NR1H4

General Information

Gene Name       : NR1H4
Gene ID             : ENSG00000012504.14
Essential Gene : No

Functions

Localization

Domains (AlphaFold: NR1H4)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878NR1H4ENSG00000012504.140.000.000.00ENCSR000AEF
HepG2NR1H4ENSG00000012504.1415.3532.7324.04ENCSR985KAT
K562NR1H4ENSG00000012504.140.000.030.01ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for NR1H4 is not avaliable on ENCORE database.



Proteins bound to RNA
  • NR1H4 RNA is bound by 26 proteins.  







eCLIP assay for NR1H4 is not avaliable on ENCORE database.





26 proteins are bound to NR1H4 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr12100886355100886416+3'-UTR,5'-UTR,intron-Proximal3.223326.70817HepG2ZNF800
chr12100886276100886359+3'-UTR,5'-UTR,intron-Proximal3.953096.46431HepG2TRA2A
chr12100957498100957614+3'-UTR3.562203.13224HepG2ZC3H11A
chr12100886329100886416+3'-UTR,5'-UTR,intron-Proximal3.3023316.04706HepG2PPIG
chr12100934544100934605+3'-UTR,CDS,intron-Proximal3.136514.16939HepG2PPIG
chr12100886351100886416+3'-UTR,5'-UTR,intron-Proximal3.056089.43113HepG2BCLAF1
chr12100955506100955674+3'-UTR,CDS,intron-Distal,intron-Proximal3.256924.89503HepG2KHSRP
chr12100934484100934594+3'-UTR,CDS5.6131710.39778HepG2GRWD1
chr12100887049100887103+3'-UTR,5'-UTR,CDS4.1906112.93761HepG2BCLAF1
chr12100887047100887103+3'-UTR,5'-UTR,CDS,intron-Proximal3.623035.74981HepG2GRWD1
chr12100955638100955699+3'-UTR,CDS,intron-Proximal3.844519.27521HepG2U2AF2
chr12100934531100934599+3'-UTR,CDS,intron-Proximal4.295344.69957HepG2SRSF7
chr12100934583100934643+3'-UTR,CDS,intron-Proximal3.025897.18673HepG2PRPF8
chr12100934454100934561+3'-UTR,CDS4.3953611.11870HepG2BCLAF1
chr12100886271100886326+3'-UTR,5'-UTR,intron-Proximal3.656127.25157HepG2AQR
chr12100867829100867878+5'-UTR,intron-Proximal4.669839.38298HepG2PRPF8
chr12100867781100867871+5'-UTR,intron-Proximal3.901036.19659HepG2AQR
chr12100867658100867757+5'-UTR4.890298.64103HepG2GRWD1
chr12100926317100926371+CDS,intron-Distal3.533763.80299HepG2GRWD1
chr12100928797100928842+CDS,intron-Proximal4.784526.26248HepG2PRPF8
chr12100904892100904957+CDS,intron-Proximal3.6992014.39387HepG2PRPF8
chr12100926303100926372+CDS,intron-Distal3.121336.34055HepG2PPIG
chr12100904562100904620+CDS3.649364.45064HepG2GRWD1
chr12100926348100926396+CDS,intron-Distal,intron-Proximal4.005363.86479HepG2PRPF8
chr12100904646100904754+CDS4.005043.23099HepG2UCHL5
chr12100904562100904606+CDS3.124075.00751HepG2BCLAF1
chr12100926297100926378+CDS,intron-Distal,intron-Proximal4.3460911.55759HepG2BCLAF1
chr12100923428100923548+intron-Distal4.520243.27829HepG2MATR3
chr12100943728100943754+intron-Distal5.929659.03229HepG2QKI
chr12100910943100911003+intron-Distal3.632426.44854HepG2PCBP2
chr12100923312100923379+intron-Distal4.264104.51735HepG2QKI
chr12100923221100923368+intron-Distal3.394164.01234HepG2HNRNPL
chr12100923040100923123+intron-Distal3.770573.59395HepG2PTBP1
chr12100904251100904343+intron-Distal3.806666.17334HepG2U2AF2
chr12100956788100956846+intron-Distal4.856448.27172HepG2TIA1
chr12100927233100927294+intron-Distal4.755816.37401HepG2RBFOX2
chr12100871941100872006+intron-Distal4.949055.57311HepG2RBFOX2
chr12100942431100942533+intron-Distal3.276084.11679HepG2SFPQ
chr12100940822100940913+intron-Distal4.6561412.38260HepG2PTBP1
chr12100934604100934768+intron-Distal,intron-Proximal3.846777.20544HepG2KHSRP
chr12100939905100939956+intron-Distal3.599024.92676HepG2XPO5
chr12100949426100949515+intron-Distal4.402703.19026HepG2HNRNPL
chr12100940520100940614+intron-Distal3.048425.09290HepG2QKI
chr12100943698100943728+intron-Distal4.604129.78867HepG2QKI
chr12100937318100937406+intron-Distal3.239873.84724HepG2IGF2BP1
chr12100937341100937412+intron-Distal3.785614.16875HepG2SRSF7
chr12100910924100911001+intron-Distal3.332386.62781HepG2QKI
chr12100951642100951690+intron-Distal3.960264.59145HepG2XPO5
chr12100869417100869500+intron-Distal4.6109416.03863HepG2QKI
chr12100913105100913176+intron-Distal3.893933.63122HepG2PRPF4
chr12100894327100894470+intron-Distal4.127583.18711HepG2ILF3
chr12100923427100923526+intron-Distal3.896103.41738HepG2PTBP1
chr12100934632100934664+intron-Proximal3.393484.42776HepG2BUD13
chr12100934624100934690+intron-Proximal3.317496.59650HepG2RBM22
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for NR1H4 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for NR1H4 is not available on ENCORE database.

