FAM76B

General Information

Gene Name       : FAM76B
Gene ID             : ENSG00000077458.12
Essential Gene : No

Functions

Localization

Domains (AlphaFold: FAM76B)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878FAM76BENSG00000077458.1230.1422.1126.12ENCSR000AEF
HepG2FAM76BENSG00000077458.1214.5918.3516.47ENCSR985KAT
K562FAM76BENSG00000077458.1226.1823.5724.88ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for FAM76B is not avaliable on ENCORE database.



Proteins bound to RNA
  • FAM76B RNA is bound by 29 proteins.  







eCLIP assay for FAM76B is not avaliable on ENCORE database.





29 proteins are bound to FAM76B RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr119550403095504087-3'-UTR,intron-Distal4.182173.37821K562XRCC6
chr119550227595502354-3'-UTR,intron-Distal3.926416.19377K562KHSRP
chr119550275895502809-3'-UTR,intron-Distal3.513833.88742K562FAM120A
chr119552078795520832-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.128154.14618K562ZNF622
chr119550908195509187-3'-UTR,CDS,intron-Distal,intron-Proximal4.139076.65960HepG2BCLAF1
chr119550407495504114-3'-UTR,intron-Distal3.8449610.16833K562KHSRP
chr119551200795512075-3'-UTR,CDS,intron-Distal3.113903.55800HepG2BCLAF1
chr119551928195519381-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal4.0521512.81426K562ZNF622
chr119551205495512134-3'-UTR,CDS,intron-Distal,intron-Proximal4.395423.93061K562U2AF2
chr119550397295504027-3'-UTR,intron-Distal3.988959.89511K562KHSRP
chr119550474795504812-3'-UTR,CDS,intron-Distal,intron-Proximal4.359824.34038HepG2BCLAF1
chr119550397095504024-3'-UTR,intron-Distal3.755185.53561K562PUM2
chr119551935395519437-3'-UTR,5'-UTR,CDS,intron-Distal3.397215.45876HepG2BCLAF1
chr119550215695502227-3'-UTR,intron-Distal3.546345.32884K562KHSRP
chr119550378895503849-3'-UTR,intron-Distal3.7318111.77432K562KHSRP
chr119550908595509174-3'-UTR,CDS,intron-Distal,intron-Proximal3.057144.56310K562ZNF622
chr119552166295521746-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal4.427167.93461K562BUD13
chr119552168695521782-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal4.8968728.45893K562SF3B4
chr119550384995503895-3'-UTR,intron-Distal4.3695710.71730K562KHSRP
chr119551216595512259-3'-UTR,intron-Distal,intron-Proximal3.171403.54602K562TIA1
chr119550389595503954-3'-UTR,intron-Distal3.874369.94478K562KHSRP
chr119550380295503868-3'-UTR,intron-Distal4.343763.83835HepG2FUBP3
chr119550411495504158-3'-UTR,intron-Distal4.4237811.34175K562KHSRP
chr119552166695521761-3'-UTR,5'-UTR,CDS,intron-Distal,intron-Proximal3.588136.00860K562SMNDC1
chr119550390095503959-3'-UTR,intron-Distal4.351518.73210K562PUM2
chr119552326695523337-5'-UTR,intron-Distal3.238343.18246K562PRPF8
chr119552269495522736-5'-UTR,intron-Distal,intron-Proximal3.170813.17151K562UCHL5
chr119552267995522758-5'-UTR,intron-Distal,intron-Proximal3.9508310.72776K562CSTF2T
chr119552339895523539-5'-UTR,intron-Distal3.875943.07217HepG2NCBP2
chr119552266395522757-5'-UTR,intron-Distal,intron-Proximal3.9654711.96691HepG2PRPF4
chr119552267395522746-5'-UTR,intron-Distal,intron-Proximal4.181633.03048HepG2GTF2F1
chr119552275795522842-5'-UTR,intron-Distal,intron-Proximal5.6004312.13389HepG2PRPF4
chr119552268595522765-5'-UTR,intron-Distal,intron-Proximal3.234474.93358K562XRCC6
