GDE1

General Information

Gene Name       : GDE1
Gene ID             : ENSG00000006007.11
Essential Gene : No

Functions

Localization

Domains (AlphaFold: GDE1)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878GDE1ENSG00000006007.1119.7017.0118.36ENCSR000AEF
HepG2GDE1ENSG00000006007.1136.7148.4042.55ENCSR985KAT
K562GDE1ENSG00000006007.1123.4623.8523.66ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for GDE1 is not avaliable on ENCORE database.



Proteins bound to RNA
  • GDE1 RNA is bound by 9 proteins.  







eCLIP assay for GDE1 is not avaliable on ENCORE database.





9 proteins are bound to GDE1 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr161951479119514883-3'-UTR,CDS,intron-Distal3.088004.07634HepG2YBX3
chr161951365119513701-3'-UTR,intron-Distal,intron-Proximal5.384189.39648K562PABPC4
chr161951395819514031-3'-UTR,intron-Distal3.654936.40324K562UPF1
chr161951391319513958-3'-UTR,intron-Distal4.706345.24231K562UPF1
chr161951350719513643-3'-UTR,intron-Distal,intron-Proximal4.5605812.28420K562YBX3
chr161951320619513346-3'-UTR,intron-Distal3.367184.51160HepG2UPF1
chr161951901119519096-3'-UTR,CDS,intron-Distal4.4830219.24617K562PUM2
chr161951424519514300-3'-UTR,intron-Distal3.650066.36657K562YBX3
chr161951345219513501-3'-UTR,intron-Distal3.510183.95400K562UPF1
chr161951306619513124-3'-UTR,intron-Distal4.067314.34615K562LIN28B
chr161951468219514757-3'-UTR,intron-Distal4.206403.95192HepG2UPF1
chr161951374919513793-3'-UTR,intron-Distal4.065523.67607K562YBX3
chr161951315719513287-3'-UTR,intron-Distal3.142914.10022HepG2IGF2BP1
chr161953323419533293-5'-UTR,CDS,intron-Distal3.818973.70637K562DDX3X
chr161953336219533415-5'-UTR,intron-Distal5.2479723.17024HepG2DDX3X
chr161953320819533362-5'-UTR,CDS,intron-Distal5.62479400.00000HepG2DDX3X
chr161953328219533362-5'-UTR,CDS,intron-Distal3.8372610.85260HepG2RPS3
chr161953329319533381-5'-UTR,intron-Distal3.946484.08283K562DDX3X
chr161952411819524198-intron-Distal4.104533.73283HepG2HNRNPL
chr161952424019524356-intron-Distal3.678323.51804HepG2HNRNPL
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for GDE1 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for GDE1 is not available on ENCORE database.

  • 119 RBPs can affect the levels of GDE1.  








The Knockdown/knockout RNA-Seq assay for GDE1 is not available on ENCORE database.





