YTHDC2

General Information

Gene Name       : YTHDC2
Gene ID             : ENSG00000047188.15
Essential Gene : No

Functions

Localization(RBPImage: YTHDC2)

Domains (AlphaFold: YTHDC2)


Antibody Validation

 View validation images for all YTHDC2 antibodies

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878YTHDC2ENSG00000047188.1518.6616.5717.62ENCSR000AEF
HepG2YTHDC2ENSG00000047188.159.0212.4810.75ENCSR985KAT
K562YTHDC2ENSG00000047188.1510.9710.6810.82ENCSR000AEO

Assays

2 Released experiments are available on ENCORE database.

Assay TypeExp_NameENCODE IDTarget labelBiosampleStatusLinked AntibodyControlsMethodNote
knockdown followed by RNA-seq YTHDC2-BGKLV28-K562ENCSR843LYFYTHDC2K562ReleasedENCSR164MUK   shRNAKD% = 60.1,51.8
knockdown followed by RNA-seq YTHDC2-BGHLV37-HepG2ENCSR289HOVYTHDC2HepG2ReleasedENCSR225PRV   shRNAKD% = 79.6,83.7






  eCLIP  

No eCLIP experiment available



  Antibody Validation  
  GeneName    Antibody_DCC_ID    Product_ID    Lot_ID    Phosphate    HepG2 Primary Validation    K562 Primary Validation    HepG2 Secondary Validation    K562 Secondary Validation  
YTHDC2ENCAB501IJSA303-025A1BGHLV37-105, Released, ENCODE3BGKLV28-63, Released, ENCODE3
YTHDC246324S1Submitted, ENCORE2BGHLV37-105, Submitted, ENCORE2


  KD RNA-Seq  
  GeneName    Cell_Line    Method    Exp_ID    Control_ID    Sample_reps    Control_reps    KD%    Status    Project    Note  
YTHDC2K562shRNABGKLV24-63,BGKLV24-64BGKLV24-1,BGKLV24-2redo transduction,redo transductionNotSatisfiedENCODE3
YTHDC2K562shRNAENCSR843LYFENCSR164MUKYTHDC2_BGKLV28-63,YTHDC2_BGKLV28-64non-target_BGKLV28-1,non-target_BGKLV28-260.1,51.8ReleasedENCODE3
YTHDC2HepG2shRNABGHLV22-59,BGHLV22-60BGHLV22-1,BGHLV22-227.0,48.7NotSatisfiedENCODE3
YTHDC2HepG2shRNAENCSR289HOVENCSR225PRVYTHDC2-BGHLV37-105C,YTHDC2-BGHLV37-106Cnon-target-BGHLV37-1C,non-target-BGHLV37-2C79.6,83.7ReleasedENCODE4
YTHDC2HepG2shRNABGHLV37-107,BGHLV37-108BGHLV37-1,BGHLV37-259.9,62.2NotSatisfiedENCODE3
YTHDC2HepG2shRNABGHLV37-109,BGHLV37-110BGHLV37-1,BGHLV37-265.4,59.6NotSatisfiedENCODE3


  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  
    YTHDC2: Click to RBP Image Database
  • Nuclei
  • Nucleoplasm
  • Mutually Exclusive from Nucleolus
  • Cytoplasm
  • Compartment/Organelle
  • Mitochondria












    • RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela
    YTHDC2Product_ID: 46324S
    Lot_ID: 1
    Source: Cell Signaling Technology
    Target Name: YTHDC2-human    		 YTHDC2-HEPG2-CRISPR-46324S.png<br>Caption: Western blot following shRNA against YTHDC2 in HepG2 whole cell lysate using YTHDC2 specific antibody. Lane 1 is a ladder, lane 2 is HepG2 non-targeting control knockdown, lane 3 and 4 are two different shRNA against YTHDC2. YTHDC2 protein appears as the green arrow, Beta-actin serves as a control and appears in red arrow.
    		 CST_46324S_1_YTHDC2.png<br>Caption: IP-WB analysis of 46324S whole cell lysate using the YTHDC2 specific antibody, 46324S. Lanes 1 and 2 are 2.5% of five million whole cell lysate input and 50% of IP enrichment, respectively, using a normal IgG antibody. Lane 3 is 50% of IP enrichment from five million whole cell lysate using the YTHDC2-specific antibody, 46324S. The same antibody was used to detect protein levels via Western blot. This antibody passes preliminary validation and will be further pursued for secondary validation. *NOTE* Protein sizes are taken from Genecards.org and are only estimates based on sequence. Actual protein size may differ based on protein characteristics and electrophoresis method used.
    YTHDC2Product_ID: A303-025A
    Lot_ID: 1
    Source: Bethyl Labs
    Target Name: YTHDC2-human    		 YTHDC2-HEPG2.png<br>Caption: Western blot following shRNA against YTHDC2 in HepG2 whole cell lysate using YTHDC2 specific antibody. Lane 1 is a ladder, lane 2 is HepG2 non-targeting control knockdown, lane 3 and 4 are two different shRNAs against YTHDC2. YTHDC2 protein appears as the green band, Tubulin serves as a control and appears in red.
    		 YTHDC2-k562_Secondary_Western.png<br>Caption: Western blot following shRNA against YTHDC2 in K562 whole cell lysate using YTHDC2 specific antibody. Lane 1 is a ladder, lane 2 is K562 non-targeting control knockdown, lane 3 and 4 are two different shRNAs against YTHDC2.YTHDC2 protein appears as the green band, Tubulin serves as a control and appears in red.








