EXTL3

General Information

Gene Name       : EXTL3
Gene ID             : ENSG00000012232.8
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: EXTL3)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878EXTL3ENSG00000012232.810.098.759.42ENCSR000AEF
HepG2EXTL3ENSG00000012232.812.6510.3111.48ENCSR985KAT
K562EXTL3ENSG00000012232.89.4210.7310.07ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for EXTL3 is not avaliable on ENCORE database.



Proteins bound to RNA
  • EXTL3 RNA is bound by 4 proteins.  







eCLIP assay for EXTL3 is not avaliable on ENCORE database.





4 proteins are bound to EXTL3 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr82861024428610338+3'-UTR5.081486.57498HepG2PCBP2
chr82861087528610952+3'-UTR4.504144.22051K562UPF1
chr82857097628571068+3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal4.946175.82881K562DDX3X
chr82860955428609614+3'-UTR,intron-Distal5.074827.60978K562UPF1
chr82855902828559098+5'-UTR,intron-Distal4.669916.30794HepG2DDX3X
chr82855909828559178+5'-UTR,intron-Distal,intron-Proximal4.241788.97908HepG2DDX3X
chr82856169028561848+intron-Distal4.092613.05187HepG2QKI
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for EXTL3 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for EXTL3 is not available on ENCORE database.

  • 90 RBPs can affect the levels of EXTL3.  








The Knockdown/knockout RNA-Seq assay for EXTL3 is not available on ENCORE database.