  • 135 RBPs can affect the levels of NR1H4.  








The Knockdown/knockout RNA-Seq assay for NR1H4 is not available on ENCORE database.





135 RBPs can affect the gene expression of NR1H4 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
NR1H4ENSG00000012504.9302.08990708.67530-1.2301017.9607015.61190HepG2AATF
NR1H4ENSG00000012504.92063.92570903.635401.1915019.1068017.03510HepG2ABCF1
NR1H4ENSG00000012504.9500.24950704.88750-0.494705.758004.94330HepG2ACO1
NR1H4ENSG00000012504.91264.94630613.153701.0447016.4551014.35680HepG2ADAR
NR1H4ENSG00000012504.9169.110201843.92620-3.4467023.5290022.14560HepG2AKAP1
NR1H4ENSG00000012504.9260.72490848.33710-1.7021021.5939019.00640HepG2AKAP8
NR1H4ENSG00000012504.91053.95480708.252900.573408.846507.57150HepG2AKAP8L
NR1H4ENSG00000012504.9569.973401093.01220-0.9393021.2296019.65260HepG2AUH
NR1H4ENSG00000012504.9473.69850768.28000-0.697705.483804.15030HepG2BCCIP
NR1H4ENSG00000012504.9591.17700780.23580-0.400302.818802.21510HepG2BOP1
NR1H4ENSG00000012504.9548.33170771.83190-0.493203.640802.77230HepG2CALR
NR1H4ENSG00000012504.92897.498001449.578500.9991018.1040016.34240HepG2CIRBP
NR1H4ENSG00000012504.9845.08440704.798800.261801.998901.42150HepG2CKAP4
NR1H4ENSG00000012504.9248.72350664.42190-1.417603.772902.87360HepG2CNOT7
NR1H4ENSG00000012504.9478.53220716.27900-0.581904.638203.76870HepG2CPSF6
NR1H4ENSG00000012504.9485.17660628.76260-0.374002.882301.84280HepG2YBX3
NR1H4ENSG00000012504.9824.67620474.513300.797308.678706.95060HepG2CSTF2
NR1H4ENSG00000012504.9330.90300939.54010-1.5055039.4160037.56630HepG2CELF1
NR1H4ENSG00000012504.91108.92560651.949600.7662017.8693016.18370HepG2DDX19B
NR1H4ENSG00000012504.9461.26680629.67540-0.449002.662101.52780HepG2DDX1
NR1H4ENSG00000012504.91190.38520782.234300.605706.720605.71210HepG2DDX21
NR1H4ENSG00000012504.91481.67750765.185900.9532018.2798016.16260HepG2DDX24
NR1H4ENSG00000012504.91319.60420706.755200.900708.984206.83700HepG2DDX27
NR1H4ENSG00000012504.9955.728001766.56120-0.886304.141503.38930HepG2DDX3X
NR1H4ENSG00000012504.9282.35740563.82360-0.9977012.128209.73390HepG2DDX52
NR1H4ENSG00000012504.9250.31610755.39630-1.5935022.2749020.40740HepG2DDX55
NR1H4ENSG00000012504.9199.23450813.39400-2.0295022.0890019.63210HepG2DDX59
NR1H4ENSG00000012504.9902.000301516.99590-0.750003.434302.75400HepG2DDX6
NR1H4ENSG00000012504.92037.90240674.403001.5953073.5866071.37990HepG2DKC1
NR1H4ENSG00000012504.9269.24770617.44800-1.1974020.0247018.31510HepG2DNAJC21
NR1H4ENSG00000012504.9393.66220611.92270-0.636408.443107.38010HepG2DNAJC2
NR1H4ENSG00000012504.91128.89800672.699900.746808.103106.61560HepG2EEF2
NR1H4ENSG00000012504.9391.10600560.78540-0.519903.453802.21150HepG2EFTUD2
NR1H4ENSG00000012504.9270.305301458.83780-2.4322015.2861013.96310HepG2EIF2S1
NR1H4ENSG00000012504.91533.01430738.500201.0536022.7668020.31410HepG2EIF3G
NR1H4ENSG00000012504.9816.72730553.761200.560504.138301.93160HepG2EIF3H
NR1H4ENSG00000012504.92130.971301612.435300.402202.019501.47090HepG2EIF4A3
NR1H4ENSG00000012504.91931.60260996.668000.9545029.2404027.14600HepG2EIF4G1
NR1H4ENSG00000012504.91270.64310954.754000.412302.588301.79930HepG2EIF4G2
NR1H4ENSG00000012504.91098.08630783.108700.487603.364402.16480HepG2ESF1
NR1H4ENSG00000012504.9206.16100488.06900-1.2433017.1454014.31820HepG2FAM120A
NR1H4ENSG00000012504.9274.90100745.28890-1.4389025.9178023.16800HepG2FASTKD2
NR1H4ENSG00000012504.9264.78810912.56190-1.785107.193906.01320HepG2FIP1L1