    RNA Targets

    • eCLIP assay for YTHDC2 is not avaliable on ENCORE database.



    Proteins bound to RNA
    • YTHDC2 RNA is bound by 18 proteins.  







    eCLIP assay for YTHDC2 is not avaliable on ENCORE database.





    18 proteins are bound to YTHDC2 RNA:

    Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
    chr5112889396112889488+3'-UTR,CDS,intron-Proximal4.131423.31283K562PRPF8
    chr5112930611112930684+3'-UTR3.447835.12038K562PUM2
    chr5112889021112889058+3'-UTR,CDS,intron-Proximal3.877104.51739HepG2BCLAF1
    chr5112888922112888971+3'-UTR,CDS4.288667.16838HepG2BCLAF1
    chr5112929862112929930+3'-UTR6.1006158.55982HepG2PCBP2
    chr5112889288112889370+3'-UTR,CDS4.017577.65975HepG2BCLAF1
    chr5112876664112876733+3'-UTR,CDS,intron-Proximal3.117363.12941K562UCHL5
    chr5112874811112874880+3'-UTR,CDS,intron-Proximal5.8728213.58086HepG2BCLAF1
    chr5112929874112930006+3'-UTR3.6149812.61044K562ILF3
    chr5112876759112876812+3'-UTR,CDS3.485655.56491HepG2BCLAF1
    chr5112929159112929227+3'-UTR,intron-Proximal3.6741114.57527HepG2U2AF2
    chr5112884237112884327+3'-UTR,CDS,intron-Proximal4.315897.49468HepG2BCLAF1
    chr5112876664112876739+3'-UTR,CDS,intron-Proximal5.0268812.89578HepG2BCLAF1
    chr5112878062112878109+3'-UTR,CDS,intron-Proximal4.955875.23259HepG2BCLAF1
    chr5112889449112889508+3'-UTR,CDS,intron-Proximal4.393064.19412K562EFTUD2
    chr5112930731112930770+3'-UTR4.135033.34480K562PUM2
    chr5112891787112891833+3'-UTR,CDS,intron-Proximal3.526883.94979HepG2BCLAF1
    chr5112930854112930940+3'-UTR3.827013.22073HepG2KHSRP
    chr5112929930112929990+3'-UTR6.8854478.77825HepG2PCBP2
    chr5112888877112888963+3'-UTR,CDS,intron-Proximal4.475844.55944K562ZNF622
    chr5112870054112870092+5'-UTR,CDS3.668163.68471HepG2BCLAF1
    chr5112868624112868728+5'-UTR,CDS4.102889.37631HepG2BCLAF1
    chr5112871382112871425+5'-UTR,CDS3.533783.27569HepG2BCLAF1
    chr5112899610112899701+CDS4.905958.49499K562KHSRP
    chr5112926908112926980+CDS,intron-Proximal5.066476.35567HepG2PRPF8
    chr5112899069112899092+CDS,intron-Proximal4.469144.70478HepG2BCLAF1
    chr5112899775112899857+CDS,intron-Proximal4.780034.35676HepG2PRPF8
    chr5112899579112899679+CDS3.130117.97025HepG2BCLAF1
    chr5112903349112903395+CDS,intron-Proximal3.613905.15500HepG2BCLAF1
    chr5112920148112920180+CDS,intron-Proximal3.130114.61799HepG2BCLAF1
    chr5112926913112926972+CDS,intron-Proximal4.073683.02181K562PRPF8
    chr5112928959112929031+CDS,intron-Proximal4.683769.99997HepG2U2AF2
    chr5112926737112926757+CDS,intron-Proximal4.091524.51739HepG2BCLAF1
    chr5112927659112927750+CDS,intron-Proximal3.908865.18845HepG2U2AF2
    chr5112927816112927841+CDS3.422593.57857HepG2BCLAF1
    chr5112927692112927733+CDS,intron-Proximal3.441925.15500HepG2BCLAF1
    chr5112873249112873336+intron-Distal4.040863.09122HepG2PTBP1
    chr5112878342112878526+intron-Distal3.355034.08064K562KHSRP
    chr5112866268112866365+intron-Distal3.903143.14791K562HNRNPL
    chr5112908764112908834+intron-Distal4.378483.98115K562MATR3
    chr5112907665112907741+intron-Distal4.174443.62238HepG2MATR3
    chr5112909819112909889+intron-Distal3.886245.20902K562EXOSC5
    chr5112908754112908837+intron-Distal3.809023.16028HepG2SUGP2
    chr5112916274112916361+intron-Distal4.379015.18391K562HNRNPL
    chr5112873250112873321+intron-Distal4.232123.42734K562PTBP1
    chr5112908722112908829+intron-Distal5.7257211.99379K562EXOSC5
    chr5112907675112907728+intron-Distal4.233817.61413K562EXOSC5
    chr5112900070112900151+intron-Distal4.937816.73684K562KHSRP
    chr5112928129112928243+intron-Distal3.289057.68575K562KHSRP
    chr5112927982112928095+intron-Distal3.544635.38829K562KHSRP
    chr5112913503112913658+intron-Distal3.742499.70788K562KHSRP
    chr5112879137112879213+intron-Distal4.506996.10900HepG2HNRNPL
    chr5112916271112916380+intron-Distal3.875477.66770HepG2HNRNPL
    chr5112893346112893495+intron-Distal3.141344.32871K562AKAP8L
    chr5112896479112896578+intron-Distal4.374364.31512K562KHSRP
    chr5112907022112907065+intron-Distal3.348554.02190K562EXOSC5
    chr5112900020112900070+intron-Distal3.021323.28806K562KHSRP
    chr5112921972112922118+intron-Distal3.803356.89441K562KHSRP
    chr5112907135112907192+intron-Distal5.261807.38693K562EXOSC5
    chr5112899945112900007+intron-Distal3.019114.76345K562KHSRP
    chr5112905511112905601+intron-Distal4.566609.10500K562EXOSC5
    chr5112908575112908635+intron-Distal4.900326.73640K562EXOSC5
    chr5112903647112903713+intron-Distal4.276054.54401K562KHSRP
    chr5112909862112909947+intron-Distal3.729534.61322HepG2MATR3
    chr5112926556112926688+intron-Distal,intron-Proximal4.151064.54401K562KHSRP
    chr5112907485112907534+intron-Distal4.380703.28572K562HNRNPM
    chr5112921641112921697+intron-Distal3.095253.06005HepG2QKI
    chr5112907974112908033+intron-Distal5.083027.38693K562EXOSC5
    chr5112907740112907779+intron-Distal4.126756.41110K562EXOSC5
    chr5112920995112921106+intron-Distal4.743015.44709K562KHSRP
    chr5112903719112903812+intron-Distal4.772827.17304K562KHSRP
    chr5112908733112908806+intron-Distal4.425694.87593HepG2MATR3
    chr5112905246112905287+intron-Distal4.007023.01445K562EXOSC5
    chr5112905214112905246+intron-Distal3.214543.43875K562EXOSC5
    chr5112909291112909321+intron-Distal3.431024.31658K562EXOSC5
    chr5112907241112907313+intron-Distal4.951866.73731K562EXOSC5
    chr5112863808112863928+intron-Distal4.170304.54401K562KHSRP
    chr5112912465112912539+intron-Distal5.192118.27925K562KHSRP
    chr5112892220112892283+intron-Distal4.953844.99795K562QKI
    chr5112912539112912584+intron-Distal3.968515.95946K562KHSRP
    chr5112913732112913795+intron-Distal3.042233.29251K562KHSRP
    ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




