METTL13

General Information

Gene Name       : METTL13
Gene ID             : ENSG00000010165.19
Essential Gene : No

Functions

Localization

Domains (AlphaFold: METTL13)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878METTL13ENSG00000010165.1923.8124.8024.30ENCSR000AEF
HepG2METTL13ENSG00000010165.1927.0928.1127.60ENCSR985KAT
K562METTL13ENSG00000010165.1944.2753.0848.67ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for METTL13 is not avaliable on ENCORE database.



Proteins bound to RNA
  • METTL13 RNA is bound by 9 proteins.  







eCLIP assay for METTL13 is not avaliable on ENCORE database.





9 proteins are bound to METTL13 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr1171750829171750968+5'-UTR,CDS,intron-Proximal4.144664.25489HepG2NCBP2
chr1171750859171751088+5'-UTR,CDS,intron-Distal,intron-Proximal4.538785.13332K562FUS
chr1171750867171750982+5'-UTR,CDS,intron-Proximal3.406936.57172K562DDX3X
chr1171755020171755086+CDS,intron-Proximal4.803825.61356K562FMR1
chr1171753211171753315+CDS,intron-Distal,intron-Proximal3.958703.98564K562LIN28B
chr1171765614171765694+CDS,intron-Distal,intron-Proximal3.275877.18285K562BUD13
chr1171753318171753407+CDS,intron-Distal4.258633.36385K562UCHL5
chr1171753052171753122+CDS3.292393.02345K562ZNF622
chr1171759869171760053+intron-Distal5.026257.91159K562KHSRP
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for METTL13 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for METTL13 is not available on ENCORE database.

  • 72 RBPs can affect the levels of METTL13.  








The Knockdown/knockout RNA-Seq assay for METTL13 is not available on ENCORE database.





