CDK17

General Information

Gene Name : CDK17
Gene ID : ENSG00000059758.7
Essential Gene : No

Functions

Not Available

Localization

Not Available

Domains (AlphaFold: CDK17)

Not Available

Antibody Validation

Not Avaiable

Expression Level in Cell lines

Cell Line	Gene Name	Ensembl ID	Rep1 TPM	Rep2 TPM	Average TPM	Experiment ID
Gm12878	CDK17	ENSG00000059758.7	32.61	17.17	24.89	ENCSR000AEF
HepG2	CDK17	ENSG00000059758.7	7.16	9.47	8.32	ENCSR985KAT
K562	CDK17	ENSG00000059758.7	20.05	23.63	21.84	ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.

eCLIP

No eCLIP experiment available

Antibody Validation

No Antibody Primary Validation image or Secondary image available

KD RNA-Seq

No KD RNA-Seq experiment available

RNA Bind-n-Seqn

No RBNS experiment available

Localization Image in HepG2

No Localization Information available

RBP	Antibody Info	Primary-HepG2	Secondary-HepG2	Primary-K562	Secondary-K562	Primary-UBERON	Primary-Hela

Summary
Proteins Bound to RBP RNA

RNA Targets

eCLIP assay for CDK17 is not avaliable on ENCORE database.

Proteins bound to RNA

CDK17 RNA is bound by 29 proteins.

eCLIP assay for CDK17 is not avaliable on ENCORE database.

29 proteins are bound to CDK17 RNA:

Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name
chr12	96672363	96672401	-	3'-UTR,intron-Distal	4.65535	4.44205	K562	PUM2
chr12	96672052	96672140	-	3'-UTR,intron-Distal	4.14617	8.55611	K562	KHSRP
chr12	96717772	96717885	-	3'-UTR,CDS,intron-Distal	3.06734	5.99957	HepG2	BCLAF1
chr12	96672573	96672631	-	3'-UTR,intron-Distal	3.02958	4.90692	K562	PUM2
chr12	96672435	96672488	-	3'-UTR,intron-Distal	3.10879	4.44589	K562	PUM2
chr12	96672576	96672627	-	3'-UTR,intron-Distal	4.86630	5.78691	HepG2	FUBP3
chr12	96674518	96674588	-	3'-UTR,CDS,intron-Distal,intron-Proximal	3.70760	5.35619	K562	AQR
chr12	96673079	96673141	-	3'-UTR,intron-Distal	4.93872	4.95154	K562	ZC3H11A
chr12	96672409	96672480	-	3'-UTR,intron-Distal	3.48072	4.28919	HepG2	KHSRP
chr12	96672140	96672256	-	3'-UTR,intron-Distal	3.16684	6.88763	K562	KHSRP
chr12	96793030	96793088	-	5'-UTR,intron-Distal	3.75199	5.81451	K562	CSTF2T
chr12	96793153	96793234	-	5'-UTR,intron-Distal,intron-Proximal	4.73150	6.63070	HepG2	NKRF
chr12	96793798	96793853	-	5'-UTR,intron-Distal,intron-Proximal	3.36437	3.04831	K562	RBM15
chr12	96793016	96793059	-	5'-UTR,intron-Distal	4.07820	3.06347	K562	NONO
chr12	96793097	96793145	-	5'-UTR,intron-Distal,intron-Proximal	3.93682	3.70058	K562	CSTF2T
chr12	96793166	96793228	-	5'-UTR,intron-Distal,intron-Proximal	3.10238	3.61506	K562	NONO
chr12	96793163	96793238	-	5'-UTR,intron-Distal,intron-Proximal	5.00961	8.72481	HepG2	CSTF2T
chr12	96793145	96793221	-	5'-UTR,intron-Distal,intron-Proximal	4.25199	7.11359	K562	CSTF2T
chr12	96793155	96793237	-	5'-UTR,intron-Distal,intron-Proximal	4.71702	11.91013	K562	GTF2F1
chr12	96793165	96793226	-	5'-UTR,intron-Distal,intron-Proximal	3.94466	3.03048	HepG2	GTF2F1
chr12	96717728	96717772	-	CDS,intron-Distal,intron-Proximal	3.75407	4.76554	HepG2	BCLAF1
chr12	96682945	96683019	-	CDS,intron-Distal,intron-Proximal	3.75556	5.04943	K562	ZNF622
chr12	96717731	96717790	-	CDS,intron-Distal,intron-Proximal	4.48014	5.16052	K562	RBM15
chr12	96683029	96683080	-	CDS,intron-Distal,intron-Proximal	3.63711	4.36528	HepG2	U2AF2
chr12	96707159	96707227	-	CDS,intron-Distal,intron-Proximal	5.80062	12.19672	HepG2	BCLAF1
chr12	96707113	96707159	-	CDS,intron-Distal,intron-Proximal	3.80535	4.46864	HepG2	BCLAF1
chr12	96707101	96707157	-	CDS,intron-Distal,intron-Proximal	3.52713	4.20387	K562	ZNF622
chr12	96688699	96688789	-	CDS,intron-Distal,intron-Proximal	3.38443	3.47285	K562	PRPF8
chr12	96683023	96683079	-	CDS,intron-Distal,intron-Proximal	3.94514	6.86521	K562	U2AF2
chr12	96674623	96674667	-	CDS,intron-Distal,intron-Proximal	3.16468	3.26275	K562	BUD13
chr12	96692651	96692731	-	CDS,intron-Distal	4.13344	9.09836	HepG2	BCLAF1
chr12	96694080	96694136	-	CDS,intron-Distal,intron-Proximal	3.17059	4.74755	K562	ZNF622
chr12	96704893	96704953	-	CDS,intron-Distal	3.11390	3.17233	HepG2	BCLAF1
chr12	96674633	96674714	-	CDS,intron-Distal,intron-Proximal	3.86168	9.01749	K562	SF3B4
chr12	96717733	96717783	-	CDS,intron-Distal,intron-Proximal	3.30211	5.04943	K562	ZNF622
chr12	96707157	96707217	-	CDS,intron-Distal,intron-Proximal	3.85188	5.08507	K562	ZNF622
chr12	96776446	96776505	-	intron-Distal	4.23948	11.23387	K562	EXOSC5
chr12	96793410	96793462	-	intron-Distal	3.30557	4.21158	HepG2	CSTF2T
chr12	96793237	96793341	-	intron-Distal,intron-Proximal	5.48049	13.05195	HepG2	PRPF4
chr12	96704116	96704182	-	intron-Distal	5.05297	7.17304	K562	KHSRP
chr12	96751753	96751853	-	intron-Distal	4.61865	3.50357	HepG2	QKI
chr12	96793469	96793546	-	intron-Distal	3.27481	6.12137	K562	CSTF2T
chr12	96793585	96793670	-	intron-Distal	4.40779	3.86024	K562	EWSR1
chr12	96786201	96786285	-	intron-Distal	3.80311	5.56048	K562	KHSRP