chr119552343395523496-5'-UTR,intron-Distal3.475843.66187K562ZNF622
chr119552265095522767-5'-UTR,intron-Distal,intron-Proximal4.558715.35746HepG2DDX3X
chr119551984395519893-5'-UTR,intron-Distal4.070523.45805K562KHSRP
chr119552330395523343-5'-UTR,intron-Distal4.117853.81597K562RBM15
chr119552267695522750-5'-UTR,intron-Distal,intron-Proximal4.4179814.41453K562GEMIN5
chr119552276895522845-5'-UTR,intron-Distal,intron-Proximal3.337866.13390K562GEMIN5
chr119552266295522749-5'-UTR,intron-Distal,intron-Proximal4.354414.36718HepG2NKRF
chr119552269095522748-5'-UTR,intron-Distal,intron-Proximal4.191389.36714K562GTF2F1
chr119552266195522745-5'-UTR,intron-Distal,intron-Proximal3.924818.84051K562DROSHA
chr119552269495522752-5'-UTR,intron-Distal,intron-Proximal4.854893.44348K562DDX6
chr119552267295522843-5'-UTR,intron-Distal,intron-Proximal3.347514.31701K562FUS
chr119552266195522748-5'-UTR,intron-Distal,intron-Proximal3.036016.20855K562AKAP8L
chr119551304095513080-CDS,intron-Distal,intron-Proximal4.7153416.08542K562ZNF622
chr119551622495516352-CDS,intron-Distal,intron-Proximal4.966298.64103HepG2GRWD1
chr119551307695513092-CDS,intron-Distal,intron-Proximal4.013067.79455K562UCHL5
chr119551624195516262-CDS,intron-Distal4.4133113.72753K562ZNF622
chr119551304195513092-CDS,intron-Distal,intron-Proximal3.872793.31827HepG2GRWD1
chr119551636595516411-CDS,intron-Distal3.304526.78413K562ZNF622
chr119551622695516327-CDS,intron-Distal,intron-Proximal3.8283311.63522K562UCHL5
chr119551622695516241-CDS,intron-Distal,intron-Proximal6.0104315.16898K562ZNF622
chr119551641195516428-CDS,intron-Distal3.617146.44455K562ZNF622
chr119551304195513076-CDS,intron-Distal,intron-Proximal4.2054010.26568K562UCHL5
chr119551278495512852-CDS,intron-Distal,intron-Proximal4.5548815.40956K562ZNF622
chr119551636695516429-CDS,intron-Distal,intron-Proximal4.2054010.82143K562UCHL5
chr119551279995512852-CDS,intron-Distal,intron-Proximal4.1504911.37918K562UCHL5
chr119551626295516331-CDS,intron-Distal,intron-Proximal3.8128511.14477K562ZNF622
chr119551637095516425-CDS,intron-Distal3.530343.68471HepG2BCLAF1
chr119551275095512799-CDS,intron-Distal,intron-Proximal3.306144.59873K562UCHL5
chr119551304295513095-CDS,intron-Distal,intron-Proximal3.580343.87469HepG2BCLAF1
chr119551308095513092-CDS,intron-Distal,intron-Proximal4.3204812.39089K562ZNF622
chr119551927995519307-CDS,intron-Distal,intron-Proximal3.144585.71803K562UCHL5
chr119551212995512168-intron-Distal,intron-Proximal4.519433.42835K562SF3B4
chr119552224895522324-intron-Distal,intron-Proximal3.665255.55220K562CSTF2T
chr119552192695521985-intron-Distal,intron-Proximal4.661156.89148K562TIA1
chr119551610695516152-intron-Distal,intron-Proximal4.073683.02181K562PRPF8
chr119551611395516204-intron-Distal,intron-Proximal4.022905.98773K562KHSRP
chr119552224495522330-intron-Distal,intron-Proximal3.388763.41462K562EWSR1
chr119552248795522535-intron-Distal3.807383.94787K562AQR
chr119551297795513042-intron-Distal,intron-Proximal4.667364.13847K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for FAM76B is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for FAM76B is not available on ENCORE database.

  • 54 RBPs can affect the levels of FAM76B.  








The Knockdown/knockout RNA-Seq assay for FAM76B is not available on ENCORE database.