90 RBPs can affect the gene expression of EXTL3 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
EXTL3ENSG00000012232.41277.98550872.037800.551307.120406.23840HepG2ACO1
EXTL3ENSG00000012232.41596.815301118.777500.513203.863603.25060HepG2AKAP1
EXTL3ENSG00000012232.4964.90720726.167300.410002.483301.49480HepG2AKAP8
EXTL3ENSG00000012232.4668.76020536.483600.317901.995201.33190HepG2CALR
EXTL3ENSG00000012232.41178.73960876.026600.428102.482301.56570HepG2CCAR1
EXTL3ENSG00000012232.4653.85560879.45780-0.427602.905502.11320HepG2CIRBP
EXTL3ENSG00000012232.41206.72760871.876700.468807.833606.82310HepG2CKAP4
EXTL3ENSG00000012232.4257.34080597.69230-1.2157014.5929013.16210HepG2CPSF6
EXTL3ENSG00000012232.4683.12550837.82560-0.294502.266701.67510HepG2CELF1
EXTL3ENSG00000012232.41076.95930900.819100.257602.667101.93660HepG2DAZAP1
EXTL3ENSG00000012232.4650.99760806.52310-0.309103.037502.16690HepG2DDX19B
EXTL3ENSG00000012232.4874.95250649.981700.428703.333402.59370HepG2DDX21
EXTL3ENSG00000012232.4816.097301071.65060-0.393002.567601.96310HepG2DDX3X
EXTL3ENSG00000012232.41430.21560757.529100.916806.236705.13080HepG2DDX55
EXTL3ENSG00000012232.4337.35770678.72470-1.008506.291304.84450HepG2DDX59
EXTL3ENSG00000012232.4423.34760598.53350-0.499602.746701.64510HepG2AGO1
EXTL3ENSG00000012232.41145.60440884.962400.372302.407001.85240HepG2EIF2S1
EXTL3ENSG00000012232.41535.59790952.264700.689305.377204.43980HepG2EIF4B
EXTL3ENSG00000012232.41763.996401358.731400.376505.160404.38510HepG2ETF1
EXTL3ENSG00000012232.41059.69790852.161900.314402.357601.58690HepG2EWSR1
EXTL3ENSG00000012232.41601.65910847.925900.9175011.196309.79430HepG2FIP1L1
EXTL3ENSG00000012232.4271.03860598.72390-1.143405.382603.97200HepG2FTO
EXTL3ENSG00000012232.4587.74160402.460100.546203.592002.55850HepG2GEMIN5
EXTL3ENSG00000012232.4332.99260677.52150-1.0248010.217509.04240HepG2GPKOW
EXTL3ENSG00000012232.41007.93390827.902200.283802.528801.63040HepG2HNRNPA2B1
EXTL3ENSG00000012232.4804.482901025.23980-0.349803.678502.86160HepG2HNRNPF
EXTL3ENSG00000012232.41156.71630927.121000.319102.095901.48220HepG2HNRNPK
EXTL3ENSG00000012232.4695.04430820.56240-0.239501.995001.41100HepG2HNRNPL
EXTL3ENSG00000012232.4768.66470585.009700.393802.936001.95580HepG2HNRNPM
EXTL3ENSG00000012232.4856.63530642.839600.414102.850502.23550HepG2HNRNPU
EXTL3ENSG00000012232.4801.451001009.56960-0.333102.727302.00880HepG2IGF2BP1
EXTL3ENSG00000012232.4471.45580656.63650-0.478005.697104.67800HepG2ILF2
EXTL3ENSG00000012232.4819.93420473.062200.793404.673903.32740HepG2METAP2
EXTL3ENSG00000012232.41209.24460686.219600.8173012.1931010.61500HepG2MSI2
EXTL3ENSG00000012232.4742.254101016.07110-0.453003.105502.43690HepG2NCBP2
EXTL3ENSG00000012232.4303.40010573.31660-0.918108.513207.25310HepG2NSUN2
EXTL3ENSG00000012232.4370.88540692.40080-0.9006014.4264012.87720HepG2PRPF4
EXTL3ENSG00000012232.4777.75420584.210400.412702.269601.53510HepG2PRPF8
EXTL3ENSG00000012232.41233.74940934.549800.400605.172904.47340HepG2PTBP1
EXTL3ENSG00000012232.41150.65880905.196400.346104.861504.12080HepG2PUM1
EXTL3ENSG00000012232.41037.98120888.231300.224702.018301.47320HepG2PUS1
EXTL3ENSG00000012232.4619.281801012.15540-0.7088010.218009.12450HepG2QKI
EXTL3ENSG00000012232.4317.10480629.85620-0.990106.032605.01810HepG2RAVER1
EXTL3ENSG00000012232.42535.772101135.653001.1588042.2104040.65750HepG2RBM22
EXTL3ENSG00000012232.4631.64920808.50520-0.356102.336101.43320HepG2RBM27
EXTL3ENSG00000012232.4848.50330618.973200.454902.232501.38260HepG2RPS10
EXTL3ENSG00000012232.4719.30280439.872200.709407.447506.49790HepG2RPS19
EXTL3ENSG00000012232.41040.44070745.636000.480603.668502.75120HepG2RPS2
EXTL3ENSG00000012232.4850.22090577.889100.556903.595602.71460HepG2RRP9
EXTL3ENSG00000012232.4270.64000572.46740-1.0808017.8503016.41880HepG2SAFB2