72 RBPs can affect the gene expression of METTL13 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
METTL13ENSG00000010165.15742.83220510.590000.540806.889406.01670HepG2ACO1
METTL13ENSG00000010165.151102.41810659.274000.741606.555005.77530HepG2AKAP1
METTL13ENSG00000010165.15346.42050589.63860-0.767305.290904.08490HepG2BCLAF1
METTL13ENSG00000010165.15680.80180518.260800.393502.291601.58360HepG2CIRBP
METTL13ENSG00000010165.15257.28300361.25460-0.489702.395101.74860HepG2CPSF6
METTL13ENSG00000010165.15592.25050472.232300.326602.774501.93950HepG2DDX19B
METTL13ENSG00000010165.15269.64690410.23240-0.605402.304101.41470HepG2DDX59
METTL13ENSG00000010165.15313.09060459.74120-0.554204.550403.66630HepG2DNAJC21
METTL13ENSG00000010165.15376.79430521.53210-0.469002.554401.98460HepG2EIF2S1
METTL13ENSG00000010165.15423.01060306.445900.465002.451901.59560HepG2EIF3D
METTL13ENSG00000010165.15747.51090576.369900.375001.972401.42910HepG2EIF4A3
METTL13ENSG00000010165.15798.06940561.147200.508002.731902.04650HepG2EIF4B
METTL13ENSG00000010165.15587.04690810.73390-0.465804.884303.82390HepG2EIF4G1
METTL13ENSG00000010165.15569.59140776.61280-0.447303.055002.20020HepG2EIF4G2
METTL13ENSG00000010165.15852.430501013.23310-0.249302.220101.67170HepG2ETF1
METTL13ENSG00000010165.15666.19530498.956300.416903.071502.19480HepG2EWSR1
METTL13ENSG00000010165.15386.73470555.30010-0.521902.759201.49210HepG2FKBP4
METTL13ENSG00000010165.15828.34830581.485800.510403.673302.88460HepG2FXR1
METTL13ENSG00000010165.15566.16940755.19900-0.415603.728802.66840HepG2HNRNPA2B1
METTL13ENSG00000010165.15464.40860643.79580-0.471204.755003.84670HepG2HNRNPF
METTL13ENSG00000010165.15604.07930748.44580-0.309202.610801.95570HepG2HNRNPL
METTL13ENSG00000010165.15230.03510390.79410-0.764605.020504.19860HepG2HNRNPLL
METTL13ENSG00000010165.15477.52480633.95200-0.408803.188702.41580HepG2IGF2BP1
METTL13ENSG00000010165.15429.50830523.87200-0.286502.264001.59220HepG2ILF2
METTL13ENSG00000010165.15260.57010398.58210-0.613202.613701.67540HepG2MTPAP
METTL13ENSG00000010165.15625.74900814.77630-0.380803.047902.24800HepG2NOL12
METTL13ENSG00000010165.15220.48520346.52130-0.652303.594502.74190HepG2NSUN2
METTL13ENSG00000010165.15350.82230457.43230-0.382802.537301.82820HepG2PPIL4
METTL13ENSG00000010165.15372.90520514.76260-0.465102.236401.50710HepG2PRPF8
METTL13ENSG00000010165.15529.06220777.80820-0.556004.851304.08940HepG2PUF60
METTL13ENSG00000010165.15447.03190631.80760-0.499104.234403.48560HepG2QKI
METTL13ENSG00000010165.151250.13180846.867100.561806.378005.66940HepG2RBM22
METTL13ENSG00000010165.15418.76500573.40690-0.453403.199702.47970HepG2RBM25
METTL13ENSG00000010165.15626.37260464.941300.429902.340601.36890HepG2RCC2
METTL13ENSG00000010165.15289.00510447.63800-0.631203.147202.14440HepG2RPS10
METTL13ENSG00000010165.15367.18690456.72690-0.314802.011901.44850HepG2SAFB2
METTL13ENSG00000010165.15731.56620454.342200.687104.910703.99620HepG2SF3A3
METTL13ENSG00000010165.15274.08910386.80290-0.497002.590801.90670HepG2SF3B1
METTL13ENSG00000010165.15482.14480607.36710-0.333102.363501.81150HepG2SF3B4
METTL13ENSG00000010165.15501.38100745.87590-0.573007.248106.19630HepG2SLBP
METTL13ENSG00000010165.15447.13170632.51850-0.500405.417104.49710HepG2SRSF7
METTL13ENSG00000010165.15399.48170515.76140-0.368602.542802.00830HepG2SRSF9
METTL13ENSG00000010165.15635.11550830.43440-0.386804.086903.48960HepG2SSB
METTL13ENSG00000010165.15326.22660664.13750-1.025609.012707.90670HepG2SUPV3L1
METTL13ENSG00000010165.15243.82020380.93110-0.643704.007203.15470HepG2TARDBP
METTL13ENSG00000010165.15379.19480498.34380-0.394202.602802.11530HepG2TIAL1
METTL13ENSG00000010165.15378.03360502.79620-0.411503.311202.70650HepG2TRIM56
METTL13ENSG00000010165.15562.68050438.758800.358801.978301.43770HepG2U2AF1
METTL13ENSG00000010165.15648.27620389.015300.736709.752808.73910HepG2UTP3
METTL13ENSG00000010165.15275.31410455.27830-0.725704.446902.76770HepG2ZRANB2
METTL13ENSG00000010165.151136.288601414.06690-0.315503.933202.77450K562BCLAF1
METTL13ENSG00000010165.15469.66250669.74470-0.512003.786102.51410K562CCAR1
METTL13ENSG00000010165.15585.01370741.60560-0.342202.375301.64350K562CPSF6
METTL13ENSG00000010165.151491.283001953.39250-0.389405.606704.63600K562EIF2S2
METTL13ENSG00000010165.151105.15670754.864100.549907.252805.97450K562EIF3G
METTL13ENSG00000010165.15591.56140834.52510-0.496403.581402.27380K562FKBP4
METTL13ENSG00000010165.15569.10220754.62620-0.407102.664201.82550K562FMR1
METTL13ENSG00000010165.15443.12640639.63990-0.529503.540902.49710K562FTO
METTL13ENSG00000010165.15490.30650667.36820-0.444802.712301.38900K562FUS
METTL13ENSG00000010165.151739.50580830.385501.0667031.1724029.27600K562FXR1
METTL13ENSG00000010165.15427.46720678.79760-0.667204.508003.55930K562G3BP2
METTL13ENSG00000010165.15998.980401348.11070-0.432403.154501.61690K562GEMIN5
METTL13ENSG00000010165.15869.755701152.14290-0.405604.480703.03460K562GLRX3
METTL13ENSG00000010165.151337.828701658.38510-0.309902.818901.73710K562HNRNPA1
METTL13ENSG00000010165.15675.91400960.98470-0.507704.848704.07930K562HNRNPC
METTL13ENSG00000010165.151338.801301744.85120-0.382203.187302.33650K562HSPD1
METTL13ENSG00000010165.151248.310401019.303800.292302.258801.49550K562MAGOH
METTL13ENSG00000010165.15867.018501211.32950-0.482507.072505.83100K562MTPAP
METTL13ENSG00000010165.151065.630901347.27970-0.338302.168601.43200K562PCBP3
METTL13ENSG00000010165.151363.942401817.34380-0.414003.294001.58070K562PKM
METTL13ENSG00000010165.151295.24660990.362500.387103.801703.03510K562PTBP1
METTL13ENSG00000010165.15560.71420737.72510-0.395802.713501.46160K562SLBP
METTL13ENSG00000010165.15855.742601267.07950-0.566304.730003.37080K562SUPV3L1
METTL13ENSG00000010165.151513.901201036.525900.546407.557406.18960K562SYNCRIP
METTL13ENSG00000010165.151509.473801847.83960-0.291803.892802.38060K562TROVE2
METTL13ENSG00000010165.15827.514201340.97140-0.696407.802706.02220K562UCHL5
METTL13ENSG00000010165.151236.778101427.07350-0.206501.979901.36530K562UPF1
METTL13ENSG00000010165.151033.008801365.36340-0.402403.006601.72660K562XRN2
METTL13ENSG00000010165.151725.251302296.36540-0.412503.262702.31590K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for METTL13 is not available on ENCORE database.





