PAF1

General Information

Gene Name       : PAF1
Gene ID             : ENSG00000006712.14
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: PAF1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878PAF1ENSG00000006712.1424.1830.1127.14ENCSR000AEF
HepG2PAF1ENSG00000006712.1450.5335.1942.86ENCSR985KAT
K562PAF1ENSG00000006712.1429.7030.2729.98ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for PAF1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • PAF1 RNA is bound by 11 proteins.  







eCLIP assay for PAF1 is not avaliable on ENCORE database.





11 proteins are bound to PAF1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr193987712339877186-3'-UTR,CDS,intron-Distal5.4052010.65697K562UCHL5
chr193988141839881469-5'-UTR,CDS,intron-Distal4.540078.52787K562AQR
chr193988148839881624-5'-UTR,CDS,intron-Distal4.862528.41344HepG2GRWD1
chr193988165239881776-5'-UTR,intron-Distal,intron-Proximal4.511056.30252K562DDX3X
chr193987931039879370-CDS,intron-Distal,intron-Proximal5.244457.36555K562SF3B4
chr193987953639879635-CDS,intron-Distal,intron-Proximal4.262458.78209HepG2PRPF8
chr193987694239876999-CDS,intron-Distal,intron-Proximal4.166787.79539K562UCHL5
chr193988027939880372-CDS,intron-Distal,intron-Proximal3.819343.27203K562IGF2BP2
chr193987923039879282-CDS,intron-Distal3.972045.37538K562ZNF622
chr193988088439880958-CDS,intron-Distal,intron-Proximal4.385417.53589K562AQR
chr193987688739876933-CDS,intron-Distal,intron-Proximal4.982147.34525K562ZNF622
chr193987960839879718-CDS,intron-Distal,intron-Proximal4.4630219.78410K562EFTUD2
chr193987688639876932-CDS,intron-Distal,intron-Proximal3.321405.39086K562UCHL5
chr193987921239879249-CDS,intron-Distal3.471834.22563K562UCHL5
chr193987899039879036-CDS,intron-Distal4.696135.14565K562UCHL5
chr193987998539880087-CDS,intron-Distal,intron-Proximal5.2004123.78146K562EFTUD2
chr193987686239877015-CDS,intron-Distal,intron-Proximal3.314105.76664HepG2G3BP1
chr193987949739879550-CDS,intron-Distal,intron-Proximal4.9089116.05232K562EFTUD2
chr193987898939879045-CDS,intron-Distal4.844335.94412K562ZNF622
chr193988083339880969-CDS,intron-Distal,intron-Proximal5.8475112.49979HepG2AQR
chr193988141339881468-CDS,intron-Distal3.176804.71929HepG2PRPF8
chr193987950239879549-CDS,intron-Distal,intron-Proximal3.681685.82046K562SF3B4
chr193988079639880891-CDS,intron-Distal,intron-Proximal4.305613.31384K562XRN2
chr193987699939877043-CDS,intron-Distal,intron-Proximal3.436507.32655K562UCHL5
chr193987983639879873-CDS,intron-Distal,intron-Proximal4.508069.23680K562EFTUD2
chr193987951339879558-intron-Distal,intron-Proximal5.334435.99517HepG2EFTUD2
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for PAF1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for PAF1 is not available on ENCORE database.

  • 70 RBPs can affect the levels of PAF1.  








The Knockdown/knockout RNA-Seq assay for PAF1 is not available on ENCORE database.





