WDR18

General Information

Gene Name       : WDR18
Gene ID             : ENSG00000065268.10
Essential Gene : Yes

Functions

Localization

Domains (AlphaFold: WDR18)


Antibody Validation

Expression Level in Cell lines

Cell Line Gene Name Ensembl ID Rep1 TPM Rep2 TPM Average TPM Experiment ID
Gm12878WDR18ENSG00000065268.102.825.974.39ENCSR000AEF
HepG2WDR18ENSG00000065268.1054.1510.0532.10ENCSR985KAT
K562WDR18ENSG00000065268.1038.2410.9824.61ENCSR000AEO

Assays

0 Released experiments are available on ENCORE database.







  eCLIP  

No eCLIP experiment available



  Antibody Validation  

No Antibody Primary Validation image or Secondary image available



  KD RNA-Seq  

No KD RNA-Seq experiment available



  RNA Bind-n-Seqn  

No RBNS experiment available



  Localization Image in HepG2  

No Localization Information available













RBP Antibody InfoPrimary-HepG2Secondary-HepG2Primary-K562Secondary-K562Primary-UBERONPrimary-Hela








RNA Targets

  • eCLIP assay for WDR18 is not avaliable on ENCORE database.



Proteins bound to RNA
  • WDR18 RNA is bound by 15 proteins.  







eCLIP assay for WDR18 is not avaliable on ENCORE database.





15 proteins are bound to WDR18 RNA:

Chr Start End Strand Matched Area log2(fold change) -log(p-value) Cell Line Binding Protein Name
chr19990339990427+3'-UTR,CDS,intron-Proximal3.7968614.87703HepG2PRPF8
chr19990171990235+3'-UTR,CDS,intron-Proximal3.3472110.30039HepG2SF3B4
chr19989988990069+3'-UTR,intron-Distal,intron-Proximal3.391473.13705K562BUD13
chr19991087991129+3'-UTR,CDS3.717413.59112HepG2PPIG
chr19989820989894+3'-UTR,CDS4.0993314.66124HepG2PPIG
chr19994211994266+3'-UTR,CDS,intron-Proximal3.127985.74131HepG2PPIG
chr19994454994541+3'-UTR4.425967.36168HepG2SUB1
chr19992037992046+3'-UTR,5'-UTR,CDS3.591765.95764K562YBX3
chr19989846989894+3'-UTR,CDS4.875197.85193K562YBX3
chr19994305994380+3'-UTR,CDS3.586094.30833K562PABPC4
chr19989961990080+3'-UTR,intron-Distal,intron-Proximal3.090809.12242HepG2RBFOX2
chr19991910991993+3'-UTR,CDS,intron-Proximal4.503428.69518HepG2DROSHA
chr19994210994267+3'-UTR,CDS,intron-Proximal3.109133.81236HepG2SRSF1
chr19991895991977+3'-UTR,CDS,intron-Proximal6.3534839.71920HepG2RBFOX2
chr19994444994517+3'-UTR5.1340513.44822K562PABPC4
chr19992037992088+3'-UTR,5'-UTR,CDS3.468483.84718K562METAP2
chr19991905992007+3'-UTR,5'-UTR,CDS,intron-Proximal4.4688314.84738K562RBFOX2
chr19989997990046+3'-UTR,intron-Distal5.245649.15113HepG2PPIG
chr19991908991982+3'-UTR,CDS,intron-Proximal5.364998.26505HepG2PRPF8
chr19994001994058+3'-UTR,CDS,intron-Distal,intron-Proximal3.164683.26275K562BUD13
chr19992104992202+3'-UTR,5'-UTR,CDS,intron-Proximal4.445568.01338K562AQR
chr19991347991391+3'-UTR,CDS,intron-Proximal5.066475.01842HepG2PRPF8
chr19991897991981+3'-UTR,CDS,intron-Proximal6.8146444.92138K562DROSHA
chr19990795990871+3'-UTR,CDS,intron-Distal,intron-Proximal3.154505.08270HepG2SF3B4
chr19992018992124+3'-UTR,5'-UTR,CDS,intron-Proximal3.741555.42514HepG2RPS3
chr19984464984564+CDS,intron-Distal,intron-Proximal4.287649.87549K562LIN28B
chr19989707989763+CDS,intron-Proximal4.501508.05832K562SF3B4
chr19985899985954+CDS,intron-Distal3.227257.44878K562YBX3
chr19985879985899+CDS,intron-Distal4.276374.32914K562YBX3
chr19985864985880+CDS,intron-Distal,intron-Proximal3.070753.07411K562LIN28B
chr19985893985960+CDS,intron-Distal4.218429.27186HepG2PPIG
chr19991535991570+intron-Distal6.8859361.05475HepG2RBFOX2
chr19991619991718+intron-Distal4.290136.23256HepG2DROSHA
chr19991775991808+intron-Distal7.7466929.56853K562DROSHA
chr19991774991827+intron-Distal4.906897.25108K562RBFOX2
chr19991840991895+intron-Distal,intron-Proximal7.6988652.77014HepG2RBFOX2
chr19991808991897+intron-Distal,intron-Proximal9.0240379.34406K562DROSHA
chr19992759992827+intron-Distal5.086597.91254K562RBFOX2
chr19992753992790+intron-Distal5.422716.00761K562DROSHA
chr19991625991687+intron-Distal5.270858.81972K562RBFOX2
chr19991707991937+intron-Distal,intron-Proximal5.8548914.70782K562DDX6
chr19991855991910+intron-Distal,intron-Proximal5.146885.85494HepG2DROSHA
chr19991710991775+intron-Distal8.3940744.47370K562DROSHA
chr19991512991604+intron-Distal8.8367868.26053K562DROSHA
chr19991634991690+intron-Distal4.467425.21205K562DDX6
chr19991827991897+intron-Distal,intron-Proximal5.7088012.43358K562RBFOX2
chr19991604991700+intron-Distal7.8192260.54132K562DROSHA
chr19985975986021+intron-Distal,intron-Proximal4.653074.65563K562AQR
chr19992176992224+intron-Distal,intron-Proximal3.313176.23834K562RBFOX2
chr19991524991594+intron-Distal5.4817611.30270K562RBFOX2
chr19991593991715+intron-Distal8.75266125.28821HepG2RBFOX2
chr19991415991491+intron-Distal,intron-Proximal6.0095636.19652HepG2RBFOX2
chr19991491991535+intron-Distal7.4499547.73119HepG2RBFOX2
chr19991570991593+intron-Distal6.1608437.72664HepG2RBFOX2
chr19992927992975+intron-Distal3.837186.05904K562RBFOX2
chr19991500991576+intron-Distal5.528854.52980K562DDX6
chr19991769991840+intron-Distal8.1569082.62662HepG2RBFOX2
chr19991541991613+intron-Distal4.945505.85494HepG2DROSHA
chr19990369990416+intron-Proximal4.929354.65563K562AQR
ChrStartEndStrandMatched Arealog2(fold change)-log(p-value)Cell LineBinding Protein Name