    eCLIP assay for YTHDC2 is not avaliable on ENCORE database.



    Diffrential Expression
    • 549 differentially expressed genes after Knockdown/Knockout YTHDC2 protein.  





    • 101 RBPs can affect the levels of YTHDC2.  







    549 differentially expressed genes after Knockdown/Knockout YTHDC2 protein :

    Only display 100 entries as example. Please click "View All" button to see all 549 entries.     

    Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
    GCLCENSG00000001084.6948.86400537.049600.821003.475401.62870K562YTHDC2
    FAM214BENSG00000005238.15388.91950202.329800.942703.531901.65230K562YTHDC2
    GDE1ENSG00000006007.72999.291801747.672200.779103.577501.67010K562YTHDC2
    JHDM1DENSG00000006459.62680.104501668.360000.683803.068201.37920K562YTHDC2
    TKTL1ENSG00000007350.1291.8754028.957501.665603.858601.85070K562YTHDC2
    PAX6ENSG00000007372.16454.07240232.930100.962903.949101.89290K562YTHDC2
    RPUSD1ENSG00000007376.343.85110167.46600-1.933207.580704.42660K562YTHDC2
    PIGQENSG00000007541.10132.12310268.01260-1.020403.793501.80700K562YTHDC2
    DNAJC11ENSG00000007923.111412.539203128.97950-1.147403.125201.41180K562YTHDC2
    PIK3C2AENSG00000011405.93866.770601819.026901.087903.631201.70460K562YTHDC2
    ANLNENSG00000011426.64884.404002836.077100.784203.786601.80350K562YTHDC2
    TMEM159ENSG00000011638.6341.98230151.619201.173404.105201.98540K562YTHDC2
    ERP44ENSG00000023318.74268.260102534.823300.751703.425901.60480K562YTHDC2
    EHD2ENSG00000024422.7820.995101348.17760-0.715603.133601.41570K562YTHDC2
    CCDC28AENSG00000024862.12827.39310467.986500.822003.525101.65090K562YTHDC2
    VIMENSG00000026025.912142.038107634.221000.669402.992401.32980K562YTHDC2
    BTN3A1ENSG00000026950.12707.06400361.617300.967304.261602.07850K562YTHDC2
    IFNGR1ENSG00000027697.81148.16770643.208900.835903.021601.34800K562YTHDC2
    SH2D2AENSG00000027869.7379.53200764.39600-1.010105.048102.60080K562YTHDC2
    UHRF1ENSG00000034063.9776.589801478.76400-0.929203.306201.52260K562YTHDC2
    HSPA5ENSG00000044574.7109146.9242065017.077400.747303.835501.83470K562YTHDC2
    YTHDC2ENSG00000047188.111394.014002428.57230-0.800903.928701.88840K562YTHDC2
    FAM214AENSG00000047346.8468.23380245.259400.932803.760401.79400K562YTHDC2
    HEXBENSG00000049860.93081.815901740.829700.823904.048701.95420K562YTHDC2
    MRTO4ENSG00000053372.4879.476701596.70290-0.860403.641701.71360K562YTHDC2
    KMT2CENSG00000055609.1311322.997305905.064100.939104.051001.95420K562YTHDC2
    ZNF280CENSG00000056277.11675.78700368.687300.874103.593701.68050K562YTHDC2
    SEC61A1ENSG00000058262.56528.741903970.654700.717303.189901.44680K562YTHDC2
    CDK17ENSG00000059758.31401.85190850.888700.720202.993101.32980K562YTHDC2
    DNAJC25ENSG00000059769.151295.95600736.690300.814804.041201.95330K562YTHDC2
    NCKAP1ENSG00000061676.107974.389504773.306100.740303.544601.65560K562YTHDC2
    SPHK2ENSG00000063176.1131.38420115.22530-1.876305.980403.15210K562YTHDC2
    NGFRENSG00000064300.4104.2326025.535202.029105.541302.88110K562YTHDC2
    TMEM161AENSG00000064545.10367.50140682.12920-0.892303.846501.84400K562YTHDC2
    ABCA7ENSG00000064687.81149.241702210.96340-0.944004.546802.28060K562YTHDC2
    HMG20BENSG00000064961.141512.826202426.58500-0.681703.047401.36790K562YTHDC2
    SLC9A3R2ENSG00000065054.9169.95110418.25210-1.299306.419803.45030K562YTHDC2
    WDR18ENSG00000065268.6302.95090746.99500-1.302007.723504.54310K562YTHDC2
    NDUFB4ENSG00000065518.71797.03750898.041901.000703.027501.35140K562YTHDC2
    KLF6ENSG00000067082.102757.802801562.909100.819203.917201.88480K562YTHDC2
    HEATR6ENSG00000068097.101162.16460673.809200.786303.300201.52050K562YTHDC2
    POLR1AENSG00000068654.11927.694101646.17430-0.827404.118601.99180K562YTHDC2
    SIRT2ENSG00000068903.151159.41570687.364000.754203.098601.39560K562YTHDC2
    UFD1LENSG00000070010.1417647.2021010435.003400.757903.206701.45660K562YTHDC2
    LRP6ENSG00000070018.43047.304501917.693500.668103.087301.39030K562YTHDC2
    DGCR2ENSG00000070413.141190.307202419.94150-1.023604.970602.54030K562YTHDC2
    MBD3ENSG00000071655.13197.35300576.38940-1.546303.236701.47850K562YTHDC2
