000.000060.01944includedHepG2DKC1
SEHEATR5BENSG00000008869.7chr2-372177903721794237215788372160023722772837227956-0.369000.000530.00712excludedK562AQR
SEHEATR5BENSG00000008869.7chr2-372177903721794237215788372160023722772837227956-0.296000.006480.07566excludedK562PUS1
SEHEATR5BENSG00000008869.7chr2-373087433730889837306262373064743731043137310579-0.058000.003070.04262excludedK562PUS1
SEHEATR5BENSG00000008869.7chr2-3723502837235189372341923723444737235753372359910.126000.000090.00315includedK562U2AF1
SEHEATR5BENSG00000008869.7chr2-372177903721794237215788372160023722772837227956-0.419000.000160.00498excludedK562U2AF1
SEHEATR5BENSG00000008869.7chr2-372177903721794237215788372160023722772837227956-0.258000.000060.01751excludedK562EIF4G2
SEHEATR5BENSG00000008869.7chr2-372177903721794237215788372160023722772837227956-0.326000.000060.00387excludedK562UTP18
SEHEATR5BENSG00000008869.7chr2-372177903721794237215788372160023722772837227956-0.335000.003670.05647excludedK562U2AF2
SEHEATR5BENSG00000008869.7chr2-372177903721794237215788372160023722772837227956-0.328000.000490.09119excludedHepG2FUS
A3SSHEATR5BENSG00000008869.7chr2-3729289737293073372928973729305337295823372960730.165000.005820.03303longerK562AQR
A3SSHEATR5BENSG00000008869.7chr2-3726827537268478372682753726843537276795372769860.130000.000570.00420longerK562AQR
A3SSHEATR5BENSG00000008869.7chr2-3728445937284636372844593728462337285593372857030.102000.004270.02515longerK562AQR
A3SSHEATR5BENSG00000008869.7chr2-372327743723290237232774372328713723419237234447-0.090000.010560.05540shorterK562AQR
MXEHEATR5BENSG00000008869.7chr2-3721578837216002372177903721794237208152372089373722772837227956-0.268000.002420.045102includedK562PRPF8

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for HEATR5B is not avaliable on ENCORE database.