70 RBPs can affect the gene expression of PAF1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
PAF1ENSG00000006712.101077.81970890.546300.275302.817902.20560HepG2ACO1
PAF1ENSG00000006712.101623.975601013.957700.679406.305705.53980HepG2AKAP1
PAF1ENSG00000006712.101181.73410894.753700.401205.089004.07510HepG2AKAP8L
PAF1ENSG00000006712.101067.88680838.954200.348002.177801.47700HepG2ASCC1
PAF1ENSG00000006712.101496.996001874.59500-0.324502.689902.09920HepG2BOP1
PAF1ENSG00000006712.101095.18050797.067700.458303.505502.64140HepG2CIRBP
PAF1ENSG00000006712.10563.73210890.38080-0.6594011.5341010.36440HepG2CKAP4
PAF1ENSG00000006712.10840.68820531.186000.662303.826302.92100HepG2CNOT7
PAF1ENSG00000006712.101332.203801720.94760-0.369403.002902.29020HepG2CPSF6
PAF1ENSG00000006712.10699.03590823.64060-0.236602.042601.31670HepG2DDX19B
PAF1ENSG00000006712.101364.15730971.272000.490003.938503.20320HepG2DDX3X
PAF1ENSG00000006712.101250.48300929.597000.427703.205102.21880HepG2EEF2
PAF1ENSG00000006712.101193.33640863.043400.467402.654701.98000HepG2EIF4B
PAF1ENSG00000006712.10963.193101212.37170-0.331902.204701.47230HepG2EIF4G2
PAF1ENSG00000006712.101177.62750894.376300.396802.772802.08010HepG2FXR1
PAF1ENSG00000006712.10980.690001178.94690-0.265602.292201.43310HepG2HNRNPA2B1
PAF1ENSG00000006712.101180.324701450.98140-0.297803.145502.38420HepG2HNRNPF
PAF1ENSG00000006712.10856.651901168.42470-0.447806.666905.66510HepG2HNRNPL
PAF1ENSG00000006712.101058.80520776.983300.446406.063305.19520HepG2HNRNPU
PAF1ENSG00000006712.101097.50730843.280300.380002.559101.90760HepG2IGF2BP2
PAF1ENSG00000006712.101006.65610793.660500.342904.291303.39790HepG2ILF2
PAF1ENSG00000006712.101353.15080899.683700.588704.926704.10550HepG2MATR3
PAF1ENSG00000006712.101211.94710920.866000.396202.678602.05470HepG2NCBP2
PAF1ENSG00000006712.10767.80450485.623100.660803.444102.44640HepG2PABPC1
PAF1ENSG00000006712.10815.06560624.036400.385203.225701.89600HepG2PKM
PAF1ENSG00000006712.10483.92090642.33440-0.408602.487401.71950HepG2PRPF8
PAF1ENSG00000006712.10896.750701288.05450-0.522406.210005.21960HepG2PUM2
PAF1ENSG00000006712.10757.847701198.44170-0.6612010.661509.78980HepG2RBM22
PAF1ENSG00000006712.101263.922301562.90840-0.306302.181401.56590HepG2RPLP0
PAF1ENSG00000006712.10919.24750734.286900.324002.278501.71500HepG2RPS19
PAF1ENSG00000006712.10886.00600691.930100.356603.412302.71020HepG2SAFB2
PAF1ENSG00000006712.101403.193701842.59810-0.393003.664702.86180HepG2SF3B1
PAF1ENSG00000006712.10773.30370918.24340-0.247801.966901.45440HepG2SF3B4
PAF1ENSG00000006712.101229.68870806.894100.6077013.0040011.76930HepG2SMN1
PAF1ENSG00000006712.101220.65320958.423500.348803.903403.36560HepG2SRSF1
PAF1ENSG00000006712.101434.031601198.953800.258202.060301.51030HepG2SRSF5
PAF1ENSG00000006712.101091.135701425.50570-0.385604.995504.10210HepG2SRSF7
PAF1ENSG00000006712.10654.05730464.433900.493802.830601.71480HepG2STIP1
PAF1ENSG00000006712.101572.828201363.487700.206002.158301.59640HepG2SUCLG1
PAF1ENSG00000006712.101075.60670829.075600.375501.893901.32040HepG2SUPV3L1
PAF1ENSG00000006712.10660.62690861.40210-0.382903.715203.08140HepG2TAF15
PAF1ENSG00000006712.101350.018401814.75430-0.426804.052003.19370HepG2TARDBP
PAF1ENSG00000006712.10939.55580754.934100.315502.605902.11810HepG2TIAL1
PAF1ENSG00000006712.101988.931401563.255800.347302.934602.28850HepG2U2AF1
PAF1ENSG00000006712.102035.151101372.520500.5682012.6919011.57180K562AGGF1
PAF1ENSG00000006712.101913.910601508.249100.343503.210302.13250K562AKAP8
PAF1ENSG00000006712.102178.215301428.183700.608908.706407.47920K562AKAP8L
PAF1ENSG00000006712.102005.844001568.553400.354703.427902.03830K562APOBEC3C
PAF1ENSG00000006712.102121.306701319.425900.6849010.145109.12950K562AQR
PAF1ENSG00000006712.101869.481301498.534700.319003.857702.76390K562ATP5C1
PAF1ENSG00000006712.10929.11100691.075000.426903.138101.99860K562CCAR1
PAF1ENSG00000006712.102603.947501800.626500.5321011.9597010.70720K562DDX47
PAF1ENSG00000006712.101004.66830773.660800.376802.581501.30210K562DHX30
PAF1ENSG00000006712.101023.88320702.941500.542502.861701.83840K562EIF3A
PAF1ENSG00000006712.10725.73310504.709600.523904.954603.90530K562EIF3G
PAF1ENSG00000006712.10896.23480726.540800.302702.063701.35140K562EIF4A3
PAF1ENSG00000006712.10801.74300654.317700.293002.350801.30910K562EIF4B
PAF1ENSG00000006712.10399.86800560.35140-0.486802.034701.44120K562G3BP2
PAF1ENSG00000006712.101900.242101559.522800.285002.243901.52810K562GPKOW
PAF1ENSG00000006712.101658.862501281.404300.372402.502801.61950K562HNRNPM
PAF1ENSG00000006712.101375.938101069.178600.363804.012602.92820K562HNRNPU
PAF1ENSG00000006712.101979.767701515.611100.385304.662903.54340K562KIF1C
PAF1ENSG00000006712.10751.954301331.63760-0.824507.588605.95550K562KRR1
PAF1ENSG00000006712.101815.674601450.852300.323502.929701.81620K562MAK16
PAF1ENSG00000006712.102565.926501697.874000.595709.449107.57020K562MBNL1
PAF1ENSG00000006712.101528.699101190.091000.361102.065101.32650K562NAA15
PAF1ENSG00000006712.10798.20730634.193600.331702.193401.32730K562PCBP2
PAF1ENSG00000006712.10932.47650649.902700.520704.037803.13150K562PRPF8
PAF1ENSG00000006712.101093.36750890.103900.296602.086501.31180K562PSIP1
PAF1ENSG00000006712.10962.27650692.581900.474404.816203.96230K562PTBP1
PAF1ENSG00000006712.102538.380801416.267000.8417013.8707012.69970K562PUS1
PAF1ENSG00000006712.102069.515001380.021100.584507.271306.34100K562RBM15
PAF1ENSG00000006712.10975.41340678.992200.522505.411204.42870K562SRSF1
PAF1ENSG00000006712.101393.522401117.381300.318502.956002.10490K562SYNCRIP
PAF1ENSG00000006712.10935.24930687.117500.444703.421202.63070K562TARDBP
PAF1ENSG00000006712.10726.52860542.533800.421202.404501.39570K562U2AF1
PAF1ENSG00000006712.102166.661501436.047600.593302.907301.57430K562UTP18
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for PAF1 is not available on ENCORE database.