    AFF4ENSG00000072364.84435.500202539.279100.804603.964701.90240K562YTHDC2
    ZNF37AENSG00000075407.13626.645501078.88210-0.783803.442801.61470K562YTHDC2
    SPAG5ENSG00000076382.129545.942405925.044500.688003.096101.39550K562YTHDC2
    FAM76BENSG00000077458.82157.439401336.907800.690302.951701.30600K562YTHDC2
    SIRT6ENSG00000077463.10146.20100288.76540-0.981903.564401.66560K562YTHDC2
    SAR1AENSG00000079332.105491.352703169.723900.792703.864601.85480K562YTHDC2
    PAFAH1B3ENSG00000079462.3307.41140563.84800-0.875103.622401.69880K562YTHDC2
    CNOT4ENSG00000080802.142105.601401195.826900.816103.070901.38070K562YTHDC2
    ARG2ENSG00000081181.35718.390902955.830600.951905.302002.70980K562YTHDC2
    SLC27A5ENSG00000083807.5209.07010428.33370-1.034703.176901.44070K562YTHDC2
    HBQ1ENSG00000086506.266.13280300.60680-2.184404.935602.52840K562YTHDC2
    ERO1LBENSG00000086619.91507.96310768.319400.972705.272402.70740K562YTHDC2
    BAXENSG00000087088.15254.79080518.20480-1.024204.662302.34210K562YTHDC2
    ARHGAP4ENSG00000089820.11506.712601219.94540-1.267602.969401.31810K562YTHDC2
    SUCOENSG00000094975.92212.048301221.828000.856204.164702.01470K562YTHDC2
    BTAF1ENSG00000095564.96898.692704121.978400.742903.541001.65470K562YTHDC2
    SYDE2ENSG00000097096.8492.59540277.041000.830203.187501.44660K562YTHDC2
    ERMP1ENSG00000099219.92527.480801527.239600.726703.366501.56480K562YTHDC2
    RAB18ENSG00000099246.122365.874301331.672600.829004.045801.95350K562YTHDC2
    FBXL19ENSG00000099364.12225.34420503.71160-1.160505.900103.10660K562YTHDC2
    CEP170BENSG00000099814.11138.22070313.75970-1.182703.677101.73660K562YTHDC2
    RASSF7ENSG00000099849.10101.06550219.89210-1.121503.932301.88840K562YTHDC2
    GADD45BENSG00000099860.4139.3143056.786901.294603.299701.52050K562YTHDC2
    ZDHHC8ENSG00000099904.11628.823701089.87100-0.793403.803201.81130K562YTHDC2
    LGALS1ENSG00000100097.71429.41580851.601800.747103.152701.42620K562YTHDC2
    FBXO7ENSG00000100225.135202.107202990.610700.798603.249701.48740K562YTHDC2
    MCATENSG00000100294.855.05330136.68680-1.312003.781401.80170K562YTHDC2
    TTLL12ENSG00000100304.121727.224402935.47170-0.765103.936901.88840K562YTHDC2
    MTMR3ENSG00000100330.111812.351401105.030900.713703.133501.41570K562YTHDC2
    TNRC6BENSG00000100354.161877.578801093.313100.780103.527101.65090K562YTHDC2
    POLR3HENSG00000100413.12118.02560256.86020-1.121904.065801.95780K562YTHDC2
    PIGHENSG00000100564.4434.27440228.573700.925803.086801.39030K562YTHDC2
    CCNB1IP1ENSG00000100814.132813.807301389.773101.017605.779303.03830K562YTHDC2
    SEC23AENSG00000100934.102455.885101428.664500.781503.784301.80290K562YTHDC2
    PROCRENSG00000101000.490.4068031.019801.543103.556401.66180K562YTHDC2
    TUBB1ENSG00000101162.3189.18850344.90310-0.866403.116601.40600K562YTHDC2
    C20orf27ENSG00000101220.13188.39290363.77250-0.949303.715901.76440K562YTHDC2
    AMMECR1ENSG00000101935.51422.052002357.70690-0.729403.479801.63180K562YTHDC2
    MAGED2ENSG00000102316.122365.674501383.637200.773703.492201.63660K562YTHDC2
    ARMCX3ENSG00000102401.153058.121201940.272200.656303.034301.35650K562YTHDC2
    TNFSF13BENSG00000102524.7107.2376041.695301.362803.178601.44140K562YTHDC2
    KATNAL1ENSG00000102781.9840.82430478.909200.812003.132701.41570K562YTHDC2
    CORO1AENSG00000102879.1179.25950163.28400-1.042702.992001.32980K562YTHDC2
    CAPN15ENSG00000103326.6509.404001018.42780-0.999505.309302.70980K562YTHDC2
    PIEZO1ENSG00000103335.154352.557807396.99470-0.765103.552801.66100K562YTHDC2
    DMXL2ENSG00000104093.97212.878604528.347800.671503.145301.42160K562YTHDC2
    UBE2WENSG00000104343.15505.90630277.215400.867803.571201.66570K562YTHDC2
    POP1ENSG00000104356.6140.68870268.83400-0.934203.130101.41560K562YTHDC2
    UBR5ENSG00000104517.813296.595407806.497900.768203.765601.79400K562YTHDC2
    PYCRLENSG00000104524.928.43410106.49500-1.905105.661002.95770K562YTHDC2
    AMHENSG00000104899.471.08840200.24780-1.494103.422401.60480K562YTHDC2
    LYL1ENSG00000104903.4461.741601160.12670-1.329108.780605.39610K562YTHDC2
    ICAM4ENSG00000105371.8389.77000662.38100-0.765002.999901.33470K562YTHDC2
    Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