54 RBPs can affect the gene expression of FAM76B :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
FAM76BENSG00000077458.8306.73330535.82980-0.804805.411804.69710HepG2AKAP1
FAM76BENSG00000077458.8332.50490437.52780-0.396002.721001.96030HepG2AKAP8L
FAM76BENSG00000077458.8283.54780443.37660-0.644903.512502.62920HepG2ASCC1
FAM76BENSG00000077458.8290.40930421.43000-0.537202.278501.43250HepG2BCCIP
FAM76BENSG00000077458.8372.37500657.11490-0.819408.346607.37530HepG2BOP1
FAM76BENSG00000077458.8430.59580603.27440-0.486503.092902.37110HepG2CPSF6
FAM76BENSG00000077458.8460.77460634.36320-0.461204.033603.28420HepG2CELF1
FAM76BENSG00000077458.8518.20620682.04140-0.396303.783802.94020HepG2DAZAP1
FAM76BENSG00000077458.8286.85350513.33250-0.839603.865803.13740HepG2DDX3X
FAM76BENSG00000077458.8297.18290440.84990-0.568902.960602.32380HepG2DDX6
FAM76BENSG00000077458.8233.48360335.25000-0.521903.311102.54640HepG2DNAJC21
FAM76BENSG00000077458.8366.58470208.052700.817103.365202.50250HepG2FUBP3
FAM76BENSG00000077458.8345.26090683.87810-0.986109.585208.44190HepG2GPKOW
FAM76BENSG00000077458.8424.46610621.27090-0.549606.155205.18460HepG2HNRNPL
FAM76BENSG00000077458.8404.08740645.61580-0.676006.247705.40000HepG2PUF60
FAM76BENSG00000077458.8521.32260405.906400.360902.235301.66370HepG2QKI
FAM76BENSG00000077458.8807.69240597.690100.434304.133603.53290HepG2RBM22
FAM76BENSG00000077458.8489.93160368.391900.411202.516801.87040HepG2RBM25
FAM76BENSG00000077458.8380.78150518.79260-0.446202.201801.32620HepG2RBM27
FAM76BENSG00000077458.8579.46780417.114600.474203.958903.33380HepG2NELFE
FAM76BENSG00000077458.8564.65850388.496400.539404.987904.19050HepG2RECQL
FAM76BENSG00000077458.8244.35250333.56680-0.449002.324601.75610HepG2RPS19
FAM76BENSG00000077458.8491.64290619.08140-0.332502.573001.89320HepG2SLBP
FAM76BENSG00000077458.8337.82380445.51260-0.399202.449701.79200HepG2SRSF7
FAM76BENSG00000077458.8603.97350724.96410-0.263401.903101.36950HepG2SUCLG1
FAM76BENSG00000077458.8237.95590412.49230-0.793704.311403.49360HepG2SUPV3L1
FAM76BENSG00000077458.8538.00050366.108200.555204.089203.42820HepG2TAF15
FAM76BENSG00000077458.8181.61930276.49580-0.606302.477201.52770HepG2TFIP11
FAM76BENSG00000077458.8476.30560336.388100.501703.747902.78230HepG2TIA1
FAM76BENSG00000077458.8584.79570449.757400.378702.156601.59550HepG2U2AF1
FAM76BENSG00000077458.8600.08090395.652900.600803.157601.80330HepG2XRCC5
FAM76BENSG00000077458.8236.53160406.05270-0.779604.587103.66230HepG2XRN2
FAM76BENSG00000077458.81983.101401360.962500.5430011.5254010.46140K562AGGF1
FAM76BENSG00000077458.81859.124001378.356900.431604.194403.50110K562AQR
FAM76BENSG00000077458.82633.321501995.936300.399705.110003.77450K562CELF1
FAM76BENSG00000077458.8580.85770836.44880-0.526102.908201.83930K562DDX3X
FAM76BENSG00000077458.8983.197101372.74940-0.481507.363306.36960K562DDX47
FAM76BENSG00000077458.8600.42450773.85000-0.366103.129902.28510K562EIF3G
FAM76BENSG00000077458.8785.32530600.417900.387202.391301.35440K562FKBP4
FAM76BENSG00000077458.8627.38340908.84970-0.534704.576103.82490K562FXR1
FAM76BENSG00000077458.82089.609701236.755900.756603.686102.20970K562HNRNPA2B1
FAM76BENSG00000077458.8855.132001240.65450-0.536905.796204.21110K562HNRNPL
FAM76BENSG00000077458.81007.923201256.61700-0.318202.222401.50640K562HSPD1
FAM76BENSG00000077458.82119.766001502.858700.496105.260704.04820K562KIF1C
FAM76BENSG00000077458.8894.487901122.06780-0.327002.659301.75540K562MATR3
FAM76BENSG00000077458.8409.07050603.48390-0.561003.824502.24290K562NONO
FAM76BENSG00000077458.8783.512701052.13290-0.425303.452802.52120K562PPIG
FAM76BENSG00000077458.8654.430201092.32650-0.7391010.942309.68510K562PTBP1
FAM76BENSG00000077458.82119.479801404.367300.593706.879706.06850K562PUS1
FAM76BENSG00000077458.81947.799901368.400300.509308.287707.28930K562RBM15
FAM76BENSG00000077458.8346.46150607.03700-0.809106.377805.12560K562RPS19
FAM76BENSG00000077458.8594.49700945.84590-0.669903.053301.99620K562RPS3
FAM76BENSG00000077458.81996.841901136.088900.813503.319101.92440K562SNRNP200
FAM76BENSG00000077458.8530.136101070.81950-1.0143017.5581015.79760K562SRSF1
FAM76BENSG00000077458.81019.08890798.227000.352303.197801.80040K562SSB
FAM76BENSG00000077458.81331.710801017.872000.387604.040503.07030K562U2AF2
FAM76BENSG00000077458.81125.28750919.322400.291602.131501.36450K562WDR3
FAM76BENSG00000077458.82157.439401336.907800.690302.951701.30600K562YTHDC2
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for FAM76B is not available on ENCORE database.