9 RBPs can affect the splicing of PAF1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEPAF1ENSG00000006712.10chr19-398808993988107139880525398808013988145739881722-0.060000.004300.06715excludedHepG2U2AF1
SEPAF1ENSG00000006712.10chr19-3988027939880417398801193988018639880708398808010.092000.003010.09972includedHepG2SFPQ
SEPAF1ENSG00000006712.10chr19-398808993988107139880525398808013988145739881722-0.081000.000460.01643excludedHepG2SF3A3
A3SSPAF1ENSG00000006712.10chr19-398807083988092939880708398808013988145739881794-0.096000.000440.03690shorterHepG2SF3A3
A3SSPAF1ENSG00000006712.10chr19-3988027939880481398802793988040139880708398808010.103000.000000.00000longerK562AQR
A3SSPAF1ENSG00000006712.10chr19-3987733339877527398773333987743939878978398791070.086000.000000.00000longerK562AQR
RIPAF1ENSG00000006712.10chr19-3987993339880177398799333988002339880119398801770.078000.000000.00003includedK562PUS1
RIPAF1ENSG00000006712.10chr19-3988070839880929398807083988080139880899398809290.078000.000000.00000includedK562PUS1
RIPAF1ENSG00000006712.10chr19-3988011939880401398801193988018639880279398804010.065000.001930.02463includedK562PRPF8
RIPAF1ENSG00000006712.10chr19-3987993339880177398799333988002339880119398801770.061000.000270.00412includedK562RBM15
RIPAF1ENSG00000006712.10chr19-3988011939880401398801193988018639880279398804010.067000.001720.01906includedK562EFTUD2
RIPAF1ENSG00000006712.10chr19-3988011939880401398801193988018639880279398804010.256000.000000.00000includedK562AQR
RIPAF1ENSG00000006712.10chr19-3987958639879816398795863987965539879732398798160.160000.000000.00000includedK562AQR
RIPAF1ENSG00000006712.10chr19-3988070839880929398807083988080139880899398809290.121000.000000.00000includedK562AQR
RIPAF1ENSG00000006712.10chr19-3987993339880177398799333988002339880119398801770.087000.000000.00000includedK562AQR
MXEPAF1ENSG00000006712.10chr19-3988027939880401398807083988080139880119398801863988089939880929-0.126000.000740.089092includedK562UTP3

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for PAF1 is not avaliable on ENCORE database.