    *: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
    **: "-log(0)" was displayed as "99999.99999".





    101 RBPs can affect the gene expression of YTHDC2 :

    Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
    YTHDC2ENSG00000047188.111250.695701002.691500.318803.918303.21850HepG2ACO1
    YTHDC2ENSG00000047188.111379.308901007.419000.453204.561703.59470HepG2AKAP8L
    YTHDC2ENSG00000047188.11682.83690932.39660-0.449403.140902.30340HepG2ASCC1
    YTHDC2ENSG00000047188.111179.373501611.95840-0.450803.569602.89940HepG2BOP1
    YTHDC2ENSG00000047188.111551.859301078.983100.524205.220604.20200HepG2CALR
    YTHDC2ENSG00000047188.111167.204801002.493500.219402.160101.56160HepG2CKAP4
    YTHDC2ENSG00000047188.111176.011701479.90140-0.331602.119601.50900HepG2CPSF6
    YTHDC2ENSG00000047188.111121.613001318.87960-0.233702.762802.02140HepG2DAZAP1
    YTHDC2ENSG00000047188.111401.90660836.414500.7450010.270609.05410HepG2DDX21
    YTHDC2ENSG00000047188.111014.41950817.965400.310402.226701.41800HepG2DDX24
    YTHDC2ENSG00000047188.11631.44920764.67800-0.276202.046901.43160HepG2DNAJC21
    YTHDC2ENSG00000047188.11913.18930693.772400.396402.774901.66430HepG2EFTUD2
    YTHDC2ENSG00000047188.111415.78600985.084600.523204.086503.31350HepG2EIF4A3
    YTHDC2ENSG00000047188.111720.399601209.190800.508604.097403.17550HepG2FIP1L1
    YTHDC2ENSG00000047188.11856.82760551.067800.636706.822105.62090HepG2FUBP3
    YTHDC2ENSG00000047188.111266.81770978.904400.371902.593101.73320HepG2G3BP2
    YTHDC2ENSG00000047188.111205.316001677.68150-0.477103.765803.02820HepG2GPKOW
    YTHDC2ENSG00000047188.11872.779201211.49850-0.473104.503303.61350HepG2HNRNPF
    YTHDC2ENSG00000047188.11503.08140933.73260-0.8922010.862309.55870HepG2HNRNPK
    YTHDC2ENSG00000047188.11890.116701201.43270-0.432707.153306.11500HepG2HNRNPL
    YTHDC2ENSG00000047188.11635.33630853.02040-0.425104.853204.06850HepG2HNRNPU
    YTHDC2ENSG00000047188.11966.385501192.99590-0.303902.193801.54440HepG2IGF2BP1
    YTHDC2ENSG00000047188.111039.31520871.334600.254202.758102.02660HepG2ILF2
    YTHDC2ENSG00000047188.111273.26350994.334600.356602.301501.70160HepG2MAGOH
    YTHDC2ENSG00000047188.111478.443201023.429700.530604.492403.69440HepG2NCBP2
    YTHDC2ENSG00000047188.111046.713801307.79220-0.321303.219802.39940HepG2NOL12
    YTHDC2ENSG00000047188.11521.55060858.04890-0.718303.858802.79770HepG2PABPC1
    YTHDC2ENSG00000047188.111152.21130911.383400.338202.064901.43290HepG2PABPC4
    YTHDC2ENSG00000047188.111500.03920870.642400.7847018.9267017.57080HepG2PCBP1
    YTHDC2ENSG00000047188.111044.28850727.503200.521404.839503.80390HepG2PRPF8
    YTHDC2ENSG00000047188.111060.74350885.912300.259702.186701.68960HepG2PTBP1
    YTHDC2ENSG00000047188.11772.537801248.37070-0.692409.406108.39630HepG2PUF60
    YTHDC2ENSG00000047188.111736.215701325.163900.389707.096006.23580HepG2PUM1
    YTHDC2ENSG00000047188.111077.805701324.21880-0.297002.675602.01610HepG2PUM2
    YTHDC2ENSG00000047188.111710.66740959.462500.8342017.4793016.10330HepG2QKI
    YTHDC2ENSG00000047188.111897.123501598.565500.246902.475701.97840HepG2RBM22
    YTHDC2ENSG00000047188.111190.80740870.774800.451504.472303.63120HepG2RBM25
    YTHDC2ENSG00000047188.111180.24250985.934400.259402.303701.80070HepG2NELFE
    YTHDC2ENSG00000047188.111231.09030918.265600.422905.502604.67010HepG2RECQL
    YTHDC2ENSG00000047188.111194.13500971.745500.297202.011301.32120HepG2RPS2