eCLIP assay for WDR18 is not avaliable on ENCORE database.



Diffrential Expression

  • The Knockdown/knockout assay for WDR18 is not available on ENCORE database.

  • 104 RBPs can affect the levels of WDR18.  








The Knockdown/knockout RNA-Seq assay for WDR18 is not available on ENCORE database.





104 RBPs can affect the gene expression of WDR18 :

Gene NameGene IDKDMeanCNMeanlog2(fold change) *-log(pval) **-log(padj) **Cell LineAffected by RBPBound by RBP
WDR18ENSG00000065268.6830.76190699.009100.249002.070901.53020HepG2ACO1
WDR18ENSG00000065268.6131.73240281.38360-1.094908.378707.13940HepG2CALR
WDR18ENSG00000065268.6399.59160698.79850-0.8064013.5544012.31220HepG2CKAP4
WDR18ENSG00000065268.6399.06850146.622401.4444010.619709.15120HepG2CNOT7
WDR18ENSG00000065268.6113.66630268.45040-1.239902.742301.83500HepG2DDX24
WDR18ENSG00000065268.6917.50160520.972800.816404.822404.01460HepG2DDX3X
WDR18ENSG00000065268.6313.58940136.337101.2016012.2253010.83330HepG2DNAJC21
WDR18ENSG00000065268.6306.80930135.145801.1827013.4582012.12840HepG2DNAJC2
WDR18ENSG00000065268.6701.86370478.359200.553003.526002.20380HepG2EIF2S2
WDR18ENSG00000065268.61417.27770990.484900.516803.265002.62040HepG2ETF1
WDR18ENSG00000065268.6533.72920683.00470-0.355802.444601.65970HepG2EWSR1
WDR18ENSG00000065268.6251.62590506.55090-1.0094010.834809.32750HepG2FUBP3
WDR18ENSG00000065268.6733.67770479.994800.612002.133101.52200HepG2FXR1
WDR18ENSG00000065268.6496.34590309.954900.679202.690902.05820HepG2GPKOW
WDR18ENSG00000065268.6219.06080451.19030-1.042402.513201.84550HepG2HNRNPK
WDR18ENSG00000065268.6535.42490308.766900.794105.230504.32860HepG2HNRNPL
WDR18ENSG00000065268.6454.01390295.801400.618001.976601.43630HepG2HNRNPLL
WDR18ENSG00000065268.6243.07040152.094400.676304.310703.56800HepG2HNRNPU
WDR18ENSG00000065268.6221.39190155.358700.510902.554801.84780HepG2ILF2
WDR18ENSG00000065268.6240.98780139.833900.785103.868602.41890HepG2KHDRBS1
WDR18ENSG00000065268.6837.94440638.945500.391104.626103.31480HepG2KIF1C
WDR18ENSG00000065268.6759.22450480.164400.660902.051801.48320HepG2MAGOH
WDR18ENSG00000065268.6866.34980482.777400.843503.065802.40470HepG2MATR3
WDR18ENSG00000065268.6897.48370494.088900.861005.067604.22240HepG2NCBP2
WDR18ENSG00000065268.6545.39190336.098200.698302.785602.01860HepG2NOL12
WDR18ENSG00000065268.6607.87030262.333001.212306.983505.22900HepG2NONO
WDR18ENSG00000065268.6466.27390266.374200.807605.583503.02530HepG2PPIG
WDR18ENSG00000065268.6339.11110135.655301.3217011.260409.83010HepG2PPIL4
WDR18ENSG00000065268.6195.12750409.49600-1.069408.826507.55560HepG2PRPF4
WDR18ENSG00000065268.6109.37310220.04660-1.008602.217801.49210HepG2PRPF8
WDR18ENSG00000065268.6604.46000479.802100.333102.150601.65670HepG2PTBP1
WDR18ENSG00000065268.6622.03630320.824900.9551011.0997010.01430HepG2PUF60
WDR18ENSG00000065268.6668.28330340.557800.9725017.7041016.47120HepG2PUM1
WDR18ENSG00000065268.6476.07940340.316500.484202.616201.96330HepG2PUM2
WDR18ENSG00000065268.6536.60360277.340600.952105.415004.01380HepG2RBM27
WDR18ENSG00000065268.6775.47840533.968700.538205.869905.12930HepG2NELFE
WDR18ENSG00000065268.6477.30570255.739900.900105.001403.94540HepG2RPS2