119 RBPs can affect the gene expression of GDE1 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
GDE1ENSG00000006007.71761.507201302.487800.435404.316903.00490HepG2AATF
GDE1ENSG00000006007.72234.493801662.480500.426508.742007.78530HepG2ACO1
GDE1ENSG00000006007.71223.933701595.49160-0.382503.072402.02510HepG2ADAR
GDE1ENSG00000006007.73796.061002307.180900.718308.766307.02190HepG2AKAP8
GDE1ENSG00000006007.72392.095601670.283600.5181011.174509.76690HepG2AKAP8L
GDE1ENSG00000006007.74829.480702414.412301.0001018.8588017.03140HepG2ASCC1
GDE1ENSG00000006007.74503.727802476.413600.8628035.9924034.01850HepG2AUH
GDE1ENSG00000006007.71947.213701519.841200.357402.165301.34000HepG2BCCIP
GDE1ENSG00000006007.72238.652001320.589400.761309.135707.63050HepG2BCLAF1
GDE1ENSG00000006007.72635.050402120.198500.313502.725702.13150HepG2BOP1
GDE1ENSG00000006007.71959.896301470.394800.414504.421802.88580HepG2BUD13
GDE1ENSG00000006007.72737.867401973.190100.472407.030805.87380HepG2CALR
GDE1ENSG00000006007.73845.079602940.188800.387002.503401.58220HepG2CCAR1
GDE1ENSG00000006007.72002.521001662.110000.268704.036203.26230HepG2CKAP4
GDE1ENSG00000006007.71420.700501946.50460-0.454304.296203.45710HepG2CPSF6
GDE1ENSG00000006007.71951.165401333.350100.549203.969402.23410HepG2CSTF2T
GDE1ENSG00000006007.73530.348402135.068800.7254022.1028020.64360HepG2CELF1
GDE1ENSG00000006007.71655.864902295.57110-0.4713011.125309.79480HepG2DAZAP1
GDE1ENSG00000006007.7990.225501537.55200-0.6348015.5534013.93280HepG2DDX19B
GDE1ENSG00000006007.71965.926701638.458800.262802.731901.57960HepG2DDX1
GDE1ENSG00000006007.72526.698601437.616400.8135014.5843013.16980HepG2DDX21
GDE1ENSG00000006007.75354.171402795.293000.9376016.3534014.96390HepG2DDX3X
GDE1ENSG00000006007.74501.001003500.142600.362703.656902.17300HepG2DDX47
GDE1ENSG00000006007.71990.531301494.337100.413502.809202.03070HepG2DDX55
GDE1ENSG00000006007.73672.440602210.383500.732304.781403.50840HepG2DDX59
GDE1ENSG00000006007.72097.259501323.430200.664105.943104.32770HepG2AGO1
GDE1ENSG00000006007.71621.031301185.601100.451204.057402.97690HepG2EIF3D
GDE1ENSG00000006007.71877.078102551.13940-0.442703.339002.63800HepG2EIF4A3
GDE1ENSG00000006007.73756.412602843.184100.401708.183207.24320HepG2ETF1
GDE1ENSG00000006007.73709.087701981.681300.9042013.3999011.89830HepG2FIP1L1
GDE1ENSG00000006007.71805.029301243.791400.537204.659803.04780HepG2FKBP4
GDE1ENSG00000006007.71393.735601713.82680-0.298302.428801.69140HepG2FUBP3
GDE1ENSG00000006007.73558.921501750.375301.0237011.980609.88920HepG2FUS
GDE1ENSG00000006007.73449.183502387.590100.530605.260404.35610HepG2G3BP1
GDE1ENSG00000006007.71868.244302534.44950-0.440004.040002.95600HepG2G3BP2
GDE1ENSG00000006007.71398.883101055.620600.406102.933002.00800HepG2GEMIN5
GDE1ENSG00000006007.71965.641101553.833000.339102.604001.61860HepG2GNB2L1
GDE1ENSG00000006007.72028.457301587.187400.353805.512904.18380HepG2HDGF
GDE1ENSG00000006007.71005.052401622.01120-0.690509.748408.64500HepG2HNRNPA1
GDE1ENSG00000006007.72899.040202109.769000.458409.607708.06380HepG2HNRNPA2B1
GDE1ENSG00000006007.72976.781302214.558900.426602.940601.49390HepG2HNRNPAB
GDE1ENSG00000006007.71880.650602249.43480-0.258303.137302.37740HepG2HNRNPF
GDE1ENSG00000006007.71950.787502417.14490-0.309202.425001.76920HepG2HNRNPK
GDE1ENSG00000006007.71736.215802091.04340-0.268304.023503.22270HepG2HNRNPL
GDE1ENSG00000006007.72728.097401792.233200.6060016.7234015.32860HepG2HNRNPU
GDE1ENSG00000006007.71719.183402215.05710-0.365604.130403.26030HepG2IGF2BP1
GDE1ENSG00000006007.72163.152601830.711700.240603.492302.67660HepG2ILF2
GDE1ENSG00000006007.73910.561202510.307800.639405.652103.85410HepG2KRR1
GDE1ENSG00000006007.74342.482403104.556400.484003.718902.75580HepG2LARP4
GDE1ENSG00000006007.71937.040002574.47700-0.410403.306202.59000HepG2MAGOH
GDE1ENSG00000006007.72079.101302588.95310-0.316401.973001.43570HepG2MATR3