    YTHDC2ENSG00000047188.11914.17240719.685400.345002.304201.57960HepG2RRP9
    YTHDC2ENSG00000047188.11843.17270659.759400.353802.289701.43120HepG2SERBP1
    YTHDC2ENSG00000047188.111119.90120922.347000.279902.619202.04080HepG2SF3B4
    YTHDC2ENSG00000047188.111166.370401763.30690-0.596303.828702.90340HepG2SNRNP70
    YTHDC2ENSG00000047188.111487.426801805.53090-0.279603.659503.10790HepG2SRFBP1
    YTHDC2ENSG00000047188.112042.47090962.731401.0850039.4113038.08160HepG2SRSF1
    YTHDC2ENSG00000047188.11912.562801190.20270-0.383203.417402.65530HepG2SRSF7
    YTHDC2ENSG00000047188.111417.59250865.342800.7120013.0639011.98140HepG2TAF15
    YTHDC2ENSG00000047188.11582.51590828.92320-0.508904.068603.48720HepG2TIAL1
    YTHDC2ENSG00000047188.111333.05620927.873700.522603.127401.77910HepG2XRCC5
    YTHDC2ENSG00000047188.111061.57990906.102600.228402.072601.47850HepG2ZC3H8
    YTHDC2ENSG00000047188.111643.436801267.811400.374306.711405.95630HepG2ZNF622
    YTHDC2ENSG00000047188.111816.349702461.29310-0.438404.716903.98810K562AQR
    YTHDC2ENSG00000047188.111176.086401441.06930-0.293102.919001.56530K562BCCIP
    YTHDC2ENSG00000047188.111105.086901392.58380-0.333604.175902.98150K562BCLAF1
    YTHDC2ENSG00000047188.111122.352901751.76380-0.642307.303605.86290K562BOP1
    YTHDC2ENSG00000047188.111880.595702370.69800-0.334103.593202.22400K562CCDC124
    YTHDC2ENSG00000047188.111458.660801928.69120-0.403003.846602.32420K562CIRBP
    YTHDC2ENSG00000047188.111539.035302095.86410-0.445502.848901.39110K562CKAP4
    YTHDC2ENSG00000047188.111806.073502517.69320-0.479208.591706.62150K562CPEB4
    YTHDC2ENSG00000047188.111203.239101862.66210-0.630409.395207.93170K562CPSF6
    YTHDC2ENSG00000047188.11830.957301056.48230-0.346403.296302.12710K562CSTF2
    YTHDC2ENSG00000047188.11951.640101344.66200-0.498804.124602.81760K562DDX3X
    YTHDC2ENSG00000047188.111765.826502604.93530-0.5609013.0138011.71020K562DDX47
    YTHDC2ENSG00000047188.111044.154601363.34560-0.384803.463101.95950K562DDX6
    YTHDC2ENSG00000047188.11952.358301221.91090-0.359602.473801.61280K562EFTUD2
    YTHDC2ENSG00000047188.111179.509601477.15070-0.324602.582001.42580K562EIF2S1
    YTHDC2ENSG00000047188.111164.930801690.25460-0.537009.077307.88880K562EIF2S2
    YTHDC2ENSG00000047188.111031.144701288.38840-0.321303.145502.29870K562EIF3G
    YTHDC2ENSG00000047188.111021.908201404.89790-0.459203.017502.16290K562EIF4A3
    YTHDC2ENSG00000047188.11937.951201265.24220-0.431803.875502.46930K562EIF4B
    YTHDC2ENSG00000047188.111483.126401902.90540-0.359603.205202.28980K562FIP1L1
    YTHDC2ENSG00000047188.111172.381001895.14750-0.692907.079505.68410K562FMR1
    YTHDC2ENSG00000047188.111287.088301606.27940-0.319602.206601.39460K562FTO
    YTHDC2ENSG00000047188.111188.049401461.04470-0.298402.291601.73230K562FXR1
    YTHDC2ENSG00000047188.11952.042001778.41160-0.9015013.3787011.61660K562GPKOW
    YTHDC2ENSG00000047188.111351.546502252.59920-0.7370012.2781010.66570K562GRSF1
    YTHDC2ENSG00000047188.111142.880501797.47150-0.653307.567605.43560K562HNRNPK
    YTHDC2ENSG00000047188.111484.375902354.22340-0.6654011.009908.78360K562HNRNPL
    YTHDC2ENSG00000047188.11925.018601565.12090-0.758708.572106.77290K562HNRNPM
    YTHDC2ENSG00000047188.111363.091001867.43070-0.454206.720805.32290K562HNRNPU
    YTHDC2ENSG00000047188.111506.761002580.00030-0.7759012.6898011.02670K562HSPD1
    YTHDC2ENSG00000047188.111288.062001798.92870-0.481903.643502.40370K562IGF2BP2