WDR18ENSG00000065268.6277.57450147.349600.913503.040202.20310HepG2RPS3A
WDR18ENSG00000065268.6425.84000261.099800.705602.319301.34110HepG2RPS5
WDR18ENSG00000065268.681.47650217.65320-1.417604.657403.66750HepG2RRP9
WDR18ENSG00000065268.6367.25080135.444301.439007.212706.24320HepG2SAFB2
WDR18ENSG00000065268.6250.84770138.752100.854204.402502.75790HepG2SART3
WDR18ENSG00000065268.6158.21240292.74820-0.887802.112401.49010HepG2SF3B1
WDR18ENSG00000065268.6596.96710307.596500.956505.987205.01730HepG2SLBP
WDR18ENSG00000065268.6262.99380157.946800.735503.434302.73040HepG2SMN1
WDR18ENSG00000065268.6395.19400206.293600.937804.526103.27800HepG2SMNDC1
WDR18ENSG00000065268.6357.11090196.878500.859003.941202.00480HepG2SND1
WDR18ENSG00000065268.6389.95160934.94620-1.261606.988006.29240HepG2SRFBP1
WDR18ENSG00000065268.6365.21470521.40060-0.513604.143803.59400HepG2SRSF1
WDR18ENSG00000065268.6773.72470316.753501.2884028.1396026.42970HepG2SRSF5
WDR18ENSG00000065268.6327.40890424.19090-0.373602.495001.96480HepG2SRSF9
WDR18ENSG00000065268.6707.10310360.248300.9728017.4118016.06740HepG2SUCLG1
WDR18ENSG00000065268.6198.20640468.66730-1.2416016.3970015.19730HepG2TAF15
WDR18ENSG00000065268.6242.80870147.772300.716302.049801.60610HepG2TIAL1
WDR18ENSG00000065268.6429.94740149.110301.5277014.7599013.60460HepG2TRIM56
WDR18ENSG00000065268.6712.37870313.412801.184502.080001.33240HepG2TUFM
WDR18ENSG00000065268.6234.36260544.75260-1.216904.846804.02820HepG2U2AF1
WDR18ENSG00000065268.6731.97670554.870200.399502.704002.01200HepG2UPF1
WDR18ENSG00000065268.6249.95410131.988000.921204.916503.44230HepG2XPO5
WDR18ENSG00000065268.6489.91280279.715400.808503.471902.66490HepG2XRN2
WDR18ENSG00000065268.6317.32430404.09860-0.348702.099401.50210HepG2ZC3H8
WDR18ENSG00000065268.61115.70190929.983600.262602.376401.84370K562AGGF1
WDR18ENSG00000065268.6613.086601174.97780-0.9385012.2252011.11870K562AQR
WDR18ENSG00000065268.6502.30760351.080200.516702.895201.54480K562BCCIP
WDR18ENSG00000065268.6482.18470339.296200.506903.803402.66760K562BCLAF1
WDR18ENSG00000065268.6906.49400728.390000.315502.700101.60690K562CPEB4
WDR18ENSG00000065268.6446.05150257.406800.793104.136302.80700K562CSTF2
WDR18ENSG00000065268.6774.224201375.82130-0.829503.550302.44190K562CELF1
WDR18ENSG00000065268.6935.59780753.634000.311902.801502.14500K562DDX47
WDR18ENSG00000065268.6739.00150529.028000.482104.853502.95540K562DDX6
WDR18ENSG00000065268.6911.49540664.245400.456402.911502.17720K562EIF2S2
WDR18ENSG00000065268.6218.76160141.457700.628903.249602.38960K562EIF3G
WDR18ENSG00000065268.6347.08740203.030900.773504.936302.35080K562EIF3H
WDR18ENSG00000065268.6132.03830303.45200-1.200506.016804.23980K562FKBP4
WDR18ENSG00000065268.6104.90450166.50440-0.666502.489201.67850K562FMR1
WDR18ENSG00000065268.612.1530081.11830-2.738707.638906.34200K562G3BP2
WDR18ENSG00000065268.6676.01770860.96950-0.348902.940801.76540K562GLRX3
WDR18ENSG00000065268.698.55670221.77590-1.170103.095001.78290K562HNRNPK
WDR18ENSG00000065268.6481.43950222.391801.114202.253201.35570K562IGF2BP2
WDR18ENSG00000065268.6366.07700226.090600.695103.924702.45280K562IGF2BP3
WDR18ENSG00000065268.6179.75160406.83150-1.178407.128204.83920K562ILF2