NR1H4ENSG00000012504.91081.43340628.733500.782307.730705.76700HepG2FKBP4
NR1H4ENSG00000012504.91351.88270945.145600.516303.931201.95820HepG2FMR1
NR1H4ENSG00000012504.91765.84390717.548201.299105.456904.03690HepG2FTO
NR1H4ENSG00000012504.9410.35310943.48850-1.2011016.7794014.92720HepG2FUBP3
NR1H4ENSG00000012504.9243.47840964.54280-1.9861020.2513017.74360HepG2FUS
NR1H4ENSG00000012504.9384.008201508.86800-1.9743012.0312010.69160HepG2G3BP1
NR1H4ENSG00000012504.9703.93280486.208300.533804.092902.99050HepG2GEMIN5
NR1H4ENSG00000012504.91203.66200811.903400.568004.644703.82810HepG2GPKOW
NR1H4ENSG00000012504.9271.66380614.90210-1.178502.848701.71890HepG2GRSF1
NR1H4ENSG00000012504.9418.22540908.71360-1.119508.080605.60030HepG2GTF2F1
NR1H4ENSG00000012504.9445.43150673.00490-0.595407.526106.01340HepG2HDGF
NR1H4ENSG00000012504.9551.23340923.85700-0.745004.373302.59830HepG2HLTF
NR1H4ENSG00000012504.91237.75670623.362500.989509.295408.21210HepG2HNRNPA1
NR1H4ENSG00000012504.9753.80560928.46370-0.300702.725001.79560HepG2HNRNPA2B1
NR1H4ENSG00000012504.9562.109201526.94360-1.441708.717607.52870HepG2HNRNPK
NR1H4ENSG00000012504.9580.90040920.32470-0.6639012.1852010.86610HepG2HNRNPL
NR1H4ENSG00000012504.91206.99990774.819300.639406.103105.20790HepG2HNRNPLL
NR1H4ENSG00000012504.9410.94680629.92540-0.616202.177201.33380HepG2HNRNPM
NR1H4ENSG00000012504.9273.41190688.76900-1.3329029.2279027.43800HepG2HNRNPU
NR1H4ENSG00000012504.91443.07000800.299400.8504016.3796014.78030HepG2IGF2BP1
NR1H4ENSG00000012504.9453.077501438.90670-1.667108.667706.99880HepG2IGF2BP3
NR1H4ENSG00000012504.9286.83510703.55890-1.2944023.2645021.38880HepG2ILF2
NR1H4ENSG00000012504.9446.91490668.62970-0.581204.187402.18840HepG2CCAR2
NR1H4ENSG00000012504.91423.98070935.707400.605704.757303.65870HepG2LARP4
NR1H4ENSG00000012504.9229.33670739.86850-1.6898025.3272022.35990HepG2LARP7
NR1H4ENSG00000012504.92176.782001626.693400.420202.593701.95790HepG2MAGOH
NR1H4ENSG00000012504.9106.79410571.51330-2.4200024.9854022.12740HepG2METAP2
NR1H4ENSG00000012504.9470.53070739.03940-0.651402.045201.34460HepG2MSI2
NR1H4ENSG00000012504.9851.988301674.55420-0.974904.735403.91950HepG2NCBP2
NR1H4ENSG00000012504.9344.902501001.80750-1.5383039.5771037.06900HepG2NOL12
NR1H4ENSG00000012504.91218.21500687.065200.8261010.803609.40530HepG2NSUN2
NR1H4ENSG00000012504.9490.72730751.68490-0.615204.486001.91270HepG2NUSAP1
NR1H4ENSG00000012504.9167.26100607.01450-1.859605.349604.08520HepG2PABPC1
NR1H4ENSG00000012504.9579.345201491.75580-1.364507.277706.11780HepG2PABPC4
NR1H4ENSG00000012504.9209.98930681.79370-1.6990039.9583037.51190HepG2PARN
NR1H4ENSG00000012504.9954.379101557.97380-0.7070016.1637014.89670HepG2PCBP1
NR1H4ENSG00000012504.91610.66970913.129400.818706.866805.29560HepG2PCBP2
NR1H4ENSG00000012504.9848.86520711.462100.254601.962301.30290HepG2PRPF4
NR1H4ENSG00000012504.91510.72810959.971000.654104.440802.91730HepG2PRPF6
NR1H4ENSG00000012504.9567.550001585.27310-1.4819056.5185054.75180HepG2PTBP1
NR1H4ENSG00000012504.91378.96830956.295400.528003.313802.67020HepG2PUF60
NR1H4ENSG00000012504.9606.339301015.12920-0.7435016.1039014.91470HepG2PUM1
NR1H4ENSG00000012504.9488.809401014.40050-1.0533019.7259018.02910HepG2PUM2
NR1H4ENSG00000012504.9849.16900717.983100.242001.994301.45250HepG2PUS1
NR1H4ENSG00000012504.9331.862501716.93990-2.37120104.47910101.60500HepG2QKI
NR1H4ENSG00000012504.9335.31440881.33470-1.3942012.0600010.66660HepG2RAVER1
NR1H4ENSG00000012504.9312.17400888.51700-1.5090020.4425018.48790HepG2RBM15
