POLA2

General Information

Gene Name : POLA2
Gene ID : ENSG00000014138.8
Essential Gene : Yes

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: POLA2)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	POLA2	ENSG00000014138.8	92.21	82.11	87.16	ENCSR000AEF
HepG2	POLA2	ENSG00000014138.8	17.89	19.05	18.47	ENCSR985KAT
K562	POLA2	ENSG00000014138.8	66.97	76.04	71.50	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for POLA2 is not avaliable on ENCORE database.

Proteins bound to RNA

POLA2 RNA is bound by 16 proteins.

CanvasJS.com

eCLIP assay for POLA2 is not avaliable on ENCORE database.

16 proteins are bound to POLA2 RNA:

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Search:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr11	65062122	65062156	+	3'-UTR,CDS,intron-Proximal	6.18021	28.25500	K562	AQR
chr11	65062156	65062178	+	intron-Proximal	6.16721	27.71304	K562	AQR
chr11	65071908	65071992	+	intron-Distal	6.89944	25.93951	K562	AGGF1
chr11	65071635	65071748	+	intron-Distal	6.30742	16.62195	K562	AGGF1
chr11	65072113	65072223	+	intron-Distal	5.74355	12.11710	K562	GTF2F1
chr11	65046140	65046225	+	5'-UTR,CDS,intron-Proximal	4.10938	11.37858	K562	SF3B4
chr11	65048436	65048509	+	3'-UTR,CDS,intron-Proximal	4.27892	10.72926	K562	BUD13
chr11	65047114	65047175	+	intron-Proximal	4.76838	10.08262	K562	AQR
chr11	65047137	65047266	+	intron-Distal,intron-Proximal	3.70443	9.49597	K562	PRPF8
chr11	65048408	65048497	+	3'-UTR,CDS,intron-Proximal	3.67957	8.47924	K562	SF3B4
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

Showing 1 to 10 of 42 entries

eCLIP assay for POLA2 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for POLA2 is not available on ENCORE database.
107 RBPs can affect the levels of POLA2.

CanvasJS.com

The Knockdown/knockout RNA-Seq assay for POLA2 is not available on ENCORE database.

107 RBPs can affect the gene expression of POLA2 :

Show entries

Search:

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
POLA2	ENSG00000014138.4	91.27610	431.69450	-2.24170	33.57450	31.79550	HepG2	RPLP0
POLA2	ENSG00000014138.4	183.32690	553.02150	-1.59290	29.49790	28.31150	HepG2	SRFBP1
POLA2	ENSG00000014138.4	156.35450	489.62940	-1.64690	25.08640	23.84110	HepG2	RBM22
POLA2	ENSG00000014138.4	118.82960	373.92260	-1.65380	23.81210	22.60140	HepG2	ZNF622
POLA2	ENSG00000014138.4	129.91830	381.51970	-1.55420	23.74310	22.22600	HepG2	CKAP4
POLA2	ENSG00000014138.4	137.66500	393.67900	-1.51590	21.76100	20.15690	HepG2	SRSF7
POLA2	ENSG00000014138.4	1010.52200	2138.37950	-1.08140	20.99380	19.55040	K562	AQR
POLA2	ENSG00000014138.4	83.72090	354.24830	-2.08110	20.74490	19.20000	HepG2	SUPV3L1
POLA2	ENSG00000014138.4	57.66620	271.58210	-2.23560	19.34300	17.61410	HepG2	RRP9
POLA2	ENSG00000014138.4	273.38670	585.80870	-1.09950	17.17660	15.88720	HepG2	ETF1
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

Showing 1 to 10 of 122 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for POLA2 is not available on ENCORE database.

4 RBPs can affect the splicing of POLA2 :

Show entries

Search:

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	POLA2	ENSG00000014138.4	chr11	+	65062479	65062682	65062016	65062123	65063010	65063070	0.12800	0.00000	0.00000	included	K562	U2AF1
SE	POLA2	ENSG00000014138.4	chr11	+	65062479	65062682	65062016	65062123	65063010	65063070	0.11600	0.00000	0.00000	included	K562	U2AF2
SE	POLA2	ENSG00000014138.4	chr11	+	65047202	65047258	65047008	65047097	65048462	65048618	0.24300	0.00000	0.00004	included	K562	HNRNPK
SE	POLA2	ENSG00000014138.4	chr11	+	65062479	65062682	65062016	65062123	65063010	65063070	0.13900	0.00000	0.00010	included	K562	HNRNPK
SE	POLA2	ENSG00000014138.4	chr11	+	65062479	65062682	65062016	65062123	65063010	65063070	0.27900	0.00240	0.02928	included	HepG2	U2AF2
SE	POLA2	ENSG00000014138.4	chr11	+	65033977	65034177	65029402	65029842	65034947	65035039	-0.05300	0.01270	0.09805	excluded	K562	AQR

Showing 1 to 6 of 6 entries

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

POLA2

General Information

Functions

Localization

Domains (AlphaFold: POLA2)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for POLA2 is not avaliable on ENCORE database.

16 proteins are bound to POLA2 RNA:

eCLIP assay for POLA2 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for POLA2 is not available on ENCORE database.

107 RBPs can affect the gene expression of POLA2 :

The Knockdown/knockout RNA-Seq assay for POLA2 is not available on ENCORE database.

4 RBPs can affect the splicing of POLA2 :

The Knockdown/knockout RNA-Seq assay for POLA2 is not avaliable on ENCORE database.