WDR18ENSG00000065268.661.70130133.40700-1.112502.613001.71040K562KRR1
WDR18ENSG00000065268.6413.74670787.57990-0.928704.335101.69220K562LARP4
WDR18ENSG00000065268.6468.71720233.448201.005505.485604.28770K562MAGOH
WDR18ENSG00000065268.6386.35760232.932500.729903.225502.22290K562MATR3
WDR18ENSG00000065268.6592.98200905.21400-0.610307.653406.36680K562MTPAP
WDR18ENSG00000065268.6431.04660806.36040-0.903607.024405.37210K562NAA15
WDR18ENSG00000065268.6320.66390544.36560-0.763507.748305.72190K562NCBP2
WDR18ENSG00000065268.6547.80360288.643100.924303.111501.71380K562NONO
WDR18ENSG00000065268.6706.513201005.67960-0.509404.527603.60170K562NSUN2
WDR18ENSG00000065268.6260.71800428.12110-0.715503.672302.22970K562PABPC1
WDR18ENSG00000065268.6267.93960520.96670-0.959302.788201.95350K562PCBP3
WDR18ENSG00000065268.6240.08320399.57900-0.734906.137104.94950K562POLR2G
WDR18ENSG00000065268.6838.41590481.670000.799505.614804.37640K562PPIG
WDR18ENSG00000065268.6237.82970396.49450-0.737403.752601.61420K562PPIL4
WDR18ENSG00000065268.6296.34600632.22340-1.093203.518401.39510K562PRPF6
WDR18ENSG00000065268.6510.48480226.830201.1702012.3394010.99010K562PTBP1
WDR18ENSG00000065268.6701.454301298.46170-0.888403.689402.44440K562PUM1
WDR18ENSG00000065268.6559.54970959.55780-0.778105.663004.91940K562PUS1
WDR18ENSG00000065268.6356.66130217.351900.714403.847802.84500K562RBM22
WDR18ENSG00000065268.6349.05130743.45220-1.090804.714002.56740K562RBM39
WDR18ENSG00000065268.6209.39690397.52120-0.924804.854602.70520K562RPS3A
WDR18ENSG00000065268.6297.10380137.379101.112706.679805.04060K562RPS3
WDR18ENSG00000065268.6325.68120552.78990-0.763302.543401.40970K562SF1
WDR18ENSG00000065268.6422.02370992.48950-1.2337020.9153018.85670K562SF3A3
WDR18ENSG00000065268.658.69320148.59810-1.340205.901504.44830K562SF3B1
WDR18ENSG00000065268.6266.01010634.57890-1.254305.507203.57550K562SNRNP200
WDR18ENSG00000065268.6397.03810222.400300.836005.205604.24070K562SRSF1
WDR18ENSG00000065268.6356.74750132.599201.4277013.3417010.88320K562SRSF4
WDR18ENSG00000065268.6440.96250210.117301.069408.536106.59330K562SRSF5
WDR18ENSG00000065268.6308.05160778.80060-1.338105.477902.66820K562SUGP2
WDR18ENSG00000065268.6376.53150759.23810-1.011804.876602.78500K562SUPT6H
WDR18ENSG00000065268.6359.53080225.016700.676004.002603.14430K562TARDBP
WDR18ENSG00000065268.6550.03100217.071601.3412019.6236017.30180K562TIA1
WDR18ENSG00000065268.6425.66090213.170300.997603.134301.96060K562TRA2A
WDR18ENSG00000065268.624.8640078.48500-1.658403.324502.10200K562U2AF1
WDR18ENSG00000065268.617.6245081.10530-2.202206.375605.16270K562U2AF2
WDR18ENSG00000065268.6705.340601066.35090-0.596308.118306.96680K562UPF1
WDR18ENSG00000065268.6507.93390912.43060-0.8451010.842909.06090K562WDR3
WDR18ENSG00000065268.6628.98370948.90570-0.593205.068603.95380K562WDR43
WDR18ENSG00000065268.6348.60480646.90490-0.892003.236601.31380K562XPO5
WDR18ENSG00000065268.6302.95090746.99500-1.302007.723504.54310K562YTHDC2
WDR18ENSG00000065268.6911.262701323.68080-0.538605.998904.64950K562ZC3H8
Gene NameGene IDKDMeanCNMeanlog2(fold change)-log(pval)-log(padj)Cell LineAffected by RBPBound by RBP