NR1H4ENSG00000012504.9314.787901048.89700-1.7364050.4308048.75660HepG2RBM22
NR1H4ENSG00000012504.9698.288101558.21440-1.1580026.2320024.29360HepG2RBM25
NR1H4ENSG00000012504.9655.97100892.13250-0.443602.670601.69480HepG2RBM27
NR1H4ENSG00000012504.91055.59450724.448200.543004.780103.37730HepG2RCC2
NR1H4ENSG00000012504.91334.861301764.27620-0.402406.095405.34490HepG2NELFE
NR1H4ENSG00000012504.91264.565401643.14810-0.377805.455504.62670HepG2RECQL
NR1H4ENSG00000012504.92700.30500875.441001.6249050.3544048.33290HepG2RPLP0
NR1H4ENSG00000012504.91499.95580865.477000.793306.267304.88340HepG2RPS10
NR1H4ENSG00000012504.91180.82000822.833200.521005.123104.05560HepG2RPS2
NR1H4ENSG00000012504.91862.54200666.360901.4828022.6538020.46210HepG2RPS3A
NR1H4ENSG00000012504.9312.01430576.33710-0.885307.400306.18820HepG2RRP9
NR1H4ENSG00000012504.9302.63360613.39360-1.0192017.2111015.80180HepG2SAFB2
NR1H4ENSG00000012504.91017.71580533.293700.9322012.1334010.23920HepG2SERBP1
NR1H4ENSG00000012504.91546.507401154.341800.421802.452401.81850HepG2SF3A3
NR1H4ENSG00000012504.91595.88500766.886501.0572018.8390017.17340HepG2SF3B1
NR1H4ENSG00000012504.9978.301101650.51600-0.7546018.1540016.84360HepG2SF3B4
NR1H4ENSG00000012504.9545.36550715.34460-0.391404.205803.44250HepG2SMN1
NR1H4ENSG00000012504.9459.38180897.85690-0.966808.169806.48070HepG2SMNDC1
NR1H4ENSG00000012504.9574.12610856.96050-0.577902.953001.31710HepG2SND1
NR1H4ENSG00000012504.9373.99490938.39230-1.327205.251503.30200HepG2SNRNP200
NR1H4ENSG00000012504.9266.07100853.30700-1.681309.532008.09130HepG2SNRNP70
NR1H4ENSG00000012504.9327.985301184.68320-1.8528070.2481068.59660HepG2SRFBP1
NR1H4ENSG00000012504.9514.62520944.17770-0.8755017.0262015.66080HepG2SRSF5
NR1H4ENSG00000012504.9979.84100798.456100.295202.905302.19470HepG2SRSF7
NR1H4ENSG00000012504.9698.520001401.54560-1.0046029.8497028.40990HepG2SRSF9
NR1H4ENSG00000012504.92858.449801028.572601.4745084.4975082.68090HepG2SSB
NR1H4ENSG00000012504.9524.80160920.28270-0.810307.620305.64800HepG2SSRP1
NR1H4ENSG00000012504.9534.10360931.99620-0.803206.576004.56710HepG2SUGP2
NR1H4ENSG00000012504.91086.644101548.43990-0.510908.025207.15010HepG2TAF15
NR1H4ENSG00000012504.9978.09980755.353900.372702.600101.89410HepG2TARDBP
NR1H4ENSG00000012504.91782.25950903.938900.979304.862203.47780HepG2TBRG4
NR1H4ENSG00000012504.9357.71530503.99500-0.494603.001501.96490HepG2TFIP11
NR1H4ENSG00000012504.9697.769901422.85600-1.0280021.6479019.39050HepG2TIA1
NR1H4ENSG00000012504.9940.56700669.358700.490705.239304.59630HepG2TIAL1
NR1H4ENSG00000012504.9169.02240675.24470-1.9982024.4946023.02080HepG2TRIM56
NR1H4ENSG00000012504.9390.930501092.13010-1.482205.898504.40800HepG2U2AF2
NR1H4ENSG00000012504.9271.39980988.84190-1.8653030.7808028.15050HepG2UBE2L3
NR1H4ENSG00000012504.9828.306401023.72130-0.305603.172102.43470HepG2UPF1
NR1H4ENSG00000012504.91880.84330688.492901.4498019.9753017.31590HepG2UPF2
NR1H4ENSG00000012504.9462.24410866.41210-0.906405.344003.58130HepG2XRCC5
NR1H4ENSG00000012504.9596.75830969.09540-0.699505.019603.61910HepG2XRCC6
NR1H4ENSG00000012504.91223.80880740.221500.725207.245006.08380HepG2XRN2
NR1H4ENSG00000012504.9961.69880702.128500.453706.152605.21310HepG2ZC3H8
NR1H4ENSG00000012504.9578.870701125.90220-0.9598027.0034025.74220HepG2ZNF622
NR1H4ENSG00000012504.99.153800.0000099999.999902.467701.90010K562HNRNPC
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for NR1H4 is not available on ENCORE database.