GDE1ENSG00000006007.72295.608101240.829000.887504.707703.35660HepG2METAP2
GDE1ENSG00000006007.74118.310301603.875601.3604046.1656043.59300HepG2MSI2
GDE1ENSG00000006007.71882.083101346.772600.482705.679103.94910HepG2NAA15
GDE1ENSG00000006007.71412.851501867.12640-0.402203.370202.54470HepG2NSUN2
GDE1ENSG00000006007.71495.697202451.24010-0.712704.633003.46360HepG2PABPC1
GDE1ENSG00000006007.71724.358102360.24120-0.452903.847703.00760HepG2PABPC4
GDE1ENSG00000006007.72836.496401774.039600.6770019.2828017.43180HepG2PARN
GDE1ENSG00000006007.71640.815102439.93860-0.572405.073802.63330HepG2PPIG
GDE1ENSG00000006007.71616.326101152.668500.487604.148703.18250HepG2PRPF8
GDE1ENSG00000006007.74044.341502378.782900.7656026.9230025.55930HepG2PTBP1
GDE1ENSG00000006007.72584.323002172.961800.250002.117301.58600HepG2PUF60
GDE1ENSG00000006007.72590.390602306.744100.167202.423201.86090HepG2PUM1
GDE1ENSG00000006007.72780.193602305.028600.270302.906602.22010HepG2PUM2
GDE1ENSG00000006007.73112.932801693.342900.8783034.6686032.94410HepG2PUS1
GDE1ENSG00000006007.75803.160002576.438101.1714048.9666046.97120HepG2QKI
GDE1ENSG00000006007.72914.074401599.034800.865706.610105.54520HepG2RAVER1
GDE1ENSG00000006007.73062.917602309.502200.407205.337204.19290HepG2RBM15
GDE1ENSG00000006007.72989.584002376.390400.331104.752504.11980HepG2RBM22
GDE1ENSG00000006007.71073.381601490.63650-0.473803.542202.34150HepG2RCC2
GDE1ENSG00000006007.72326.563402647.41840-0.186402.113501.62800HepG2NELFE
GDE1ENSG00000006007.71924.534002465.59910-0.357406.111005.24420HepG2RECQL
GDE1ENSG00000006007.71860.251801153.659800.6892011.043409.91310HepG2RPS19
GDE1ENSG00000006007.72316.134001692.961100.452104.401703.40470HepG2RPS2
GDE1ENSG00000006007.71756.648202693.03440-0.616405.061503.98070HepG2RPS3A
GDE1ENSG00000006007.71513.837201140.218700.408802.733301.95060HepG2RRP9
GDE1ENSG00000006007.71154.072701596.07970-0.467808.829207.77720HepG2SAFB2
GDE1ENSG00000006007.71670.142701157.849300.528405.302904.01130HepG2SERBP1
GDE1ENSG00000006007.71621.515702319.26540-0.516303.075802.25130HepG2SNRNP70
GDE1ENSG00000006007.71750.957402684.07130-0.6163017.8454016.86620HepG2SRFBP1
GDE1ENSG00000006007.7852.352701423.24830-0.739708.134805.59750HepG2SRP68
GDE1ENSG00000006007.72588.450802145.542300.270603.882303.16260HepG2SRSF5
GDE1ENSG00000006007.73078.598102342.653900.394002.507601.46850HepG2STIP1
GDE1ENSG00000006007.73926.634002440.022100.6863028.2666026.62430HepG2SUCLG1
GDE1ENSG00000006007.74528.997502052.190401.1419028.9645027.09370HepG2TARDBP
GDE1ENSG00000006007.71550.81670997.045000.637206.005104.62900HepG2TFIP11
GDE1ENSG00000006007.73260.189702135.115300.6105010.849809.22710HepG2TIA1
GDE1ENSG00000006007.71389.853501741.59620-0.325503.362902.82130HepG2TIAL1
GDE1ENSG00000006007.72774.865701757.050200.6592019.3207018.00200HepG2TRIM56
GDE1ENSG00000006007.72587.063002122.972100.285102.826101.94440HepG2TUFM
GDE1ENSG00000006007.72836.530301695.218000.7426011.271909.98130HepG2U2AF1
GDE1ENSG00000006007.73647.669602049.422300.831702.447201.52600HepG2U2AF2
GDE1ENSG00000006007.74214.831801677.608501.3290086.7274084.09020HepG2UPF1
GDE1ENSG00000006007.72656.218701724.370100.6232015.3435013.16500HepG2UTP18
GDE1ENSG00000006007.72716.525001619.669800.7460024.6797023.16180HepG2UTP3
GDE1ENSG00000006007.71132.321501464.34330-0.371002.698601.98300HepG2XRN2
GDE1ENSG00000006007.72239.435001569.784700.5125013.1266011.84240HepG2ZC3H8
GDE1ENSG00000006007.72648.051601888.514600.4876010.869309.83770K562AGGF1
GDE1ENSG00000006007.72973.117802075.238200.518606.942405.21540K562AKAP8
GDE1ENSG00000006007.72673.061701965.096400.443805.221004.31120K562AKAP8L
GDE1ENSG00000006007.72743.280202061.880600.411804.383103.20520K562ATP5C1
GDE1ENSG00000006007.71325.628401081.749200.293203.373202.30820K562BCLAF1
GDE1ENSG00000006007.74030.358602934.467800.457706.932205.40800K562CELF1
GDE1ENSG00000006007.73043.970302025.306500.5877015.3073013.88740K562DDX47