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".






The Knockdown/knockout RNA-Seq assay for WDR18 is not available on ENCORE database.





6 RBPs can affect the splicing of WDR18 :

Event TypeGene NameGene IDchrStrandExonStartExonEnd2ndExonStart2ndExonEndupstreamESupstreamEEdownstreamESdownstreamEEdPSIp-valueFDRis_includedCell LineAffected by RBPBound by RBP
SEWDR18ENSG00000065268.6chr19+9940189940879919549921219942119945530.065000.000010.00254includedHepG2RBFOX2
A3SSWDR18ENSG00000065268.6chr19+991954992121991994992121991233991351-0.126000.002800.01735shorterK562AQR
A3SSWDR18ENSG00000065268.6chr19+991954992121991994992121991233991351-0.168000.000000.00011shorterHepG2U2AF1
A5SSWDR18ENSG00000065268.6chr19+9897619901039897619898959902229903640.099000.000000.00000longerK562AQR
A5SSWDR18ENSG00000065268.6chr19+9897619901039897619898959902229903640.310000.000020.00186longerHepG2U2AF2
A5SSWDR18ENSG00000065268.6chr19+9897619901039897619898959902229903640.087000.000000.00103longerHepG2SF3B4
A5SSWDR18ENSG00000065268.6chr19+9897619901039897619898959902229903640.064000.000000.00114longerHepG2SF3A3
A5SSWDR18ENSG00000065268.6chr19+9897619901039897619898959902229903640.106000.000000.00001longerHepG2U2AF1
RIWDR18ENSG00000065268.6chr19+9909159911289909159909959910809911280.098000.000000.00000includedK562AQR

*: "Inf" was shown as "99999.99999" and "-Inf" was shown as "-99999.99999".
**: "-log(0)" was displayed as "99999.99999".





The Knockdown/knockout RNA-Seq assay for WDR18 is not avaliable on ENCORE database.