EXTL3ENSG00000012232.4637.93700441.429000.531103.773002.67320HepG2SERBP1
EXTL3ENSG00000012232.41179.29520863.715200.449202.555701.90760HepG2SF3A3
EXTL3ENSG00000012232.4796.75590639.973200.316001.907201.31410HepG2SF3B1
EXTL3ENSG00000012232.4851.12050667.577300.350303.859303.12020HepG2SMN1
EXTL3ENSG00000012232.4964.42390642.986000.584803.929102.77010HepG2SMNDC1
EXTL3ENSG00000012232.4273.93630712.08440-1.3782012.8295011.16250HepG2SNRNP70
EXTL3ENSG00000012232.42044.365501282.687200.6724018.1032017.11920HepG2SRFBP1
EXTL3ENSG00000012232.41195.742101015.595700.235502.097101.66940HepG2SRSF1
EXTL3ENSG00000012232.4984.59070688.628800.515703.281602.18120HepG2SRSF3
EXTL3ENSG00000012232.41202.71240841.937800.514408.053707.05740HepG2SRSF5
EXTL3ENSG00000012232.4624.81110826.23680-0.403104.293103.63400HepG2SRSF9
EXTL3ENSG00000012232.4887.478301113.69160-0.327603.587603.02030HepG2SSB
EXTL3ENSG00000012232.41635.97330957.498900.772705.764104.92640HepG2SUCLG1
EXTL3ENSG00000012232.4686.23250912.84290-0.411704.049603.39160HepG2TAF15
EXTL3ENSG00000012232.4898.08910630.232400.510904.268903.39440HepG2TARDBP
EXTL3ENSG00000012232.41238.48080725.324900.771809.219208.06470HepG2U2AF1
EXTL3ENSG00000012232.4223.54300445.41530-0.994609.326807.93470HepG2UCHL5
EXTL3ENSG00000012232.4585.97950765.98330-0.386503.603302.82170HepG2UPF1
EXTL3ENSG00000012232.4499.10440690.36560-0.468002.669801.68240HepG2UPF2
EXTL3ENSG00000012232.41008.28880739.526900.447105.750704.93880HepG2UTP3
EXTL3ENSG00000012232.4470.22440742.29230-0.658605.746704.71490HepG2XRN2
EXTL3ENSG00000012232.4368.29200683.32510-0.8917015.2421013.87170HepG2ZC3H8
EXTL3ENSG00000012232.41102.02990842.435100.387405.542804.83760HepG2ZNF622
EXTL3ENSG00000012232.41251.30580861.826200.537908.815407.87760K562AGGF1
EXTL3ENSG00000012232.41086.40450896.779300.276601.941301.39100K562AKAP8L
EXTL3ENSG00000012232.41116.63440830.463800.427103.414702.77750K562AQR
EXTL3ENSG00000012232.4998.836901270.58180-0.347203.158402.11850K562CELF1
EXTL3ENSG00000012232.4857.40850664.558400.367503.442002.65340K562EIF2S2
EXTL3ENSG00000012232.4813.12680618.394000.394902.997002.14540K562EIF4A3
EXTL3ENSG00000012232.4695.84350521.209600.416803.137401.58570K562G3BP1
EXTL3ENSG00000012232.4237.04780396.62320-0.742604.398403.46250K562G3BP2
EXTL3ENSG00000012232.4696.62100885.61030-0.346302.447001.73450K562GRSF1
EXTL3ENSG00000012232.4826.04950534.311500.628402.502401.35900K562HNRNPA2B1
EXTL3ENSG00000012232.4340.78970485.95380-0.511903.342002.69410K562HNRNPC
EXTL3ENSG00000012232.4801.19420572.934100.483704.311603.25930K562MAGOH
EXTL3ENSG00000012232.4815.34480467.433100.802603.782802.57450K562PABPN1
EXTL3ENSG00000012232.4949.73410555.786800.772903.310901.66060K562PPP1R8
EXTL3ENSG00000012232.4735.96050502.437200.550604.005203.10260K562PRPF8
EXTL3ENSG00000012232.41125.41820889.287200.339602.508401.98540K562PUS1
EXTL3ENSG00000012232.41080.30620866.535900.318002.966602.35650K562RBM15
EXTL3ENSG00000012232.4292.00670397.49720-0.444902.400201.48100K562RCC2
EXTL3ENSG00000012232.4956.57350427.515101.161805.932803.95780K562SF1
EXTL3ENSG00000012232.4867.50430490.919600.821303.659702.17770K562SNRNP200
EXTL3ENSG00000012232.4689.25160532.737400.371502.547101.76540K562TIA1
EXTL3ENSG00000012232.4384.31770514.78100-0.421702.443901.49280K562UCHL5
EXTL3ENSG00000012232.4847.36640640.271600.404204.313503.43520K562UPF1
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for EXTL3 is not available on ENCORE database.





1 RBPs can affect the splicing of EXTL3 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
A3SSEXTL3ENSG00000012232.4chr8+2857307428573127285731012857312728570973285710670.142000.012070.06207longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for EXTL3 is not avaliable on ENCORE database.