16 RBPs can affect the splicing of METTL13 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEMETTL13ENSG00000010165.15chr1+1717595911717597561717568741717570701717611561717613750.198000.000020.00070includedK562SRSF1
SEMETTL13ENSG00000010165.15chr1+1717645691717647511717635351717636671717656211717660430.057000.000570.01313includedK562SRSF1
SEMETTL13ENSG00000010165.15chr1+171751127171751260171750803171750935171752879171753179-0.189000.003680.05940excludedK562SRSF1
SEMETTL13ENSG00000010165.15chr1+171759591171759756171756874171757070171761156171761375-0.158000.000660.02259excludedK562AKAP8L
SEMETTL13ENSG00000010165.15chr1+1717527601717527971717507871717509351717528791717536390.177000.004250.04067includedK562AQR
SEMETTL13ENSG00000010165.15chr1+1717645691717647511717634341717636671717656211717661010.051000.000000.00003includedK562AQR
SEMETTL13ENSG00000010165.15chr1+1717595911717597561717568741717570701717611561717613750.185000.000000.00003includedK562FXR1
SEMETTL13ENSG00000010165.15chr1+171759591171759756171756874171757070171761156171761375-0.190000.000030.04037excludedK562KHDRBS1
SEMETTL13ENSG00000010165.15chr1+171759591171759756171756874171757070171761156171761375-0.142000.002840.04002excludedK562PUS1
SEMETTL13ENSG00000010165.15chr1+171751127171751260171750803171750935171752879171753179-0.146000.000000.00334excludedK562APOBEC3C
SEMETTL13ENSG00000010165.15chr1+171759591171759756171756874171757070171761156171761375-0.191000.000020.03630excludedK562ILF3
SEMETTL13ENSG00000010165.15chr1+171759591171759756171756874171757070171761156171761375-0.151000.000030.00383excludedK562HNRNPL
SEMETTL13ENSG00000010165.15chr1+1717595911717597561717568741717570701717611561717613750.163000.000590.07265includedK562RBM22
SEMETTL13ENSG00000010165.15chr1+171759591171759756171756874171757070171761156171761375-0.290000.000040.00136excludedK562U2AF2
SEMETTL13ENSG00000010165.15chr1+1717595911717597561717568741717570701717611561717613750.177000.000050.00331includedK562TARDBP
SEMETTL13ENSG00000010165.15chr1+171759591171759756171756874171757070171761156171761375-0.190000.002500.05439excludedK562RBM15
SEMETTL13ENSG00000010165.15chr1+171759591171759756171756874171757070171761156171761375-0.204000.000090.00407excludedK562AGGF1
SEMETTL13ENSG00000010165.15chr1+1717595911717597561717568741717570701717611561717613750.217000.000010.00093includedK562HNRNPK
SEMETTL13ENSG00000010165.15chr1+1717595911717597561717568741717570701717611561717613750.105000.000250.05736includedK562SAFB
A3SSMETTL13ENSG00000010165.15chr1+1717635011717636671717635351717636671717611561717613750.112000.000000.00000longerK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for METTL13 is not avaliable on ENCORE database.