chr12	96793394	96793469	-	intron-Distal	3.31838	3.50009	K562	CSTF2T
chr12	96728373	96728438	-	intron-Distal,intron-Proximal	4.99884	7.50107	K562	AQR
chr12	96793612	96793689	-	intron-Distal	3.45774	3.46130	HepG2	PRPF4
chr12	96776875	96776937	-	intron-Distal	5.42767	9.02435	K562	EXOSC5
chr12	96735990	96736118	-	intron-Distal	3.83057	7.34371	K562	KHSRP
chr12	96777567	96777657	-	intron-Distal	3.84103	8.17294	K562	EXOSC5
chr12	96780141	96780238	-	intron-Distal	4.60811	3.95871	HepG2	ILF3
chr12	96676195	96676279	-	intron-Distal,intron-Proximal	3.59417	3.95214	K562	GPKOW
chr12	96685695	96685794	-	intron-Distal	4.07770	11.86409	K562	PTBP1
chr12	96776761	96776830	-	intron-Distal	5.52483	11.00212	K562	EXOSC5
chr12	96741272	96741364	-	intron-Distal	3.49690	5.85087	K562	ILF3
chr12	96728438	96728497	-	intron-Distal,intron-Proximal	6.38148	13.72936	K562	AQR
chr12	96676199	96676248	-	intron-Distal,intron-Proximal	3.02995	3.89662	K562	BUD13
chr12	96791282	96791367	-	intron-Distal	4.74561	6.93191	K562	KHSRP
chr12	96765696	96765792	-	intron-Distal	4.22049	3.14791	K562	HNRNPL
chr12	96793234	96793343	-	intron-Distal,intron-Proximal	5.70402	9.30937	HepG2	FAM120A
chr12	96777383	96777446	-	intron-Distal	4.15019	3.79026	K562	HNRNPM
chr12	96793250	96793301	-	intron-Distal,intron-Proximal	3.26157	3.84340	K562	CSTF2T
chr12	96793190	96793237	-	intron-Distal,intron-Proximal	4.47889	5.83275	HepG2	PRPF4
chr12	96703809	96703927	-	intron-Distal	5.07311	15.54337	K562	KHSRP
chr12	96706356	96706470	-	intron-Distal	3.89824	5.35459	K562	KHSRP
chr12	96710976	96711026	-	intron-Distal	4.25798	3.98115	K562	MATR3
chr12	96676182	96676263	-	intron-Distal,intron-Proximal	4.89234	8.52787	K562	AQR
chr12	96777731	96777761	-	intron-Distal	4.09730	3.01456	K562	EXOSC5
chr12	96751688	96751745	-	intron-Distal	3.29372	3.51696	K562	KHSRP
chr12	96735190	96735287	-	intron-Distal	3.17374	4.08064	K562	KHSRP
chr12	96741265	96741361	-	intron-Distal	6.22982	19.36052	HepG2	PCBP2
chr12	96777395	96777438	-	intron-Distal	5.17754	7.06134	K562	EXOSC5
chr12	96793238	96793312	-	intron-Distal,intron-Proximal	3.45820	6.96229	HepG2	CSTF2T
chr12	96751737	96751855	-	intron-Distal	5.61901	5.61339	K562	QKI
chr12	96793399	96793467	-	intron-Distal	3.16800	3.14365	K562	NONO
chr12	96793565	96793639	-	intron-Distal	3.30692	4.25264	K562	NONO
chr12	96685694	96685820	-	intron-Distal	4.32232	5.07626	HepG2	PTBP1
chr12	96709647	96709709	-	intron-Distal	3.29950	3.43875	K562	EXOSC5
chr12	96777803	96777851	-	intron-Distal	4.38446	7.01277	K562	EXOSC5
chr12	96776068	96776124	-	intron-Distal	4.26950	7.31365	K562	EXOSC5
chr12	96793594	96793654	-	intron-Distal	4.09444	3.86455	HepG2	GTF2F1
chr12	96703929	96704008	-	intron-Distal	3.75065	10.93931	K562	KHSRP
chr12	96717919	96717974	-	intron-Distal,intron-Proximal	5.38665	6.14157	K562	GPKOW
chr12	96793578	96793670	-	intron-Distal	4.89841	7.09999	HepG2	CSTF2T
chr12	96786112	96786168	-	intron-Distal	4.24286	3.79000	HepG2	U2AF2
chr12	96793249	96793315	-	intron-Distal,intron-Proximal	3.80040	5.24056	K562	GTF2F1
chr12	96717913	96717989	-	intron-Distal,intron-Proximal	4.73670	15.12840	K562	AQR
chr12	96741258	96741361	-	intron-Distal	4.24825	4.70992	HepG2	DDX59
chr12	96710981	96711024	-	intron-Distal	4.52460	3.92866	K562	PTBP1
chr12	96788063	96788134	-	intron-Distal	3.13251	3.90146	K562	KHSRP
chr12	96793482	96793540	-	intron-Distal	4.44257	5.34533	K562	NONO
chr12	96793490	96793562	-	intron-Distal	4.10395	3.30336	K562	EWSR1
chr12	96753359	96753516	-	intron-Distal	3.77878	7.12499	K562	KHSRP
Chr	Start	End	Strand	Matched Area	log2(fold change)	-log(p-value)	Cell Line	Binding Protein Name