    YTHDC2ENSG00000047188.111308.561501830.01030-0.483905.427403.65730K562IGF2BP3
    YTHDC2ENSG00000047188.111376.880001891.23690-0.457905.239704.07460K562MAGOH
    YTHDC2ENSG00000047188.111063.351701735.91650-0.7071010.771308.96720K562METAP2
    YTHDC2ENSG00000047188.111341.681001786.70520-0.413306.841505.61730K562MTPAP
    YTHDC2ENSG00000047188.111054.737901402.79580-0.411403.423602.04690K562NCBP2
    YTHDC2ENSG00000047188.11777.179001203.64590-0.631105.983803.92510K562NONO
    YTHDC2ENSG00000047188.111744.154401985.18610-0.186702.442101.73700K562NSUN2
    YTHDC2ENSG00000047188.112063.790402917.02070-0.499202.636601.43830K562PABPC1
    YTHDC2ENSG00000047188.111317.295701682.84820-0.353303.099502.06460K562PCBP2
    YTHDC2ENSG00000047188.111246.618402160.10780-0.7931012.4110010.28160K562PPIG
    YTHDC2ENSG00000047188.11878.986001189.05650-0.435903.313102.49030K562PRPF8
    YTHDC2ENSG00000047188.11874.287901165.26730-0.414503.180402.20130K562PSIP1
    YTHDC2ENSG00000047188.111105.212101837.40770-0.7333013.0781011.69120K562PTBP1
    YTHDC2ENSG00000047188.112030.460803448.97810-0.7644013.1259011.33130K562PUF60
    YTHDC2ENSG00000047188.112610.128803594.42750-0.461609.071207.31270K562PUM2
    YTHDC2ENSG00000047188.111087.025801762.20070-0.697007.946106.42330K562RBM22
    YTHDC2ENSG00000047188.111341.014601717.54460-0.357002.673901.33080K562RBM34
    YTHDC2ENSG00000047188.11712.503201062.98050-0.577106.659205.11950K562RCC2
    YTHDC2ENSG00000047188.111341.016901854.35340-0.467604.452903.03180K562NELFE
    YTHDC2ENSG00000047188.111237.346001607.42970-0.377503.392001.49680K562RECQL
    YTHDC2ENSG00000047188.11828.117201211.28700-0.548604.075403.08270K562RPS19
    YTHDC2ENSG00000047188.11926.105301214.72210-0.391402.694601.70460K562RPS3
    YTHDC2ENSG00000047188.111192.904501958.87770-0.7155016.2257014.37750K562SF3A3
    YTHDC2ENSG00000047188.11937.925501646.05880-0.8115016.0555013.85130K562SF3B4
    YTHDC2ENSG00000047188.111501.520801801.20110-0.262502.120701.49240K562SRSF1
    YTHDC2ENSG00000047188.111289.623901700.92270-0.399403.590202.36360K562SRSF5
    YTHDC2ENSG00000047188.11797.175801151.44090-0.530504.081302.82810K562SUPV3L1
    YTHDC2ENSG00000047188.111042.015201823.08620-0.8070011.054609.48270K562TARDBP
    YTHDC2ENSG00000047188.111189.748601758.53230-0.563707.959506.45890K562TIA1
    YTHDC2ENSG00000047188.11806.017401120.81340-0.475703.642502.56450K562TIAL1
    YTHDC2ENSG00000047188.111332.766501725.28040-0.372403.373602.14460K562TRA2A
    YTHDC2ENSG00000047188.11913.183101190.52420-0.382603.076302.06790K562TRIM56
    YTHDC2ENSG00000047188.111538.108301053.196100.546303.314101.36490K562TRNAU1AP
    YTHDC2ENSG00000047188.111124.930401584.71620-0.494406.473605.25130K562U2AF2
    YTHDC2ENSG00000047188.113188.895703888.74640-0.286202.804001.39280K562UBE2L3
    YTHDC2ENSG00000047188.11912.761901218.56970-0.416903.061701.98520K562UCHL5
    YTHDC2ENSG00000047188.111610.697902104.93520-0.386106.624705.56710K562UPF1
    YTHDC2ENSG00000047188.111410.843502054.09540-0.541903.423602.08300K562UTP3
    YTHDC2ENSG00000047188.111641.811201872.96550-0.190002.113501.36610K562WDR43
    YTHDC2ENSG00000047188.11883.088601240.70470-0.490504.086902.50600K562XRN2
    YTHDC2ENSG00000047188.111394.014002428.57230-0.800903.928701.88840K562YTHDC2
    YTHDC2ENSG00000047188.112032.863802772.65050-0.447805.202203.95780K562ZC3H8
    Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