14 RBPs can affect the splicing of FAM76B :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEFAM76BENSG00000077458.8chr11-9551227295512299955119859551212195512770955128510.305000.006810.09643includedK562SRSF1
SEFAM76BENSG00000077458.8chr11-955122419551229995511999955121189551277095512851-0.200000.001500.04342excludedK562AKAP8L
SEFAM76BENSG00000077458.8chr11-9551224195512299955119859551212195512770955128510.552000.000000.00001includedHepG2HNRNPK
SEFAM76BENSG00000077458.8chr11-955122419551229995511999955121189551277095512851-0.443000.001200.08396excludedHepG2TBRG4
SEFAM76BENSG00000077458.8chr11-955122419551229995511985955121219551277095512851-0.304000.000000.00000excludedK562AQR
SEFAM76BENSG00000077458.8chr11-955122419551229995511985955121219551277095512851-0.238000.002390.07613excludedK562FXR1
SEFAM76BENSG00000077458.8chr11-955122419551229995511985955121219551277095512851-0.224000.002190.03236excludedK562PUS1
SEFAM76BENSG00000077458.8chr11-9551224195512299955119999551211895512770955128510.200000.001550.08099includedHepG2FTO
SEFAM76BENSG00000077458.8chr11-955122419551229995511985955121219551277095512851-0.248000.000000.00248excludedK562APOBEC3C
SEFAM76BENSG00000077458.8chr11-9551224195512299955119859551212195512770955128510.401000.000160.01962includedHepG2DDX6
SEFAM76BENSG00000077458.8chr11-9551224195512299955119859551212195512770955128510.401000.000450.04711includedHepG2SUPV3L1
SEFAM76BENSG00000077458.8chr11-955122419551229995511985955121219551277095512851-0.342000.000110.00794excludedHepG2PCBP1
A3SSFAM76BENSG00000077458.8chr11-955119859551212195511985955121189551277095512851-0.109000.001210.09094shorterK562AKAP8L
A3SSFAM76BENSG00000077458.8chr11-9551928295519462955192829551943895520787955208420.080000.001550.05399longerK562U2AF2
A3SSFAM76BENSG00000077458.8chr11-9551622895516472955162289551642895519282955194620.052000.000450.00343longerK562AQR
A3SSFAM76BENSG00000077458.8chr11-9551934695519462955193469551943895520787955208420.259000.000000.00000longerK562AQR
A3SSFAM76BENSG00000077458.8chr11-9551304295513156955130429551309095516228955163810.117000.000000.00000longerK562AQR
A3SSFAM76BENSG00000077458.8chr11-9551928295519462955192829551943895520787955208420.054000.000600.03192longerK562PUS1
A3SSFAM76BENSG00000077458.8chr11-955119859551212195511985955121189551277095512851-0.092000.002240.09037shorterK562PUS1
A3SSFAM76BENSG00000077458.8chr11-955119859551212195511985955121189551277095512851-0.153000.000370.06462shorterHepG2SFPQ

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for FAM76B is not avaliable on ENCORE database.