eCLIP assay for CDK17 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout assay for CDK17 is not available on ENCORE database.
58 RBPs can affect the levels of CDK17.

The Knockdown/knockout RNA-Seq assay for CDK17 is not available on ENCORE database.

58 RBPs can affect the gene expression of CDK17 :

Gene Name	Gene ID	KDMean	CNMean	log2(fold change) *	-log(pval) **	-log(padj) **	Cell Line	Affected by RBP	Bound by RBP
CDK17	ENSG00000059758.3	328.64000	466.88380	-0.50660	3.11330	2.06100	HepG2	ADAR
CDK17	ENSG00000059758.3	244.20540	422.83590	-0.79200	5.42300	4.09760	HepG2	BCCIP
CDK17	ENSG00000059758.3	711.97770	509.97910	0.48130	3.64860	2.97240	HepG2	BOP1
CDK17	ENSG00000059758.3	301.65400	468.19570	-0.63420	4.32880	3.48580	HepG2	CPSF6
CDK17	ENSG00000059758.3	389.72980	521.54670	-0.42030	3.88750	2.92000	HepG2	DDX19B
CDK17	ENSG00000059758.3	325.44460	449.43240	-0.46570	2.86140	2.17300	HepG2	DDX21
CDK17	ENSG00000059758.3	403.23610	539.50120	-0.42000	3.26900	2.54270	HepG2	DKC1
CDK17	ENSG00000059758.3	876.49010	645.63780	0.44090	3.17730	2.30720	HepG2	EIF4G2
CDK17	ENSG00000059758.3	1233.37010	915.91170	0.42920	5.59500	4.78950	HepG2	ETF1
CDK17	ENSG00000059758.3	352.73770	576.74380	-0.70930	4.44530	3.04970	HepG2	FUS
CDK17	ENSG00000059758.3	610.68000	804.65750	-0.39800	2.46470	1.81070	HepG2	FXR1
CDK17	ENSG00000059758.3	590.27740	792.45370	-0.42490	2.75260	1.86470	HepG2	G3BP2
CDK17	ENSG00000059758.3	314.23720	465.25860	-0.56620	3.03250	1.96300	HepG2	GNB2L1
CDK17	ENSG00000059758.3	403.60900	530.75570	-0.39510	1.89290	1.35680	HepG2	GPKOW
CDK17	ENSG00000059758.3	253.24460	474.62930	-0.90630	8.28960	7.25750	HepG2	HNRNPA1
CDK17	ENSG00000059758.3	521.36650	755.91310	-0.53590	4.13680	3.29690	HepG2	HNRNPK
CDK17	ENSG00000059758.3	265.47760	384.10830	-0.53290	3.48200	2.42290	HepG2	HNRNPM
CDK17	ENSG00000059758.3	424.41310	524.44980	-0.30530	2.04580	1.51520	HepG2	HNRNPU
CDK17	ENSG00000059758.3	522.83070	758.65760	-0.53710	3.87850	3.09160	HepG2	IGF2BP2
CDK17	ENSG00000059758.3	373.17180	535.70760	-0.52160	5.78460	4.75910	HepG2	ILF2
CDK17	ENSG00000059758.3	581.70120	804.93890	-0.46860	3.13110	2.43370	HepG2	MAGOH
CDK17	ENSG00000059758.3	594.05710	809.42600	-0.44630	2.65790	2.03940	HepG2	MATR3
CDK17	ENSG00000059758.3	593.56860	828.47780	-0.48100	3.22940	2.54680	HepG2	NCBP2
CDK17	ENSG00000059758.3	509.67540	677.47490	-0.41060	3.51430	2.65560	HepG2	NOL12
CDK17	ENSG00000059758.3	334.04330	491.52980	-0.55720	2.33950	1.53610	HepG2	PABPC1
CDK17	ENSG00000059758.3	534.53740	747.20020	-0.48320	5.37290	4.57260	HepG2	PCBP1
CDK17	ENSG00000059758.3	1114.99850	526.99380	1.08110	4.11190	3.26070	HepG2	RAVER1
CDK17	ENSG00000059758.3	499.21730	846.14320	-0.76120	11.46730	10.51040	HepG2	NELFE
CDK17	ENSG00000059758.3	548.34140	788.05470	-0.52320	6.03910	5.17710	HepG2	RECQL
CDK17	ENSG00000059758.3	444.71130	317.12060	0.48770	2.06560	1.37720	HepG2	RRP9