    *: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
    **: "-log(0)" was displayed as "99999.99999".






    The Knockdown/knockout RNA-Seq assay for YTHDC2 is not available on ENCORE database.





    9 RBPs can affect the splicing of YTHDC2 :

    Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
    SEYTHDC2ENSG00000047188.11chr5+112860677112860874112850968112851059112862282112862482-0.232000.000270.00711excludedK562SRSF1
    SEYTHDC2ENSG00000047188.11chr5+112860677112860874112850968112851059112862282112862400-0.267000.002520.04362excludedK562SF3B4
    SEYTHDC2ENSG00000047188.11chr5+112860677112860874112850968112851059112862282112862400-0.198000.002140.02671excludedHepG2U2AF2
    SEYTHDC2ENSG00000047188.11chr5+112860677112860874112850968112851059112862282112862482-0.171000.000130.00214excludedK562AQR
    SEYTHDC2ENSG00000047188.11chr5+112903350112903546112902788112902878112915282112915363-0.411000.000030.00526excludedK562SUPV3L1
    SEYTHDC2ENSG00000047188.11chr5+112860677112860874112850968112851059112862282112862400-0.146000.005800.09063excludedK562U2AF1
    SEYTHDC2ENSG00000047188.11chr5+112860677112860874112850968112851059112862282112862400-0.177000.002960.09111excludedK562SF3B1
    RIYTHDC2ENSG00000047188.11chr5+112899555112899828112899555112899637112899738112899828-0.093000.000590.00884excludedK562AGGF1
    RIYTHDC2ENSG00000047188.11chr5+112899555112899828112899555112899637112899738112899828-0.081000.002350.02619excludedK562RBM15

    *: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
    **: "-log(0)" was displayed as "99999.99999".





    The Knockdown/knockout RNA-Seq assay for YTHDC2 is not avaliable on ENCORE database.