PNPLA4

General Information

Gene Name       : PNPLA4
Gene ID             : ENSG00000006757.11
Essential Gene : No

Functions

Localization

Domains (AlphaFold: PNPLA4)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PNPLA4ENSG00000006757.1124.2823.8224.05ENCSR000AEF
HepG2PNPLA4ENSG00000006757.1116.6921.1718.93ENCSR985KAT
K562PNPLA4ENSG00000006757.1123.7331.5227.62ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PNPLA4 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PNPLA4 RNA is bound by 3 proteins.  







eCLIP assay for PNPLA4 is not avaliable on ENCORE database.





3 proteins are bound to PNPLA4 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chrX78953287895443-5'-UTR,intron-Distal5.314656.69401K562DDX3X
chrX78688157868858-CDS,intron-Distal3.210283.67697K562YBX3
chrX78898217889890-CDS,intron-Distal,intron-Proximal3.798363.67607K562YBX3
chrX78949907895016-intron-Distal6.8647512.61397K562RPS3
chrX78949897895015-intron-Distal6.7212815.71559HepG2DDX3X
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PNPLA4 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PNPLA4 is not available on ENCORE database.

  • 43 RBPs can affect the levels of PNPLA4.  








The Knockdown/knockout RNA-Seq assay for PNPLA4 is not available on ENCORE database.





43 RBPs can affect the gene expression of PNPLA4 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PNPLA4ENSG00000006757.7571.23700415.926900.457702.313701.82300HepG2AKAP1
PNPLA4ENSG00000006757.7505.23280326.971700.627704.365003.40610HepG2CIRBP
PNPLA4ENSG00000006757.7125.67440198.63190-0.660402.836202.14130HepG2CPSF6
PNPLA4ENSG00000006757.7195.89280122.206500.680602.711501.64460HepG2CSTF2
PNPLA4ENSG00000006757.7288.82750211.983900.446202.438401.65040HepG2DDX19B
PNPLA4ENSG00000006757.7311.32600210.647400.563502.999602.29590HepG2DDX21
PNPLA4ENSG00000006757.7612.99770398.463000.621304.424303.64720HepG2DDX3X
PNPLA4ENSG00000006757.7113.12160194.58260-0.782503.325802.48800HepG2DDX55
PNPLA4ENSG00000006757.7221.48580342.20190-0.627603.038802.39390HepG2DDX6
PNPLA4ENSG00000006757.7283.24330194.592600.541503.129902.38650HepG2DNAJC21
PNPLA4ENSG00000006757.7162.87460329.05240-1.014605.702104.86840HepG2EIF2S1
PNPLA4ENSG00000006757.7555.85150363.682900.611903.941303.18270HepG2EIF4A3
PNPLA4ENSG00000006757.7242.60490342.70290-0.498302.666901.89580HepG2FUBP3
PNPLA4ENSG00000006757.7326.83590196.456600.734304.427403.63490HepG2HNRNPA1
PNPLA4ENSG00000006757.7300.17510218.514100.458001.952301.35850HepG2HNRNPC
PNPLA4ENSG00000006757.7175.98470344.47270-0.968906.492005.45290HepG2HNRNPK
PNPLA4ENSG00000006757.7290.06960221.731100.387502.021501.38350HepG2ILF2
PNPLA4ENSG00000006757.7237.06040351.89700-0.569904.229803.50690HepG2PCBP1
PNPLA4ENSG00000006757.7382.73420269.117300.508003.676302.79680HepG2PRPF4
PNPLA4ENSG00000006757.7223.66670358.04710-0.678805.547604.82830HepG2PTBP1
PNPLA4ENSG00000006757.7159.86430245.72350-0.620201.926901.32810HepG2RAVER1
PNPLA4ENSG00000006757.7434.94370330.128300.397702.521302.02050HepG2RBM22
PNPLA4ENSG00000006757.7295.87500398.48970-0.429602.732602.19400HepG2NELFE
PNPLA4ENSG00000006757.7250.47390371.10710-0.567204.085403.35450HepG2RECQL
PNPLA4ENSG00000006757.7540.85070382.285600.500503.639002.87380HepG2RPLP0
PNPLA4ENSG00000006757.7342.02970212.669200.685404.098003.25500HepG2SF3B1
PNPLA4ENSG00000006757.7277.82840372.81130-0.424302.346801.79630HepG2SF3B4
PNPLA4ENSG00000006757.7179.96750316.55550-0.814707.229206.41230HepG2SRSF9
PNPLA4ENSG00000006757.7483.33900323.751400.578005.475004.80150HepG2SSB
PNPLA4ENSG00000006757.7272.84460349.71210-0.358101.937001.45350HepG2TAF15
PNPLA4ENSG00000006757.7173.38740321.38340-0.890307.425306.06930HepG2TIA1
PNPLA4ENSG00000006757.7286.22110212.807800.427502.291901.76880HepG2TRIM56
PNPLA4ENSG00000006757.7164.17660317.25160-0.950405.425804.23280HepG2UBE2L3
PNPLA4ENSG00000006757.7297.21430190.663400.640402.614301.90970HepG2XRN2
PNPLA4ENSG00000006757.7244.65690345.66040-0.498602.667901.51050K562AARS
PNPLA4ENSG00000006757.7334.55370492.57680-0.558103.828703.16080K562AQR
PNPLA4ENSG00000006757.7544.36670342.786300.667205.667204.42660K562FIP1L1
PNPLA4ENSG00000006757.7172.55600264.52770-0.616402.687501.99300K562G3BP2
PNPLA4ENSG00000006757.7253.80220378.05240-0.574903.524802.86130K562HNRNPC
PNPLA4ENSG00000006757.7746.92460464.707200.684506.555305.34520K562HSPD1
PNPLA4ENSG00000006757.7651.55160373.773000.801603.327202.21300K562PABPN1
PNPLA4ENSG00000006757.7611.35290389.169500.651505.750504.49440K562PPIG
PNPLA4ENSG00000006757.7207.16660290.79460-0.489202.476401.68430K562RBM22
PNPLA4ENSG00000006757.7176.96550264.72510-0.581003.247502.37900K562U2AF2
PNPLA4ENSG00000006757.7620.86270854.86600-0.461402.992401.52960K562UBE2L3
PNPLA4ENSG00000006757.7550.44130420.909900.387003.304402.38760K562WDR43
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PNPLA4 is not available on ENCORE database.





1 RBPs can affect the splicing of PNPLA4 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
MXEPNPLA4ENSG00000006757.7chrX-78897537889889788992178901397880068788013478939807894173-0.202000.000090.003282includedK562DROSHA

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PNPLA4 is not avaliable on ENCORE database.