CDK17	ENSG00000059758.3	357.42290	467.04390	-0.38590	2.80610	2.15840	HepG2	SAFB2
CDK17	ENSG00000059758.3	444.74130	544.64910	-0.29240	2.08320	1.51320	HepG2	SMN1
CDK17	ENSG00000059758.3	1315.28160	864.64610	0.60510	11.92710	11.08070	HepG2	SRFBP1
CDK17	ENSG00000059758.3	556.17720	672.17940	-0.27330	2.13320	1.63570	HepG2	SRSF9
CDK17	ENSG00000059758.3	405.34490	742.63350	-0.87350	13.12540	12.04010	HepG2	TAF15
CDK17	ENSG00000059758.3	354.69410	509.58940	-0.52280	4.14570	3.56020	HepG2	TIAL1
CDK17	ENSG00000059758.3	340.98420	514.15720	-0.59250	6.16710	5.38510	HepG2	TRIM56
CDK17	ENSG00000059758.3	246.64070	378.85430	-0.61920	2.81050	1.79700	HepG2	UPF2
CDK17	ENSG00000059758.3	178.03990	407.38580	-1.19420	11.06670	9.63280	HepG2	XRN2
CDK17	ENSG00000059758.3	1350.02510	996.84490	0.43740	6.15620	5.36130	K562	AGGF1
CDK17	ENSG00000059758.3	1351.16340	1037.25500	0.38130	3.23960	2.53120	K562	AKAP8L
CDK17	ENSG00000059758.3	870.05350	664.85400	0.38800	2.48240	1.65850	K562	BOP1
CDK17	ENSG00000059758.3	508.29520	706.91820	-0.47590	3.88220	2.95460	K562	CPSF6
CDK17	ENSG00000059758.3	1363.51170	1143.82070	0.25340	2.50520	1.88090	K562	DDX47
CDK17	ENSG00000059758.3	887.39290	634.26070	0.48440	3.34760	2.20230	K562	EIF3D
CDK17	ENSG00000059758.3	1704.47000	1445.23140	0.23790	2.60090	1.68720	K562	EIF4G2
CDK17	ENSG00000059758.3	700.67150	521.15300	0.42690	2.63070	1.53690	K562	FKBP4
CDK17	ENSG00000059758.3	1343.39390	787.31950	0.77080	3.56430	2.12320	K562	HNRNPA2B1
CDK17	ENSG00000059758.3	358.08310	685.39380	-0.93660	9.06970	7.20380	K562	HNRNPM
CDK17	ENSG00000059758.3	765.12390	970.60050	-0.34320	2.64740	1.82540	K562	MAGOH
CDK17	ENSG00000059758.3	1347.13530	864.37070	0.64010	2.03720	1.30240	K562	NAA15
CDK17	ENSG00000059758.3	688.33860	945.95090	-0.45860	3.63460	2.67550	K562	PPIG
CDK17	ENSG00000059758.3	389.97880	538.24650	-0.46490	2.55230	1.68930	K562	PSIP1
CDK17	ENSG00000059758.3	770.35590	942.96780	-0.29170	2.13170	1.53590	K562	PTBP1
CDK17	ENSG00000059758.3	1897.33680	1028.72460	0.88300	13.69680	12.53490	K562	PUS1
CDK17	ENSG00000059758.3	1532.22290	1002.29390	0.61220	10.01440	8.91290	K562	RBM15
CDK17	ENSG00000059758.3	370.69070	491.06750	-0.40570	2.47680	1.54340	K562	RCC2
CDK17	ENSG00000059758.3	1424.13020	864.86350	0.71940	2.94160	1.45600	K562	SUPT6H
CDK17	ENSG00000059758.3	675.61210	935.63010	-0.46970	1.98570	1.37900	K562	TARDBP
CDK17	ENSG00000059758.3	715.09170	902.49420	-0.33580	2.33860	1.59400	K562	TIA1
CDK17	ENSG00000059758.3	1029.37450	802.08070	0.35980	2.83290	2.01980	K562	U2AF2
CDK17	ENSG00000059758.3	1006.30080	814.89950	0.30430	2.20090	1.42040	K562	WDR3
CDK17	ENSG00000059758.3	446.79900	601.40050	-0.42870	2.47230	1.34980	K562	XRN2
CDK17	ENSG00000059758.3	1401.85190	850.88870	0.72020	2.99310	1.32980	K562	YTHDC2
Gene Name	Gene ID	KDMean	CNMean	log2(fold change)	-log(pval)	-log(padj)	Cell Line	Affected by RBP	Bound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