GDE1ENSG00000006007.71028.528901409.17640-0.454304.515803.46720K562EIF4A3
GDE1ENSG00000006007.71262.326801011.189600.319902.626401.39570K562EXOSC5
GDE1ENSG00000006007.71792.106301466.676800.289002.088001.34010K562FMR1
GDE1ENSG00000006007.71344.85590941.269200.514706.517604.34110K562FUS
GDE1ENSG00000006007.7988.384001465.48040-0.568209.548508.50550K562FXR1
GDE1ENSG00000006007.71203.82050907.788600.407102.863501.41250K562GEMIN5
GDE1ENSG00000006007.71071.812701359.50510-0.343003.714402.40250K562GLRX3
GDE1ENSG00000006007.71782.294401376.214000.372903.395502.51860K562GPKOW
GDE1ENSG00000006007.71565.723201192.122000.393203.908003.21350K562HNRNPC
GDE1ENSG00000006007.71539.428601949.93460-0.341002.888102.07590K562HSPD1
GDE1ENSG00000006007.73000.902202085.418600.525007.586506.05280K562KIF1C
GDE1ENSG00000006007.72064.594301175.154700.812908.383706.65720K562KRR1
GDE1ENSG00000006007.71004.270601525.24550-0.602908.112006.63600K562MAGOH
GDE1ENSG00000006007.72639.168301996.291100.402703.858802.52090K562MAK16
GDE1ENSG00000006007.71630.683501343.344800.279502.188701.40870K562METAP2
GDE1ENSG00000006007.73214.391302543.454200.337702.938201.76910K562MSI2
GDE1ENSG00000006007.72524.814201637.511300.624605.528304.12830K562NAA15
GDE1ENSG00000006007.71281.66840892.387100.522204.388802.65200K562NONO
GDE1ENSG00000006007.71918.961801588.204400.272803.642402.79900K562NSUN2
GDE1ENSG00000006007.71312.68030949.948700.466503.467001.30830K562PA2G4
GDE1ENSG00000006007.72177.255701414.140600.622502.538101.60100K562PABPN1
GDE1ENSG00000006007.71016.709501357.18780-0.416703.801702.65610K562PCBP2
GDE1ENSG00000006007.7882.459801481.83180-0.7478012.1670010.82460K562PTBP1
GDE1ENSG00000006007.72332.972101948.755400.259501.956701.48520K562PUS1
GDE1ENSG00000006007.72920.836101898.835700.6212013.5842012.26540K562RBM15
GDE1ENSG00000006007.71158.628001421.19000-0.294702.126901.39420K562RBM22
GDE1ENSG00000006007.71332.03270897.449300.569604.701903.63470K562RPS19
GDE1ENSG00000006007.71258.20280900.832300.481902.932101.56460K562RRP9
GDE1ENSG00000006007.71151.412501452.62950-0.335302.997502.26440K562SRSF1
GDE1ENSG00000006007.73000.737401776.384200.756303.316301.70650K562SUPT6H
GDE1ENSG00000006007.71151.39950852.993100.432702.983001.92580K562SUPV3L1
GDE1ENSG00000006007.72448.868801759.627400.476709.341106.98670K562TROVE2
GDE1ENSG00000006007.72117.333101444.528600.551508.790807.34930K562U2AF2
GDE1ENSG00000006007.71183.20380902.846300.390002.805601.77850K562UCHL5
GDE1ENSG00000006007.72113.292701683.999300.327503.174102.40700K562UPF1
GDE1ENSG00000006007.72779.721302169.963700.357203.811602.28640K562WRN
GDE1ENSG00000006007.72999.291801747.672200.779103.577501.67010K562YTHDC2
GDE1ENSG00000006007.73203.871802062.588200.6353010.100608.33920K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for GDE1 is not available on ENCORE database.





5 RBPs can affect the splicing of GDE1 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEGDE1ENSG00000006007.7chr16-195162021951641419513014195149391951900819519101-0.080000.000030.00118excludedK562SRSF1
SEGDE1ENSG00000006007.7chr16-195190081951910119516202195164141952216019522266-0.120000.000030.00110excludedHepG2U2AF1
SEGDE1ENSG00000006007.7chr16-195190081951910119516202195164141952216019522266-0.111000.000000.00000excludedHepG2U2AF2
SEGDE1ENSG00000006007.7chr16-195189761951910119515182195164141952216019522266-0.116000.004790.07872excludedK562U2AF1
SEGDE1ENSG00000006007.7chr16-195190081951910119516202195164141952216019522266-0.090000.000020.00079excludedK562U2AF2
A3SSGDE1ENSG00000006007.7chr16-1952833519528536195283351952851119533025195334670.107000.000040.00034longerK562AQR
MXEGDE1ENSG00000006007.7chr16-1951620219516414195190081951910119513014195149391952216019522266-0.138000.001350.040272includedHepG2XRN2

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for GDE1 is not avaliable on ENCORE database.