9 RBPs can affect the splicing of NR1H4 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SENR1H4ENSG00000012504.9chr12+1008936301008938021008870211008871801008993521008995740.442000.000410.01224includedHepG2SRSF1
SENR1H4ENSG00000012504.9chr12+1008936301008938021008870781008871801008993521008995740.462000.002280.08917includedHepG2PCBP1
SENR1H4ENSG00000012504.9chr12+100926235100926388100904555100904921100928667100928801-0.180000.000320.01561excludedHepG2HNRNPC
MXENR1H4ENSG00000012504.9chr12+1009045551009049211009262351009263881008870471008871801009286671009288010.283000.000810.043521includedHepG2SRSF9
MXENR1H4ENSG00000012504.9chr12+1009045551009049211009262351009263881008870471008871801009286671009288010.151000.008390.070581includedHepG2SFPQ
MXENR1H4ENSG00000012504.9chr12+1009045551009049211009262351009263881008870471008871801009286671009288010.349000.000080.000971includedHepG2U2AF2
MXENR1H4ENSG00000012504.9chr12+1009045551009049211009262351009263761008870471008871801009286671009288010.348000.000740.006341includedHepG2U2AF2
MXENR1H4ENSG00000012504.9chr12+100904555100904921100926235100926388100887047100887180100928667100928801-0.418000.000020.004182includedHepG2DROSHA
MXENR1H4ENSG00000012504.9chr12+1009045551009049211009262351009263881008870471008871801009286671009288010.167000.001260.021931includedHepG2HNRNPUL1
MXENR1H4ENSG00000012504.9chr12+1009047041009049211009262351009263881008870471008871801009286671009288010.183000.000710.076281includedHepG2XRCC6

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for NR1H4 is not avaliable on ENCORE database.