The Knockdown/knockout RNA-Seq assay for CDK17 is not available on ENCORE database.

3 RBPs can affect the splicing of CDK17 :

Event Type	Gene Name	Gene ID	chr	Strand	ExonStart	ExonEnd	2ndExonStart	2ndExonEnd	upstreamES	upstreamEE	downstreamES	downstreamEE	dPSI	p-value	FDR	is_included	Cell Line	Affected by RBP
SE	CDK17	ENSG00000059758.3	chr12	-	96692646	96692761			96691404	96691499	96694081	96694138	-0.08100	0.00798	0.06784	excluded	K562	AQR
SE	CDK17	ENSG00000059758.3	chr12	-	96691047	96691110			96688776	96688900	96691404	96691499	-0.09600	0.00439	0.08402	excluded	K562	AGGF1
SE	CDK17	ENSG00000059758.3	chr12	-	96691047	96691110			96688776	96688900	96691404	96691499	-0.15700	0.00320	0.09631	excluded	K562	SF3B1
MXE	CDK17	ENSG00000059758.3	chr12	-	96688776	96688900	96691047	96691110	96683035	96683065	96691404	96691499	-0.19800	0.00021	0.01180	2included	K562	AGGF1
MXE	CDK17	ENSG00000059758.3	chr12	-	96688767	96688900	96691047	96691110	96683035	96683065	96691404	96691499	-0.16500	0.00183	0.05670	2included	K562	AGGF1

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".

CDK17

General Information

Functions

Localization

Domains (AlphaFold: CDK17)

Antibody Validation

Expression Level in Cell lines

Assays

RNA Targets

Proteins bound to RNA

eCLIP assay for CDK17 is not avaliable on ENCORE database.

29 proteins are bound to CDK17 RNA:

eCLIP assay for CDK17 is not avaliable on ENCORE database.

Diffrential Expression

The Knockdown/knockout RNA-Seq assay for CDK17 is not available on ENCORE database.

58 RBPs can affect the gene expression of CDK17 :

The Knockdown/knockout RNA-Seq assay for CDK17 is not available on ENCORE database.

3 RBPs can affect the splicing of CDK17 :

The Knockdown/knockout RNA-Seq assay for CDK17 is not avaliable on ENCORE database.